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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:bifonazole
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Accession:CHEBI:31286 term browser browse the term
Definition:A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections.
Synonyms:exact_synonym: rac-1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole
 related_synonym: (+-)-1-(p,alpha-Diphenylbenzyl)imidazole;   (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole;   (RS)-bifonazole;   1-((4-Biphenylyl)phenylmethyl)-1H-imidazole;   1-(alpha-(4-Biphenylyl)benzyl)imidazole;   Formula=C22H18N2;   Mycospor;   bifonazol;   bifonazolum;   rac-bifonazole;   racemic bifonazole
 xref: CAS:60628-96-8;   DrugBank:DB04794;   HMDB:HMDB0015583;   KEGG:D01775
 xref_mesh: MESH:C036596
 xref: PMID:21746947;   PMID:23066185;   PMID:23283047;   PMID:23467055;   PMID:23586591;   PMID:24215461;   PMID:24849495;   Reaxys:618427;   Wikipedia:Bifonazole


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bifonazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO bifonazole results in decreased activity of CYP19A1 protein CTD PMID:15554355, PMID:24496634 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases activity ISO bifonazole results in decreased activity of CYP51A1 protein CTD PMID:16989930 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      chemical substance 11928
        mixture 10845
          racemate 9741
            bifonazole 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  heteroarene 16447
                                    monocyclic heteroarene 13303
                                      azole 12471
                                        diazole 8126
                                          imidazoles 7655
                                            1-[biphenyl-4-yl(phenyl)methyl]imidazole 2
                                              (R)-bifonazole 2
                                                bifonazole 2
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