 Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:737211 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PGAM1 mRNA | CTD | PMID:21802500 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PGAM1 protein | CTD | PMID:15822908 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:732574 | 6480464 | Tetrachlorodibenzodioxin affects the expression of PGAM1 mRNA | CTD | PMID:21570461 | 2,5-hexanedione | increases expression | EXP | | 6480464 | 2, 5-hexanedione results in increased expression of PGAM1 protein | CTD | PMID:19033394 | 2-methylcholine | affects expression | ISO | RGD:737211 | 6480464 | beta-methylcholine affects the expression of PGAM1 mRNA | CTD | PMID:21179406 | 3H-1,2-dithiole-3-thione | increases expression | EXP | | 6480464 | 1, 2-dithiol-3-thione results in increased expression of PGAM1 mRNA | CTD | PMID:19162173 | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PGAM1 mRNA | CTD | PMID:24780913 | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PGAM1 mRNA | CTD | PMID:16483693 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of PGAM1 mRNA | CTD | PMID:30779732 | ampicillin | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein | CTD | PMID:30545405 | arsenite(3-) | decreases expression | EXP | | 6480464 | arsenite results in decreased expression of PGAM1 protein | CTD | PMID:21344382 | atrazine | increases expression | ISO | RGD:737211 | 6480464 | Atrazine results in increased expression of PGAM1 mRNA | CTD | PMID:22378314 | Azaspiracid | increases expression | ISO | RGD:737211 | 6480464 | azaspiracid results in increased expression of PGAM1 mRNA | CTD | PMID:28939011 | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | benzo[a]pyrene | decreases expression | ISO | RGD:737211 | 6480464 | Benzo(a)pyrene results in decreased expression of PGAM1 mRNA | CTD | PMID:21802500 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of PGAM1 protein | CTD | PMID:16456883 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | Benzo(a)pyrene promotes the reaction [sodium arsenite results in increased expression of PGAM1 protein], sodium arsenite promotes the reaction [Benzo(a)pyrene results in increased expression of PGAM1 protein] | CTD | PMID:16456883 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:737211 | 6480464 | Diethylhexyl Phthalate results in decreased expression of PGAM1 mRNA | CTD | PMID:28412506 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PGAM1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:737211 | 6480464 | bisphenol A results in decreased expression of PGAM1 mRNA | CTD | PMID:29275510 | bisphenol A | affects expression | ISO | RGD:737211 | 6480464 | bisphenol A affects the expression of PGAM1 mRNA | CTD | PMID:30903817 | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of PGAM1 protein | CTD | PMID:28903499 | cadmium dichloride | increases expression | ISO | RGD:737211 | 6480464 | Cadmium Chloride results in increased expression of PGAM1 protein | CTD | PMID:24527689 | calycosin | increases expression | ISO | RGD:737211 | 6480464 | 7, 3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PGAM1 protein | CTD | PMID:24455688 | carbon nanotube | affects expression | ISO | RGD:737211 | 6480464 | Nanotubes, Carbon affects the expression of PGAM1 protein | CTD | PMID:22001959 | carbon nanotube | increases expression | ISO | RGD:732574 | 6480464 | Nanotubes, Carbon analog results in increased expression of PGAM1 mRNA, Nanotubes, Carbon results in increased expression of PGAM1 mRNA | CTD | PMID:25554681 | carbon nanotube | decreases expression | ISO | RGD:732574 | 6480464 | Nanotubes, Carbon analog results in decreased expression of PGAM1 mRNA | CTD | PMID:25620056 | carbon nanotube | affects expression | ISO | RGD:732574 | 6480464 | Nanotubes, Carbon affects the expression of PGAM1 protein | CTD | PMID:21135415 | chloropicrin | affects expression | ISO | RGD:737211 | 6480464 | chloropicrin affects the expression of PGAM1 mRNA | CTD | PMID:26352163 | chloropicrin | decreases expression | ISO | RGD:737211 | 6480464 | chloropicrin results in decreased expression of PGAM1 mRNA | CTD | PMID:28476498 | clobetasol | increases expression | ISO | RGD:732574 | 6480464 | Clobetasol results in increased expression of PGAM1 mRNA | CTD | PMID:27462272 | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PGAM1 mRNA | CTD | PMID:17602206 | copper atom | affects binding | ISO | RGD:737211 | 6480464 | PGAM1 protein binds to Copper | CTD | PMID:15359738 | copper(0) | affects binding | ISO | RGD:737211 | 6480464 | PGAM1 protein binds to Copper | CTD | PMID:15359738 | copper(II) chloride | increases expression | ISO | RGD:732574 | 6480464 | cupric chloride results in increased expression of PGAM1 protein | CTD | PMID:29617964 | copper(II) sulfate | decreases expression | ISO | RGD:737211 | 6480464 | Copper Sulfate results in decreased expression of PGAM1 mRNA | CTD | PMID:19549813 | dibutyl phthalate | decreases expression | ISO | RGD:732574 | 6480464 | Dibutyl Phthalate results in decreased expression of PGAM1 mRNA | CTD | PMID:17361019, PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PGAM1 mRNA | CTD | PMID:17379624, PMID:21266533 | dioxygen | increases expression | ISO | RGD:732574 | 6480464 | Oxygen deficiency results in increased expression of PGAM1 mRNA | CTD | PMID:20880076 | enzyme inhibitor | multiple interactions | ISO | RGD:737211 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PGAM1 protein | CTD | PMID:23301498 | ethanol | increases expression | ISO | RGD:732574 | 6480464 | Ethanol results in increased expression of PGAM1 mRNA | CTD | PMID:19167417 | ethanol | multiple interactions | ISO | RGD:732574 | 6480464 | Ethanol affects the expression of and affects the splicing of PGAM1 mRNA | CTD | PMID:30319688 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of PGAM1 mRNA | CTD | PMID:15353170 | flavonoids | increases expression | EXP | | 6480464 | Flavonoids results in increased expression of PGAM1 mRNA | CTD | PMID:18035473 | fluoranthene | multiple interactions | ISO | RGD:732574 | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of PGAM1 mRNA | CTD | PMID:28329830 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of PGAM1 mRNA, Flutamide results in increased expression of PGAM1 protein | CTD | PMID:17311803, PMID:24136188 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PGAM1 mRNA | CTD | PMID:22061828 | gentamycin | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein | CTD | PMID:30545405 | hyaluronic acid | multiple interactions | EXP | | 6480464 | Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PGAM1 protein] | CTD | PMID:23178681 | hydrogen peroxide | multiple interactions | EXP | | 6480464 | Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PGAM1 protein] | CTD | PMID:23178681 | hydrogen peroxide | decreases expression | EXP | | 6480464 | Hydrogen Peroxide results in decreased expression of PGAM1 protein | CTD | PMID:23178681 | ibuprofen | affects expression | ISO | RGD:737211 | 6480464 | Ibuprofen affects the expression of PGAM1 protein | CTD | PMID:18351690 | ibuprofen | increases expression | ISO | RGD:737211 | 6480464 | Ibuprofen results in increased expression of PGAM1 mRNA | CTD | PMID:18351690 | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | lead(0) | decreases expression | ISO | RGD:737211 | 6480464 | Lead results in decreased expression of PGAM1 mRNA | CTD | PMID:19921347 | lead(2+) | decreases expression | ISO | RGD:737211 | 6480464 | Lead results in decreased expression of PGAM1 mRNA | CTD | PMID:19921347 | lithium atom | increases expression | EXP | | 6480464 | Lithium results in increased expression of PGAM1 protein | CTD | PMID:18296634 | lithium hydride | increases expression | EXP | | 6480464 | Lithium results in increased expression of PGAM1 protein | CTD | PMID:18296634 | lovastatin | decreases expression | ISO | RGD:732574 | 6480464 | Lovastatin results in decreased expression of PGAM1 mRNA | CTD | PMID:20493250 | lovastatin | increases expression | ISO | RGD:732574 | 6480464 | Lovastatin results in increased expression of PGAM1 mRNA | CTD | PMID:20493250 | methamphetamine | multiple interactions | ISO | RGD:732574 | 6480464 | (1R-(exo, exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of PGAM1 mRNA] | CTD | PMID:11756511 | methamphetamine | decreases expression | ISO | RGD:732574 | 6480464 | Methamphetamine results in decreased expression of PGAM1 mRNA | CTD | PMID:11756511 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of PGAM1 mRNA | CTD | PMID:28903497 | methotrexate | decreases expression | ISO | RGD:737211 | 6480464 | Methotrexate results in decreased expression of PGAM1 mRNA, Methotrexate results in decreased expression of PGAM1 protein | CTD | PMID:24736981 | methyl methanesulfonate | decreases expression | ISO | RGD:737211 | 6480464 | Methyl Methanesulfonate results in decreased expression of PGAM1 mRNA | CTD | PMID:23649840 | metronidazole | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein | CTD | PMID:30545405 | miconazole | increases expression | ISO | RGD:732574 | 6480464 | Miconazole results in increased expression of PGAM1 mRNA | CTD | PMID:27462272 | microcystin RR | decreases expression | ISO | RGD:737211 | 6480464 | microcystin RR results in decreased expression of PGAM1 protein | CTD | PMID:19111056 | monosodium L-glutamate | multiple interactions | ISO | RGD:732574 | 6480464 | [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of PGAM1 mRNA | CTD | PMID:22078008 | N-methyl-4-phenylpyridinium | decreases expression | ISO | RGD:732574 | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of PGAM1 mRNA | CTD | PMID:17475336, PMID:22776087 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PGAM1 mRNA more ... | CTD | PMID:17602206, PMID:25374375 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of PGAM1 mRNA | CTD | PMID:24136188 | neomycin | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein | CTD | PMID:30545405 | okadaic acid | multiple interactions | ISO | RGD:737211 | 6480464 | [Okadaic Acid co-treated with gambierol] results in decreased expression of PGAM1 protein | CTD | PMID:19397276 | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of PGAM1 mRNA | CTD | PMID:25838073 | paracetamol | affects expression | ISO | RGD:732574 | 6480464 | Acetaminophen affects the expression of PGAM1 mRNA | CTD | PMID:17562736 | paracetamol | multiple interactions | ISO | RGD:732574 | 6480464 | [CTH gene mutant form results in increased susceptibility to Acetaminophen] which results in decreased expression of PGAM1 protein | CTD | PMID:25499718 | paraquat | increases expression | ISO | RGD:732574 | 6480464 | Paraquat results in increased expression of PGAM1 mRNA, Paraquat results in increased expression of PGAM1 protein | CTD | PMID:27111068 | phenobarbital | affects expression | ISO | RGD:737211 | 6480464 | Phenobarbital affects the expression of PGAM1 mRNA | CTD | PMID:19159669 | phenobarbital | increases expression | ISO | RGD:732574 | 6480464 | Phenobarbital results in increased expression of PGAM1 mRNA | CTD | PMID:31836555 | phenobarbital | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased methylation of PGAM1 promoter, [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of PGAM1 mRNA | CTD | PMID:25374375 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of PGAM1 mRNA | CTD | PMID:19162173 | picrotoxin | decreases expression | EXP | | 6480464 | Picrotoxin results in decreased expression of PGAM1 mRNA | CTD | PMID:15170462 | pirinixic acid | increases expression | ISO | RGD:732574 | 6480464 | pirinixic acid results in increased expression of PGAM1 mRNA | CTD | PMID:18301758 | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | potassium chromate | increases expression | ISO | RGD:737211 | 6480464 | potassium chromate(VI) results in increased expression of PGAM1 mRNA | CTD | PMID:22714537 | promethazine | increases expression | EXP | | 6480464 | Promethazine results in increased expression of PGAM1 mRNA | CTD | PMID:28903497 | pterostilbene | decreases expression | ISO | RGD:737211 | 6480464 | pterostilbene results in decreased expression of PGAM1 protein | CTD | PMID:24936659 | quercetin | increases expression | ISO | RGD:737211 | 6480464 | Quercetin results in increased expression of PGAM1 protein | CTD | PMID:17292933 | resveratrol | decreases expression | ISO | RGD:737211 | 6480464 | resveratrol results in decreased expression of PGAM1 mRNA, resveratrol results in decreased expression of PGAM1 protein | CTD | PMID:15582268, PMID:16979140 | scopolamine | decreases expression | EXP | | 6480464 | Scopolamine results in decreased expression of PGAM1 mRNA | CTD | PMID:12818353 | silicon dioxide | increases secretion | ISO | RGD:737211 | 6480464 | Silicon Dioxide analog results in increased secretion of PGAM1 protein | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | RGD:737211 | 6480464 | sodium arsenite results in increased expression of PGAM1 mRNA, sodium arsenite results in increased expression of PGAM1 protein | CTD | PMID:15899475, PMID:28595984 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of PGAM1 protein | CTD | PMID:29459688 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of PGAM1 protein | CTD | PMID:16456883 | sodium arsenite | multiple interactions | EXP | | 6480464 | Benzo(a)pyrene promotes the reaction [sodium arsenite results in increased expression of PGAM1 protein], sodium arsenite promotes the reaction [Benzo(a)pyrene results in increased expression of PGAM1 protein] | CTD | PMID:16456883 | sulindac sulfide | decreases expression | ISO | RGD:737211 | 6480464 | sulindac sulfide results in decreased expression of PGAM1 mRNA | CTD | PMID:12734198 | T-2 Toxin | affects expression | EXP | | 6480464 | T-2 Toxin affects the expression of PGAM1 protein | CTD | PMID:26141394 | thapsigargin | decreases expression | ISO | RGD:737211 | 6480464 | Thapsigargin results in decreased expression of PGAM1 mRNA | CTD | PMID:22378314 | thimerosal | decreases expression | ISO | RGD:737211 | 6480464 | Thimerosal results in decreased expression of PGAM1 mRNA | CTD | PMID:27188386 | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of PGAM1 mRNA | CTD | PMID:19483382 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PGAM1 mRNA | CTD | PMID:28903497 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PGAM1 mRNA | CTD | PMID:19448997 | trimellitic anhydride | increases expression | ISO | RGD:732574 | 6480464 | trimellitic anhydride results in increased expression of PGAM1 mRNA | CTD | PMID:19042947 | tunicamycin | decreases expression | ISO | RGD:737211 | 6480464 | Tunicamycin results in decreased expression of PGAM1 mRNA | CTD | PMID:22378314, PMID:29453283 | vancomycin | multiple interactions | EXP | | 6480464 | [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in increased expression of PGAM1 protein | CTD | PMID:30545405 | warfarin | decreases expression | ISO | RGD:732574 | 6480464 | Warfarin results in decreased expression of PGAM1 mRNA | CTD | PMID:20493250 | warfarin | increases expression | ISO | RGD:732574 | 6480464 | Warfarin results in increased expression of PGAM1 mRNA | CTD | PMID:20493250 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsBiological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations
