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Gene: Gabbr1 (gamma-aminobutyric acid type B receptor subunit 1) Rattus norvegicus
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Symbol: Gabbr1
Name: gamma-aminobutyric acid type B receptor subunit 1
Description: Exhibits several functions, including G protein-coupled GABA receptor activity; extracellular matrix protein binding activity; and transcription factor binding activity. Involved in several processes, including neuron-glial cell signaling; positive regulation of growth hormone secretion; and regulation of amine transport. Localizes to several cellular components, including the cytoplasm; integral component of synaptic membrane; and neuron projection. Used to study visual epilepsy. Biomarker of hypertension and visual epilepsy. Orthologous to human GABBR1 (gamma-aminobutyric acid type B receptor subunit 1); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; gamma-aminobutyric acid (GABA) B receptor 1; gamma-aminobutyric acid (GABA) B receptor, 1; gb1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0201,955,344 - 1,984,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0203,996,333 - 4,025,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,553,297 - 1,582,426 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1201,554,603 - 1,577,774 (-)NCBI
Celera202,173,047 - 2,202,332 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gabbr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621537
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.