Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1) - Rat Genome Database

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Gene: Gucy1a1 (guanylate cyclase 1 soluble subunit alpha 1) Ictidomys tridecemlineatus
Analyze
Symbol: Gucy1a1
Name: guanylate cyclase 1 soluble subunit alpha 1
RGD ID: 12728905
Description: ENCODES a protein that exhibits adenylate cyclase activity (ortholog); cytidylate cyclase activity (ortholog); nitric oxide binding (ortholog); INVOLVED IN cGMP biosynthetic process (ortholog); nitric oxide mediated signal transduction (ortholog); positive regulation of nitric oxide mediated signal transduction (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Colonic Neoplasms (ortholog); coronary artery disease (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); guanylate cyclase complex, soluble (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: guanylate cyclase 1 soluble subunit alpha; guanylate cyclase soluble subunit alpha-1; guanylate cyclase soluble subunit alpha-3; Gucy1a3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530137,135,116 - 37,192,728 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365762,353,761 - 2,411,425 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365762,353,874 - 2,411,747 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gucy1a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530137,135,116 - 37,192,728 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365762,353,761 - 2,411,425 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365762,353,874 - 2,411,747 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GUCY1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384155,666,848 - 155,737,059 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4155,666,726 - 155,737,059 (+)EnsemblGRCh38hg38GRCh38
GRCh374156,588,000 - 156,658,211 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364156,807,328 - 156,871,232 (+)NCBINCBI36Build 36hg18NCBI36
Build 344156,945,482 - 157,009,379NCBI
Celera4153,919,477 - 153,989,823 (+)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4152,327,271 - 152,397,264 (+)NCBIHuRef
CHM1_14156,565,607 - 156,635,931 (+)NCBICHM1_1
T2T-CHM13v2.04158,999,647 - 159,069,856 (+)NCBIT2T-CHM13v2.0
Gucy1a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39381,999,734 - 82,053,253 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl381,999,734 - 82,053,096 (-)EnsemblGRCm39 Ensembl
GRCm38382,092,427 - 82,145,946 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl382,092,427 - 82,145,789 (-)EnsemblGRCm38mm10GRCm38
MGSCv37381,896,349 - 81,949,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36382,178,354 - 82,231,000 (-)NCBIMGSCv36mm8
Celera382,117,270 - 82,170,809 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map335.97NCBI
Gucy1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82169,716,684 - 169,780,360 (-)NCBIGRCr8
mRatBN7.22167,418,615 - 167,482,293 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2167,418,640 - 167,481,671 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2174,618,756 - 174,679,844 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02172,639,998 - 172,701,086 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02167,227,585 - 167,288,671 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02181,045,694 - 181,103,321 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2181,045,703 - 181,102,918 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02200,453,480 - 200,515,219 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42173,756,824 - 173,818,316 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12173,705,122 - 173,768,506 (-)NCBI
Celera2161,450,514 - 161,511,622 (-)NCBICelera
Cytogenetic Map2q34NCBI
Gucy1a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547111,367,282 - 11,424,273 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547111,367,318 - 11,422,199 (-)NCBIChiLan1.0ChiLan1.0
GUCY1A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23153,578,326 - 153,648,905 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14153,933,876 - 154,004,517 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04148,032,167 - 148,102,757 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14159,850,092 - 159,920,159 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4159,850,107 - 159,913,338 (+)Ensemblpanpan1.1panPan2
GUCY1A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11553,172,914 - 53,236,200 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1553,174,157 - 53,234,533 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1553,510,720 - 53,570,219 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01553,880,516 - 53,943,086 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1553,881,077 - 53,942,856 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11553,134,895 - 53,194,847 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01553,244,742 - 53,304,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01553,557,797 - 53,618,055 (+)NCBIUU_Cfam_GSD_1.0
GUCY1A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl844,449,290 - 44,518,135 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1844,448,758 - 44,520,737 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2846,457,572 - 46,537,279 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GUCY1A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17102,206,438 - 102,310,535 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7102,238,477 - 102,303,673 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603781,715,008 - 81,968,286 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gucy1a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248482,525,153 - 2,560,025 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248482,522,935 - 2,588,758 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000007453   ⟹   ENSSTOP00000006658
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365762,353,761 - 2,411,243 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000035531   ⟹   ENSSTOP00000029356
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365762,353,761 - 2,411,425 (+)Ensembl
RefSeq Acc Id: XM_040293146   ⟹   XP_040149080
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530137,135,116 - 37,192,728 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040149080 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000006658.2
  ENSSTOP00000029356.1
GenBank Protein KAG3276034 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040149080   ⟸   XM_040293146
- UniProtKB: I3M9R4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000006658   ⟸   ENSSTOT00000007453
RefSeq Acc Id: ENSSTOP00000029356   ⟸   ENSSTOT00000035531
Protein Domains
Guanylate cyclase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000007456 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007453.3 UniProtKB/TrEMBL
  ENSSTOT00000035531.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.450.260 UniProtKB/TrEMBL
  3.30.70.1230 UniProtKB/TrEMBL
  3.90.1520.10 UniProtKB/TrEMBL
  6.10.250.780 UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/TrEMBL
  H-NOX_domain_sf UniProtKB/TrEMBL
  HNOB_dom_associated UniProtKB/TrEMBL
  HNOB_dom_associated_sf UniProtKB/TrEMBL
  NO_sig/Golgi_transp_ligand-bd UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/TrEMBL
NCBI Gene Gucy1a3 ENTREZGENE
PANTHER GUANYLATE CYCLASE SOLUBLE SUBUNIT ALPHA-1 UniProtKB/TrEMBL
  GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 UniProtKB/TrEMBL
Pfam Guanylate_cyc UniProtKB/TrEMBL
  HNOBA UniProtKB/TrEMBL
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/TrEMBL
SMART CYCc UniProtKB/TrEMBL
Superfamily-SCOP SSF111126 UniProtKB/TrEMBL
  SSF55073 UniProtKB/TrEMBL
UniProt I3M9R4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-28 Gucy1a1  guanylate cyclase 1 soluble subunit alpha 1  Gucy1a3  guanylate cyclase 1 soluble subunit alpha  Symbol and/or name change 5135510 APPROVED