Dhx36 (DEAH-box helicase 36) - Rat Genome Database

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Gene: Dhx36 (DEAH-box helicase 36) Rattus norvegicus
Analyze
Symbol: Dhx36
Name: DEAH-box helicase 36
RGD ID: 1308767
Description: Enables pre-miRNA binding activity. Involved in positive regulation of dendritic spine morphogenesis; positive regulation of gene expression; and positive regulation of intracellular mRNA localization. Located in axon; dendrite; and perikaryon. Orthologous to human DHX36 (DEAH-box helicase 36); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-dependent DNA/RNA helicase DHX36; ATP-dependent RNA helicase DHX36; DEAD/H box polypeptide 36; DEAH (Asp-Glu-Ala-His) box polypeptide 36; DEAH-box protein 36; G4-resolvase-1; G4R1; LOC310461; MLE-like protein 1; probable ATP-dependent RNA helicase DHX36
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82149,006,089 - 149,044,192 (-)NCBIGRCr8
mRatBN7.22146,856,469 - 146,894,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2146,856,469 - 146,894,572 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2153,533,266 - 153,574,345 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02151,638,135 - 151,676,173 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02146,270,518 - 146,308,556 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02152,785,844 - 152,824,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2152,785,844 - 152,824,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02172,178,850 - 172,217,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42152,122,767 - 152,161,219 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12152,075,160 - 152,111,181 (-)NCBI
Celera2141,195,467 - 141,233,553 (-)NCBICelera
Cytogenetic Map2q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 84 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Dhx36Rat(1->4)-beta-D-glucan multiple interactionsISORGD:13187336480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of DHX36 mRNACTDPMID:36331819
Dhx36Rat(S)-nicotine increases expressionISORGD:13187336480464Nicotine results in increased expression of DHX36 mRNACTDPMID:17997037
Dhx36Rat1,2-dimethylhydrazine decreases expressionISORGD:131873364804641,2-Dimethylhydrazine results in decreased expression of DHX36 mRNACTDPMID:22206623
Dhx36Rat1-chloro-2,4-dinitrobenzene affects bindingISORGD:13187326480464Dinitrochlorobenzene binds to DHX36 proteinCTDPMID:32991956
Dhx36Rat17beta-estradiol increases expressionISORGD:13187336480464Estradiol results in increased expression of DHX36 mRNACTDPMID:39298647
Dhx36Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISORGD:131873264804642,2',4,4'-tetrabromodiphenyl ether results in decreased expression of DHX36 proteinCTDPMID:31675489
Dhx36Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:13187336480464Tetrachlorodibenzodioxin results in increased expression of DHX36 mRNACTDPMID:19465110
Dhx36Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of DHX36 mRNACTDPMID:34747641
Dhx36Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:13187336480464Tetrachlorodibenzodioxin affects the expression of DHX36 mRNACTDPMID:21570461
Dhx36Rat2,4,6-tribromophenol decreases expressionISORGD:131873264804642,4,6-tribromophenol results in decreased expression of DHX36 mRNACTDPMID:31675489
Dhx36Rat2,6-dinitrotoluene affects expressionEXP 64804642,6-dinitrotoluene affects the expression of DHX36 mRNACTDPMID:21346803
Dhx36Rat2-methylcholine affects expressionISORGD:13187326480464beta-methylcholine affects the expression of DHX36 mRNACTDPMID:21179406
Dhx36Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISORGD:13187326480464tetrabromobisphenol A results in decreased expression of DHX36 proteinCTDPMID:31675489
Dhx36Rat4,4'-diaminodiphenylmethane decreases expressionISORGD:131873364804644,4'-diaminodiphenylmethane results in decreased expression of DHX36 mRNACTDPMID:18648102
Dhx36Rat4,4'-sulfonyldiphenol increases expressionISORGD:13187336480464bisphenol S results in increased expression of DHX36 mRNACTDPMID:39298647
Dhx36Rat4-amino-2,6-dinitrotoluene affects expressionEXP 64804644-amino-2,6-dinitrotoluene affects the expression of DHX36 mRNACTDPMID:21346803
Dhx36Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of DHX36 mRNACTDPMID:38685447
Dhx36Rataristolochic acid A decreases expressionISORGD:13187326480464aristolochic acid I results in decreased expression of DHX36 mRNACTDPMID:33212167
Dhx36Ratarsane multiple interactionsISORGD:13187326480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...CTDPMID:39836092
Dhx36Ratarsenic atom multiple interactionsISORGD:13187326480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...CTDPMID:39836092

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Biological Process
1 to 20 of 72 rows

  
Object Symbol
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Original Reference(s)
Dhx36Rat3'-UTR-mediated mRNA destabilization involved_inISSUniProtKB:Q9H2U11600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36Rat3'-UTR-mediated mRNA destabilization involved_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Rat3'-UTR-mediated mRNA destabilization involved_inISORGD:13187321624291 PMID:26489465RGDPMID:26489465
Dhx36Ratcell differentiation involved_inIEAUniProtKB-KW:KW-02211600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36Ratcellular response to arsenite ion involved_inISORGD:13187321624291 PMID:18854321RGDPMID:18854321
Dhx36Ratcellular response to arsenite ion involved_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratcellular response to heat involved_inISORGD:13187321624291 PMID:18854321RGDPMID:18854321
Dhx36Ratcellular response to heat involved_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratcellular response to UV involved_inISSUniProtKB:Q9H2U11600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36Ratcellular response to UV involved_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratcellular response to UV involved_inISORGD:13187321624291 PMID:27940037RGDPMID:27940037
Dhx36Ratdefense response to virus involved_inIEAUniProtKB-KW:KW-00511600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36Ratimmune system process involved_inIEAUniProtKB-KW:KW-03911600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36Ratinnate immune response involved_inIEAUniProtKB-KW:KW-03991600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36Ratnegative regulation of translation involved_inISSUniProtKB:Q9H2U11600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36Ratnegative regulation of translation involved_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratnegative regulation of translation involved_inISORGD:13187321624291 PMID:24369427RGDPMID:24369427
Dhx36Ratossification involved_inISORGD:13187331624291 PMID:21590736RGDPMID:21590736
Dhx36Ratossification involved_inIEAUniProtKB:Q8VHK9|ensembl:ENSMUSP000000293361600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratpositive regulation of canonical NF-kappaB signal transduction involved_inISORGD:13187331624291 PMID:21703541RGDPMID:21703541
1 to 20 of 72 rows

Cellular Component
1 to 20 of 42 rows

  
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Original Reference(s)
Dhx36Rataxon located_inIDA 13792545PMID:23651854UniProt 
Dhx36Rataxon located_inIEAUniProtKB-SubCell:SL-02791600115GO_REF:0000044UniProtGO_REF:0000044
Dhx36Ratcell projection located_inIEAUniProtKB-KW:KW-09661600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36Ratchromosome located_inIEAUniProtKB-KW:KW-01581600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36Ratchromosome, telomeric region located_inISORGD:13187321624291 PMID:20472641, PMID:21846770RGDPMID:20472641|PMID:21846770
Dhx36Ratchromosome, telomeric region located_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratchromosome, telomeric region located_inIEAUniProtKB-SubCell:SL-02761600115GO_REF:0000044UniProtGO_REF:0000044
Dhx36Ratchromosome, telomeric region located_inIEAUniProtKB-KW:KW-07791600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36Ratchromosome, telomeric region located_inISSUniProtKB:Q9H2U11600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36Ratcytoplasm located_inISORGD:13187321624291 PMID:14731398, PMID:18279852, PMID:18854321, PMID:20696886RGDPMID:14731398|PMID:18279852|PMID:18854321|PMID:20696886
Dhx36Ratcytoplasm located_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Dhx36Ratcytoplasm is_active_inIBAMGI:1919412|MGI:1920081|PANTHER:PTN002707150|UniProtKB:Q7L2E3|UniProtKB:Q9H2U11600115GO_REF:0000033GO_CentralGO_REF:0000033
Dhx36Ratcytoplasm located_inISSUniProtKB:Q9H2U11600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36Ratcytoplasmic stress granule located_inISORGD:13187321624291 PMID:18854321RGDPMID:18854321
Dhx36Ratcytoplasmic stress granule located_inIEAUniProtKB-SubCell:SL-04961600115GO_REF:0000044UniProtGO_REF:0000044
Dhx36Ratcytoplasmic stress granule located_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratcytosol located_inISORGD:1318732|UniProtKB:Q9H2U1-1|UniProtKB:Q9H2U1-2|UniProtKB:Q9H2U1-31624291 RGDGO_REF:0000052
Dhx36Ratcytosol located_inIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
1 to 20 of 81 rows

  
Object Symbol
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Evidence
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Reference
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Original Reference(s)
Dhx36RatATP binding enablesISSUniProtKB:Q05B791600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36RatATP binding enablesIEAInterPro:IPR0115451600115GO_REF:0000002InterProGO_REF:0000002
Dhx36RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36RatATP hydrolysis activity enablesIEARHEA:130651600115GO_REF:0000116RHEAGO_REF:0000116
Dhx36RatATP-dependent activity, acting on DNA enablesISORGD:13187321624291 PMID:21586581RGDPMID:21586581
Dhx36RatATP-dependent activity, acting on DNA enablesIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratcatalytic activity, acting on a nucleic acid enablesIEAUniProtKB:Q8VHK9|ensembl:ENSMUSP000000293361600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratcatalytic activity, acting on a nucleic acid enablesIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36Ratcatalytic activity, acting on a nucleic acid enablesISSUniProtKB:Q05B791600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36Ratcatalytic activity, acting on a nucleic acid enablesISORGD:13187321624291 PMID:16150737, PMID:18842585RGDPMID:16150737|PMID:18842585
Dhx36Ratcatalytic activity, acting on a nucleic acid enablesISSUniProtKB:Q8VHK91600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36Ratcatalytic activity, acting on a nucleic acid enablesISORGD:13187331624291 PMID:25611385RGDPMID:25611385
Dhx36RatDNA binding enablesIEAUniProtKB-KW:KW-02381600115GO_REF:0000043UniProtGO_REF:0000043
Dhx36RatDNA helicase activity enablesISSUniProtKB:Q8VHK91600115GO_REF:0000024UniProtGO_REF:0000024
Dhx36RatDNA helicase activity enablesISORGD:13187331624291 PMID:25611385RGDPMID:25611385
Dhx36RatDNA helicase activity enablesIBAFB:FBgn0032883|MGI:1919412|PANTHER:PTN001053965|UniProtKB:Q9H2U11600115GO_REF:0000033GO_CentralGO_REF:0000033
Dhx36RatDNA helicase activity enablesIEAUniProtKB:Q8VHK9|ensembl:ENSMUSP000000293361600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36RatDNA helicase activity enablesIEAUniProtKB:Q9H2U1|ensembl:ENSP000004170781600115GO_REF:0000107EnsemblGO_REF:0000107
Dhx36RatDNA helicase activity enablesISORGD:13187321624291 PMID:16150737, PMID:18842585, PMID:25579584RGDPMID:16150737|PMID:18842585|PMID:25579584
Dhx36Ratdouble-stranded RNA binding enablesISORGD:13187321624291 PMID:21266579RGDPMID:21266579
1 to 20 of 81 rows

Imported Annotations - KEGG (archival)

Object Symbol
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Evidence
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Reference
Notes
Source
Original Reference(s)
Dhx36RatRNA degradation pathway  IEA 6907045 KEGGrno:03018

#
Reference Title
Reference Citation
1. The DEAH-box helicase DHX36 mediates dendritic localization of the neuronal precursor-microRNA-134. Bicker S, etal., Genes Dev. 2013 May 1;27(9):991-6. doi: 10.1101/gad.211243.112.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:14731398   PMID:16150737   PMID:18279852   PMID:18570454   PMID:18842585   PMID:18854321   PMID:20472641   PMID:20696886   PMID:21149580   PMID:21266579   PMID:21586581   PMID:21590736  
PMID:21703541   PMID:21846770   PMID:21993297   PMID:22238380   PMID:22422825   PMID:22658674   PMID:22681889   PMID:24151078   PMID:24369427   PMID:25579584   PMID:25611385   PMID:26489465  
PMID:27940037  



Dhx36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82149,006,089 - 149,044,192 (-)NCBIGRCr8
mRatBN7.22146,856,469 - 146,894,577 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2146,856,469 - 146,894,572 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2153,533,266 - 153,574,345 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02151,638,135 - 151,676,173 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02146,270,518 - 146,308,556 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02152,785,844 - 152,824,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2152,785,844 - 152,824,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02172,178,850 - 172,217,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42152,122,767 - 152,161,219 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12152,075,160 - 152,111,181 (-)NCBI
Celera2141,195,467 - 141,233,553 (-)NCBICelera
Cytogenetic Map2q31NCBI
DHX36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383154,272,546 - 154,324,487 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3154,272,546 - 154,324,487 (-)EnsemblGRCh38hg38GRCh38
GRCh373153,990,335 - 154,042,276 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363155,476,152 - 155,524,971 (-)NCBINCBI36Build 36hg18NCBI36
Build 343155,476,159 - 155,524,973NCBI
Celera3152,414,134 - 152,462,946 (-)NCBICelera
Cytogenetic Map3q25.2NCBI
HuRef3151,388,213 - 151,437,233 (-)NCBIHuRef
CHM1_13153,956,666 - 154,005,426 (-)NCBICHM1_1
T2T-CHM13v2.03157,046,825 - 157,098,745 (-)NCBIT2T-CHM13v2.0
Dhx36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39362,375,436 - 62,414,464 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl362,375,434 - 62,414,425 (-)EnsemblGRCm39 Ensembl
GRCm38362,468,015 - 62,507,034 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl362,468,013 - 62,507,004 (-)EnsemblGRCm38mm10GRCm38
MGSCv37362,272,564 - 62,310,910 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36362,558,012 - 62,594,917 (-)NCBIMGSCv36mm8
Celera362,146,120 - 62,183,742 (-)NCBICelera
Cytogenetic Map3E1NCBI
cM Map329.97NCBI
Dhx36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554485,634,072 - 5,676,319 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554485,634,072 - 5,676,272 (-)NCBIChiLan1.0ChiLan1.0
DHX36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22152,190,111 - 152,241,082 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13152,194,843 - 152,245,768 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03151,331,468 - 151,382,406 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13158,885,041 - 158,935,952 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3158,885,541 - 158,935,871 (-)Ensemblpanpan1.1panPan2
DHX36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12348,404,351 - 48,456,360 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2348,407,316 - 48,456,654 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2348,271,774 - 48,335,495 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02349,034,891 - 49,086,747 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2349,036,423 - 49,086,673 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12348,615,676 - 48,679,491 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02348,671,780 - 48,735,432 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02348,954,309 - 49,018,059 (-)NCBIUU_Cfam_GSD_1.0
Dhx36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560287,746,909 - 87,787,083 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365191,946,652 - 1,987,070 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365191,946,684 - 1,987,036 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1394,298,794 - 94,350,308 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11394,298,790 - 94,350,333 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213102,367,281 - 102,396,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DHX36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11536,387,242 - 36,438,133 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1536,387,228 - 36,437,606 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660419,049,856 - 9,103,295 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dhx36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473031,855,992 - 31,914,253 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473031,857,157 - 31,913,985 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Dhx36
213 total Variants

Predicted Target Of
Summary Value
Count of predictions:562
Count of miRNA genes:264
Interacting mature miRNAs:338
Transcripts:ENSRNOT00000019824
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 63 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2102803808147803808Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1358360Sradr2Stress Responsive Adrenal Weight QTL 210.24adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)2129164097152195315Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat

1 to 10 of 63 rows
RH128402  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22146,856,637 - 146,856,834 (+)MAPPERmRatBN7.2
Rnor_6.02152,786,013 - 152,786,209NCBIRnor6.0
Rnor_5.02172,179,019 - 172,179,215UniSTSRnor5.0
RGSC_v3.42152,122,936 - 152,123,132UniSTSRGSC3.4
Celera2141,195,636 - 141,195,832UniSTS
RH 3.4 Map18390.0UniSTS
RH 3.4 Map2957.4UniSTS
Cytogenetic Map2q31UniSTS
AU022184  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22146,858,763 - 146,858,872 (+)MAPPERmRatBN7.2
Rnor_6.02152,788,139 - 152,788,247NCBIRnor6.0
Rnor_5.02172,181,145 - 172,181,253UniSTSRnor5.0
RGSC_v3.42152,125,062 - 152,125,170UniSTSRGSC3.4
Celera2141,197,762 - 141,197,870UniSTS
Cytogenetic Map2q31UniSTS
BE115449  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22146,863,018 - 146,863,168 (+)MAPPERmRatBN7.2
Rnor_6.02152,792,393 - 152,792,542NCBIRnor6.0
Rnor_5.02172,185,399 - 172,185,548UniSTSRnor5.0
RGSC_v3.42152,129,316 - 152,129,465UniSTSRGSC3.4
Celera2141,202,016 - 141,202,165UniSTS
RH 3.4 Map2960.3UniSTS
Cytogenetic Map2q31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000019824   ⟹   ENSRNOP00000019824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2146,856,469 - 146,894,572 (-)Ensembl
Rnor_6.0 Ensembl2152,785,844 - 152,824,547 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118321   ⟹   ENSRNOP00000086951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2146,856,469 - 146,894,572 (-)Ensembl
RefSeq Acc Id: NM_001107678   ⟹   NP_001101148
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82149,006,089 - 149,044,191 (-)NCBI
mRatBN7.22146,856,469 - 146,894,572 (-)NCBI
Rnor_6.02152,785,844 - 152,824,547 (-)NCBI
Rnor_5.02172,178,850 - 172,217,986 (-)NCBI
RGSC_v3.42152,122,767 - 152,161,219 (-)RGD
Celera2141,195,467 - 141,233,553 (-)RGD
Sequence:
RefSeq Acc Id: XM_008761047   ⟹   XP_008759269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82149,010,687 - 149,044,192 (-)NCBI
mRatBN7.22146,862,811 - 146,894,577 (-)NCBI
Rnor_6.02152,791,525 - 152,824,549 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005500288
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82149,006,203 - 149,044,192 (-)NCBI
mRatBN7.22146,856,583 - 146,894,576 (-)NCBI
RefSeq Acc Id: XR_351724
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82149,006,203 - 149,044,192 (-)NCBI
mRatBN7.22146,856,583 - 146,894,576 (-)NCBI
Rnor_6.02152,785,958 - 152,824,549 (-)NCBI
Rnor_5.02172,178,850 - 172,217,986 (-)NCBI
Sequence:
Protein RefSeqs NP_001101148 (Get FASTA)   NCBI Sequence Viewer  
  XP_008759269 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D4A2Z8 (Get FASTA)   NCBI Sequence Viewer  
  EDM14820 (Get FASTA)   NCBI Sequence Viewer  
  EDM14821 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019824
  ENSRNOP00000019824.5
RefSeq Acc Id: NP_001101148   ⟸   NM_001107678
- UniProtKB: D4A2Z8 (UniProtKB/TrEMBL),   A0A8I6A6W1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759269   ⟸   XM_008761047
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000019824   ⟸   ENSRNOT00000019824
Ensembl Acc Id: ENSRNOP00000086951   ⟸   ENSRNOT00000118321
Name Modeler Protein Id AA Range Protein Structure
AF-D4A2Z8-F1-model_v2 AlphaFold D4A2Z8 1-1000 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691355
Promoter ID:EPDNEW_R1879
Type:multiple initiation site
Name:Dhx36_1
Description:DEAH-box helicase 36
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02152,824,520 - 152,824,580EPDNEW


1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-52943 BioCyc
Ensembl Genes ENSRNOG00000014599 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019824 ENTREZGENE
  ENSRNOT00000019824.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.120.1080 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/Swiss-Prot
  DNA/RNA_helicase_DEAH_CS UniProtKB/Swiss-Prot
  DUF1605 UniProtKB/Swiss-Prot
  HA2_WH UniProtKB/Swiss-Prot
  Helicase-assoc_dom UniProtKB/Swiss-Prot
  Helicase_ATP-bd UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:310461 UniProtKB/Swiss-Prot
NCBI Gene 310461 ENTREZGENE
PANTHER ATP-DEPENDENT DNA/RNA HELICASE DHX36 UniProtKB/Swiss-Prot
  ATP-DEPENDENT RNA HELICASE UniProtKB/Swiss-Prot
Pfam DEAD UniProtKB/Swiss-Prot
  HA2 UniProtKB/Swiss-Prot
  HA2_C UniProtKB/Swiss-Prot
  Helicase_C UniProtKB/Swiss-Prot
  OB_NTP_bind UniProtKB/Swiss-Prot
PhenoGen Dhx36 PhenoGen
PROSITE DEAH_ATP_HELICASE UniProtKB/Swiss-Prot
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot
  HELICASE_CTER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014599 RatGTEx
SMART DEXDc UniProtKB/Swiss-Prot
  HA2 UniProtKB/Swiss-Prot
  HELICc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I6A6W1 ENTREZGENE, UniProtKB/TrEMBL
  D4A2Z8 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-13 Dhx36  DEAH-box helicase 36  Dhx36  DEAH (Asp-Glu-Ala-His) box polypeptide 36  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dhx36  DEAH (Asp-Glu-Ala-His) box polypeptide 36   Dhx36_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 36 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dhx36_predicted  DEAH (Asp-Glu-Ala-His) box polypeptide 36 (predicted)      Symbol and Name status set to approved 70820 APPROVED