trichothecene - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	trichothecene	go back to main search page
Accession:	CHEBI:55517	browse the term
Definition:	Any one of a large family of chemically related mycotoxins with a structure based on a sesquiterpene skeleton. The most important structural features causing the biological activities of trichothecenes are a 12,13-epoxy ring, the presence of hydroxy or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain.
Synonyms:	related_synonym:	Formula=C15H17O2R5; SMILES=[H][C@]12O[C@]3([H])[C@H]([])[C@@H]([])[C@@](C)(C33CO3)C1(C[])C([])C([*])C(C)=C2; trichothecenes

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Rat (1525) Mouse (1531) Human (1548) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (4283) Green Monkey (0) Naked Mole-rat (0) All
Genes (1525)

15-acetyldeoxynivalenol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adrenoceptor beta 2

increases expression

15-acetyldeoxynivalenol results in increased expression of ADRB2 mRNA

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

angiopoietin-like 4

increases expression

15-acetyldeoxynivalenol results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

androgen receptor

decreases activity
multiple interactions

15-acetyldeoxynivalenol results in decreased activity of AR protein
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

activity-regulated cytoskeleton-associated protein

increases expression

15-acetyldeoxynivalenol results in increased expression of ARC mRNA

NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378

G

amphiregulin

increases expression

15-acetyldeoxynivalenol results in increased expression of AREG mRNA

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

AT-rich interaction domain 5A

increases expression

15-acetyldeoxynivalenol results in increased expression of ARID5A mRNA

NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597

G

ADP-ribosylation factor like GTPase 5B

increases expression

15-acetyldeoxynivalenol results in increased expression of ARL5B mRNA

NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854

G

arrestin domain containing 4

increases expression

15-acetyldeoxynivalenol results in increased expression of ARRDC4 mRNA

NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290

G

activating transcription factor 3

increases expression
multiple interactions

15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA
[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA]

PMID:19101521 PMID:22003189 PMID:23792671

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 6

increases expression

15-acetyldeoxynivalenol results in increased expression of ATF6 mRNA

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

atos homolog B

increases expression

15-acetyldeoxynivalenol results in increased expression of ATOSB mRNA

NCBI chr 5:57,260,839...57,274,524
Ensembl chr 5:57,260,841...57,268,892

G

bradykinin receptor B1

increases expression

15-acetyldeoxynivalenol results in increased expression of BDKRB1 mRNA

NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747

G

bradykinin receptor B2

increases expression

15-acetyldeoxynivalenol results in increased expression of BDKRB2 mRNA

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

G

basic helix-loop-helix family, member e40

increases expression

15-acetyldeoxynivalenol results in increased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

BTG anti-proliferation factor 2

increases expression

15-acetyldeoxynivalenol results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

similar to human chromosome 11 open reading frame 96

increases expression

15-acetyldeoxynivalenol results in increased expression of C11ORF96 mRNA

NCBI chr 3:79,920,125...79,921,368
Ensembl chr 3:79,920,129...79,921,523

G

coiled-coil domain containing 116

increases expression

15-acetyldeoxynivalenol results in increased expression of CCDC116 mRNA

NCBI chr11:83,842,707...83,850,607
Ensembl chr11:83,845,557...83,850,607

G

cholecystokinin

increases expression

15-acetyldeoxynivalenol results in increased expression of CCK protein

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

C-C motif chemokine ligand 2

increases expression

15-acetyldeoxynivalenol results in increased expression of CCL2 mRNA

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 3

increases expression

15-acetyldeoxynivalenol results in increased expression of CCL3 mRNA

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 4

increases expression

15-acetyldeoxynivalenol results in increased expression of CCL4 mRNA

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

C-C motif chemokine ligand 7

increases expression

15-acetyldeoxynivalenol results in increased expression of CCL7 mRNA

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

C-C motif chemokine receptor 7

increases expression

15-acetyldeoxynivalenol results in increased expression of CCR7 mRNA

NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309

G

cAMP responsive element modulator

increases expression

15-acetyldeoxynivalenol results in increased expression of CREM mRNA

NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989

G

C-X-C motif chemokine ligand 2

increases expression

15-acetyldeoxynivalenol results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine receptor 4

increases expression

15-acetyldeoxynivalenol results in increased expression of CXCR4 mRNA

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

G

DNA-damage inducible transcript 3

increases expression

15-acetyldeoxynivalenol results in increased expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DIX domain containing 1

increases expression

15-acetyldeoxynivalenol results in increased expression of DIXDC1 mRNA

NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090

G

distal-less homeobox 1

increases expression

15-acetyldeoxynivalenol results in increased expression of DLX1 mRNA

NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780

G

distal-less homeobox 2

increases expression

15-acetyldeoxynivalenol results in increased expression of DLX2 mRNA

NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597

G

doublesex and mab-3 related transcription factor 2

increases expression

15-acetyldeoxynivalenol results in increased expression of DMRT2 mRNA

NCBI chr 1:223,317,543...223,324,131
Ensembl chr 1:223,317,642...223,324,131

G

DnaJ heat shock protein family (Hsp40) member B5

increases expression

15-acetyldeoxynivalenol results in increased expression of DNAJB5 mRNA

NCBI chr 5:57,176,840...57,186,067
Ensembl chr 5:57,176,845...57,185,490

G

dual specificity phosphatase 10

increases expression

15-acetyldeoxynivalenol results in increased expression of DUSP10 mRNA

NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716

G

dual specificity phosphatase 8

increases expression

15-acetyldeoxynivalenol results in increased expression of DUSP8 mRNA

NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921

G

early growth response 3

increases expression

15-acetyldeoxynivalenol results in increased expression of EGR3 mRNA

NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627

G

eukaryotic translation initiation factor 2A

increases phosphorylation

15-acetyldeoxynivalenol results in increased phosphorylation of EIF2A protein

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

empty spiracles homeobox 2

increases expression

15-acetyldeoxynivalenol results in increased expression of EMX2 mRNA

NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594

G

Eph receptor B3

increases expression

15-acetyldeoxynivalenol results in increased expression of EPHB3 mRNA

NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370

G

epiregulin

increases expression

15-acetyldeoxynivalenol results in increased expression of EREG mRNA

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

endoplasmic reticulum to nucleus signaling 1

decreases expression

15-acetyldeoxynivalenol results in decreased expression of ERN1 mRNA

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

family with sequence similarity 43, member A

increases expression

15-acetyldeoxynivalenol results in increased expression of FAM43A mRNA

NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401

G

fructose-bisphosphatase 2

increases expression

15-acetyldeoxynivalenol results in increased expression of FBP2 mRNA

NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698

G

fibroblast growth factor 9

increases expression

15-acetyldeoxynivalenol results in increased expression of FGF9 mRNA

NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309

G

four-jointed box kinase 1

increases expression

15-acetyldeoxynivalenol results in increased expression of FJX1 mRNA

NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321

G

GTP binding protein overexpressed in skeletal muscle

increases expression

15-acetyldeoxynivalenol results in increased expression of GEM mRNA

NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222

G

Gfo/Idh/MocA-like oxidoreductase domain containing 1

increases expression

15-acetyldeoxynivalenol results in increased expression of GFOD1 mRNA

NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938

G

GTF2I repeat domain containing 2

increases expression

15-acetyldeoxynivalenol results in increased expression of GTF2IRD2 mRNA

NCBI chr12:22,497,767...22,536,455
Ensembl chr12:22,498,091...22,536,263

G

hyaluronan synthase 2

increases expression

15-acetyldeoxynivalenol results in increased expression of HAS2 mRNA

NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933

G

homeobox B2

increases expression

15-acetyldeoxynivalenol results in increased expression of HOXB2 mRNA

NCBI chr10:81,317,828...81,320,220
Ensembl chr10:81,318,026...81,320,192

G

heparanase 2 (inactive)

increases expression

15-acetyldeoxynivalenol results in increased expression of HPSE2 mRNA

NCBI chr 1:241,582,904...242,284,348
Ensembl chr 1:241,583,187...242,246,118

G

heat shock protein family A (Hsp70) member 5

decreases expression

15-acetyldeoxynivalenol results in decreased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

interleukin 10 receptor subunit alpha

increases expression

15-acetyldeoxynivalenol results in increased expression of IL10RA mRNA

NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061

G

interleukin 1 beta

increases expression

15-acetyldeoxynivalenol results in increased expression of IL1B mRNA

PMID:23792671 PMID:24793808

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

affects secretion
increases expression

15-acetyldeoxynivalenol affects the secretion of IL2 protein
15-acetyldeoxynivalenol results in increased expression of IL2 mRNA

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 4

affects secretion

15-acetyldeoxynivalenol affects the secretion of IL4 protein

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 5

affects secretion

15-acetyldeoxynivalenol affects the secretion of IL5 protein

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

increases expression

15-acetyldeoxynivalenol results in increased expression of IL6 mRNA

PMID:8560498 PMID:24793808

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

IQ motif containing N

increases expression

15-acetyldeoxynivalenol results in increased expression of IQCN mRNA

NCBI chr16:18,716,519...18,733,971
Ensembl chr16:18,716,519...18,726,261

G

immunity-related GTPase M

increases expression

15-acetyldeoxynivalenol results in increased expression of IRGM mRNA

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

G

potassium inwardly-rectifying channel, subfamily J, member 2

increases expression

15-acetyldeoxynivalenol results in increased expression of KCNJ2 mRNA

NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445

G

KLF transcription factor 10

increases expression

15-acetyldeoxynivalenol results in increased expression of KLF10 mRNA

NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994

G

mannosidase, alpha, class 1B, member 1

increases expression

15-acetyldeoxynivalenol results in increased expression of MAN1B1 mRNA

NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006

G

MFSD2 lysolipid transporter A, lysophospholipid

increases expression

15-acetyldeoxynivalenol results in increased expression of MFSD2A mRNA

NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690

G

muscle RAS oncogene homolog

increases expression

15-acetyldeoxynivalenol results in increased expression of MRAS mRNA

NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408

G

maestro heat-like repeat family member 3

increases expression

15-acetyldeoxynivalenol results in increased expression of MROH3P mRNA

NCBI chr13:47,630,004...47,665,461
Ensembl chr13:47,630,003...47,665,394

G

max dimerization protein 1

increases expression

15-acetyldeoxynivalenol results in increased expression of MXD1 mRNA

NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751

G

neuralized E3 ubiquitin protein ligase 3

increases expression

15-acetyldeoxynivalenol results in increased expression of NEURL3 mRNA

NCBI chr 9:38,494,486...38,503,352
Ensembl chr 9:38,494,489...38,502,649

G

nucleotide-binding oligomerization domain containing 2

multiple interactions

[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [15-acetyldeoxynivalenol results in increased expression of ATF3 mRNA]

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

G

nuclear receptor subfamily 4, group A, member 3

increases expression

15-acetyldeoxynivalenol results in increased expression of NR4A3 mRNA

NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733

G

NACHT and WD repeat domain containing 2

increases expression

15-acetyldeoxynivalenol results in increased expression of NWD2 mRNA

NCBI chr14:44,480,049...44,671,417
Ensembl chr14:44,482,287...44,670,299

G

protocadherin 9

increases expression

15-acetyldeoxynivalenol results in increased expression of PCDH9 mRNA

NCBI chr15:69,340,108...70,237,531
Ensembl chr15:69,340,645...70,237,538

G

period circadian regulator 1

increases expression

15-acetyldeoxynivalenol results in increased expression of PER1 mRNA

NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431

G

peroxisome proliferator-activated receptor gamma

decreases activity

15-acetyldeoxynivalenol results in decreased activity of PPARG protein

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

prostaglandin-endoperoxide synthase 2

increases expression

15-acetyldeoxynivalenol results in increased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

regulator of calcineurin 1

increases expression

15-acetyldeoxynivalenol results in increased expression of RCAN1 mRNA

NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045

G

RRAD and GEM like GTPase 2

increases expression

15-acetyldeoxynivalenol results in increased expression of REM2 mRNA

NCBI chr15:27,933,950...27,938,429
Ensembl chr15:27,933,950...27,938,429

G

regulator of G-protein signaling 16

increases expression

15-acetyldeoxynivalenol results in increased expression of RGS16 mRNA

NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857

G

ras homolog family member H

increases expression

15-acetyldeoxynivalenol results in increased expression of RHOH mRNA

NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369

G

Rho family GTPase 1

increases expression

15-acetyldeoxynivalenol results in increased expression of RND1 mRNA

NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399

G

SIX homeobox 1

increases expression

15-acetyldeoxynivalenol results in increased expression of SIX1 mRNA

NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975

G

solute carrier family 34 member 1

increases expression

15-acetyldeoxynivalenol results in increased expression of SLC34A1 mRNA

NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852

G

stathmin 4

increases expression

15-acetyldeoxynivalenol results in increased expression of STMN4 mRNA

NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253

G

storkhead box 2

increases expression

15-acetyldeoxynivalenol results in increased expression of STOX2 mRNA

NCBI chr16:44,848,179...45,087,238
Ensembl chr16:44,848,078...45,085,105

G

transcription factor AP-2 alpha

increases expression

15-acetyldeoxynivalenol results in increased expression of TFAP2A mRNA

NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507

G

thyroid hormone receptor beta

multiple interactions

[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein

NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916

G

transmembrane and coiled-coil domain family 2

increases expression

15-acetyldeoxynivalenol results in increased expression of TMCC2 mRNA

NCBI chr13:43,794,029...43,831,716
Ensembl chr13:43,794,029...43,831,716

G

transmembrane protein 88

increases expression

15-acetyldeoxynivalenol results in increased expression of TMEM88 mRNA

NCBI chr10:54,118,752...54,120,447
Ensembl chr10:54,118,752...54,120,447

G

tumor necrosis factor

increases expression

15-acetyldeoxynivalenol results in increased expression of TNF mRNA

PMID:23792671 PMID:24793808

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

uncoupling protein 1

increases expression

15-acetyldeoxynivalenol results in increased expression of UCP1 mRNA

NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852

G

zinc finger and BTB domain containing 21

increases expression

15-acetyldeoxynivalenol results in increased expression of ZBTB21 mRNA

NCBI chr11:37,312,337...37,327,040
Ensembl chr11:37,312,378...37,326,996

G

zinc finger CCCH type containing 12D

increases expression

15-acetyldeoxynivalenol results in increased expression of ZC3H12D mRNA

NCBI chr 1:2,313,110...2,348,820
Ensembl chr 1:2,314,324...2,348,819

G

zinc finger protein 2

increases expression

15-acetyldeoxynivalenol results in increased expression of ZFP2 mRNA

NCBI chr10:35,209,187...35,228,849
Ensembl chr10:35,207,260...35,228,853

G

zinc finger protein 77

increases expression

15-acetyldeoxynivalenol results in increased expression of ZNF77 mRNA

NCBI chr 7:7,269,879...7,316,286
Ensembl chr 7:7,269,927...7,286,051

3-acetyldeoxynivalenol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

decreases activity
multiple interactions

3-acetyldeoxynivalenol results in decreased activity of AR protein
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

activating transcription factor 4

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of ATF4 mRNA
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ATF4 mRNA]

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 6

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of ATF6 mRNA
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ATF6 mRNA]

PMID:20682335 PMID:35413383

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

cholecystokinin

increases expression

3-acetyldeoxynivalenol results in increased expression of CCK protein

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

C-C motif chemokine ligand 2

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of CCL2 mRNA
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CCL2 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CCL2 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CCL2 mRNA]

PMID:24793808 PMID:35413383

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 7

increases expression

3-acetyldeoxynivalenol results in increased expression of CCL7 mRNA

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

colony stimulating factor 1

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of CSF1 mRNA
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CSF1 mRNA]

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 2

multiple interactions

3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CSF2 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of CSF2 protein]

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of CSF3 mRNA]

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

C-X-C motif chemokine ligand 2

increases expression

3-acetyldeoxynivalenol results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

DNA-damage inducible transcript 3

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of DDIT3 mRNA]

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

eukaryotic translation initiation factor 2A

increases phosphorylation

3-acetyldeoxynivalenol results in increased phosphorylation of EIF2A protein

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

eukaryotic translation initiation factor 2 alpha kinase 3

increases expression

3-acetyldeoxynivalenol results in increased expression of EIF2AK3 mRNA

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2 subunit alpha

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of EIF2S1 mRNA
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of EIF2S1 mRNA]

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

endoplasmic reticulum to nucleus signaling 1

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of ERN1 mRNA]

PMID:20682335 PMID:35413383

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

heat shock protein family A (Hsp70) member 5

decreases expression
increases expression
multiple interactions

3-acetyldeoxynivalenol results in decreased expression of HSPA5 mRNA
3-acetyldeoxynivalenol results in increased expression of HSPA5 mRNA
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of HSPA5 mRNA]

PMID:20682335 PMID:35413383

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

interferon beta 1

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of IFNB1 mRNA
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IFNB1 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IFNB1 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IFNB1 mRNA]

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IFNG mRNA]

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 10

multiple interactions
increases expression

3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL10 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL10 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL10 mRNA]

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 17A

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of IL17A mRNA
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL17A protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL17A protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL17A mRNA]

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 1 alpha

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of IL1A mRNA
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1A protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1A protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL1A mRNA]

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of IL1B mRNA
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1B protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL1B protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL1B mRNA]

PMID:24793808 PMID:35413383

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

affects secretion
increases expression

3-acetyldeoxynivalenol affects the secretion of IL2 protein
3-acetyldeoxynivalenol results in increased expression of IL2 mRNA

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 4

affects secretion

3-acetyldeoxynivalenol affects the secretion of IL4 protein

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 5

affects secretion

3-acetyldeoxynivalenol affects the secretion of IL5 protein

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of IL6 mRNA
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL6 protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of IL6 protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of IL6 mRNA]

PMID:24793808 PMID:35413383

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

mitogen-activated protein kinase 8

multiple interactions
increases expression

4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of MAPK8 mRNA]

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

myeloperoxidase

multiple interactions
increases secretion

4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased secretion of MPO protein]

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

peroxisome proliferator-activated receptor gamma

decreases activity

3-acetyldeoxynivalenol results in decreased activity of PPARG protein

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

prostaglandin-endoperoxide synthase 2

increases expression

3-acetyldeoxynivalenol results in increased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

thyroid hormone receptor beta

decreases activity
multiple interactions

3-acetyldeoxynivalenol results in decreased activity of THRB protein
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein

NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916

G

tumor necrosis factor

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of TNF mRNA
3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of TNF protein; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of and results in increased secretion of TNF protein]; 4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of TNF mRNA]

PMID:24793808 PMID:35413383

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

X-box binding protein 1

increases expression
multiple interactions

3-acetyldeoxynivalenol results in increased expression of XBP1 mRNA
4-phenylbutyric acid inhibits the reaction [3-acetyldeoxynivalenol results in increased expression of XBP1 mRNA]

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

deoxynivalenol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

decreases response to substance
multiple interactions

ABCB1 protein results in decreased susceptibility to deoxynivalenol
deoxynivalenol inhibits the reaction [valspodar inhibits the reaction [ABCB1 protein results in increased export of calcein AM]]

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 3

decreases expression

deoxynivalenol results in decreased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily F member 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of ABCF1 protein

PMID:23352502 PMID:23811945

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

abl-interactor 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of ABI1 protein

NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792

G

abraxas 2, BRISC complex subunit

increases expression

deoxynivalenol results in increased expression of ABRAXAS2 mRNA

NCBI chr 1:187,647,078...187,672,660
Ensembl chr 1:187,647,067...187,672,655

G

aggrecan

decreases expression

deoxynivalenol results in decreased expression of ACAN mRNA

NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627

G

apoptotic chromatin condensation inducer 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of ACIN1 protein

NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001

G

acyl-CoA synthetase long-chain family member 4

decreases expression

deoxynivalenol results in decreased expression of ACSL4 protein

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

actin, alpha 1, skeletal muscle

affects phosphorylation

deoxynivalenol affects the phosphorylation of ACTA1 protein

NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742

G

actin, beta-like 2

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of ACTBL2 protein

NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767

G

AFG2 AAA ATPase homolog B

increases expression

deoxynivalenol results in increased expression of AFG2B mRNA

NCBI chr 3:109,694,739...109,708,356
Ensembl chr 3:109,694,757...109,707,757

G

ArfGAP with FG repeats 1

affects phosphorylation
increases expression

deoxynivalenol affects the phosphorylation of AGFG1 protein
deoxynivalenol results in increased expression of AGFG1 mRNA

PMID:23811945 PMID:31863870

NCBI chr 9:84,124,845...84,182,615
Ensembl chr 9:84,125,120...84,178,128

G

AHNAK nucleoprotein

affects phosphorylation

deoxynivalenol affects the phosphorylation of AHNAK protein

PMID:23352502 PMID:23811945

NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926

G

aryl hydrocarbon receptor

multiple interactions
increases expression

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of AHR protein]
deoxynivalenol results in increased expression of AHR mRNA; deoxynivalenol results in increased expression of AHR protein

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

ajuba LIM protein

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of AJUBA protein

NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021

G

adenylate kinase 7

decreases expression

deoxynivalenol results in decreased expression of AK7 mRNA

NCBI chr 6:124,611,789...124,679,978
Ensembl chr 6:124,611,902...124,679,961

G

A-kinase anchoring protein 8 like

increases expression

deoxynivalenol results in increased expression of AKAP8L mRNA

NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275

G

AKT serine/threonine kinase 1

multiple interactions
decreases phosphorylation
increases phosphorylation

AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; AKT1 protein affects the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of AKT1 protein; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of AKT1 protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of AKT1 protein]
[Zearalenone co-treated with deoxynivalenol] results in decreased phosphorylation of AKT1 protein

PMID:15976193 PMID:16424113 PMID:24937323 PMID:34506767 PMID:35090964

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

albumin

decreases expression
multiple interactions
increases expression

deoxynivalenol results in decreased expression of ALB protein
[deoxynivalenol co-treated with Zearalenone] affects the expression of ALB mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of ALB protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALB mRNA
deoxynivalenol results in decreased expression of ALB mRNA; deoxynivalenol results in decreased expression of ALB protein
deoxynivalenol results in increased expression of ALB mRNA

PMID:25445755 PMID:28865950 PMID:28935499

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 3 family, member B1

decreases expression

deoxynivalenol results in decreased expression of ALDH3B1 mRNA

NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921

G

aldolase, fructose-bisphosphate B

increases expression
multiple interactions

deoxynivalenol results in increased expression of ALDOB mRNA
[deoxynivalenol co-treated with Zearalenone] affects the expression of ALDOB mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of ALDOB mRNA

PMID:28865950 PMID:28935499

NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116

G

alkB homolog 1, histone H2A dioxygenase

increases expression

deoxynivalenol results in increased expression of ALKBH1 mRNA

NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759

G

alkaline phosphatase, intestinal

multiple interactions

deoxynivalenol results in decreased expression of and results in decreased activity of ALPI protein

NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877

G

alpha-kinase 2

decreases expression

deoxynivalenol results in decreased expression of ALPK2 mRNA

NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258

G

adhesion molecule with Ig like domain 2

decreases expression

deoxynivalenol results in decreased expression of AMIGO2 mRNA

NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695

G

angiopoietin like 7

decreases expression

deoxynivalenol results in decreased expression of ANGPTL7 mRNA

NCBI chr 5:158,932,096...158,937,281
Ensembl chr 5:158,932,794...158,937,324

G

ankyrin repeat domain 13C

increases expression

deoxynivalenol results in increased expression of ANKRD13C mRNA

NCBI chr 2:247,023,040...247,070,433
Ensembl chr 2:247,022,286...247,070,433

G

ankyrin repeat domain 37

decreases expression

deoxynivalenol results in decreased expression of ANKRD37 mRNA

NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963

G

anillin, actin binding protein

increases expression

deoxynivalenol results in increased expression of ANLN mRNA

NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538

G

alanyl aminopeptidase, membrane

decreases expression

deoxynivalenol results in decreased expression of ANPEP mRNA

NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789

G

amine oxidase, copper containing 1

increases activity
multiple interactions

deoxynivalenol results in increased activity of AOC1 protein
Curcumin inhibits the reaction [deoxynivalenol results in increased activity of AOC1 protein]

NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840

G

androgen receptor

decreases activity
multiple interactions

deoxynivalenol results in decreased activity of AR protein
[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of AR protein; [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol] results in decreased activity of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

arginine and glutamate rich 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of ARGLU1 protein

NCBI chr16:80,753,300...80,777,350
Ensembl chr16:80,753,315...80,777,349

G

Rho GTPase activating protein 45

affects phosphorylation

deoxynivalenol affects the phosphorylation of ARHGAP45 protein

NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268

G

arkadia (RNF111) N-terminal like PKA signaling regulator 2N

increases expression

deoxynivalenol results in increased expression of ARK2N mRNA

NCBI chr18:71,155,956...71,243,655
Ensembl chr18:71,157,700...71,243,482

G

armadillo repeat containing 10

affects phosphorylation
increases phosphorylation

deoxynivalenol affects the phosphorylation of ARMC10 protein
deoxynivalenol results in increased phosphorylation of ARMC10 protein

PMID:23352502 PMID:23811945

NCBI chr 4:13,399,004...13,414,594
Ensembl chr 4:13,395,207...13,414,548

G

activating signal cointegrator 1 complex subunit 3

increases expression

deoxynivalenol results in increased expression of ASCC3 mRNA

NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165

G

achaete-scute family bHLH transcription factor 2

increases expression

deoxynivalenol results in increased expression of ASCL2 mRNA

NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406

G

achaete-scute family bHLH transcription factor 4

increases expression

deoxynivalenol results in increased expression of ASCL4 mRNA

NCBI chr 7:17,940,972...17,943,215
Ensembl chr 7:17,941,709...17,942,146

G

asparagine synthetase (glutamine-hydrolyzing)

decreases expression

deoxynivalenol results in decreased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

activating transcription factor 1

multiple interactions
increases phosphorylation
increases expression

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF1 protein]
deoxynivalenol results in increased expression of ATF1 mRNA

PMID:16424113 PMID:22846391

NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670

G

activating transcription factor 2

increases expression
multiple interactions
increases phosphorylation
affects localization

deoxynivalenol results in increased expression of ATF2 mRNA
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of ATF2 protein]
deoxynivalenol affects the localization of ATF2 protein

PMID:12604842 PMID:15772366 PMID:22846391

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

G

activating transcription factor 3

multiple interactions
decreases expression
increases expression
increases response to substance
decreases degradation

[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of ATF3 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of ATF3 mRNA]; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; ATF3 protein affects the reaction [deoxynivalenol results in increased expression of EGR1 protein]; EP300 protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; KAT2A protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; KAT2B protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]; N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased degradation of ATF3 protein]
deoxynivalenol results in decreased expression of ATF3 mRNA
deoxynivalenol results in increased expression of ATF3 mRNA; deoxynivalenol results in increased expression of ATF3 protein; deoxynivalenol results in increased expression of ATF3 protein alternative form
ATF3 protein results in increased susceptibility to deoxynivalenol
deoxynivalenol results in decreased degradation of ATF3 mRNA; deoxynivalenol results in decreased degradation of ATF3 protein

PMID:19101521 PMID:19360757 PMID:21074547 PMID:22003189 PMID:22846391 More...

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 6

multiple interactions
increases expression

ATF6 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]
deoxynivalenol results in increased expression of ATF6 protein
deoxynivalenol results in increased expression of ATF6 mRNA

PMID:19336499 PMID:20682335 PMID:22846391

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

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autophagy related 14

increases expression

deoxynivalenol results in increased expression of ATG14 mRNA

NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113

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autophagy related 4B, cysteine peptidase

increases expression

deoxynivalenol results in increased expression of ATG4B mRNA

NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103

G

autophagy related 5

increases expression
multiple interactions

deoxynivalenol results in increased expression of ATG5 mRNA; deoxynivalenol results in increased expression of ATG5 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of ATG5 protein]

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

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ATPase phospholipid transporting 10A (putative)

decreases expression

deoxynivalenol results in decreased expression of ATP10A mRNA

NCBI chr 1:109,556,760...109,730,440
Ensembl chr 1:109,556,782...109,730,437

G

ATP synthase F1 subunit gamma

decreases expression

deoxynivalenol results in decreased expression of ATP5F1C protein

NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367

G

ATP synthase peripheral stalk subunit d

decreases expression

deoxynivalenol results in decreased expression of ATP5PD protein

NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479

G

ATPase H+ transporting V1 subunit A

decreases expression

deoxynivalenol results in decreased expression of ATP6V1A protein

NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694

G

ATPase H+ transporting V1 subunit B2

decreases expression

deoxynivalenol results in decreased expression of ATP6V1B2 protein

NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745

G

ATPase H+ transporting V1 subunit D

decreases expression

deoxynivalenol results in decreased expression of ATP6V1D protein

NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303

G

ATPase H+ transporting V1 subunit G1

decreases expression

deoxynivalenol results in decreased expression of ATP6V1G1 protein

NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463

G

ATPase H+ transporting V1 subunit H

decreases expression

deoxynivalenol results in decreased expression of ATP6V1H protein

NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962

G

ATPase phospholipid transporting 8B2

decreases expression

deoxynivalenol results in decreased expression of ATP8B2 mRNA

NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:175,378,517...175,401,883

G

ATRX, chromatin remodeler

affects phosphorylation

deoxynivalenol affects the phosphorylation of ATRX protein

NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330

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Beta-1,3-galactosyltransferase 4

decreases expression

deoxynivalenol results in decreased expression of B3GALT4 mRNA

NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315

G

BTB domain and CNC homolog 2

increases expression

deoxynivalenol results in increased expression of BACH2 mRNA

NCBI chr 5:46,632,338...46,982,676
Ensembl chr 5:46,638,317...46,977,877

G

BCL2-associated agonist of cell death

increases phosphorylation

deoxynivalenol results in increased phosphorylation of BAD protein

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

BAG cochaperone 3

increases expression

deoxynivalenol results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BCL2-antagonist/killer 1

increases expression

deoxynivalenol results in increased expression of BAK1 mRNA

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

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BCL2 associated X, apoptosis regulator

multiple interactions
increases expression
affects localization
decreases expression

[Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX mRNA; [Zearalenone co-treated with deoxynivalenol] results in increased expression of BAX protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]
Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of BAX mRNA]
deoxynivalenol results in increased expression of BAX mRNA; deoxynivalenol results in increased expression of BAX protein
deoxynivalenol affects the localization of BAX protein
deoxynivalenol results in decreased expression of BAX mRNA

PMID:15976193 PMID:17166419 PMID:19410639 PMID:22269384 PMID:25445755 More...

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

increases expression

deoxynivalenol results in increased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

BCL10, immune signaling adaptor

increases expression

deoxynivalenol results in increased expression of BCL10 mRNA

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

G

BCL2, apoptosis regulator

multiple interactions
decreases expression
increases expression

Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]
deoxynivalenol results in decreased expression of BCL2 mRNA; deoxynivalenol results in decreased expression of BCL2 protein
Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in decreased expression of BCL2 mRNA]
deoxynivalenol results in increased expression of BCL2 mRNA

PMID:17166419 PMID:22269384 PMID:25445755 PMID:35817260

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression

deoxynivalenol results in decreased expression of BCL2L1 mRNA

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

Bcl2-like 13

increases expression

deoxynivalenol results in increased expression of BCL2L13 mRNA

NCBI chr 4:154,056,116...154,112,890
Ensembl chr 4:154,056,127...154,108,985

G

BCL6, transcription repressor

increases expression

deoxynivalenol results in increased expression of BCL6 mRNA

PMID:22968694 PMID:31863870

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

BCL2-associated transcription factor 1

increases expression
affects phosphorylation

deoxynivalenol results in increased expression of BCLAF1 mRNA
deoxynivalenol affects the phosphorylation of BCLAF1 protein

PMID:22846391 PMID:23352502 PMID:23811945

NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832

G

beclin 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of BECN1 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of BECN1 mRNA]

PMID:34677630 PMID:35381244

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

BEN domain containing 7

increases expression

deoxynivalenol results in increased expression of BEND7 mRNA

NCBI chr17:73,483,212...73,566,221
Ensembl chr17:73,485,282...73,567,559

G

BH3 interacting domain death agonist

decreases expression

deoxynivalenol results in decreased expression of BID mRNA

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

bridging integrator 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of BIN1 protein

NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263

G

basic helix-loop-helix ARNT like 1

multiple interactions

BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GOT1 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of CLOCK protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of NR1D1 protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER2 protein]; BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER3 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CLOCK mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER3 mRNA]

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

G

bone morphogenetic protein 2

increases expression

deoxynivalenol results in increased expression of BMP2 mRNA

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

G

BCL2 interacting protein 1

increases expression

deoxynivalenol results in increased expression of BNIP1 mRNA

NCBI chr10:16,386,876...16,399,124
Ensembl chr10:16,386,841...16,399,157

G

BCL2 interacting protein 2

increases phosphorylation

deoxynivalenol results in increased phosphorylation of BNIP2 protein

NCBI chr 8:70,640,436...70,661,782
Ensembl chr 8:70,640,445...70,675,590

G

bromodomain PHD finger transcription factor

increases phosphorylation

deoxynivalenol results in increased phosphorylation of BPTF protein

NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769

G

bromodomain containing 3

increases phosphorylation

deoxynivalenol results in increased phosphorylation of BRD3 protein

NCBI chr 3:10,773,163...10,829,675
Ensembl chr 3:10,775,272...10,829,577

G

bone marrow stromal cell antigen 1

decreases expression

deoxynivalenol results in decreased expression of BST1 mRNA

NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180

G

BUB1 mitotic checkpoint serine/threonine kinase B

increases expression

deoxynivalenol results in increased expression of BUB1B mRNA

NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547

G

BUB3 mitotic checkpoint protein

increases expression

deoxynivalenol results in increased expression of BUB3 mRNA

NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036

G

complement C3

increases expression

deoxynivalenol results in increased expression of C3 mRNA

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

complement C3a receptor 1

increases expression

deoxynivalenol results in increased expression of C3AR1 mRNA

PMID:12604170 PMID:22968694

NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701

G

complement C4B

increases expression

deoxynivalenol results in increased expression of C4B mRNA

NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681

G

calcium voltage-gated channel subunit alpha1 D

increases expression

deoxynivalenol results in increased expression of CACNA1D mRNA

NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215

G

calcium voltage-gated channel auxiliary subunit gamma 6

decreases expression

deoxynivalenol results in decreased expression of CACNG6 mRNA

NCBI chr 1:65,732,910...65,747,377
Ensembl chr 1:65,732,632...65,747,341

G

calnexin

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of CANX protein

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

G

caspase recruitment domain family, member 11

affects phosphorylation

deoxynivalenol affects the phosphorylation of CARD11 protein

NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112

G

CASC3 exon junction complex subunit

increases phosphorylation

deoxynivalenol results in increased phosphorylation of CASC3 protein

NCBI chr10:83,769,014...83,788,966
Ensembl chr10:83,769,001...83,788,966

G

caspase 1

increases expression
increases cleavage
multiple interactions

deoxynivalenol results in increased expression of CASP1 mRNA
deoxynivalenol results in increased cleavage of CASP1 protein
deoxynivalenol promotes the reaction [fumonisin B1 results in increased cleavage of CASP1 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased cleavage of CASP1 protein]

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 3

increases activity
increases expression
multiple interactions
increases cleavage
decreases expression

deoxynivalenol results in increased activity of CASP3 protein
deoxynivalenol results in increased expression of CASP3 mRNA; deoxynivalenol results in increased expression of CASP3 protein
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]
deoxynivalenol results in increased cleavage of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [deoxynivalenol results in increased activity of CASP3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]; deoxynivalenol results in increased activity of and results in increased cleavage of CASP3 protein; deoxynivalenol results in increased expression of and results in increased cleavage of CASP3 protein; HCK protein affects the reaction [deoxynivalenol results in increased activity of CASP3 protein]; lauric acid inhibits the reaction [deoxynivalenol results in increased cleavage of CASP3 protein]; pifithrin inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased activity of CASP3 protein]; Zearalenone promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]
deoxynivalenol results in decreased expression of CASP3 protein
[Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; [Zearalenone co-treated with deoxynivalenol] results in increased expression of CASP3 protein; Aflatoxin B1 promotes the reaction [deoxynivalenol results in increased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of CASP3 protein

PMID:15772366 PMID:15976193 PMID:17166419 PMID:19410639 PMID:19664677 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 7

increases activity

deoxynivalenol results in increased activity of CASP7 protein

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

increases expression
multiple interactions

deoxynivalenol results in increased expression of CASP8 mRNA
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP8 mRNA]
[Aflatoxin B1 co-treated with deoxynivalenol] promotes the reaction [Zearalenone results in increased expression of CASP8 mRNA]; [Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA; [Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of CASP8 mRNA]; [Zearalenone co-treated with deoxynivalenol] promotes the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA]; Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP8 mRNA]
deoxynivalenol results in increased activity of and results in increased cleavage of CASP8 protein

PMID:22491426 PMID:22846391 PMID:30668976 PMID:34673182

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

decreases expression
multiple interactions
increases expression
increases activity

deoxynivalenol results in decreased expression of CASP9 protein
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CASP9 mRNA]
Zearalenone promotes the reaction [[Aflatoxin B1 co-treated with deoxynivalenol] results in increased expression of CASP9 mRNA]
deoxynivalenol results in increased activity of and results in increased cleavage of CASP9 protein
deoxynivalenol results in increased expression of CASP9 mRNA; deoxynivalenol results in increased expression of CASP9 protein
deoxynivalenol results in increased activity of CASP9 protein

PMID:22269384 PMID:22491426 PMID:30668976 PMID:34673182 PMID:35314294

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

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calcium-sensing receptor

multiple interactions

CASR affects the reaction [deoxynivalenol results in increased secretion of CCK protein]

NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811

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catalase

increases expression
multiple interactions
decreases expression
increases activity
decreases activity

deoxynivalenol results in increased expression of CAT mRNA; deoxynivalenol results in increased expression of CAT protein
Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CAT mRNA]
deoxynivalenol results in increased activity of CAT protein
deoxynivalenol results in decreased activity of CAT protein
Lutein inhibits the reaction [deoxynivalenol results in increased expression of CAT protein]

PMID:20347963 PMID:34400200 PMID:34673182 PMID:35314294 PMID:35817260

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

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Cbl proto-oncogene like 1

increases expression

deoxynivalenol results in increased expression of CBLL1 mRNA

NCBI chr 6:48,071,190...48,086,174
Ensembl chr 6:48,071,190...48,086,444

G

cystathionine beta synthase

decreases expression

deoxynivalenol results in decreased expression of CBS mRNA

NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764

G

chromobox 5

increases phosphorylation

deoxynivalenol results in increased phosphorylation of CBX5 protein

NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022

G

coiled-coil domain containing 112

increases expression

deoxynivalenol results in increased expression of CCDC112 mRNA

NCBI chr18:38,998,139...39,032,329
Ensembl chr18:38,998,139...39,032,329

G

cholecystokinin

increases secretion
multiple interactions
increases expression

deoxynivalenol results in increased secretion of CCK protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; 2-aminoethyl diphenylborinate inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; [N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine co-treated with Ruthenium Red] inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; CASR affects the reaction [deoxynivalenol results in increased secretion of CCK protein]; Egtazic Acid inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; Nitrendipine inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; Ruthenium Red inhibits the reaction [deoxynivalenol results in increased expression of CCK protein]; triphenylphosphine oxide inhibits the reaction [deoxynivalenol results in increased secretion of CCK protein]; TRPA1 affects the reaction [deoxynivalenol results in increased secretion of CCK protein]

PMID:22903826 PMID:24385417 PMID:25787141 PMID:26979077

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

C-C motif chemokine ligand 1

increases expression

deoxynivalenol results in increased expression of CCL1 mRNA

NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159

G

C-C motif chemokine ligand 11

increases expression

deoxynivalenol results in increased expression of CCL11 mRNA

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

G

C-C motif chemokine ligand 12

increases expression

deoxynivalenol results in increased expression of CCL12 mRNA

NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780

G

C-C motif chemokine ligand 17

increases expression

deoxynivalenol results in increased expression of CCL17 mRNA

NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819

G

C-C motif chemokine ligand 2

increases expression
multiple interactions

deoxynivalenol results in increased expression of CCL2 mRNA; deoxynivalenol results in increased expression of CCL2 protein
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL2 mRNA]

PMID:15371230 PMID:15681167 PMID:17090620 PMID:22846391 PMID:22968694 More...

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

increases expression

deoxynivalenol results in increased expression of CCL20 mRNA

PMID:27757495 PMID:35314294

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 22

increases expression

deoxynivalenol results in increased expression of CCL22 mRNA

NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400

G

C-C motif chemokine ligand 24

increases expression

deoxynivalenol results in increased expression of CCL24 mRNA

NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893

G

C-C motif chemokine ligand 25

decreases expression

deoxynivalenol results in decreased expression of CCL25 mRNA

NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554

G

C-C motif chemokine ligand 3

increases expression

deoxynivalenol results in increased expression of CCL3 mRNA

PMID:22846391 PMID:22968694

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 4

increases expression

deoxynivalenol results in increased expression of CCL4 mRNA

PMID:21074547 PMID:22846391 PMID:22968694 PMID:27757495

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

C-C motif chemokine ligand 5

increases expression
multiple interactions

deoxynivalenol results in increased expression of CCL5 mRNA
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CCL5 mRNA]

PMID:22968694 PMID:27757495 PMID:35925383

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 7

multiple interactions
increases expression

Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CCL7 mRNA]

PMID:15371230 PMID:15681167 PMID:22968694 PMID:24793808

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

cellular communication network factor 1

increases expression

deoxynivalenol results in increased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cellular communication network factor 2

increases expression

deoxynivalenol results in increased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin B1

increases expression
multiple interactions

deoxynivalenol results in increased expression of CCNB1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CCNB1 mRNA]

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin D1

increases expression
multiple interactions

deoxynivalenol results in increased expression of CCND1 mRNA; deoxynivalenol results in increased expression of CCND1 protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of CCND1 protein]

PMID:22454431 PMID:24937323 PMID:32416088

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin E1

decreases expression

deoxynivalenol results in decreased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin G2

increases expression

deoxynivalenol results in increased expression of CCNG2 mRNA

NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830

G

cyclin Y

affects phosphorylation

deoxynivalenol affects the phosphorylation of CCNY protein

NCBI chr17:57,385,002...57,512,860
Ensembl chr17:57,384,176...57,522,378

G

C-C motif chemokine receptor 1

increases expression

deoxynivalenol results in increased expression of CCR1 mRNA

NCBI chr 8:123,556,286...123,561,841

G

C-C motif chemokine receptor 2

increases expression

deoxynivalenol results in increased expression of CCR2 mRNA

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

G

C-C motif chemokine receptor 3

increases expression

deoxynivalenol results in increased expression of CCR3 mRNA

NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990

G

C-C motif chemokine receptor 4

increases expression

deoxynivalenol results in increased expression of CCR4 mRNA

NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056

G

C-C motif chemokine receptor 7

increases expression

deoxynivalenol results in increased expression of CCR7 mRNA

NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309

G

CD14 molecule

multiple interactions

deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein]

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

CD248 molecule

decreases expression

deoxynivalenol results in decreased expression of CD248 mRNA

NCBI chr 1:202,373,676...202,376,240
Ensembl chr 1:202,373,676...202,376,240

G

CD40 molecule

decreases expression

deoxynivalenol results in decreased expression of CD40 mRNA

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

G

CD55 molecule (Cromer blood group)

increases expression

deoxynivalenol results in increased expression of CD55 mRNA

PMID:22846391 PMID:24247028

NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831

G

Cd68 molecule

increases expression

deoxynivalenol results in increased expression of CD68 mRNA

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

Cd69 molecule

increases expression

deoxynivalenol results in increased expression of CD69 mRNA

PMID:22846391 PMID:24247028

NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542

G

Cd80 molecule

increases expression

deoxynivalenol results in increased expression of CD80 mRNA

NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030

G

CD86 molecule

increases expression

deoxynivalenol results in increased expression of CD86 mRNA

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

G

codanin 1

increases expression

deoxynivalenol results in increased expression of CDAN1 mRNA

NCBI chr 3:107,675,147...107,689,811
Ensembl chr 3:107,673,645...107,689,773

G

cadherin 13

decreases expression

deoxynivalenol results in decreased expression of CDH13 mRNA

NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459

G

cyclin-dependent kinase 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of CDK1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CDK1 mRNA]

PMID:31863870 PMID:34677630

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions
decreases degradation

deoxynivalenol results in increased expression of CDKN1A mRNA; deoxynivalenol results in increased expression of CDKN1A protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CDKN1A mRNA]; EGR1 protein affects the reaction [deoxynivalenol results in increased expression of CDKN1A protein]; U 0126 inhibits the reaction [deoxynivalenol results in decreased degradation of CDKN1A mRNA]

PMID:18006205 PMID:22454431 PMID:30169763 PMID:30286430 PMID:31863870 More...

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 3

increases expression

deoxynivalenol results in increased expression of CDKN3 mRNA

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

CCAAT/enhancer binding protein alpha

multiple interactions
decreases expression

[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CEBPA mRNA
deoxynivalenol results in decreased expression of CEBPA mRNA

PMID:28865950 PMID:28935499

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

CCAAT/enhancer binding protein beta

multiple interactions
increases activity
affects localization

4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of CEBPB protein]
deoxynivalenol affects the localization of CEBPB protein

PMID:12604842 PMID:15772366

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

centromere protein W

increases expression

deoxynivalenol results in increased expression of CENPW mRNA

NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464

G

cerebral endothelial cell adhesion molecule

decreases expression

deoxynivalenol results in decreased expression of CERCAM mRNA

NCBI chr 3:13,118,150...13,155,960
Ensembl chr 3:13,142,107...13,155,956

G

cell growth regulator with EF hand domain 1

decreases expression

deoxynivalenol results in decreased expression of CGREF1 mRNA

NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

decreases expression

deoxynivalenol results in decreased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

chromosome alignment maintaining phosphoprotein 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of CHAMP1 protein

NCBI chr16:75,733,958...75,744,931
Ensembl chr16:75,733,805...75,744,984

G

choline kinase alpha

increases expression

deoxynivalenol results in increased expression of CHKA mRNA

NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516

G

chimerin 1

decreases expression

deoxynivalenol results in decreased expression of CHN1 mRNA

NCBI chr 3:58,509,822...58,676,462
Ensembl chr 3:58,510,536...58,676,490

G

cysteine and histidine rich domain containing 1

increases expression

deoxynivalenol results in increased expression of CHORDC1 mRNA

NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162

G

component of inhibitor of nuclear factor kappa B kinase complex

increases phosphorylation
increases expression

deoxynivalenol results in increased phosphorylation of CHUK protein
deoxynivalenol results in increased expression of CHUK mRNA

PMID:20633634 PMID:34400200

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

cytokine inducible SH2-containing protein

increases expression

deoxynivalenol results in increased expression of CISH mRNA

NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250

G

cytoskeleton associated protein 2

increases expression

deoxynivalenol results in increased expression of CKAP2 mRNA

NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913

G

cytoskeleton associated protein 5

increases expression

deoxynivalenol results in increased expression of CKAP5 mRNA

NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264

G

CDC28 protein kinase regulatory subunit 1B

increases expression

deoxynivalenol results in increased expression of CKS1B mRNA

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

claudin 1

increases expression
decreases expression
multiple interactions
affects expression

deoxynivalenol results in increased expression of CLDN1 mRNA
deoxynivalenol results in decreased expression of CLDN1 mRNA; deoxynivalenol results in decreased expression of CLDN1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of CLDN1 protein]
[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CLDN1 protein; deoxynivalenol results in decreased expression of and affects the localization of CLDN1 protein
deoxynivalenol affects the expression of CLDN1 protein

PMID:24568843 PMID:28865950 PMID:28935499 PMID:34506767 PMID:35381244 More...

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 2

affects expression
increases expression

deoxynivalenol affects the expression of CLDN2 protein
deoxynivalenol results in increased expression of CLDN2 mRNA

NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838

G

claudin 3

multiple interactions
increases expression
affects expression

deoxynivalenol results in decreased expression of and affects the localization of CLDN3 protein
[deoxynivalenol results in increased susceptibility to Antigens] which results in decreased expression of CLDN3 mRNA
deoxynivalenol results in increased expression of CLDN3 mRNA
deoxynivalenol affects the expression of CLDN3 protein

PMID:24568843 PMID:28935500

NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001

G

claudin 4

decreases expression
increases expression
multiple interactions

deoxynivalenol results in decreased expression of CLDN4 protein
deoxynivalenol results in increased expression of CLDN4 mRNA
deoxynivalenol results in decreased expression of and affects the localization of CLDN4 protein

PMID:19289138 PMID:20362602 PMID:24568843

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

chloride intracellular channel 3

decreases expression

deoxynivalenol results in decreased expression of CLIC3 mRNA

NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018

G

clock circadian regulator

multiple interactions
decreases expression

BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of CLOCK protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CLOCK mRNA]

NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400

G

canopy FGF signaling regulator 2

decreases expression

deoxynivalenol results in decreased expression of CNPY2 mRNA

NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519

G

collagen type XV alpha 1 chain

decreases expression

deoxynivalenol results in decreased expression of COL15A1 mRNA

NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591

G

collagen type IV alpha 1 chain

decreases expression

deoxynivalenol results in decreased expression of COL4A1 mRNA

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen type V alpha 1 chain

decreases expression

deoxynivalenol results in decreased expression of COL5A1 mRNA

NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588

G

collagen type VI alpha 2 chain

decreases expression

deoxynivalenol results in decreased expression of COL6A2 mRNA

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

catechol-O-methyltransferase

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of COMT protein

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

coronin 1A

affects phosphorylation

deoxynivalenol affects the phosphorylation of CORO1A protein

NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534

G

coronin 2B

decreases expression

deoxynivalenol results in decreased expression of CORO2B mRNA

NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302

G

cytochrome c oxidase subunit 5B

decreases expression

deoxynivalenol results in decreased expression of COX5B protein

NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052

G

cleavage and polyadenylation specific factor 2

increases expression

deoxynivalenol results in increased expression of CPSF2 mRNA

NCBI chr 6:121,123,941...121,152,756
Ensembl chr 6:121,120,569...121,151,921

G

cAMP responsive element binding protein 1

multiple interactions
increases phosphorylation
increases activity
affects localization

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; AKT1 protein affects the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased activity of CREB1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein]
deoxynivalenol affects the localization of CREB1 protein

PMID:12604842 PMID:16424113 PMID:32416088

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cAMP responsive element binding protein 5

increases expression

deoxynivalenol results in increased expression of CREB5 mRNA

NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325

G

CREB binding protein

increases expression

deoxynivalenol results in increased expression of CREBBP mRNA

NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888

G

cysteine-rich with EGF-like domains 1

decreases expression

deoxynivalenol results in decreased expression of CRELD1 mRNA

NCBI chr 4:146,631,883...146,641,493
Ensembl chr 4:146,631,883...146,641,499

G

C-reactive protein

increases expression

deoxynivalenol results in increased expression of CRP mRNA

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

cryptochrome circadian regulator 1

multiple interactions

deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY1 protein]

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

cryptochrome circadian regulator 2

multiple interactions

deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of CRY2 protein]

NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965

G

colony stimulating factor 3

increases expression

deoxynivalenol results in increased expression of CSF3 mRNA

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

collagen triple helix repeat containing 1

decreases expression

deoxynivalenol results in decreased expression of CTHRC1 mRNA

NCBI chr 7:70,122,474...70,132,756
Ensembl chr 7:70,122,474...70,132,756

G

catenin alpha 1

decreases expression

deoxynivalenol results in decreased expression of CTNNA1 protein

NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910

G

catenin beta 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of CTNNB1 protein

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

cathepsin O

decreases expression

deoxynivalenol results in decreased expression of CTSO mRNA

NCBI chr 2:167,230,407...167,254,761
Ensembl chr 2:167,230,330...167,253,702

G

CWF19 like cell cycle control factor 2

increases expression

deoxynivalenol results in increased expression of CWF19L2 mRNA

NCBI chr 6:290,148...356,636
Ensembl chr 6:281,685...356,604

G

C-X3-C motif chemokine ligand 1

increases expression

deoxynivalenol results in increased expression of CX3CL1 mRNA

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

G

C-X-C motif chemokine ligand 1

multiple interactions
increases expression

[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]

PMID:22003189 PMID:27757495

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 10

decreases expression
increases expression

deoxynivalenol results in decreased expression of CXCL10 mRNA
deoxynivalenol results in increased expression of CXCL10 mRNA; deoxynivalenol results in increased expression of CXCL10 protein

PMID:15371230 PMID:22968694 PMID:34400200

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 11

decreases expression
increases expression

deoxynivalenol results in decreased expression of CXCL11 mRNA
deoxynivalenol results in increased expression of CXCL11 mRNA

PMID:22968694 PMID:27757495

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

G

C-X-C motif chemokine ligand 2

increases expression
multiple interactions

deoxynivalenol results in increased expression of CXCL2 mRNA; deoxynivalenol results in increased expression of CXCL2 protein
deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA]; Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of CXCL2 mRNA]

PMID:12604170 PMID:15371230 PMID:15681167 PMID:22968694 PMID:24793808 More...

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

multiple interactions
increases expression

[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]
deoxynivalenol results in increased expression of CXCL1 mRNA; deoxynivalenol results in increased expression of CXCL3 mRNA

PMID:15371230 PMID:15681167 PMID:22003189 PMID:22968694 PMID:27757495

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 9

increases expression

deoxynivalenol results in increased expression of CXCL9 mRNA

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

C-X-C motif chemokine receptor 1

increases expression

deoxynivalenol results in increased expression of CXCR1 mRNA

NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084

G

C-X-C motif chemokine receptor 2

increases expression

deoxynivalenol results in increased expression of CXCR2 mRNA

NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425

G

C-X-C motif chemokine receptor 4

increases expression

deoxynivalenol results in increased expression of CXCR4 mRNA

PMID:22846391 PMID:27757495

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

G

cytochrome c-1

decreases expression

deoxynivalenol results in decreased expression of CYC1 protein

NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479

G

cytochrome c, somatic

affects localization
increases expression
decreases expression
increases activity

deoxynivalenol affects the localization of CYCS protein
deoxynivalenol results in increased expression of CYCS mRNA; deoxynivalenol results in increased expression of CYCS protein
deoxynivalenol results in decreased expression of CYCS protein
deoxynivalenol results in increased activity of CYCS protein

PMID:15976193 PMID:22269384 PMID:22846391

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 11, subfamily b, polypeptide 2

increases expression

deoxynivalenol results in increased expression of CYP11B1 mRNA

NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004

G

cytochrome P450, family 11, subfamily b, polypeptide 3

increases expression

deoxynivalenol results in increased expression of CYP11B2 mRNA

NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

deoxynivalenol results in increased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases expression

deoxynivalenol results in decreased expression of CYP19A1 mRNA

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of CYP1A1 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of CYP1A1 mRNA]

PMID:22982764 PMID:35381244

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases expression

deoxynivalenol results in decreased expression of CYP1B1 mRNA

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 3, subfamily a, polypeptide 2

affects expression
multiple interactions

deoxynivalenol affects the expression of CYP3A4 mRNA
[deoxynivalenol co-treated with Zearalenone] affects the expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP3A4 protein; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP3A4 protein

PMID:28865950 PMID:28935499

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily f, polypeptide 18

multiple interactions

[deoxynivalenol co-treated with Zearalenone] results in decreased expression of CYP4F3 mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of CYP4F3 mRNA

PMID:28865950 PMID:28935499

NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940

G

cytokine like 1

decreases expression

deoxynivalenol results in decreased expression of CYTL1 mRNA

NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886

G

damage specific DNA binding protein 2

increases expression

deoxynivalenol results in increased expression of DDB2 mRNA

NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631

G

DNA-damage inducible transcript 3

increases expression
decreases expression

deoxynivalenol results in increased expression of DDIT3 mRNA
deoxynivalenol results in decreased expression of DDIT3 mRNA

PMID:22846391 PMID:23253260 PMID:30169763

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

decreases expression

deoxynivalenol results in decreased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

DExD-box helicase 21

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of DDX21 protein

PMID:23352502 PMID:23811945

NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543

G

DExD-box helicase 39A

increases expression

deoxynivalenol results in increased expression of DDX39A mRNA

NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954

G

DExD-box helicase 52

increases expression

deoxynivalenol results in increased expression of DDX52 mRNA

NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266

G

DEP domain containing MTOR-interacting protein

decreases expression

deoxynivalenol results in decreased expression of DEPTOR mRNA

NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773

G

DNA fragmentation factor subunit alpha

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of DFFA protein

NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633

G

dyskerin pseudouridine synthase 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of DKC1 protein

G

dynein, axonemal, heavy chain 10

affects phosphorylation

deoxynivalenol affects the phosphorylation of DNAH10 protein

NCBI chr12:31,823,451...31,946,857
Ensembl chr12:31,822,733...32,007,069

G

DnaJ heat shock protein family (Hsp40) member A1

increases expression
decreases expression

deoxynivalenol results in increased expression of DNAJA1 mRNA
deoxynivalenol results in decreased expression of DNAJA1 protein

PMID:15371230 PMID:33890134

NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967

G

DnaJ heat shock protein family (Hsp40) member C1

increases expression

deoxynivalenol results in increased expression of DNAJC1 mRNA

NCBI chr17:80,955,209...81,112,025
Ensembl chr17:80,955,237...81,111,988

G

DnaJ heat shock protein family (Hsp40) member C3

multiple interactions
decreases expression

deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA]
deoxynivalenol results in decreased expression of DNAJC3 mRNA

NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181

G

DnaJ heat shock protein family (Hsp40) member C5

increases phosphorylation

deoxynivalenol results in increased phosphorylation of DNAJC5 protein

NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935

G

DNA methyltransferase 1

affects phosphorylation
increases expression

deoxynivalenol affects the phosphorylation of DNMT1 protein
deoxynivalenol results in increased expression of DNMT1 mRNA; deoxynivalenol results in increased expression of DNMT1 protein

PMID:23352502 PMID:23811945 PMID:32738333

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

increases expression

deoxynivalenol results in increased expression of DNMT3A mRNA; deoxynivalenol results in increased expression of DNMT3A protein

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

deoxynucleotidyltransferase, terminal, interacting protein 2

increases expression

deoxynivalenol results in increased expression of DNTTIP2 mRNA

NCBI chr 2:210,374,321...210,386,366
Ensembl chr 2:210,374,289...210,385,581

G

desmocollin 1

increases expression

deoxynivalenol results in increased expression of DSC1 protein

NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494

G

dual specificity phosphatase 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of DUSP1 mRNA; deoxynivalenol results in increased expression of DUSP1 protein
Fatty Acids, Omega-3 promotes the reaction [deoxynivalenol results in increased expression of DUSP1 mRNA]
[deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein; [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK9 protein

PMID:15371230 PMID:15681167 PMID:20708668

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 6

decreases expression

deoxynivalenol results in decreased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dual specificity phosphatase 8

increases expression

deoxynivalenol results in increased expression of DUSP8 mRNA

NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921

G

dynein cytoplasmic 1 light intermediate chain 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of DYNC1LI1 protein

NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934

G

extracellular matrix protein 1

decreases expression

deoxynivalenol results in decreased expression of ECM1 mRNA

NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671

G

epithelial cell transforming 2

increases expression

deoxynivalenol results in increased expression of ECT2 mRNA

NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911

G

eukaryotic translation elongation factor 1 beta 2

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of EEF1B2 protein

NCBI chr 9:64,580,163...64,582,737
Ensembl chr 9:64,579,893...64,582,737

G

eukaryotic translation elongation factor 1 delta

increases phosphorylation

deoxynivalenol results in increased phosphorylation of EEF1D protein

NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799

G

epidermal growth factor

increases expression

deoxynivalenol results in increased expression of EGF mRNA

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

decreases expression

deoxynivalenol results in decreased expression of EGFR protein

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

early growth response 1

increases expression
multiple interactions

[deoxynivalenol results in increased expression of EGR1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased expression of EGR1 mRNA; deoxynivalenol results in increased expression of EGR1 protein
ATF3 protein affects the reaction [deoxynivalenol results in increased expression of EGR1 protein]; deoxynivalenol results in increased expression of and results in increased phosphorylation of EGR1 protein; EGR1 protein affects the reaction [deoxynivalenol results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]

PMID:17707346 PMID:18485432 PMID:19360757 PMID:30286430 PMID:33890134

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

EP300 interacting inhibitor of differentiation 2

increases expression

deoxynivalenol results in increased expression of EID2 mRNA

NCBI chr 1:83,538,274...83,539,599

G

eukaryotic translation initiation factor 2A

increases phosphorylation

deoxynivalenol results in increased phosphorylation of EIF2A protein

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

eukaryotic translation initiation factor 2-alpha kinase 2

decreases expression
affects response to substance
multiple interactions

deoxynivalenol results in decreased expression of EIF2AK2 mRNA
EIF2AK2 protein affects the susceptibility to deoxynivalenol
EIF2AK2 protein affects the reaction [deoxynivalenol results in increased activity of RELA protein]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]

PMID:17090620 PMID:18599499 PMID:22491426

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

G

eukaryotic translation initiation factor 2B subunit delta

increases expression

deoxynivalenol results in increased expression of EIF2B4 mRNA

NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829

G

eukaryotic translation initiation factor 2 subunit beta

affects expression

deoxynivalenol affects the expression of EIF2S2 mRNA

NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432

G

eukaryotic translation initiation factor 3, subunit B

affects phosphorylation

deoxynivalenol affects the phosphorylation of EIF3B protein

NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886

G

eukaryotic translation initiation factor 3, subunit C

affects phosphorylation

deoxynivalenol affects the phosphorylation of EIF3C protein

NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493

G

eukaryotic translation initiation factor 4E binding protein 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of EIF4EBP1 protein

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

eukaryotic translation initiation factor 4 gamma 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of EIF4G1 protein

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

G

eukaryotic translation initiation factor 5B

affects phosphorylation

deoxynivalenol affects the phosphorylation of EIF5B protein

NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482

G

ELAV like RNA binding protein 1

multiple interactions

[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the localization of ELAVL1 protein; [deoxynivalenol results in increased expression of ELAVL1 protein] which results in decreased degradation of CXCL8 mRNA; deoxynivalenol results in increased expression of and results in increased localization of ELAVL1 protein; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ELAVL1 protein affects the reaction [deoxynivalenol results in increased expression of CXCL8 protein]

PMID:19591856 PMID:22003189

NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784

G

ETS transcription factor ELK1

increases expression

deoxynivalenol results in increased expression of ELK1 protein

NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713

G

ER membrane protein complex subunit 10

decreases expression

deoxynivalenol results in decreased expression of EMC10 mRNA

NCBI chr 1:94,980,260...94,988,847
Ensembl chr 1:94,943,587...94,988,847

G

elastin microfibril interfacer 1

decreases expression

deoxynivalenol results in decreased expression of EMILIN1 mRNA

NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698

G

endoglin

decreases expression

deoxynivalenol results in decreased expression of ENG mRNA

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

G

endo-beta-N-acetylglucosaminidase

increases expression

deoxynivalenol results in increased expression of ENGASE mRNA

NCBI chr10:103,707,169...103,719,833
Ensembl chr10:103,707,169...103,719,819

G

E1A binding protein p300

multiple interactions
increases expression

EP300 protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]
deoxynivalenol results in increased expression of EP300 protein

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

E1A binding protein p400

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of EP400 protein

NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861

G

erythrocyte membrane protein band 4.1-like 2

affects phosphorylation

deoxynivalenol affects the phosphorylation of EPB41L2 protein

NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721

G

epoxide hydrolase 1

decreases expression

deoxynivalenol results in decreased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

endoplasmic reticulum to nucleus signaling 1

decreases expression
increases expression

deoxynivalenol results in decreased expression of ERN1 mRNA
deoxynivalenol results in increased expression of ERN1 protein

PMID:19336499 PMID:20682335

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

estrogen receptor 1

multiple interactions
increases phosphorylation

ESR1 promotes the reaction [deoxynivalenol results in increased expression of PGR mRNA]; ESR1 promotes the reaction [deoxynivalenol results in increased expression of TFF1 mRNA]
deoxynivalenol results in increased phosphorylation of ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

ethanolamine kinase 1

increases expression

deoxynivalenol results in increased expression of ETNK1 mRNA

NCBI chr 4:176,126,056...176,170,325
Ensembl chr 4:176,126,180...176,193,770

G

ecotropic viral integration site 2A

increases expression

deoxynivalenol results in increased expression of EVI2A mRNA

NCBI chr10:64,485,760...64,489,660
Ensembl chr10:64,485,200...64,489,843

G

Enah/Vasp-like

affects phosphorylation

deoxynivalenol affects the phosphorylation of EVL protein

NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344

G

exosome component 2

increases expression

deoxynivalenol results in increased expression of EXOSC2 mRNA

NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575

G

coagulation factor III, tissue factor

decreases expression

deoxynivalenol results in decreased expression of F3 mRNA

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

fatty acid binding protein 3

decreases expression

deoxynivalenol results in decreased expression of FABP3 mRNA

NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718

G

fatty acid binding protein 4

decreases expression

deoxynivalenol results in decreased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid binding protein 6

decreases expression

deoxynivalenol results in decreased expression of FABP6 mRNA

NCBI chr10:28,063,603...28,068,276
Ensembl chr10:28,063,603...28,068,282

G

family with sequence similarity 83, member D

increases expression

deoxynivalenol results in increased expression of FAM83D mRNA

NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192

G

Fas cell surface death receptor

multiple interactions
increases expression

Bentonite inhibits the reaction [deoxynivalenol results in increased expression of FAS protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of FAS protein]
deoxynivalenol results in increased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

increases expression

deoxynivalenol results in increased expression of FASL mRNA

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

FAST kinase domains 2

increases expression

deoxynivalenol results in increased expression of FASTKD2 mRNA

NCBI chr 9:65,166,148...65,188,184
Ensembl chr 9:65,168,228...65,188,174

G

F-box protein 22

increases expression

deoxynivalenol results in increased expression of FBXO22 mRNA

NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148

G

F-box protein 28

increases expression

deoxynivalenol results in increased expression of FBXO28 mRNA

NCBI chr13:93,995,993...94,021,464
Ensembl chr13:93,995,996...94,021,464

G

farnesyl diphosphate farnesyl transferase 1

decreases expression

deoxynivalenol results in decreased expression of FDFT1 protein

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

decreases expression

deoxynivalenol results in decreased expression of FDPS protein

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

filamin A

decreases phosphorylation
increases phosphorylation

deoxynivalenol results in decreased phosphorylation of FLNA protein
deoxynivalenol results in increased phosphorylation of FLNA protein

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

formin-like 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of FMNL1 protein

NCBI chr10:88,115,876...88,143,342
Ensembl chr10:88,116,009...88,143,357

G

fibromodulin

decreases expression

deoxynivalenol results in decreased expression of FMOD mRNA

NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133

G

fibronectin 1

decreases expression

deoxynivalenol results in decreased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

formin binding protein 1

decreases expression

deoxynivalenol results in decreased expression of FNBP1 mRNA

NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions
affects activity

deoxynivalenol results in increased expression of FOS mRNA
deoxynivalenol inhibits the reaction [Cadmium Chloride results in decreased expression of FOS mRNA]
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of FOS protein]
deoxynivalenol affects the activity of FOS protein
deoxynivalenol results in increased expression of FOS mRNA; deoxynivalenol results in increased expression of FOS protein

PMID:10662601 PMID:15371230 PMID:15681167 PMID:19360757 PMID:21873375 More...

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FosB proto-oncogene, AP-1 transcription factor subunit

affects activity
multiple interactions
increases expression

deoxynivalenol affects the activity of FOSB protein
[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSB mRNA
deoxynivalenol results in increased expression of FOSB mRNA

PMID:10662601 PMID:33309878

NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions

[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSL1 mRNA

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

FOS like 2, AP-1 transcription factor subunit

multiple interactions
increases expression
affects activity

Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of FOSL2 mRNA]
deoxynivalenol results in increased expression of FOSL2 mRNA; deoxynivalenol results in increased expression of FOSL2 protein
[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of FOSL2 mRNA
deoxynivalenol affects the activity of FOSL2 protein

PMID:10662601 PMID:15371230 PMID:15681167 PMID:33309878 PMID:33890134

NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034

G

forkhead box O1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of FOXO1 protein

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

forkhead box P3

increases expression

deoxynivalenol results in increased expression of FOXP3 mRNA

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

G

alpha-L-fucosidase 1

decreases expression

deoxynivalenol results in decreased expression of FUCA1 mRNA

NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972

G

fucosyltransferase 1

decreases expression

deoxynivalenol results in decreased expression of FUT1 mRNA

NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616

G

G3BP stress granule assembly factor 1

decreases phosphorylation
increases phosphorylation

deoxynivalenol results in decreased phosphorylation of G3BP1 protein
deoxynivalenol results in increased phosphorylation of G3BP1 protein

PMID:23352502 PMID:23811945

NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268

G

G3BP stress granule assembly factor 2

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of G3BP2 protein

NCBI chr14:15,932,403...16,020,555
Ensembl chr14:15,987,417...16,020,548

G

GA binding protein transcription factor subunit alpha

decreases expression

deoxynivalenol results in decreased expression of GABPA protein

NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605

G

growth arrest and DNA-damage-inducible, alpha

increases expression

deoxynivalenol results in increased expression of GADD45A mRNA

PMID:30169763 PMID:31863870

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

polypeptide N-acetylgalactosaminyltransferase 1

decreases expression

deoxynivalenol results in decreased expression of GALNT1 mRNA

NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245

G

galanin-like peptide

multiple interactions
increases expression

GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL11 protein]; GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL6 protein]
deoxynivalenol results in increased expression of GALP mRNA; deoxynivalenol results in increased expression of GALP protein

NCBI chr 1:67,684,023...67,703,121
Ensembl chr 1:67,684,025...67,702,269

G

galanin receptor 2

increases expression

deoxynivalenol results in increased expression of GALR2 mRNA

NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176

G

galanin receptor 3

increases expression

deoxynivalenol results in increased expression of GALR3 mRNA

NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685

G

GATA zinc finger domain containing 2A

affects phosphorylation

deoxynivalenol affects the phosphorylation of GATAD2A protein

NCBI chr16:19,429,578...19,520,320
Ensembl chr16:19,429,578...19,519,587

G

glucagon

multiple interactions
increases expression
increases secretion

1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; 2-aminoethyl diphenylborinate inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; Egtazic Acid inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; Nitrendipine inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]; triphenylphosphine oxide inhibits the reaction [deoxynivalenol results in increased secretion of GCG protein alternative form]
deoxynivalenol results in increased expression of GCG protein

PMID:25787141 PMID:28633506

NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929

G

glutamate-cysteine ligase, catalytic subunit

decreases expression
multiple interactions

deoxynivalenol results in decreased expression of GCLC mRNA
Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GCLC protein]
Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of GCLC mRNA]

PMID:35817260 PMID:37419272

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

deoxynivalenol results in increased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

growth differentiation factor 5

increases expression

deoxynivalenol results in increased expression of GDF5 mRNA

NCBI chr 3:144,454,316...144,458,508
Ensembl chr 3:144,454,338...144,458,612

G

growth hormone 1

multiple interactions
decreases secretion
decreases expression

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; deoxynivalenol results in decreased expression of and results in decreased secretion of GH1 protein; farnesylthiosalicylic acid inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; pyrazolanthrone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; pyrazolanthrone inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of GH1 protein]
deoxynivalenol results in decreased secretion of GH1 protein

PMID:26141394 PMID:32738333 PMID:34673182

NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078

G

growth hormone receptor

affects expression

deoxynivalenol affects the expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

growth hormone releasing hormone

increases expression

deoxynivalenol results in increased expression of GHRH mRNA

NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889

G

gastric inhibitory polypeptide

increases expression

deoxynivalenol results in increased expression of GIP protein

NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503

G

G kinase anchoring protein 1

increases expression

deoxynivalenol results in increased expression of GKAP1 mRNA

NCBI chr17:6,383,963...6,423,684
Ensembl chr17:6,383,963...6,423,679

G

gliomedin

decreases expression

deoxynivalenol results in decreased expression of GLDN mRNA

NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196

G

glutamic-oxaloacetic transaminase 1

multiple interactions
increases activity

BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GOT1 protein]

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycoprotein Ib platelet subunit beta

affects phosphorylation

deoxynivalenol affects the phosphorylation of GP1BB protein

NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392

G

G patch domain and KOW motifs

increases expression

deoxynivalenol results in increased expression of GPKOW mRNA

NCBI chr X:14,791,601...14,806,384
Ensembl chr X:14,791,610...14,806,384

G

GPN-loop GTPase 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of GPN1 protein

NCBI chr 6:24,947,350...24,965,025
Ensembl chr 6:24,947,325...24,965,031

G

glutamic--pyruvic transaminase

multiple interactions
increases expression
increases activity

acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased activity of GPT protein]; deoxynivalenol promotes the reaction [Aflatoxin B1 results in increased activity of GPT protein]
Bentonite inhibits the reaction [deoxynivalenol results in increased expression of GPT protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of GPT protein]

PMID:25445755 PMID:26115597 PMID:34400200 PMID:35925383 PMID:36602574

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

increases phosphorylation
increases expression

deoxynivalenol results in increased phosphorylation of GPX1 protein
deoxynivalenol results in increased expression of GPX1 mRNA

PMID:23811945 PMID:34400200

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 4

multiple interactions
decreases expression

Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GPX4 protein]
deoxynivalenol results in decreased expression of GPX4 mRNA

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

gremlin 1, DAN family BMP antagonist

decreases expression

deoxynivalenol results in decreased expression of GREM1 mRNA

NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082

G

gasdermin D

increases expression
multiple interactions

deoxynivalenol results in increased expression of GSDMD mRNA; deoxynivalenol results in increased expression of GSDMD protein
deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD protein]; deoxynivalenol results in increased expression of and results in increased cleavage of GSDMD protein; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of GSDMD mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of GSDMD protein]

PMID:35925383 PMID:36309173

NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055

G

gasdermin E

multiple interactions

acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein]; deoxynivalenol results in increased expression of and results in increased cleavage of GSDME protein
[GSDME protein co-treated with deoxynivalenol] results in increased secretion of IL1B protein; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of GSDME protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of GSDME protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of GSDME protein; GSDME protein inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein]; GSDME protein promotes the reaction [deoxynivalenol results in increased secretion of IL6 protein]

NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806

G

glycogen synthase kinase 3 beta

increases phosphorylation

deoxynivalenol results in increased phosphorylation of GSK3B protein

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione synthetase

increases expression
multiple interactions

deoxynivalenol results in increased expression of GSS mRNA
Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of GSS protein]; Resveratrol promotes the reaction [deoxynivalenol results in increased expression of GSS protein]

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

H1.0 linker histone

increases expression

deoxynivalenol results in increased expression of H1-0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H1.10 linker histone

increases expression

deoxynivalenol results in increased expression of H1-10 mRNA

NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448

G

H1.2 linker histone, cluster member

increases expression

deoxynivalenol results in increased expression of H1-2 mRNA

NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635

G

H1.5 linker histone, cluster member

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of H1F5 protein

NCBI chr17:42,726,132...42,727,162
Ensembl chr17:42,726,127...42,769,160

G

hyaluronan and proteoglycan link protein 1

decreases expression

deoxynivalenol results in decreased expression of HAPLN1 mRNA

NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777

G

HAUS augmin like complex subunit 2

increases expression

deoxynivalenol results in increased expression of HAUS2 mRNA

NCBI chr 3:107,553,146...107,565,982
Ensembl chr 3:107,553,161...107,565,157

G

hemoglobin alpha, adult chain 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of HBA protein

NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392

G

hemoglobin subunit beta

affects phosphorylation

deoxynivalenol affects the phosphorylation of HBB-B1 protein

NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012

G

HCK proto-oncogene, Src family tyrosine kinase

increases phosphorylation
affects response to substance
multiple interactions

deoxynivalenol results in increased phosphorylation of HCK protein
HCK protein affects the susceptibility to deoxynivalenol
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased activity of HCK protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of HCK protein; HCK protein affects the reaction [deoxynivalenol results in increased activity of CASP3 protein]; HCK protein affects the reaction [deoxynivalenol results in increased expression of TNF protein]

PMID:15772366 PMID:20181660 PMID:22491426

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

G

histone deacetylase 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of HDAC1 protein

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

G

histone deacetylase 2

affects phosphorylation

deoxynivalenol affects the phosphorylation of HDAC2 protein

NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609

G

heparin binding growth factor

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of HDGF protein

NCBI chr 2:173,370,147...173,379,756
Ensembl chr 2:173,370,465...173,379,747

G

hemogen

affects phosphorylation

deoxynivalenol affects the phosphorylation of HEMGN protein

NCBI chr 5:60,679,633...60,698,597
Ensembl chr 5:60,679,633...60,698,669

G

hypoxia inducible factor 1 subunit alpha

increases expression
multiple interactions

deoxynivalenol results in increased expression of HIF1A mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of HIF1A mRNA]

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

histone H4 transcription factor

increases expression

deoxynivalenol results in increased expression of HINFP protein

NCBI chr 8:44,634,333...44,644,288
Ensembl chr 8:44,634,333...44,641,000

G

histidine triad nucleotide binding protein 1

decreases expression

deoxynivalenol results in decreased expression of HINT1 mRNA

NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568

G

histone cluster 1 H2B family member D

increases expression

deoxynivalenol results in increased expression of H2BC5 mRNA

NCBI chr17:42,792,887...42,793,268

G

H2.0-like homeobox

increases expression

deoxynivalenol results in increased expression of HLX mRNA

NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

deoxynivalenol results in decreased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

heme oxygenase 1

decreases expression
multiple interactions
increases expression
decreases response to substance

deoxynivalenol results in decreased expression of HMOX1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of HMOX1 mRNA]
Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of HMOX1 mRNA]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]
HMOX1 protein results in decreased susceptibility to deoxynivalenol
deoxynivalenol results in increased expression of HMOX1 mRNA; deoxynivalenol results in increased expression of HMOX1 protein

PMID:24355168 PMID:26763390 PMID:31034930 PMID:31863870 PMID:34400200 More...

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

hepatocyte nuclear factor 4, alpha

increases expression
multiple interactions

deoxynivalenol results in increased expression of HNF4 mRNA; deoxynivalenol results in increased expression of HNF4A mRNA
[deoxynivalenol co-treated with Zearalenone] affects the expression of HNF4A mRNA

PMID:28865950 PMID:35314294

NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320

G

homeobox A7

increases expression
multiple interactions

deoxynivalenol results in increased expression of HOXA7 mRNA
AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of HOXA7 mRNA]

NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

increases expression

deoxynivalenol results in increased expression of HSD3B2 mRNA

NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852

G

heat shock protein 90 alpha family class B member 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of HSP90AB1 protein

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

G

heat shock protein family A (Hsp70) member 1 like

decreases expression

deoxynivalenol results in decreased expression of HSPA1L protein

NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571

G

heat shock protein family A (Hsp70) member 5

multiple interactions
increases phosphorylation
decreases expression

calpain inhibitor III inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein]; deoxynivalenol results in increased degradation of and results in decreased expression of HSPA5 protein; phenylalanyl-glycyl-NHO-Bz inhibits the reaction [deoxynivalenol results in increased degradation of HSPA5 protein]
deoxynivalenol results in increased phosphorylation of HSPA5 protein
deoxynivalenol results in decreased expression of HSPA5 mRNA

PMID:10652249 PMID:19336499 PMID:20682335 PMID:23811945 PMID:24356939

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 8

increases phosphorylation

deoxynivalenol results in increased phosphorylation of HSPA8 protein

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

heat shock protein family H (Hsp110) member 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of HSPH1 protein

NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224

G

HYLS1, centriolar and ciliogenesis associated

increases expression

deoxynivalenol results in increased expression of HYLS1 mRNA

NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760

G

intercellular adhesion molecule 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of ICAM1 mRNA; deoxynivalenol results in increased expression of ICAM1 protein
deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]

PMID:19549553 PMID:21074547 PMID:34400200

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 1

decreases expression

deoxynivalenol results in decreased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

interferon induced transmembrane protein 3

decreases expression

deoxynivalenol results in decreased expression of IFITM3 protein

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

interferon, alpha 1

decreases expression

deoxynivalenol results in decreased expression of IFNA1 mRNA

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

G

interferon alpha and beta receptor subunit 1

decreases expression

deoxynivalenol results in decreased expression of IFNAR1 mRNA

NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979

G

interferon beta 1

multiple interactions
increases expression

deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IFNB1 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]
deoxynivalenol results in increased expression of IFNB1 mRNA

PMID:14644621 PMID:17090620 PMID:19857559

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

affects expression
multiple interactions
increases expression

deoxynivalenol affects the expression of IFNG mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of CD14 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]; deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of IFNGR1 protein]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]
deoxynivalenol results in increased expression of IFNG mRNA; deoxynivalenol results in increased expression of IFNG protein
[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IFNG protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IFNG protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IFNG mRNA]

PMID:9194413 PMID:9707511 PMID:14644621 PMID:17090620 PMID:17166736 More...

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon gamma receptor 1

multiple interactions
decreases expression

deoxynivalenol inhibits the reaction [IFNG protein results in increased expression of IFNGR1 protein]
deoxynivalenol results in decreased expression of IFNGR1 mRNA

PMID:17090620 PMID:19549553

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

G

insulin-like growth factor 1

multiple interactions
increases expression
decreases expression

deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGF1 mRNA]
deoxynivalenol results in increased expression of IGF1 mRNA
deoxynivalenol results in decreased expression of IGF1 protein

PMID:19805407 PMID:32738333

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein, acid labile subunit

decreases expression
increases expression
multiple interactions

deoxynivalenol results in decreased expression of IGFALS mRNA; deoxynivalenol results in decreased expression of IGFALS protein
deoxynivalenol results in increased expression of IGFALS mRNA
deoxynivalenol inhibits the reaction [Glutathione results in increased expression of IGFALS mRNA]

PMID:19625342 PMID:19805407 PMID:23298694 PMID:32738333

NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677

G

insulin-like growth factor binding protein 3

multiple interactions

deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGFBP3 mRNA]

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

insulin-like growth factor binding protein 6

decreases expression

deoxynivalenol results in decreased expression of IGFBP6 mRNA

NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966

G

interleukin 10

increases expression

deoxynivalenol results in increased expression of IL10 mRNA

PMID:9194413 PMID:9707511 PMID:22968694

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 10 receptor subunit beta

increases expression

deoxynivalenol results in increased expression of IL10RB mRNA

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

G

interleukin 11

increases expression
affects expression
multiple interactions

deoxynivalenol results in increased expression of IL11 mRNA
deoxynivalenol affects the expression of IL11 mRNA
deoxynivalenol results in increased expression of IL11 mRNA; deoxynivalenol results in increased expression of IL11 protein
GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL11 protein]
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL11 mRNA]

PMID:15371230 PMID:15681167 PMID:32738333 PMID:34673182

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 12A

increases expression

deoxynivalenol results in increased expression of IL12A mRNA

PMID:9707511 PMID:27757495

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

G

interleukin 12B

increases expression
multiple interactions

deoxynivalenol results in increased expression of IL12B mRNA
[Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL12B protein

PMID:9194413 PMID:9707511 PMID:28935500

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

G

interleukin 13

multiple interactions

deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL13 protein]

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 15

increases expression

deoxynivalenol results in increased expression of IL15 mRNA

NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820

G

interleukin 17A

multiple interactions
increases expression

[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL17A protein; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL17A protein]

PMID:28935500 PMID:32416088

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 18

decreases expression
increases secretion
increases expression
multiple interactions

deoxynivalenol results in decreased expression of IL18 mRNA
deoxynivalenol results in increased secretion of IL18 protein
deoxynivalenol results in increased expression of IL18 mRNA; deoxynivalenol results in increased expression of IL18 protein
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL18 protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased secretion of IL18 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL18 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL18 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased secretion of IL18 protein]

PMID:22968694 PMID:35925383 PMID:36309173

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 18 receptor accessory protein

decreases expression

deoxynivalenol results in decreased expression of IL18RAP mRNA

NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959

G

interleukin 1 alpha

increases expression
multiple interactions

deoxynivalenol results in increased expression of IL1A mRNA
Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL1A mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1A mRNA]

PMID:15371230 PMID:15681167 PMID:16009389 PMID:32738333

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

increases expression
increases secretion
multiple interactions
decreases expression

deoxynivalenol results in increased expression of IL1B mRNA; deoxynivalenol results in increased expression of IL1B protein
deoxynivalenol results in increased secretion of IL1B protein
GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; [GSDME protein co-treated with deoxynivalenol] results in increased secretion of IL1B protein; [Zearalenone co-treated with deoxynivalenol] results in increased expression of IL1B mRNA; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL1B protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL1B protein]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]]; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL1B protein; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL1B protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL1B protein]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased secretion of IL1B protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased secretion of IL1B protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL1B protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL1B protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of IL1B mRNA]
deoxynivalenol results in decreased expression of IL1B mRNA

PMID:9194413 PMID:9707511 PMID:10344227 PMID:12604842 PMID:12773775 More...

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 family member 10

increases expression

deoxynivalenol results in increased expression of IL1F10 mRNA

NCBI chr 3:7,072,511...7,075,439
Ensembl chr 3:7,072,511...7,075,439

G

interleukin 1 receptor type 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of IL1R1 mRNA
IL1R1 protein affects the susceptibility to [Lipopolysaccharides co-treated with deoxynivalenol]

PMID:12773775 PMID:22968694

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 1 receptor-like 1

increases expression

deoxynivalenol results in increased expression of IL1RL1 mRNA

NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256

G

interleukin 1 receptor antagonist

increases expression

deoxynivalenol results in increased expression of IL1RN mRNA

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

G

interleukin 2

affects secretion
increases expression
increases stability
multiple interactions
affects expression

deoxynivalenol affects the secretion of IL2 protein
deoxynivalenol results in increased expression of IL2 mRNA
deoxynivalenol results in increased stability of IL2 mRNA
deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]
deoxynivalenol affects the expression of IL2 mRNA

PMID:8560498 PMID:8658534 PMID:9194413 PMID:9439728 PMID:9707511 More...

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 22 receptor subunit alpha 2

increases expression

deoxynivalenol results in increased expression of IL22RA2 mRNA

NCBI chr 1:14,353,736...14,377,844
Ensembl chr 1:14,364,489...14,377,844

G

interleukin 23 subunit alpha

increases expression

deoxynivalenol results in increased expression of IL23A mRNA

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

G

interleukin 33

increases expression
multiple interactions

deoxynivalenol results in increased expression of IL33 mRNA; deoxynivalenol results in increased expression of IL33 protein
deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL33 protein]; Oligosaccharides analog inhibits the reaction [deoxynivalenol results in increased expression of IL33 mRNA]; Oligosaccharides analog inhibits the reaction [deoxynivalenol results in increased expression of IL33 protein]

PMID:26304032 PMID:33170220

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

G

interleukin 36, gamma

increases expression

deoxynivalenol results in increased expression of IL36G protein

NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480

G

interleukin 4

increases expression
multiple interactions
affects secretion

deoxynivalenol results in increased expression of IL4 mRNA
deoxynivalenol results in increased expression of IL4 mRNA; deoxynivalenol results in increased expression of IL4 protein
deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL4 protein]
deoxynivalenol affects the secretion of IL4 protein

PMID:8560498 PMID:8658534 PMID:9194413 PMID:9707511 PMID:22846391 More...

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 5

affects secretion
increases expression
multiple interactions

deoxynivalenol affects the secretion of IL5 protein
deoxynivalenol results in increased expression of IL5 mRNA
deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]; deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL5 protein]

PMID:8560498 PMID:8658534 PMID:33170220

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

decreases expression
increases secretion
multiple interactions
increases expression
increases stability

deoxynivalenol results in decreased expression of IL6 mRNA
deoxynivalenol results in increased secretion of IL6 protein
[Zearalenone co-treated with deoxynivalenol] results in increased expression of IL6 mRNA; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; GSDME protein promotes the reaction [deoxynivalenol results in increased secretion of IL6 protein]
deoxynivalenol results in increased expression of IL6 mRNA; deoxynivalenol results in increased expression of IL6 protein
GALP protein promotes the reaction [deoxynivalenol results in increased expression of IL6 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]]; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of IL6 protein; [Docosahexaenoic Acids co-treated with Eicosapentaenoic Acid] inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of IL6 protein; acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; ATF6 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased secretion of IL6 protein]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol promotes the reaction [CREB1 protein modified form binds to IL6 promoter]]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of IL6]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased expression of IL6]; Fatty Acids, Omega-3 inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Fish Oils inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Indomethacin inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Indomethacin inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Indomethacin inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of IL6 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 protein]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of IL6 mRNA]
deoxynivalenol results in increased stability of IL6 mRNA

PMID:9194413 PMID:9707511 PMID:10344227 PMID:11295263 PMID:11922776 More...

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7

decreases expression

deoxynivalenol results in decreased expression of IL7 mRNA

NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075

G

interleukin 9

multiple interactions

deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of and results in increased secretion of IL9 protein]

NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895

G

inositol polyphosphate-5-phosphatase D

affects phosphorylation

deoxynivalenol affects the phosphorylation of INPP5D protein

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

G

interleukin-1 receptor-associated kinase 1

multiple interactions

deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of IRAK1 protein]

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

G

interferon regulatory factor 2 binding protein 2

increases expression

deoxynivalenol results in increased expression of IRF2BP2 mRNA

NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642

G

IST1 factor associated with ESCRT-III

increases expression

deoxynivalenol results in increased expression of IST1 mRNA

NCBI chr19:37,648,840...37,671,019
Ensembl chr19:37,648,095...37,670,956

G

integrin subunit alpha 10

decreases expression

deoxynivalenol results in decreased expression of ITGA10 mRNA

NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172

G

integrin subunit beta 2

increases expression

deoxynivalenol results in increased expression of ITGB2 mRNA

NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600

G

integrin subunit beta like 1

decreases expression

deoxynivalenol results in decreased expression of ITGBL1 mRNA

NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733

G

inter-alpha-trypsin inhibitor heavy chain 5

decreases expression

deoxynivalenol results in decreased expression of ITIH5 mRNA

NCBI chr17:68,248,115...68,352,216
Ensembl chr17:68,252,128...68,352,207

G

Janus kinase 1

increases expression
increases phosphorylation

deoxynivalenol results in increased expression of JAK1 mRNA
deoxynivalenol results in increased phosphorylation of JAK1 protein

PMID:22454431 PMID:36602574

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

G

Janus kinase 2

increases expression
multiple interactions

deoxynivalenol results in increased expression of JAK2 mRNA
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA]

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases phosphorylation
increases activity
increases expression
affects localization
affects activity

[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUN mRNA; deoxynivalenol results in increased expression of and results in increased phosphorylation of JUN protein
deoxynivalenol results in increased phosphorylation of JUN protein
deoxynivalenol results in increased activity of JUN protein
deoxynivalenol results in increased expression of JUN mRNA; deoxynivalenol results in increased expression of JUN protein
deoxynivalenol affects the localization of JUN protein
deoxynivalenol affects the activity of JUN protein
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUN protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of JUN protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of JUN protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of JUN protein]

PMID:10662601 PMID:12604842 PMID:15371230 PMID:15681167 PMID:15772366 More...

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression
increases activity
affects activity

4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUNB protein]
deoxynivalenol results in increased expression of JUNB mRNA
[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUNB mRNA
deoxynivalenol affects the activity of JUNB protein

PMID:10662601 PMID:15371230 PMID:15681167 PMID:15772366 PMID:33309878

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

JunD proto-oncogene, AP-1 transcription factor subunit

affects activity
multiple interactions
affects localization
increases activity
increases expression

deoxynivalenol affects the activity of JUND protein
[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUND mRNA
deoxynivalenol affects the localization of JUND protein
deoxynivalenol results in increased activity of JUND protein
deoxynivalenol results in increased expression of JUND mRNA; deoxynivalenol results in increased expression of JUND protein
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUND protein]

PMID:10662601 PMID:12604842 PMID:15772366 PMID:22846391 PMID:33309878 More...

NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799

G

lysine acetyltransferase 2A

multiple interactions

KAT2A protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]

NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166

G

lysine acetyltransferase 2B

increases expression
multiple interactions

deoxynivalenol results in increased expression of KAT2B protein
KAT2B protein affects the reaction [deoxynivalenol results in increased expression of ATF3 protein alternative form]

NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064

G

kelch repeat and BTB domain containing 11

affects phosphorylation

deoxynivalenol affects the phosphorylation of KBTBD11 protein

NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736

G

potassium calcium-activated channel subfamily M regulatory beta subunit 4

decreases expression

deoxynivalenol results in decreased expression of KCNMB4 mRNA

NCBI chr 7:52,066,145...52,119,098
Ensembl chr 7:52,066,136...52,119,278

G

KDEL endoplasmic reticulum protein retention receptor 3

decreases expression

deoxynivalenol results in decreased expression of KDELR3 mRNA

NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600

G

lysine demethylase 4B

affects phosphorylation

deoxynivalenol affects the phosphorylation of KDM4B protein

NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543

G

Kelch-like ECH-associated protein 1

decreases expression

deoxynivalenol results in decreased expression of KEAP1 mRNA

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

KH domain containing 4, pre-mRNA splicing factor

increases expression

deoxynivalenol results in increased expression of KHDC4 mRNA

NCBI chr 2:174,149,059...174,177,816
Ensembl chr 2:174,149,141...174,177,504

G

KH RNA binding domain containing, signal transduction associated 3

increases expression

deoxynivalenol results in increased expression of KHDRBS3 mRNA

NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460

G

kinesin family member 11

increases expression

deoxynivalenol results in increased expression of KIF11 mRNA

NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766

G

kinesin family member 2C

increases expression

deoxynivalenol results in increased expression of KIF2C mRNA

NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637

G

KIT ligand

increases expression

deoxynivalenol results in increased expression of KITLG mRNA

PMID:27757495 PMID:31863870

NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214

G

KLF transcription factor 4

affects localization
affects expression

deoxynivalenol affects the localization of KLF4 protein
deoxynivalenol affects the expression of KLF4 protein

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

kelch-like family member 30

decreases expression

deoxynivalenol results in decreased expression of KLHL30 mRNA

NCBI chr 9:91,942,475...91,952,756
Ensembl chr 9:91,942,504...91,952,730

G

lysine methyltransferase 2A

multiple interactions
increases expression

AG 1879 inhibits the reaction [deoxynivalenol results in increased expression of KMT2A mRNA]; deoxynivalenol promotes the reaction [SP1 protein binds to KMT2A promoter]; SP1 protein promotes the reaction [deoxynivalenol results in increased expression of KMT2A mRNA]

NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181

G

keratin 18

increases expression

deoxynivalenol results in increased expression of KRT18 protein

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166

G

keratin 20

multiple interactions
decreases expression

lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of KRT20 protein]

NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107

G

laminin subunit beta 1

decreases expression

deoxynivalenol results in decreased expression of LAMB1 mRNA

NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585

G

La ribonucleoprotein 7, transcriptional regulator

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of LARP7 protein

NCBI chr 2:215,997,641...216,012,833
Ensembl chr 2:215,997,649...216,012,865

G

lipocalin 1

increases expression

deoxynivalenol results in increased expression of LCN1 protein

NCBI chr 3:9,532,860...9,537,859
Ensembl chr 3:9,532,915...9,536,577

G

lymphocyte cytosolic protein 1

increases phosphorylation
affects phosphorylation

deoxynivalenol results in increased phosphorylation of LCP1 protein
deoxynivalenol affects the phosphorylation of LCP1 protein

PMID:23352502 PMID:23811945

NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680

G

galectin 3 binding protein

decreases expression

deoxynivalenol results in decreased expression of LGALS3BP protein

NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256

G

leucine rich repeat containing G protein coupled receptor 5

multiple interactions
decreases expression

lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of LGR5 protein]

NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446

G

luteinizing hormone/choriogonadotropin receptor

multiple interactions

[Colforsin co-treated with deoxynivalenol] results in increased expression of LHCGR mRNA

NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521

G

DNA ligase 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of LIG1 protein

NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413

G

lipase A, lysosomal acid type

decreases expression

deoxynivalenol results in decreased expression of LIPA protein

NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633

G

lamin A/C

affects phosphorylation
decreases phosphorylation

deoxynivalenol affects the phosphorylation of LMNA protein
deoxynivalenol results in decreased phosphorylation of LMNA protein

PMID:23352502 PMID:23811945

NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423

G

lamin B1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of LMNB1 protein

NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502

G

LIM domain only 2

decreases expression

deoxynivalenol results in decreased expression of LMO2 mRNA

NCBI chr 3:90,355,234...90,377,970
Ensembl chr 3:90,365,883...90,377,953

G

lysyl oxidase-like 3

decreases expression

deoxynivalenol results in decreased expression of LOXL3 mRNA

NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466

G

leupaxin

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of LPXN protein

NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084

G

lymphocyte-specific protein 1

affects phosphorylation
decreases expression
increases phosphorylation

deoxynivalenol affects the phosphorylation of LSP1 protein
deoxynivalenol results in decreased expression of LSP1 mRNA
deoxynivalenol results in increased phosphorylation of LSP1 protein

PMID:23352502 PMID:23811945 PMID:31863870

NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416

G

lymphotoxin alpha

increases expression

deoxynivalenol results in increased expression of LTA mRNA

NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859

G

lymphotoxin beta

decreases expression

deoxynivalenol results in decreased expression of LTB mRNA

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

G

latent transforming growth factor beta binding protein 2

decreases expression

deoxynivalenol results in decreased expression of LTBP2 mRNA

NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208

G

lysozyme 2

multiple interactions
decreases expression

lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of LYZ protein]

NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106

G

MAF bZIP transcription factor F

increases expression

deoxynivalenol results in increased expression of MAFF mRNA

NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851

G

mal, T-cell differentiation protein-like

decreases expression

deoxynivalenol results in decreased expression of MALL mRNA

NCBI chr 3:114,927,897...114,950,840
Ensembl chr 3:114,927,897...114,950,785

G

microtubule-associated protein 1 light chain 3 beta

increases expression
multiple interactions

deoxynivalenol results in increased expression of MAP1LC3B mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA]]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of MAP1LC3B mRNA]

PMID:34677630 PMID:35381244

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

mitogen activated protein kinase kinase 4

increases phosphorylation
multiple interactions

deoxynivalenol results in increased phosphorylation of MAP2K4 protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K4 protein]

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

G

mitogen-activated protein kinase kinase 6

multiple interactions
increases phosphorylation

AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K6 protein]

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

G

mitogen-activated protein kinase kinase kinase 5

multiple interactions
increases phosphorylation

AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP3K5 protein]

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

G

microtubule-associated protein 4

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of MAP4 protein

NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation

4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]
[deoxynivalenol results in increased phosphorylation of MAPK1 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK1 protein; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]

PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 More...

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen-activated protein kinase 12

decreases expression

deoxynivalenol results in decreased expression of MAPK12 mRNA

NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664

G

mitogen activated protein kinase 14

multiple interactions
increases expression
increases phosphorylation

deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK14 protein
deoxynivalenol results in increased expression of MAPK14 mRNA
deoxynivalenol results in increased phosphorylation of MAPK14 protein

PMID:15976193 PMID:16364386 PMID:20702593

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

[deoxynivalenol results in increased phosphorylation of MAPK3 protein] which results in increased expression of CXCL8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK3 protein; MAPK3 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]; Lipopolysaccharides inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]

PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 More...

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

decreases activity
increases phosphorylation
multiple interactions

deoxynivalenol results in decreased activity of MAPK8 protein
deoxynivalenol results in increased phosphorylation of MAPK8 protein
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein]
[deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK8 protein

PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15570035 More...

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 9

decreases activity
increases phosphorylation
decreases phosphorylation
decreases expression
multiple interactions

deoxynivalenol results in decreased activity of MAPK9 protein
deoxynivalenol results in increased phosphorylation of MAPK9 protein
deoxynivalenol results in decreased phosphorylation of MAPK9 protein
deoxynivalenol results in decreased expression of MAPK9 mRNA
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; AG 1879 inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; Eicosapentaenoic Acid inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]; Fish Oils inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK9 protein]
[deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK9 protein; deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK9 protein

PMID:12377986 PMID:12604842 PMID:14644621 PMID:14690764 PMID:15371230 More...

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

myristoylated alanine rich protein kinase C substrate

increases phosphorylation

deoxynivalenol results in increased phosphorylation of MARCKS protein

NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012

G

MDM2 proto-oncogene

increases expression

deoxynivalenol results in increased expression of MDM2 mRNA

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

MDM4 regulator of p53

increases expression

deoxynivalenol results in increased expression of MDM4 mRNA

NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226

G

Meis homeobox 3

decreases response to substance
decreases expression

MEIS3 protein results in decreased susceptibility to deoxynivalenol
deoxynivalenol results in decreased expression of MEIS3 mRNA

NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691

G

MET proto-oncogene, receptor tyrosine kinase

affects phosphorylation

deoxynivalenol affects the phosphorylation of MET protein

NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876

G

methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit

increases expression

deoxynivalenol results in increased expression of METTL14 mRNA

NCBI chr 2:211,530,598...211,546,845
Ensembl chr 2:211,530,602...211,546,821

G

MICAL-like 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of MICALL1 protein

NCBI chr 7:110,676,706...110,707,171
Ensembl chr 7:110,676,775...110,707,177

G

microRNA 221

multiple interactions

[Zearalenone co-treated with deoxynivalenol] results in decreased expression of MIR221 mRNA

NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573

G

marker of proliferation Ki-67

increases phosphorylation
multiple interactions
increases expression

deoxynivalenol results in increased phosphorylation of MKI67 protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of MKI67 protein]
deoxynivalenol results in increased expression of MKI67 mRNA

PMID:23352502 PMID:23811945 PMID:31863870 PMID:32416088

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

MAPK interacting serine/threonine kinase 2

affects phosphorylation
decreases expression

deoxynivalenol affects the phosphorylation of MKNK2 protein
deoxynivalenol results in decreased expression of MKNK2 mRNA

PMID:23811945 PMID:31863870

NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827

G

methylmalonyl-CoA mutase

decreases expression

deoxynivalenol results in decreased expression of MMUT protein

NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046

G

myeloperoxidase

increases activity

deoxynivalenol results in increased activity of MPO protein

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

melanocortin 2 receptor accessory protein 2

decreases expression

deoxynivalenol results in decreased expression of MRAP2 mRNA

NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886

G

mitochondrial ribosomal protein L39

increases expression

deoxynivalenol results in increased expression of MRPL39 mRNA

NCBI chr11:23,779,655...23,795,146
Ensembl chr11:23,779,662...23,795,125

G

mitochondrial ribosomal protein S18B

increases expression

deoxynivalenol results in increased expression of MRPS18B mRNA

NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260

G

mitochondrial ribosomal protein S22

increases expression

deoxynivalenol results in increased expression of MRPS22 mRNA

NCBI chr 8:99,184,110...99,197,278
Ensembl chr 8:99,184,109...99,197,291

G

mitochondrial ribosomal protein S30

increases expression

deoxynivalenol results in increased expression of MRPS30 mRNA

PMID:24247028 PMID:31863870

NCBI chr 2:50,456,253...50,463,128
Ensembl chr 2:50,456,255...50,463,105

G

mitochondrial ribosomal protein S31

increases expression

deoxynivalenol results in increased expression of MRPS31 mRNA

NCBI chr16:69,601,349...69,621,609
Ensembl chr16:69,601,349...69,630,654

G

msh homeobox 2

increases expression

deoxynivalenol results in increased expression of MSX2 mRNA

NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879

G

metastasis associated 1 family, member 3

affects phosphorylation

deoxynivalenol affects the phosphorylation of MTA3 protein

NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883

G

metadherin

affects phosphorylation

deoxynivalenol affects the phosphorylation of LYRIC protein

NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

decreases expression

deoxynivalenol results in decreased expression of MTHFD2 mRNA

NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608

G

mechanistic target of rapamycin kinase

multiple interactions
decreases phosphorylation

lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of MTOR protein]

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

Mtr4 exosome RNA helicase

increases expression

deoxynivalenol results in increased expression of MTREX mRNA

NCBI chr 2:44,500,326...44,560,624
Ensembl chr 2:44,461,444...44,560,627

G

mucin 16, cell surface associated

affects phosphorylation

deoxynivalenol affects the phosphorylation of MUC16 protein

NCBI chr 8:16,164,531...16,323,126

G

mucin 2, oligomeric mucus/gel-forming

multiple interactions
decreases expression

lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of MUC2 protein]

NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756

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mucin 5AC, oligomeric mucus/gel-forming

increases expression
multiple interactions

deoxynivalenol results in increased expression of MUC5AC mRNA
deoxynivalenol results in increased expression of and results in increased secretion of MUC5AC protein

NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475

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mucin 5B, oligomeric mucus/gel-forming

increases expression
multiple interactions

deoxynivalenol results in increased expression of MUC5B mRNA
deoxynivalenol results in increased expression of and results in increased secretion of MUC5B protein

NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250

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MYB binding protein 1a

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of MYBBP1A protein

NCBI chr10:57,056,897...57,067,258
Ensembl chr10:57,056,874...57,067,255

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MYC proto-oncogene, bHLH transcription factor

increases expression

deoxynivalenol results in increased expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

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MYCN proto-oncogene, bHLH transcription factor

affects phosphorylation

deoxynivalenol affects the phosphorylation of MYCN protein

NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590

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MYD88, innate immune signal transduction adaptor

multiple interactions
increases expression

deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of MYD88 protein]
deoxynivalenol results in increased expression of MYD88 mRNA; deoxynivalenol results in increased expression of MYD88 protein

PMID:26961612 PMID:34400200

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

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myosin heavy chain 11

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of MYH11 protein

NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459

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myosin, heavy chain 9

affects phosphorylation
increases phosphorylation

deoxynivalenol affects the phosphorylation of MYH9 protein
deoxynivalenol results in increased phosphorylation of MYH9 protein

PMID:23352502 PMID:23811945

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

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myosin light chain 9

multiple interactions
increases expression

Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYL9 protein modified form]

NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333

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myosin light chain kinase

increases expression
multiple interactions

deoxynivalenol results in increased expression of MYLK mRNA; deoxynivalenol results in increased expression of MYLK protein
Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of MYLK protein]

NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261

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myosin VC

decreases expression

deoxynivalenol results in decreased expression of MYO5C mRNA

NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483

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myeloid zinc finger 1

decreases expression

deoxynivalenol results in decreased expression of MZF1 protein

NCBI chr 1:73,670,522...73,682,885
Ensembl chr 1:73,670,541...73,681,635

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N-acetyl-alpha-glucosaminidase

decreases expression

deoxynivalenol results in decreased expression of NAGLU mRNA

NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972

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nicotinamide phosphoribosyltransferase

increases expression

deoxynivalenol results in increased expression of NAMPT mRNA

NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100

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nanos C2HC-type zinc finger 1

decreases expression

deoxynivalenol results in decreased expression of NANOS1 mRNA

NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730

G

nucleolin

affects phosphorylation

deoxynivalenol affects the phosphorylation of NCL protein

NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136

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NDC80 kinetochore complex component

increases expression

deoxynivalenol results in increased expression of NDC80 mRNA

NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924

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NADH:ubiquinone oxidoreductase subunit B7

decreases expression

deoxynivalenol results in decreased expression of NDUFB7 protein

NCBI chr19:24,568,241...24,572,579
Ensembl chr19:24,568,241...24,572,579

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NADH:ubiquinone oxidoreductase subunit B8

decreases expression

deoxynivalenol results in decreased expression of NDUFB8 protein

NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817

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NADH:ubiquinone oxidoreductase subunit B9

decreases expression

deoxynivalenol results in decreased expression of NDUFB9 protein

NCBI chr 7:90,480,948...90,487,367
Ensembl chr 7:90,436,621...90,488,009

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NADH:ubiquinone oxidoreductase subunit S4

decreases expression

deoxynivalenol results in decreased expression of NDUFS4 protein

NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846

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NADH:ubiquinone oxidoreductase subunit S5

decreases expression

deoxynivalenol results in decreased expression of NDUFS5 protein

NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
Ensembl chr14:135,974,034...135,979,603
Ensembl chr 2:135,974,034...135,979,603

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NADH:ubiquinone oxidoreductase core subunit S7

decreases expression

deoxynivalenol results in decreased expression of NDUFS7 protein

NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195

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NADH:ubiquinone oxidoreductase subunit V3

decreases expression

deoxynivalenol results in decreased expression of NDUFV3 protein

NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074

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NEDD4 like E3 ubiquitin protein ligase

increases expression

deoxynivalenol results in increased expression of NEDD4L mRNA

NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137

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nuclear factor of activated T-cells 1

affects localization

deoxynivalenol affects the localization of NFATC1 protein

PMID:21074547 PMID:22846391

NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028

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NFE2 like bZIP transcription factor 2

increases activity
decreases expression
multiple interactions
increases expression

deoxynivalenol analog results in increased activity of NFE2L2 protein; deoxynivalenol results in increased activity of NFE2L2 protein
deoxynivalenol results in decreased expression of NFE2L2 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of NFE2L2 mRNA]; Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of NFE2L2 protein]

PMID:30244016 PMID:34400200 PMID:34677630 PMID:37419272

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

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nuclear factor kappa B subunit 1

multiple interactions
increases expression
increases activity
affects localization

4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of NFKB1 protein]; deoxynivalenol results in decreased activity of [NFKB1 protein binds to NFKB1 protein]; deoxynivalenol results in decreased activity of [REL protein binds to NFKB1 protein]
deoxynivalenol results in increased expression of NFKB1 mRNA
deoxynivalenol affects the localization of NFKB1 protein

PMID:8887449 PMID:12604842 PMID:15772366 PMID:35314294

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

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nuclear factor kappa B subunit 2

increases expression
multiple interactions

deoxynivalenol results in increased expression of NFKB2 mRNA
deoxynivalenol inhibits the reaction [NFKB2 protein binds to CXCL8 promoter]

PMID:17636245 PMID:22846391

NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213

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NFKB inhibitor alpha

increases degradation
multiple interactions
increases phosphorylation
increases expression
decreases expression

deoxynivalenol results in increased degradation of NFKBIA protein
deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of NFKBIA protein]
deoxynivalenol results in increased phosphorylation of NFKBIA protein
deoxynivalenol results in increased expression of NFKBIA mRNA
deoxynivalenol results in decreased expression of NFKBIA mRNA; deoxynivalenol results in decreased expression of NFKBIA protein
lipopolysaccharide, E coli O55-B5 inhibits the reaction [deoxynivalenol results in increased degradation of NFKBIA protein]

PMID:8887449 PMID:18485432 PMID:23253260 PMID:24937323 PMID:26961612 More...

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

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NFKB inhibitor beta

increases expression

deoxynivalenol results in increased expression of NFKBIB mRNA

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

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nuclear transcription factor Y subunit alpha

increases expression

deoxynivalenol results in increased expression of NFYA protein

NCBI chr 9:12,587,437...12,613,911
Ensembl chr 9:12,586,259...12,613,898

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NHERF family PDZ scaffold protein 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of NHERF1 protein

NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598

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niban apoptosis regulator 3

affects phosphorylation

deoxynivalenol affects the phosphorylation of NIBAN3 protein

NCBI chr16:18,307,122...18,318,589
Ensembl chr16:18,307,221...18,318,585

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NIPBL, cohesin loading factor

increases phosphorylation

deoxynivalenol results in increased phosphorylation of NIPBL protein

NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899

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NLR family, pyrin domain containing 3

multiple interactions
increases expression

deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 mRNA]; deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of NLRP3 protein]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of NLRP3 mRNA]; fumonisin B1 promotes the reaction [deoxynivalenol results in increased expression of NLRP3 protein]
deoxynivalenol results in increased expression of NLRP3 mRNA; deoxynivalenol results in increased expression of NLRP3 protein

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

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nucleotide-binding oligomerization domain containing 2

multiple interactions

[[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which affects the localization of ELAVL1 protein] which co-treated with deoxynivalenol] promotes the reaction [[ELAVL1 protein binds to ATF3 3' UTR] which results in increased stability of ATF3 mRNA]; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the localization of ELAVL1 protein; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of ATF3 mRNA; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA; [[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of ATF3 mRNA]; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL1 mRNA]; [Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL1 mRNA]; ELAVL1 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] results in increased stability of CXCL8 mRNA]

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

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nucleolar and coiled-body phosphoprotein 1

increases expression

deoxynivalenol results in increased expression of NOLC1 mRNA

NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088

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NOP56 ribonucleoprotein

affects phosphorylation
increases phosphorylation

deoxynivalenol affects the phosphorylation of NOP56 protein
deoxynivalenol results in increased phosphorylation of NOP56 protein

PMID:23352502 PMID:23811945

NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841

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nitric oxide synthase 2

multiple interactions
increases activity
increases expression

Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; deoxynivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein]
deoxynivalenol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
deoxynivalenol results in increased activity of NOS2 protein
deoxynivalenol results in increased expression of NOS2 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; deoxynivalenol results in increased ubiquitination of and results in increased degradation of NOS2 protein; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [deoxynivalenol results in increased degradation of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]

PMID:19857559 PMID:21748807 PMID:24937323 PMID:25766886 PMID:32416088 More...

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

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neuropeptide FF receptor 2

increases expression

deoxynivalenol results in increased expression of NPFFR2 mRNA

NCBI chr14:18,513,120...18,558,074
Ensembl chr14:18,513,277...18,521,919

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nucleophosmin 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of NPM1 protein

NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645

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neuropeptide Y

increases expression

deoxynivalenol results in increased expression of NPY mRNA

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

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NAD(P)H quinone dehydrogenase 1

increases expression
decreases expression
multiple interactions

deoxynivalenol results in increased expression of NQO1 mRNA
deoxynivalenol results in decreased expression of NQO1 mRNA
Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of NQO1 protein]

PMID:34400200 PMID:37419272

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

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nuclear receptor subfamily 1, group D, member 1

increases expression
multiple interactions
decreases expression

deoxynivalenol results in increased expression of NR1D1 mRNA
BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of NR1D1 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D1 mRNA]

PMID:22846391 PMID:36602574

NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705

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nuclear receptor subfamily 1, group D, member 2

multiple interactions

deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of NR1D2 mRNA]

NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553

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nuclear receptor subfamily 4, group A, member 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of NR4A1 mRNA
[Colforsin co-treated with deoxynivalenol] results in increased expression of NR4A1 mRNA

PMID:15371230 PMID:26783879

NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297

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nuclear receptor subfamily 4, group A, member 3

increases expression

deoxynivalenol results in increased expression of NR4A3 mRNA

NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733

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nuclear receptor subfamily 5, group A, member 1

decreases expression

deoxynivalenol results in decreased expression of NR5A1 mRNA

NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328

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negative regulator of reactive oxygen species

affects phosphorylation

deoxynivalenol affects the phosphorylation of NRROS protein

NCBI chr11:68,628,641...68,646,152
Ensembl chr11:68,628,712...68,646,142

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neurotrophic receptor tyrosine kinase 2

decreases expression

deoxynivalenol results in decreased expression of NTRK2 mRNA

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

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nuclear casein kinase and cyclin-dependent kinase substrate 1

decreases phosphorylation
affects phosphorylation

deoxynivalenol results in decreased phosphorylation of NUCKS1 protein
deoxynivalenol affects the phosphorylation of NUCKS1 protein

PMID:23352502 PMID:23811945

NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229

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NudC domain containing 1

increases expression

deoxynivalenol results in increased expression of NUDCD1 mRNA

NCBI chr 7:75,550,650...75,595,976
Ensembl chr 7:75,550,346...75,595,900

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nuclear FMR1 interacting protein 1

increases expression

deoxynivalenol results in increased expression of NUFIP1 mRNA

NCBI chr15:51,429,518...51,460,308
Ensembl chr15:51,429,549...51,460,310

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nuclear mitotic apparatus protein 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of NUMA1 protein

NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855

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nucleoporin 155

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of NUP155 protein

NCBI chr 2:57,201,310...57,252,918
Ensembl chr 2:57,201,272...57,254,148

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nucleoporin 98 and 96 precursor

affects phosphorylation
increases phosphorylation

deoxynivalenol affects the phosphorylation of NUP98 protein
deoxynivalenol results in increased phosphorylation of NUP98 protein

NCBI chr 1:156,494,423...156,591,415
Ensembl chr 1:156,494,423...156,591,415

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nucleolar and spindle associated protein 1

increases expression

deoxynivalenol results in increased expression of NUSAP1 mRNA

NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624

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2'-5' oligoadenylate synthetase 2

decreases expression

deoxynivalenol results in decreased expression of OAS2 mRNA

NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371

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occludin

affects localization
decreases expression
multiple interactions
increases expression

deoxynivalenol affects the localization of OCLN protein
deoxynivalenol results in decreased expression of OCLN mRNA; deoxynivalenol results in decreased expression of OCLN protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of OCLN protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of OCLN mRNA]
deoxynivalenol results in increased expression of OCLN mRNA

PMID:20362602 PMID:24568843 PMID:34506767 PMID:35381244 PMID:35817260

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

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ornithine decarboxylase 1

increases activity

deoxynivalenol results in increased activity of ODC1 protein

NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440

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O-GlcNAcase

increases expression

deoxynivalenol results in increased expression of OGA mRNA

NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359

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8-oxoguanine DNA glycosylase

increases expression

deoxynivalenol results in increased expression of OGG1 mRNA; deoxynivalenol results in increased expression of OGG1 protein

NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766

G

Opa interacting protein 5

increases expression

deoxynivalenol results in increased expression of OIP5 mRNA

NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250

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oxidative stress responsive serine-rich 1

increases expression

deoxynivalenol results in increased expression of OSER1 mRNA

NCBI chr 3:152,066,975...152,085,180
Ensembl chr 3:152,066,975...152,085,149

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osteoclast stimulating factor 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of OSTF1 protein

NCBI chr 1:216,002,037...216,049,226
Ensembl chr 1:216,002,044...216,049,221

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prolyl 4-hydroxylase subunit alpha 3

decreases expression

deoxynivalenol results in decreased expression of P4HA3 mRNA

NCBI chr 1:154,628,723...154,663,779
Ensembl chr 1:154,628,736...154,663,775

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palladin, cytoskeletal associated protein

affects phosphorylation

deoxynivalenol affects the phosphorylation of PALLD protein

NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337

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poly (ADP-ribose) polymerase 1

increases cleavage
multiple interactions
increases expression

deoxynivalenol results in increased cleavage of PARP1 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone affects the reaction [deoxynivalenol affects the expression of and results in increased cleavage of PARP1 protein]; deoxynivalenol affects the expression of and results in increased cleavage of PARP1 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein]; deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein; GSDME protein inhibits the reaction [deoxynivalenol results in increased cleavage of PARP1 protein]
deoxynivalenol results in increased expression of PARP1 mRNA

PMID:19410639 PMID:34677630 PMID:35925383

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

decreases expression

deoxynivalenol results in decreased expression of PCK2 mRNA

NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283

G

proliferating cell nuclear antigen

multiple interactions
decreases expression

lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of PCNA protein]

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

procollagen C-endopeptidase enhancer

decreases expression

deoxynivalenol results in decreased expression of PCOLCE mRNA

NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508

G

prenylcysteine oxidase 1 like

decreases expression

deoxynivalenol results in decreased expression of PCYOX1L mRNA

NCBI chr18:55,150,637...55,161,334
Ensembl chr18:55,150,650...55,161,327

G

programmed cell death 1

increases expression

deoxynivalenol results in increased expression of PDCD1 mRNA

NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937

G

programmed cell death 11

affects phosphorylation

deoxynivalenol affects the phosphorylation of PDCD11 protein

NCBI chr 1:245,980,840...246,021,999
Ensembl chr 1:245,980,880...246,021,999

G

phosphodiesterase 12

increases expression

deoxynivalenol results in increased expression of PDE12 mRNA

NCBI chr16:1,920,062...1,925,638
Ensembl chr16:1,915,386...1,925,887

G

PDZ and LIM domain 2

affects phosphorylation
increases phosphorylation

deoxynivalenol affects the phosphorylation of PDLIM2 protein
deoxynivalenol results in increased phosphorylation of PDLIM2 protein

PMID:23352502 PMID:23811945

NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242

G

PDZ and LIM domain 4

affects phosphorylation

deoxynivalenol affects the phosphorylation of PDLIM4 protein

NCBI chr10:38,198,686...38,212,935
Ensembl chr10:38,198,689...38,212,938

G

decaprenyl diphosphate synthase subunit 2

increases expression

deoxynivalenol results in increased expression of PDSS2 mRNA

NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708

G

proliferation and apoptosis adaptor protein 15

affects phosphorylation

deoxynivalenol affects the phosphorylation of PEA15A protein

NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499

G

period circadian regulator 1

multiple interactions

deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 mRNA]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER1 protein]

NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431

G

period circadian regulator 2

multiple interactions
decreases expression

BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER2 protein]
deoxynivalenol results in decreased expression of PER2 mRNA; deoxynivalenol results in decreased expression of PER2 protein

NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459

G

period circadian regulator 3

multiple interactions
decreases expression

BMAL1 protein promotes the reaction [deoxynivalenol results in decreased expression of PER3 protein]; deoxynivalenol inhibits the reaction [BMAL1 protein results in increased expression of PER3 mRNA]

NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607

G

progesterone receptor

multiple interactions
increases expression

afimoxifene inhibits the reaction [deoxynivalenol results in increased expression of PGR mRNA]; deoxynivalenol promotes the reaction [Estradiol results in increased expression of PGR mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of PGR mRNA]; ESR1 promotes the reaction [deoxynivalenol results in increased expression of PGR mRNA]

NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344

G

progesterone receptor membrane component 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of PGRMC1 protein

NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682

G

phosphorylated adaptor for RNA export

increases expression

deoxynivalenol results in increased expression of PHAX mRNA

NCBI chr18:50,053,133...50,069,823
Ensembl chr18:50,053,023...50,069,823

G

phosphoglycerate dehydrogenase

decreases expression

deoxynivalenol results in decreased expression of PHGDH mRNA

NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944

G

pleckstrin homology-like domain, family A, member 1

increases expression

deoxynivalenol results in increased expression of PHLDA1 mRNA

NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861

G

pleckstrin homology-like domain, family A, member 3

increases expression

deoxynivalenol results in increased expression of PHLDA3 mRNA

NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335

G

phosphatidylinositol 4-kinase beta

affects phosphorylation

deoxynivalenol affects the phosphorylation of PI4KB protein

NCBI chr 2:182,540,377...182,572,684
Ensembl chr 2:182,540,567...182,588,488

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

affects phosphorylation

deoxynivalenol affects the phosphorylation of PIK3CG protein

NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043

G

plectin

affects phosphorylation
decreases phosphorylation

deoxynivalenol affects the phosphorylation of PLEC protein
deoxynivalenol results in decreased phosphorylation of PLEC protein

PMID:23352502 PMID:23811945

NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467

G

pleckstrin homology domain containing A6

affects phosphorylation

deoxynivalenol affects the phosphorylation of PLEKHA6 protein

NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673

G

pleckstrin homology domain containing O2

affects phosphorylation

deoxynivalenol affects the phosphorylation of PLEKHO2 protein

NCBI chr 8:66,079,106...66,105,283
Ensembl chr 8:66,078,448...66,105,266

G

perilipin 2

increases expression

deoxynivalenol results in increased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

phospholipid phosphatase 5

decreases expression

deoxynivalenol results in decreased expression of PLPP5 mRNA

NCBI chr16:66,349,483...66,353,887
Ensembl chr16:66,349,502...66,464,797

G

pleiotropic regulator 1

increases expression

deoxynivalenol results in increased expression of PLRG1 mRNA

NCBI chr 2:168,408,139...168,424,470
Ensembl chr 2:168,408,124...168,424,522

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression

deoxynivalenol results in increased expression of PMAIP1 mRNA

PMID:22846391 PMID:24247028

NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429

G

PML nuclear body scaffold

decreases phosphorylation
affects phosphorylation

deoxynivalenol results in decreased phosphorylation of PML protein
deoxynivalenol affects the phosphorylation of PML protein

PMID:23352502 PMID:23811945

NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971

G

podocan-like 1

decreases expression

deoxynivalenol results in decreased expression of PODNL1 mRNA

NCBI chr19:24,027,261...24,033,867
Ensembl chr19:24,027,297...24,033,846

G

peroxisome proliferator-activated receptor gamma

multiple interactions
decreases activity
increases expression

15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [deoxynivalenol results in increased expression of PPARG protein]; EGR1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; lipopolysaccharide, E coli O55-B5 affects the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; MAPK1 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; MAPK3 protein promotes the reaction [deoxynivalenol results in increased expression of PPARG mRNA]; PPARG protein affects the reaction [deoxynivalenol results in decreased degradation of CXCL8 mRNA]; U 0126 inhibits the reaction [deoxynivalenol results in increased expression of PPARG mRNA]
deoxynivalenol results in decreased activity of PPARG protein

PMID:18485432 PMID:27481073

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

increases expression

deoxynivalenol results in increased expression of PPM1D mRNA

NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607

G

protein phosphatase 2 catalytic subunit alpha

increases expression

deoxynivalenol results in increased expression of PPP2CA mRNA

NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862

G

protein phosphatase 3 catalytic subunit beta

increases expression
multiple interactions

deoxynivalenol results in increased expression of PPP3CB mRNA
Fatty Acids, Omega-3 promotes the reaction [deoxynivalenol results in increased expression of PPP3CB mRNA]

PMID:15371230 PMID:15681167

NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981

G

protein regulator of cytokinesis 1

increases expression

deoxynivalenol results in increased expression of PRC1 mRNA

NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765

G

proline and arginine rich end leucine rich repeat protein

decreases expression

deoxynivalenol results in decreased expression of PRELP mRNA

NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270

G

protein kinase cAMP-dependent type I regulatory subunit alpha

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of PRKAR1A protein

NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041

G

protein kinase cAMP-dependent type II regulatory subunit alpha

increases phosphorylation

deoxynivalenol results in increased phosphorylation of PRKAR2A protein

NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628

G

protein kinase C, alpha

multiple interactions
affects localization

Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCA protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCA protein]

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

G

protein kinase C, epsilon

affects localization
multiple interactions

deoxynivalenol affects the localization of PRKCE protein
Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCE protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCE protein]

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

G

protein kinase C, gamma

multiple interactions
affects localization

Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCG protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol affects the localization of PRKCG protein]

NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384

G

protein kinase D2

affects phosphorylation

deoxynivalenol affects the phosphorylation of PRKD2 protein

NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376

G

protein S

decreases expression

deoxynivalenol results in decreased expression of PROS1 mRNA

NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286

G

pre-mRNA processing factor 38B

increases expression

deoxynivalenol results in increased expression of PRPF38B mRNA

NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250

G

proline rich 5 like

decreases expression

deoxynivalenol results in decreased expression of PRR5L mRNA

NCBI chr 3:88,001,951...88,173,532
Ensembl chr 3:88,003,617...88,082,763

G

phosphoserine aminotransferase 1

decreases expression

deoxynivalenol results in decreased expression of PSAT1 mRNA

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

PC4 and SRSF1 interacting protein 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of PSIP1 protein

NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257

G

proteasome 20S subunit beta 8

decreases expression

deoxynivalenol results in decreased expression of PSMB8 mRNA

NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283

G

proteasome 26S subunit, non-ATPase 12

increases expression

deoxynivalenol results in increased expression of PSMD12 mRNA

NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287

G

paraspeckle component 1

increases expression

deoxynivalenol results in increased expression of PSPC1 mRNA

NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202

G

proline-serine-threonine phosphatase-interacting protein 2

increases expression

deoxynivalenol results in increased expression of PSTPIP2 mRNA

NCBI chr18:71,310,387...71,396,752
Ensembl chr18:71,311,020...71,395,709

G

phosphatase and tensin homolog

increases expression

deoxynivalenol results in increased expression of PTEN mRNA

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin E synthase

increases expression
decreases expression

deoxynivalenol results in increased expression of PTGES mRNA
deoxynivalenol results in decreased expression of PTGES mRNA

PMID:21873375 PMID:25549547

NCBI chr 3:14,177,892...14,189,236

G

prostaglandin-endoperoxide synthase 2

increases expression
increases stability
multiple interactions

deoxynivalenol results in increased expression of PTGS2 mRNA; deoxynivalenol results in increased expression of PTGS2 protein
deoxynivalenol results in increased stability of PTGS2 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; Indomethacin promotes the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased stability of PTGS2 mRNA]
Lutein inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]

PMID:11922776 PMID:12377986 PMID:12649040 PMID:14514436 PMID:15570035 More...

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine phosphatase, non-receptor type 14

increases phosphorylation

deoxynivalenol results in increased phosphorylation of PTPN14 protein

NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088

G

protein tyrosine phosphatase, non-receptor type 22

increases expression

deoxynivalenol results in increased expression of PTPN22 mRNA

NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779

G

protein tyrosine phosphatase, receptor type, J

increases expression

deoxynivalenol results in increased expression of PTPRJ mRNA

NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260

G

PYD and CARD domain containing

multiple interactions

[deoxynivalenol co-treated with fumonisin B1] results in increased expression of PYCARD mRNA; [deoxynivalenol co-treated with fumonisin B1] results in increased expression of PYCARD protein

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

G

peptide YY

increases expression
multiple interactions

deoxynivalenol results in increased expression of PYY protein; deoxynivalenol results in increased expression of PYY protein alternative form
[Ruthenium Red co-treated with N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine] inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form]; N-(2-hydroxy-3-(2-cyano-3-chlorophenoxy)propyl)-1,1-dimethyl-2-(2-nephthyl)ethylamine inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form]; Ruthenium Red inhibits the reaction [deoxynivalenol results in increased expression of PYY protein alternative form]

PMID:22903826 PMID:26979077

NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815

G

RAB18, member RAS oncogene family

increases expression

deoxynivalenol results in increased expression of RAB18 protein

NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043

G

ribonucleic acid export 1

increases expression

deoxynivalenol results in increased expression of RAE1 mRNA

NCBI chr 3:161,779,096...161,794,048
Ensembl chr 3:161,779,088...161,794,038

G

RALY heterogeneous nuclear ribonucleoprotein

increases expression

deoxynivalenol results in increased expression of RALY protein

NCBI chr 3:143,306,039...143,370,542
Ensembl chr 3:143,306,300...143,370,539

G

receptor activity modifying protein 1

decreases expression

deoxynivalenol results in decreased expression of RAMP1 mRNA

NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151

G

RAN binding protein 2

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of RANBP2 protein

NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481

G

ribonucleoprotein, PTB-binding 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RAVER1 protein

NCBI chr 8:19,610,464...19,629,188
Ensembl chr 8:19,610,466...19,629,152

G

RB binding protein 5, histone lysine methyltransferase complex subunit

increases expression

deoxynivalenol results in increased expression of RBBP5 mRNA

NCBI chr13:43,912,254...43,939,107
Ensembl chr13:43,912,254...43,939,107

G

RB binding protein 6, ubiquitin ligase

increases expression

deoxynivalenol results in increased expression of RBBP6 mRNA

NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678

G

RNA binding motif protein 12

increases expression

deoxynivalenol results in increased expression of RBM12 mRNA

NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915
Ensembl chr 3:144,611,623...144,629,915

G

RNA binding motif protein 15

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RBM15 protein

NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703

G

RNA binding motif protein 17

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RBM17 protein

NCBI chr17:66,937,140...66,954,034
Ensembl chr17:66,937,140...66,954,014

G

RNA binding motif protein 25

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RBM25 protein

PMID:23352502 PMID:23811945

NCBI chr 6:103,271,775...103,319,090
Ensembl chr 6:103,271,801...103,317,854

G

RNA binding motif protein 3

decreases expression

deoxynivalenol results in decreased expression of RBM3 mRNA

NCBI chr X:14,348,909...14,352,387
Ensembl chr X:14,348,910...14,353,580

G

RNA binding motif protein 39

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RBM39 protein

NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213

G

regulator of chromosome condensation 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RCC1 protein

NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577

G

REST corepressor 1

increases expression

deoxynivalenol results in increased expression of RCOR1 mRNA

NCBI chr 6:130,069,606...130,146,164
Ensembl chr 6:130,069,392...130,146,153

G

REL proto-oncogene, NF-kB subunit

affects localization
increases activity
multiple interactions

deoxynivalenol affects the localization of REL protein
deoxynivalenol results in increased activity of REL protein
4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of REL protein]; deoxynivalenol results in decreased activity of [REL protein binds to NFKB1 protein]

PMID:8887449 PMID:12604842 PMID:15772366

NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892

G

RELA proto-oncogene, NF-kB subunit

affects localization
increases expression
increases phosphorylation
multiple interactions
increases activity

deoxynivalenol affects the localization of RELA protein
deoxynivalenol results in increased expression of RELA mRNA; deoxynivalenol results in increased expression of RELA protein
deoxynivalenol results in increased phosphorylation of RELA protein
Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased phosphorylation of RELA protein]
[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein; ATF3 protein affects the reaction [[[Acetylmuramyl-Alanyl-Isoglutamine binds to and results in increased activity of NOD2 protein] which co-treated with deoxynivalenol] affects the phosphorylation of RELA protein]; deoxynivalenol promotes the reaction [RELA protein binds to CXCL8 promoter]; EIF2AK2 protein affects the reaction [deoxynivalenol results in increased activity of RELA protein]; Lutein inhibits the reaction [deoxynivalenol affects the localization of RELA protein]; Lutein inhibits the reaction [deoxynivalenol results in increased expression of RELA protein]; RELA protein promotes the reaction [deoxynivalenol results in increased expression of CXCL8 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased activity of RELA protein]

PMID:16424113 PMID:17636245 PMID:18599499 PMID:20347963 PMID:22003189 More...

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RELB proto-oncogene, NF-kB subunit

increases expression

deoxynivalenol results in increased expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

regulator of cell cycle

increases expression

deoxynivalenol results in increased expression of RGCC mRNA

NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141

G

regulator of G-protein signaling 4

decreases expression

deoxynivalenol results in decreased expression of RGS4 mRNA

NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068

G

regulator of G-protein signaling 5

decreases expression

deoxynivalenol results in decreased expression of RGS5 mRNA

NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518

G

ras homolog family member H

increases expression

deoxynivalenol results in increased expression of RHOH mRNA

NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369

G

RPTOR independent companion of MTOR, complex 2

increases expression

deoxynivalenol results in increased expression of RICTOR mRNA

NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426

G

receptor-interacting serine-threonine kinase 2

increases expression

deoxynivalenol results in increased expression of RIPK2 mRNA

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

G

ribonuclease T2

decreases expression

deoxynivalenol results in decreased expression of RNASET2 mRNA

NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147

G

ring finger protein 111

increases expression

deoxynivalenol results in increased expression of RNF111 mRNA

NCBI chr 8:71,103,967...71,180,172
Ensembl chr 8:71,103,973...71,145,070

G

RNA binding protein with serine rich domain 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of RNPS1 protein

NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858

G

RAR-related orphan receptor A

increases expression

deoxynivalenol results in increased expression of RORA mRNA

NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931

G

ribosomal protein L22 like 1

decreases expression

deoxynivalenol results in decreased expression of RPL22L1 mRNA

NCBI chr 2:111,754,687...111,756,623
Ensembl chr 2:111,754,687...111,756,625

G

ribosomal protein L27A

decreases expression

deoxynivalenol results in decreased expression of RPL27A mRNA

NCBI chr 1:163,539,732...163,542,771

G

ribosomal protein L31

decreases expression

deoxynivalenol results in decreased expression of RPL31 mRNA

NCBI chr 9:41,647,397...41,651,441
Ensembl chr 9:41,647,426...41,662,129

G

ribosomal protein L4

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RPL4 protein

NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306

G

ribosomal protein lateral stalk subunit P0

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of RPLP0 protein

PMID:23352502 PMID:23811945

NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632

G

ribosomal protein lateral stalk subunit P1

decreases phosphorylation
increases phosphorylation

deoxynivalenol results in decreased phosphorylation of RPLP1 protein
deoxynivalenol results in increased phosphorylation of RPLP1 protein

PMID:23352502 PMID:23811945

NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339

G

ribosomal protein lateral stalk subunit P2

decreases phosphorylation
increases phosphorylation

deoxynivalenol results in decreased phosphorylation of RPLP2 protein
deoxynivalenol results in increased phosphorylation of RPLP2 protein

PMID:23352502 PMID:23811945

NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645

G

ribonuclease P/MRP subunit p30

increases expression

deoxynivalenol results in increased expression of RPP30 mRNA

NCBI chr 1:233,786,048...233,808,958
Ensembl chr 1:233,786,099...233,808,952

G

ribosomal protein S29

decreases expression

deoxynivalenol results in decreased expression of RPS29 mRNA

NCBI chr 6:87,635,229...87,636,627
Ensembl chr 6:87,635,230...87,636,636

G

ribosomal protein S6

decreases phosphorylation
multiple interactions

deoxynivalenol results in decreased phosphorylation of RPS6 protein
lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6 protein]

NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602

G

ribosomal protein S6 kinase A1

multiple interactions
increases phosphorylation

4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased phosphorylation of RPS6KA1 protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of RPS6KA1 protein

PMID:15772366 PMID:15976193

NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272

G

ribosomal protein S6 kinase A2

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RPS6KA2 protein

NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739

G

ribosomal protein S6 kinase A5

increases phosphorylation

deoxynivalenol results in increased phosphorylation of RPS6KA5 protein

NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224

G

ribosomal protein S6 kinase B1

decreases phosphorylation
multiple interactions

deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein
lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein]

NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908

G

ribonucleotide reductase regulatory TP53 inducible subunit M2B

increases expression

deoxynivalenol results in increased expression of RRM2B mRNA

NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633

G

ribosomal L1 domain containing 1

increases expression

deoxynivalenol results in increased expression of RSL1D1 mRNA

NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593

G

RuvB-like AAA ATPase 2

increases expression

deoxynivalenol results in increased expression of RUVBL2 mRNA

NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342

G

S100 calcium-binding protein A4

decreases expression

deoxynivalenol results in decreased expression of S100A4 mRNA

NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254

G

scaffold attachment factor B

increases phosphorylation

deoxynivalenol results in increased phosphorylation of SAFB protein

NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644

G

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of SAMHD1 protein

NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386

G

scavenger receptor class A, member 5

decreases expression

deoxynivalenol results in decreased expression of SCARA5 mRNA

NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373

G

sodium channel and clathrin linker 1

increases expression

deoxynivalenol results in increased expression of SCLT1 mRNA

NCBI chr 2:124,605,445...124,763,964
Ensembl chr 2:124,605,658...124,764,065

G

syndecan 1

decreases expression

deoxynivalenol results in decreased expression of SDC1 protein

NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264

G

SEC61 translocon subunit beta

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of SEC61B protein

NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804

G

semaphorin 3A

decreases expression

deoxynivalenol results in decreased expression of SEMA3A mRNA

NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432

G

serine (or cysteine) peptidase inhibitor, clade A, member 3N

decreases expression

deoxynivalenol results in decreased expression of SERPINA3 mRNA

NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433

G

serpin family E member 2

decreases expression

deoxynivalenol results in decreased expression of SERPINE2 mRNA

NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826

G

SET domain containing 1A, histone lysine methyltransferase

increases phosphorylation

deoxynivalenol results in increased phosphorylation of SETD1A protein

NCBI chr 1:182,386,197...182,411,695
Ensembl chr 1:182,388,060...182,411,090

G

splicing factor 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of SF1 protein

NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330

G

splicing factor 3A subunit 1

increases expression

deoxynivalenol results in increased expression of SF3A1 mRNA

NCBI chr14:79,031,394...79,052,144
Ensembl chr14:79,031,394...79,052,144

G

SFT2 domain containing 2

decreases expression

deoxynivalenol results in decreased expression of SFT2D2 mRNA

NCBI chr13:77,484,778...77,504,123
Ensembl chr13:77,484,636...77,504,112

G

sphingosine-1-phosphate phosphatase 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of SGPP1 protein

NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534

G

SH2 domain containing 3C

affects phosphorylation

deoxynivalenol affects the phosphorylation of SH2D3C protein

NCBI chr 3:16,010,622...16,046,491
Ensembl chr 3:16,010,625...16,046,484

G

SH3-domain binding protein 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of SH3BP1 protein

NCBI chr 7:110,457,626...110,470,201
Ensembl chr 7:110,457,710...110,470,201

G

SH3 domain-containing kinase-binding protein 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of SH3KBP1 protein

NCBI chr X:34,877,862...35,223,013
Ensembl chr X:34,877,866...35,222,747

G

SHC binding and spindle associated 1

increases expression

deoxynivalenol results in increased expression of SHCBP1 mRNA

NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844

G

SHOX homeobox 1

decreases expression

deoxynivalenol results in decreased expression of SHOX mRNA

NCBI chr X:116,688,163...116,695,111
Ensembl chr X:116,688,163...116,695,058

G

sirtuin 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of SIRT1 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of SIRT1 mRNA]

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

solute carrier family 10 member 2

multiple interactions
decreases expression

GW 4064 inhibits the reaction [deoxynivalenol results in decreased expression of SLC10A2 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in decreased expression of SLC10A2 mRNA]

PMID:35224661 PMID:37315771

NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475

G

solute carrier family 16 member 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of SLC16A1 protein

NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611

G

solute carrier family 1 member 3

affects localization

deoxynivalenol affects the localization of SLC1A3 protein

NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605

G

solute carrier family 1 member 5

decreases expression

deoxynivalenol results in decreased expression of SLC1A5 mRNA

NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952

G

solute carrier family 25 member 6

decreases expression

deoxynivalenol results in decreased expression of SLC25A6 mRNA

NCBI chr18:68,571,222...68,572,461
Ensembl chr18:68,571,300...68,572,199

G

solute carrier family 4 member 1 adaptor protein

increases expression

deoxynivalenol results in increased expression of SLC4A1AP mRNA

NCBI chr 6:24,905,941...24,933,651
Ensembl chr 6:24,905,941...24,933,815

G

solute carrier family 4 member 7

increases expression

deoxynivalenol results in increased expression of SLC4A7 mRNA

NCBI chr15:10,585,307...10,664,780
Ensembl chr15:10,588,979...10,664,781

G

solute carrier family 51 member A

decreases expression

deoxynivalenol results in decreased expression of SLC51A mRNA

NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485

G

solute carrier family 7 member 11

decreases expression
multiple interactions

deoxynivalenol results in decreased expression of SLC7A11 mRNA
Resveratrol inhibits the reaction [deoxynivalenol results in decreased expression of SLC7A11 protein]

PMID:31863870 PMID:37419272

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

increases phosphorylation

deoxynivalenol results in increased phosphorylation of SMARCC2 protein

NCBI chr 7:881,844...910,090
Ensembl chr 7:881,421...909,978

G

spermine oxidase

increases expression

deoxynivalenol results in increased expression of SMOX mRNA

NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710

G

Smad nuclear interacting protein 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of SNIP1 protein

NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845

G

SNW domain containing 1

decreases phosphorylation
increases expression

deoxynivalenol results in decreased phosphorylation of SNW1 protein
deoxynivalenol results in increased expression of SNW1 mRNA

PMID:23352502 PMID:31863870

NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536

G

suppressor of cytokine signaling 1

increases expression
multiple interactions

deoxynivalenol results in increased expression of SOCS1 mRNA
deoxynivalenol inhibits the reaction [Antigens results in increased expression of SOCS1 mRNA]

PMID:19625342 PMID:28935500

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

G

suppressor of cytokine signaling 2

increases expression
multiple interactions

deoxynivalenol results in increased expression of SOCS2 mRNA
deoxynivalenol inhibits the reaction [Antigens results in increased expression of SOCS2 mRNA]

PMID:19625342 PMID:28935500

NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548

G

suppressor of cytokine signaling 3

increases expression

deoxynivalenol results in increased expression of SOCS3 mRNA; deoxynivalenol results in increased expression of SOCS3 protein

PMID:19625342 PMID:19805407

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

superoxide dismutase 1

decreases expression
multiple interactions

deoxynivalenol results in decreased expression of SOD1 mRNA
Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of SOD1 mRNA]

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

decreases expression
increases expression

deoxynivalenol results in decreased expression of SOD2 mRNA
deoxynivalenol results in increased expression of SOD2 mRNA

PMID:20702593 PMID:35314294

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

sorbin and SH3 domain containing 2

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of SORBS2 protein

NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514

G

SRY-box transcription factor 4

increases expression

deoxynivalenol results in increased expression of SOX4 mRNA

NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665

G

SRY-box transcription factor 5

increases expression

deoxynivalenol results in increased expression of SOX5 mRNA

NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852

G

Sp1 transcription factor

multiple interactions
affects expression
increases phosphorylation

deoxynivalenol promotes the reaction [SP1 protein binds to KMT2A promoter]; SP1 protein promotes the reaction [deoxynivalenol results in increased expression of KMT2A mRNA]
deoxynivalenol affects the expression of SP1 protein
deoxynivalenol results in increased phosphorylation of SP1 protein

PMID:19438726 PMID:33890134

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

G

SP100 nuclear antigen

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of SP100 protein

NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034

G

sperm associated antigen 5

increases expression

deoxynivalenol results in increased expression of SPAG5 mRNA

NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745

G

secreted phosphoprotein 1

decreases phosphorylation
increases expression

deoxynivalenol results in decreased phosphorylation of SPP1 protein
deoxynivalenol results in increased expression of SPP1 mRNA

PMID:23352502 PMID:27757495

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

small proline-rich protein 1A

decreases expression

deoxynivalenol results in decreased expression of SPRR1A protein

NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063

G

small proline-rich protein 3

increases expression

deoxynivalenol results in increased expression of SPRR3 mRNA

NCBI chr 2:178,027,743...178,028,501
Ensembl chr 2:178,027,425...178,029,891

G

serine palmitoyltransferase, long chain base subunit 2

decreases expression

deoxynivalenol results in decreased expression of SPTLC2 mRNA

NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542

G

sequestosome 1

increases expression

deoxynivalenol results in increased expression of SQSTM1 mRNA

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

serum response factor binding protein 1

increases expression

deoxynivalenol results in increased expression of SRFBP1 mRNA

NCBI chr18:45,920,389...45,945,385
Ensembl chr18:45,920,446...45,942,515

G

serine and arginine repetitive matrix 1

increases phosphorylation
affects phosphorylation
decreases phosphorylation

deoxynivalenol results in increased phosphorylation of SRRM1 protein
deoxynivalenol affects the phosphorylation of SRRM1 protein
deoxynivalenol results in decreased phosphorylation of SRRM1 protein

PMID:23352502 PMID:23811945

NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849

G

serine/arginine repetitive matrix 2

affects phosphorylation

deoxynivalenol affects the phosphorylation of SRRM2 protein

PMID:23352502 PMID:23811945

NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751

G

serine and arginine rich splicing factor 1

decreases phosphorylation
increases phosphorylation

deoxynivalenol results in decreased phosphorylation of SRSF1 protein
deoxynivalenol results in increased phosphorylation of SRSF1 protein

PMID:23352502 PMID:23811945

NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336

G

serine and arginine rich splicing factor 2

affects phosphorylation

deoxynivalenol affects the phosphorylation of SRSF2 protein

NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338

G

serine and arginine rich splicing factor 9

decreases phosphorylation
increases phosphorylation

deoxynivalenol results in decreased phosphorylation of SRSF9 protein
deoxynivalenol results in increased phosphorylation of SRSF9 protein

PMID:23352502 PMID:23811945

NCBI chr12:41,278,225...41,284,502
Ensembl chr12:41,275,687...41,284,499

G

structure specific recognition protein 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of SSRP1 protein

NCBI chr 3:70,124,371...70,134,481
Ensembl chr 3:70,118,655...70,134,482

G

steroidogenic acute regulatory protein

multiple interactions

[Colforsin co-treated with deoxynivalenol] results in increased expression of STAR mRNA

NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672

G

signal transducer and activator of transcription 1

multiple interactions
increases expression
increases phosphorylation

[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of STAT1 mRNA; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of STAT1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT1 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of STAT1 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT1 protein]

PMID:22454431 PMID:28935500

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

signal transducer and activator of transcription 2

increases expression

deoxynivalenol results in increased expression of STAT2 mRNA

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

G

signal transducer and activator of transcription 3

multiple interactions
increases phosphorylation
increases expression

alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]

PMID:22454431 PMID:36602574

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

signal transducer and activator of transcription 4

multiple interactions

[deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of STAT4 mRNA

NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540

G

STEAP3 metalloreductase

increases phosphorylation

deoxynivalenol results in increased phosphorylation of STEAP3 protein

NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519

G

stathmin 1

increases phosphorylation

deoxynivalenol results in increased phosphorylation of STMN1 protein

PMID:23352502 PMID:23811945

NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154

G

spermatid perinuclear RNA binding protein

increases expression

deoxynivalenol results in increased expression of STRBP mRNA

NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949

G

striatin interacting protein 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of STRIP1 protein

NCBI chr 2:195,248,384...195,268,330
Ensembl chr 2:195,248,386...195,268,481

G

sulfatase 1

decreases expression

deoxynivalenol results in decreased expression of SULF1 mRNA

NCBI chr 5:6,362,894...6,526,174
Ensembl chr 5:6,362,911...6,525,584

G

syntabulin

decreases expression

deoxynivalenol results in decreased expression of SYBU mRNA

NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828

G

synemin

affects phosphorylation

deoxynivalenol affects the phosphorylation of SYNM protein

NCBI chr 1:121,333,712...121,363,652
Ensembl chr 1:121,333,720...121,363,652

G

synaptopodin 2

affects phosphorylation

deoxynivalenol affects the phosphorylation of SYNPO2 protein

NCBI chr 2:211,217,099...211,371,267
Ensembl chr 2:211,216,783...211,371,267

G

transporter 1, ATP binding cassette subfamily B member

decreases expression

deoxynivalenol results in decreased expression of TAP1 mRNA; deoxynivalenol results in decreased expression of TAP1 protein

NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901

G

TBC1 domain family, member 15

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of TBC1D15 protein

NCBI chr 7:50,804,553...50,860,272
Ensembl chr 7:50,804,012...50,860,175

G

TATA box binding protein

increases expression

deoxynivalenol results in increased expression of TBP protein

NCBI chr 1:56,463,330...56,480,430
Ensembl chr 1:56,463,618...56,510,016

G

treacle ribosome biogenesis factor 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of TCOF1 protein

NCBI chr18:54,267,015...54,300,324
Ensembl chr18:54,267,026...54,300,324

G

transferrin

multiple interactions
decreases expression

[deoxynivalenol co-treated with Zearalenone] affects the expression of TF mRNA; [deoxynivalenol co-treated with Zearalenone] results in increased expression of TF mRNA
deoxynivalenol results in decreased expression of TF mRNA

PMID:28865950 PMID:28935499

NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511

G

transcription factor AP-4

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of TFAP4 protein

NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386

G

transcription factor CP2-like 1

decreases expression

deoxynivalenol results in decreased expression of TFCP2L1 protein

NCBI chr13:29,733,813...29,793,870
Ensembl chr13:29,733,840...29,793,870

G

trefoil factor 1

affects expression
increases expression
multiple interactions
decreases secretion

deoxynivalenol affects the expression of TFF1 mRNA
deoxynivalenol results in increased expression of TFF1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [deoxynivalenol affects the expression of TFF1 mRNA]; Adenine affects the reaction [deoxynivalenol affects the expression of TFF1 mRNA]; afimoxifene inhibits the reaction [deoxynivalenol results in increased expression of TFF1 mRNA]; deoxynivalenol promotes the reaction [Estradiol results in increased expression of TFF1 mRNA]; deoxynivalenol promotes the reaction [Zearalenone results in increased expression of TFF1 mRNA]; ESR1 promotes the reaction [deoxynivalenol results in increased expression of TFF1 mRNA]; SB 203580 affects the reaction [deoxynivalenol affects the expression of TFF1 mRNA]
deoxynivalenol results in decreased secretion of TFF1 protein

PMID:30854615 PMID:35588983

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

trefoil factor 2

decreases secretion
multiple interactions
affects expression

deoxynivalenol results in decreased secretion of TFF2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [deoxynivalenol affects the expression of TFF2 mRNA]; Adenine affects the reaction [deoxynivalenol affects the expression of TFF2 mRNA]; SB 203580 affects the reaction [deoxynivalenol affects the expression of TFF2 mRNA]

NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619

G

trefoil factor 3

multiple interactions
affects expression
decreases secretion

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA]; Adenine affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA]; SB 203580 affects the reaction [deoxynivalenol affects the expression of TFF3 mRNA]
deoxynivalenol results in decreased secretion of TFF3 protein

NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054

G

transferrin receptor

increases expression

deoxynivalenol results in increased expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor, beta 1

multiple interactions
increases expression

deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TGFB1 mRNA]
deoxynivalenol results in increased expression of TGFB1 mRNA

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

transforming growth factor, beta 3

multiple interactions
increases expression

deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TGFB3 mRNA]
deoxynivalenol results in increased expression of TGFB3 mRNA

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

G

thyroid hormone receptor associated protein 3

increases phosphorylation

deoxynivalenol results in increased phosphorylation of THRAP3 protein

PMID:23352502 PMID:23811945

NCBI chr 5:138,445,284...138,487,544
Ensembl chr 5:138,445,295...138,487,477

G

thyroid hormone receptor beta

multiple interactions
decreases activity

[15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in decreased activity of THRB protein; deoxynivalenol inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]
deoxynivalenol results in decreased activity of THRB protein

PMID:27481073 PMID:31077750

NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916

G

TIMP metallopeptidase inhibitor 3

decreases expression

deoxynivalenol results in decreased expression of TIMP3 mRNA

NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839

G

tight junction protein 1

affects localization
multiple interactions
decreases expression
increases expression

deoxynivalenol affects the localization of TJP1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of and affects the localization of TJP1 protein]; Curcumin inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]; deoxynivalenol results in decreased expression of and affects the localization of TJP1 protein; lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of TJP1 protein]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 mRNA]; sodium arsenite promotes the reaction [deoxynivalenol results in decreased expression of TJP1 protein]
deoxynivalenol results in decreased expression of TJP1 mRNA; deoxynivalenol results in decreased expression of TJP1 protein
deoxynivalenol results in increased expression of TJP1 mRNA

PMID:24568843 PMID:34506767 PMID:35381244 PMID:35817260

NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432

G

toll-like receptor 1

decreases expression

deoxynivalenol results in decreased expression of TLR1 mRNA

NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125

G

toll-like receptor 2

decreases expression

deoxynivalenol results in decreased expression of TLR2 mRNA

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

toll-like receptor 3

decreases expression

deoxynivalenol results in decreased expression of TLR3 mRNA

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

G

toll-like receptor 4

increases expression

deoxynivalenol results in increased expression of TLR4 mRNA; deoxynivalenol results in increased expression of TLR4 protein

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

toll-like receptor 5

increases expression

deoxynivalenol results in increased expression of TLR5 mRNA

NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738

G

transmembrane 9 superfamily member 3

decreases expression

deoxynivalenol results in decreased expression of TM9SF3 mRNA

NCBI chr 1:240,032,060...240,085,125
Ensembl chr 1:240,035,003...240,084,776

G

transmembrane BAX inhibitor motif containing 6

decreases expression

deoxynivalenol results in decreased expression of TMBIM6 protein

NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633

G

thymopoietin

affects phosphorylation

deoxynivalenol affects the phosphorylation of TMPO protein

NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727

G

tumor necrosis factor

multiple interactions
increases secretion
increases expression
increases stability

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased secretion of TNF protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]]; [deoxynivalenol results in increased susceptibility to Antigens] which results in increased expression of TNF protein; [Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of TNF protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; BMAL1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Dichlororibofuranosylbenzimidazole inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; HCK protein affects the reaction [deoxynivalenol results in increased expression of TNF protein]; HMOX1 protein inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Lipopolysaccharides promotes the reaction [deoxynivalenol results in increased expression of TNF protein]; Poly I-C promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; pyrazolanthrone inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; resiquimod promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Rolipram inhibits the reaction [[Lipopolysaccharides co-treated with deoxynivalenol] results in increased expression of TNF protein]; SB 203580 inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; SB 203580 inhibits the reaction [deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased secretion of TNF protein]; sodium arsenite promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Zymosan promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]
deoxynivalenol results in increased expression of TNF mRNA; deoxynivalenol results in increased expression of TNF protein
Bentonite inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Bentonite inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Charcoal inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; deoxynivalenol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; Adenine inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased abundance of Nitric Oxide]; deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]; lactacystin inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; SB 203580 inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]
deoxynivalenol results in increased stability of TNF mRNA

PMID:9194413 PMID:9707511 PMID:10344227 PMID:11295263 PMID:11922776 More...

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

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TNF superfamily member 14

increases expression

deoxynivalenol results in increased expression of TNFSF14 mRNA

NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216

G

TNF superfamily member 9

decreases expression

deoxynivalenol results in decreased expression of TNFSF9 mRNA

NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345

G

tensin 1

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of TNS1 protein

NCBI chr 9:75,491,886...75,702,853
Ensembl chr 9:75,495,814...75,703,225

G

translocase of outer mitochondrial membrane 20

affects localization
increases phosphorylation

deoxynivalenol affects the localization of TOMM20 protein
deoxynivalenol results in increased phosphorylation of TOMM20 protein

NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198

G

translocase of outer mitochondrial membrane 22

decreases expression

deoxynivalenol results in decreased expression of TOMM22 protein

NCBI chr 7:111,223,508...111,228,671
Ensembl chr 7:111,216,571...111,246,799

G

translocase of outer mitochondrial membrane 40

decreases expression

deoxynivalenol results in decreased expression of TOMM40 protein

NCBI chr 1:79,358,781...79,370,882
Ensembl chr 1:79,358,786...79,370,915

G

translocase of outer mitochondrial membrane 70

increases phosphorylation
decreases expression

deoxynivalenol results in increased phosphorylation of TOMM70A protein
deoxynivalenol results in decreased expression of TOMM70A protein

PMID:23352502 PMID:33890134

NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202

G

DNA topoisomerase II beta

increases phosphorylation

deoxynivalenol results in increased phosphorylation of TOP2B protein

NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085

G

tumor protein p53

multiple interactions
increases expression
decreases expression
increases activity

[pifithrin results in decreased activity of TP53 protein] which results in decreased susceptibility to deoxynivalenol; Curcumin inhibits the reaction [deoxynivalenol results in increased expression of TRP53 protein]; deoxynivalenol results in increased phosphorylation of and results in increased activity of TRP53 protein; pifithrin inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased activity of TRP53 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased phosphorylation of and results in increased activity of TRP53 protein]
deoxynivalenol results in decreased expression of TP53 protein
deoxynivalenol results in increased expression of TP53 mRNA
[Zearalenone co-treated with Aflatoxin B1] promotes the reaction [deoxynivalenol results in increased expression of TP53 mRNA]; Aflatoxin B1 promotes the reaction [deoxynivalenol results in increased expression of TP53 mRNA]
deoxynivalenol results in increased activity of TP53 protein

PMID:15976193 PMID:19664677 PMID:22491426 PMID:30668976 PMID:33890134 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

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tumor protein p53 inducible nuclear protein 1

increases expression

deoxynivalenol results in increased expression of TP53INP1 mRNA

NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968

G

TNF receptor-associated factor 1

increases expression

deoxynivalenol results in increased expression of TRAF1 mRNA

NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807

G

TNF receptor associated factor 6

increases expression

deoxynivalenol results in increased expression of TRAF6 mRNA

PMID:22846391 PMID:34400200

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

G

tribbles pseudokinase 3

decreases expression

deoxynivalenol results in decreased expression of TRIB3 mRNA

PMID:23253260 PMID:31863870

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

tripartite motif-containing 28

increases phosphorylation

deoxynivalenol results in increased phosphorylation of TRIM28 protein

NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380

G

tRNA methyltransferase 13 homolog

increases expression

deoxynivalenol results in increased expression of TRMT13 mRNA

NCBI chr 2:204,533,630...204,547,711
Ensembl chr 2:204,533,632...204,546,843

G

transient receptor potential cation channel, subfamily A, member 1

multiple interactions

TRPA1 affects the reaction [deoxynivalenol results in increased secretion of CCK protein]

NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570

G

thymic stromal lymphopoietin

multiple interactions

deoxynivalenol promotes the reaction [Antigens, Dermatophagoides results in increased expression of TSLP protein]

NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548

G

Ttk protein kinase

increases expression

deoxynivalenol results in increased expression of TTK mRNA

NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651

G

thioredoxin domain containing 11

decreases expression

deoxynivalenol results in decreased expression of TXNDC11 mRNA

NCBI chr10:4,515,457...4,572,999
Ensembl chr10:4,515,478...4,572,989

G

thioredoxin domain containing 16

increases phosphorylation

deoxynivalenol results in increased phosphorylation of TXNDC16 protein

NCBI chr15:18,351,688...18,425,833
Ensembl chr15:18,351,694...18,425,722

G

ubiquitin-conjugating enzyme E2C

increases expression

deoxynivalenol results in increased expression of UBE2C mRNA

NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339

G

UDP glucuronosyltransferase family 2 member B7

increases glucuronidation

UGT2B7 protein results in increased glucuronidation of deoxynivalenol

NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604

G

ubiquitin-like with PHD and ring finger domains 1

affects phosphorylation

deoxynivalenol affects the phosphorylation of UHRF1 protein

NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631

G

unc-13 homolog D

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of UNC13D protein

NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687

G

UPF2, regulator of nonsense mediated mRNA decay

increases expression

deoxynivalenol results in increased expression of UPF2 mRNA

NCBI chr17:72,224,575...72,335,896
Ensembl chr17:72,225,316...72,335,855

G

UPF3B, regulator of nonsense mediated mRNA decay

increases expression

deoxynivalenol results in increased expression of UPF3B mRNA

NCBI chr X:116,335,308...116,353,332
Ensembl chr X:116,335,308...116,353,236

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ubiquinol-cytochrome c reductase core protein 1

decreases expression

deoxynivalenol results in decreased expression of UQCRC1 protein

NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480

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ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

decreases expression

deoxynivalenol results in decreased expression of UQCRFS1 protein

NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479

G

ubiquitin specific peptidase 15

increases expression

deoxynivalenol results in increased expression of USP15 mRNA

NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721

G

ubiquitin specific peptidase 24

increases phosphorylation

deoxynivalenol results in increased phosphorylation of USP24 protein

NCBI chr 5:121,080,687...121,210,321
Ensembl chr 5:121,080,470...121,210,311

G

ubiquitin specific peptidase 30

increases expression

deoxynivalenol results in increased expression of USP30 mRNA

NCBI chr12:42,501,345...42,555,311
Ensembl chr12:42,501,348...42,555,616

G

ubiquitin specific peptidase 39

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of USP39 protein

NCBI chr 4:104,373,948...104,406,359
Ensembl chr 4:104,373,955...104,406,359

G

UTP3, small subunit processome component

increases expression

deoxynivalenol results in increased expression of UTP3 mRNA

NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396

G

vesicle-associated membrane protein 4

increases expression

deoxynivalenol results in increased expression of VAMP4 mRNA

NCBI chr13:74,919,872...74,942,791
Ensembl chr13:74,919,880...74,933,686

G

versican

decreases expression

deoxynivalenol results in decreased expression of VCAN mRNA

NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637

G

villin 1

multiple interactions
decreases expression

lauric acid inhibits the reaction [deoxynivalenol results in decreased expression of VIL1 protein]

NCBI chr 9:75,991,141...76,018,860
Ensembl chr 9:75,991,141...76,018,858

G

tryptophanyl-tRNA synthetase 1

decreases expression

deoxynivalenol results in decreased expression of WARS1 mRNA

NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269

G

WASH complex subunit 2C

increases phosphorylation

deoxynivalenol results in increased phosphorylation of WASHC2 protein

NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851

G

WW domain binding protein 4

increases expression

deoxynivalenol results in increased expression of WBP4 mRNA

NCBI chr15:54,862,700...54,890,668
Ensembl chr15:54,862,843...54,890,647

G

WD repeat domain 20

increases expression

deoxynivalenol results in increased expression of WDR20 mRNA

NCBI chr 6:129,751,952...129,821,464
Ensembl chr 6:129,752,014...129,847,339

G

WD repeat domain 5

increases expression

deoxynivalenol results in increased expression of WDR5 mRNA

NCBI chr 3:10,836,964...10,856,682
Ensembl chr 3:10,837,025...10,856,671

G

WD repeat domain 74

increases expression

deoxynivalenol results in increased expression of WDR74 mRNA

NCBI chr 1:205,631,769...205,636,558
Ensembl chr 1:205,631,824...205,636,563

G

WAP four-disulfide core domain 1

decreases expression

deoxynivalenol results in decreased expression of WFDC1 mRNA

NCBI chr19:47,720,191...47,739,121
Ensembl chr19:47,720,423...47,739,108

G

WD repeat domain, phosphoinositide interacting 1

decreases expression

deoxynivalenol results in decreased expression of WIPI1 mRNA

NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846

G

WD repeat containing, antisense to TP53

increases expression

deoxynivalenol results in increased expression of WRAP53 mRNA

NCBI chr10:54,282,092...54,299,908
Ensembl chr10:54,282,105...54,298,929

G

WW domain containing transcription regulator 1

increases expression

deoxynivalenol results in increased expression of WWTR1 protein

NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968

G

X-box binding protein 1

increases expression
increases splicing

deoxynivalenol results in increased expression of XBP1 protein
deoxynivalenol results in increased splicing of XBP1 mRNA

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

G

X-ray repair cross complementing 1

increases expression

deoxynivalenol results in increased expression of XRCC1 mRNA; deoxynivalenol results in increased expression of XRCC1 protein

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

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Yes1 associated transcriptional regulator

decreases phosphorylation

deoxynivalenol results in decreased phosphorylation of YAP1 protein

NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010

G

zinc finger and BTB domain containing 11

increases expression

deoxynivalenol results in increased expression of ZBTB11 mRNA

NCBI chr11:44,598,694...44,652,559
Ensembl chr11:44,616,289...44,651,050

G

zinc finger and BTB domain containing 18

increases expression

deoxynivalenol results in increased expression of ZBTB18 mRNA

NCBI chr13:89,439,501...89,447,958
Ensembl chr13:89,439,420...89,448,862

G

zinc finger and BTB domain containing 21

increases expression

deoxynivalenol results in increased expression of ZBTB21 mRNA

NCBI chr11:37,312,337...37,327,040
Ensembl chr11:37,312,378...37,326,996

G

zinc finger and BTB domain containing 33

increases expression

deoxynivalenol results in increased expression of ZBTB33 mRNA

NCBI chr X:116,963,337...116,970,547
Ensembl chr X:116,963,347...116,971,023

G

zinc finger CCCH-type containing 11A

increases phosphorylation

deoxynivalenol results in increased phosphorylation of ZC3H11A protein

NCBI chr13:45,073,422...45,113,901
Ensembl chr13:45,071,718...45,114,009

G

zinc finger CCHC-type containing 4

increases expression

deoxynivalenol results in increased expression of ZCCHC4 mRNA

NCBI chr14:58,165,467...58,207,071
Ensembl chr14:58,165,460...58,206,743

G

zinc finger E-box binding homeobox 1

decreases activity
multiple interactions

deoxynivalenol results in decreased activity of ZEB1 protein
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [deoxynivalenol results in decreased expression of ZEB1 protein]

NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214

G

zinc finger E-box binding homeobox 2

increases expression

deoxynivalenol results in increased expression of ZEB2 mRNA

NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157

G

zinc finger protein 354C

decreases expression

deoxynivalenol results in decreased expression of ZNF354C protein

NCBI chr10:35,129,720...35,145,717
Ensembl chr10:35,132,959...35,145,661

G

zinc finger protein 777

increases expression

deoxynivalenol results in increased expression of ZNF777 mRNA

NCBI chr 4:77,016,377...77,044,008
Ensembl chr 4:77,016,363...77,047,020

Deoxynivalenol 3-glucoside

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

interleukin 1 beta

increases expression

deoxynivalenol-3-glucoside results in increased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

increases expression

deoxynivalenol-3-glucoside results in increased expression of IL6 mRNA

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Diacetoxyscirpenol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

activity-regulated cytoskeleton-associated protein

decreases expression

diacetoxyscirpenol results in decreased expression of ARC mRNA

NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378

G

caspase 12

decreases expression

diacetoxyscirpenol results in decreased expression of CASP12 mRNA

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 9

decreases expression

diacetoxyscirpenol results in decreased expression of CASP9 mRNA

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

cyclin B1

decreases expression

diacetoxyscirpenol results in decreased expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin-dependent kinase 4

decreases expression

diacetoxyscirpenol results in decreased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 2A

decreases expression

diacetoxyscirpenol results in decreased expression of CDKN2A mRNA

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cholinergic receptor nicotinic alpha 7 subunit

decreases expression

diacetoxyscirpenol results in decreased expression of CHRNA7 mRNA

NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240

G

gastric inhibitory polypeptide

multiple interactions

diacetoxyscirpenol results in increased expression of and results in increased secretion of GIP protein

NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503

G

glutamate ionotropic receptor AMPA type subunit 1

increases expression

diacetoxyscirpenol results in increased expression of GRIA1 mRNA

NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283

G

glutamate ionotropic receptor AMPA type subunit 2

increases expression

diacetoxyscirpenol results in increased expression of GRIA2 mRNA

NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510

G

glutamate ionotropic receptor AMPA type subunit 3

decreases expression

diacetoxyscirpenol results in decreased expression of GRIA3 mRNA

NCBI chr X:120,238,515...120,504,106
Ensembl chr X:120,238,534...120,504,096

G

glutamate ionotropic receptor NMDA type subunit 2A

decreases expression

diacetoxyscirpenol results in decreased expression of GRIN2A mRNA

NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637

G

intersectin 1

increases expression

diacetoxyscirpenol results in increased expression of ITSN1 mRNA

NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645

G

KIT proto-oncogene receptor tyrosine kinase

decreases expression

diacetoxyscirpenol results in decreased expression of KIT mRNA

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

G

8-oxoguanine DNA glycosylase

decreases expression

diacetoxyscirpenol results in decreased expression of OGG1 mRNA

NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766

G

poly (ADP-ribose) polymerase 1

decreases expression

diacetoxyscirpenol results in decreased expression of PARP1 mRNA

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

prostaglandin-endoperoxide synthase 2

decreases expression

diacetoxyscirpenol results in decreased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

RB transcriptional corepressor 1

decreases expression

diacetoxyscirpenol results in decreased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

solute carrier family 17 member 6

increases expression

diacetoxyscirpenol results in increased expression of SLC17A6 mRNA

NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542

G

solute carrier family 17 member 7

decreases expression

diacetoxyscirpenol results in decreased expression of SLC17A7 mRNA

NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588

G

tumor protein p53

decreases expression

diacetoxyscirpenol results in decreased expression of TRP53 mRNA

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

Fusarenone X

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

decreases activity

fusarenon-X results in decreased activity of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

activating transcription factor 6

increases expression

fusarenon-X results in increased expression of ATF6 mRNA

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

BCL2-associated agonist of cell death

increases expression

fusarenon-X results in increased expression of BAD mRNA

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

BCL2 associated X, apoptosis regulator

increases expression

fusarenon-X results in increased expression of BAX mRNA

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

increases expression
decreases expression

fusarenon-X results in increased expression of BCL2 mRNA
fusarenon-X results in decreased expression of BCL2 mRNA

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL2-related protein A1

increases expression

fusarenon-X results in increased expression of BCL2A1B mRNA

NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998

G

Bcl2-like 1

increases expression

fusarenon-X results in increased expression of BCL2L1 mRNA

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

Bcl2-like 2

increases expression

fusarenon-X results in increased expression of BCL2L2 mRNA

NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624

G

BH3 interacting domain death agonist

decreases expression

fusarenon-X results in decreased expression of BID mRNA

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

caspase 4

increases expression

fusarenon-X results in increased expression of CASP4 mRNA

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

caspase 8

increases expression

fusarenon-X results in increased expression of CASP8 mRNA

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

increases expression

fusarenon-X results in increased expression of CASP9 mRNA

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

cholecystokinin

increases expression

fusarenon-X results in increased expression of CCK protein

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

C-C motif chemokine ligand 2

increases expression

fusarenon-X results in increased expression of CCL2 mRNA

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 7

increases expression

fusarenon-X results in increased expression of CCL7 mRNA

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

CD40 ligand

decreases expression

fusarenon-X results in decreased expression of CD40LG mRNA

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

G

C-X-C motif chemokine ligand 2

increases expression

fusarenon-X results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

eukaryotic translation initiation factor 2A

increases phosphorylation

fusarenon-X results in increased phosphorylation of EIF2A protein

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

Fas cell surface death receptor

increases expression

fusarenon-X results in increased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

decreases expression

fusarenon-X results in decreased expression of FASL mRNA

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

granzyme B

increases expression

fusarenon-X results in increased expression of GZMB mRNA

NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814

G

heat shock protein family A (Hsp70) member 5

decreases expression

fusarenon-X results in decreased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

interleukin 1 beta

increases expression

fusarenon-X results in increased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

increases expression

fusarenon-X results in increased expression of IL6 mRNA

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interferon regulatory factor 2

increases expression

fusarenon-X results in increased expression of IRF2 mRNA

NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024

G

mitogen-activated protein kinase kinase kinase 14

increases expression

fusarenon-X results in increased expression of MAP3K14 mRNA

NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523

G

NFKB inhibitor epsilon

increases expression

fusarenon-X results in increased expression of NFKBIE mRNA

NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437

G

nerve growth factor

increases expression

fusarenon-X results in increased expression of NGF mRNA

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

nerve growth factor receptor

decreases expression

fusarenon-X results in decreased expression of NGFR mRNA; fusarenon-X results in decreased expression of TNFRSF10B mRNA

NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518

G

nuclear receptor subfamily 3, group C, member 1

decreases expression

fusarenon-X results in decreased expression of NR3C1 mRNA

NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375

G

peroxisome proliferator-activated receptor gamma

decreases activity

fusarenon-X results in decreased activity of PPARG protein

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

prostaglandin-endoperoxide synthase 2

increases expression

fusarenon-X results in increased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

tumor necrosis factor

increases expression

fusarenon-X results in increased expression of TNF mRNA

PMID:24793808 PMID:24983900

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 1B

increases expression

fusarenon-X results in increased expression of TNFRSF1B mRNA

NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206

G

TNF superfamily member 10

increases expression

fusarenon-X results in increased expression of TNFSF10 mRNA

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

G

tumor protein p53

increases expression

fusarenon-X results in increased expression of TRP53 mRNA

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tumor protein p63

decreases expression

fusarenon-X results in decreased expression of TRP63 mRNA

NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398

G

tumor protein p73

increases expression

fusarenon-X results in increased expression of TRP73 mRNA

NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128

G

TNF receptor-associated factor 1

increases expression

fusarenon-X results in increased expression of TRAF1 mRNA

NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807

G

Tnf receptor-associated factor 3

decreases expression

fusarenon-X results in decreased expression of TRAF3 mRNA

NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481

G

TNF receptor associated factor 6

increases expression

fusarenon-X results in increased expression of TRAF6 mRNA

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

G

X-linked inhibitor of apoptosis

decreases expression

fusarenon-X results in decreased expression of XIAP mRNA

NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700

HT-2 toxin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

increases activity

HT-2 toxin results in increased activity of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

cytochrome P450, family 11, subfamily a, polypeptide 1

decreases expression

HT-2 toxin results in decreased expression of CYP11A mRNA

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases expression

HT-2 toxin results in decreased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases expression

HT-2 toxin results in decreased expression of CYP19A1 mRNA

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

HT-2 toxin results in increased expression of CYP1A1 mRNA

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

epoxide hydrolase 1

increases expression

HT-2 toxin results in increased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

gastric inhibitory polypeptide

multiple interactions

HT-2 toxin results in increased expression of and results in increased secretion of GIP protein

NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

HT-2 toxin results in decreased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

hydroxysteroid (17-beta) dehydrogenase 1

increases expression

HT-2 toxin results in increased expression of HSD17B1 mRNA

NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927

Neosolaniol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

increases activity

neosolaniol results in increased activity of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

gastric inhibitory polypeptide

multiple interactions

neosolaniol results in increased expression of and results in increased secretion of GIP protein

NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503

Nivalenol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

decreases activity

nivalenol results in decreased activity of AR protein

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

activating transcription factor 3

increases expression

nivalenol results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 6

increases expression

nivalenol results in increased expression of ATF6 mRNA

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

ATP synthase F1 subunit alpha

decreases expression

nivalenol results in decreased expression of ATP5F1A mRNA

NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794

G

ATPase H+ transporting accessory protein 2

increases expression

nivalenol results in increased expression of ATP6AP2 mRNA

NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918

G

BCL2 associated X, apoptosis regulator

increases expression

nivalenol results in increased expression of BAX protein

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

branched chain amino acid transaminase 2

decreases expression

nivalenol results in decreased expression of BCAT2 mRNA

NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007

G

Bet1 golgi vesicular membrane trafficking protein

decreases expression

nivalenol results in decreased expression of BET1 mRNA

NCBI chr 4:32,116,232...32,126,592
Ensembl chr 4:32,116,235...32,126,617

G

BMS1 ribosome biogenesis factor

decreases expression

nivalenol results in decreased expression of BMS1 mRNA

NCBI chr 4:151,558,163...151,595,187
Ensembl chr 4:151,558,163...151,595,127

G

caspase 3

increases cleavage

nivalenol results in increased cleavage of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

cholecystokinin

increases expression

nivalenol results in increased expression of CCK protein

NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084

G

C-C motif chemokine ligand 2

increases expression

nivalenol results in increased expression of CCL2 mRNA

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

calcium homeostasis endoplasmic reticulum protein

increases expression

nivalenol results in increased expression of CHERP mRNA

NCBI chr16:17,367,455...17,380,507
Ensembl chr16:17,367,455...17,380,507

G

chloride intracellular channel 4

decreases expression

nivalenol results in decreased expression of CLIC4 mRNA

NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452

G

clustered mitochondria homolog

increases expression

nivalenol results in increased expression of CLUH mRNA

NCBI chr10:59,509,580...59,531,345
Ensembl chr10:59,509,726...59,531,345

G

component of oligomeric golgi complex 3

increases expression

nivalenol results in increased expression of COG3 mRNA

NCBI chr15:51,020,808...51,071,288
Ensembl chr15:51,020,813...51,070,570

G

C-X-C motif chemokine ligand 2

increases expression

nivalenol results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

eukaryotic translation initiation factor 2A

increases phosphorylation

nivalenol results in increased phosphorylation of EIF2A protein

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

EMAP like 4

decreases expression

nivalenol results in decreased expression of EML4 mRNA

NCBI chr 6:11,219,545...11,334,824
Ensembl chr 6:11,219,566...11,334,879

G

endoplasmic reticulum metallopeptidase 1

increases expression

nivalenol results in increased expression of ERMP1 mRNA

NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909

G

endoplasmic reticulum to nucleus signaling 1

increases expression

nivalenol results in increased expression of ERN1 mRNA

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

FRY microtubule binding protein

decreases expression

nivalenol results in decreased expression of FRY mRNA

NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116

G

guided entry of tail-anchored proteins factor 4

decreases expression

nivalenol results in decreased expression of GET4 mRNA

NCBI chr12:15,377,009...15,394,238
Ensembl chr12:15,377,009...15,394,053

G

growth hormone 1

decreases expression
multiple interactions

nivalenol results in decreased expression of GH1 mRNA
nivalenol results in decreased expression of and results in decreased secretion of GH1 protein

NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078

G

golgin A4

decreases expression

nivalenol results in decreased expression of GOLGA4 mRNA

NCBI chr 8:118,208,200...118,285,003

G

golgi phosphoprotein 3

increases expression

nivalenol results in increased expression of GOLPH3 mRNA

NCBI chr 2:61,348,030...61,376,051
Ensembl chr 2:61,348,030...61,376,049

G

golgi associated PDZ and coiled-coil motif containing

increases expression

nivalenol results in increased expression of GOPC mRNA

NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903

G

glycerol-3-phosphate dehydrogenase 2

increases expression

nivalenol results in increased expression of GPD2 mRNA

NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression

nivalenol results in increased expression of HERPUD1 mRNA

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

hook microtubule-tethering protein 1

increases expression

nivalenol results in increased expression of HOOK1 mRNA

NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787

G

hook microtubule-tethering protein 2

increases expression

nivalenol results in increased expression of HOOK2 mRNA

NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181

G

heat shock protein family A (Hsp70) member 5

decreases expression

nivalenol results in decreased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

interferon beta 1

multiple interactions

nivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IFNB1 mRNA]

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

affects expression

nivalenol affects the expression of IFNG mRNA

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 1 beta

increases expression

nivalenol results in increased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

affects expression
affects secretion
increases expression

nivalenol affects the expression of IL2 mRNA
nivalenol affects the secretion of IL2 protein
nivalenol results in increased expression of IL2 mRNA

PMID:8560498 PMID:17166736

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 4

affects secretion
increases expression

nivalenol affects the secretion of IL4 protein
nivalenol results in increased expression of IL4 mRNA

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 5

affects secretion

nivalenol affects the secretion of IL5 protein

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

KDEL endoplasmic reticulum protein retention receptor 2

increases expression

nivalenol results in increased expression of KDELR2 mRNA

NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153

G

lysosomal-associated membrane protein 2

increases expression

nivalenol results in increased expression of LAMP2 mRNA

NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522

G

microtubule-actin crosslinking factor 1

decreases expression

nivalenol results in decreased expression of MACF1 mRNA

NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905

G

microtubule-associated protein 1 light chain 3 beta

decreases expression

nivalenol results in decreased expression of MAP1LC3B mRNA

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

microtubule-associated protein 2

increases expression

nivalenol results in increased expression of MAP2 mRNA

NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809

G

microtubule-associated protein 4

increases expression

nivalenol results in increased expression of MAP4 mRNA

NCBI chr 8:109,925,233...110,064,370
Ensembl chr 8:109,925,575...110,064,362

G

microtubule-associated protein, RP/EB family, member 1

increases expression

nivalenol results in increased expression of MAPRE1 mRNA

NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983

G

microtubule-associated protein, RP/EB family, member 2

increases expression

nivalenol results in increased expression of MAPRE2 mRNA

NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044

G

microtubule affinity regulating kinase 2

increases expression

nivalenol results in increased expression of MARK2 mRNA

NCBI chr 1:204,461,029...204,526,247
Ensembl chr 1:204,461,030...204,525,652

G

microtubule associated serine/threonine kinase 2

decreases expression

nivalenol results in decreased expression of MAST2 mRNA

NCBI chr 5:129,776,293...129,915,502
Ensembl chr 5:129,775,676...129,915,606

G

microtubule interacting and trafficking domain containing 1

increases expression

nivalenol results in increased expression of MITD1 mRNA

NCBI chr 9:40,113,943...40,125,280
Ensembl chr 9:40,113,946...40,125,289

G

mucin 5AC, oligomeric mucus/gel-forming

multiple interactions
increases expression

nivalenol results in increased expression of and results in increased secretion of MUC5AC protein
nivalenol results in increased expression of MUC5AC mRNA

NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475

G

mucin 5B, oligomeric mucus/gel-forming

increases expression
multiple interactions

nivalenol results in increased expression of MUC5B mRNA
nivalenol results in increased expression of and results in increased secretion of MUC5B protein

NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250

G

nitric oxide synthase 2

multiple interactions

nivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; nivalenol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

poly (ADP-ribose) polymerase 1

increases cleavage

nivalenol results in increased cleavage of PARP1 protein

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

peroxisome proliferator-activated receptor gamma

decreases activity

nivalenol results in decreased activity of PPARG protein

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

RAB11a, member RAS oncogene family

increases expression

nivalenol results in increased expression of RAB11A protein

NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525

G

TPX2, microtubule nucleation factor

increases expression

nivalenol results in increased expression of TPX2 mRNA

NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468

G

tubulin, alpha 1B

decreases acetylation

nivalenol results in decreased acetylation of TUBA1B protein

NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186

G

WASP homolog associated with actin, golgi membranes and microtubules

increases expression

nivalenol results in increased expression of WHAMM mRNA

NCBI chr 1:135,526,363...135,557,091
Ensembl chr 1:135,526,386...135,554,759

Roridin A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

BCL2 associated X, apoptosis regulator

increases expression

roridin A results in increased expression of BAX mRNA

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

C-X-C motif chemokine ligand 2

multiple interactions
increases expression

lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [roridin A results in increased expression of CXCL2 mRNA]; roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CXCL2 mRNA]

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

DNA fragmentation factor subunit beta

increases expression

roridin A results in increased expression of DFFB mRNA

NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628

G

eukaryotic translation initiation factor 2-alpha kinase 2

multiple interactions
increases expression

lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [roridin A results in increased expression of EIF2AK2 mRNA]; roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of EIF2AK2 mRNA]

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

G

Fas cell surface death receptor

multiple interactions
increases expression

roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of FAS mRNA]
roridin A results in increased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

multiple interactions

roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of FASL mRNA]

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

heat shock protein family A (Hsp70) member 5

multiple interactions

roridin A results in increased degradation of and results in decreased expression of HSPA5 protein

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

interleukin 1 alpha

increases expression
multiple interactions

roridin A results in increased expression of IL1A mRNA
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with roridin A] affects the expression of IL1A mRNA

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

increases expression
multiple interactions

roridin A results in increased expression of IL1B mRNA
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with roridin A] affects the expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions
increases expression

lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [roridin A results in increased expression of IL6 mRNA]; roridin A promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

tumor necrosis factor

multiple interactions
increases expression

[lipopolysaccharide, Escherichia coli O111 B4 co-treated with roridin A] affects the expression of TNF mRNA
roridin A results in increased expression of TNF mRNA

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

tumor protein p53

increases expression

roridin A results in increased expression of TRP53 mRNA

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

Satratoxin H

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

caspase 3

multiple interactions
increases cleavage

pyrazolanthrone inhibits the reaction [satratoxin H results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [satratoxin H results in increased cleavage of CASP3 protein]

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

H2A.X variant histone

increases phosphorylation

satratoxin H results in increased phosphorylation of H2AX protein

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

poly (ADP-ribose) polymerase 1

increases cleavage

satratoxin H results in increased cleavage of PARP1 protein

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

T-2 toxin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

multiple interactions
decreases expression

Selenium inhibits the reaction [T-2 Toxin results in decreased expression of A2M mRNA]; Selenium promotes the reaction [T-2 Toxin results in decreased expression of A2M protein]
T-2 Toxin results in decreased expression of A2M mRNA; T-2 Toxin results in decreased expression of A2M protein

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

alanyl-tRNA synthetase 1

decreases expression

T-2 Toxin results in decreased expression of AARS1 mRNA

PMID:26141394 PMID:34581912

NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147

G

ATP binding cassette subfamily B member 1A

decreases expression

T-2 Toxin results in decreased expression of ABCB1A mRNA

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

abraxas 2, BRISC complex subunit

increases expression

T-2 Toxin results in increased expression of ABRAXAS2 mRNA

NCBI chr 1:187,647,078...187,672,660
Ensembl chr 1:187,647,067...187,672,655

G

aggrecan

decreases expression

T-2 Toxin results in decreased expression of ACAN mRNA; T-2 Toxin results in decreased expression of ACAN protein

PMID:16624732 PMID:18196609 PMID:22800716 PMID:31863870

NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627

G

acetyl-CoA acetyltransferase 2

affects expression

T-2 Toxin affects the expression of ACAT2 protein

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

ATP citrate lyase

decreases expression

T-2 Toxin results in decreased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

aconitase 2

affects expression

T-2 Toxin affects the expression of ACO2 protein

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

actin, beta

affects expression

T-2 Toxin affects the expression of ACTB protein

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin related protein 1A

increases expression

T-2 Toxin results in increased expression of ACTR1A mRNA; T-2 Toxin results in increased expression of ACTR1A protein

NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495

G

ADAM metallopeptidase domain 9

decreases expression

T-2 Toxin results in decreased expression of ADAM9 mRNA

NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917

G

ADAM metallopeptidase with thrombospondin type 1 motif, 4

increases expression

T-2 Toxin results in increased expression of ADAMTS4 mRNA

NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

increases expression

T-2 Toxin results in increased expression of ADAMTS5 mRNA

PMID:18196609 PMID:22800716

NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205

G

adenosine kinase

decreases expression

T-2 Toxin results in decreased expression of ADK protein

NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510

G

ADP-ribosylarginine hydrolase

affects expression

T-2 Toxin affects the expression of ADPRH protein

NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931

G

AFG1 like ATPase

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to AFG1L]

NCBI chr20:45,798,344...45,967,997
Ensembl chr20:45,798,349...45,967,906

G

AFG2 AAA ATPase homolog A

increases expression

T-2 Toxin results in increased expression of AFG2A mRNA

NCBI chr 2:120,306,417...120,497,707
Ensembl chr 2:120,306,412...120,497,705

G

adenosylhomocysteinase

increases expression

T-2 Toxin results in increased expression of AHCY protein

NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393

G

aryl hydrocarbon receptor

decreases expression

T-2 Toxin results in decreased expression of AHR protein

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

increases expression

T-2 Toxin results in increased expression of AIMP2 mRNA

NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769

G

adenylate kinase 2

increases expression

T-2 Toxin results in increased expression of AK2 mRNA

NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632

G

A-kinase anchoring protein 3

increases expression

T-2 Toxin results in increased expression of AKAP3 mRNA

NCBI chr 4:159,688,049...159,714,067
Ensembl chr 4:159,699,289...159,713,903

G

A-kinase anchoring protein 4

increases expression

T-2 Toxin results in increased expression of AKAP4 mRNA

NCBI chr X:15,435,391...15,445,684
Ensembl chr X:15,435,410...15,445,684

G

akirin 2

increases expression

T-2 Toxin results in increased expression of AKIRIN2 mRNA

PMID:26141394 PMID:34581912

NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568

G

AT-hook transcription factor

decreases expression
multiple interactions
affects localization

T-2 Toxin results in decreased expression of AKNA mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter]; T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter]
T-2 Toxin affects the localization of AKNA protein

PMID:26141394 PMID:29079362

NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017

G

AKT serine/threonine kinase 1

decreases expression

T-2 Toxin results in decreased expression of AKT1 mRNA

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

AKT1 substrate 1

increases expression

T-2 Toxin results in increased expression of AKT1S1 mRNA

NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677

G

5'-aminolevulinate synthase 1

increases expression

T-2 Toxin results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

5'-aminolevulinate synthase 2

increases expression

T-2 Toxin results in increased expression of ALAS2 mRNA

NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519

G

aldehyde dehydrogenase 1 family, member A1

affects expression
increases expression

T-2 Toxin affects the expression of ALDH1A1 protein
T-2 Toxin results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldolase, fructose-bisphosphate C

decreases expression

T-2 Toxin results in decreased expression of ALDOC mRNA

NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066

G

alkaline phosphatase, biomineralization associated

decreases expression

T-2 Toxin results in decreased expression of ALPL protein

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

angiopoietin like 7

decreases expression

T-2 Toxin results in decreased expression of ANGPTL7 mRNA

NCBI chr 5:158,932,096...158,937,281
Ensembl chr 5:158,932,794...158,937,324

G

anillin, actin binding protein

decreases expression

T-2 Toxin results in decreased expression of ANLN mRNA

NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538

G

acidic nuclear phosphoprotein 32 family member B

affects expression

T-2 Toxin affects the expression of ANP32B protein

NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717

G

annexin A1

decreases expression

T-2 Toxin results in decreased expression of ANXA1 protein

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A5

affects expression

T-2 Toxin affects the expression of ANXA5 protein

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

apolipoprotein E

increases expression

T-2 Toxin results in increased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

amyloid beta precursor protein

decreases expression

T-2 Toxin results in decreased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

adenine phosphoribosyl transferase

affects expression

T-2 Toxin affects the expression of APRT protein

NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431

G

androgen receptor

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to AR]

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

amphiregulin

multiple interactions

T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

Rho GTPase activating protein 18

decreases expression

T-2 Toxin results in decreased expression of ARHGAP18 mRNA

NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256

G

ADP-ribosylation factor like GTPase 5C

increases expression

T-2 Toxin results in increased expression of ARL5C mRNA

NCBI chr10:82,985,213...82,993,425
Ensembl chr10:82,985,216...82,992,002

G

arrestin, beta 2

increases expression

T-2 Toxin results in increased expression of ARRB2 mRNA

NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850

G

arylsulfatase A

decreases expression

T-2 Toxin results in decreased expression of ARSA mRNA

NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

decreases expression

T-2 Toxin results in decreased expression of ASAP3 mRNA

NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073

G

ankyrin repeat and SOCS box-containing 14

increases expression

T-2 Toxin results in increased expression of ASB14 mRNA

NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135

G

ankyrin repeat and SOCS box-containing 5

increases expression

T-2 Toxin results in increased expression of ASB5 mRNA

NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109

G

ankyrin repeat and SOCS box-containing 6

increases expression

T-2 Toxin results in increased expression of ASB6 mRNA

NCBI chr 3:14,110,628...14,115,274
Ensembl chr 3:14,110,628...14,115,242

G

asparagine synthetase (glutamine-hydrolyzing)

decreases expression

T-2 Toxin results in decreased expression of ASNS mRNA

PMID:31863870 PMID:34581912

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

argininosuccinate synthase 1

decreases expression

T-2 Toxin results in decreased expression of ASS1 mRNA

PMID:31863870 PMID:34581912

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

activating transcription factor 4

multiple interactions
increases expression

salubrinal promotes the reaction [T-2 Toxin results in increased expression of ATF4 protein]

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

autophagy related 12

increases expression

T-2 Toxin results in increased expression of ATG12 protein

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

autophagy related 14

increases expression

T-2 Toxin results in increased expression of ATG14 mRNA

NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113

G

autophagy related 3

increases expression
multiple interactions

T-2 Toxin results in increased expression of ATG3 protein
ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein]
T-2 Toxin results in increased expression of ATG3 mRNA; T-2 Toxin results in increased expression of ATG3 protein

PMID:29870751 PMID:32240701

NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224

G

autophagy related 5

affects expression
increases expression
multiple interactions

T-2 Toxin affects the expression of ATG5 protein
T-2 Toxin results in increased expression of ATG5 protein
3-methyladenine affects the reaction [T-2 Toxin affects the expression of ATG5 protein]

PMID:29413859 PMID:35289972 PMID:36402210

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

decreases expression

T-2 Toxin results in decreased expression of ATIC protein

NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889

G

ATM serine/threonine kinase

increases phosphorylation
decreases expression

T-2 Toxin results in increased phosphorylation of ATM protein
T-2 Toxin results in decreased expression of ATM mRNA

PMID:20150440 PMID:34581912

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATPase phospholipid transporting 11A

decreases expression

T-2 Toxin results in decreased expression of ATP11A mRNA

NCBI chr16:76,657,752...76,767,640
Ensembl chr16:76,657,752...76,767,640

G

ATPase Na+/K+ transporting subunit alpha 1

decreases expression

T-2 Toxin results in decreased expression of ATP1A1 mRNA

NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837

G

ATP synthase F1 subunit alpha

affects expression

T-2 Toxin affects the expression of ATP5F1A protein

NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794

G

ATP synthase F1 subunit beta

affects expression

T-2 Toxin affects the expression of ATP5F1B protein

NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273

G

ATP synthase peripheral stalk subunit d

affects expression

T-2 Toxin affects the expression of ATP5PD protein

NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479

G

ATPase H+ transporting V1 subunit A

affects expression

T-2 Toxin affects the expression of ATP6V1A protein

NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694

G

ATPase H+ transporting V1 subunit B2

affects expression

T-2 Toxin affects the expression of ATP6V1B2 protein

NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745

G

ATPase phospholipid transporting 8B2

decreases expression

T-2 Toxin results in decreased expression of ATP8B2 mRNA

NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:175,378,517...175,401,883

G

AUP1, lipid droplet regulating VLDL assembly factor

increases expression

T-2 Toxin results in increased expression of AUP1 mRNA

NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346

G

Axl receptor tyrosine kinase

increases expression

T-2 Toxin results in increased expression of AXL mRNA

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

beta-2 microglobulin

increases expression

T-2 Toxin results in increased expression of B2M protein

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

G

BAG cochaperone 5

increases expression

T-2 Toxin results in increased expression of BAG5 mRNA

NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970

G

BCL2-antagonist/killer 1

increases expression

T-2 Toxin results in increased expression of BAK1 mRNA

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

G

BCL2 associated X, apoptosis regulator

affects localization
multiple interactions
increases expression
affects expression
decreases expression

T-2 Toxin affects the localization of BAX protein
Selenium inhibits the reaction [T-2 Toxin results in increased expression of BAX mRNA]
T-2 Toxin results in increased expression of BAX mRNA; T-2 Toxin results in increased expression of BAX protein
T-2 Toxin affects the expression of BAX protein
T-2 Toxin results in decreased expression of BAX protein

PMID:16307838 PMID:19524637 PMID:19541794 PMID:21296132 PMID:26138683 More...

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

increases expression

T-2 Toxin results in increased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

branched chain amino acid transaminase 1

decreases expression

T-2 Toxin results in decreased expression of BCAT1 mRNA

NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597

G

BRCA2 and CDKN1A interacting protein

increases expression

T-2 Toxin results in increased expression of BCCIP mRNA

NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:188,512,367...188,524,958

G

BCL2, apoptosis regulator

increases expression
decreases expression
increases activity

T-2 Toxin results in increased expression of BCL2 mRNA; T-2 Toxin results in increased expression of BCL2 protein
T-2 Toxin results in decreased expression of BCL2 mRNA
T-2 Toxin results in decreased expression of BCL2 mRNA; T-2 Toxin results in decreased expression of BCL2 protein
T-2 Toxin results in increased activity of BCL2 protein

PMID:19524637 PMID:21296132 PMID:28697680 PMID:29870751 PMID:33508416 More...

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

decreases expression
affects expression

T-2 Toxin results in decreased expression of BCL2L1 mRNA; T-2 Toxin results in decreased expression of BCL2L1 protein
T-2 Toxin affects the expression of BCL2L1 protein

PMID:29413859 PMID:29432840

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

beclin 1

increases expression
multiple interactions
affects expression

T-2 Toxin results in increased expression of BECN1 mRNA
3-methyladenine inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Selenium deficiency inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Sirolimus promotes the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]
T-2 Toxin results in increased expression of BECN1 protein
T-2 Toxin affects the expression of BECN1 protein
3-methyladenine affects the reaction [T-2 Toxin affects the expression of BECN1 protein]

PMID:30629952 PMID:35289972 PMID:36402210

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

bone gamma-carboxyglutamate protein

decreases expression

T-2 Toxin results in decreased expression of BGLAP protein

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

BH3 interacting domain death agonist

decreases expression

T-2 Toxin results in decreased expression of BID protein

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

BCL2 interacting protein 3 like

increases expression

T-2 Toxin results in increased expression of BNIP3L mRNA

NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803

G

BOP1 ribosomal biogenesis factor

increases expression

T-2 Toxin results in increased expression of BOP1 mRNA

NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931

G

3'(2'), 5'-bisphosphate nucleotidase 1

affects expression

T-2 Toxin affects the expression of BPNT1 protein

NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503

G

BRCA1 interacting helicase 1

decreases expression

T-2 Toxin results in decreased expression of BRIP1 mRNA

NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324

G

BUD23, rRNA methyltransferase and ribosome maturation factor

increases expression

T-2 Toxin results in increased expression of BUD23 mRNA

NCBI chr12:21,629,551...21,640,758
Ensembl chr12:21,629,536...21,640,751

G

complement C5

increases expression

T-2 Toxin results in increased expression of C5 mRNA

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

G

calmodulin 1

affects expression

T-2 Toxin affects the expression of CALM1 protein

NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227

G

calpain, small subunit 1

affects expression

T-2 Toxin affects the expression of CAPNS1 protein

NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795

G

cysteinyl-tRNA synthetase 1

decreases expression

T-2 Toxin results in decreased expression of CARS1 mRNA

PMID:26141394 PMID:34581912

NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941

G

caspase 12

multiple interactions
increases expression

salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA]
salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 protein]
T-2 Toxin results in increased expression of CASP12 mRNA; T-2 Toxin results in increased expression of CASP12 protein

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 3

multiple interactions
increases activity
increases expression
affects expression

3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; Selenium deficiency promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; Sirolimus inhibits the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP3 protein
T-2 Toxin results in increased expression of CASP3 mRNA
T-2 Toxin results in increased expression of CASP3 mRNA; T-2 Toxin results in increased expression of CASP3 protein; T-2 Toxin results in increased expression of CASP3 protein modified form
Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein]; T-2 Toxin results in increased expression of and results in increased activity of CASP3 protein; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein]
T-2 Toxin affects the expression of CASP3 protein

PMID:19428930 PMID:19524637 PMID:19541794 PMID:21295106 PMID:21296132 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 7

increases activity

T-2 Toxin results in increased activity of CASP7 protein

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

increases expression
increases activity
multiple interactions

T-2 Toxin results in increased expression of CASP8 mRNA
T-2 Toxin results in increased activity of CASP8 protein
Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein]

PMID:26141394 PMID:29432840 PMID:29567467 PMID:29870751

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

increases activity
multiple interactions
increases expression

T-2 Toxin results in increased activity of CASP9 protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP9 protein
T-2 Toxin results in increased expression of CASP9 mRNA
Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein]; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein]

PMID:19524637 PMID:21296132 PMID:29432840 PMID:29567467 PMID:33508416 More...

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

increases activity
decreases expression
multiple interactions
decreases activity
increases expression

T-2 Toxin results in increased activity of CAT protein
T-2 Toxin results in decreased expression of CAT mRNA
T-2 Toxin affects the expression of and affects the activity of CAT protein
T-2 Toxin results in decreased activity of CAT protein
T-2 Toxin results in increased expression of CAT mRNA

PMID:19526462 PMID:21112371 PMID:23929680 PMID:27842451 PMID:29432840 More...

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

carbonyl reductase 1

affects expression

T-2 Toxin affects the expression of CBR1 protein

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

coiled-coil domain containing 137

increases expression

T-2 Toxin results in increased expression of CCDC137 mRNA

NCBI chr10:105,730,776...105,737,158
Ensembl chr10:105,730,739...105,737,158

G

coiled-coil domain containing 34

increases expression

T-2 Toxin results in increased expression of CCDC34 mRNA

NCBI chr 3:96,553,074...96,588,310
Ensembl chr 3:96,552,992...96,588,146

G

cellular communication network factor 3

decreases expression

T-2 Toxin results in decreased expression of CCN3 mRNA

NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019

G

cyclin B1 interacting protein 1

increases expression

T-2 Toxin results in increased expression of CCNB1IP1 mRNA

NCBI chr15:24,014,905...24,031,357
Ensembl chr15:24,014,908...24,028,475

G

cyclin B2

decreases expression

T-2 Toxin results in decreased expression of CCNB2 mRNA

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

cyclin D1

decreases expression

T-2 Toxin results in decreased expression of CCND1 mRNA
T-2 Toxin results in decreased expression of CCND1 mRNA; T-2 Toxin results in decreased expression of CCND1 protein

PMID:22454431 PMID:29567467 PMID:35289972

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin G1

decreases expression

T-2 Toxin results in decreased expression of CCNG1 mRNA

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

cyclin G2

decreases expression

T-2 Toxin results in decreased expression of CCNG2 mRNA

NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830

G

chaperonin containing TCP1 subunit 2

decreases expression

T-2 Toxin results in decreased expression of CCT2 protein

NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944

G

CD24 molecule

decreases expression

T-2 Toxin results in decreased expression of CD24 mRNA

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

G

CD274 molecule

increases expression

T-2 Toxin results in increased expression of CD274 protein

NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450

G

CD40 molecule

increases expression

T-2 Toxin results in increased expression of CD40 mRNA

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

G

CD44 molecule

multiple interactions
decreases expression

Selenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein]
T-2 Toxin results in decreased expression of CD44 mRNA; T-2 Toxin results in decreased expression of CD44 protein

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

CD55 molecule (Cromer blood group)

decreases expression

T-2 Toxin results in decreased expression of CD55 mRNA

NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831

G

CDC42 binding protein kinase alpha

decreases expression

T-2 Toxin results in decreased expression of CDC42BPA mRNA

NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732

G

cell division cycle associated 5

increases expression

T-2 Toxin results in increased expression of CDCA5 mRNA

NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023

G

cell division cycle associated 7

increases expression

T-2 Toxin results in increased expression of CDCA7 mRNA

NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353

G

cell division cycle associated 8

increases expression

T-2 Toxin results in increased expression of CDCA8 mRNA

NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629

G

cyclin-dependent kinase 4

decreases expression

T-2 Toxin results in decreased expression of CDK4 mRNA; T-2 Toxin results in decreased expression of CDK4 protein

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 5

increases expression

T-2 Toxin results in increased expression of CDK5 mRNA

NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112

G

CDK5 regulatory subunit associated protein 1

increases expression

T-2 Toxin results in increased expression of CDK5RAP1 mRNA

NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677

G

cyclin-dependent kinase inhibitor 1A

increases expression

T-2 Toxin results in increased expression of CDKN1A mRNA
T-2 Toxin results in increased expression of CDKN1A mRNA; T-2 Toxin results in increased expression of CDKN1A protein

PMID:22454431 PMID:29567467

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 2A

increases expression

T-2 Toxin results in increased expression of CDKN2A mRNA; T-2 Toxin results in increased expression of CDKN2A protein

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 3

increases expression

T-2 Toxin results in increased expression of CDKN3 mRNA

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

centromere protein E

decreases expression

T-2 Toxin results in decreased expression of CENPE mRNA

NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669

G

centromere protein F

decreases expression

T-2 Toxin results in decreased expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

centromere protein J

decreases expression

T-2 Toxin results in decreased expression of CENPJ mRNA

NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791

G

centrosomal protein 135

decreases expression

T-2 Toxin results in decreased expression of CEP135 mRNA

NCBI chr14:31,530,538...31,595,812
Ensembl chr14:31,531,482...31,595,772

G

cilia and flagella associated protein 96

increases expression

T-2 Toxin results in increased expression of CFAP96 mRNA

NCBI chr16:46,291,075...46,315,616
Ensembl chr16:46,291,311...46,315,625

G

cofilin 1

affects expression

T-2 Toxin affects the expression of CFL1 protein

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

G

glycoprotein hormones, alpha polypeptide

multiple interactions

[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]

PMID:25962641 PMID:30951242

NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191

G

cell growth regulator with ring finger domain 1

increases expression

T-2 Toxin results in increased expression of CGRRF1 mRNA

NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037

G

checkpoint kinase 2

multiple interactions
increases activity

2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of CHEK2 protein]

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

chondroitin polymerizing factor

decreases expression

T-2 Toxin results in decreased expression of CHPF mRNA

NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878

G

cholinergic receptor nicotinic alpha 4 subunit

decreases expression

T-2 Toxin results in decreased expression of CHRNA4 mRNA

NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957

G

cholinergic receptor nicotinic beta 2 subunit

decreases expression

T-2 Toxin results in decreased expression of CHRNB2 mRNA

NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619

G

class II, major histocompatibility complex, transactivator

increases expression

T-2 Toxin results in increased expression of CIITA mRNA

NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440

G

citron rho-interacting serine/threonine kinase

decreases expression

T-2 Toxin results in decreased expression of CIT mRNA

NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860

G

creatine kinase B

affects expression

T-2 Toxin affects the expression of CKB protein

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

creatine kinase, mitochondrial 2

decreases expression

T-2 Toxin results in decreased expression of CKMT2 mRNA

NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430

G

claudin 3

multiple interactions
decreases expression

illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN3 mRNA]

NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001

G

claudin 4

multiple interactions
decreases expression

illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN4 mRNA]

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

chloride intracellular channel 1

affects expression

T-2 Toxin affects the expression of CLIC1 protein

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

CLN8, transmembrane ER and ERGIC protein

increases expression

T-2 Toxin results in increased expression of CLN8 mRNA

NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774

G

clusterin

decreases expression
increases expression

T-2 Toxin results in decreased expression of CLU mRNA
T-2 Toxin results in increased expression of CLU mRNA

PMID:31863870 PMID:34581912

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

canopy FGF signaling regulator 2

affects expression

T-2 Toxin affects the expression of CNPY2 protein

NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519

G

ciliary neurotrophic factor

increases expression

T-2 Toxin results in increased expression of CNTF mRNA

NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877

G

cytochrome C oxidase assembly factor 5

multiple interactions
increases expression

GABPA promotes the reaction [T-2 Toxin results in increased expression of COA5 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to COA5]

NCBI chr 9:39,651,459...39,664,870

G

collagen type X alpha 1 chain

decreases expression

T-2 Toxin results in decreased expression of COL10A1 mRNA

NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494

G

collagen type XI alpha 1 chain

decreases expression

T-2 Toxin results in decreased expression of COL11A1 mRNA

NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853

G

collagen type XV alpha 1 chain

decreases expression

T-2 Toxin results in decreased expression of COL15A1 mRNA

NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591

G

collagen type I alpha 1 chain

decreases expression

T-2 Toxin results in decreased expression of COL1A1 mRNA

PMID:22800716 PMID:35289972

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

multiple interactions
decreases expression

3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of COL1A2 protein]

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type II alpha 1 chain

decreases expression

T-2 Toxin results in decreased expression of COL2A1 mRNA

PMID:22800716 PMID:34673134

NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546

G

collagen type IX alpha 1 chain

decreases expression

T-2 Toxin results in decreased expression of COL9A1 mRNA

NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213

G

collagen beta(1-O)galactosyltransferase 2

decreases expression

T-2 Toxin results in decreased expression of COLGALT2 mRNA

NCBI chr13:64,523,641...64,628,295
Ensembl chr13:64,523,658...64,627,549

G

COPI coat complex subunit epsilon

affects expression

T-2 Toxin affects the expression of COPE protein

NCBI chr16:19,114,871...19,125,076
Ensembl chr16:19,114,871...19,128,907

G

COPI coat complex subunit zeta 1

increases expression

T-2 Toxin results in increased expression of COPZ1 mRNA

NCBI chr 7:134,409,523...134,435,661
Ensembl chr 7:134,409,799...134,435,662

G

coenzyme Q5, methyltransferase

increases expression

T-2 Toxin results in increased expression of COQ5 mRNA

NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848

G

coronin 1C

increases expression

T-2 Toxin results in increased expression of CORO1C mRNA

NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179

G

coronin 2B

decreases expression

T-2 Toxin results in decreased expression of CORO2B mRNA

NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302

G

cytochrome c oxidase assembly homolog COX15

increases expression

T-2 Toxin results in increased expression of COX15 mRNA

NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261

G

cytochrome c oxidase assembly factor COX19

increases expression

T-2 Toxin results in increased expression of COX19 mRNA

NCBI chr12:15,303,535...15,313,014
Ensembl chr12:15,303,551...15,313,014

G

cytochrome c oxidase subunit 4i1

multiple interactions
decreases expression

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of COX4I1 protein]

NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921

G

cytochrome c oxidase subunit 6C

affects expression

T-2 Toxin affects the expression of COX6C protein

NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963

G

cytochrome c oxidase subunit VIc, pseudogene

decreases expression

T-2 Toxin results in decreased expression of COX6C-PS1 mRNA

NCBI chr19:52,192,612...52,193,470
Ensembl chr19:52,192,612...52,193,470

G

cAMP responsive element binding protein 1

affects localization
multiple interactions

T-2 Toxin affects the localization of CREB1 protein modified form
T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter]

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cAMP responsive element binding protein 3-like 1

decreases expression

T-2 Toxin results in decreased expression of CREB3L1 mRNA

NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456

G

cAMP responsive element binding protein 5

increases expression

T-2 Toxin results in increased expression of CREB5 mRNA

PMID:31863870 PMID:34581912

NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325

G

cAMP responsive element modulator

decreases expression

T-2 Toxin results in decreased expression of CREM mRNA

NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989

G

CREB regulated transcription coactivator 3

decreases expression

T-2 Toxin results in decreased expression of CRTC3 mRNA

NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500

G

crystallin, alpha B

increases expression

T-2 Toxin results in increased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

citrate synthase

decreases expression

T-2 Toxin results in decreased expression of CS protein

NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421

G

colony stimulating factor 1

increases expression

T-2 Toxin results in increased expression of CSF1 mRNA

PMID:26141394 PMID:34581912

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

cysteine and serine rich nuclear protein 1

increases expression

T-2 Toxin results in increased expression of CSRNP1 mRNA

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

G

cystatin C

increases expression

T-2 Toxin results in increased expression of CST3 protein

NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822

G

cystathionine gamma-lyase

decreases expression

T-2 Toxin results in decreased expression of CTH mRNA

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

catenin beta 1

decreases expression
multiple interactions

T-2 Toxin results in decreased expression of CTNNB1 mRNA; T-2 Toxin results in decreased expression of CTNNB1 protein
3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of CTNNB1 protein]

PMID:35289972 PMID:36402210

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

chymotrypsin-like

affects expression

T-2 Toxin affects the expression of CTRB1 protein

NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626

G

cathepsin A

decreases expression

T-2 Toxin results in decreased expression of CTSA mRNA

NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215

G

CWC27 spliceosome associated cyclophilin

increases expression

T-2 Toxin results in increased expression of CWC27 mRNA

NCBI chr 2:35,764,674...35,975,908
Ensembl chr 2:35,764,686...35,975,872

G

cytochrome b5 reductase 1

decreases expression

T-2 Toxin results in decreased expression of CYB5R1 mRNA

NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458

G

cytochrome c-1

increases expression

T-2 Toxin results in increased expression of CYC1 mRNA

NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479

G

cytochrome c, somatic

affects localization

T-2 Toxin affects the localization of CYCS protein

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytoplasmic FMR1 interacting protein 1

decreases expression

T-2 Toxin results in decreased expression of CYFIP1 mRNA

NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386

G

cytochrome P450, family 11, subfamily a, polypeptide 1

multiple interactions
decreases expression
increases expression

[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA
T-2 Toxin results in decreased expression of CYP11A1 mRNA
T-2 Toxin results in increased expression of CYP11A1 mRNA

PMID:25962641 PMID:26141394 PMID:34581912

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 17, subfamily a, polypeptide 1

multiple interactions

[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases expression
multiple interactions

T-2 Toxin results in decreased expression of CYP19A1 mRNA
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]

PMID:22982764 PMID:30951242

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
increases expression

Dactinomycin inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; Resveratrol inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter]; T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter]
T-2 Toxin results in increased expression of CYP1A1 mRNA; T-2 Toxin results in increased expression of CYP1A1 protein

PMID:21453744 PMID:22982764 PMID:31470059

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytokine like 1

decreases expression

T-2 Toxin results in decreased expression of CYTL1 mRNA

NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886

G

aspartyl-tRNA synthetase 2 (mitochondrial)

decreases expression

T-2 Toxin results in decreased expression of DARS2 mRNA

NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934

G

decapping enzyme, scavenger

increases expression

T-2 Toxin results in increased expression of DCPS mRNA

NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389

G

doublecortin

increases expression

T-2 Toxin results in increased expression of DCX mRNA

NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476

G

dicarbonyl and L-xylulose reductase

increases expression

T-2 Toxin results in increased expression of DCXR mRNA

NCBI chr10:106,006,404...106,008,293

G

damage specific DNA binding protein 2

increases expression

T-2 Toxin results in increased expression of DDB2 mRNA

NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

T-2 Toxin results in increased expression of DDIT3 mRNA; T-2 Toxin results in increased expression of DDIT3 protein
Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein]
salubrinal inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein]

PMID:26141394 PMID:29454614 PMID:34673134

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

decreases expression

T-2 Toxin results in decreased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

DExD-box helicase 52

increases expression

T-2 Toxin results in increased expression of DDX52 mRNA

NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266

G

DEAD-box helicase 55

multiple interactions
increases expression

GABPA promotes the reaction [T-2 Toxin results in increased expression of DDX55 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to DDX55]

NCBI chr12:32,034,462...32,050,218
Ensembl chr12:32,034,462...32,050,219

G

DEAD-box helicase 56

increases expression

T-2 Toxin results in increased expression of DDX56 mRNA

NCBI chr14:81,112,008...81,122,331
Ensembl chr14:81,112,012...81,122,333

G

DNA fragmentation factor subunit alpha

increases expression

T-2 Toxin results in increased expression of DFFA mRNA

NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633

G

DGCR8 microprocessor complex subunit

increases expression

T-2 Toxin results in increased expression of DGCR8 mRNA

NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242

G

24-dehydrocholesterol reductase

decreases expression

T-2 Toxin results in decreased expression of DHCR24 mRNA

PMID:31863870 PMID:34581912

NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137

G

diablo, IAP-binding mitochondrial protein

increases expression

T-2 Toxin results in increased expression of DIABLO protein

NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387

G

DISC1 scaffold protein

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to DISC1]

NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778

G

DnaJ heat shock protein family (Hsp40) member C10

decreases expression

T-2 Toxin results in decreased expression of DNAJC10 mRNA

NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719

G

DnaJ heat shock protein family (Hsp40) member C4

affects expression

T-2 Toxin affects the expression of DNAJC4 protein

NCBI chr 1:204,178,189...204,182,412
Ensembl chr 1:204,178,191...204,182,387

G

deoxyribonuclease 1-like 1

decreases expression

T-2 Toxin results in decreased expression of DNASE1L1 mRNA

NCBI chr X:152,056,942...152,065,518
Ensembl chr X:152,056,942...152,065,518

G

deoxyribonuclease 2, lysosomal

decreases expression

T-2 Toxin results in decreased expression of DNASE2 mRNA

NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376

G

dynamin 1-like

increases expression
multiple interactions

T-2 Toxin results in increased expression of DNM1L mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to DNM1L]

NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482

G

DNA methyltransferase 1

increases expression

T-2 Toxin results in increased expression of DNMT1 mRNA; T-2 Toxin results in increased expression of DNMT1 protein

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

increases expression

T-2 Toxin results in increased expression of DNMT3A mRNA; T-2 Toxin results in increased expression of DNMT3A protein

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

docking protein 3

increases expression

T-2 Toxin results in increased expression of DOK3 mRNA

NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188

G

diphthamide biosynthesis 1

increases expression

T-2 Toxin results in increased expression of DPH1 mRNA

NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850

G

dpy-19 like C-mannosyltransferase 1

decreases expression

T-2 Toxin results in decreased expression of DPY19L1 mRNA

NCBI chr 8:22,933,163...23,021,461
Ensembl chr 8:22,933,163...23,021,751

G

destrin, actin depolymerizing factor

affects expression

T-2 Toxin affects the expression of DSTN protein

NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379

G

dual specificity phosphatase 1

decreases expression
increases expression

T-2 Toxin results in decreased expression of DUSP1 mRNA
T-2 Toxin results in increased expression of DUSP1 mRNA

PMID:26141394 PMID:34581912

NCBI chr10:16,680,478...16,683,275

G

dynein light chain LC8-type 1

increases expression

T-2 Toxin results in increased expression of DYNLL1 mRNA

NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741

G

extracellular matrix protein 2

decreases expression

T-2 Toxin results in decreased expression of ECM2 mRNA

NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516

G

eukaryotic translation elongation factor 1 delta

affects expression

T-2 Toxin affects the expression of EEF1D protein

NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799

G

eukaryotic translation elongation factor 1 gamma

affects expression

T-2 Toxin affects the expression of EEF1G protein

NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382

G

eukaryotic translation elongation factor 2

affects expression

T-2 Toxin affects the expression of EEF2 protein

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

estrogen-induced osteoclastogenesis regulator 1

decreases expression

T-2 Toxin results in decreased expression of EEIG1 mRNA

NCBI chr 3:15,822,441...15,854,651
Ensembl chr 3:15,823,144...15,854,643

G

EF-hand domain family, member D1

decreases expression

T-2 Toxin results in decreased expression of EFHD1 mRNA

NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917

G

epidermal growth factor

decreases expression

T-2 Toxin results in decreased expression of EGF mRNA

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

eukaryotic translation initiation factor 2-alpha kinase 2

increases expression

T-2 Toxin results in increased expression of EIF2AK2 mRNA

NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971

G

eukaryotic translation initiation factor 2 alpha kinase 3

decreases expression
increases phosphorylation

T-2 Toxin results in decreased expression of EIF2AK3 mRNA
T-2 Toxin results in increased phosphorylation of EIF2AK3 protein

PMID:31863870 PMID:34673134

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2 subunit alpha

increases phosphorylation
multiple interactions

T-2 Toxin results in increased phosphorylation of EIF2S1 protein
Selenomethionine inhibits the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein]
salubrinal promotes the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein]

PMID:29454614 PMID:34673134

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 3, subunit D

increases expression

T-2 Toxin results in increased expression of EIF3D mRNA

NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206

G

eukaryotic translation initiation factor 3, subunit G

increases expression

T-2 Toxin results in increased expression of EIF3G mRNA

NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808

G

eukaryotic translation initiation factor 3, subunit I

affects expression

T-2 Toxin affects the expression of EIF3I protein

NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676

G

eukaryotic translation initiation factor 3, subunit J

increases expression

T-2 Toxin results in increased expression of EIF3J mRNA

NCBI chr 3:108,985,103...109,007,341
Ensembl chr 3:108,985,118...109,007,953

G

eukaryotic translation initiation factor 4A2

increases expression

T-2 Toxin results in increased expression of EIF4A2 mRNA

NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781

G

eukaryotic translation initiation factor 5A

affects expression

T-2 Toxin affects the expression of EIF5A protein

NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656

G

eukaryotic translation initiation factor 6

affects expression

T-2 Toxin affects the expression of EIF6 protein

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

elongin C

affects expression

T-2 Toxin affects the expression of ELOC protein

NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890

G

EMG1 N1-specific pseudouridine methyltransferase

increases expression

T-2 Toxin results in increased expression of EMG1 mRNA

NCBI chr 4:157,509,258...157,517,540
Ensembl chr 4:157,509,277...157,517,540

G

enolase 1

affects expression

T-2 Toxin affects the expression of ENO1 protein

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

eomesodermin

increases expression

T-2 Toxin results in increased expression of EOMES mRNA

NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316

G

endothelial PAS domain protein 1

multiple interactions
increases expression

BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 mRNA]; BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 protein]
T-2 Toxin results in increased expression of EPAS1 mRNA; T-2 Toxin results in increased expression of EPAS1 protein

PMID:22800716 PMID:34581912

NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228

G

erythrocyte membrane protein band 4.1-like 2

decreases expression

T-2 Toxin results in decreased expression of EPB41L2 mRNA

NCBI chr 1:19,863,010...20,037,795
Ensembl chr 1:19,863,009...20,037,721

G

erythrocyte membrane protein band 4.2

increases expression

T-2 Toxin results in increased expression of EPB42 mRNA

NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932

G

glutamyl-prolyl-tRNA synthetase 1

decreases expression

T-2 Toxin results in decreased expression of EPRS1 mRNA

NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966

G

epiphycan

decreases expression

T-2 Toxin results in decreased expression of EPYC mRNA

NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135

G

epiregulin

multiple interactions

T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

ERGIC and golgi 2

decreases expression

T-2 Toxin results in decreased expression of ERGIC2 mRNA

NCBI chr 4:181,090,808...181,123,074
Ensembl chr 4:181,090,808...181,123,060

G

endoplasmic reticulum metallopeptidase 1

decreases expression

T-2 Toxin results in decreased expression of ERMP1 mRNA

NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909

G

endoplasmic reticulum to nucleus signaling 1

increases expression
multiple interactions

T-2 Toxin results in increased expression of ERN1 protein
ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein]

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

endoplasmic reticulum to nucleus signaling 2

decreases expression
multiple interactions

T-2 Toxin results in decreased expression of ERN2 protein
ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein]

NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289

G

endoplasmic reticulum oxidoreductase 1 alpha

decreases expression

T-2 Toxin results in decreased expression of ERO1A mRNA

NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478

G

endoplasmic reticulum protein 29

affects expression

T-2 Toxin affects the expression of ERP29 protein

NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376

G

estrogen related receptor, alpha

affects expression

T-2 Toxin affects the expression of ESRRA mRNA

NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268

G

exosome component 2

increases expression

T-2 Toxin results in increased expression of EXOSC2 mRNA

NCBI chr 3:14,962,930...14,973,645
Ensembl chr 3:14,962,917...14,973,575

G

ezrin

affects expression

T-2 Toxin affects the expression of EZR protein

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

G

family with sequence similarity 162, member A

increases expression

T-2 Toxin results in increased expression of FAM162A mRNA

NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239

G

family with sequence similarity 216, member A

increases expression

T-2 Toxin results in increased expression of FAM216A mRNA

NCBI chr12:34,198,526...34,207,673
Ensembl chr12:34,198,526...34,207,665

G

FA complementation group I

increases expression

T-2 Toxin results in increased expression of FANCI mRNA

NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640

G

F-box protein 2

affects expression

T-2 Toxin affects the expression of FBXO2 protein

NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355

G

F-box protein 22

increases expression

T-2 Toxin results in increased expression of FBXO22 mRNA

NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148

G

F-box protein 31

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to FBXO31]

NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010

G

F-box and WD repeat domain containing 4

increases expression

T-2 Toxin results in increased expression of FBXW4 mRNA

NCBI chr 1:244,426,892...244,514,188
Ensembl chr 1:244,426,896...244,514,163

G

Fc gamma receptor 2B

increases expression

T-2 Toxin results in increased expression of FCGR2B mRNA

NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778

G

ferrochelatase

increases expression

T-2 Toxin results in increased expression of FECH mRNA

NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348

G

fibroblast growth factor 4

decreases expression

T-2 Toxin results in decreased expression of FGF4 mRNA

NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466

G

fission, mitochondrial 1

multiple interactions

PINK1 promotes the reaction [T-2 Toxin results in increased expression of FIS1 mRNA]

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

FKBP prolyl isomerase 4

affects expression

T-2 Toxin affects the expression of FKBP4 protein

NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833

G

fibromodulin

decreases expression

T-2 Toxin results in decreased expression of FMOD mRNA

NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133

G

FOS like 2, AP-1 transcription factor subunit

increases expression

T-2 Toxin results in increased expression of FOSL2 mRNA

NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034

G

fascin actin-bundling protein 1

affects expression

T-2 Toxin affects the expression of FSCN1 protein

NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211

G

follicle stimulating hormone subunit beta

decreases expression
multiple interactions

T-2 Toxin results in decreased expression of FSHB protein
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Estradiol]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Progesterone]

PMID:26569305 PMID:30951242

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

far upstream element binding protein 1

affects expression

T-2 Toxin affects the expression of FUBP1 protein

NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602

G

alpha-L-fucosidase 1

decreases expression

T-2 Toxin results in decreased expression of FUCA1 mRNA

NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972

G

glucose-6-phosphate dehydrogenase

affects expression
decreases expression

T-2 Toxin affects the expression of G6PD protein
T-2 Toxin results in decreased expression of G6PD mRNA

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

gamma-aminobutyric acid type B receptor subunit 1

increases expression
decreases expression

T-2 Toxin results in increased expression of GABBR1 mRNA
T-2 Toxin results in decreased expression of GABBR1 mRNA

PMID:26141394 PMID:34581912

NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994

G

GA binding protein transcription factor subunit alpha

increases expression
multiple interactions

T-2 Toxin results in increased expression of GABPA mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of COA5 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of DDX55 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF1 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF4 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS3 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS7 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of PEX5 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFAM mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB1M mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB2M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to AFG1L]; T-2 Toxin promotes the reaction [GABPA protein binds to AR]; T-2 Toxin promotes the reaction [GABPA protein binds to COA5]; T-2 Toxin promotes the reaction [GABPA protein binds to DDX55]; T-2 Toxin promotes the reaction [GABPA protein binds to DISC1]; T-2 Toxin promotes the reaction [GABPA protein binds to DNM1L]; T-2 Toxin promotes the reaction [GABPA protein binds to FBXO31]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA12]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA1]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA9]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF1]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB2]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB3]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB5]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB7]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS3]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS7]; T-2 Toxin promotes the reaction [GABPA protein binds to NSFL1C]; T-2 Toxin promotes the reaction [GABPA protein binds to PARG]; T-2 Toxin promotes the reaction [GABPA protein binds to PEX5]; T-2 Toxin promotes the reaction [GABPA protein binds to TFAM]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB1M]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB2M]; T-2 Toxin promotes the reaction [GABPA protein binds to UQCRFS1]; T-2 Toxin promotes the reaction [GABPA protein binds to YARS2]; T-2 Toxin results in increased expression of and results in increased localization of GABPA protein

PMID:29870751 PMID:36863559

NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605

G

growth arrest and DNA-damage-inducible, gamma

increases expression

T-2 Toxin results in increased expression of GADD45G mRNA

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

GADD45G interacting protein 1

increases expression

T-2 Toxin results in increased expression of GADD45GIP1 mRNA

NCBI chr19:23,320,662...23,323,211
Ensembl chr19:23,320,159...23,323,236

G

galanin and GMAP prepropeptide

increases expression

T-2 Toxin results in increased expression of GAL mRNA

NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959

G

polypeptide N-acetylgalactosaminyltransferase 1

decreases expression

T-2 Toxin results in decreased expression of GALNT1 mRNA

NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245

G

gigaxonin

increases expression

T-2 Toxin results in increased expression of GAN mRNA

NCBI chr19:45,207,783...45,265,066
Ensembl chr19:45,207,184...45,254,107

G

glucosidase II alpha subunit

decreases expression

T-2 Toxin results in decreased expression of GANAB protein

NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695

G

glyceraldehyde-3-phosphate dehydrogenase

affects expression
decreases expression

T-2 Toxin affects the expression of GAPDH protein
T-2 Toxin results in decreased expression of GAPDH mRNA

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

growth arrest specific 6

decreases expression

T-2 Toxin results in decreased expression of GAS6 mRNA

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

G

golgi associated kinase 1B

increases expression

T-2 Toxin results in increased expression of GASK1B mRNA

NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477

G

glutamyl-tRNA amidotransferase subunit B

increases expression

T-2 Toxin results in increased expression of GATB mRNA

NCBI chr 2:170,930,547...171,017,133
Ensembl chr 2:170,930,542...171,016,695

G

glycine amidinotransferase

decreases expression

T-2 Toxin results in decreased expression of GATM mRNA

NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129

G

1,4-alpha-glucan branching enzyme 1

decreases expression

T-2 Toxin results in decreased expression of GBE mRNA

NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210

G

guanylate binding protein 5

increases expression

T-2 Toxin results in increased expression of GBP5 mRNA

NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061

G

glutamate-cysteine ligase, catalytic subunit

decreases expression
increases expression

T-2 Toxin results in decreased expression of GCLC mRNA
T-2 Toxin results in increased expression of GCLC mRNA

PMID:20854872 PMID:33508416

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

decreases expression
increases expression

T-2 Toxin results in decreased expression of GCLM mRNA
T-2 Toxin results in increased expression of GCLM mRNA

PMID:20854872 PMID:33508416

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

growth differentiation factor 15

increases expression

T-2 Toxin results in increased expression of GDF15 mRNA

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

growth differentiation factor 5

increases expression

T-2 Toxin results in increased expression of GDF5 mRNA

NCBI chr 3:144,454,316...144,458,508
Ensembl chr 3:144,454,338...144,458,612

G

glycerophosphodiester phosphodiesterase domain containing 5

decreases expression

T-2 Toxin results in decreased expression of GDPD5 mRNA

NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446

G

glutamine fructose-6-phosphate transaminase 1

decreases expression

T-2 Toxin results in decreased expression of GFPT1 mRNA

NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471

G

growth hormone 1

multiple interactions
decreases expression

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; T-2 Toxin results in decreased expression of and results in decreased secretion of GH1 protein

PMID:26141394 PMID:29079362

NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078

G

growth hormone inducible transmembrane protein

decreases expression

T-2 Toxin results in decreased expression of GHITM mRNA

NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879

G

growth hormone releasing hormone

increases expression

T-2 Toxin results in increased expression of GHRH mRNA

NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889

G

gastric inhibitory polypeptide

multiple interactions
increases expression

T-2 Toxin results in increased expression of and results in increased secretion of GIP protein
T-2 Toxin results in increased expression of GIP protein

PMID:28666375 PMID:29689362

NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503

G

glycosylated lysosomal membrane protein

decreases expression

T-2 Toxin results in decreased expression of GLMP mRNA

NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960

G

gonadotropin releasing hormone 1

decreases expression
increases expression

T-2 Toxin results in decreased expression of GNRH1 mRNA
T-2 Toxin results in increased expression of GNRH1 mRNA

PMID:26569305 PMID:26847343

NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581

G

gonadotropin releasing hormone receptor

increases expression

T-2 Toxin results in increased expression of GNRHR mRNA

NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861

G

glycoprotein VI

increases expression

T-2 Toxin results in increased expression of GP6 mRNA

NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326

G

G patch domain containing 4

increases expression

T-2 Toxin results in increased expression of GPATCH4 mRNA

NCBI chr 2:173,499,700...173,520,346
Ensembl chr 2:173,509,897...173,518,684

G

glypican 4

decreases expression

T-2 Toxin results in decreased expression of GPC4 mRNA

NCBI chr X:131,644,711...131,755,349
Ensembl chr X:131,644,704...131,755,284

G

G protein-coupled receptor 21

decreases expression

T-2 Toxin results in decreased expression of GPR21 mRNA

NCBI chr 3:21,275,289...21,279,008
Ensembl chr 3:21,275,007...21,277,930

G

G protein-coupled receptor 52

decreases expression

T-2 Toxin results in decreased expression of GPR52 mRNA

NCBI chr13:72,800,265...72,804,989
Ensembl chr13:72,800,127...72,806,180

G

G-protein signaling modulator 2

decreases expression

T-2 Toxin results in decreased expression of GPSM2 mRNA

NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154

G

glutamic--pyruvic transaminase

increases activity

T-2 Toxin results in increased activity of GPT protein

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

increases expression
decreases expression
decreases activity

T-2 Toxin results in increased expression of GPX1 mRNA
T-2 Toxin results in decreased expression of GPX1 mRNA
T-2 Toxin results in decreased activity of GPX1 protein

PMID:26141394 PMID:27842451 PMID:29870751 PMID:30091165

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

decreases expression

T-2 Toxin results in decreased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

growth factor receptor bound protein 10

increases expression
decreases expression

T-2 Toxin results in increased expression of GRB10 mRNA
T-2 Toxin results in decreased expression of GRB10 mRNA

PMID:26141394 PMID:34581912

NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806

G

glutamate ionotropic receptor AMPA type subunit 2

decreases expression

T-2 Toxin results in decreased expression of GRIA2 mRNA

NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510

G

glutamate ionotropic receptor NMDA type subunit 2A

increases expression

T-2 Toxin results in increased expression of GRIN2A mRNA

NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637

G

glutamate metabotropic receptor 4

decreases expression

T-2 Toxin results in decreased expression of GRM4 mRNA

NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821

G

granulin precursor

decreases expression

T-2 Toxin results in decreased expression of GRN mRNA

NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775

G

gasdermin A

decreases expression

T-2 Toxin results in decreased expression of GSDMA mRNA

NCBI chr10:83,614,336...83,639,543
Ensembl chr10:83,627,051...83,639,543

G

glycogen synthase kinase 3 beta

decreases expression
increases expression
multiple interactions

T-2 Toxin results in decreased expression of GSK3B mRNA
T-2 Toxin results in increased expression of GSK3B protein
3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of GSK3B protein]

PMID:26141394 PMID:35289972 PMID:36402210

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione-disulfide reductase

decreases expression
affects expression
multiple interactions

T-2 Toxin results in decreased expression of GSR mRNA
T-2 Toxin affects the expression of GSR mRNA
T-2 Toxin affects the expression of and affects the activity of GSR protein

PMID:19526462 PMID:23929680

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

affects expression
increases expression

T-2 Toxin affects the expression of GSS protein
T-2 Toxin results in increased expression of GSS mRNA

PMID:26141394 PMID:34581912

NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase omega 2

increases expression

T-2 Toxin results in increased expression of GSTO2 mRNA

NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866

G

glutathione S-transferase pi 1

affects expression

T-2 Toxin affects the expression of GSTP1 protein

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 2

increases expression

T-2 Toxin results in increased expression of GSTT2 mRNA

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

H1.10 linker histone

increases expression

T-2 Toxin results in increased expression of H1F10 mRNA

NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448

G

H2A.X variant histone

multiple interactions
increases activity

2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of H2AX protein]

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

decreases expression

T-2 Toxin results in decreased expression of H6PD mRNA

NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171

G

hyaluronan and proteoglycan link protein 1

decreases expression

T-2 Toxin results in decreased expression of HAPLN1 mRNA

NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777

G

hyaluronan synthase 2

decreases expression
increases expression

T-2 Toxin results in decreased expression of HAS2 mRNA
T-2 Toxin results in increased expression of HAS2 mRNA

PMID:18196609 PMID:31863870

NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933

G

HBS1-like translational GTPase

increases expression

T-2 Toxin results in increased expression of HBS1L mRNA

NCBI chr 1:16,092,529...16,170,082
Ensembl chr 1:16,092,547...16,170,074

G

hemoglobin subunit zeta

increases expression

T-2 Toxin results in increased expression of HBZ mRNA

NCBI chr10:15,343,821...15,345,301
Ensembl chr10:15,343,831...15,345,312

G

HCK proto-oncogene, Src family tyrosine kinase

increases expression

T-2 Toxin results in increased expression of HCK mRNA

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

G

helicase, POLQ-like

increases expression

T-2 Toxin results in increased expression of HELQ mRNA

NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960

G

HEXIM P-TEFb complex subunit 2

increases expression

T-2 Toxin results in increased expression of HEXIM2 mRNA

NCBI chr10:88,077,870...88,084,776
Ensembl chr10:88,079,014...88,084,775

G

hypoxia inducible factor 1 subunit alpha

increases expression

T-2 Toxin results in increased expression of HIF1A protein

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

homeodomain interacting protein kinase 3

decreases expression

T-2 Toxin results in decreased expression of HIPK3 mRNA

NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759

G

histone cluster 1 H2B family member D

increases expression

T-2 Toxin results in increased expression of H2BC5 mRNA

NCBI chr17:42,792,887...42,793,268

G

high mobility group AT-hook 1

increases expression

T-2 Toxin results in increased expression of HMGA1 mRNA

NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

T-2 Toxin results in decreased expression of HMGCR mRNA

PMID:22982764 PMID:34581912

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

heme oxygenase 1

decreases expression
increases expression

T-2 Toxin results in decreased expression of HMOX1 mRNA; T-2 Toxin results in decreased expression of HMOX1 protein
T-2 Toxin results in increased expression of HMOX1 mRNA

PMID:20854872 PMID:29432840 PMID:33508416

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein A2/B1

affects expression

T-2 Toxin affects the expression of HNRNPA2B1 protein

NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249

G

heterogeneous nuclear ribonucleoprotein A3

affects expression

T-2 Toxin affects the expression of HNRNPA3 protein

NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306

G

heterogeneous nuclear ribonucleoprotein A/B

affects expression

T-2 Toxin affects the expression of HNRNPAB protein

NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344

G

heterogeneous nuclear ribonucleoprotein H1

affects expression

T-2 Toxin affects the expression of HNRNPH1 protein

NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846

G

heterogeneous nuclear ribonucleoprotein K

affects expression

T-2 Toxin affects the expression of HNRNPK protein

NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997

G

haptoglobin

increases expression

T-2 Toxin results in increased expression of HP mRNA

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

heat shock protein 90 alpha family class A member 1

affects expression

T-2 Toxin affects the expression of HSP90AA1 protein

NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268

G

heat shock protein 90 alpha family class B member 1

affects expression
decreases expression

T-2 Toxin affects the expression of HSP90AB1 protein
T-2 Toxin results in decreased expression of HSP90AB1 mRNA

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

G

heat shock protein 90 beta family member 1

affects expression

T-2 Toxin affects the expression of HSP90B1 protein

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 4

affects expression

T-2 Toxin affects the expression of HSPA4 protein

NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001

G

heat shock protein family A (Hsp70) member 5

multiple interactions
affects expression
increases expression

salubrinal inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein]; T-2 Toxin results in increased degradation of and results in decreased expression of HSPA5 protein
T-2 Toxin affects the expression of HSPA5 protein
Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein]
T-2 Toxin results in increased expression of HSPA5 mRNA; T-2 Toxin results in increased expression of HSPA5 protein

PMID:19336499 PMID:26141394 PMID:29454614 PMID:31170431 PMID:34673134

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 8

affects expression

T-2 Toxin affects the expression of HSPA8 protein

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

heat shock protein family A (Hsp70) member 9

affects expression

T-2 Toxin affects the expression of HSPA9 protein

NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292

G

heat shock protein family B (small) member 1

multiple interactions
increases expression

T-2 Toxin results in increased expression of and results in decreased phosphorylation of HSPB1 protein
T-2 Toxin results in increased expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

heat shock protein family D (Hsp60) member 1

affects expression

T-2 Toxin affects the expression of HSPD1 protein

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

G

HtrA serine peptidase 4

decreases expression

T-2 Toxin results in decreased expression of HTRA4 mRNA

NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074

G

HUS1 checkpoint clamp component

increases expression

T-2 Toxin results in increased expression of HUS1 mRNA

NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442

G

hydroxypyruvate isomerase

increases expression

T-2 Toxin results in increased expression of HYI mRNA

NCBI chr 5:131,894,575...131,897,709
Ensembl chr 5:131,894,598...131,897,251

G

inhibitor of DNA binding 2

increases expression

T-2 Toxin results in increased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

isocitrate dehydrogenase (NADP(+)) 1

decreases expression

T-2 Toxin results in decreased expression of IDH1 mRNA

PMID:26141394 PMID:34581912

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

affects expression

T-2 Toxin affects the expression of IDH3A protein

NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

increases expression

T-2 Toxin results in increased expression of IDH3B mRNA

NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982

G

immediate early response 3

increases expression

T-2 Toxin results in increased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

interferon induced transmembrane protein 10

decreases expression

T-2 Toxin results in decreased expression of IFITM10 mRNA

NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:197,507,503...197,525,151

G

interferon gamma

increases expression

T-2 Toxin results in increased expression of IFNG protein

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon-related developmental regulator 1

increases expression

T-2 Toxin results in increased expression of IFRD1 mRNA

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

insulin-like growth factor 2 mRNA binding protein 2

increases expression

T-2 Toxin results in increased expression of IGF2BP2 mRNA

NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377

G

insulin-like growth factor binding protein 4

decreases expression

T-2 Toxin results in decreased expression of IGFBP4 mRNA

NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225

G

insulin-like growth factor binding protein-like 1

increases expression

T-2 Toxin results in increased expression of IGFBPL1 mRNA

NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833

G

IGF-like family receptor 1

increases expression

T-2 Toxin results in increased expression of IGFLR1 mRNA

NCBI chr 1:85,818,428...85,821,032
Ensembl chr 1:85,816,326...85,821,030

G

IKAROS family zinc finger 3

increases expression

T-2 Toxin results in increased expression of IKZF3 mRNA

NCBI chr10:83,460,564...83,553,591
Ensembl chr10:83,465,745...83,553,591

G

interleukin 10

affects expression
decreases expression

T-2 Toxin affects the expression of IL10 mRNA
T-2 Toxin results in decreased expression of IL10 mRNA; T-2 Toxin results in decreased expression of IL10 protein

PMID:22960706 PMID:31170431

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 11

increases expression
multiple interactions
decreases methylation

T-2 Toxin results in increased expression of IL11 mRNA; T-2 Toxin results in increased expression of IL11 protein
Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of IL11 promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL11 mRNA]

PMID:29079362 PMID:31279042

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 1 alpha

increases expression
decreases methylation

T-2 Toxin results in increased expression of IL1A mRNA
T-2 Toxin results in decreased methylation of IL1A promoter

PMID:21112371 PMID:31279042 PMID:36775139

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

multiple interactions
increases expression

4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; SB 203580 inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; Selenium promotes the reaction [T-2 Toxin results in increased expression of IL1B protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]
T-2 Toxin results in increased expression of IL1B mRNA; T-2 Toxin results in increased expression of IL1B protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]

PMID:18196609 PMID:21112371 PMID:21453744 PMID:22454431 PMID:22960706 More...

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

affects secretion
increases expression

T-2 Toxin affects the secretion of IL2 protein
T-2 Toxin results in increased expression of IL2 mRNA

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 20 receptor subunit beta

decreases expression

T-2 Toxin results in decreased expression of IL20RB mRNA

NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942

G

interleukin 22

increases expression

T-2 Toxin results in increased expression of IL22 mRNA

NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186

G

interleukin 4

affects secretion
decreases expression

T-2 Toxin affects the secretion of IL4 protein
T-2 Toxin results in decreased expression of IL4 mRNA

PMID:8560498 PMID:22960706

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 5

affects secretion

T-2 Toxin affects the secretion of IL5 protein

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

multiple interactions
increases expression
affects expression
decreases methylation

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]
T-2 Toxin results in increased expression of IL6 mRNA; T-2 Toxin results in increased expression of IL6 protein
AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 protein]
T-2 Toxin affects the expression of IL6 mRNA
T-2 Toxin results in decreased methylation of IL6 promoter

PMID:21112371 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 More...

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

IMP U3 small nucleolar ribonucleoprotein 4

increases expression

T-2 Toxin results in increased expression of IMP4 mRNA

NCBI chr 9:36,654,127...36,659,265
Ensembl chr 9:36,654,401...36,660,075

G

insulin induced gene 1

decreases expression

T-2 Toxin results in decreased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

interleukin-1 receptor-associated kinase 1

increases expression

T-2 Toxin results in increased expression of IRAK1 mRNA

NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521

G

interleukin-1 receptor-associated kinase 2

increases expression

T-2 Toxin results in increased expression of IRAK2 mRNA

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

G

immunoglobulin superfamily containing leucine-rich repeat

decreases expression

T-2 Toxin results in decreased expression of ISLR mRNA

NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130

G

integrin subunit alpha 10

decreases expression

T-2 Toxin results in decreased expression of ITGA10 mRNA

NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172

G

integrin subunit alpha 11

decreases expression

T-2 Toxin results in decreased expression of ITGA11 mRNA

NCBI chr 8:63,145,998...63,254,714
Ensembl chr 8:63,146,001...63,254,407

G

integrin subunit alpha M

increases expression
multiple interactions

T-2 Toxin results in increased expression of ITGAM protein
Minocycline inhibits the reaction [T-2 Toxin results in increased expression of ITGAM protein]

NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503

G

integrin subunit beta 1

decreases expression

T-2 Toxin results in decreased expression of ITGB1 mRNA

NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195

G

integrin subunit beta 5

decreases expression

T-2 Toxin results in decreased expression of ITGB5 mRNA

NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472

G

integrin subunit beta like 1

decreases expression

T-2 Toxin results in decreased expression of ITGBL1 mRNA

NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733

G

jagged canonical Notch ligand 1

increases expression

T-2 Toxin results in increased expression of JAG1 mRNA

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

jagged canonical Notch ligand 2

increases expression

T-2 Toxin results in increased expression of JAG2 mRNA

NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818

G

Janus kinase 1

increases expression

T-2 Toxin results in increased expression of JAK1 mRNA

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

G

Janus kinase 2

multiple interactions
increases expression
decreases expression

alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA]
T-2 Toxin results in decreased expression of JAK2 mRNA

PMID:22454431 PMID:34581912

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

junctional adhesion molecule 3

decreases expression

T-2 Toxin results in decreased expression of JAM3 mRNA

NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355

G

Jun dimerization protein 2

decreases expression

T-2 Toxin results in decreased expression of JDP2 mRNA

NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

T-2 Toxin results in increased expression of JUN mRNA

PMID:26141394 PMID:34581912

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

potassium voltage-gated channel subfamily C member 3

increases expression

T-2 Toxin results in increased expression of KCNC3 mRNA

NCBI chr 1:95,080,960...95,095,165
Ensembl chr 1:95,080,960...95,095,160

G

potassium calcium-activated channel subfamily M alpha 1

increases expression

T-2 Toxin results in increased expression of KCNMA1 mRNA

NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198

G

KDEL endoplasmic reticulum protein retention receptor 2

decreases expression

T-2 Toxin results in decreased expression of KDELR2 mRNA

NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153

G

KDEL endoplasmic reticulum protein retention receptor 3

decreases expression

T-2 Toxin results in decreased expression of KDELR3 mRNA

NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600

G

lysine demethylase 4D

increases expression

T-2 Toxin results in increased expression of KDM4D mRNA

NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290

G

Kelch-like ECH-associated protein 1

decreases expression

T-2 Toxin results in decreased expression of KEAP1 mRNA; T-2 Toxin results in decreased expression of KEAP1 protein

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

KIAA0232 homolog

decreases expression

T-2 Toxin results in decreased expression of KIAA0232 mRNA

NCBI chr14:74,094,421...74,159,316
Ensembl chr14:74,094,488...74,159,326

G

kinesin family member 16B

decreases expression

T-2 Toxin results in decreased expression of KIF16B mRNA

NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019

G

KIT proto-oncogene receptor tyrosine kinase

increases expression

T-2 Toxin results in increased expression of KIT mRNA

NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652

G

KIT ligand

decreases expression

T-2 Toxin results in decreased expression of KITLG mRNA; T-2 Toxin results in decreased expression of KITLG protein

NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214

G

KLF transcription factor 6

increases expression

T-2 Toxin results in increased expression of KLF6 mRNA

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

keratin 1

decreases expression

T-2 Toxin results in decreased expression of KRT1 mRNA

NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844

G

keratin 8

affects expression
increases expression

T-2 Toxin affects the expression of KRT8 protein
T-2 Toxin results in increased expression of KRT8 mRNA

PMID:26141394 PMID:34581912

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

laminin subunit alpha 5

increases expression

T-2 Toxin results in increased expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

leucyl-tRNA synthetase 1

decreases expression

T-2 Toxin results in decreased expression of LARS1 mRNA

NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931

G

LBH regulator of WNT signaling pathway

increases expression

T-2 Toxin results in increased expression of LBH mRNA

NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079

G

lymphocyte cytosolic protein 2

decreases expression

T-2 Toxin results in decreased expression of LCP2 mRNA

NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559

G

lactate dehydrogenase A

increases expression

T-2 Toxin results in increased expression of LDHA protein

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

galectin 1

affects expression

T-2 Toxin affects the expression of LGALS1 protein

NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345

G

leucine rich repeat containing G protein coupled receptor 5

decreases expression

T-2 Toxin results in decreased expression of LGR5 mRNA

NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446

G

luteinizing hormone subunit beta

decreases expression
increases secretion

T-2 Toxin results in decreased expression of LHB protein
T-2 Toxin results in increased secretion of LHB protein

PMID:26569305 PMID:26847343

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

luteinizing hormone/choriogonadotropin receptor

multiple interactions

1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]

NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521

G

lin-28 homolog A

increases expression

T-2 Toxin results in increased expression of LIN28A mRNA

NCBI chr 5:146,227,119...146,244,122
Ensembl chr 5:146,227,119...146,244,122

G

zinc finger protein 2-like

increases expression

T-2 Toxin results in increased expression of ZNF2 mRNA

NCBI chr 3:114,793,783...114,818,395
Ensembl chr 3:114,809,723...114,818,387
Ensembl chr 3:114,809,723...114,818,387

G

LDL receptor related protein associated protein 1

affects expression
decreases expression

T-2 Toxin affects the expression of LRPAP1 protein
T-2 Toxin results in decreased expression of LRPAP1 mRNA

PMID:26141394 PMID:31863870

NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414

G

latent transforming growth factor beta binding protein 2

decreases expression

T-2 Toxin results in decreased expression of LTBP2 mRNA

NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208

G

lysozyme 2

increases expression

T-2 Toxin results in increased expression of LYZ mRNA

NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106

G

microtubule-actin crosslinking factor 1

decreases expression

T-2 Toxin results in decreased expression of MACF1 mRNA

NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905

G

microtubule-associated protein 1B

decreases expression

T-2 Toxin results in decreased expression of MAP1B mRNA

NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317

G

microtubule-associated protein 1 light chain 3 beta

increases expression
multiple interactions
affects expression

T-2 Toxin results in increased expression of MAP1LC3B mRNA
T-2 Toxin results in increased expression of and results in increased cleavage of MAP1LC3B protein
T-2 Toxin affects the expression of MAP1LC3B protein
3-methyladenine affects the reaction [T-2 Toxin affects the expression of MAP1LC3B protein]

PMID:29413859 PMID:36402210

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

mitogen activated protein kinase 1

increases phosphorylation

T-2 Toxin results in increased phosphorylation of MAPK1 protein

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen-activated protein kinase 8

increases phosphorylation

T-2 Toxin results in increased phosphorylation of MAPK8 protein

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 8 interacting protein 1

increases expression

T-2 Toxin results in increased expression of MAPK8IP1 mRNA

NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884

G

methionyl-tRNA synthetase 2, mitochondrial

decreases expression

T-2 Toxin results in decreased expression of MARS2 mRNA

NCBI chr 9:56,720,408...56,729,991
Ensembl chr 9:56,720,983...56,723,820

G

methionine adenosyltransferase 2A

decreases expression

T-2 Toxin results in decreased expression of MAT2A mRNA

NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493

G

membrane-bound transcription factor peptidase, site 1

decreases expression

T-2 Toxin results in decreased expression of MBTPS1 mRNA

PMID:31863870 PMID:34581912

NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791

G

MCF.2 cell line derived transforming sequence-like

decreases expression

T-2 Toxin results in decreased expression of MCF2L mRNA

NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733

G

minichromosome maintenance complex component 7

affects expression

T-2 Toxin affects the expression of MCM7 protein

NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063

G

malate dehydrogenase 1

affects expression

T-2 Toxin affects the expression of MDH1 protein

NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925

G

MDM2 proto-oncogene

increases expression

T-2 Toxin results in increased expression of MDM2 mRNA

PMID:26141394 PMID:31863870

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

multiple EGF-like-domains 6

decreases expression

T-2 Toxin results in decreased expression of MEGF6 mRNA

NCBI chr 5:164,738,272...164,839,142
Ensembl chr 5:164,738,352...164,839,139

G

melanotransferrin

decreases expression

T-2 Toxin results in decreased expression of MELTF mRNA

NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300

G

mesoderm development LRP chaperone

affects expression

T-2 Toxin affects the expression of MESD protein

NCBI chr 1:137,866,707...137,879,999
Ensembl chr 1:137,874,242...137,879,999

G

meteorin-like, glial cell differentiation regulator

decreases expression

T-2 Toxin results in decreased expression of METRNL mRNA

NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869

G

methyltransferase 9, His-X-His N1(pi)-histidine

decreases expression

T-2 Toxin results in decreased expression of METTL9 mRNA

NCBI chr 1:175,575,805...175,623,065
Ensembl chr 1:175,577,890...175,623,061

G

milk fat globule EGF and factor V/VIII domain containing

decreases expression

T-2 Toxin results in decreased expression of MFGE8 mRNA

NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073

G

mitofusin 1

multiple interactions

PINK1 promotes the reaction [T-2 Toxin results in increased expression of MFN1 mRNA]

NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640

G

microRNA 155

multiple interactions
increases expression

MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]
T-2 Toxin results in increased expression of MIR155 mRNA

NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718

G

MAPK interacting serine/threonine kinase 2

decreases expression

T-2 Toxin results in decreased expression of MKNK2 mRNA

NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827

G

monocyte to macrophage differentiation-associated

decreases expression

T-2 Toxin results in decreased expression of MMD mRNA

NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528

G

matrix metallopeptidase 1

increases expression

T-2 Toxin results in increased expression of MMP1 protein

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

G

matrix metallopeptidase 12

increases expression

T-2 Toxin results in increased expression of MMP12 mRNA

NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611

G

matrix metallopeptidase 13

multiple interactions
increases expression

4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein]
T-2 Toxin results in increased expression of MMP13 mRNA; T-2 Toxin results in increased expression of MMP13 protein
[salubrinal co-treated with T-2 Toxin] results in increased expression of MMP13 mRNA; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein]

PMID:21144892 PMID:22800716 PMID:34673134 PMID:35213812

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

matrix metallopeptidase 2

increases activity
decreases expression

T-2 Toxin results in increased activity of MMP2 protein
T-2 Toxin results in decreased expression of MMP2 mRNA

PMID:21112371 PMID:22960706

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 3

increases expression

T-2 Toxin results in increased expression of MMP3 mRNA

NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961

G

matrix metallopeptidase 9

affects expression
increases activity
multiple interactions
increases expression

T-2 Toxin affects the expression of MMP9 mRNA
T-2 Toxin results in increased activity of MMP9 protein
T-2 Toxin results in increased expression of and results in increased activity of MMP9 protein
T-2 Toxin results in increased expression of MMP9 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]

PMID:21112371 PMID:22800716 PMID:22960706 PMID:29079362

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

mannose-P-dolichol utilization defect 1

increases expression

T-2 Toxin results in increased expression of MPDU1 mRNA

NCBI chr10:54,374,719...54,380,301
Ensembl chr10:54,374,725...54,380,447

G

M-phase phosphoprotein 9

decreases expression

T-2 Toxin results in decreased expression of MPHOSPH9 mRNA

NCBI chr12:32,275,449...32,346,097
Ensembl chr12:32,275,558...32,342,392

G

myeloperoxidase

increases activity

T-2 Toxin results in increased activity of MPO protein

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

mercaptopyruvate sulfurtransferase

affects expression

T-2 Toxin affects the expression of MPST protein

NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141

G

melanocortin 2 receptor accessory protein 2

decreases expression

T-2 Toxin results in decreased expression of MRAP2 mRNA

NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886

G

MRE11 homolog, double strand break repair nuclease

decreases expression

T-2 Toxin results in decreased expression of MRE11A mRNA

NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279

G

mitochondrial ribosomal protein L58

increases expression

T-2 Toxin results in increased expression of MRPL58 mRNA

NCBI chr10:100,646,374...100,652,871
Ensembl chr10:100,646,216...100,652,871

G

mitochondrial ribosomal protein S18C

increases expression

T-2 Toxin results in increased expression of MRPS18C mRNA

NCBI chr14:8,812,301...8,818,538
Ensembl chr14:8,791,330...8,818,516

G

mitochondrial ribosomal protein S22

increases expression

T-2 Toxin results in increased expression of MRPS22 mRNA

NCBI chr 8:99,184,110...99,197,278
Ensembl chr 8:99,184,109...99,197,291

G

membrane spanning 4-domains A3

decreases expression

T-2 Toxin results in decreased expression of MS4A3 mRNA; T-2 Toxin results in decreased expression of MS4A3 protein

NCBI chr 1:208,462,300...208,480,129
Ensembl chr 1:208,462,301...208,480,101

G

methylsterol monooxygenase 1

decreases expression

T-2 Toxin results in decreased expression of MSMO1 mRNA

NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016

G

mitochondrially encoded ATP synthase membrane subunit 6

affects expression

T-2 Toxin affects the expression of ATP6 mRNA

NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599

G

mitochondrially encoded ATP synthase membrane subunit 8

increases expression

T-2 Toxin results in increased expression of ATP8 mRNA

NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961

G

mitochondrially encoded cytochrome c oxidase I

increases expression

T-2 Toxin results in increased expression of COX1 mRNA

NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867

G

mitochondrially encoded cytochrome c oxidase II

increases expression

T-2 Toxin results in increased expression of COX2 mRNA

NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689

G

mitochondrially encoded cytochrome c oxidase III

increases expression

T-2 Toxin results in increased expression of COX3 mRNA

NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382

G

mitochondrially encoded cytochrome b

decreases expression

T-2 Toxin results in decreased expression of CYTB mRNA

NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3

increases expression

T-2 Toxin results in increased expression of ND3 mRNA

NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5

increases expression

T-2 Toxin results in increased expression of ND5 mRNA

NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

increases expression

T-2 Toxin results in increased expression of ND6 mRNA

NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

decreases expression

T-2 Toxin results in decreased expression of MTHFD2 mRNA

PMID:26141394 PMID:31863870

NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608

G

mechanistic target of rapamycin kinase

affects expression

T-2 Toxin affects the expression of MTOR protein

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

G

myotrophin

affects expression

T-2 Toxin affects the expression of MTPN protein

NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724

G

mucin 2, oligomeric mucus/gel-forming

multiple interactions
decreases expression

ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein]

NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756

G

MYC proto-oncogene, bHLH transcription factor

decreases expression

T-2 Toxin results in decreased expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

nanos C2HC-type zinc finger 1

decreases expression

T-2 Toxin results in decreased expression of NANOS1 mRNA

NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730

G

asparaginyl-tRNA synthetase 1

decreases expression

T-2 Toxin results in decreased expression of NARS1 mRNA

NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622

G

NADH:ubiquinone oxidoreductase subunit A1

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA1]

NCBI chr X:116,424,223...116,427,875
Ensembl chr X:116,424,223...116,428,633

G

NADH:ubiquinone oxidoreductase subunit A12

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA12]

NCBI chr 7:28,771,330...28,798,316
Ensembl chr 7:28,771,330...28,798,315

G

Ndufa4, mitochondrial complex associated

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA4]

NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920

G

NADH:ubiquinone oxidoreductase subunit A9

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA9]

NCBI chr 4:159,659,242...159,688,034
Ensembl chr 4:159,659,242...159,688,018

G

NADH:ubiquinone oxidoreductase complex assembly factor 1

increases expression
multiple interactions

T-2 Toxin results in increased expression of NDUFAF1 mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF1 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF1]

PMID:29870751 PMID:36863559

NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212

G

NADH:ubiquinone oxidoreductase complex assembly factor 2

increases expression
multiple interactions

T-2 Toxin results in increased expression of NDUFAF2 mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2]

PMID:29870751 PMID:36863559

NCBI chr 2:39,535,680...39,647,378
Ensembl chr 2:39,535,689...39,647,316

G

NADH:ubiquinone oxidoreductase complex assembly factor 3

increases expression

T-2 Toxin results in increased expression of NDUFAF3 mRNA

NCBI chr 8:109,261,362...109,263,194
Ensembl chr 8:109,261,363...109,263,194

G

NADH:ubiquinone oxidoreductase complex assembly factor 4

increases expression
multiple interactions

T-2 Toxin results in increased expression of NDUFAF4 mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF4 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF4]

PMID:29870751 PMID:36863559

NCBI chr 5:38,605,169...38,610,341
Ensembl chr 5:38,605,153...38,610,336

G

NADH:ubiquinone oxidoreductase subunit B2

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB2]

NCBI chr 4:68,367,526...68,374,609
Ensembl chr15:46,536,062...46,536,851
Ensembl chr 4:46,536,062...46,536,851

G

NADH:ubiquinone oxidoreductase subunit B3

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB3]

NCBI chr 9:60,129,240...60,139,452
Ensembl chr 9:60,129,154...60,139,446

G

NADH:ubiquinone oxidoreductase subunit B4

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4]

NCBI chr11:63,063,723...63,070,426
Ensembl chr11:63,063,795...63,070,425

G

NADH:ubiquinone oxidoreductase subunit B5

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB5]

NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589

G

NADH:ubiquinone oxidoreductase subunit B7

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB7]

NCBI chr19:24,568,241...24,572,579
Ensembl chr19:24,568,241...24,572,579

G

NADH:ubiquinone oxidoreductase core subunit S1

increases expression

T-2 Toxin results in increased expression of NDUFS1 mRNA

NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893

G

NADH:ubiquinone oxidoreductase core subunit S3

affects expression
increases expression
multiple interactions

T-2 Toxin affects the expression of NDUFS3 protein
T-2 Toxin results in increased expression of NDUFS3 mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS3 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS3]

PMID:26141394 PMID:29870751 PMID:36863559

NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824

G

NADH:ubiquinone oxidoreductase subunit S4

increases expression

T-2 Toxin results in increased expression of NDUFS4 mRNA

NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846

G

NADH:ubiquinone oxidoreductase subunit S5

decreases expression

T-2 Toxin results in decreased expression of NDUFS5 mRNA

NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
Ensembl chr14:135,974,034...135,979,603
Ensembl chr 2:135,974,034...135,979,603

G

NADH:ubiquinone oxidoreductase subunit S6

increases expression

T-2 Toxin results in increased expression of NDUFS6 mRNA

NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467

G

NADH:ubiquinone oxidoreductase core subunit S7

increases expression
multiple interactions

T-2 Toxin results in increased expression of NDUFS7 mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS7 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS7]

PMID:29870751 PMID:36863559

NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195

G

NADH:ubiquinone oxidoreductase core subunit S8

increases expression

T-2 Toxin results in increased expression of NDUFS8 mRNA

NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511

G

NADH:ubiquinone oxidoreductase core subunit V1

increases expression

T-2 Toxin results in increased expression of NDUFV1 mRNA

NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466

G

NADH:ubiquinone oxidoreductase core subunit V2

increases expression

T-2 Toxin results in increased expression of NDUFV2 mRNA

NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713

G

NADH:ubiquinone oxidoreductase subunit V3

increases expression

T-2 Toxin results in increased expression of NDUFV3 mRNA

NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074

G

neurofilament heavy chain

increases expression

T-2 Toxin results in increased expression of NEFH mRNA

NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351

G

negative elongation factor complex member E

increases expression

T-2 Toxin results in increased expression of NELFE mRNA

NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355

G

NFE2 like bZIP transcription factor 2

decreases expression
increases expression
multiple interactions

T-2 Toxin results in decreased expression of NFE2L2 mRNA; T-2 Toxin results in decreased expression of NFE2L2 protein
T-2 Toxin results in increased expression of NFE2L2 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein]
T-2 Toxin results in increased expression of NFE2L2 mRNA; T-2 Toxin results in increased expression of NFE2L2 protein
NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM protein]

PMID:20854872 PMID:29432840 PMID:29870751 PMID:33508416 PMID:35842139

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NFKB inhibitor alpha

multiple interactions
increases phosphorylation

BAY 11-7085 inhibits the reaction [T-2 Toxin results in decreased expression of and results in increased degradation of NFKBIA protein]; T-2 Toxin results in increased degradation of and results in decreased expression of NFKBIA protein
T-2 Toxin results in increased phosphorylation of NFKBIA protein

PMID:22800716 PMID:36775139

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor like 1

increases expression

T-2 Toxin results in increased expression of NFKBIL1 mRNA

NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616

G

nuclear factor related to kappa B binding protein

increases expression

T-2 Toxin results in increased expression of NFRKB mRNA

NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359

G

nonhomologous end-joining factor 1

increases expression

T-2 Toxin results in increased expression of NHEJ1 mRNA

NCBI chr 9:76,526,322...76,622,488
Ensembl chr 9:76,526,324...76,622,444

G

niban apoptosis regulator 1

decreases expression

T-2 Toxin results in decreased expression of NIBAN1 mRNA

NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729

G

NME/NM23 nucleoside diphosphate kinase 2

affects expression

T-2 Toxin affects the expression of NME2 protein

NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538

G

nucleolar protein 9

increases expression

T-2 Toxin results in increased expression of NOL9 mRNA

NCBI chr 5:162,546,522...162,566,625
Ensembl chr 5:162,546,541...162,566,191

G

nucleolar and coiled-body phosphoprotein 1

increases expression

T-2 Toxin results in increased expression of NOLC1 mRNA

NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088

G

NOP14 nucleolar protein

increases expression

T-2 Toxin results in increased expression of NOP14 mRNA

NCBI chr14:76,081,313...76,102,454
Ensembl chr14:76,080,793...76,102,453

G

NOP2 nucleolar protein

increases expression

T-2 Toxin results in increased expression of NOP2 mRNA

NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459

G

nitric oxide synthase 2

increases expression

T-2 Toxin results in increased expression of NOS2 mRNA

PMID:21112371 PMID:22960706 PMID:36775139

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

nitric oxide synthase 3

decreases expression

T-2 Toxin results in decreased expression of NOS3 mRNA

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

notch receptor 1

increases expression

T-2 Toxin results in increased expression of NOTCH1 mRNA

NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531

G

nucleophosmin 1

affects expression

T-2 Toxin affects the expression of NPM1 protein

NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645

G

neuronal pentraxin receptor

decreases expression

T-2 Toxin results in decreased expression of NPTXR mRNA

NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802

G

NAD(P)H quinone dehydrogenase 1

decreases expression
increases expression

T-2 Toxin results in decreased expression of NQO1 mRNA
T-2 Toxin results in increased expression of NQO1 mRNA

PMID:20854872 PMID:26141394 PMID:33508416

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

N-ribosyldihydronicotinamide:quinone dehydrogenase 2

increases expression

T-2 Toxin results in increased expression of NQO2 protein

NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320

G

nuclear receptor subfamily 0, group B, member 1

decreases expression

T-2 Toxin results in decreased expression of NR0B1 mRNA

NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011

G

nuclear receptor subfamily 4, group A, member 1

decreases expression

T-2 Toxin results in decreased expression of NR4A1 mRNA

NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297

G

nuclear receptor subfamily 5, group A, member 1

decreases expression

T-2 Toxin results in decreased expression of NR5A1 mRNA

NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328

G

nuclear respiratory factor 1

decreases expression
multiple interactions
affects expression

T-2 Toxin results in decreased expression of NRF1 protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of NRF1 protein]
T-2 Toxin affects the expression of NRF1 mRNA
NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 protein]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter]
T-2 Toxin results in decreased expression of NRF1 mRNA; T-2 Toxin results in decreased expression of NRF1 protein

PMID:27363784 PMID:29870751 PMID:31470059 PMID:35842139

NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328

G

nuclear receptor interacting protein 3

increases expression

T-2 Toxin results in increased expression of NRIP3 mRNA

NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600

G

NSFL1 cofactor

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to NSFL1C]

NCBI chr 3:139,978,306...140,002,876
Ensembl chr 3:139,978,301...140,002,870

G

neurotrophic receptor tyrosine kinase 2

decreases expression

T-2 Toxin results in decreased expression of NTRK2 mRNA

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

G

nucleobindin 1

affects expression

T-2 Toxin affects the expression of NUCB1 protein

NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220

G

nucleobindin 2

decreases expression

T-2 Toxin results in decreased expression of NUCB2 mRNA

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

G

NUF2 component of NDC80 kinetochore complex

decreases expression

T-2 Toxin results in decreased expression of NUF2 mRNA

NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766

G

nucleoporin 43

increases expression

T-2 Toxin results in increased expression of NUP43 mRNA

NCBI chr 1:2,144,427...2,157,887
Ensembl chr 1:2,148,043...2,158,186

G

ornithine aminotransferase

affects expression

T-2 Toxin affects the expression of OAT protein

NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682

G

occludin

multiple interactions
decreases expression

illite inhibits the reaction [T-2 Toxin results in decreased expression of OCLN mRNA]
T-2 Toxin results in decreased expression of OCLN mRNA; T-2 Toxin results in decreased expression of OCLN protein

PMID:27153755 PMID:31170431

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

G

OPA1, mitochondrial dynamin like GTPase

multiple interactions

PINK1 promotes the reaction [T-2 Toxin results in increased expression of OPA1 mRNA]

NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109

G

prolyl 4-hydroxylase subunit beta

affects expression

T-2 Toxin affects the expression of P4HB protein

NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500

G

proliferation-associated 2G4

affects expression

T-2 Toxin affects the expression of PA2G4 protein

NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331

G

platelet-activating factor acetylhydrolase 1b, catalytic subunit 2

increases expression

T-2 Toxin results in increased expression of PAFAH1B2 protein

NCBI chr 8:46,260,069...46,312,073
Ensembl chr 8:46,261,064...46,279,833

G

poly (ADP-ribose) glycohydrolase

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to PARG]

NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273

G

Parkinsonism associated deglycase

affects expression

T-2 Toxin affects the expression of PARK7 protein

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

G

poly (ADP-ribose) polymerase 1

increases expression

T-2 Toxin results in increased expression of PARP1 mRNA; T-2 Toxin results in increased expression of PARP1 protein

PMID:28697680 PMID:29432840

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

paired box 6

increases expression

T-2 Toxin results in increased expression of PAX6 mRNA

NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

decreases expression

T-2 Toxin results in decreased expression of PCK2 mRNA

NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283

G

proliferating cell nuclear antigen

affects expression

T-2 Toxin affects the expression of PCNA protein

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

proprotein convertase subtilisin/kexin type 5

decreases expression

T-2 Toxin results in decreased expression of PCSK5 mRNA

NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600

G

prenylcysteine oxidase 1 like

decreases expression

T-2 Toxin results in decreased expression of PCYOX1L mRNA

NCBI chr18:55,150,637...55,161,334
Ensembl chr18:55,150,650...55,161,327

G

programmed cell death 10

affects expression

T-2 Toxin affects the expression of PDCD10 protein

NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018

G

programmed cell death 4

increases expression
decreases expression

T-2 Toxin results in increased expression of PDCD4 mRNA
T-2 Toxin results in decreased expression of PDCD4 mRNA

PMID:26141394 PMID:34581912

NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275

G

programmed cell death 7

increases expression

T-2 Toxin results in increased expression of PDCD7 mRNA

NCBI chr 8:65,862,606...65,877,333
Ensembl chr 8:65,862,387...65,877,333

G

phosphodiesterase 10A

decreases expression

T-2 Toxin results in decreased expression of PDE10A mRNA

NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563

G

phosphodiesterase 4B

increases expression

T-2 Toxin results in increased expression of PDE4B mRNA

NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696

G

platelet derived growth factor subunit A

increases expression

T-2 Toxin results in increased expression of PDGFA mRNA

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

G

platelet-derived growth factor receptor-like

decreases expression

T-2 Toxin results in decreased expression of PDGFRL mRNA

NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850

G

pyruvate dehydrogenase E1 subunit beta

affects expression

T-2 Toxin affects the expression of PDHB protein

NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500

G

protein disulfide isomerase family A, member 3

affects expression

T-2 Toxin affects the expression of PDIA3 protein

NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236

G

protein disulfide isomerase family A, member 4

decreases expression

T-2 Toxin results in decreased expression of PDIA4 mRNA

NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107

G

PDZ and LIM domain 1

decreases expression

T-2 Toxin results in decreased expression of PDLIM1 mRNA

NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076

G

p53 and DNA damage regulated 1

increases expression

T-2 Toxin results in increased expression of PDRG1 mRNA

NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858
Ensembl chr 3:141,476,501...141,483,858

G

proliferation and apoptosis adaptor protein 15

increases expression

T-2 Toxin results in increased expression of PEA15 mRNA

NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499

G

pescadillo ribosomal biogenesis factor 1

increases expression

T-2 Toxin results in increased expression of PES1 mRNA

NCBI chr14:78,850,754...78,867,134
Ensembl chr14:78,850,709...78,867,134

G

peroxisomal biogenesis factor 5

multiple interactions
increases expression

GABPA promotes the reaction [T-2 Toxin results in increased expression of PEX5 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to PEX5]

NCBI chr 4:157,270,671...157,296,432
Ensembl chr 4:157,270,672...157,296,431

G

profilin 1

affects expression

T-2 Toxin affects the expression of PFN1 protein

NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631

G

phosphoglycerate mutase 1

affects expression

T-2 Toxin affects the expression of PGAM1 protein

NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452

G

phosphoglycerate kinase 1

affects expression

T-2 Toxin affects the expression of PGK1 protein

NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418

G

6-phosphogluconolactonase

affects expression
increases expression

T-2 Toxin affects the expression of PGLS protein
T-2 Toxin results in increased expression of PGLS protein

PMID:26141394 PMID:34581912

NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803

G

progesterone receptor

multiple interactions

T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]

NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344

G

prohibitin 1

affects expression
increases expression

T-2 Toxin affects the expression of PHB1 protein
T-2 Toxin results in increased expression of PHB1 mRNA

PMID:26141394 PMID:31863870

NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042

G

phosphoglycerate dehydrogenase

decreases expression

T-2 Toxin results in decreased expression of PHGDH mRNA

NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944

G

pleckstrin homology-like domain, family A, member 1

increases expression

T-2 Toxin results in increased expression of PHLDA1 mRNA

NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

decreases expression

T-2 Toxin results in decreased expression of PIK3CB mRNA

NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663

G

phosphoinositide-3-kinase regulatory subunit 2

decreases expression

T-2 Toxin results in decreased expression of PIK3R2 mRNA

NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065

G

phosphoinositide-3-kinase regulatory subunit 3

increases expression

T-2 Toxin results in increased expression of PIK3R3 mRNA

NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583

G

PTEN induced kinase 1

multiple interactions
increases expression

N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of PINK1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of FIS1 mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of MFN1 mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of OPA1 mRNA]
T-2 Toxin results in increased expression of PINK1 mRNA; T-2 Toxin results in increased expression of PINK1 protein

PMID:29870751 PMID:36863559

NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635

G

cAMP-dependent protein kinase inhibitor beta

decreases expression

T-2 Toxin results in decreased expression of PKIB mRNA

NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187

G

cAMP-dependent protein kinase inhibitor gamma

affects expression

T-2 Toxin affects the expression of PKIG protein

NCBI chr 3:152,330,477...152,398,085
Ensembl chr 3:152,366,041...152,398,082

G

pyruvate kinase M1/2

affects expression

T-2 Toxin affects the expression of PKM protein

NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599

G

pleckstrin homology domain containing A1

decreases expression

T-2 Toxin results in decreased expression of PLEKHA1 mRNA

NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156

G

plexin A4

decreases expression

T-2 Toxin results in decreased expression of PLXNA4 mRNA

NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206

G

RNA polymerase II, I and III subunit E

increases expression

T-2 Toxin results in increased expression of POLR2E mRNA

NCBI chr 7:9,666,695...9,670,638
Ensembl chr 7:9,666,716...9,670,643

G

RNA polymerase III subunit C

increases expression

T-2 Toxin results in increased expression of POLR3C mRNA

NCBI chr 2:184,246,201...184,262,150
Ensembl chr 2:184,246,204...184,262,208

G

POP4 homolog, ribonuclease P/MRP subunit

increases expression

T-2 Toxin results in increased expression of POP4 mRNA

NCBI chr 1:90,960,026...90,968,360
Ensembl chr 1:90,960,022...90,968,443

G

POU class 1 homeobox 1

increases expression

T-2 Toxin results in increased expression of POU1F1 mRNA

NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801

G

peroxisome proliferator-activated receptor gamma

increases expression

T-2 Toxin results in increased expression of PPARG mRNA

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 alpha

decreases expression
multiple interactions
increases expression

T-2 Toxin results in decreased expression of PPARGC1A protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein]
T-2 Toxin results in increased expression of PPARGC1A mRNA
T-2 Toxin results in decreased expression of PPARGC1A mRNA; T-2 Toxin results in decreased expression of PPARGC1A protein
NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein]

PMID:27363784 PMID:29870751 PMID:35842139

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

G

PPARG coactivator 1 beta

increases expression

T-2 Toxin results in increased expression of PPARGC1B mRNA

NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194

G

phosphopantothenoylcysteine synthetase

increases expression

T-2 Toxin results in increased expression of PPCS mRNA

NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933

G

peptidylprolyl isomerase A

affects expression

T-2 Toxin affects the expression of PPIA protein

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

G

protein phosphatase 1, regulatory subunit 10

increases expression

T-2 Toxin results in increased expression of PPP1R10 mRNA

NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611

G

protein phosphatase 3 catalytic subunit beta

decreases expression

T-2 Toxin results in decreased expression of PPP3CB mRNA

NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981

G

PPARG related coactivator 1

increases expression

T-2 Toxin results in increased expression of PPRC1 mRNA

NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587

G

prolylcarboxypeptidase

decreases expression

T-2 Toxin results in decreased expression of PRCP mRNA

NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530

G

peroxiredoxin 3

affects expression
decreases expression

T-2 Toxin affects the expression of PRDX3 protein
T-2 Toxin results in decreased expression of PRDX3 mRNA; T-2 Toxin results in decreased expression of PRDX3 protein

PMID:26141394 PMID:34581912

NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111

G

peroxiredoxin 4

affects expression

T-2 Toxin affects the expression of PRDX4 protein

NCBI chr X:40,026,762...40,044,066
Ensembl chr X:40,026,651...40,044,066

G

proline and arginine rich end leucine rich repeat protein

decreases expression

T-2 Toxin results in decreased expression of PRELP mRNA

NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270

G

prickle planar cell polarity protein 2

increases expression

T-2 Toxin results in increased expression of PRICKLE2 mRNA

NCBI chr 4:124,869,655...125,214,862
Ensembl chr 4:124,869,552...125,214,824

G

protein kinase C, beta

decreases expression

T-2 Toxin results in decreased expression of PRKCB mRNA

NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536

G

protein kinase C, zeta

decreases expression

T-2 Toxin results in decreased expression of PRKCZ mRNA

NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367

G

parkin RBR E3 ubiquitin protein ligase

increases expression

T-2 Toxin results in increased expression of PRKN mRNA; T-2 Toxin results in increased expression of PRKN protein

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

G

protein arginine methyltransferase 5

increases expression

T-2 Toxin results in increased expression of PRMT5 mRNA

NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296

G

pre-mRNA processing factor 6

increases expression

T-2 Toxin results in increased expression of PRPF6 mRNA

NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991

G

phosphoserine aminotransferase 1

decreases expression

T-2 Toxin results in decreased expression of PSAT1 mRNA

PMID:31863870 PMID:34581912

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

proteasome 20S subunit alpha 4

affects expression

T-2 Toxin affects the expression of PSMA4 protein

NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890

G

proteasome 20S subunit alpha 6

affects expression

T-2 Toxin affects the expression of PSMA6 protein

NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554

G

proteasome 20S subunit beta 3

affects expression

T-2 Toxin affects the expression of PSMB3 protein

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

G

proteasome 20S subunit beta 7

affects expression

T-2 Toxin affects the expression of PSMB7 protein

NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937

G

proteasome 26S subunit, ATPase 2

increases expression

T-2 Toxin results in increased expression of PSMC2 mRNA; T-2 Toxin results in increased expression of PSMC2 protein

NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185

G

proteasome 26S subunit, non-ATPase 9

increases expression

T-2 Toxin results in increased expression of PSMD9 mRNA

NCBI chr12:33,337,182...33,357,468

G

proteasome activator subunit 3

increases expression

T-2 Toxin results in increased expression of PSME3 protein

NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804

G

prostaglandin I2 synthase

decreases expression

T-2 Toxin results in decreased expression of PTGIS mRNA

NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451

G

prostaglandin-endoperoxide synthase 2

increases expression
multiple interactions

T-2 Toxin results in increased expression of PTGS2 mRNA; T-2 Toxin results in increased expression of PTGS2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]

PMID:36115646 PMID:36775139

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine phosphatase, receptor type, C

decreases expression

T-2 Toxin results in decreased expression of PTPRC mRNA

NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692

G

protein tyrosine phosphatase, receptor type, F

increases expression

T-2 Toxin results in increased expression of PTPRF mRNA

NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023

G

paxillin

increases expression

T-2 Toxin results in increased expression of PXN mRNA

NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931

G

peptide YY

increases expression

T-2 Toxin results in increased expression of PYY protein alternative form

NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815

G

quiescin sulfhydryl oxidase 1

decreases expression

T-2 Toxin results in decreased expression of QSOX1 mRNA

NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459

G

quiescin sulfhydryl oxidase 2

decreases expression

T-2 Toxin results in decreased expression of QSOX2 mRNA

NCBI chr 3:9,034,994...9,064,649
Ensembl chr 3:9,034,994...9,064,664

G

RAB20, member RAS oncogene family

increases expression

T-2 Toxin results in increased expression of RAB20 mRNA

NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529

G

RAB25, member RAS oncogene family

increases expression

T-2 Toxin results in increased expression of RAB25 mRNA

NCBI chr 2:174,000,323...174,006,422
Ensembl chr 2:174,000,323...174,006,422

G

RAB27A, member RAS oncogene family

decreases expression

T-2 Toxin results in decreased expression of RAB27A mRNA

NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829

G

receptor activity modifying protein 1

decreases expression

T-2 Toxin results in decreased expression of RAMP1 mRNA

NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151

G

RAN binding protein 1

affects expression

T-2 Toxin affects the expression of RANBP1 protein

NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838

G

RAS protein activator like 3

increases expression

T-2 Toxin results in increased expression of RASAL3 mRNA

NCBI chr 7:11,396,554...11,411,347
Ensembl chr 7:11,396,090...11,411,465

G

ras related dexamethasone induced 1

decreases expression

T-2 Toxin results in decreased expression of RASD1 mRNA

NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186

G

Ras association domain family member 1

increases expression

T-2 Toxin results in increased expression of RASSF1 mRNA

NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164

G

Ras association domain family member 4

decreases expression

T-2 Toxin results in decreased expression of RASSF4 mRNA

NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411

G

RB transcriptional corepressor 1

decreases phosphorylation
decreases expression

T-2 Toxin results in decreased phosphorylation of RB1 protein
T-2 Toxin results in decreased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

ribokinase

increases expression

T-2 Toxin results in increased expression of RBKS mRNA

NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290

G

RNA binding protein, mRNA processing factor 2

decreases expression

T-2 Toxin results in decreased expression of RBPMS2 mRNA

NCBI chr 8:66,153,169...66,184,278
Ensembl chr 8:66,153,593...66,184,268

G

reticulocalbin 1

affects expression

T-2 Toxin affects the expression of RCN1 protein

NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
affects localization
increases expression

T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter]
T-2 Toxin affects the localization of RELA protein modified form
T-2 Toxin results in increased expression of RELA mRNA

PMID:29079362 PMID:34581912

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RELB proto-oncogene, NF-kB subunit

increases expression

T-2 Toxin results in increased expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

reelin

increases expression

T-2 Toxin results in increased expression of RELN mRNA

NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211

G

regulator of G-protein signaling 12

decreases expression

T-2 Toxin results in decreased expression of RGS12 mRNA

NCBI chr14:75,715,925...75,824,012
Ensembl chr14:75,715,934...75,794,596

G

regulator of G-protein signaling 2

increases expression

T-2 Toxin results in increased expression of RGS2 mRNA

NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385

G

regulator of G-protein signaling 4

increases expression

T-2 Toxin results in increased expression of RGS4 mRNA

NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068

G

Ras homolog, mTORC1 binding

increases expression
multiple interactions

T-2 Toxin results in increased expression of RHEB mRNA; T-2 Toxin results in increased expression of RHEB protein
MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]

NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160

G

ras homolog family member B

increases expression

T-2 Toxin results in increased expression of RHOB mRNA

NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108

G

ras homolog family member H

increases expression

T-2 Toxin results in increased expression of RHOH mRNA

NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369

G

RNA 5'-phosphate and 3'-OH ligase 1

increases expression

T-2 Toxin results in increased expression of RLIG1 mRNA

NCBI chr 7:35,396,876...35,408,633
Ensembl chr 7:35,397,995...35,409,600

G

RP9, pre-mRNA splicing factor

increases expression

T-2 Toxin results in increased expression of RP9 mRNA

NCBI chr 8:20,955,447...21,005,225
Ensembl chr 8:20,941,362...21,005,175

G

RNA polymerase II associated protein 1

increases expression

T-2 Toxin results in increased expression of RPAP1 mRNA

NCBI chr 3:106,746,642...106,768,182
Ensembl chr 3:106,656,742...106,768,151

G

ribose 5-phosphate isomerase A

decreases expression

T-2 Toxin results in decreased expression of RPIA mRNA

NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355

G

ribosomal protein lateral stalk subunit P2

affects expression

T-2 Toxin affects the expression of RPLP2 protein

NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645

G

ribophorin II

decreases expression

T-2 Toxin results in decreased expression of RPN2 mRNA

NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543

G

ribonuclease P/MRP subunit p21

increases expression

T-2 Toxin results in increased expression of RPP21 mRNA

NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106

G

ribonuclease P and MRP subunit p25

increases expression

T-2 Toxin results in increased expression of RPP25 mRNA

NCBI chr 8:57,907,352...57,908,732
Ensembl chr 8:57,907,352...57,908,732

G

ribonuclease P/MRP subunit p40

increases expression

T-2 Toxin results in increased expression of RPP40 mRNA

NCBI chr17:28,947,752...28,956,788
Ensembl chr17:28,947,734...28,956,788

G

ribosomal protein S21, pseudogene 1

affects expression

T-2 Toxin affects the expression of RPS21 protein

NCBI chr 5:153,387,133...153,387,476
Ensembl chr 5:153,387,176...153,387,427

G

ribosomal protein S6 kinase A5

decreases expression

T-2 Toxin results in decreased expression of RPS6KA5 mRNA

NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224

G

ribosomal protein SA

affects expression

T-2 Toxin affects the expression of RPSA protein

NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247

G

RUNX family transcription factor 2

decreases expression
multiple interactions

T-2 Toxin results in decreased expression of RUNX2 mRNA; T-2 Toxin results in decreased expression of RUNX2 protein
3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of RUNX2 protein]

PMID:35289972 PMID:36402210

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

G

RuvB-like AAA ATPase 1

increases expression

T-2 Toxin results in increased expression of RUVBL1 mRNA

PMID:31863870 PMID:34581912

NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384

G

RuvB-like AAA ATPase 2

affects expression
increases expression

T-2 Toxin affects the expression of RUVBL2 protein
T-2 Toxin results in increased expression of RUVBL2 mRNA

PMID:26141394 PMID:31863870

NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342

G

scaffold attachment factor B

increases expression

T-2 Toxin results in increased expression of SAFB mRNA

NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644

G

SAP30 binding protein

increases expression

T-2 Toxin results in increased expression of SAP30BP mRNA

NCBI chr10:101,165,777...101,198,503
Ensembl chr10:101,165,856...101,198,502

G

serine carboxypeptidase 1

decreases expression

T-2 Toxin results in decreased expression of SCPEP1 mRNA

NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850

G

succinate dehydrogenase complex flavoprotein subunit A

increases expression

T-2 Toxin results in increased expression of SDHA mRNA

NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535

G

succinate dehydrogenase complex iron sulfur subunit B

increases expression

T-2 Toxin results in increased expression of SDHB mRNA

NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293

G

selenoprotein S

increases expression

T-2 Toxin results in increased expression of SELS mRNA

NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833

G

semaphorin 3F

decreases expression

T-2 Toxin results in decreased expression of SEMA3F mRNA

NCBI chr 8:108,357,629...108,386,569
Ensembl chr 8:108,357,629...108,387,083

G

serine (or cysteine) peptidase inhibitor, clade A, member 3N

decreases expression

T-2 Toxin results in decreased expression of SERPINA3 mRNA

NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433

G

serpin family B member 9

increases expression

T-2 Toxin results in increased expression of SERPINB9 protein

NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230

G

serpin family E member 2

decreases expression

T-2 Toxin results in decreased expression of SERPINE2 mRNA

NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826

G

Set nuclear proto-oncogene

affects expression

T-2 Toxin affects the expression of SET protein

NCBI chr 3:13,334,564...13,345,598
Ensembl chr 3:13,335,041...13,363,567

G

SET domain bifurcated histone lysine methyltransferase 1

increases expression

T-2 Toxin results in increased expression of SETDB1 mRNA

NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506

G

splicing factor 3b, subunit 2

increases expression

T-2 Toxin results in increased expression of SF3B2 mRNA

NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759

G

serum/glucocorticoid regulated kinase 1

increases expression

T-2 Toxin results in increased expression of SGK1 mRNA

NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283

G

sphingomyelin synthase 1

decreases expression

T-2 Toxin results in decreased expression of SGMS1 mRNA

NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603

G

SH3 domain containing GRB2 like 1, endophilin A2

affects expression

T-2 Toxin affects the expression of SH3GL1 protein

NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716

G

S-phase kinase-associated protein 1

affects expression

T-2 Toxin affects the expression of SKP1 protein

NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388

G

solute carrier family 17 member 5

decreases expression

T-2 Toxin results in decreased expression of SLC17A5 mRNA

NCBI chr 8:79,394,416...79,429,387

G

solute carrier family 17 member 6

decreases expression

T-2 Toxin results in decreased expression of SLC17A6 mRNA

NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542

G

solute carrier family 1 member 5

decreases expression

T-2 Toxin results in decreased expression of SLC1A5 mRNA

NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952

G

solute carrier family 27 member 5

increases expression

T-2 Toxin results in increased expression of SLC27A5 mRNA

NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172

G

solute carrier family 29 member 4

decreases expression

T-2 Toxin results in decreased expression of SLC29A4 mRNA

NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834

G

solute carrier family 35, member G1

decreases expression

T-2 Toxin results in decreased expression of SLC35G1 mRNA

NCBI chr 1:236,163,593...236,172,115
Ensembl chr 1:236,163,175...236,170,262

G

solute carrier family 37, member 3

decreases expression

T-2 Toxin results in decreased expression of SLC37A3 mRNA

NCBI chr 4:68,109,314...68,153,590
Ensembl chr 4:68,081,939...68,153,568

G

solute carrier family 38, member 1

decreases expression

T-2 Toxin results in decreased expression of SLC38A1 mRNA

NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218

G

solute carrier family 7 member 2

decreases expression

T-2 Toxin results in decreased expression of SLC7A2 mRNA

NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784

G

slit guidance ligand 1

decreases expression

T-2 Toxin results in decreased expression of SLIT1 mRNA

NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

decreases expression

T-2 Toxin results in decreased expression of SMARCA1 mRNA

NCBI chr X:126,980,201...127,066,385
Ensembl chr X:126,994,947...127,066,347

G

SPARC related modular calcium binding 1

decreases expression

T-2 Toxin results in decreased expression of SMOC1 mRNA

NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699

G

spermine synthase

increases expression

T-2 Toxin results in increased expression of SMS mRNA

NCBI chr X:37,516,949...37,572,657
Ensembl chr X:37,516,931...37,570,822

G

small nuclear ribonucleoprotein polypeptide F

affects expression

T-2 Toxin affects the expression of SNRPF protein

NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129

G

small nuclear ribonucleoprotein 13

increases expression

T-2 Toxin results in increased expression of SNU13 mRNA

NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872
Ensembl chr 1:113,565,295...113,570,872

G

suppressor of cytokine signaling 1

increases expression
multiple interactions

T-2 Toxin results in increased expression of SOCS1 mRNA
MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA]

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

G

superoxide dismutase 1

increases expression
affects expression
decreases activity
decreases expression

T-2 Toxin results in increased expression of SOD1 mRNA
T-2 Toxin affects the expression of SOD1 protein
T-2 Toxin results in decreased activity of SOD1 protein
T-2 Toxin results in decreased expression of SOD1 mRNA

PMID:26138683 PMID:26141394 PMID:27842451 PMID:33508416

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

decreases expression
increases expression

T-2 Toxin results in decreased expression of SOD2 mRNA
T-2 Toxin results in increased expression of SOD2 mRNA

PMID:26141394 PMID:29870751 PMID:30091165

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

Sp1 transcription factor

multiple interactions

T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter]

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

G

Sp7 transcription factor

decreases expression
multiple interactions

T-2 Toxin results in decreased expression of SP7 protein
3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of SP7 protein]

PMID:35289972 PMID:36402210

NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847

G

SPC25 component of NDC80 kinetochore complex

decreases expression

T-2 Toxin results in decreased expression of SPC25 mRNA

NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959

G

signal peptidase complex subunit 3

decreases expression

T-2 Toxin results in decreased expression of SPCS3 mRNA

NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746

G

sphingosine kinase 1

increases expression

T-2 Toxin results in increased expression of SPHK1 mRNA

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

G

Spi-1 proto-oncogene

increases expression

T-2 Toxin results in increased expression of SPI1 mRNA

NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393

G

sequestosome 1

increases expression

T-2 Toxin results in increased expression of SQSTM1 mRNA
T-2 Toxin results in increased expression of SQSTM1 protein

PMID:34581912 PMID:35289972

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

serum response factor binding protein 1

increases expression

T-2 Toxin results in increased expression of SRFBP1 mRNA

NCBI chr18:45,920,389...45,945,385
Ensembl chr18:45,920,446...45,942,515

G

signal sequence receptor subunit 3

decreases expression

T-2 Toxin results in decreased expression of SSR3 mRNA

NCBI chr 2:149,605,005...149,625,069
Ensembl chr 2:149,605,005...149,625,132

G

somatostatin receptor 1

decreases expression

T-2 Toxin results in decreased expression of SSTR1 mRNA

NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802

G

steroidogenic acute regulatory protein

decreases expression
multiple interactions

T-2 Toxin results in decreased expression of STAR mRNA; T-2 Toxin results in decreased expression of STAR protein
[T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]

PMID:25542145 PMID:25962641 PMID:30951242

NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672

G

signal transducer and activator of transcription 1

multiple interactions
increases expression
increases phosphorylation
decreases expression

alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein]
T-2 Toxin results in decreased expression of STAT1 mRNA

PMID:22454431 PMID:26141394

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

signal transducer and activator of transcription 2

increases expression
decreases expression

T-2 Toxin results in increased expression of STAT2 mRNA
T-2 Toxin results in decreased expression of STAT2 mRNA

PMID:22454431 PMID:26141394

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

G

signal transducer and activator of transcription 3

multiple interactions
increases phosphorylation
increases expression
decreases expression

alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]
T-2 Toxin results in decreased expression of STAT3 mRNA

PMID:22454431 PMID:26141394

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

signal transducer and activator of transcription 5B

decreases expression

T-2 Toxin results in decreased expression of STAT5B mRNA

NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668

G

serine/threonine kinase 4

decreases expression

T-2 Toxin results in decreased expression of STK4 mRNA

NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744

G

stomatin like 2

affects expression

T-2 Toxin affects the expression of STOML2 protein

NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920

G

succinate receptor 1

decreases expression

T-2 Toxin results in decreased expression of SUCNR1 mRNA

NCBI chr 2:144,219,066...144,230,568
Ensembl chr 2:144,219,122...144,230,034

G

sulfite oxidase

decreases expression

T-2 Toxin results in decreased expression of SUOX mRNA

NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038

G

syntabulin

increases expression
decreases expression

T-2 Toxin results in increased expression of SYBU mRNA
T-2 Toxin results in decreased expression of SYBU mRNA

PMID:26141394 PMID:31863870

NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828

G

synaptotagmin 11

decreases expression

T-2 Toxin results in decreased expression of SYT11 mRNA

NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964

G

synaptotagmin 17

decreases expression

T-2 Toxin results in decreased expression of SYT17 mRNA

NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960

G

tachykinin, precursor 1

increases expression

T-2 Toxin results in increased expression of TAC1 protein

NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178

G

transaldolase 1

affects expression

T-2 Toxin affects the expression of TALDO1 protein

NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974

G

TatD DNase domain containing 1

increases expression

T-2 Toxin results in increased expression of TATDN1 mRNA

NCBI chr 7:90,449,979...90,481,000
Ensembl chr 7:90,441,079...90,481,133

G

thromboxane A2 receptor

increases expression
decreases expression

T-2 Toxin results in increased expression of TBXA2R mRNA
T-2 Toxin results in decreased expression of TBXA2R mRNA

PMID:26141394 PMID:34581912

NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176

G

t-complex 1

affects expression
increases expression

T-2 Toxin affects the expression of TCP1 protein
T-2 Toxin results in increased expression of TCP1 protein

PMID:26141394 PMID:34581912

NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839

G

telomerase RNA component

decreases expression

T-2 Toxin results in decreased expression of TERC mRNA

NCBI chr 2:112,815,654...112,816,041

G

transferrin

decreases expression

T-2 Toxin results in decreased expression of TF mRNA

NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511

G

transcription factor A, mitochondrial

multiple interactions
decreases expression
increases expression

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of TFAM protein]
T-2 Toxin results in increased expression of TFAM mRNA
NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM protein]
T-2 Toxin results in decreased expression of TFAM mRNA; T-2 Toxin results in decreased expression of TFAM protein
GABPA promotes the reaction [T-2 Toxin results in increased expression of TFAM mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFAM]

PMID:27363784 PMID:29870751 PMID:35842139 PMID:36863559

NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292

G

transcription factor B1, mitochondrial

affects expression
multiple interactions
increases expression

T-2 Toxin affects the expression of TFB1M mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB1M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB1M]

PMID:29870751 PMID:36863559

NCBI chr 1:44,115,240...44,161,737
Ensembl chr 1:44,119,166...44,161,709

G

transcription factor B2, mitochondrial

affects expression
multiple interactions
increases expression

T-2 Toxin affects the expression of TFB2M mRNA
GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB2M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB2M]

PMID:29870751 PMID:36863559

NCBI chr13:91,278,889...91,296,709
Ensembl chr13:91,278,898...91,296,657

G

transcription factor binding to IGHM enhancer 3

increases expression

T-2 Toxin results in increased expression of TFE3 mRNA

NCBI chr X:14,729,547...14,742,830
Ensembl chr X:14,729,550...14,742,571

G

transforming growth factor, beta receptor 1

increases expression

T-2 Toxin results in increased expression of TGFBR1 protein

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

G

transforming growth factor, beta receptor 2

increases expression

T-2 Toxin results in increased expression of TGFBR2 protein

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

G

transforming growth factor beta receptor 3

increases expression

T-2 Toxin results in increased expression of TGFBR3 mRNA

NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341

G

transglutaminase 2

decreases expression

T-2 Toxin results in decreased expression of TGM2 mRNA

NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981

G

thrombospondin 1

decreases expression
increases expression

T-2 Toxin results in decreased expression of THBS1 mRNA
T-2 Toxin results in increased expression of THBS1 mRNA

PMID:31863870 PMID:34581912

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

thrombospondin 2

decreases expression

T-2 Toxin results in decreased expression of THBS2 mRNA

NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789

G

thrombospondin 3

decreases expression

T-2 Toxin results in decreased expression of THBS3 mRNA

NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:174,621,812...174,633,594

G

thyroid hormone receptor beta

multiple interactions

T-2 Toxin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]

NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916

G

translocase of inner mitochondrial membrane 50

increases expression

T-2 Toxin results in increased expression of TIMM50 mRNA

NCBI chr 1:83,574,872...83,582,748
Ensembl chr 1:83,556,757...83,582,793

G

TIMP metallopeptidase inhibitor 1

decreases expression
multiple interactions
affects expression

T-2 Toxin results in decreased expression of TIMP1 protein
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein]
T-2 Toxin affects the expression of TIMP1 mRNA

PMID:21112371 PMID:21144892

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

TIMP metallopeptidase inhibitor 2

decreases expression
multiple interactions
affects expression

T-2 Toxin results in decreased expression of TIMP2 protein
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP2 protein]
T-2 Toxin affects the expression of TIMP2 mRNA

PMID:21112371 PMID:21144892

NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611

G

TIMP metallopeptidase inhibitor 3

decreases expression

T-2 Toxin results in decreased expression of TIMP3 mRNA

NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839

G

transketolase

affects expression

T-2 Toxin affects the expression of TKT protein

NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698

G

transmembrane protein 102

decreases expression

T-2 Toxin results in decreased expression of TMEM102 mRNA

NCBI chr10:54,523,901...54,525,997
Ensembl chr10:54,523,585...54,525,990

G

transmembrane protein 123

decreases expression

T-2 Toxin results in decreased expression of TMEM123 mRNA

NCBI chr 8:4,922,077...4,952,228
Ensembl chr 8:4,922,098...4,952,224

G

transmembrane protein 167A

decreases expression

T-2 Toxin results in decreased expression of TMEM167A mRNA

NCBI chr 2:21,197,799...21,216,746
Ensembl chr 2:21,197,786...21,212,099

G

transmembrane protein 25

decreases expression

T-2 Toxin results in decreased expression of TMEM25 mRNA

NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:45,107,121...45,116,389

G

transmembrane protein 50B

decreases expression

T-2 Toxin results in decreased expression of TMEM50B mRNA

NCBI chr11:30,804,835...30,837,675
Ensembl chr11:30,804,837...30,837,661

G

tumor necrosis factor

multiple interactions
increases expression
decreases methylation

Selenium promotes the reaction [T-2 Toxin results in increased expression of TNF protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]
T-2 Toxin results in increased expression of TNF mRNA; T-2 Toxin results in increased expression of TNF protein
Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of TNF promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]

PMID:18196609 PMID:21112371 PMID:22454431 PMID:22960706 PMID:29079362 More...

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 12A

increases expression

T-2 Toxin results in increased expression of TNFRSF12A mRNA

PMID:26141394 PMID:34581912

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

G

TNF receptor superfamily member 21

increases expression

T-2 Toxin results in increased expression of TNFRSF21 mRNA

NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085

G

translocase of outer mitochondrial membrane 34

increases expression

T-2 Toxin results in increased expression of TOMM34 mRNA

NCBI chr 3:152,729,345...152,746,295
Ensembl chr 3:152,729,349...152,746,373

G

DNA topoisomerase II alpha

decreases expression

T-2 Toxin results in decreased expression of TOP2A mRNA

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

tumor protein p53

increases expression
decreases expression

T-2 Toxin results in increased expression of TP53 mRNA; T-2 Toxin results in increased expression of TP53 protein
T-2 Toxin results in increased expression of TRP53 mRNA; T-2 Toxin results in increased expression of TRP53 protein
T-2 Toxin results in decreased expression of TP53 mRNA

PMID:19524637 PMID:21296132 PMID:29432840 PMID:29567467 PMID:29870751 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

triosephosphate isomerase 1

affects expression

T-2 Toxin affects the expression of TPI1 protein

NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541

G

tripeptidyl peptidase 1

decreases expression

T-2 Toxin results in decreased expression of TPP1 mRNA

NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129

G

translocated promoter region, nuclear basket protein

decreases expression

T-2 Toxin results in decreased expression of TPR mRNA

NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496

G

Tnf receptor-associated factor 2

increases expression

T-2 Toxin results in increased expression of TRAF2 mRNA

NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538

G

TNF receptor-associated protein 1

affects expression

T-2 Toxin affects the expression of TRAP1 protein

NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981

G

tribbles pseudokinase 2

decreases expression

T-2 Toxin results in decreased expression of TRIB2 mRNA

NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370

G

tribbles pseudokinase 3

decreases expression

T-2 Toxin results in decreased expression of TRIB3 mRNA

PMID:31863870 PMID:34581912

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

tRNA methyltransferase 1

increases expression

T-2 Toxin results in increased expression of TRMT1 mRNA

NCBI chr19:23,456,756...23,471,581
Ensembl chr19:23,456,756...23,466,956

G

tRNA mitochondrial 2-thiouridylase

increases expression

T-2 Toxin results in increased expression of TRMU mRNA

NCBI chr 7:116,969,750...116,987,704
Ensembl chr 7:116,969,756...116,986,355

G

TSC22 domain family, member 1

increases expression

T-2 Toxin results in increased expression of TSC22D1 mRNA

NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958

G

tetraspanin 8

decreases expression

T-2 Toxin results in decreased expression of TSPAN8 mRNA

NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356

G

TSR2, ribosome maturation factor

increases expression

T-2 Toxin results in increased expression of TSR2 mRNA

NCBI chr X:20,064,102...20,072,673
Ensembl chr X:20,064,103...20,072,620

G

tetratricopeptide repeat domain 7A

increases expression

T-2 Toxin results in increased expression of TTC7A mRNA

NCBI chr 6:7,159,285...7,261,826
Ensembl chr 6:7,159,061...7,261,892

G

Ttk protein kinase

decreases expression

T-2 Toxin results in decreased expression of TTK mRNA

NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651

G

titin

decreases expression

T-2 Toxin results in decreased expression of TTN mRNA

NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741

G

transthyretin

multiple interactions

T-2 Toxin inhibits the reaction [Thyroxine binds to TTR protein]

NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008

G

tubulin, alpha 1C

affects expression

T-2 Toxin affects the expression of TUBA1C protein

NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr X:130,192,016...130,199,647

G

tubulin, beta 5 class I

affects expression

T-2 Toxin affects the expression of TUBB protein

NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940

G

tubulin, epsilon 1

decreases expression

T-2 Toxin results in decreased expression of TUBE1 mRNA

NCBI chr20:42,552,390...42,570,324
Ensembl chr20:42,552,437...42,570,314

G

Tu translation elongation factor, mitochondrial

affects expression

T-2 Toxin affects the expression of TUFM protein

NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395

G

thioredoxin-like 4B

increases expression

T-2 Toxin results in increased expression of TXNL4B mRNA

NCBI chr19:37,530,157...37,539,827
Ensembl chr19:37,530,152...37,538,521

G

ubiquitin-conjugating enzyme E2N

affects expression

T-2 Toxin affects the expression of UBE2N protein

NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355

G

ubiquitin C-terminal hydrolase L1

affects expression

T-2 Toxin affects the expression of UCHL1 protein

NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590

G

uncoupling protein 1

increases expression

T-2 Toxin results in increased expression of UCP1 mRNA

NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852

G

uncoupling protein 2

increases expression

T-2 Toxin results in increased expression of UCP2 mRNA

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

G

uncoupling protein 3

increases expression

T-2 Toxin results in increased expression of UCP3 mRNA

NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762

G

UPF3A, regulator of nonsense mediated mRNA decay

increases expression

T-2 Toxin results in increased expression of UPF3A mRNA

NCBI chr16:75,757,442...75,768,478
Ensembl chr16:75,757,441...75,769,345

G

ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

increases expression
multiple interactions

T-2 Toxin results in increased expression of UQCRFS1 mRNA
T-2 Toxin promotes the reaction [GABPA protein binds to UQCRFS1]

PMID:29870751 PMID:36863559

NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479

G

UTP14A small subunit processome component

increases expression

T-2 Toxin results in increased expression of UTP14A mRNA

NCBI chr X:127,439,282...127,464,634
Ensembl chr X:127,439,268...127,464,633

G

vesicle amine transport 1

increases expression

T-2 Toxin results in increased expression of VAT1 protein

NCBI chr10:86,389,549...86,397,167
Ensembl chr10:86,389,545...86,397,224

G

voltage-dependent anion channel 1

affects expression

T-2 Toxin affects the expression of VDAC1 protein

NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640

G

voltage-dependent anion channel 2

increases expression

T-2 Toxin results in increased expression of VDAC2 protein

NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553

G

vascular endothelial growth factor A

increases expression

T-2 Toxin results in increased expression of VEGFA protein

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

ventricular zone expressed PH domain-containing 1

increases expression

T-2 Toxin results in increased expression of VEPH1 mRNA

NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266

G

vesicle transport through interaction with t-SNAREs 1A

increases expression

T-2 Toxin results in increased expression of VTI1A mRNA

NCBI chr 1:254,356,343...254,661,854
Ensembl chr 1:254,356,429...254,661,852

G

tryptophanyl-tRNA synthetase 1

decreases expression

T-2 Toxin results in decreased expression of WARS1 mRNA

PMID:31863870 PMID:34581912

NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269

G

WD repeat domain 54

increases expression

T-2 Toxin results in increased expression of WDR54 mRNA

NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:115,654,968...115,661,562

G

WD repeat domain 74

increases expression

T-2 Toxin results in increased expression of WDR74 mRNA

NCBI chr 1:205,631,769...205,636,558
Ensembl chr 1:205,631,824...205,636,563

G

WD repeat domain, phosphoinositide interacting 1

decreases expression

T-2 Toxin results in decreased expression of WIPI1 mRNA

NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846

G

Wnt family member 3A

decreases expression
multiple interactions

T-2 Toxin results in decreased expression of WNT3A protein
3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of WNT3A protein]

PMID:35289972 PMID:36402210

NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324

G

X-box binding protein 1

increases expression
decreases expression

T-2 Toxin results in increased expression of XBP1 protein alternative form
T-2 Toxin results in decreased expression of XBP1 mRNA

PMID:31170431 PMID:31863870

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

G

tyrosyl-tRNA synthetase 2

multiple interactions

T-2 Toxin promotes the reaction [GABPA protein binds to YARS2]

NCBI chr11:84,632,350...84,638,138
Ensembl chr11:84,624,369...84,638,125

G

Y box binding protein 1

increases expression

T-2 Toxin results in increased expression of YBX1 protein

NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

affects expression

T-2 Toxin affects the expression of YWHAB protein

NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

affects expression

T-2 Toxin affects the expression of YWHAE protein

NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

affects expression

T-2 Toxin affects the expression of YWHAG protein

NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

affects expression

T-2 Toxin affects the expression of YWHAQ protein

NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273

G

zinc finger and BTB domain containing 21

increases expression

T-2 Toxin results in increased expression of ZBTB21 mRNA

NCBI chr11:37,312,337...37,327,040
Ensembl chr11:37,312,378...37,326,996

G

zinc finger and BTB domain containing 40

increases expression

T-2 Toxin results in increased expression of ZBTB40 mRNA

NCBI chr 5:149,216,496...149,283,746
Ensembl chr 5:149,219,677...149,254,415

G

zinc finger CCCH type containing 8

increases expression

T-2 Toxin results in increased expression of ZC3H8 mRNA

NCBI chr 3:116,176,779...116,193,752
Ensembl chr 3:116,176,798...116,193,787

G

zinc finger protein 346

increases expression

T-2 Toxin results in increased expression of ZNF346 mRNA

NCBI chr17:9,493,787...9,523,681
Ensembl chr17:9,493,803...9,523,635

G

zinc finger protein 382

increases expression

T-2 Toxin results in increased expression of ZNF382 mRNA

NCBI chr 1:85,377,614...85,400,832
Ensembl chr 1:85,377,484...85,399,667

G

zinc finger protein 422

increases expression

T-2 Toxin results in increased expression of ZNF22 mRNA

NCBI chr 4:149,885,805...149,893,287
Ensembl chr 4:149,885,600...149,893,257

G

zinc finger protein 623

increases expression

T-2 Toxin results in increased expression of ZNF623 mRNA

NCBI chr 7:107,627,334...107,636,254
Ensembl chr 7:107,627,267...107,636,321

verrucarin A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

interleukin 2

increases expression
affects secretion

muconomycin A results in increased expression of IL2 mRNA
muconomycin A affects the secretion of IL2 protein

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 4

affects secretion
increases expression

muconomycin A affects the secretion of IL4 protein
muconomycin A results in increased expression of IL4 mRNA

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 5

affects secretion

muconomycin A affects the secretion of IL5 protein

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

increases expression

muconomycin A results in increased expression of IL6 mRNA

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19808
role	19784
biological role	19782
poison	18590
toxin	15966
mycotoxin	12009
trichothecene	1525
(1S,2S,12S)-3,11-dihydroxy-1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one	0
(2'E)-Roridin L-2	0
(3alpha)-3-Hydroxy-12,13-epoxytrichothec-9-ene-4,8,15-triyl triacetate	0
(S)-7-hydroxytrichothecolone acetate	0
12'-Hydroxyroridin E	0
13'-Acetyltrichoverrin B	0
14'-hydroxymytoxin B	0
14′-dehydrovertisporin	0
15-Acetoxyscirpene-3,4-diol 4-O-a-D-glucopyranoside	0
15-Acetoxyscirpenol	0
15-Acetyl-4-deoxynivalenol	0
15-Deacetylneosolaniol	0
15-acetyldeoxynivalenol	93
15-acetyltrichoverrol B	0
16-hydroxymytoxin B	0
16-hydroxyroridin E	0
2′,3′-deoxyroritoxin D	0
3'-Hydroxy-HT2 toxin	0
3'-Hydroxy-T2 Toxin	0
3'-Hydroxy-T2-triol	0
3,4,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate	0
3,7,8,15-Scirpenetetrol	0
3,8,15-Trihydroxy-12,13-epoxytrichothec-9-en-4-yl acetate	0
3-Acetoxyscirpene-4,15-diol	0
3-Hydroxyroridin E	0
3-acetyldeoxynivalenol	33
3′-epi-16-hydroxyverrucarin A	0
3′-epiverrucarin X	0
4,8-Diacetyl-T2-tetrol	0
4-((Z)-but-2-enoyloxy)-12,13-epoxy-16-hydroxytrichothec-9-ene	0
4-Acetoxyscirpene-3,15-diol	0
4-Deacetylneosolaniol	0
4-Propanoyl-HT2 toxin	0
6'-dehydroxytrichoverrin B	0
6′,12′-epoxymyrotoxin A	0
7'-hydroxymytoxin B	0
7-Hydroxytrichodermol	0
7alpha,8alpha-Dihydroxycalonectrin	0
7beta,8,beta2,'3'-diepoxyroridin H	0
7beta,8beta-epoxyisororidin E	0
7beta,8beta-epoxyroridin H	0
8-Acetoxyroridin E	0
8-Acetoxyroridin H	0
8-Acetyl-T2 tetrol	0
8-Butanoylneosolaniol	0
8-Hexanoylneosolaniol	0
8-Isobutanoylneosolaniol	0
8-Oxodiacetoxyscirpenol	0
8-Pentanoylneosolaniol	0
8-Propanoylneosolaniol	0
8-acetoxy T-2 tetraol	0
8-acetylneosolaniol	0
8-n-Hexanoylneosolaniol	0
8-n-Pentanoylneosolaniol	0
8a-Hydroxyisotrichoverrin A	0
9beta,10beta-Epoxyisotrichoverrin A	0
Acetyl-T2 Toxin	0
Acetyldeoxynivalenol	0
Acetyltrichothecolone	0
Anguidine	0
Anguidol	0
Chartarene D	0
Crotocin	0
DON-10-S-cysteine	0
DON-10-gamma-glutamylcysteine	0
DON-10-glutathione	0
DON-10-isoleucine	0
DON-10-leucine	0
DON-10-phenylalanine	0
DON-10-tyrosine	0
DON-13-S-cysteine	0
DON-15-penicillin G	0
DON-15-sulfate	0
DON-3-sulfate	0
DON-sulfonate 1	0
DON-sulfonate 2	0
DON-sulfonate 3	0
Deoxynivalenol 3-glucoside	2
Diacetoxyscirpenol	21
Epiroridin acid	0
Fusarenone X	42
HT-2 toxin +	800
Harzianum A	0
Isororidin E	0
Isororidin P	0
LSM-36622	0
Monoacetoxyscirpenol	0
Myotoxin A	0
Myrotoxin A	0
Myrotoxin B	0
NX-2	0
NX-3	0
NX-4	0
Neosolaniol	2
Nivalenol	58
Pentahydroxyscirpene	0
Roridin A	12
Roridin E	0
Roridin E acetate	0
Roridin F	0
Roridin H	0
Roridin J	0
Roridin K acetate	0
Roridin L	0
Roridin M	0
Roridin P	0
Roridin Q	0
Roridin R	0
Roridoxin A	0
Roridoxin B	0
Roridoxin C	0
Roritoxin A	0
Roritoxin B	0
Roritoxin C	0
Roritoxin D	0
Satratoxin H	3
Satratoxin H 12',13'-diacetate	0
Satratoxin H 12'-acetate	0
Satratoxin H 13'-acetate	0
Satratoxin I	0
Sporotrichiol	0
Stachybotrichodermone A	0
Standard Solution Nivalenol	0
T-2 Tetraol	0
T-2 toxin	798
T2 Toxin Triol	0
T2 Triol	0
Toxin T2 tetrol	0
Trichobreol A	0
Trichobreol B	0
Trichobreol C	0
Trichodermadiene	0
Trichodermadienediol A	0
Trichodermadienediol B	0
Trichodermarin C	0
Trichodermarin D	0
Trichodermarin E	0
Trichothecinol A	0
Trichothecinol B	0
Trichothecinol C	0
Trichoverrin A	0
Trichoverrin B	0
Trichoverrin C	0
Trichoverritone	0
Trichoverrol A	0
Trichoverrol B	0
Verrol	0
Verrol 4-acetate	0
Verrucarin L	0
Verrucarin L acetate	0
Verrucarin M	0
Verrucarin X	0
Verrucarin Y	0
Verrucarin Z	0
Verrucarin j	0
Verrucarol	0
YM-47524	0
YM-47525	0
[(1R,2R,4S,7R,9R,10R,12S)-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate	0
[(1S,2R,4S,7R,9R,10R,11S,12R)-11-acetyloxy-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate	0
deoxynivalenol +	870
isotrichodermol	0
trichothecin	0
verrucarin A	4
Path 2
Term	Annotations
CHEBI ontology	19808
subatomic particle	19806
composite particle	19806
hadron	19806
baryon	19806
nucleon	19806
atomic nucleus	19806
atom	19806
main group element atom	19756
p-block element atom	19756
carbon group element atom	19705
carbon atom	19702
organic molecular entity	19702
organic molecule	19655
organic cyclic compound	19468
organic heterocyclic compound	18848
organic heteromonocyclic compound	17773
saturated organic heteromonocyclic parent	11283
oxirane	11263
epoxide	11262
trichothecene	1525
(1S,2S,12S)-3,11-dihydroxy-1,2,5-trimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one	0
(2'E)-Roridin L-2	0
(3alpha)-3-Hydroxy-12,13-epoxytrichothec-9-ene-4,8,15-triyl triacetate	0
(S)-7-hydroxytrichothecolone acetate	0
12'-Hydroxyroridin E	0
13'-Acetyltrichoverrin B	0
14'-hydroxymytoxin B	0
14′-dehydrovertisporin	0
15-Acetoxyscirpene-3,4-diol 4-O-a-D-glucopyranoside	0
15-Acetoxyscirpenol	0
15-Acetyl-4-deoxynivalenol	0
15-Deacetylneosolaniol	0
15-acetyldeoxynivalenol	93
15-acetyltrichoverrol B	0
16-hydroxymytoxin B	0
16-hydroxyroridin E	0
2′,3′-deoxyroritoxin D	0
3'-Hydroxy-HT2 toxin	0
3'-Hydroxy-T2 Toxin	0
3'-Hydroxy-T2-triol	0
3,4,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate	0
3,7,8,15-Scirpenetetrol	0
3,8,15-Trihydroxy-12,13-epoxytrichothec-9-en-4-yl acetate	0
3-Acetoxyscirpene-4,15-diol	0
3-Hydroxyroridin E	0
3-acetyldeoxynivalenol	33
3′-epi-16-hydroxyverrucarin A	0
3′-epiverrucarin X	0
4,8-Diacetyl-T2-tetrol	0
4-((Z)-but-2-enoyloxy)-12,13-epoxy-16-hydroxytrichothec-9-ene	0
4-Acetoxyscirpene-3,15-diol	0
4-Deacetylneosolaniol	0
4-Propanoyl-HT2 toxin	0
6'-dehydroxytrichoverrin B	0
6′,12′-epoxymyrotoxin A	0
7'-hydroxymytoxin B	0
7-Hydroxytrichodermol	0
7alpha,8alpha-Dihydroxycalonectrin	0
7beta,8,beta2,'3'-diepoxyroridin H	0
7beta,8beta-epoxyisororidin E	0
7beta,8beta-epoxyroridin H	0
8-Acetoxyroridin E	0
8-Acetoxyroridin H	0
8-Acetyl-T2 tetrol	0
8-Butanoylneosolaniol	0
8-Hexanoylneosolaniol	0
8-Isobutanoylneosolaniol	0
8-Oxodiacetoxyscirpenol	0
8-Pentanoylneosolaniol	0
8-Propanoylneosolaniol	0
8-acetoxy T-2 tetraol	0
8-acetylneosolaniol	0
8-n-Hexanoylneosolaniol	0
8-n-Pentanoylneosolaniol	0
8a-Hydroxyisotrichoverrin A	0
9beta,10beta-Epoxyisotrichoverrin A	0
Acetyl-T2 Toxin	0
Acetyldeoxynivalenol	0
Acetyltrichothecolone	0
Anguidine	0
Anguidol	0
Chartarene D	0
Crotocin	0
DON-10-S-cysteine	0
DON-10-gamma-glutamylcysteine	0
DON-10-glutathione	0
DON-10-isoleucine	0
DON-10-leucine	0
DON-10-phenylalanine	0
DON-10-tyrosine	0
DON-13-S-cysteine	0
DON-15-penicillin G	0
DON-15-sulfate	0
DON-3-sulfate	0
DON-sulfonate 1	0
DON-sulfonate 2	0
DON-sulfonate 3	0
Deoxynivalenol 3-glucoside	2
Diacetoxyscirpenol	21
Epiroridin acid	0
Fusarenone X	42
HT-2 toxin +	800
Harzianum A	0
Isororidin E	0
Isororidin P	0
LSM-36622	0
Monoacetoxyscirpenol	0
Myotoxin A	0
Myrotoxin A	0
Myrotoxin B	0
NX-2	0
NX-3	0
NX-4	0
Neosolaniol	2
Nivalenol	58
Pentahydroxyscirpene	0
Roridin A	12
Roridin E	0
Roridin E acetate	0
Roridin F	0
Roridin H	0
Roridin J	0
Roridin K acetate	0
Roridin L	0
Roridin M	0
Roridin P	0
Roridin Q	0
Roridin R	0
Roridoxin A	0
Roridoxin B	0
Roridoxin C	0
Roritoxin A	0
Roritoxin B	0
Roritoxin C	0
Roritoxin D	0
Satratoxin H	3
Satratoxin H 12',13'-diacetate	0
Satratoxin H 12'-acetate	0
Satratoxin H 13'-acetate	0
Satratoxin I	0
Sporotrichiol	0
Stachybotrichodermone A	0
Standard Solution Nivalenol	0
T-2 Tetraol	0
T-2 toxin	798
T2 Toxin Triol	0
T2 Triol	0
Toxin T2 tetrol	0
Trichobreol A	0
Trichobreol B	0
Trichobreol C	0
Trichodermadiene	0
Trichodermadienediol A	0
Trichodermadienediol B	0
Trichodermarin C	0
Trichodermarin D	0
Trichodermarin E	0
Trichothecinol A	0
Trichothecinol B	0
Trichothecinol C	0
Trichoverrin A	0
Trichoverrin B	0
Trichoverrin C	0
Trichoverritone	0
Trichoverrol A	0
Trichoverrol B	0
Verrol	0
Verrol 4-acetate	0
Verrucarin L	0
Verrucarin L acetate	0
Verrucarin M	0
Verrucarin X	0
Verrucarin Y	0
Verrucarin Z	0
Verrucarin j	0
Verrucarol	0
YM-47524	0
YM-47525	0
[(1R,2R,4S,7R,9R,10R,12S)-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate	0
[(1S,2R,4S,7R,9R,10R,11S,12R)-11-acetyloxy-2-(acetyloxymethyl)-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate	0
deoxynivalenol +	870
isotrichodermol	0
trichothecin	0
verrucarin A	4

paths to the root