Nub1 (negative regulator of ubiquitin-like proteins 1) - Rat Genome Database

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Gene: Nub1 (negative regulator of ubiquitin-like proteins 1) Rattus norvegicus
Analyze
Symbol: Nub1
Name: negative regulator of ubiquitin-like proteins 1
RGD ID: 1359489
Description: Predicted to be involved in several processes, including positive regulation of proteasomal ubiquitin-dependent protein catabolic process; response to interferon-gamma; and response to tumor necrosis factor. Predicted to act upstream of or within proteasomal protein catabolic process. Predicted to be located in Lewy body; cytosol; and nuclear lumen. Orthologous to human NUB1 (negative regulator of ubiquitin like proteins 1); PARTICIPATES IN neddylation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BS4; NEDD8 ultimate buster 1; NEDD8 ultimate buster-1; NY-REN-18 antigen; NYREN18
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2410,442,917 - 10,473,689 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,442,917 - 10,473,694 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx415,589,502 - 15,619,758 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0411,409,700 - 11,439,956 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.049,761,499 - 9,791,741 (-)NCBIRnor_WKY
Rnor_6.046,950,870 - 6,981,400 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.046,964,480 - 6,994,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,820,488 - 5,850,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.145,820,488 - 5,850,809 (-)NCBI
Celera46,058,478 - 6,088,841 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression. Kito K, etal., J Biol Chem 2001 Jun 8;276(23):20603-9. Epub 2001 Mar 19.
3. Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Parry G and Estelle M, Semin Cell Dev Biol. 2004 Apr;15(2):221-9.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16707496   PMID:22965877  


Genomics

Comparative Map Data
Nub1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2410,442,917 - 10,473,689 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,442,917 - 10,473,694 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx415,589,502 - 15,619,758 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0411,409,700 - 11,439,956 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.049,761,499 - 9,791,741 (-)NCBIRnor_WKY
Rnor_6.046,950,870 - 6,981,400 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.046,964,480 - 6,994,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,820,488 - 5,850,809 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.145,820,488 - 5,850,809 (-)NCBI
Celera46,058,478 - 6,088,841 (-)NCBICelera
Cytogenetic Map4q11NCBI
NUB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387151,341,812 - 151,378,449 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl7151,341,772 - 151,378,449 (+)EnsemblGRCh38hg38GRCh38
GRCh377151,038,898 - 151,075,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,669,791 - 150,706,468 (+)NCBINCBI36Build 36hg18NCBI36
Celera7145,596,247 - 145,632,781 (+)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7144,850,514 - 144,887,070 (+)NCBIHuRef
CHM1_17151,047,250 - 151,083,821 (+)NCBICHM1_1
T2T-CHM13v2.07152,514,799 - 152,551,295 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27150,368,354 - 150,404,911 (+)NCBI
Nub1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39524,890,813 - 24,915,376 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl524,890,530 - 24,915,376 (+)EnsemblGRCm39 Ensembl
GRCm38524,685,815 - 24,710,378 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl524,685,532 - 24,710,378 (+)EnsemblGRCm38mm10GRCm38
MGSCv37524,191,633 - 24,216,373 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36524,196,041 - 24,220,443 (+)NCBIMGSCv36mm8
Celera521,642,444 - 21,667,264 (+)NCBICelera
Cytogenetic Map5A3NCBI
Nub1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,709,791 - 5,739,079 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,709,791 - 5,737,620 (+)NCBIChiLan1.0ChiLan1.0
NUB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17155,079,171 - 155,115,913 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7155,079,243 - 155,114,676 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07142,927,730 - 142,964,475 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
NUB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,355,237 - 15,382,284 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,352,476 - 15,381,095 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,962,876 - 15,989,492 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01617,077,383 - 17,104,127 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1617,075,097 - 17,104,127 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11615,449,341 - 15,475,957 (+)NCBIUMICH_Zoey_3.1
Nub1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,146,984 - 6,177,063 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365276,726,363 - 6,756,445 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl185,899,568 - 5,928,884 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1185,899,566 - 5,928,981 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,247,107 - 6,274,794 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,525,757 - 119,559,412 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,525,932 - 119,560,886 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607215,496,939 - 15,530,260 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nub1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248005,315,381 - 5,345,801 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248005,314,203 - 5,345,301 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
D4Rat144  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,495,201 - 10,495,445 (+)MAPPERmRatBN7.2
Rnor_6.047,023,217 - 7,023,460NCBIRnor6.0
Rnor_5.047,035,728 - 7,035,971UniSTSRnor5.0
RGSC_v3.445,874,672 - 5,874,916RGDRGSC3.4
RGSC_v3.445,874,673 - 5,874,916UniSTSRGSC3.4
RGSC_v3.145,874,588 - 5,874,945RGD
Celera46,111,278 - 6,111,521UniSTS
SHRSP x BN Map40.0UniSTS
SHRSP x BN Map40.0RGD
Cytogenetic Map4q11UniSTS
D4Got11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,447,700 - 10,447,806 (+)MAPPERmRatBN7.2
Rnor_6.046,955,148 - 6,955,253NCBIRnor6.0
Rnor_5.046,968,758 - 6,968,863UniSTSRnor5.0
RGSC_v3.445,824,766 - 5,824,871UniSTSRGSC3.4
RGSC_v3.445,825,097 - 5,825,203RGDRGSC3.4
RGSC_v3.445,824,765 - 5,824,871RGDRGSC3.4
RGSC_v3.445,825,098 - 5,825,203UniSTSRGSC3.4
RGSC_v3.145,825,098 - 5,825,203RGD
RH 3.4 Map414.0UniSTS
RH 3.4 Map414.0RGD
RH 2.0 Map463.2RGD
Cytogenetic Map4q11UniSTS
RH128463  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,019 - 10,443,209 (+)MAPPERmRatBN7.2
Rnor_6.046,950,467 - 6,950,656NCBIRnor6.0
Rnor_5.046,964,077 - 6,964,266UniSTSRnor5.0
RGSC_v3.445,820,085 - 5,820,274UniSTSRGSC3.4
Celera46,058,075 - 6,058,264UniSTS
Cytogenetic Map4q11UniSTS
RH128761  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,580 - 10,443,766 (+)MAPPERmRatBN7.2
Rnor_6.046,951,028 - 6,951,213NCBIRnor6.0
Rnor_5.046,964,638 - 6,964,823UniSTSRnor5.0
RGSC_v3.445,820,646 - 5,820,831UniSTSRGSC3.4
Celera46,058,636 - 6,058,821UniSTS
Cytogenetic Map4q11UniSTS
RH138616  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,448,936 - 10,449,117 (+)MAPPERmRatBN7.2
Rnor_6.046,956,381 - 6,956,561NCBIRnor6.0
Rnor_5.046,969,991 - 6,970,171UniSTSRnor5.0
RGSC_v3.445,826,331 - 5,826,511UniSTSRGSC3.4
Celera46,064,102 - 6,064,282UniSTS
Cytogenetic Map4q11UniSTS
RH139609  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2410,443,184 - 10,443,376 (+)MAPPERmRatBN7.2
Rnor_6.046,950,632 - 6,950,823NCBIRnor6.0
Rnor_5.046,964,242 - 6,964,433UniSTSRnor5.0
RGSC_v3.445,820,250 - 5,820,441UniSTSRGSC3.4
Celera46,058,240 - 6,058,431UniSTS
Cytogenetic Map4q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4127716890Rat
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4127716890Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4127716890Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:65
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000045311
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000045311   ⟹   ENSRNOP00000048314
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,444,031 - 10,473,694 (-)Ensembl
Rnor_6.0 Ensembl46,951,478 - 6,978,073 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098051   ⟹   ENSRNOP00000086699
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,442,917 - 10,471,056 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108045   ⟹   ENSRNOP00000078815
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,442,919 - 10,470,461 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115102   ⟹   ENSRNOP00000076727
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl410,442,917 - 10,472,315 (-)Ensembl
RefSeq Acc Id: NM_001013925   ⟹   NP_001013947
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2410,443,423 - 10,473,689 (-)NCBI
Rnor_6.046,950,870 - 6,981,400 (-)NCBI
Rnor_5.046,964,480 - 6,994,708 (-)NCBI
RGSC_v3.445,820,488 - 5,850,809 (-)RGD
Celera46,058,478 - 6,088,841 (-)RGD
Sequence:
RefSeq Acc Id: XM_039107214   ⟹   XP_038963142
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2410,442,917 - 10,473,681 (-)NCBI
RefSeq Acc Id: XM_039107215   ⟹   XP_038963143
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2410,442,917 - 10,463,139 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001013947   ⟸   NM_001013925
- UniProtKB: Q5XIT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000048314   ⟸   ENSRNOT00000045311
RefSeq Acc Id: XP_038963142   ⟸   XM_039107214
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963143   ⟸   XM_039107215
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000078815   ⟸   ENSRNOT00000108045
RefSeq Acc Id: ENSRNOP00000086699   ⟸   ENSRNOT00000098051
RefSeq Acc Id: ENSRNOP00000076727   ⟸   ENSRNOT00000115102
Protein Domains
UBA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7ES73-F1-model_v2 AlphaFold F7ES73 1-612 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359489 AgrOrtholog
BioCyc Gene G2FUF-46056 BioCyc
Ensembl Genes ENSRNOG00000009282 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000048314 ENTREZGENE
  ENSRNOP00000048314.4 UniProtKB/TrEMBL
  ENSRNOP00000076727.1 UniProtKB/TrEMBL
  ENSRNOP00000078815.1 UniProtKB/TrEMBL
  ENSRNOP00000086699 ENTREZGENE
  ENSRNOP00000086699.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045311 ENTREZGENE
  ENSRNOT00000045311.5 UniProtKB/TrEMBL
  ENSRNOT00000098051 ENTREZGENE
  ENSRNOT00000098051.1 UniProtKB/TrEMBL
  ENSRNOT00000108045.1 UniProtKB/TrEMBL
  ENSRNOT00000115102.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131376 IMAGE-MGC_LOAD
InterPro NUB1 UniProtKB/TrEMBL
  NUB1_ubiquitin-like_dom UniProtKB/TrEMBL
  TPR-like_helical_dom UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
KEGG Report rno:296731 UniProtKB/TrEMBL
MGC_CLONE MGC:94244 IMAGE-MGC_LOAD
NCBI Gene 296731 ENTREZGENE
PANTHER PTHR12948 UniProtKB/TrEMBL
Pfam UBA UniProtKB/TrEMBL
  Ubiquitin_5 UniProtKB/TrEMBL
PhenoGen Nub1 PhenoGen
PROSITE UBA UniProtKB/TrEMBL
SMART UBA UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  UBA_like UniProtKB/TrEMBL
UniProt A0A8I5Y4X4_RAT UniProtKB/TrEMBL
  A0A8I5ZLQ1_RAT UniProtKB/TrEMBL
  A0A8I6A4A9_RAT UniProtKB/TrEMBL
  F7ES73_RAT UniProtKB/TrEMBL
  Q5XIT4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Nub1  negative regulator of ubiquitin-like proteins 1  Nub1  NEDD8 ultimate buster-1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 Nub1  NEDD8 ultimate buster-1      Symbol and Name status set to provisional 70820 PROVISIONAL