SCP2 (sterol carrier protein 2) - Rat Genome Database

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Gene: SCP2 (sterol carrier protein 2) Canis lupus familiaris
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Symbol: SCP2
Name: sterol carrier protein 2
RGD ID: 12314764
Description: ENCODES a protein that exhibits acetyl-CoA C-acyltransferase activity (ortholog); acetyl-CoA C-myristoyltransferase activity (ortholog); cholesterol transfer activity (ortholog); INVOLVED IN aging (ortholog); bile acid metabolic process (ortholog); cellular response to cholesterol (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH dystonia (ortholog); Experimental Diabetes Mellitus (ortholog); Leukoencephalopathies (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: non-specific lipid-transfer protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1555,860,053 - 55,971,657 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl555,860,549 - 55,964,014 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha555,925,974 - 56,029,762 (-)NCBI
ROS_Cfam_1.0556,049,398 - 56,153,726 (-)NCBI
UMICH_Zoey_3.1556,041,491 - 56,145,154 (-)NCBI
UNSW_CanFamBas_1.0555,932,897 - 56,036,796 (-)NCBI
UU_Cfam_GSD_1.0556,322,159 - 56,425,975 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
SCP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1555,860,053 - 55,971,657 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl555,860,549 - 55,964,014 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha555,925,974 - 56,029,762 (-)NCBI
ROS_Cfam_1.0556,049,398 - 56,153,726 (-)NCBI
UMICH_Zoey_3.1556,041,491 - 56,145,154 (-)NCBI
UNSW_CanFamBas_1.0555,932,897 - 56,036,796 (-)NCBI
UU_Cfam_GSD_1.0556,322,159 - 56,425,975 (-)NCBI
SCP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl152,927,276 - 53,051,698 (+)EnsemblGRCh38hg38GRCh38
GRCh38152,927,276 - 53,051,698 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37153,392,948 - 53,517,370 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36153,165,536 - 53,289,870 (+)NCBINCBI36hg18NCBI36
Build 34153,104,968 - 53,229,303NCBI
Celera151,680,710 - 51,805,264 (+)NCBI
Cytogenetic Map1p32.3NCBI
HuRef151,508,548 - 51,632,772 (+)NCBIHuRef
CHM1_1153,510,076 - 53,634,447 (+)NCBICHM1_1
Scp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394107,901,027 - 108,002,168 (-)NCBIGRCm39mm39
GRCm39 Ensembl4107,901,036 - 108,002,195 (-)Ensembl
GRCm384108,043,830 - 108,144,971 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4108,043,839 - 108,144,998 (-)EnsemblGRCm38mm10GRCm38
MGSCv374107,716,444 - 107,791,104 (-)NCBIGRCm37mm9NCBIm37
MGSCv364107,541,771 - 107,616,433 (-)NCBImm8
Celera4106,393,462 - 106,469,326 (-)NCBICelera
Cytogenetic Map4C7NCBI
cM Map450.2NCBI
Scp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25122,806,949 - 122,881,259 (-)NCBI
Rnor_6.0 Ensembl5127,620,274 - 127,735,739 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05127,647,934 - 127,735,703 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05131,495,401 - 131,584,291 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45129,152,836 - 129,230,401 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15129,158,061 - 129,235,617 (-)NCBI
Celera5121,551,168 - 121,624,570 (-)NCBICelera
Cytogenetic Map5q34NCBI
Scp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554646,094,758 - 6,224,287 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554646,097,241 - 6,224,287 (-)NCBIChiLan1.0ChiLan1.0
SCP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1153,797,256 - 53,924,939 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl153,797,254 - 53,924,939 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0152,195,491 - 52,324,227 (+)NCBIMhudiblu_PPA_v0panPan3
Scp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505867,305,291 - 67,411,787 (+)NCBI
SpeTri2.0NW_0049365228,004,503 - 8,110,995 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.16159,191,045 - 159,314,985 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26147,007,365 - 147,077,789 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SCP2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12079,868,825 - 79,993,906 (-)NCBI
ChlSab1.1 Ensembl2079,865,332 - 79,993,835 (-)Ensembl
Scp2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624859106,405 - 252,870 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 10 6
Low 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000046744   ⟹   ENSCAFP00000041481
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl555,860,549 - 55,964,014 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000091004   ⟹   ENSCAFP00000054579
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl555,860,549 - 55,964,014 (-)Ensembl
RefSeq Acc Id: XM_022418866   ⟹   XP_022274574
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1555,860,053 - 55,971,657 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038476342   ⟹   XP_038332270
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1556,041,491 - 56,145,154 (-)NCBI
RefSeq Acc Id: XM_038476343   ⟹   XP_038332271
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1556,041,491 - 56,144,648 (-)NCBI
RefSeq Acc Id: XM_038521201   ⟹   XP_038377129
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha555,925,974 - 56,029,258 (-)NCBI
RefSeq Acc Id: XM_038537506   ⟹   XP_038393434
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0556,322,159 - 56,425,975 (-)NCBI
RefSeq Acc Id: XM_038601656   ⟹   XP_038457584
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0555,932,897 - 56,036,796 (-)NCBI
RefSeq Acc Id: XM_038601657   ⟹   XP_038457585
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0555,932,897 - 56,036,298 (-)NCBI
RefSeq Acc Id: XM_038666224   ⟹   XP_038522152
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0556,049,398 - 56,153,726 (-)NCBI
RefSeq Acc Id: XM_038666225   ⟹   XP_038522153
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0556,049,398 - 56,153,215 (-)NCBI
RefSeq Acc Id: XM_860991   ⟹   XP_866084
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1555,860,053 - 55,964,043 (-)NCBI
Dog10K_Boxer_Tasha555,925,974 - 56,029,762 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_866084   ⟸   XM_860991
- Peptide Label: isoform X1
- UniProtKB: J9P746 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022274574   ⟸   XM_022418866
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000041481   ⟸   ENSCAFT00000046744
RefSeq Acc Id: ENSCAFP00000054579   ⟸   ENSCAFT00000091004
RefSeq Acc Id: XP_038332270   ⟸   XM_038476342
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038332271   ⟸   XM_038476343
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038457584   ⟸   XM_038601656
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038457585   ⟸   XM_038601657
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038522152   ⟸   XM_038666224
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038522153   ⟸   XM_038666225
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038377129   ⟸   XM_038521201
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038393434   ⟸   XM_038537506
- Peptide Label: isoform X2
Protein Domains
SCP2   Thiolase_C   Thiolase_N

Promoters
RGD ID:13683326
Promoter ID:EPDNEW_C1394
Type:multiple initiation site
Name:SCP2_1
Description:sterol carrier protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1555,964,023 - 55,964,083EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000032423 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000041481 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000054579 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000046744 UniProtKB/TrEMBL
  ENSCAFT00000091004 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1050.10 UniProtKB/TrEMBL
  3.40.47.10 UniProtKB/TrEMBL
InterPro SCP2_sterol-bd_dom UniProtKB/TrEMBL
  SCP2_sterol-bd_dom_sf UniProtKB/TrEMBL
  Thiolase-like UniProtKB/TrEMBL
  Thiolase_acyl_enz_int_AS UniProtKB/TrEMBL
  Thiolase_C UniProtKB/TrEMBL
  Thiolase_CS UniProtKB/TrEMBL
  Thiolase_N UniProtKB/TrEMBL
NCBI Gene SCP2 ENTREZGENE
Pfam SCP2 UniProtKB/TrEMBL
  Thiolase_C UniProtKB/TrEMBL
  Thiolase_N UniProtKB/TrEMBL
PROSITE THIOLASE_1 UniProtKB/TrEMBL
  THIOLASE_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53901 UniProtKB/TrEMBL
  SSF55718 UniProtKB/TrEMBL
UniProt A0A5F4CP61_CANLF UniProtKB/TrEMBL
  J9P746 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:45930 ENTREZGENE