Id4 (inhibitor of DNA binding 4) - Rat Genome Database

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Gene: Id4 (inhibitor of DNA binding 4) Rattus norvegicus
Analyze
Symbol: Id4
Name: inhibitor of DNA binding 4
RGD ID: 631428
Description: Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; transcription corepressor activity; and transcription regulator inhibitor activity. Predicted to be involved in circadian rhythm; negative regulation of transcription by RNA polymerase II; and neuron differentiation. Predicted to act upstream of or within several processes, including central nervous system development; gland morphogenesis; and negative regulation of cell differentiation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ID4 (inhibitor of DNA binding 4); PARTICIPATES IN transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DNA-binding protein inhibitor ID-4; Idb4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; inhibitor of DNA binding 4, HLH protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81716,595,724 - 16,598,293 (-)NCBIGRCr8
mRatBN7.21716,389,387 - 16,391,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1716,389,387 - 16,392,470 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1716,269,665 - 16,272,236 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01717,873,494 - 17,876,065 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01716,195,273 - 16,197,843 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01716,692,557 - 16,695,126 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1716,692,557 - 16,695,126 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01718,744,511 - 18,747,080 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41722,525,292 - 22,527,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11722,525,291 - 22,527,861 (-)NCBI
Celera1716,113,430 - 16,115,946 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,3-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphotericin B  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
avobenzone  (ISO)
belinostat  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium dichloride  (EXP,ISO)
captan  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flutamide  (EXP)
folpet  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
GW 4064  (ISO)
hydroquinone  (ISO)
inulin  (ISO)
ketoconazole  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (EXP)
mitomycin C  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
nimesulide  (EXP)
nitrofen  (EXP)
ochratoxin A  (EXP)
omacetaxine mepesuccinate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
PhIP  (EXP)
progesterone  (ISO)
raloxifene  (ISO)
ranitidine  (EXP)
resveratrol  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
triticonazole  (EXP)
troglitazone  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Id4 regulates mammary epithelial cell growth and differentiation and is overexpressed in rat mammary gland carcinomas. Shan L, etal., Am J Pathol 2003 Dec;163(6):2495-502.
Additional References at PubMed
PMID:9418957   PMID:11136250   PMID:15469968   PMID:15882580   PMID:16304207   PMID:16862533   PMID:18498089   PMID:19217292   PMID:20460371   PMID:20628571   PMID:21132377   PMID:21543770  
PMID:22041901   PMID:23786676   PMID:28278052  


Genomics

Comparative Map Data
Id4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81716,595,724 - 16,598,293 (-)NCBIGRCr8
mRatBN7.21716,389,387 - 16,391,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1716,389,387 - 16,392,470 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1716,269,665 - 16,272,236 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01717,873,494 - 17,876,065 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01716,195,273 - 16,197,843 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01716,692,557 - 16,695,126 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1716,692,557 - 16,695,126 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01718,744,511 - 18,747,080 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41722,525,292 - 22,527,861 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11722,525,291 - 22,527,861 (-)NCBI
Celera1716,113,430 - 16,115,946 (-)NCBICelera
Cytogenetic Map17p14NCBI
ID4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38619,837,370 - 19,842,197 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl619,837,370 - 19,842,197 (+)EnsemblGRCh38hg38GRCh38
GRCh37619,837,601 - 19,842,428 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36619,945,596 - 19,948,894 (+)NCBINCBI36Build 36hg18NCBI36
Build 34619,945,595 - 19,948,893NCBI
Celera621,070,861 - 21,074,159 (+)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef619,782,014 - 19,786,844 (+)NCBIHuRef
CHM1_1619,839,766 - 19,844,596 (+)NCBICHM1_1
T2T-CHM13v2.0619,709,014 - 19,713,841 (+)NCBIT2T-CHM13v2.0
Id4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391348,414,592 - 48,419,504 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1348,414,704 - 48,419,502 (+)EnsemblGRCm39 Ensembl
GRCm381348,261,116 - 48,266,028 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1348,261,228 - 48,266,026 (+)EnsemblGRCm38mm10GRCm38
MGSCv371348,356,796 - 48,359,405 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361348,273,364 - 48,275,973 (+)NCBIMGSCv36mm8
Celera1349,350,381 - 49,353,061 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1324.71NCBI
Id4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554836,600,867 - 6,602,564 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554836,598,804 - 6,601,496 (-)NCBIChiLan1.0ChiLan1.0
ID4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2534,476,360 - 34,479,706 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1630,475,737 - 30,479,077 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0619,665,197 - 19,668,517 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ID4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13518,358,518 - 18,360,767 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3518,357,826 - 18,359,011 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3518,357,826 - 18,359,011 (+)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3518,306,552 - 18,309,524 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03518,464,103 - 18,467,094 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3518,463,709 - 18,465,771 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13518,276,216 - 18,279,196 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03518,339,930 - 18,342,928 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03519,757,627 - 19,760,617 (+)NCBIUU_Cfam_GSD_1.0
ID4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl715,281,757 - 15,282,839 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1715,281,535 - 15,284,895 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2716,178,362 - 16,181,445 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ID4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11752,349,908 - 52,353,218 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1752,348,388 - 52,353,281 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604420,104,714 - 20,109,525 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Id4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247566,814,842 - 6,819,578 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247566,816,364 - 6,819,144 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Id4
7 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:474
Count of miRNA genes:247
Interacting mature miRNAs:303
Transcripts:ENSRNOT00000021550
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)171398677321975515Rat
1331720Rf43Renal function QTL 432.881kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)171533061323017269Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat

Markers in Region
RH144051  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21716,390,592 - 16,390,740 (+)MAPPERmRatBN7.2
Rnor_6.01716,693,763 - 16,693,910NCBIRnor6.0
Rnor_5.01718,745,717 - 18,745,864UniSTSRnor5.0
RGSC_v3.41722,526,498 - 22,526,645UniSTSRGSC3.4
Celera1716,114,636 - 16,114,783UniSTS
RH 3.4 Map17181.3UniSTS
Cytogenetic Map17p14UniSTS
BE116739  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21716,389,909 - 16,390,085 (+)MAPPERmRatBN7.2
Rnor_6.01716,693,080 - 16,693,255NCBIRnor6.0
Rnor_5.01718,745,034 - 18,745,209UniSTSRnor5.0
RGSC_v3.41722,525,815 - 22,525,990UniSTSRGSC3.4
Celera1716,113,953 - 16,114,128UniSTS
RH 3.4 Map17184.2UniSTS
Cytogenetic Map17p14UniSTS
PMC133998P7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21716,391,146 - 16,391,956 (+)MAPPERmRatBN7.2
Rnor_6.01716,694,317 - 16,695,126NCBIRnor6.0
Rnor_5.01718,746,271 - 18,747,080UniSTSRnor5.0
RGSC_v3.41722,527,052 - 22,527,861UniSTSRGSC3.4
Cytogenetic Map17p14UniSTS
Idb4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21716,390,494 - 16,391,962 (+)MAPPERmRatBN7.2
Rnor_6.01716,693,665 - 16,695,132NCBIRnor6.0
Rnor_5.01718,745,619 - 18,747,086UniSTSRnor5.0
RGSC_v3.41722,526,400 - 22,527,867UniSTSRGSC3.4
Celera1716,115,188 - 16,115,803UniSTS
Cytogenetic Map17p14UniSTS
Idb4  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81716,597,481 - 16,598,097 (+)Marker Load Pipeline
mRatBN7.21716,391,144 - 16,391,760 (+)MAPPERmRatBN7.2
Rnor_6.01716,694,315 - 16,694,930NCBIRnor6.0
Rnor_5.01718,746,269 - 18,746,884UniSTSRnor5.0
RGSC_v3.41722,527,050 - 22,527,665UniSTSRGSC3.4
Celera1716,115,188 - 16,115,803UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000021550   ⟹   ENSRNOP00000021550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1716,389,387 - 16,392,470 (-)Ensembl
Rnor_6.0 Ensembl1716,692,557 - 16,695,126 (-)Ensembl
RefSeq Acc Id: NM_175582   ⟹   NP_783172
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81716,595,724 - 16,598,293 (-)NCBI
mRatBN7.21716,389,387 - 16,391,956 (-)NCBI
Rnor_6.01716,692,557 - 16,695,126 (-)NCBI
Rnor_5.01718,744,511 - 18,747,080 (-)NCBI
RGSC_v3.41722,525,292 - 22,527,861 (-)RGD
Celera1716,113,430 - 16,115,946 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_783172 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAO15695 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021550
  ENSRNOP00000021550.2
RefSeq Acc Id: NP_783172   ⟸   NM_175582
- UniProtKB: E9PU21 (UniProtKB/TrEMBL),   Q8CH17 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021550   ⟸   ENSRNOT00000021550
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PU21-F1-model_v2 AlphaFold E9PU21 1-161 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631428 AgrOrtholog
BioCyc Gene G2FUF-9952 BioCyc
Ensembl Genes ENSRNOG00000016099 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021550 ENTREZGENE
  ENSRNOT00000021550.3 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro DNA-bd_prot-inh UniProtKB/TrEMBL
  HLH_DNA-bd UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:291023 UniProtKB/TrEMBL
NCBI Gene 291023 ENTREZGENE
PANTHER DNA-BINDING PROTEIN INHIBITOR ID-4 UniProtKB/TrEMBL
  PTHR11723 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PhenoGen Id4 PhenoGen
PROSITE HLH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016099 RatGTEx
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP HLH_basic UniProtKB/TrEMBL
UniProt E9PU21 ENTREZGENE, UniProtKB/TrEMBL
  Q8CH17 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-13 Id4  inhibitor of DNA binding 4  Id4  inhibitor of DNA binding 4, HLH protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-15 Id4  inhibitor of DNA binding 4, HLH protein  Id4  inhibitor of DNA binding 4, dominant negative helix-loop-helix protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-25 Id4  inhibitor of DNA binding 4, dominant negative helix-loop-helix protein  Id4  inhibitor of DNA binding 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Id4  inhibitor of DNA binding 4  Idb4    Symbol updated 1299863 APPROVED
2004-02-11 Idb4  inhibitor of DNA binding 4      Symbol and Name status set to approved 625702 APPROVED