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Gene: Adam22 (ADAM metallopeptidase domain 22) Rattus norvegicus
Symbol: Adam22
Name: ADAM metallopeptidase domain 22
Description: Predicted to have metalloendopeptidase activity. Predicted to be involved in adult locomotory behavior; myelination in peripheral nervous system; and neurotransmitter receptor localization to postsynaptic specialization membrane. Predicted to localize to the axon; glutamatergic synapse; and integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 61. Orthologous to human ADAM22 (ADAM metallopeptidase domain 22); INTERACTS WITH bisphenol A; endosulfan; gentamycin.
Type: protein-coding
RefSeq Status: MODEL
Also known as: a disintegrin and metalloprotease domain (ADAM) 22; a disintegrin and metalloprotease domain (ADAM) 22 (mapped); a disintegrin and metalloprotease domain 22; Adam22_mapped; disintegrin and metalloproteinase domain-containing protein 22; LOC683655; MDC2; similar to ADAM 22 precursor (A disintegrin and metalloproteinase domain 22)
Homo sapiens (human) : ADAM22 (ADAM metallopeptidase domain 22)  HGNC  Alliance
Mus musculus (house mouse) : Adam22 (a disintegrin and metallopeptidase domain 22)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adam22 (ADAM metallopeptidase domain 22)
Pan paniscus (bonobo/pygmy chimpanzee) : ADAM22 (ADAM metallopeptidase domain 22)
Canis lupus familiaris (dog) : ADAM22 (ADAM metallopeptidase domain 22)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adam22 (ADAM metallopeptidase domain 22)
Sus scrofa (pig) : ADAM22 (ADAM metallopeptidase domain 22)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0422,864,485 - 23,002,969 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0422,873,544 - 22,935,588 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0422,632,816 - 22,827,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4422,332,086 - 22,507,086 (-)NCBIRGSC3.4rn4RGSC3.4
Celera421,356,458 - 21,453,378 (+)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Adam22
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1585016
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.