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Gene: Scp2 (sterol carrier protein 2) Rattus norvegicus
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Symbol: Scp2
Name: sterol carrier protein 2
Description: Exhibits acetyl-CoA C-acyltransferase activity; identical protein binding activity; and lipid transfer activity. Involved in several processes, including cellular response to cholesterol; positive regulation of cholesterol biosynthetic process; and positive regulation of cholesterol import. Localizes to several cellular components, including the endoplasmic reticulum; extrinsic component of mitochondrial outer membrane; and peroxisomal matrix. Orthologous to human SCP2 (sterol carrier protein 2); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: non-specific lipid-transfer protein; NSL-TP; NSLIPTR; propanoyl-CoA C-acyltransferase; SCP-2; SCP-chi; SCP-X; SCPx; Sterol carrier protein 2 liver; Sterol carrier protein 2, liver; sterol carrier protein X
Orthologs:
Homo sapiens (human) : SCP2 (sterol carrier protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Scp2 (sterol carrier protein 2, liver)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scp2 (sterol carrier protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SCP2 (sterol carrier protein 2)
Canis lupus familiaris (dog) : SCP2 (sterol carrier protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scp2 (sterol carrier protein 2)
Sus scrofa (pig) : SCP2 (sterol carrier protein 2)
Chlorocebus sabaeus (African green monkey) : SCP2 (sterol carrier protein 2)
Heterocephalus glaber (naked mole-rat) : Scp2 (sterol carrier protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05127,647,934 - 127,735,703 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5127,620,274 - 127,735,739 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05131,495,401 - 131,584,291 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45129,152,836 - 129,230,401 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15129,158,061 - 129,235,617 (-)NCBI
Celera5121,551,168 - 121,624,570 (-)NCBICelera
Cytogenetic Map5q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Scp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3642
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.