Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Phf1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PHF1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Phf1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PHF1 mRNA | CTD | PMID:22206623 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Phf1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | 2-hydroxypropanoic acid | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PHF1 mRNA | CTD | PMID:30851411 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PHF1 mRNA | CTD | PMID:28628672 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PHF1 mRNA | CTD | PMID:22504374 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PHF1 mRNA | CTD | PMID:30047161 | aflatoxin B1 | decreases methylation | ISO | PHF1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PHF1 gene | CTD | PMID:27153756 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of PHF1 mRNA | CTD | PMID:30047161 | arsenous acid | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PHF1 mRNA | CTD | PMID:25258189 | atrazine | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Atrazine results in increased expression of PHF1 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | Phf1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PHF1 mRNA | CTD | PMID:21715664 | benzo[a]pyrene | decreases methylation | ISO | PHF1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of PHF1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PHF1 mRNA | CTD | PMID:22316170 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PHF1 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Phf1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of PHF1 mRNA | CTD | PMID:33221593 | bisphenol A | affects methylation | ISO | Phf1 (Mus musculus) | 6480464 | bisphenol A affects the methylation of PHF1 promoter | CTD | PMID:27334623 | bisphenol F | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PHF1 mRNA | CTD | PMID:28628672 | bortezomib | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Bortezomib results in increased expression of PHF1 mRNA | CTD | PMID:20977926 | cadmium atom | multiple interactions | ISO | Phf1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PHF1 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Phf1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PHF1 mRNA | CTD | PMID:37325564 | caffeine | decreases phosphorylation | ISO | PHF1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of PHF1 protein | CTD | PMID:35688186 | calcitriol | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of PHF1 mRNA | CTD | PMID:21592394 | calcitriol | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of PHF1 mRNA | CTD | PMID:21592394 | carbon nanotube | decreases expression | ISO | Phf1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | clotrimazole | decreases expression | EXP | | 6480464 | Clotrimazole results in decreased expression of PHF1 mRNA | CTD | PMID:30047161 | cobalt dichloride | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of PHF1 mRNA | CTD | PMID:19320972 and PMID:19376846 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of PHF1 mRNA | CTD | PMID:24386269 | copper atom | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of PHF1 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of PHF1 mRNA | CTD | PMID:20971185 | CU-O LINKAGE | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | cupric oxide results in increased expression of PHF1 mRNA | CTD | PMID:22077320 | cyclosporin A | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PHF1 mRNA | CTD | PMID:20106945 more ... | dexamethasone | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PHF1 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PHF1 mRNA | CTD | PMID:25258189 | dorsomorphin | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF1 mRNA | CTD | PMID:27188386 | ethyl methanesulfonate | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of PHF1 mRNA | CTD | PMID:23649840 | formaldehyde | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of PHF1 mRNA | CTD | PMID:23649840 | FR900359 | affects phosphorylation | ISO | PHF1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of PHF1 protein | CTD | PMID:37730182 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PHF1 mRNA | CTD | PMID:33387578 | geraniol | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | geraniol results in increased expression of PHF1 mRNA | CTD | PMID:27683099 | indometacin | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of PHF1 mRNA | CTD | PMID:28628672 | lead(0) | affects expression | ISO | PHF1 (Homo sapiens) | 6480464 | Lead affects the expression of PHF1 mRNA | CTD | PMID:28903495 | linalool | decreases expression | ISO | PHF1 (Homo sapiens) | 6480464 | linalool results in decreased expression of PHF1 mRNA | CTD | PMID:27683099 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of PHF1 mRNA | CTD | PMID:22504374 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of PHF1 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PHF1 mRNA | CTD | PMID:23649840 | nickel atom | multiple interactions | EXP | | 6480464 | [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of PHF1 mRNA | CTD | PMID:31734292 | nickel sulfate | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of PHF1 mRNA | CTD | PMID:22714537 | nickel sulfate | multiple interactions | EXP | | 6480464 | [nickel sulfate results in increased abundance of Nickel] which results in decreased expression of PHF1 mRNA | CTD | PMID:31734292 | ozone | multiple interactions | ISO | Phf1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of PHF1 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Phf1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PHF1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PHF1 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Phf1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PHF1 mRNA | CTD | PMID:36331819 | rac-lactic acid | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Lactic Acid results in increased expression of PHF1 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF1 mRNA | CTD | PMID:27188386 | sevoflurane | increases expression | ISO | Phf1 (Mus musculus) | 6480464 | Sevoflurane results in increased expression of PHF1 protein | CTD | PMID:35575159 | sevoflurane | multiple interactions | ISO | Phf1 (Mus musculus) | 6480464 | APOE protein alternative form inhibits the reaction [Sevoflurane results in increased expression of PHF1 protein] | CTD | PMID:35575159 | silicon dioxide | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of PHF1 mRNA | CTD | PMID:25895662 | sodium arsenite | affects expression | ISO | PHF1 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of PHF1 mRNA | CTD | PMID:29319823 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of PHF1 mRNA | CTD | PMID:30047161 | testosterone | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of PHF1 mRNA | CTD | PMID:21592394 | testosterone | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Testosterone results in increased expression of PHF1 mRNA | CTD | PMID:21592394 | tetrachloromethane | affects expression | ISO | Phf1 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of PHF1 mRNA | CTD | PMID:17484886 | valproic acid | affects expression | ISO | PHF1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PHF1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | PHF1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF1 mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PHF1 mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | increases expression | ISO | PHF1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PHF1 mRNA | CTD | PMID:29154799 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of PHF1 mRNA | CTD | PMID:23034163 | vorinostat | decreases expression | ISO | PHF1 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of PHF1 mRNA | CTD | PMID:27188386 | |