DHX36 (DEAH-box helicase 36) - Rat Genome Database

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Gene: DHX36 (DEAH-box helicase 36) Canis lupus familiaris
Analyze
Symbol: DHX36
Name: DEAH-box helicase 36
RGD ID: 12222778
Description: ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); DNA helicase activity (ortholog); double-stranded RNA binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); cellular response to arsenite ion (ortholog); cellular response to heat (ortholog); FOUND IN axon (ortholog); chromosome, telomeric region (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ATP-dependent DNA/RNA helicase DHX36; ATP-dependent RNA helicase DHX36; LOC111092001; LOW QUALITY PROTEIN: ATP-dependent DNA/RNA helicase DHX36; uncharacterized LOC111092001
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12348,404,351 - 48,456,360 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2348,407,316 - 48,456,654 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2348,271,774 - 48,335,495 (-)NCBI
ROS_Cfam_1.02349,034,891 - 49,086,747 (-)NCBI
UMICH_Zoey_3.12348,615,676 - 48,679,491 (-)NCBI
UNSW_CanFamBas_1.02348,671,780 - 48,735,432 (-)NCBI
UU_Cfam_GSD_1.02348,954,309 - 49,018,059 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
3'-UTR-mediated mRNA destabilization  (ISO)
cellular response to arsenite ion  (ISO)
cellular response to heat  (ISO)
cellular response to UV  (ISO)
G-quadruplex DNA unwinding  (ISO)
negative regulation of translation  (ISO)
ossification  (ISO)
positive regulation of cardioblast differentiation  (ISO)
positive regulation of cytoplasmic translation  (ISO)
positive regulation of dendritic spine morphogenesis  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of hematopoietic progenitor cell differentiation  (ISO)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
positive regulation of interferon-alpha production  (ISO)
positive regulation of intracellular mRNA localization  (ISO)
positive regulation of mRNA 3'-end processing  (ISO)
positive regulation of myeloid dendritic cell cytokine production  (ISO)
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  (ISO)
positive regulation of telomere maintenance  (ISO)
positive regulation of telomere maintenance via telomere lengthening  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription initiation from RNA polymerase II promoter  (ISO)
regulation of embryonic development  (ISO)
regulation of mRNA stability  (ISO)
regulation of transcription by RNA polymerase III  (ISO)
regulation of transcription from RNA polymerase II promoter involved in spermatogenesis  (ISO)
response to exogenous dsRNA  (ISO)
response to virus  (ISO)
RNA secondary structure unwinding  (ISO)
spermatogenesis  (ISO)
telomerase RNA stabilization  (ISO)

Cellular Component

References

Genomics

Comparative Map Data
DHX36
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12348,404,351 - 48,456,360 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2348,407,316 - 48,456,654 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2348,271,774 - 48,335,495 (-)NCBI
ROS_Cfam_1.02349,034,891 - 49,086,747 (-)NCBI
UMICH_Zoey_3.12348,615,676 - 48,679,491 (-)NCBI
UNSW_CanFamBas_1.02348,671,780 - 48,735,432 (-)NCBI
UU_Cfam_GSD_1.02348,954,309 - 49,018,059 (-)NCBI
DHX36
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3154,272,546 - 154,324,487 (-)EnsemblGRCh38hg38GRCh38
GRCh383154,272,546 - 154,324,487 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373153,990,335 - 154,042,276 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363155,476,152 - 155,524,971 (-)NCBINCBI36hg18NCBI36
Build 343155,476,159 - 155,524,973NCBI
Celera3152,414,134 - 152,462,946 (-)NCBI
Cytogenetic Map3q25.2NCBI
HuRef3151,388,213 - 151,437,233 (-)NCBIHuRef
CHM1_13153,956,666 - 154,005,426 (-)NCBICHM1_1
Dhx36
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39362,375,436 - 62,414,464 (-)NCBIGRCm39mm39
GRCm39 Ensembl362,375,434 - 62,414,425 (-)Ensembl
GRCm38362,468,015 - 62,507,034 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl362,468,013 - 62,507,004 (-)EnsemblGRCm38mm10GRCm38
MGSCv37362,272,564 - 62,310,910 (-)NCBIGRCm37mm9NCBIm37
MGSCv36362,558,012 - 62,594,917 (-)NCBImm8
Celera362,146,120 - 62,183,742 (-)NCBICelera
Cytogenetic Map3E1NCBI
Dhx36
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22146,856,469 - 146,894,577 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2146,856,469 - 146,894,572 (-)Ensembl
Rnor_6.02152,785,844 - 152,824,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2152,785,844 - 152,824,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02172,178,850 - 172,217,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42152,122,767 - 152,161,219 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12152,075,160 - 152,111,181 (-)NCBI
Celera2141,195,467 - 141,233,553 (-)NCBICelera
Cytogenetic Map2q31NCBI
Dhx36
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554485,634,072 - 5,676,319 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554485,634,072 - 5,676,272 (-)NCBIChiLan1.0ChiLan1.0
DHX36
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13158,885,041 - 158,935,952 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3158,885,541 - 158,935,871 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03151,331,468 - 151,382,406 (-)NCBIMhudiblu_PPA_v0panPan3
Dhx36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560287,746,909 - 87,787,083 (+)NCBI
SpeTri2.0NW_0049365191,946,684 - 1,987,036 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX36
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1394,298,790 - 94,350,312 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11394,298,790 - 94,350,333 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213102,367,281 - 102,396,208 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DHX36
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11536,387,242 - 36,438,133 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1536,387,228 - 36,437,606 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660419,049,856 - 9,103,295 (+)NCBIVero_WHO_p1.0
Dhx36
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473031,857,157 - 31,913,985 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 15 5 6 12 8 10
Low 4 5 7 6 1 6 6 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022408768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022408769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038432720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038508024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038571262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038571263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038571264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038571265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038571266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038635456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038635457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038635458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038635459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038635460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000013769   ⟹   ENSCAFP00000012733
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2348,407,316 - 48,456,654 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000074972   ⟹   ENSCAFP00000047259
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2348,407,316 - 48,456,300 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000079792   ⟹   ENSCAFP00000047387
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2348,407,316 - 48,456,654 (-)Ensembl
RefSeq Acc Id: XM_022408768   ⟹   XP_022264476
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12348,404,351 - 48,456,359 (-)NCBI
Dog10K_Boxer_Tasha2348,271,774 - 48,323,542 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022408769   ⟹   XP_022264477
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12348,404,351 - 48,456,360 (-)NCBI
Dog10K_Boxer_Tasha2348,271,774 - 48,323,543 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038432720   ⟹   XP_038288648
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02349,034,891 - 49,086,747 (-)NCBI
RefSeq Acc Id: XM_038457276   ⟹   XP_038313204
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2348,271,774 - 48,335,469 (-)NCBI
RefSeq Acc Id: XM_038457277   ⟹   XP_038313205
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2348,271,774 - 48,335,495 (-)NCBI
RefSeq Acc Id: XM_038457278   ⟹   XP_038313206
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2348,271,774 - 48,335,495 (-)NCBI
RefSeq Acc Id: XM_038508019   ⟹   XP_038363947
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12348,615,676 - 48,667,445 (-)NCBI
RefSeq Acc Id: XM_038508020   ⟹   XP_038363948
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12348,615,676 - 48,667,446 (-)NCBI
RefSeq Acc Id: XM_038508022   ⟹   XP_038363950
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12348,615,676 - 48,679,465 (-)NCBI
RefSeq Acc Id: XM_038508023   ⟹   XP_038363951
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12348,615,676 - 48,679,491 (-)NCBI
RefSeq Acc Id: XM_038508024   ⟹   XP_038363952
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12348,615,676 - 48,679,491 (-)NCBI
RefSeq Acc Id: XM_038571262   ⟹   XP_038427190
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02348,954,309 - 49,006,115 (-)NCBI
RefSeq Acc Id: XM_038571263   ⟹   XP_038427191
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02348,954,309 - 49,006,116 (-)NCBI
RefSeq Acc Id: XM_038571264   ⟹   XP_038427192
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02348,954,309 - 49,018,033 (-)NCBI
RefSeq Acc Id: XM_038571265   ⟹   XP_038427193
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02348,954,309 - 49,018,059 (-)NCBI
RefSeq Acc Id: XM_038571266   ⟹   XP_038427194
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02348,954,309 - 49,018,059 (-)NCBI
RefSeq Acc Id: XM_038635456   ⟹   XP_038491384
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02348,671,780 - 48,723,057 (-)NCBI
RefSeq Acc Id: XM_038635457   ⟹   XP_038491385
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02348,671,780 - 48,723,058 (-)NCBI
RefSeq Acc Id: XM_038635458   ⟹   XP_038491386
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02348,671,780 - 48,735,406 (-)NCBI
RefSeq Acc Id: XM_038635459   ⟹   XP_038491387
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02348,671,780 - 48,735,432 (-)NCBI
RefSeq Acc Id: XM_038635460   ⟹   XP_038491388
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02348,671,780 - 48,735,432 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_022264477   ⟸   XM_022408769
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_022264476   ⟸   XM_022408768
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000047259   ⟸   ENSCAFT00000074972
RefSeq Acc Id: ENSCAFP00000012733   ⟸   ENSCAFT00000013769
RefSeq Acc Id: ENSCAFP00000047387   ⟸   ENSCAFT00000079792
RefSeq Acc Id: XP_038363951   ⟸   XM_038508023
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038363952   ⟸   XM_038508024
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038363950   ⟸   XM_038508022
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038363948   ⟸   XM_038508020
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038363947   ⟸   XM_038508019
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038491387   ⟸   XM_038635459
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038491388   ⟸   XM_038635460
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038491386   ⟸   XM_038635458
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038491385   ⟸   XM_038635457
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038491384   ⟸   XM_038635456
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038288648   ⟸   XM_038432720
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038313205   ⟸   XM_038457277
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038313206   ⟸   XM_038457278
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038313204   ⟸   XM_038457276
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038427193   ⟸   XM_038571265
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038427194   ⟸   XM_038571266
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038427192   ⟸   XM_038571264
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038427191   ⟸   XM_038571263
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038427190   ⟸   XM_038571262
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008673 Ensembl
NCBI Gene DHX36 ENTREZGENE
VGNC ID VGNC:39946 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-14 DHX36  DEAH-box helicase 36  LOC111092001  uncharacterized LOC111092001  Data Merged 737654 PROVISIONAL