Adam22 (ADAM metallopeptidase domain 22) - Rat Genome Database

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Gene: Adam22 (ADAM metallopeptidase domain 22) Rattus norvegicus
Analyze
Symbol: Adam22
Name: ADAM metallopeptidase domain 22
RGD ID: 1585016
Description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in neurotransmitter receptor localization to postsynaptic specialization membrane. Predicted to act upstream of or within adult locomotory behavior and myelination in peripheral nervous system. Predicted to be located in axon and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in glutamatergic synapse. Predicted to be integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 61. Orthologous to human ADAM22 (ADAM metallopeptidase domain 22); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: a disintegrin and metalloprotease domain (ADAM) 22; a disintegrin and metalloprotease domain (ADAM) 22 (mapped); a disintegrin and metalloprotease domain 22; Adam22_mapped; disintegrin and metalloproteinase domain-containing protein 22; disintegrin and metalloproteinase domain-containing protein 22-like; LOC108350662; LOC683655; MDC2; similar to ADAM 22 precursor (A disintegrin and metalloproteinase domain 22)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2425,716,055 - 25,970,932 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl425,715,990 - 25,964,962 (+)Ensembl
Rnor_6.0422,864,485 - 23,002,969 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl422,859,622 - 22,996,645 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0422,873,544 - 22,935,588 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0422,632,816 - 22,827,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4422,332,086 - 22,507,086 (-)NCBIRGSC3.4rn4RGSC3.4
Celera421,356,458 - 21,453,378 (+)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:15876356   PMID:16990550   PMID:20089912   PMID:20133599   PMID:20220021   PMID:21068328   PMID:21700703   PMID:23525710   PMID:27066583   PMID:29358191   PMID:30598502  


Genomics

Comparative Map Data
Adam22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2425,716,055 - 25,970,932 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl425,715,990 - 25,964,962 (+)Ensembl
Rnor_6.0422,864,485 - 23,002,969 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl422,859,622 - 22,996,645 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0422,873,544 - 22,935,588 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0422,632,816 - 22,827,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4422,332,086 - 22,507,086 (-)NCBIRGSC3.4rn4RGSC3.4
Celera421,356,458 - 21,453,378 (+)NCBICelera
Cytogenetic Map4q12NCBI
ADAM22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl787,934,143 - 88,202,889 (+)EnsemblGRCh38hg38GRCh38
GRCh38787,934,163 - 88,202,889 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37787,563,566 - 87,832,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36787,401,638 - 87,664,390 (+)NCBINCBI36hg18NCBI36
Build 34787,208,352 - 87,471,098NCBI
Celera782,268,261 - 82,531,056 (+)NCBI
Cytogenetic Map7q21.12NCBI
HuRef782,173,445 - 82,442,057 (+)NCBIHuRef
CHM1_1787,493,737 - 87,762,729 (+)NCBICHM1_1
CRA_TCAGchr7v2786,894,883 - 87,163,561 (+)NCBI
Adam22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3958,122,347 - 8,418,312 (-)NCBIGRCm39mm39
GRCm39 Ensembl58,122,352 - 8,418,160 (-)Ensembl
GRCm3858,072,347 - 8,368,312 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl58,072,352 - 8,368,160 (-)EnsemblGRCm38mm10GRCm38
MGSCv3758,072,352 - 8,368,081 (-)NCBIGRCm37mm9NCBIm37
MGSCv3658,098,266 - 8,374,087 (-)NCBImm8
Celera58,005,837 - 8,298,614 (-)NCBICelera
Cytogenetic Map5A1NCBI
cM Map53.39NCBI
Adam22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554325,305,611 - 5,536,282 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554325,306,018 - 5,536,282 (+)NCBIChiLan1.0ChiLan1.0
ADAM22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1793,578,988 - 93,846,903 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl793,579,306 - 93,840,484 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0779,930,613 - 80,197,498 (+)NCBIMhudiblu_PPA_v0panPan3
ADAM22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11414,032,434 - 14,256,835 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1414,032,475 - 14,250,554 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1413,603,791 - 13,828,940 (+)NCBI
ROS_Cfam_1.01413,797,440 - 14,021,747 (+)NCBI
UMICH_Zoey_3.11414,001,060 - 14,231,713 (+)NCBI
UNSW_CanFamBas_1.01413,726,826 - 13,951,335 (+)NCBI
UU_Cfam_GSD_1.01414,012,429 - 14,236,782 (+)NCBI
Adam22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511827,048,939 - 27,263,377 (+)NCBI
SpeTri2.0NW_004936763738,051 - 952,435 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAM22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl968,252,704 - 68,487,619 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1968,253,023 - 68,490,327 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2974,687,666 - 74,925,672 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAM22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12160,753,344 - 60,999,283 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2160,759,980 - 60,998,600 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604243,076,021 - 43,348,892 (+)NCBIVero_WHO_p1.0
Adam22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248095,190,974 - 5,448,317 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D4Got302  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2425,727,841 - 25,728,107 (+)MAPPERmRatBN7.2
Rnor_6.0422,931,319 - 22,931,584NCBIRnor6.0
Rnor_6.0422,712,288 - 22,712,533NCBIRnor6.0
Rnor_5.0422,644,273 - 22,644,518UniSTSRnor5.0
Rnor_5.0422,866,183 - 22,866,448UniSTSRnor5.0
RGSC_v3.4422,495,335 - 22,495,600UniSTSRGSC3.4
Celera421,213,806 - 21,214,071UniSTS
Cytogenetic Map4 RGD
RH142562  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2425,839,092 - 25,839,324 (+)MAPPERmRatBN7.2
Rnor_6.0422,826,418 - 22,826,649NCBIRnor6.0
Rnor_5.0422,759,764 - 22,759,995UniSTSRnor5.0
RGSC_v3.4422,388,493 - 22,388,724UniSTSRGSC3.4
Celera421,323,301 - 21,323,532UniSTS
RH 3.4 Map4156.0UniSTS
RH137701  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2425,948,216 - 25,948,430 (+)MAPPERmRatBN7.2
Rnor_6.0422,979,966 - 22,980,179NCBIRnor6.0
Rnor_5.0422,912,585 - 22,912,798UniSTSRnor5.0
Celera421,430,668 - 21,430,881UniSTS
RH 3.4 Map4156.0UniSTS
RH137892  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2425,737,633 - 25,737,858 (+)MAPPERmRatBN7.2
Rnor_6.0422,721,516 - 22,721,740NCBIRnor6.0
Rnor_5.0422,653,501 - 22,653,725UniSTSRnor5.0
RGSC_v3.4422,485,585 - 22,485,809UniSTSRGSC3.4
Celera421,223,600 - 21,223,824UniSTS
RH 3.4 Map4169.4UniSTS
Adam22  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2425,897,112 - 25,897,445 (+)MAPPERmRatBN7.2
Rnor_6.0422,889,134 - 22,889,466NCBIRnor6.0
Rnor_5.0422,824,848 - 22,825,180UniSTSRnor5.0
Celera421,381,100 - 21,381,432UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42133334344463908Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)42271068534430484Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:477
Count of miRNA genes:86
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000068410, ENSRNOT00000070872, ENSRNOT00000071635, ENSRNOT00000071921, ENSRNOT00000072068, ENSRNOT00000073044, ENSRNOT00000073501, ENSRNOT00000073723, ENSRNOT00000074832, ENSRNOT00000074918
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 60 5 1
Low 24 23 8 10 8 8 10 14 30 38 11 8
Below cutoff 3 18 19 18 9 18 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_017592940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001837516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001843290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005503424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI029994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000068410   ⟹   ENSRNOP00000059289
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,716,044 - 25,964,962 (+)Ensembl
Rnor_6.0 Ensembl422,859,622 - 22,996,645 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000073501   ⟹   ENSRNOP00000064723
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,864,422 - 25,961,471 (+)Ensembl
Rnor_6.0 Ensembl422,859,622 - 22,996,645 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094468   ⟹   ENSRNOP00000093947
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,716,044 - 25,964,962 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099765   ⟹   ENSRNOP00000077847
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,716,122 - 25,964,962 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101856   ⟹   ENSRNOP00000094391
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,716,044 - 25,951,817 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108037   ⟹   ENSRNOP00000081703
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,716,044 - 25,964,962 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111685   ⟹   ENSRNOP00000094323
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,715,990 - 25,964,962 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114747   ⟹   ENSRNOP00000085571
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,715,990 - 25,964,962 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115124   ⟹   ENSRNOP00000081419
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl425,715,990 - 25,964,962 (+)Ensembl
RefSeq Acc Id: XM_039108561   ⟹   XP_038964489
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,056 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108562   ⟹   XP_038964490
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,055 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108563   ⟹   XP_038964491
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,056 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108564   ⟹   XP_038964492
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,056 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108565   ⟹   XP_038964493
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,056 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108566   ⟹   XP_038964494
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,056 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108567   ⟹   XP_038964495
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,057 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108568   ⟹   XP_038964496
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,058 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108569   ⟹   XP_038964497
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,057 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108570   ⟹   XP_038964498
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,059 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108571   ⟹   XP_038964499
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,058 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108572   ⟹   XP_038964500
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,059 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108573   ⟹   XP_038964501
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,058 - 25,970,932 (+)NCBI
RefSeq Acc Id: XM_039108574   ⟹   XP_038964502
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,058 - 25,951,265 (+)NCBI
RefSeq Acc Id: XR_005503424
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2425,716,057 - 25,961,372 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSRNOP00000064723   ⟸   ENSRNOT00000073501
RefSeq Acc Id: ENSRNOP00000059289   ⟸   ENSRNOT00000068410
RefSeq Acc Id: XP_038964490   ⟸   XM_039108562
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038964489   ⟸   XM_039108561
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038964492   ⟸   XM_039108564
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038964491   ⟸   XM_039108563
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038964493   ⟸   XM_039108565
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038964494   ⟸   XM_039108566
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038964495   ⟸   XM_039108567
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038964497   ⟸   XM_039108569
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038964496   ⟸   XM_039108568
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038964499   ⟸   XM_039108571
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038964501   ⟸   XM_039108573
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038964502   ⟸   XM_039108574
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038964498   ⟸   XM_039108570
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038964500   ⟸   XM_039108572
- Peptide Label: isoform X12
RefSeq Acc Id: ENSRNOP00000081419   ⟸   ENSRNOT00000115124
RefSeq Acc Id: ENSRNOP00000094391   ⟸   ENSRNOT00000101856
RefSeq Acc Id: ENSRNOP00000077847   ⟸   ENSRNOT00000099765
RefSeq Acc Id: ENSRNOP00000094323   ⟸   ENSRNOT00000111685
RefSeq Acc Id: ENSRNOP00000093947   ⟸   ENSRNOT00000094468
RefSeq Acc Id: ENSRNOP00000081703   ⟸   ENSRNOT00000108037
RefSeq Acc Id: ENSRNOP00000085571   ⟸   ENSRNOT00000114747
Protein Domains
Disintegrin   EGF-like   Peptidase M12B

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1585016 AgrOrtholog
Ensembl Genes ENSRNOG00000042478 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000059289 UniProtKB/TrEMBL
  ENSRNOP00000064723 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068410 UniProtKB/TrEMBL
  ENSRNOT00000073501 UniProtKB/TrEMBL
Gene3D-CATH 3.40.390.10 UniProtKB/TrEMBL
  4.10.70.10 UniProtKB/TrEMBL
InterPro ADAM_Cys-rich UniProtKB/TrEMBL
  Blood-coag_inhib_Disintegrin UniProtKB/TrEMBL
  Disintegrin_CS UniProtKB/TrEMBL
  Disintegrin_dom_sf UniProtKB/TrEMBL
  EG-like_dom UniProtKB/TrEMBL
  EGF_extracell UniProtKB/TrEMBL
  MetalloPept_cat_dom UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  Reprolysin_adamalysin UniProtKB/TrEMBL
NCBI Gene 57033 ENTREZGENE
Pfam ADAM_CR UniProtKB/TrEMBL
  Disintegrin UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
PhenoGen Adam22 PhenoGen
PRINTS DISINTEGRIN UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  DISINTEGRIN_1 UniProtKB/TrEMBL
  DISINTEGRIN_2 UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  DISIN UniProtKB/TrEMBL
Superfamily-SCOP Disintegrin UniProtKB/TrEMBL
UniProt F1M542_RAT UniProtKB/TrEMBL
  M0R5P8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Adam22  ADAM metallopeptidase domain 22  LOC108350662  disintegrin and metalloproteinase domain-containing protein 22-like  Data Merged 737654 PROVISIONAL
2016-08-02 LOC108350662  disintegrin and metalloproteinase domain-containing protein 22-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-04-17 Adam22  ADAM metallopeptidase domain 22  LOC683655  similar to ADAM 22 precursor (A disintegrin and metalloproteinase domain 22)  Data Merged 737654 PROVISIONAL
2012-07-13 Adam22  ADAM metallopeptidase domain 22  Adam22  a disintegrin and metalloprotease domain (ADAM) 22  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-10 Adam22  a disintegrin and metalloprotease domain (ADAM) 22  Adam22_mapped  a disintegrin and metalloprotease domain (ADAM) 22 (mapped)  Data Merged 737654 APPROVED
2006-11-19 Adam22_mapped  a disintegrin and metalloprotease domain (ADAM) 22(mapped)  Adam22  a disintegrin and metalloprotease domain (ADAM) 22  Symbol set to symbol_mapped, name set to name (mapped) 1582166 APPROVED
2006-11-19 Adam22  a disintegrin and metalloprotease domain (ADAM) 22      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC683655  similar to ADAM 22 precursor (A disintegrin and metalloproteinase domain 22)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Adam22  a disintegrin and metalloprotease domain (ADAM) 22      Symbol and Name status set to provisional 70820 PROVISIONAL