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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcna3
Name: potassium voltage-gated channel subfamily A member 3
Acc ID: CHEBI:4754
Term: econazole
Definition: A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.
Chemical ID: MESH:D004464
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcna3decreases activityISOKCNA3 (Homo sapiens)6480464CTDEconazole results in decreased activity of KCNA3 proteinPMID:21362439
Kcna3multiple interactionsISOKCNA3 (Homo sapiens)6480464CTD[Econazole results in decreased activity of KCNA3 protein] which results in decreased import of ThalliumPMID:21362439
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