Camk1 (calcium/calmodulin-dependent protein kinase I) - Rat Genome Database

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Gene: Camk1 (calcium/calmodulin-dependent protein kinase I) Rattus norvegicus
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Symbol: Camk1
Name: calcium/calmodulin-dependent protein kinase I
RGD ID: 629473
Description: Enables calcium/calmodulin-dependent protein kinase activity. Involved in regulation of synapse organization. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human CAMK1 (calcium/calmodulin dependent protein kinase I); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: calcium/calmodulin-dependent protein kinase type 1; caM kinase I alpha; caM-KI; Camki; caMKI-alpha; G alpha interacting protein; Gaip; regulator of G-protein signalling 19
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84148,036,843 - 148,047,675 (-)NCBIGRCr8
mRatBN7.24146,481,196 - 146,492,039 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,481,196 - 146,492,081 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4151,865,404 - 151,875,694 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04147,646,247 - 147,656,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,267,793 - 146,278,095 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,289,300 - 145,300,146 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,288,996 - 145,300,177 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04208,586,449 - 208,597,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44149,220,661 - 149,229,168 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14149,465,501 - 149,474,009 (-)NCBI
Celera4135,038,512 - 135,048,763 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Camk1RatAtrioventricular Septal Defect 2  ISOCAMK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Atrioventricular septal defect more ...ClinVarPMID:28492532
Camk1Ratlong QT syndrome  ISOCAMK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:28492532
Camk1Ratmyoclonic-atonic epilepsy  ISOCAMK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Generalized myoclonic-atonic seizureClinVarPMID:25865495 more ...
Camk1RatNeurodevelopmental Disorders  ISOCAMK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Camk1Ratnonpapillary renal cell carcinoma  ISOCAMK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Nonpapillary renal cell carcinomaClinVar 

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Object Symbol
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Reference
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Source
Original Reference(s)
Camk1Rat1,1-dichloroethene increases expressionISOCamk1 (Mus musculus)6480464vinylidene chloride results in increased expression of CAMK1 mRNACTDPMID:26682919
Camk1Rat1,2-dimethylhydrazine increases expressionISOCamk1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of CAMK1 mRNACTDPMID:22206623
Camk1Rat17alpha-ethynylestradiol multiple interactionsISOCamk1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CAMK1 mRNACTDPMID:17942748
Camk1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCamk1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CAMK1 mRNACTDPMID:17942748
Camk1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CAMK1 mRNACTDPMID:33387578
Camk1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of CAMK1 mRNACTDPMID:34747641
Camk1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCamk1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CAMK1 mRNACTDPMID:21570461
Camk1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of CAMK1 mRNACTDPMID:21215274
Camk1Rat3,3',4,4',5-pentachlorobiphenyl decreases expressionEXP 64804643 more ...CTDPMID:32119087
Camk1Rat3,4-methylenedioxymethamphetamine increases expressionISOCamk1 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CAMK1 mRNACTDPMID:26251327
Camk1Rat4,4'-sulfonyldiphenol increases expressionISOCamk1 (Mus musculus)6480464bisphenol S results in increased expression of CAMK1 mRNACTDPMID:39298647
Camk1Rat4,4'-sulfonyldiphenol increases expressionISOCAMK1 (Homo sapiens)6480464bisphenol S results in increased expression of CAMK1 proteinCTDPMID:34186270
Camk1Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of CAMK1 mRNACTDPMID:36041667
Camk1Rat4-hydroxyphenyl retinamide decreases expressionISOCamk1 (Mus musculus)6480464Fenretinide results in decreased expression of CAMK1 mRNACTDPMID:28973697
Camk1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of CAMK1 mRNACTDPMID:24780913
Camk1Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of CAMK1 mRNACTDPMID:31881176
Camk1Rataconitine increases expressionEXP 6480464Aconitine results in increased expression of CAMK1 proteinCTDPMID:33236894
Camk1Ratacrylamide decreases expressionISOCAMK1 (Homo sapiens)6480464Acrylamide results in decreased expression of CAMK1 mRNACTDPMID:32763439
Camk1Ratafimoxifene decreases response to substanceISOCAMK1 (Homo sapiens)6480464CAMK1 results in decreased susceptibility to afimoxifeneCTDPMID:21233418
Camk1Ratall-trans-retinoic acid increases expressionISOCAMK1 (Homo sapiens)6480464Tretinoin results in increased expression of CAMK1 mRNACTDPMID:15498508 and PMID:15894607

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Biological Process
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Original Reference(s)
Camk1Ratcell differentiation involved_inIEAUniProtKB-KW:KW-02211600115GO_REF:0000043UniProtGO_REF:0000043
Camk1Ratintracellular signal transduction involved_inIEAUniProtKB:Q14012 and ensembl:ENSP000002564601600115GO_REF:0000107EnsemblGO_REF:0000107
Camk1Ratintracellular signal transduction involved_inISOCAMK1 (Homo sapiens)1624291 PMID:23867755RGDPMID:23867755
Camk1Ratnervous system development involved_inIEAUniProtKB-KW:KW-05241600115GO_REF:0000043UniProtGO_REF:0000043
Camk1Ratnucleocytoplasmic transport acts_upstream_of_or_withinISOCamk1 (Mus musculus)1624291MGI:3036234 PMID:12130539 and PMID:18332106RGDPMID:12130539 and PMID:18332106
Camk1Ratnucleocytoplasmic transport acts_upstream_of_or_withinIEAUniProtKB:Q91YS8 and ensembl:ENSMUSP000000324091600115GO_REF:0000107EnsemblGO_REF:0000107
Camk1Ratpositive regulation of dendritic spine development involved_inISSUniProtKB:Q140121600115GO_REF:0000024UniProtGO_REF:0000024
Camk1Ratpositive regulation of dendritic spine development involved_inISOCAMK1 (Homo sapiens)1624291 PMID:18184567RGDPMID:18184567
Camk1Ratpositive regulation of dendritic spine development involved_inIEAUniProtKB:Q14012 and ensembl:ENSP000002564601600115GO_REF:0000107EnsemblGO_REF:0000107
Camk1Ratpositive regulation of muscle cell differentiation involved_inISOCAMK1 (Homo sapiens)1624291 PMID:11081517RGDPMID:11081517
Camk1Ratpositive regulation of muscle cell differentiation involved_inIEAUniProtKB:Q14012 and ensembl:ENSP000002564601600115GO_REF:0000107EnsemblGO_REF:0000107
Camk1Ratpositive regulation of neuron projection development involved_inISSUniProtKB:Q140121600115GO_REF:0000024UniProtGO_REF:0000024
Camk1Ratpositive regulation of neuron projection development involved_inISOCAMK1 (Homo sapiens)1624291 PMID:17442826RGDPMID:17442826
Camk1Ratpositive regulation of neuron projection development involved_inIEAUniProtKB:Q14012 and ensembl:ENSP000002564601600115GO_REF:0000107EnsemblGO_REF:0000107
Camk1Ratpositive regulation of protein export from nucleus involved_inIEAUniProtKB:Q14012 and ensembl:ENSP000002564601600115GO_REF:0000107EnsemblGO_REF:0000107
Camk1Ratpositive regulation of protein export from nucleus acts_upstream_of_or_withinIEAUniProtKB:Q91YS8 and ensembl:ENSMUSP000000324091600115GO_REF:0000107EnsemblGO_REF:0000107
Camk1Ratpositive regulation of protein export from nucleus acts_upstream_of_or_withinISOCamk1 (Mus musculus)1624291 PMID:11081517RGDPMID:11081517
Camk1Ratpositive regulation of protein export from nucleus involved_inISOCAMK1 (Homo sapiens)1624291 PMID:23867755RGDPMID:23867755
Camk1Ratpositive regulation of protein serine/threonine kinase activity involved_inISSUniProtKB:Q140121600115GO_REF:0000024UniProtGO_REF:0000024
Camk1Ratpositive regulation of protein serine/threonine kinase activity involved_inISOCAMK1 (Homo sapiens)1624291 PMID:17442826RGDPMID:17442826
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Cellular Component
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Reference
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Original Reference(s)
Camk1Ratcytoplasm is_active_inIBACGD:CAL0000193471 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Camk1Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Camk1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Camk1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9619772ReactomeReactome:R-RNO-9619772
Camk1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9619472ReactomeReactome:R-RNO-9619472
Camk1Ratcytosol located_inTAS 1600115Reactome:R-NUL-9619413ReactomeReactome:R-NUL-9619413
Camk1Ratglutamatergic synapse is_active_inIDA 13702161PMID:18184567SynGO 
Camk1Ratglutamatergic synapse is_active_inIEP 13702161PMID:18184567SynGO 
Camk1Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Camk1Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Camk1Ratpostsynaptic density is_active_inIEP 13702161PMID:18184567SynGO 
Camk1Ratpostsynaptic density is_active_inIDA 13702161PMID:18184567SynGO 
Camk1Ratpostsynaptic density is_active_inIBAPANTHER:PTN002805037 and Camk1 (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
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Molecular Function
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Object Symbol
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Original Reference(s)
Camk1RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Camk1RatATP binding enablesIEAInterPro:IPR000719 and InterPro:IPR0174411600115GO_REF:0000002InterProGO_REF:0000002
Camk1RatATP binding enablesIEAInterPro:IPR0007191600115GO_REF:0000002InterProGO_REF:0000002
Camk1RatATP binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
Camk1Ratcalcium/calmodulin-dependent protein kinase activity  IDA 625618 RGD 
Camk1Ratcalcium/calmodulin-dependent protein kinase activity enablesIEAEC:2.7.11.171600115GO_REF:0000003UniProtGO_REF:0000003
Camk1Ratcalcium/calmodulin-dependent protein kinase activity enablesIBAMGI:2388073 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Camk1Ratcalcium/calmodulin-dependent protein kinase activity enablesIDA 8554378PMID:17939993UniProt 
Camk1Ratcalmodulin binding enablesIBAPANTHER:PTN001218105 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Camk1Ratcalmodulin binding enablesIEAUniProtKB-KW:KW-01121600115GO_REF:0000043UniProtGO_REF:0000043
Camk1Ratcatalytic activity enablesIEAUniProtKB-KW:KW-00211600115GO_REF:0000043UniProtGO_REF:0000043
Camk1Ratkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
Camk1Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Camk1Ratnucleotide binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
Camk1Ratprotein binding enablesIPIUniProtKB:Q9R1U58554378PMID:17939993UniProt 
Camk1Ratprotein binding enablesISOCamk1 (Mus musculus)1624291PR:Q9DBB1 more ...RGDPMID:15284227 and PMID:25915125
Camk1Ratprotein binding enablesISOCAMK1 (Homo sapiens)1624291UniProtKB:P42858 more ...RGDPMID:17442826 more ...
Camk1Ratprotein kinase activity enablesIEAInterPro:IPR000719 and InterPro:IPR0082711600115GO_REF:0000002InterProGO_REF:0000002
Camk1Ratprotein kinase activity enablesIEAARBA:ARBA000270181600115GO_REF:0000117UniProtGO_REF:0000117
Camk1Ratprotein serine kinase activity enablesIEARHEA:179891600115GO_REF:0000116RHEAGO_REF:0000116
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1 to 10 of 10 rows
#
Reference Title
Reference Citation
1. Characterization of a rat cDNA clone encoding calcium/calmodulin-dependent protein kinase I. Cho FS, etal., Biochim Biophys Acta 1994 Oct 20;1224(1):156-60.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Calcium/calmodulin-dependent protein kinase I. cDNA cloning and identification of autophosphorylation site. Picciotto MR, etal., J Biol Chem 1993 Dec 15;268(35):26512-21.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex. Saneyoshi T, etal., Neuron. 2008 Jan 10;57(1):94-107. doi: 10.1016/j.neuron.2007.11.016.
8. SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. Sjostrom M, etal., Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16922-7. Epub 2007 Oct 15.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Activation of Ca2+/calmodulin-dependent protein kinase I in cultured rat hippocampal neurons. Uezu A, etal., J Neurochem 2002 Aug;82(3):585-93.
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PMID:1646483   PMID:7624832   PMID:7698321   PMID:8386178   PMID:8601311   PMID:8621702   PMID:8631893   PMID:8702851   PMID:10936699   PMID:11081517   PMID:11114197   PMID:11264466  
PMID:12081505   PMID:12130539   PMID:12475216   PMID:15084659   PMID:15147908   PMID:15150258   PMID:15251453   PMID:15489334   PMID:15793568   PMID:16054096   PMID:16683702   PMID:17442826  
PMID:18332106   PMID:18524905   PMID:19200342   PMID:19292454   PMID:20534813   PMID:20810878   PMID:21255668   PMID:22745633   PMID:22833565   PMID:23867755   PMID:26386307   PMID:27323839  
PMID:27369073   PMID:34875535  



Camk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84148,036,843 - 148,047,675 (-)NCBIGRCr8
mRatBN7.24146,481,196 - 146,492,039 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4146,481,196 - 146,492,081 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4151,865,404 - 151,875,694 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04147,646,247 - 147,656,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04146,267,793 - 146,278,095 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04145,289,300 - 145,300,146 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,288,996 - 145,300,177 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04208,586,449 - 208,597,283 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44149,220,661 - 149,229,168 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14149,465,501 - 149,474,009 (-)NCBI
Celera4135,038,512 - 135,048,763 (-)NCBICelera
Cytogenetic Map4q42NCBI
CAMK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3839,757,347 - 9,769,947 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl39,757,347 - 9,769,992 (-)EnsemblGRCh38hg38GRCh38
GRCh3739,799,031 - 9,811,631 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3639,774,031 - 9,786,661 (-)NCBINCBI36Build 36hg18NCBI36
Build 3439,774,031 - 9,786,661NCBI
Celera39,733,733 - 9,746,362 (-)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef39,735,376 - 9,748,016 (-)NCBIHuRef
CHM1_139,749,224 - 9,761,863 (-)NCBICHM1_1
T2T-CHM13v2.039,749,303 - 9,761,902 (-)NCBIT2T-CHM13v2.0
Camk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396113,311,085 - 113,320,883 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6113,311,085 - 113,320,945 (-)EnsemblGRCm39 Ensembl
GRCm386113,334,124 - 113,343,922 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6113,334,124 - 113,343,984 (-)EnsemblGRCm38mm10GRCm38
MGSCv376113,284,118 - 113,293,916 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366113,299,901 - 113,309,699 (-)NCBIMGSCv36mm8
Celera6115,161,124 - 115,170,917 (-)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.75NCBI
Camk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555611,282,970 - 1,294,972 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555611,282,970 - 1,292,710 (-)NCBIChiLan1.0ChiLan1.0
CAMK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v229,768,303 - 9,780,976 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan139,773,061 - 9,785,734 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v039,708,782 - 9,721,433 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.139,947,275 - 9,959,560 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl39,945,609 - 9,959,560 (-)Ensemblpanpan1.1panPan2
CAMK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1208,475,902 - 8,486,214 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl208,475,716 - 8,486,214 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha208,508,977 - 8,519,292 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0208,505,194 - 8,515,504 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl208,505,011 - 8,517,090 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1208,227,664 - 8,237,979 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0208,572,188 - 8,582,503 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0208,545,805 - 8,556,117 (+)NCBIUU_Cfam_GSD_1.0
Camk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494215,496,367 - 15,507,235 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366023,401,005 - 3,414,935 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366023,402,559 - 3,413,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAMK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1366,044,720 - 66,055,295 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11366,044,713 - 66,055,290 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21373,092,176 - 73,102,714 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAMK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12245,763,799 - 45,776,792 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2245,762,499 - 45,774,597 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041120,790,539 - 120,803,686 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Camk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247314,383,927 - 4,399,369 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247314,388,373 - 4,399,762 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Camk1
16 total Variants

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:35
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000029728
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 58 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4116179486151161268Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat

1 to 10 of 58 rows
RH128087  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,480,937 - 146,481,139 (+)MAPPERmRatBN7.2
Rnor_6.04145,289,042 - 145,289,243NCBIRnor6.0
Rnor_5.04208,586,192 - 208,586,392UniSTSRnor5.0
Celera4135,038,254 - 135,038,455UniSTS
RH 3.4 Map4937.4UniSTS
Cytogenetic Map4q42UniSTS
AI505105  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,481,267 - 146,481,394 (+)MAPPERmRatBN7.2
Rnor_6.04145,289,372 - 145,289,498NCBIRnor6.0
Rnor_5.04208,586,521 - 208,586,647UniSTSRnor5.0
Celera4135,038,584 - 135,038,710UniSTS
Cytogenetic Map4q42UniSTS
D6Ertd263e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,481,234 - 146,481,453 (+)MAPPERmRatBN7.2
Rnor_6.04145,289,339 - 145,289,557NCBIRnor6.0
Rnor_5.04208,586,488 - 208,586,706UniSTSRnor5.0
Celera4135,038,551 - 135,038,769UniSTS
Cytogenetic Map4q42UniSTS
RH136941  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,481,737 - 146,481,926 (+)MAPPERmRatBN7.2
Rnor_6.04145,289,842 - 145,290,030NCBIRnor6.0
Rnor_5.04208,586,991 - 208,587,179UniSTSRnor5.0
Celera4135,039,054 - 135,039,242UniSTS
RH 3.4 Map4937.5UniSTS
Cytogenetic Map4q42UniSTS
RH137514  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24146,481,260 - 146,481,393 (+)MAPPERmRatBN7.2
Rnor_6.04145,289,365 - 145,289,497NCBIRnor6.0
Rnor_5.04208,586,514 - 208,586,646UniSTSRnor5.0
Celera4135,038,577 - 135,038,709UniSTS
Cytogenetic Map4q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000029728   ⟹   ENSRNOP00000033456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,481,196 - 146,492,081 (-)Ensembl
Rnor_6.0 Ensembl4145,288,996 - 145,300,177 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093950   ⟹   ENSRNOP00000091265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,481,199 - 146,491,517 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106794   ⟹   ENSRNOP00000096413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4146,481,196 - 146,488,887 (-)Ensembl
RefSeq Acc Id: NM_134468   ⟹   NP_604463
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,036,843 - 148,047,145 (-)NCBI
mRatBN7.24146,481,196 - 146,491,498 (-)NCBI
Rnor_6.04145,289,300 - 145,299,602 (-)NCBI
Rnor_5.04208,586,449 - 208,597,283 (-)NCBI
RGSC_v3.44149,220,661 - 149,229,168 (-)RGD
Celera4135,038,512 - 135,048,763 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237001   ⟹   XP_006237063
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,036,848 - 148,047,673 (-)NCBI
mRatBN7.24146,481,201 - 146,492,038 (-)NCBI
Rnor_6.04145,289,305 - 145,300,146 (-)NCBI
Rnor_5.04208,586,449 - 208,597,283 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106984   ⟹   XP_038962912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,036,848 - 148,047,674 (-)NCBI
mRatBN7.24146,481,201 - 146,492,039 (-)NCBI
RefSeq Acc Id: XM_039106985   ⟹   XP_038962913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,036,848 - 148,047,669 (-)NCBI
mRatBN7.24146,481,201 - 146,492,034 (-)NCBI
RefSeq Acc Id: XM_063285458   ⟹   XP_063141528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,036,848 - 148,047,675 (-)NCBI
RefSeq Acc Id: XM_063285459   ⟹   XP_063141529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84148,036,848 - 148,047,669 (-)NCBI
RefSeq Acc Id: NP_604463   ⟸   NM_134468
- UniProtKB: Q63084 (UniProtKB/Swiss-Prot),   Q63450 (UniProtKB/Swiss-Prot),   A6IBQ6 (UniProtKB/TrEMBL),   A0A8I6B458 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237063   ⟸   XM_006237001
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AEY2 (UniProtKB/TrEMBL),   A0A8I6B458 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033456   ⟸   ENSRNOT00000029728
RefSeq Acc Id: XP_038962912   ⟸   XM_039106984
- Peptide Label: isoform X1
- UniProtKB: A0A8I6B458 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962913   ⟸   XM_039106985
- Peptide Label: isoform X3
- UniProtKB: A0A8L2UL04 (UniProtKB/TrEMBL),   A0A8I6B458 (UniProtKB/TrEMBL)
Protein kinase

Name Modeler Protein Id AA Range Protein Structure
AF-Q63450-F1-model_v2 AlphaFold Q63450 1-374 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693296
Promoter ID:EPDNEW_R3820
Type:initiation region
Name:Camk1_1
Description:calcium/calmodulin-dependent protein kinase I
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04145,299,642 - 145,299,702EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-43394 BioCyc
Ensembl Genes ENSRNOG00000021781 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000029728 ENTREZGENE
  ENSRNOT00000093950 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7098592 IMAGE-MGC_LOAD
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
KEGG Report rno:171503 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91494 IMAGE-MGC_LOAD
NCBI Gene 171503 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Camk1 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000021781 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A0A8I6AEY2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B458 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UL04 ENTREZGENE, UniProtKB/TrEMBL
  A6IBQ6 ENTREZGENE, UniProtKB/TrEMBL
  KCC1A_RAT UniProtKB/Swiss-Prot
  Q63084 ENTREZGENE
  Q63450 ENTREZGENE
UniProt Secondary Q63084 UniProtKB/Swiss-Prot
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Camk1  calcium/calmodulin-dependent protein kinase I    regulator of G-protein signalling 19  Name updated 1299863 APPROVED
2003-04-06 Camk1  regulator of G-protein signalling 19      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_expression expressed in hippocampal neurons 625618