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Gene: Ptprz1 (protein tyrosine phosphatase, receptor type Z1) Rattus norvegicus
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Symbol: Ptprz1
Name: protein tyrosine phosphatase, receptor type Z1
Description: Exhibits fibroblast growth factor binding activity and protein tyrosine phosphatase activity. Involved in several processes, including hippocampus development; neurogenesis; and visual learning. Localizes to several cellular components, including integral component of postsynaptic density membrane; perineuronal net; and ruffle membrane. Biomarker of amyotrophic lateral sclerosis; middle cerebral artery infarction; status epilepticus; temporal lobe epilepsy; and visual epilepsy. Orthologous to human PTPRZ1 (protein tyrosine phosphatase receptor type Z1); INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; 6B4 proteoglycan; phosphacan; Protein tyrosine phosphatase receptor-type zeta polypeptide; protein tyrosine phosphatase, receptor-type, Z polypeptide 1; Protein tyrosine phosphatase, receptor-type, zeta polypeptide; PTP zeta; Ptpz; PTPzeta-A; PTPzeta-B; PTPzeta-S; R-PTP-zeta; receptor-type tyrosine-protein phosphatase zeta; RPTPbeta
Orthologs:
Homo sapiens (human) : PTPRZ1 (protein tyrosine phosphatase receptor type Z1)  HGNC  Alliance
Mus musculus (house mouse) : Ptprz1 (protein tyrosine phosphatase, receptor type Z, polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprz1 (protein tyrosine phosphatase receptor type Z1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRZ1 (protein tyrosine phosphatase receptor type Z1)
Canis lupus familiaris (dog) : PTPRZ1 (protein tyrosine phosphatase receptor type Z1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprz1 (protein tyrosine phosphatase receptor type Z1)
Sus scrofa (pig) : PTPRZ1 (protein tyrosine phosphatase receptor type Z1)
Chlorocebus sabaeus (African green monkey) : PTPRZ1 (protein tyrosine phosphatase receptor type Z1)
Heterocephalus glaber (naked mole-rat) : Ptprz1 (protein tyrosine phosphatase receptor type Z1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0449,941,046 - 50,140,764 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl449,941,304 - 50,140,762 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0449,730,302 - 49,927,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4449,267,521 - 49,468,692 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1449,498,094 - 49,699,266 (+)NCBI
Celera446,598,237 - 46,787,500 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ptprz1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3455
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.