DHX36 (DEAH-box helicase 36) - Rat Genome Database

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Gene: DHX36 (DEAH-box helicase 36) Sus scrofa
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Symbol: DHX36
Name: DEAH-box helicase 36
RGD ID: 14228039
Description: ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); mRNA 3'-UTR binding (ortholog); pre-miRNA binding (ortholog); INVOLVED IN negative regulation of translation (ortholog); positive regulation of dendritic spine morphogenesis (ortholog); positive regulation of gene expression (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ATP-dependent RNA helicase DHX36; DEAH (Asp-Glu-Ala-His) box polypeptide 36 tv1; DEAH (Asp-Glu-Ala-His) box polypeptide 36 tv2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1394,298,790 - 94,350,312 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11394,298,790 - 94,350,333 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213102,367,281 - 102,396,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
3'-UTR-mediated mRNA destabilization  (IEA)
cellular response to arsenite ion  (IEA)
cellular response to heat  (IEA)
cellular response to UV  (IEA)
DNA duplex unwinding  (IEA)
G-quadruplex DNA unwinding  (IEA)
negative regulation of translation  (ISO)
ossification  (IEA)
positive regulation of cardioblast differentiation  (IEA)
positive regulation of cytoplasmic translation  (IEA)
positive regulation of dendritic spine morphogenesis  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of hematopoietic progenitor cell differentiation  (IEA)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (IEA)
positive regulation of interferon-alpha production  (IEA)
positive regulation of intracellular mRNA localization  (ISO)
positive regulation of mRNA 3'-end processing  (IEA)
positive regulation of myeloid dendritic cell cytokine production  (IEA)
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  (IEA)
positive regulation of telomere maintenance  (ISO)
positive regulation of telomere maintenance via telomere lengthening  (IEA)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription initiation from RNA polymerase II promoter  (IEA)
regulation of embryonic development  (IEA)
regulation of mRNA stability  (ISO)
regulation of transcription by RNA polymerase III  (IEA)
regulation of transcription from RNA polymerase II promoter involved in spermatogenesis  (IEA)
response to exogenous dsRNA  (IEA,ISO)
response to virus  (IEA,ISO)
RNA secondary structure unwinding  (IEA)
spermatogenesis  (ISO)
telomerase RNA stabilization  (IEA)

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
DHX36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1394,298,790 - 94,350,312 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11394,298,790 - 94,350,333 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213102,367,281 - 102,396,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DHX36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3154,272,546 - 154,324,487 (-)EnsemblGRCh38hg38GRCh38
GRCh383154,272,546 - 154,324,487 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373153,990,335 - 154,042,276 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363155,476,152 - 155,524,971 (-)NCBINCBI36hg18NCBI36
Build 343155,476,159 - 155,524,973NCBI
Celera3152,414,134 - 152,462,946 (-)NCBI
Cytogenetic Map3q25.2NCBI
HuRef3151,388,213 - 151,437,233 (-)NCBIHuRef
CHM1_13153,956,666 - 154,005,426 (-)NCBICHM1_1
Dhx36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39362,375,436 - 62,414,464 (-)NCBIGRCm39mm39
GRCm39 Ensembl362,375,434 - 62,414,425 (-)Ensembl
GRCm38362,468,015 - 62,507,034 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl362,468,013 - 62,507,004 (-)EnsemblGRCm38mm10GRCm38
MGSCv37362,272,564 - 62,310,910 (-)NCBIGRCm37mm9NCBIm37
MGSCv36362,558,012 - 62,594,917 (-)NCBImm8
Celera362,146,120 - 62,183,742 (-)NCBICelera
Cytogenetic Map3E1NCBI
Dhx36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22146,856,469 - 146,894,577 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2146,856,469 - 146,894,572 (-)Ensembl
Rnor_6.02152,785,844 - 152,824,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2152,785,844 - 152,824,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02172,178,850 - 172,217,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42152,122,767 - 152,161,219 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12152,075,160 - 152,111,181 (-)NCBI
Celera2141,195,467 - 141,233,553 (-)NCBICelera
Cytogenetic Map2q31NCBI
Dhx36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554485,634,072 - 5,676,319 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554485,634,072 - 5,676,272 (-)NCBIChiLan1.0ChiLan1.0
DHX36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13158,885,041 - 158,935,952 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3158,885,541 - 158,935,871 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03151,331,468 - 151,382,406 (-)NCBIMhudiblu_PPA_v0panPan3
DHX36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12348,404,351 - 48,456,360 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2348,407,316 - 48,456,654 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2348,271,774 - 48,335,495 (-)NCBI
ROS_Cfam_1.02349,034,891 - 49,086,747 (-)NCBI
UMICH_Zoey_3.12348,615,676 - 48,679,491 (-)NCBI
UNSW_CanFamBas_1.02348,671,780 - 48,735,432 (-)NCBI
UU_Cfam_GSD_1.02348,954,309 - 49,018,059 (-)NCBI
Dhx36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560287,746,909 - 87,787,083 (+)NCBI
SpeTri2.0NW_0049365191,946,684 - 1,987,036 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11536,387,242 - 36,438,133 (+)NCBI
ChlSab1.1 Ensembl1536,387,228 - 36,437,606 (+)Ensembl
Vero_WHO_p1.0NW_0236660419,049,856 - 9,103,295 (+)NCBI
Dhx36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473031,857,157 - 31,913,985 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 9 2 3 5 2 23 2 3 3
Low 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000027576   ⟹   ENSSSCP00000026838
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1394,298,790 - 94,350,312 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000071705   ⟹   ENSSSCP00000071978
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1394,301,461 - 94,350,010 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000087582   ⟹   ENSSSCP00000073116
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1394,301,455 - 94,350,106 (-)Ensembl
RefSeq Acc Id: XM_021069687   ⟹   XP_020925346
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11394,298,790 - 94,350,333 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021069688   ⟹   XP_020925347
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11394,299,496 - 94,349,063 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020925346 (Get FASTA)   NCBI Sequence Viewer  
  XP_020925347 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein JAA74079 (Get FASTA)   NCBI Sequence Viewer  
  JAA74136 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020925346   ⟸   XM_021069687
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020925347   ⟸   XM_021069688
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSSCP00000026838   ⟸   ENSSSCT00000027576
RefSeq Acc Id: ENSSSCP00000071978   ⟸   ENSSSCT00000071705
RefSeq Acc Id: ENSSSCP00000073116   ⟸   ENSSSCT00000087582

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024916 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070003350 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000026838 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000071978 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000073116 UniProtKB/TrEMBL
  ENSSSCP00070005310 UniProtKB/TrEMBL
  ENSSSCP00070005328 UniProtKB/TrEMBL
  ENSSSCP00070005349 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000027576 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000071705 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000087582 UniProtKB/TrEMBL
  ENSSSCT00070006521 UniProtKB/TrEMBL
  ENSSSCT00070006541 UniProtKB/TrEMBL
  ENSSSCT00070006562 UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAH_CS UniProtKB/TrEMBL
  DUF1605 UniProtKB/TrEMBL
  Helicase-assoc_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene DHX36 ENTREZGENE
Pfam DEAD UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  OB_NTP_bind UniProtKB/TrEMBL
PROSITE DEAH_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A4X1SRG6_PIG UniProtKB/TrEMBL
  A0A4X1SRK3_PIG UniProtKB/TrEMBL
  A0A4X1SSZ9_PIG UniProtKB/TrEMBL
  A0A5G2R440_PIG UniProtKB/TrEMBL
  A0A5G2REN6_PIG UniProtKB/TrEMBL
  M3TYK8_PIG UniProtKB/TrEMBL
  M3VK01_PIG UniProtKB/TrEMBL
UniProt Secondary I3LRU8 UniProtKB/TrEMBL
VGNC ID VGNC:87292 ENTREZGENE