Gabbr1 (gamma-aminobutyric acid type B receptor subunit 1) - Rat Genome Database

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Gene: Gabbr1 (gamma-aminobutyric acid type B receptor subunit 1) Rattus norvegicus
Analyze
Symbol: Gabbr1
Name: gamma-aminobutyric acid type B receptor subunit 1
RGD ID: 621537
Description: Enables G protein-coupled GABA receptor activity; extracellular matrix protein binding activity; and protein heterodimerization activity. Involved in several processes, including negative regulation of adenylate cyclase activity; neuron-glial cell signaling; and regulation of secretion. Acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Located in several cellular components, including GABA-ergic synapse; axolemma; and dendrite. Is integral component of plasma membrane. Part of GABA receptor complex. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Used to study visual epilepsy. Biomarker of hypertension and visual epilepsy. Orthologous to human GABBR1 (gamma-aminobutyric acid type B receptor subunit 1); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; gamma-aminobutyric acid (GABA) B receptor 1; gamma-aminobutyric acid (GABA) B receptor, 1; gb1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2201,464,534 - 1,494,114 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl201,464,534 - 1,493,994 (-)Ensembl
Rnor_6.0201,955,344 - 1,984,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,955,359 - 1,984,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0203,996,333 - 4,025,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,553,297 - 1,582,426 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1201,554,603 - 1,577,774 (-)NCBI
Celera202,173,047 - 2,202,332 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2,2-trifluoroethanol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dinitrotoluene  (EXP)
3,3-diphenyl-N-(1-phenylethyl)-1-propanamine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
baclofen  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP)
cadmium dichloride  (EXP)
calcidiol  (EXP)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
chaetocin  (EXP)
chloral hydrate  (ISO)
Chloralose  (ISO)
chlorobutanol  (ISO)
choline  (EXP)
clozapine  (ISO)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
decabromodiphenyl ether  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazepam  (EXP)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enflurane  (ISO)
ethanol  (ISO)
ether  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
fenvalerate  (EXP)
gabapentin  (ISO)
gamma-aminobutyric acid  (EXP,ISO)
glyphosate  (EXP)
hexachlorophene  (ISO)
isoflurane  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
linalool  (EXP)
methoxyflurane  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
phencyclidine  (ISO)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
progesterone  (ISO)
SB 431542  (ISO)
scopolamine  (EXP)
sevoflurane  (ISO)
T-2 toxin  (EXP)
tebufenpyrad  (ISO)
tert-butanol  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tribromoethanol  (ISO)
trichloroethene  (ISO)
trifluoperazine  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
1. Bailey SJ, etal., Neuropharmacology. 2004 Jan;46(1):31-42.
2. Bao XM, etal., Di Yi Jun Yi Da Xue Xue Bao 2002 Nov;22(11):961-5.
3. Barbaresi P J Comp Neurol. 2007 Dec 10;505(5):478-92.
4. Blein S, etal., J Biol Chem. 2004 Nov 12;279(46):48292-306. Epub 2004 Aug 9.
5. Chen L, etal., J Biomed Sci. 2004 Jul-Aug;11(4):457-64.
6. Chronwall BM, etal., J Neurochem 2001 Jun;77(5):1237-47.
7. Comps-Agrar L, etal., EMBO J. 2011 May 6;30(12):2336-49. doi: 10.1038/emboj.2011.143.
8. Cunningham MD and Enna SJ, Brain Res. 1996 May 13;720(1-2):220-4.
9. Fadda P, etal., Synapse. 2003 Oct;50(1):1-6.
10. Fujimori S, etal., Biochem Biophys Res Commun 2002 May 24;293(5):1445-52.
11. Gamel-Didelon K, etal., Neuroendocrinology. 2002 Sep;76(3):170-7.
12. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
13. GOA data from the GO Consortium
14. Harte M and O'Connor WT, Neuroscience. 2005;130(1):215-22.
15. Huo JZ, etal., Epilepsia. 2009 Apr;50(4):776-88.
16. Isomoto S, etal., Biochem Biophys Res Commun 1998 Dec 9;253(1):10-5.
17. Kang J, etal., Nat Neurosci. 1998 Dec;1(8):683-92. doi: 10.1038/3684.
18. Kantamneni S, etal., J Neurochem. 2007 Feb;100(4):1003-17. Epub 2007 Jan 4.
19. Kaupmann K, etal., Nature 1997 Mar 20;386(6622):239-46.
20. Kulik A, etal., Eur J Neurosci 2002 Jan;15(2):291-307.
21. Kulik A, etal., J Neurosci. 2003 Dec 3;23(35):11026-35.
22. Li SP, etal., Brain Res. 2005 Nov 2;1061(1):27-35. Epub 2005 Oct 24.
23. Li SP, etal., Neurosci Lett 2002 Dec 13;334(2):135-9.
24. Li SP, etal., Synapse. 2006 Dec 15;60(8):557-66.
25. Magnaghi V, etal., Eur J Neurosci. 2004 May;19(10):2641-9.
26. Martin P, etal., Neuropsychobiology. 1988;19(3):146-8.
27. MGD data from the GO Consortium
28. Min MY, etal., J Biomed Sci 2002 Jul-Aug;9(4):348-58.
29. Monnier C, etal., EMBO J. 2011 Jan 5;30(1):32-42. doi: 10.1038/emboj.2010.270. Epub 2010 Nov 9.
30. NCBI rat LocusLink and RefSeq merged data July 26, 2002
31. Nehring RB, etal., J Biol Chem 2000 Nov 10;275(45):35185-91.
32. Pfaff T, etal., Eur J Neurosci 1999 Aug;11(8):2874-82.
33. RGD automated data pipeline
34. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
35. RGD automated import pipeline for gene-chemical interactions
36. Rives ML, etal., EMBO J. 2009 Aug 5;28(15):2195-208. doi: 10.1038/emboj.2009.177. Epub 2009 Jul 9.
37. Spary EJ, etal., J Mol Neurosci. 2008 Jun;35(2):211-24. Epub 2008 Mar 13.
38. Tiao JY, etal., J Biol Chem. 2008 Nov 7;283(45):31005-11. doi: 10.1074/jbc.M804464200. Epub 2008 Sep 2.
39. Ushigome A, etal., Neurochem Int. 2004 Feb;44(3):139-44.
40. Vidal RL, etal., J Cell Biochem. 2008 Feb 15;103(3):886-95.
41. Wei K, etal., Brain Res Mol Brain Res 2001 Apr 18;89(1-2):103-10.
42. Wei K, etal., Neuroreport 2001 Mar 26;12(4):833-7.
43. Yang K, etal., Biochem Biophys Res Commun. 2003 Mar 7;302(2):233-7.
Additional References at PubMed
PMID:9872316   PMID:9872744   PMID:10075644   PMID:10328880   PMID:10658574   PMID:10692480   PMID:11498050   PMID:12527730   PMID:12535164   PMID:12649368   PMID:12711093   PMID:12763580  
PMID:12815184   PMID:12832501   PMID:12861336   PMID:12917685   PMID:12948615   PMID:14503843   PMID:15013631   PMID:15019566   PMID:15173634   PMID:15176083   PMID:15482257   PMID:15946159  
PMID:15978014   PMID:16037405   PMID:16096337   PMID:16297450   PMID:16343781   PMID:16408749   PMID:16436607   PMID:16472824   PMID:16624949   PMID:16724110   PMID:16938274   PMID:17044980  
PMID:17207629   PMID:17215590   PMID:17218355   PMID:17540011   PMID:17561812   PMID:18032562   PMID:18096145   PMID:18407377   PMID:18424635   PMID:18435423   PMID:18615498   PMID:18948198  
PMID:19052921   PMID:19211975   PMID:19229613   PMID:19328818   PMID:19640481   PMID:20400944   PMID:20643921   PMID:20643948   PMID:20826795   PMID:21144999   PMID:21184807   PMID:21212011  
PMID:21290407   PMID:21618582   PMID:21664264   PMID:21980366   PMID:22120979   PMID:22169202   PMID:22363012   PMID:22692127   PMID:22727822   PMID:22761875   PMID:22871113   PMID:23192081  
PMID:23401614   PMID:23508979   PMID:23803332   PMID:23829864   PMID:24020808   PMID:24114844   PMID:24425870   PMID:24668805   PMID:25429759   PMID:25706125   PMID:25864813   PMID:26403151  
PMID:26699387   PMID:27118845   PMID:27573246   PMID:28009293   PMID:28450542   PMID:32651311   PMID:32717394  


Genomics

Comparative Map Data
Gabbr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2201,464,534 - 1,494,114 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl201,464,534 - 1,493,994 (-)Ensembl
Rnor_6.0201,955,344 - 1,984,907 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,955,359 - 1,984,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0203,996,333 - 4,025,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4201,553,297 - 1,582,426 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1201,554,603 - 1,577,774 (-)NCBI
Celera202,173,047 - 2,202,332 (-)NCBICelera
Cytogenetic Map20p12NCBI
GABBR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl629,555,629 - 29,633,976 (-)EnsemblGRCh38hg38GRCh38
GRCh38629,602,230 - 29,633,183 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37629,570,015 - 29,600,960 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,677,984 - 29,708,839 (-)NCBINCBI36hg18NCBI36
Build 34629,677,984 - 29,708,839NCBI
Celera631,176,094 - 31,207,052 (-)NCBI
Cytogenetic Map6p22.1NCBI
HuRef629,377,091 - 29,408,050 (-)NCBIHuRef
CHM1_1629,572,149 - 29,603,041 (-)NCBICHM1_1
Gabbr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,356,858 - 37,385,197 (+)NCBIGRCm39mm39
GRCm39 Ensembl1737,356,858 - 37,385,959 (+)Ensembl
GRCm381737,045,966 - 37,074,305 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,045,966 - 37,075,067 (+)EnsemblGRCm38mm10GRCm38
MGSCv371737,182,911 - 37,211,250 (+)NCBIGRCm37mm9NCBIm37
MGSCv361736,654,124 - 36,682,342 (+)NCBImm8
Celera1740,469,514 - 40,497,873 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
Gabbr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495558385,255 - 115,189 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495558385,255 - 115,140 (-)NCBIChiLan1.0ChiLan1.0
GABBR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1630,065,119 - 30,095,663 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl630,065,119 - 30,095,304 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0629,405,026 - 29,437,108 (-)NCBIMhudiblu_PPA_v0panPan3
GABBR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13526,212,274 - 26,243,910 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3526,213,076 - 26,237,572 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3526,026,852 - 26,036,580 (-)NCBI
ROS_Cfam_1.03526,519,961 - 26,546,313 (-)NCBI
UMICH_Zoey_3.13526,175,827 - 26,201,883 (-)NCBI
UNSW_CanFamBas_1.03526,235,461 - 26,261,547 (-)NCBI
UU_Cfam_GSD_1.03527,705,638 - 27,731,798 (-)NCBI
Gabbr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494632,454,274 - 32,483,774 (-)NCBI
SpeTri2.0NW_0049367231,108,105 - 1,137,602 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABBR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl722,540,379 - 22,579,121 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1722,547,938 - 22,577,639 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2725,210,392 - 25,239,486 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GABBR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11742,985,816 - 43,017,278 (+)NCBI
ChlSab1.1 Ensembl1742,986,513 - 43,014,577 (+)Ensembl
Vero_WHO_p1.0NW_02366604429,132,753 - 29,162,814 (-)NCBI
Gabbr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475425,425,208 - 25,452,600 (+)NCBI

Position Markers
D20Wox20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,486,171 - 1,486,366 (+)MAPPERmRatBN7.2
Rnor_6.0201,976,981 - 1,977,175NCBIRnor6.0
Rnor_5.0204,017,606 - 4,017,800UniSTSRnor5.0
RGSC_v3.4201,574,604 - 1,574,798UniSTSRGSC3.4
Celera202,194,504 - 2,194,698UniSTS
Cytogenetic Map20p12UniSTS
RH133825  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,490,813 - 1,491,014 (+)MAPPERmRatBN7.2
Rnor_6.0201,981,623 - 1,981,823NCBIRnor6.0
Rnor_5.0204,022,248 - 4,022,448UniSTSRnor5.0
RGSC_v3.4201,579,247 - 1,579,447UniSTSRGSC3.4
Celera202,199,153 - 2,199,353UniSTS
RH 3.4 Map201.5UniSTS
Cytogenetic Map20p12UniSTS
RH136700  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,492,138 - 1,492,269 (+)MAPPERmRatBN7.2
Rnor_6.0201,982,947 - 1,983,077NCBIRnor6.0
Rnor_5.0204,023,572 - 4,023,702UniSTSRnor5.0
RGSC_v3.4201,580,571 - 1,580,701UniSTSRGSC3.4
Celera202,200,477 - 2,200,607UniSTS
Cytogenetic Map20p12UniSTS
RH138703  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,468,689 - 1,468,845 (+)MAPPERmRatBN7.2
Rnor_6.0201,959,500 - 1,959,655NCBIRnor6.0
Rnor_5.0204,000,489 - 4,000,644UniSTSRnor5.0
RGSC_v3.4201,557,453 - 1,557,608UniSTSRGSC3.4
Celera202,177,197 - 2,177,352UniSTS
RH 3.4 Map201.8UniSTS
Cytogenetic Map20p12UniSTS
UniSTS:496042  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2201,466,624 - 1,466,728 (+)MAPPERmRatBN7.2
Rnor_6.0201,957,435 - 1,957,538NCBIRnor6.0
Rnor_5.0203,998,424 - 3,998,527UniSTSRnor5.0
RGSC_v3.4201,555,388 - 1,555,491UniSTSRGSC3.4
Celera202,175,132 - 2,175,235UniSTS
Cytogenetic Map20p12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:475
Count of miRNA genes:216
Interacting mature miRNAs:248
Transcripts:ENSRNOT00000040232, ENSRNOT00000051634
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 30 12 4 12 4 74 22 33 11
Low 1 13 45 37 7 37 8 11 13 8 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006255879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005497343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB016160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB016161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC108572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF283276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF312319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF542081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ831471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ831472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM418837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX883052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000040232   ⟹   ENSRNOP00000047788
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,558 - 1,493,439 (-)Ensembl
Rnor_6.0 Ensembl201,955,368 - 1,984,737 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000051634   ⟹   ENSRNOP00000047498
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,534 - 1,493,994 (-)Ensembl
Rnor_6.0 Ensembl201,955,359 - 1,984,774 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078531
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,979,804 - 1,984,247 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079445   ⟹   ENSRNOP00000074507
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,981,436 - 1,984,802 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082545   ⟹   ENSRNOP00000075630
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,956,651 - 1,980,150 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084582   ⟹   ENSRNOP00000075610
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,534 - 1,493,439 (-)Ensembl
Rnor_6.0 Ensembl201,956,577 - 1,980,101 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085050   ⟹   ENSRNOP00000075181
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,534 - 1,493,439 (-)Ensembl
Rnor_6.0 Ensembl201,956,379 - 1,980,150 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000087524   ⟹   ENSRNOP00000070386
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,956,622 - 1,984,720 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000088396   ⟹   ENSRNOP00000072226
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,549 - 1,489,444 (-)Ensembl
Rnor_6.0 Ensembl201,955,359 - 1,980,253 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089485
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,959,633 - 1,960,651 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090936   ⟹   ENSRNOP00000071413
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl201,464,534 - 1,493,439 (-)Ensembl
Rnor_6.0 Ensembl201,956,622 - 1,984,720 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090937   ⟹   ENSRNOP00000069181
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,956,555 - 1,984,863 (-)Ensembl
RefSeq Acc Id: NM_031028   ⟹   NP_112290
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2201,464,534 - 1,493,994 (-)NCBI
Rnor_6.0201,955,344 - 1,984,802 (-)NCBI
Rnor_5.0203,996,333 - 4,025,508 (-)NCBI
RGSC_v3.4201,553,297 - 1,582,426 (-)RGD
Celera202,173,047 - 2,202,332 (-)RGD
Sequence:
RefSeq Acc Id: XM_006255879   ⟹   XP_006255941
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2201,464,534 - 1,494,112 (-)NCBI
Rnor_6.0201,955,352 - 1,984,907 (-)NCBI
Rnor_5.0203,996,333 - 4,025,508 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099118   ⟹   XP_038955046
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2201,465,110 - 1,493,923 (-)NCBI
RefSeq Acc Id: XR_005497343
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2201,469,834 - 1,494,114 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_112290   ⟸   NM_031028
- Peptide Label: precursor
- UniProtKB: Q9Z0U4 (UniProtKB/Swiss-Prot),   Q6MFX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255941   ⟸   XM_006255879
- Peptide Label: isoform X1
- UniProtKB: Q9Z0U4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074507   ⟸   ENSRNOT00000079445
RefSeq Acc Id: ENSRNOP00000075610   ⟸   ENSRNOT00000084582
RefSeq Acc Id: ENSRNOP00000075630   ⟸   ENSRNOT00000082545
RefSeq Acc Id: ENSRNOP00000070386   ⟸   ENSRNOT00000087524
RefSeq Acc Id: ENSRNOP00000075181   ⟸   ENSRNOT00000085050
RefSeq Acc Id: ENSRNOP00000047498   ⟸   ENSRNOT00000051634
RefSeq Acc Id: ENSRNOP00000071413   ⟸   ENSRNOT00000090936
RefSeq Acc Id: ENSRNOP00000069181   ⟸   ENSRNOT00000090937
RefSeq Acc Id: ENSRNOP00000047788   ⟸   ENSRNOT00000040232
RefSeq Acc Id: ENSRNOP00000072226   ⟸   ENSRNOT00000088396
RefSeq Acc Id: XP_038955046   ⟸   XM_039099118
- Peptide Label: isoform X2
Protein Domains
G_PROTEIN_RECEP_F3_4   Sushi

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701271
Promoter ID:EPDNEW_R11791
Type:single initiation site
Name:Gabbr1_2
Description:gamma-aminobutyric acid type B receptor subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11792  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0201,980,263 - 1,980,323EPDNEW
RGD ID:13701279
Promoter ID:EPDNEW_R11792
Type:initiation region
Name:Gabbr1_1
Description:gamma-aminobutyric acid type B receptor subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11791  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0201,984,830 - 1,984,890EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621537 AgrOrtholog
Ensembl Genes ENSRNOG00000000774 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000047498 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000047788 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000069181 UniProtKB/TrEMBL
  ENSRNOP00000070386 UniProtKB/TrEMBL
  ENSRNOP00000071413 UniProtKB/TrEMBL
  ENSRNOP00000072226 UniProtKB/Swiss-Prot
  ENSRNOP00000074507 UniProtKB/TrEMBL
  ENSRNOP00000075181 UniProtKB/Swiss-Prot
  ENSRNOP00000075610 UniProtKB/Swiss-Prot
  ENSRNOP00000075630 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000040232 UniProtKB/TrEMBL
  ENSRNOT00000051634 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000079445 UniProtKB/TrEMBL
  ENSRNOT00000082545 UniProtKB/Swiss-Prot
  ENSRNOT00000084582 UniProtKB/Swiss-Prot
  ENSRNOT00000085050 UniProtKB/Swiss-Prot
  ENSRNOT00000087524 UniProtKB/TrEMBL
  ENSRNOT00000088396 UniProtKB/Swiss-Prot
  ENSRNOT00000090936 UniProtKB/TrEMBL
  ENSRNOT00000090937 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR3_GABA-B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_3_GABA_rcpt_B1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 81657 ENTREZGENE
PANTHER PTHR10519 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANF_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gabbr1 PhenoGen
PROSITE G_PROTEIN_RECEP_F3_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUSHI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CCP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57535 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUQ1_RAT UniProtKB/TrEMBL
  B5D5S8_RAT UniProtKB/TrEMBL
  GABR1_RAT UniProtKB/Swiss-Prot
  Q5CC43_RAT UniProtKB/TrEMBL
  Q5CC44_RAT UniProtKB/TrEMBL
  Q6MFX8 ENTREZGENE, UniProtKB/TrEMBL
  Q719L2_RAT UniProtKB/TrEMBL
  Q924M0_RAT UniProtKB/TrEMBL
  Q9Z0U4 ENTREZGENE
UniProt Secondary A0A0A0MY30 UniProtKB/TrEMBL
  F7FE05 UniProtKB/TrEMBL
  O08620 UniProtKB/Swiss-Prot
  O08621 UniProtKB/Swiss-Prot
  Q9Z0F9 UniProtKB/Swiss-Prot
  Q9Z308 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Gabbr1  gamma-aminobutyric acid type B receptor subunit 1  Gabbr1  gamma-aminobutyric acid (GABA) B receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-11 Gabbr1  gamma-aminobutyric acid type B receptor subunit 1  Gabbr1  gamma-aminobutyric acid type B receptor subunit 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Gabbr1  gamma-aminobutyric acid (GABA) B receptor 1    gamma-aminobutyric acid (GABA) B receptor, 1  Name updated 1299863 APPROVED
2002-08-07 Gabbr1  gamma-aminobutyric acid (GABA) B receptor, 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression in cerebellar Purkinje cells, cerebral cortex, thalamus and hippocampal CA1 and CA3 regions of the brain 632816
gene_expression expressed in calvarial osteoblasts 625463
gene_mapping found within the rat major histocompatibility RT1 complex 1300431
gene_product member of the metabotropic G-protein-coupled receptor for gamma-aminobutyric acid (GABA) family 632816