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Gene: Macroh2a1 (macroH2A.1 histone) Rattus norvegicus
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Symbol: Macroh2a1
Name: macroH2A.1 histone
Description: Predicted to have several functions, including DNA binding activity; promoter-specific chromatin binding activity; and protein serine/threonine kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; regulation of gene expression, epigenetic; and regulation of response to oxidative stress. Localizes to the nucleosome and nucleus. Orthologous to human MACROH2A1 (macroH2A.1 histone); PARTICIPATES IN histone modification pathway; systemic lupus erythematosus pathway; INTERACTS WITH 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: core histone macro-H2A.1; H2A histone family, member Y; H2A.y; H2A/y; H2afy; histone macroH2A1; MGC105515; mH2A1
Orthologs:
Homo sapiens (human) : MACROH2A1 (macroH2A.1 histone)  HGNC  Alliance
Mus musculus (house mouse) : Macroh2a1 (macroH2A.1 histone)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102008188 (core histone macro-H2A.1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100974858 (core histone macro-H2A.1)
Canis lupus familiaris (dog) : MACROH2A1 (macroH2A.1 histone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101971629 (core histone macro-H2A.1)
Sus scrofa (pig) : H2AFY (H2A histone family, member Y)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0179,282,109 - 9,344,698 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,282,675 - 9,344,678 (+)Ensembl
Rnor_5.01711,440,567 - 11,502,758 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41714,457,307 - 14,520,963 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11714,457,306 - 14,520,963 (+)NCBI
Celera178,563,234 - 8,625,826 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Macroh2a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621462
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.