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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:bifonazole
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Accession:CHEBI:31286 term browser browse the term
Definition:A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections.
Synonyms:exact_synonym: rac-1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole
 related_synonym: (+-)-1-(p,alpha-Diphenylbenzyl)imidazole;   (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole;   (RS)-bifonazole;   1-((4-Biphenylyl)phenylmethyl)-1H-imidazole;   1-(alpha-(4-Biphenylyl)benzyl)imidazole;   Formula=C22H18N2;   Mycospor;   bifonazol;   bifonazolum;   rac-bifonazole;   racemic bifonazole
 xref: CAS:60628-96-8;   DrugBank:DB04794;   HMDB:HMDB0015583;   KEGG:D01775
 xref_mesh: MESH:C036596
 xref: PMID:21746947;   PMID:23066185;   PMID:23283047;   PMID:23467055;   PMID:23586591;   PMID:24215461;   PMID:24849495;   Reaxys:618427;   Wikipedia:Bifonazole



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bifonazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO bifonazole results in decreased activity of CYP19A1 protein CTD PMID:15554355 PMID:24496634 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO bifonazole results in decreased activity of CYP3A4 protein CTD PMID:15135088 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO bifonazole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      chemical substance 13190
        mixture 12396
          racemate 10478
            bifonazole 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                organic heterocyclic compound 18584
                                  heteroarene 16542
                                    monocyclic heteroarene 13505
                                      azole 12710
                                        diazole 8598
                                          imidazoles 7695
                                            1-[biphenyl-4-yl(phenyl)methyl]imidazole 3
                                              (R)-bifonazole 3
                                                bifonazole 3
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