|
G |
Casp3 |
caspase 3 |
increases activity |
ISO |
HT-2 toxin results in increased activity of CASP3 protein |
CTD |
PMID:19428930 |
|
NCBI chr16:52,395,539...52,413,794
|
|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
decreases expression |
ISO |
HT-2 toxin results in decreased expression of CYP11A mRNA |
CTD |
PMID:22982764 |
|
NCBI chr 8:67,318,665...67,330,196
|
|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
decreases expression |
ISO |
HT-2 toxin results in decreased expression of CYP17A1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr 1:245,535,462...245,543,148
|
|
G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases expression |
ISO |
HT-2 toxin results in decreased expression of CYP19A1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr 8:63,449,148...63,476,534
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
HT-2 toxin results in increased expression of CYP1A1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr 8:66,991,940...66,998,014
|
|
G |
Ephx1 |
epoxide hydrolase 1 |
increases expression |
ISO |
HT-2 toxin results in increased expression of EPHX1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr13:95,246,079...95,275,852
|
|
G |
Gip |
gastric inhibitory polypeptide |
multiple interactions |
ISO |
HT-2 toxin results in increased expression of and results in increased secretion of GIP protein |
CTD |
PMID:28666375 |
|
NCBI chr10:81,465,070...81,473,216
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
decreases expression |
ISO |
HT-2 toxin results in decreased expression of HMGCR mRNA |
CTD |
PMID:22982764 |
|
NCBI chr 2:29,732,163...29,754,276
|
|
G |
Hsd17b1 |
hydroxysteroid (17-beta) dehydrogenase 1 |
increases expression |
ISO |
HT-2 toxin results in increased expression of HSD17B1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr10:86,009,728...86,011,928
|
|
|
G |
A2m |
alpha-2-macroglobulin |
multiple interactions decreases expression |
ISO |
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of A2M mRNA]; Selenium promotes the reaction [T-2 Toxin results in decreased expression of A2M protein] T-2 Toxin results in decreased expression of A2M mRNA; T-2 Toxin results in decreased expression of A2M protein |
CTD |
PMID:21144892 |
|
NCBI chr 4:154,897,770...154,947,787
|
|
G |
Aars1 |
alanyl-tRNA synthetase 1 |
decreases expression |
EXP ISO |
T-2 Toxin results in decreased expression of AARS1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr19:38,999,130...39,021,152
|
|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ABCB1A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:26,312,403...26,488,456
|
|
G |
Abraxas2 |
abraxas 2, BRISC complex subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of ABRAXAS2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:187,647,078...187,672,660
|
|
G |
Acan |
aggrecan |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ACAN mRNA; T-2 Toxin results in decreased expression of ACAN protein |
CTD |
PMID:16624732 PMID:18196609 PMID:22800716 PMID:31863870 |
|
NCBI chr 1:142,390,951...142,453,779
|
|
G |
Acat2 |
acetyl-CoA acetyltransferase 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of ACAT2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:50,100,840...50,118,886
|
|
G |
Acly |
ATP citrate lyase |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ACLY mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:85,412,045...85,464,253
|
|
G |
Aco2 |
aconitase 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of ACO2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:113,385,677...113,428,794
|
|
G |
Actb |
actin, beta |
affects expression |
EXP |
T-2 Toxin affects the expression of ACTB protein |
CTD |
PMID:26141394 |
|
NCBI chr12:16,776,664...16,779,634
|
|
G |
Actr1a |
actin related protein 1A |
increases expression |
ISO |
T-2 Toxin results in increased expression of ACTR1A mRNA; T-2 Toxin results in increased expression of ACTR1A protein |
CTD |
PMID:34581912 |
|
NCBI chr 1:245,237,821...245,256,618
|
|
G |
Adam9 |
ADAM metallopeptidase domain 9 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ADAM9 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr16:73,725,186...73,804,284
|
|
G |
Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ADAMTS4 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr13:86,203,011...86,212,500
|
|
G |
Adamts5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ADAMTS5 mRNA |
CTD |
PMID:18196609 PMID:22800716 |
|
NCBI chr11:25,000,627...25,047,205
|
|
G |
Adk |
adenosine kinase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ADK protein |
CTD |
PMID:34581912 |
|
NCBI chr15:2,912,543...3,295,745
|
|
G |
Adprh |
ADP-ribosylarginine hydrolase |
affects expression |
EXP |
T-2 Toxin affects the expression of ADPRH protein |
CTD |
PMID:26141394 |
|
NCBI chr11:62,299,831...62,306,170
|
|
G |
Afg1l |
AFG1 like ATPase |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to AFG1L] |
CTD |
PMID:36863559 |
|
NCBI chr20:45,798,344...45,967,997
|
|
G |
Afg2a |
AFG2 AAA ATPase homolog A |
increases expression |
EXP |
T-2 Toxin results in increased expression of AFG2A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:120,306,417...120,497,707
|
|
G |
Ahcy |
adenosylhomocysteinase |
increases expression |
ISO |
T-2 Toxin results in increased expression of AHCY protein |
CTD |
PMID:34581912 |
|
NCBI chr 3:164,029,338...164,044,562
|
|
G |
Ahr |
aryl hydrocarbon receptor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of AHR protein |
CTD |
PMID:31470059 |
|
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Aimp2 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of AIMP2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:10,701,194...10,710,772
|
|
G |
Ak2 |
adenylate kinase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of AK2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:146,609,469...146,649,008
|
|
G |
Akap3 |
A-kinase anchoring protein 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of AKAP3 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:159,688,049...159,714,067
|
|
G |
Akap4 |
A-kinase anchoring protein 4 |
increases expression |
ISO |
T-2 Toxin results in increased expression of AKAP4 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr X:15,435,391...15,445,684
|
|
G |
Akirin2 |
akirin 2 |
increases expression |
EXP ISO |
T-2 Toxin results in increased expression of AKIRIN2 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 5:49,108,231...49,122,566
|
|
G |
Akna |
AT-hook transcription factor |
decreases expression multiple interactions affects localization |
EXP |
T-2 Toxin results in decreased expression of AKNA mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter]; T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter] T-2 Toxin affects the localization of AKNA protein |
CTD |
PMID:26141394 PMID:29079362 |
|
NCBI chr 5:76,777,415...76,824,380
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of AKT1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Akt1s1 |
AKT1 substrate 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of AKT1S1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:104,469,823...104,476,168
|
|
G |
Alas1 |
5'-aminolevulinate synthase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ALAS1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:106,876,514...106,889,917
|
|
G |
Alas2 |
5'-aminolevulinate synthase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ALAS2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr X:19,463,146...19,486,526
|
|
G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
affects expression increases expression |
EXP |
T-2 Toxin affects the expression of ALDH1A1 protein T-2 Toxin results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:218,000,470...218,152,962
|
|
G |
Aldoc |
aldolase, fructose-bisphosphate C |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ALDOC mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:63,715,544...63,719,133
|
|
G |
Alpl |
alkaline phosphatase, biomineralization associated |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ALPL protein |
CTD |
PMID:35289972 |
|
NCBI chr 5:155,234,770...155,289,785
|
|
G |
Angptl7 |
angiopoietin like 7 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ANGPTL7 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:164,215,223...164,220,408
|
|
G |
Anln |
anillin, actin binding protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ANLN mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:20,858,227...20,921,602
|
|
G |
Anp32b |
acidic nuclear phosphoprotein 32 family member B |
affects expression |
EXP |
T-2 Toxin affects the expression of ANP32B protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:65,538,872...65,561,305
|
|
G |
Anxa1 |
annexin A1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ANXA1 protein |
CTD |
PMID:34581912 |
|
NCBI chr 1:227,287,713...227,306,739
|
|
G |
Anxa5 |
annexin A5 |
affects expression |
EXP |
T-2 Toxin affects the expression of ANXA5 protein |
CTD |
PMID:26141394 |
|
NCBI chr 2:121,242,133...121,272,935
|
|
G |
Apoe |
apolipoprotein E |
increases expression |
EXP |
T-2 Toxin results in increased expression of APOE mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:88,481,889...88,485,816
|
|
G |
App |
amyloid beta precursor protein |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of APP mRNA |
CTD |
PMID:26141394 |
|
NCBI chr11:37,506,207...37,724,351
|
|
G |
Aprt |
adenine phosphoribosyl transferase |
affects expression |
EXP |
T-2 Toxin affects the expression of APRT protein |
CTD |
PMID:26141394 |
|
NCBI chr19:50,626,201...50,628,491
|
|
G |
Ar |
androgen receptor |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to AR] |
CTD |
PMID:36863559 |
|
NCBI chr X:63,104,771...63,273,934
|
|
G |
Areg |
amphiregulin |
multiple interactions |
ISO |
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA] |
CTD |
PMID:30951242 |
|
NCBI chr14:17,256,384...17,265,641
|
|
G |
Arhgap18 |
Rho GTPase activating protein 18 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ARHGAP18 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:20,222,948...20,456,827
|
|
G |
Arl5c |
ARF like GTPase 5C |
increases expression |
EXP |
T-2 Toxin results in increased expression of ARL5C mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:82,985,213...82,993,425
|
|
G |
Arrb2 |
arrestin, beta 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ARRB2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:55,645,539...55,653,485
|
|
G |
Arsa |
arylsulfatase A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ARSA mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:120,542,788...120,547,577
|
|
G |
Asap3 |
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ASAP3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:153,716,988...153,757,787
|
|
G |
Asb14 |
ankyrin repeat and SOCS box-containing 14 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ASB14 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr16:2,095,567...2,123,259
|
|
G |
Asb5 |
ankyrin repeat and SOCS box-containing 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ASB5 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr16:37,237,869...37,305,207
|
|
G |
Asb6 |
ankyrin repeat and SOCS box-containing 6 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ASB6 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:14,110,628...14,115,274
|
|
G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ASNS mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr 4:36,752,061...36,769,970
|
|
G |
Ass1 |
argininosuccinate synthase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ASS1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr 3:14,747,355...14,796,909
|
|
G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression |
ISO |
salubrinal promotes the reaction [T-2 Toxin results in increased expression of ATF4 protein] |
CTD |
PMID:34673134 |
|
NCBI chr 7:113,684,681...113,686,739
|
|
G |
Atg12 |
autophagy related 12 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ATG12 protein |
CTD |
PMID:26138683 |
|
NCBI chr18:41,638,841...41,649,311
|
|
G |
Atg14 |
autophagy related 14 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ATG14 mRNA |
CTD |
PMID:26138683 |
|
NCBI chr15:23,275,457...23,306,817
|
|
G |
Atg3 |
autophagy related 3 |
increases expression multiple interactions |
EXP ISO |
T-2 Toxin results in increased expression of ATG3 protein ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein] T-2 Toxin results in increased expression of ATG3 mRNA; T-2 Toxin results in increased expression of ATG3 protein |
CTD |
PMID:29870751 PMID:32240701 |
|
NCBI chr11:55,624,914...55,653,249
|
|
G |
Atg5 |
autophagy related 5 |
affects expression increases expression multiple interactions |
EXP ISO |
T-2 Toxin affects the expression of ATG5 protein T-2 Toxin results in increased expression of ATG5 protein 3-methyladenine affects the reaction [T-2 Toxin affects the expression of ATG5 protein] |
CTD |
PMID:29413859 PMID:35289972 PMID:36402210 |
|
NCBI chr20:49,380,835...49,471,826
|
|
G |
Atic |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ATIC protein |
CTD |
PMID:34581912 |
|
NCBI chr 9:73,164,846...73,184,897
|
|
G |
Atm |
ATM serine/threonine kinase |
increases phosphorylation decreases expression |
ISO |
T-2 Toxin results in increased phosphorylation of ATM protein T-2 Toxin results in decreased expression of ATM mRNA |
CTD |
PMID:20150440 PMID:34581912 |
|
NCBI chr 8:62,724,939...62,829,040
|
|
G |
Atp11a |
ATPase phospholipid transporting 11A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ATP11A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr16:76,657,752...76,767,640
|
|
G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ATP1A1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:191,709,311...191,737,414
|
|
G |
Atp5f1a |
ATP synthase F1 subunit alpha |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP5F1A protein |
CTD |
PMID:26141394 |
|
NCBI chr18:73,567,537...73,575,473
|
|
G |
Atp5f1b |
ATP synthase F1 subunit beta |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP5F1B protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:515,454...521,858
|
|
G |
Atp5pd |
ATP synthase peripheral stalk subunit d |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP5PD protein |
CTD |
PMID:26141394 |
|
NCBI chr10:100,657,700...100,662,960
|
|
G |
Atp6v1a |
ATPase H+ transporting V1 subunit A |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP6V1A protein |
CTD |
PMID:26141394 |
|
NCBI chr11:70,066,800...70,120,603
|
|
G |
Atp6v1b2 |
ATPase H+ transporting V1 subunit B2 |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP6V1B2 protein |
CTD |
PMID:26141394 |
|
NCBI chr16:20,617,515...20,641,651
|
|
G |
Atp8b2 |
ATPase phospholipid transporting 8B2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ATP8B2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:175,378,514...175,402,265
|
|
G |
Aup1 |
AUP1, lipid droplet regulating VLDL assembly factor |
increases expression |
ISO |
T-2 Toxin results in increased expression of AUP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:115,560,274...115,563,346
|
|
G |
Axl |
Axl receptor tyrosine kinase |
increases expression |
ISO |
T-2 Toxin results in increased expression of AXL mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:90,392,864...90,424,123
|
|
G |
B2m |
beta-2 microglobulin |
increases expression |
ISO |
T-2 Toxin results in increased expression of B2M protein |
CTD |
PMID:33508416 |
|
NCBI chr 3:129,549,236...129,555,354
|
|
G |
Bag5 |
BAG cochaperone 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of BAG5 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:136,589,623...136,593,278
|
|
G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of BAK1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:5,102,334...5,111,615
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
affects localization multiple interactions increases expression affects expression decreases expression |
ISO EXP |
T-2 Toxin affects the localization of BAX protein Selenium inhibits the reaction [T-2 Toxin results in increased expression of BAX mRNA] T-2 Toxin results in increased expression of BAX mRNA; T-2 Toxin results in increased expression of BAX protein T-2 Toxin affects the expression of BAX protein T-2 Toxin results in decreased expression of BAX protein |
CTD |
PMID:16307838 PMID:19524637 PMID:19541794 PMID:21296132 PMID:26138683 PMID:26314264 PMID:28697680 PMID:29413859 PMID:29432840 PMID:29870751 PMID:33508416 PMID:35289972 More...
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NCBI chr 1:105,076,472...105,081,906
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of BBC3 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:86,141,450...86,150,666
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G |
Bcat1 |
branched chain amino acid transaminase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of BCAT1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:179,695,662...179,777,973
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G |
Bccip |
BRCA2 and CDKN1A interacting protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of BCCIP mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:188,512,544...188,524,957
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression decreases expression increases activity |
EXP ISO |
T-2 Toxin results in increased expression of BCL2 mRNA; T-2 Toxin results in increased expression of BCL2 protein T-2 Toxin results in decreased expression of BCL2 mRNA T-2 Toxin results in decreased expression of BCL2 mRNA; T-2 Toxin results in decreased expression of BCL2 protein T-2 Toxin results in increased activity of BCL2 protein |
CTD |
PMID:19524637 PMID:21296132 PMID:28697680 PMID:29870751 PMID:33508416 PMID:34581912 PMID:35289972 More...
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NCBI chr13:23,204,464...23,366,900
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression affects expression |
ISO EXP |
T-2 Toxin results in decreased expression of BCL2L1 mRNA; T-2 Toxin results in decreased expression of BCL2L1 protein T-2 Toxin affects the expression of BCL2L1 protein |
CTD |
PMID:29413859 PMID:29432840 |
|
NCBI chr 3:161,713,777...161,764,844
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G |
Becn1 |
beclin 1 |
increases expression multiple interactions affects expression |
EXP ISO |
T-2 Toxin results in increased expression of BECN1 mRNA 3-methyladenine inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Selenium deficiency inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Sirolimus promotes the reaction [T-2 Toxin results in increased expression of BECN1 mRNA] T-2 Toxin results in increased expression of BECN1 protein T-2 Toxin affects the expression of BECN1 protein 3-methyladenine affects the reaction [T-2 Toxin affects the expression of BECN1 protein] |
CTD |
PMID:30629952 PMID:35289972 PMID:36402210 |
|
NCBI chr10:86,731,649...86,747,002
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G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of BGLAP protein |
CTD |
PMID:35289972 |
|
NCBI chr 2:176,136,341...176,137,318
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G |
Bid |
BH3 interacting domain death agonist |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of BID protein |
CTD |
PMID:29432840 |
|
NCBI chr 4:155,785,366...155,808,775
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G |
Bnip3l |
BCL2 interacting protein 3 like |
increases expression |
EXP |
T-2 Toxin results in increased expression of BNIP3L mRNA |
CTD |
PMID:29870751 |
|
NCBI chr15:45,350,081...45,373,213
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|
G |
Bop1 |
BOP1 ribosomal biogenesis factor |
increases expression |
ISO |
T-2 Toxin results in increased expression of BOP1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 7:108,172,062...108,195,875
|
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G |
Bpnt1 |
3'(2'), 5'-bisphosphate nucleotidase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of BPNT1 protein |
CTD |
PMID:26141394 |
|
NCBI chr13:96,865,634...96,893,506
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G |
Brip1 |
BRCA1 interacting DNA helicase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of BRIP1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:71,402,035...71,528,083
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G |
Bud23 |
BUD23, rRNA methyltransferase and ribosome maturation factor |
increases expression |
ISO |
T-2 Toxin results in increased expression of BUD23 mRNA |
CTD |
PMID:31863870 |
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NCBI chr12:21,629,551...21,640,758
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G |
C5 |
complement C5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of C5 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:38,668,174...38,759,468
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G |
Calm1 |
calmodulin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CALM1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 6:125,217,191...125,227,855
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G |
Capns1 |
calpain, small subunit 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CAPNS1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:85,444,613...85,454,861
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G |
Cars1 |
cysteinyl-tRNA synthetase 1 |
decreases expression |
EXP ISO |
T-2 Toxin results in decreased expression of CARS1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 1:208,183,092...208,225,425
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G |
Casp12 |
caspase 12 |
multiple interactions increases expression |
ISO EXP |
salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA] salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of CASP12 protein] T-2 Toxin results in increased expression of CASP12 mRNA; T-2 Toxin results in increased expression of CASP12 protein |
CTD |
PMID:34673134 |
|
NCBI chr 8:10,927,188...10,954,442
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases expression affects expression |
EXP ISO |
3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; Selenium deficiency promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; Sirolimus inhibits the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP3 protein T-2 Toxin results in increased expression of CASP3 mRNA T-2 Toxin results in increased expression of CASP3 mRNA; T-2 Toxin results in increased expression of CASP3 protein; T-2 Toxin results in increased expression of CASP3 protein modified form Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein]; T-2 Toxin results in increased expression of and results in increased activity of CASP3 protein; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein] T-2 Toxin affects the expression of CASP3 protein |
CTD |
PMID:19428930 PMID:19524637 PMID:19541794 PMID:21295106 PMID:21296132 PMID:26138683 PMID:28697680 PMID:29413859 PMID:29432840 PMID:29567467 PMID:29870751 PMID:30629952 PMID:33508416 PMID:35289972 More...
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NCBI chr16:52,395,539...52,413,794
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G |
Casp7 |
caspase 7 |
increases activity |
ISO |
T-2 Toxin results in increased activity of CASP7 protein |
CTD |
PMID:19524637 |
|
NCBI chr 1:265,442,647...265,481,938
|
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G |
Casp8 |
caspase 8 |
increases expression increases activity multiple interactions |
EXP ISO |
T-2 Toxin results in increased expression of CASP8 mRNA T-2 Toxin results in increased activity of CASP8 protein Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein] |
CTD |
PMID:26141394 PMID:29432840 PMID:29567467 PMID:29870751 |
|
NCBI chr 9:67,747,109...67,806,699
|
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G |
Casp9 |
caspase 9 |
increases activity multiple interactions increases expression |
ISO EXP |
T-2 Toxin results in increased activity of CASP9 protein 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP9 protein T-2 Toxin results in increased expression of CASP9 mRNA Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein]; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein] |
CTD |
PMID:19524637 PMID:21296132 PMID:29432840 PMID:29567467 PMID:33508416 PMID:35289972 More...
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|
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G |
Cat |
catalase |
increases activity decreases expression multiple interactions decreases activity increases expression |
ISO EXP |
T-2 Toxin results in increased activity of CAT protein T-2 Toxin results in decreased expression of CAT mRNA T-2 Toxin affects the expression of and affects the activity of CAT protein T-2 Toxin results in decreased activity of CAT protein T-2 Toxin results in increased expression of CAT mRNA |
CTD |
PMID:19526462 PMID:21112371 PMID:23929680 PMID:27842451 PMID:29432840 PMID:29870751 PMID:30091165 PMID:33508416 PMID:34581912 More...
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NCBI chr 3:110,297,340...110,329,526
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G |
Cbr1 |
carbonyl reductase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CBR1 protein |
CTD |
PMID:26141394 |
|
NCBI chr11:32,860,571...32,862,981
|
|
G |
Ccdc137 |
coiled-coil domain containing 137 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CCDC137 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:105,730,776...105,737,158
|
|
G |
Ccdc34 |
coiled-coil domain containing 34 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CCDC34 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:96,553,074...96,588,310
|
|
G |
Ccn3 |
cellular communication network factor 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCN3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:87,983,788...87,990,810
|
|
G |
Ccnb1ip1 |
cyclin B1 interacting protein 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CCNB1IP1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr15:24,014,905...24,031,357
|
|
G |
Ccnb2 |
cyclin B2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCNB2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:79,968,459...79,981,717
|
|
G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO EXP |
T-2 Toxin results in decreased expression of CCND1 mRNA T-2 Toxin results in decreased expression of CCND1 mRNA; T-2 Toxin results in decreased expression of CCND1 protein |
CTD |
PMID:22454431 PMID:29567467 PMID:35289972 |
|
NCBI chr 1:209,518,288...209,527,986
|
|
G |
Ccng1 |
cyclin G1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCNG1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:25,678,503...25,684,876
|
|
G |
Ccng2 |
cyclin G2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCNG2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:15,088,694...15,097,190
|
|
G |
Cct2 |
chaperonin containing TCP1 subunit 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CCT2 protein |
CTD |
PMID:34581912 |
|
NCBI chr 7:54,578,654...54,591,428
|
|
G |
Cd24 |
CD24 molecule |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CD24 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr20:47,074,353...47,079,662
|
|
G |
Cd274 |
CD274 molecule |
increases expression |
ISO |
T-2 Toxin results in increased expression of CD274 protein |
CTD |
PMID:36115646 |
|
NCBI chr 1:236,526,215...236,549,956
|
|
G |
Cd40 |
CD40 molecule |
increases expression |
ISO |
T-2 Toxin results in increased expression of CD40 mRNA |
CTD |
PMID:36775139 |
|
NCBI chr 3:174,209,113...174,224,592
|
|
G |
Cd44 |
CD44 molecule |
multiple interactions decreases expression |
ISO |
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein] T-2 Toxin results in decreased expression of CD44 mRNA; T-2 Toxin results in decreased expression of CD44 protein |
CTD |
PMID:18196609 |
|
NCBI chr 3:109,610,824...109,699,776
|
|
G |
Cd55 |
CD55 molecule (Cromer blood group) |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CD55 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr13:44,409,574...44,438,913
|
|
G |
Cdc42bpa |
CDC42 binding protein kinase alpha |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CDC42BPA mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:94,215,359...94,435,681
|
|
G |
Cdca5 |
cell division cycle associated 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDCA5 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:212,807,863...212,821,313
|
|
G |
Cdca7 |
cell division cycle associated 7 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDCA7 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:77,730,315...77,740,950
|
|
G |
Cdca8 |
cell division cycle associated 8 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDCA8 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 5:142,461,082...142,483,336
|
|
G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CDK4 mRNA; T-2 Toxin results in decreased expression of CDK4 protein |
CTD |
PMID:29567467 |
|
NCBI chr 7:64,771,453...64,774,891
|
|
G |
Cdk5 |
cyclin-dependent kinase 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CDK5 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:11,647,098...11,651,606
|
|
G |
Cdk5rap1 |
CDK5 regulatory subunit associated protein 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDK5RAP1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:163,189,435...163,333,003
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO EXP |
T-2 Toxin results in increased expression of CDKN1A mRNA T-2 Toxin results in increased expression of CDKN1A mRNA; T-2 Toxin results in increased expression of CDKN1A protein |
CTD |
PMID:22454431 PMID:29567467 |
|
NCBI chr20:7,150,820...7,161,373
|
|
G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
increases expression |
EXP |
T-2 Toxin results in increased expression of CDKN2A mRNA; T-2 Toxin results in increased expression of CDKN2A protein |
CTD |
PMID:29567467 |
|
NCBI chr 5:109,100,763...109,114,448
|
|
G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CDKN3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr15:22,502,299...22,513,725
|
|
G |
Cenpe |
centromere protein E |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CENPE mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:226,310,970...226,369,636
|
|
G |
Cenpf |
centromere protein F |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CENPF mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:103,715,344...103,760,931
|
|
G |
Cep135 |
centrosomal protein 135 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CEP135 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:31,884,774...31,950,050
|
|
G |
Cfap96 |
cilia and flagella associated protein 96 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CFAP96 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:46,291,075...46,315,616
|
|
G |
Cfl1 |
cofilin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CFL1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:212,227,124...212,230,656
|
|
G |
Cga |
glycoprotein hormones, alpha polypeptide |
multiple interactions |
ISO |
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA] |
CTD |
PMID:25962641 PMID:30951242 |
|
NCBI chr 5:54,283,109...54,295,464
|
|
G |
Cgrrf1 |
cell growth regulator with ring finger domain 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CGRRF1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr15:20,088,564...20,109,042
|
|
G |
Chek2 |
checkpoint kinase 2 |
multiple interactions increases activity |
ISO |
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of CHEK2 protein] |
CTD |
PMID:20150440 |
|
NCBI chr12:51,448,838...51,481,159
|
|
G |
Chpf |
chondroitin polymerizing factor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CHPF mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 9:76,963,178...76,967,878
|
|
G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CHRNA4 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 3:168,136,246...168,157,839
|
|
G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CHRNB2 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 2:175,181,402...175,189,619
|
|
G |
Ciita |
class II, major histocompatibility complex, transactivator |
increases expression |
ISO |
T-2 Toxin results in increased expression of CIITA mRNA |
CTD |
PMID:36775139 |
|
NCBI chr10:5,139,947...5,187,493
|
|
G |
Cit |
citron rho-interacting serine/threonine kinase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CIT mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:46,263,881...46,425,642
|
|
G |
Ckb |
creatine kinase B |
affects expression |
EXP |
T-2 Toxin affects the expression of CKB protein |
CTD |
PMID:26141394 |
|
NCBI chr 6:136,550,583...136,553,464
|
|
G |
Ckmt2 |
creatine kinase, mitochondrial 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CKMT2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:24,815,008...24,845,511
|
|
G |
Cldn3 |
claudin 3 |
multiple interactions decreases expression |
ISO |
illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN3 mRNA] |
CTD |
PMID:27153755 |
|
NCBI chr12:27,345,075...27,346,547
|
|
G |
Cldn4 |
claudin 4 |
multiple interactions decreases expression |
ISO |
illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN4 mRNA] |
CTD |
PMID:27153755 |
|
NCBI chr12:27,388,160...27,389,958
|
|
G |
Clic1 |
chloride intracellular channel 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of CLIC1 protein |
CTD |
PMID:26141394 |
|
NCBI chr20:3,769,522...3,778,367
|
|
G |
Cln8 |
CLN8, transmembrane ER and ERGIC protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of CLN8 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr16:74,749,662...74,759,553
|
|
G |
Clu |
clusterin |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of CLU mRNA T-2 Toxin results in increased expression of CLU mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr15:40,161,068...40,200,315
|
|
G |
Cnpy2 |
canopy FGF signaling regulator 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of CNPY2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:748,877...754,352
|
|
G |
Cntf |
ciliary neurotrophic factor |
increases expression |
EXP |
T-2 Toxin results in increased expression of CNTF mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:209,887,854...209,889,877
|
|
G |
Coa5 |
cytochrome C oxidase assembly factor 5 |
multiple interactions increases expression |
EXP |
GABPA promotes the reaction [T-2 Toxin results in increased expression of COA5 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to COA5] |
CTD |
PMID:36863559 |
|
NCBI chr 9:39,651,459...39,664,870
|
|
G |
Col10a1 |
collagen type X alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL10A1 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr20:38,183,103...38,189,488
|
|
G |
Col11a1 |
collagen type XI alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL11A1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:201,820,715...202,013,853
|
|
G |
Col15a1 |
collagen type XV alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL15A1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:66,297,546...66,403,172
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL1A1 mRNA |
CTD |
PMID:22800716 PMID:35289972 |
|
NCBI chr10:80,380,458...80,397,461
|
|
G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions decreases expression |
ISO |
3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of COL1A2 protein] |
CTD |
PMID:36402210 |
|
NCBI chr 4:33,518,557...33,553,484
|
|
G |
Col2a1 |
collagen type II alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL2A1 mRNA |
CTD |
PMID:22800716 PMID:34673134 |
|
NCBI chr 7:130,977,561...131,006,627
|
|
G |
Col9a1 |
collagen type IX alpha 1 chain |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COL9A1 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr 9:26,585,034...26,668,222
|
|
G |
Colgalt2 |
collagen beta(1-O)galactosyltransferase 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of COLGALT2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:64,523,641...64,628,295
|
|
G |
Cope |
COPI coat complex subunit epsilon |
affects expression |
EXP |
T-2 Toxin affects the expression of COPE protein |
CTD |
PMID:26141394 |
|
NCBI chr16:19,148,832...19,159,052
|
|
G |
Copz1 |
COPI coat complex subunit zeta 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of COPZ1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:134,409,523...134,435,661
|
|
G |
Coq5 |
coenzyme Q5, methyltransferase |
increases expression |
ISO |
T-2 Toxin results in increased expression of COQ5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:41,316,922...41,333,855
|
|
G |
Coro1c |
coronin 1C |
increases expression |
ISO |
T-2 Toxin results in increased expression of CORO1C mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:42,713,024...42,785,179
|
|
G |
Coro2b |
coronin 2B |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CORO2B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:62,906,861...63,017,295
|
|
G |
Cox15 |
cytochrome c oxidase assembly homolog COX15 |
increases expression |
ISO |
T-2 Toxin results in increased expression of COX15 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:252,554,811...252,571,471
|
|
G |
Cox19 |
cytochrome c oxidase assembly factor COX19 |
increases expression |
ISO |
T-2 Toxin results in increased expression of COX19 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:15,303,535...15,313,014
|
|
G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
multiple interactions decreases expression |
ISO |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of COX4I1 protein] |
CTD |
PMID:27363784 |
|
NCBI chr19:65,630,383...65,636,623
|
|
G |
Cox6c |
cytochrome c oxidase subunit 6C |
affects expression |
EXP |
T-2 Toxin affects the expression of COX6C protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:67,129,265...67,142,001
|
|
G |
Cox6c-ps1 |
cytochrome c oxidase subunit VIc, pseudogene |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of COX6C-PS1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr19:52,192,612...52,193,470
|
|
G |
Cpap |
centrosome assembly and centriole elongation protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CPAP mRNA |
CTD |
PMID:34581912 |
|
NCBI chr15:30,627,206...30,690,384
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
affects localization multiple interactions |
EXP |
T-2 Toxin affects the localization of CREB1 protein modified form T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter] |
CTD |
PMID:29079362 |
|
NCBI chr 9:73,397,333...73,466,339
|
|
G |
Creb3l1 |
cAMP responsive element binding protein 3-like 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CREB3L1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:98,408,240...98,449,104
|
|
G |
Creb5 |
cAMP responsive element binding protein 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CREB5 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr 4:83,723,587...84,124,786
|
|
G |
Crem |
cAMP responsive element modulator |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CREM mRNA |
CTD |
PMID:26141394 |
|
NCBI chr17:58,932,011...59,001,160
|
|
G |
Crtc3 |
CREB regulated transcription coactivator 3 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CRTC3 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:143,962,038...144,064,324
|
|
G |
Cryab |
crystallin, alpha B |
increases expression |
ISO |
T-2 Toxin results in increased expression of CRYAB mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:59,989,885...59,995,532
|
|
G |
Cs |
citrate synthase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CS protein |
CTD |
PMID:34581912 |
|
NCBI chr 7:1,348,389...1,374,624
|
|
G |
Csf1 |
colony stimulating factor 1 |
increases expression |
EXP ISO |
T-2 Toxin results in increased expression of CSF1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 2:198,065,400...198,084,774
|
|
G |
Csrnp1 |
cysteine and serine rich nuclear protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of CSRNP1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:128,582,364...128,594,163
|
|
G |
Cst3 |
cystatin C |
increases expression |
ISO |
T-2 Toxin results in increased expression of CST3 protein |
CTD |
PMID:33508416 |
|
NCBI chr 3:136,336,923...136,340,796
|
|
G |
Cth |
cystathionine gamma-lyase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CTH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:249,634,731...249,661,066
|
|
G |
Ctnnb1 |
catenin beta 1 |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of CTNNB1 mRNA; T-2 Toxin results in decreased expression of CTNNB1 protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of CTNNB1 protein] |
CTD |
PMID:35289972 PMID:36402210 |
|
NCBI chr 8:129,517,576...129,544,661
|
|
G |
Ctrl |
chymotrypsin-like |
affects expression |
EXP |
T-2 Toxin affects the expression of CTRB1 protein |
CTD |
PMID:26141394 |
|
NCBI chr19:33,827,279...33,829,129
|
|
G |
Ctsa |
cathepsin A |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CTSA mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:153,569,106...153,574,983
|
|
G |
Cwc27 |
CWC27 spliceosome associated cyclophilin |
increases expression |
ISO |
T-2 Toxin results in increased expression of CWC27 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:35,764,674...35,975,908
|
|
G |
Cyb5r1 |
cytochrome b5 reductase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CYB5R1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:48,401,061...48,407,466
|
|
G |
Cyc1 |
cytochrome c-1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of CYC1 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 7:109,947,750...109,950,142
|
|
G |
Cycs |
cytochrome c, somatic |
affects localization |
ISO |
T-2 Toxin affects the localization of CYCS protein |
CTD |
PMID:19541794 |
|
NCBI chr 4:80,982,667...80,984,767
|
|
G |
Cyfip1 |
cytoplasmic FMR1 interacting protein 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CYFIP1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:115,842,754...115,935,163
|
|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions decreases expression increases expression |
ISO EXP |
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA T-2 Toxin results in decreased expression of CYP11A1 mRNA T-2 Toxin results in increased expression of CYP11A1 mRNA |
CTD |
PMID:25962641 PMID:26141394 PMID:34581912 |
|
NCBI chr 8:67,318,665...67,330,196
|
|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein |
CTD |
PMID:25962641 |
|
NCBI chr 1:245,535,462...245,543,148
|
|
G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of CYP19A1 mRNA 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA] |
CTD |
PMID:22982764 PMID:30951242 |
|
NCBI chr 8:63,449,148...63,476,534
|
|
G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO |
Dactinomycin inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; Resveratrol inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter]; T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter] T-2 Toxin results in increased expression of CYP1A1 mRNA; T-2 Toxin results in increased expression of CYP1A1 protein |
CTD |
PMID:21453744 PMID:22982764 PMID:31470059 |
|
NCBI chr 8:66,991,940...66,998,014
|
|
G |
Cytl1 |
cytokine like 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of CYTL1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr14:73,053,876...73,058,886
|
|
G |
Dars2 |
aspartyl-tRNA synthetase 2 (mitochondrial) |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of DARS2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:73,308,726...73,336,558
|
|
G |
Dcps |
decapping enzyme, scavenger |
increases expression |
ISO |
T-2 Toxin results in increased expression of DCPS mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:41,729,507...41,782,222
|
|
G |
Dcx |
doublecortin |
increases expression |
ISO |
T-2 Toxin results in increased expression of DCX mRNA |
CTD |
PMID:26314264 |
|
NCBI chr X:107,430,767...107,573,612
|
|
G |
Dcxr |
dicarbonyl and L-xylulose reductase |
increases expression |
ISO |
T-2 Toxin results in increased expression of DCXR mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:106,006,404...106,008,293
|
|
G |
Ddb2 |
damage specific DNA binding protein 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of DDB2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:77,185,114...77,207,650
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions |
EXP ISO |
T-2 Toxin results in increased expression of DDIT3 mRNA; T-2 Toxin results in increased expression of DDIT3 protein Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein] salubrinal inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein] |
CTD |
PMID:26141394 PMID:29454614 PMID:34673134 |
|
NCBI chr 7:65,001,695...65,006,517
|
|
G |
Ddit4 |
DNA-damage-inducible transcript 4 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DDIT4 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:28,434,938...28,437,037
|
|
G |
Ddx52 |
DExD-box helicase 52 |
increases expression |
ISO |
T-2 Toxin results in increased expression of DDX52 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:69,322,062...69,344,856
|
|
G |
Ddx55 |
DEAD-box helicase 55 |
multiple interactions increases expression |
EXP |
GABPA promotes the reaction [T-2 Toxin results in increased expression of DDX55 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to DDX55] |
CTD |
PMID:36863559 |
|
NCBI chr12:32,034,462...32,050,218
|
|
G |
Ddx56 |
DEAD-box helicase 56 |
increases expression |
ISO |
T-2 Toxin results in increased expression of DDX56 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:81,112,008...81,122,331
|
|
G |
Dffa |
DNA fragmentation factor subunit alpha |
increases expression |
ISO |
T-2 Toxin results in increased expression of DFFA mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 5:159,540,715...159,553,639
|
|
G |
Dgcr8 |
DGCR8 microprocessor complex subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of DGCR8 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr11:96,208,959...96,241,560
|
|
G |
Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DHCR24 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr 5:121,344,552...121,371,124
|
|
G |
Diablo |
diablo, IAP-binding mitochondrial protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of DIABLO protein |
CTD |
PMID:34581912 |
|
NCBI chr12:38,716,668...38,731,285
|
|
G |
Disc1 |
DISC1 scaffold protein |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to DISC1] |
CTD |
PMID:36863559 |
|
NCBI chr19:53,014,201...53,223,617
|
|
G |
Dnajc10 |
DnaJ heat shock protein family (Hsp40) member C10 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DNAJC10 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:65,232,031...65,272,732
|
|
G |
Dnajc4 |
DnaJ heat shock protein family (Hsp40) member C4 |
affects expression |
EXP |
T-2 Toxin affects the expression of DNAJC4 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:204,178,189...204,182,412
|
|
G |
Dnase1l1 |
deoxyribonuclease 1-like 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DNASE1L1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr X:152,056,942...152,065,518
|
|
G |
Dnase2 |
deoxyribonuclease 2, lysosomal |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DNASE2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr19:23,244,656...23,247,376
|
|
G |
Dnm1l |
dynamin 1-like |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of DNM1L mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to DNM1L] |
CTD |
PMID:36863559 |
|
NCBI chr11:98,084,049...98,135,663
|
|
G |
Dnmt1 |
DNA methyltransferase 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of DNMT1 mRNA; T-2 Toxin results in increased expression of DNMT1 protein |
CTD |
PMID:31279042 |
|
NCBI chr 8:19,440,611...19,486,659
|
|
G |
Dnmt3a |
DNA methyltransferase 3 alpha |
increases expression |
EXP |
T-2 Toxin results in increased expression of DNMT3A mRNA; T-2 Toxin results in increased expression of DNMT3A protein |
CTD |
PMID:31279042 |
|
NCBI chr 6:32,507,316...32,621,678
|
|
G |
Dok3 |
docking protein 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of DOK3 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr17:9,109,633...9,115,188
|
|
G |
Dph1 |
diphthamide biosynthesis 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of DPH1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:60,028,081...60,039,764
|
|
G |
Dpy19l1 |
dpy-19 like C-mannosyltransferase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of DPY19L1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:22,933,163...23,021,461
|
|
G |
Dstn |
destrin, actin depolymerizing factor |
affects expression |
EXP |
T-2 Toxin affects the expression of DSTN protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:151,737,711...151,764,752
|
|
G |
Dusp1 |
dual specificity phosphatase 1 |
decreases expression increases expression |
EXP ISO |
T-2 Toxin results in decreased expression of DUSP1 mRNA T-2 Toxin results in increased expression of DUSP1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr10:17,184,853...17,187,646
|
|
G |
Dynll1 |
dynein light chain LC8-type 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of DYNLL1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:46,945,291...46,976,867
|
|
G |
Ecm2 |
extracellular matrix protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ECM2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr17:15,120,194...15,152,536
|
|
G |
Eef1d |
eukaryotic translation elongation factor 1 delta |
affects expression |
EXP |
T-2 Toxin affects the expression of EEF1D protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:109,462,645...109,478,021
|
|
G |
Eef1g |
eukaryotic translation elongation factor 1 gamma |
affects expression |
EXP |
T-2 Toxin affects the expression of EEF1G protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:205,860,713...205,871,319
|
|
G |
Eef2 |
eukaryotic translation elongation factor 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of EEF2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:9,183,836...9,196,255
|
|
G |
Eeig1 |
estrogen-induced osteoclastogenesis regulator 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EEIG1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:15,822,441...15,854,651
|
|
G |
Efhd1 |
EF-hand domain family, member D1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EFHD1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 9:95,386,155...95,432,800
|
|
G |
Egf |
epidermal growth factor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EGF mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:220,893,660...220,976,331
|
|
G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF2AK2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:21,941,147...21,977,115
|
|
G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
decreases expression increases phosphorylation |
ISO |
T-2 Toxin results in decreased expression of EIF2AK3 mRNA T-2 Toxin results in increased phosphorylation of EIF2AK3 protein |
CTD |
PMID:31863870 PMID:34673134 |
|
NCBI chr 4:104,363,838...104,425,271
|
|
G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
EXP ISO |
T-2 Toxin results in increased phosphorylation of EIF2S1 protein Selenomethionine inhibits the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein] salubrinal promotes the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:29454614 PMID:34673134 |
|
NCBI chr 6:103,405,880...103,430,549
|
|
G |
Eif3d |
eukaryotic translation initiation factor 3, subunit D |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF3D mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:109,539,795...109,552,184
|
|
G |
Eif3g |
eukaryotic translation initiation factor 3, subunit G |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF3G mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:19,429,728...19,433,760
|
|
G |
Eif3i |
eukaryotic translation initiation factor 3, subunit I |
affects expression |
EXP |
T-2 Toxin affects the expression of EIF3I protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:147,219,457...147,226,910
|
|
G |
Eif3j |
eukaryotic translation initiation factor 3, subunit J |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF3J mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:108,985,103...109,007,341
|
|
G |
Eif4a2 |
eukaryotic translation initiation factor 4A2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of EIF4A2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr11:91,268,730...91,276,738
|
|
G |
Eif5a |
eukaryotic translation initiation factor 5A |
affects expression |
EXP |
T-2 Toxin affects the expression of EIF5A protein |
CTD |
PMID:26141394 |
|
NCBI chr10:55,138,821...55,143,272
|
|
G |
Eif6 |
eukaryotic translation initiation factor 6 |
affects expression |
EXP |
T-2 Toxin affects the expression of EIF6 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:144,325,038...144,331,396
|
|
G |
Eloc |
elongin C |
affects expression |
EXP |
T-2 Toxin affects the expression of ELOC protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:2,661,527...2,677,893
|
|
G |
Emg1 |
EMG1 N1-specific pseudouridine methyltransferase |
increases expression |
ISO |
T-2 Toxin results in increased expression of EMG1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:157,509,258...157,517,540
|
|
G |
Eno1 |
enolase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of ENO1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:160,719,951...160,731,337
|
|
G |
Eomes |
eomesodermin |
increases expression |
ISO |
T-2 Toxin results in increased expression of EOMES mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 8:127,059,215...127,067,070
|
|
G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions increases expression |
ISO |
BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 mRNA]; BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 protein] T-2 Toxin results in increased expression of EPAS1 mRNA; T-2 Toxin results in increased expression of EPAS1 protein |
CTD |
PMID:22800716 PMID:34581912 |
|
NCBI chr 6:13,543,252...13,626,147
|
|
G |
Epb41l2 |
erythrocyte membrane protein band 4.1-like 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EPB41L2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:19,863,010...20,037,795
|
|
G |
Epb42 |
erythrocyte membrane protein band 4.2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of EPB42 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:107,979,709...107,997,932
|
|
G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EPRS1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:99,431,955...99,503,510
|
|
G |
Epyc |
epiphycan |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of EPYC mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:32,436,620...32,474,326
|
|
G |
Ereg |
epiregulin |
multiple interactions |
ISO |
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA] |
CTD |
PMID:30951242 |
|
NCBI chr14:17,311,485...17,325,260
|
|
G |
Ergic2 |
ERGIC and golgi 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ERGIC2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:181,090,808...181,123,074
|
|
G |
Ermp1 |
endoplasmic reticulum metallopeptidase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ERMP1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:227,383,992...227,422,120
|
|
G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of ERN1 protein ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein] |
CTD |
PMID:31170431 |
|
NCBI chr10:91,826,663...91,920,976
|
|
G |
Ern2 |
endoplasmic reticulum to nucleus signaling 2 |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of ERN2 protein ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein] |
CTD |
PMID:31170431 |
|
NCBI chr 1:186,153,115...186,174,521
|
|
G |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of ERO1A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr15:18,495,037...18,530,440
|
|
G |
Erp29 |
endoplasmic reticulum protein 29 |
affects expression |
EXP |
T-2 Toxin affects the expression of ERP29 protein |
CTD |
PMID:26141394 |
|
NCBI chr12:40,750,177...40,756,607
|
|
G |
Esrra |
estrogen related receptor, alpha |
affects expression |
EXP |
T-2 Toxin affects the expression of ESRRA mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:204,104,100...204,114,182
|
|
G |
Exosc2 |
exosome component 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of EXOSC2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:14,962,930...14,973,645
|
|
G |
Ezr |
ezrin |
affects expression |
EXP |
T-2 Toxin affects the expression of EZR protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:49,373,033...49,416,573
|
|
G |
Fam162a |
family with sequence similarity 162, member A |
increases expression |
ISO |
T-2 Toxin results in increased expression of FAM162A mRNA |
CTD |
PMID:31863870 |
|
NCBI chr11:78,186,260...78,215,186
|
|
G |
Fam216a |
family with sequence similarity 216, member A |
increases expression |
ISO |
T-2 Toxin results in increased expression of FAM216A mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:34,198,526...34,207,673
|
|
G |
Fanci |
FA complementation group I |
increases expression |
EXP |
T-2 Toxin results in increased expression of FANCI mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:142,736,636...142,792,999
|
|
G |
Fbxo2 |
F-box protein 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of FBXO2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:163,876,079...163,881,508
|
|
G |
Fbxo22 |
F-box protein 22 |
increases expression |
ISO |
T-2 Toxin results in increased expression of FBXO22 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:64,476,034...64,492,063
|
|
G |
Fbxo31 |
F-box protein 31 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to FBXO31] |
CTD |
PMID:36863559 |
|
NCBI chr19:49,624,813...49,656,052
|
|
G |
Fbxw4 |
F-box and WD repeat domain containing 4 |
increases expression |
EXP |
T-2 Toxin results in increased expression of FBXW4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:254,375,921...254,465,173
|
|
G |
Fcgr2b |
Fc gamma receptor 2B |
increases expression |
EXP |
T-2 Toxin results in increased expression of FCGR2B mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:85,725,897...85,740,517
|
|
G |
Fech |
ferrochelatase |
increases expression |
ISO |
T-2 Toxin results in increased expression of FECH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr18:57,945,123...57,978,327
|
|
G |
Fgf4 |
fibroblast growth factor 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of FGF4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:200,023,937...200,027,793
|
|
G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
EXP |
PINK1 promotes the reaction [T-2 Toxin results in increased expression of FIS1 mRNA] |
CTD |
PMID:36863559 |
|
NCBI chr12:25,345,239...25,360,135
|
|
G |
Fkbp4 |
FKBP prolyl isomerase 4 |
affects expression |
EXP |
T-2 Toxin affects the expression of FKBP4 protein |
CTD |
PMID:26141394 |
|
NCBI chr 4:163,389,464...163,397,918
|
|
G |
Fmod |
fibromodulin |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of FMOD mRNA |
CTD |
PMID:31863870 |
|
NCBI chr13:45,493,517...45,504,134
|
|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of FOSL2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 6:30,017,952...30,039,269
|
|
G |
Fscn1 |
fascin actin-bundling protein 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of FSCN1 protein |
CTD |
PMID:26141394 |
|
NCBI chr12:16,710,601...16,723,734
|
|
G |
Fshb |
follicle stimulating hormone subunit beta |
decreases expression multiple interactions |
EXP ISO |
T-2 Toxin results in decreased expression of FSHB protein 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Estradiol]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Progesterone] |
CTD |
PMID:26569305 PMID:30951242 |
|
NCBI chr 3:114,003,262...114,007,072
|
|
G |
Fubp1 |
far upstream element binding protein 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of FUBP1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 2:243,819,529...243,846,544
|
|
G |
Fuca1 |
alpha-L-fucosidase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of FUCA1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:148,152,718...148,169,972
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
affects expression decreases expression |
EXP |
T-2 Toxin affects the expression of G6PD protein T-2 Toxin results in decreased expression of G6PD mRNA |
CTD |
PMID:26141394 |
|
NCBI chr X:157,352,364...157,372,144
|
|
G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
increases expression decreases expression |
EXP ISO |
T-2 Toxin results in increased expression of GABBR1 mRNA T-2 Toxin results in decreased expression of GABBR1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr20:1,469,779...1,499,352
|
|
G |
Gabpa |
GA binding protein transcription factor subunit alpha |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of GABPA mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of COA5 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of DDX55 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF1 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF4 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS3 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS7 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of PEX5 mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFAM mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB1M mRNA]; GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB2M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to AFG1L]; T-2 Toxin promotes the reaction [GABPA protein binds to AR]; T-2 Toxin promotes the reaction [GABPA protein binds to COA5]; T-2 Toxin promotes the reaction [GABPA protein binds to DDX55]; T-2 Toxin promotes the reaction [GABPA protein binds to DISC1]; T-2 Toxin promotes the reaction [GABPA protein binds to DNM1L]; T-2 Toxin promotes the reaction [GABPA protein binds to FBXO31]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA12]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA1]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA9]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF1]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB2]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB3]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB5]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB7]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS3]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS7]; T-2 Toxin promotes the reaction [GABPA protein binds to NSFL1C]; T-2 Toxin promotes the reaction [GABPA protein binds to PARG]; T-2 Toxin promotes the reaction [GABPA protein binds to PEX5]; T-2 Toxin promotes the reaction [GABPA protein binds to TFAM]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB1M]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB2M]; T-2 Toxin promotes the reaction [GABPA protein binds to UQCRFS1]; T-2 Toxin promotes the reaction [GABPA protein binds to YARS2]; T-2 Toxin results in increased expression of and results in increased localization of GABPA protein |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr11:23,888,586...23,917,612
|
|
G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
EXP |
T-2 Toxin results in increased expression of GADD45G mRNA |
CTD |
PMID:26141394 |
|
NCBI chr17:13,528,606...13,530,351
|
|
G |
Gadd45gip1 |
GADD45G interacting protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GADD45GIP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr19:23,320,662...23,323,211
|
|
G |
Gal |
galanin and GMAP prepropeptide |
increases expression |
ISO |
T-2 Toxin results in increased expression of GAL mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:210,079,709...210,084,572
|
|
G |
Galnt1 |
polypeptide N-acetylgalactosaminyltransferase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GALNT1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr18:15,489,015...15,568,849
|
|
G |
Gan |
gigaxonin |
increases expression |
ISO |
T-2 Toxin results in increased expression of GAN mRNA |
CTD |
PMID:34581912 |
|
NCBI chr19:45,207,783...45,265,066
|
|
G |
Ganab |
glucosidase II alpha subunit |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GANAB protein |
CTD |
PMID:34581912 |
|
NCBI chr 1:215,222,918...215,242,808
|
|
G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
affects expression decreases expression |
EXP |
T-2 Toxin affects the expression of GAPDH protein T-2 Toxin results in decreased expression of GAPDH mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:157,962,312...157,967,158
|
|
G |
Gas6 |
growth arrest specific 6 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GAS6 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:82,747,676...82,778,090
|
|
G |
Gask1b |
golgi associated kinase 1B |
increases expression |
ISO |
T-2 Toxin results in increased expression of GASK1B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:165,047,689...165,112,479
|
|
G |
Gatb |
glutamyl-tRNA amidotransferase subunit B |
increases expression |
ISO |
T-2 Toxin results in increased expression of GATB mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:170,930,547...171,017,133
|
|
G |
Gatm |
glycine amidinotransferase |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GATM mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:109,658,919...109,675,508
|
|
G |
Gbe1 |
1,4-alpha-glucan branching enzyme 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GBE mRNA |
CTD |
PMID:34581912 |
|
NCBI chr11:8,734,806...9,000,226
|
|
G |
Gbp5 |
guanylate binding protein 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GBP5 mRNA |
CTD |
PMID:36775139 |
|
NCBI chr 2:231,237,748...231,257,071
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of GCLC mRNA T-2 Toxin results in increased expression of GCLC mRNA |
CTD |
PMID:20854872 PMID:33508416 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of GCLM mRNA T-2 Toxin results in increased expression of GCLM mRNA |
CTD |
PMID:20854872 PMID:33508416 |
|
NCBI chr 2:213,032,135...213,052,192
|
|
G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GDF15 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr16:18,838,436...18,842,022
|
|
G |
Gdf5 |
growth differentiation factor 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GDF5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:144,454,316...144,458,508
|
|
G |
Gdpd5 |
glycerophosphodiester phosphodiesterase domain containing 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GDPD5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:153,679,718...153,761,452
|
|
G |
Gfpt1 |
glutamine fructose-6-phosphate transaminase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GFPT1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:119,496,691...119,546,472
|
|
G |
Gh1 |
growth hormone 1 |
multiple interactions decreases expression |
EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; T-2 Toxin results in decreased expression of and results in decreased secretion of GH1 protein |
CTD |
PMID:26141394 PMID:29079362 |
|
NCBI chr10:91,727,883...91,729,860
|
|
G |
Ghitm |
growth hormone inducible transmembrane protein |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GHITM mRNA |
CTD |
PMID:26141394 |
|
NCBI chr16:12,885,551...12,897,887
|
|
G |
Ghrh |
growth hormone releasing hormone |
increases expression |
EXP |
T-2 Toxin results in increased expression of GHRH mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:145,992,762...146,012,528
|
|
G |
Gip |
gastric inhibitory polypeptide |
multiple interactions increases expression |
ISO |
T-2 Toxin results in increased expression of and results in increased secretion of GIP protein T-2 Toxin results in increased expression of GIP protein |
CTD |
PMID:28666375 PMID:29689362 |
|
NCBI chr10:81,465,070...81,473,216
|
|
G |
Glmp |
glycosylated lysosomal membrane protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GLMP mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:173,794,273...173,797,863
|
|
G |
Gnrh1 |
gonadotropin releasing hormone 1 |
decreases expression increases expression |
EXP |
T-2 Toxin results in decreased expression of GNRH1 mRNA T-2 Toxin results in increased expression of GNRH1 mRNA |
CTD |
PMID:26569305 PMID:26847343 |
|
NCBI chr15:41,972,482...41,976,690
|
|
G |
Gnrhr |
gonadotropin releasing hormone receptor |
increases expression |
EXP |
T-2 Toxin results in increased expression of GNRHR mRNA |
CTD |
PMID:26847343 |
|
NCBI chr14:21,856,871...21,874,861
|
|
G |
Gp6 |
glycoprotein VI |
increases expression |
ISO |
T-2 Toxin results in increased expression of GP6 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:78,471,900...78,535,374
|
|
G |
Gpatch4 |
G patch domain containing 4 |
increases expression |
ISO |
T-2 Toxin results in increased expression of GPATCH4 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:173,499,700...173,520,346
|
|
G |
Gpc4 |
glypican 4 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GPC4 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr X:131,644,711...131,755,349
|
|
G |
Gpr21 |
G protein-coupled receptor 21 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GPR21 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:21,275,289...21,279,008
|
|
G |
Gpr52 |
G protein-coupled receptor 52 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GPR52 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:72,800,265...72,804,989
|
|
G |
Gpsm2 |
G-protein signaling modulator 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GPSM2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:199,015,250...199,063,788
|
|
G |
Gpt |
glutamic--pyruvic transaminase |
increases activity |
ISO |
T-2 Toxin results in increased activity of GPT protein |
CTD |
PMID:23929680 |
|
NCBI chr 7:110,295,599...110,300,134
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
increases expression decreases expression decreases activity |
EXP ISO |
T-2 Toxin results in increased expression of GPX1 mRNA T-2 Toxin results in decreased expression of GPX1 mRNA T-2 Toxin results in decreased activity of GPX1 protein |
CTD |
PMID:26141394 PMID:27842451 PMID:29870751 PMID:30091165 |
|
NCBI chr 8:117,905,462...117,906,588
|
|
G |
Gpx2 |
glutathione peroxidase 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GPX2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:101,226,745...101,230,033
|
|
G |
Grb10 |
growth factor receptor bound protein 10 |
increases expression decreases expression |
EXP ISO |
T-2 Toxin results in increased expression of GRB10 mRNA T-2 Toxin results in decreased expression of GRB10 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr14:90,708,653...90,816,399
|
|
G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GRIA2 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 2:168,247,490...168,367,616
|
|
G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
increases expression |
ISO |
T-2 Toxin results in increased expression of GRIN2A mRNA |
CTD |
PMID:26314264 |
|
NCBI chr10:6,136,458...6,560,003
|
|
G |
Grm4 |
glutamate metabotropic receptor 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GRM4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr20:5,484,172...5,572,821
|
|
G |
Grn |
granulin precursor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of GRN mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:87,387,672...87,393,777
|
|
G |
Gsdma |
gasdermin A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of GSDMA mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:83,614,336...83,639,543
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases expression increases expression multiple interactions |
EXP ISO |
T-2 Toxin results in decreased expression of GSK3B mRNA T-2 Toxin results in increased expression of GSK3B protein 3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of GSK3B protein] |
CTD |
PMID:26141394 PMID:35289972 PMID:36402210 |
|
NCBI chr11:76,004,502...76,154,665
|
|
G |
Gsr |
glutathione-disulfide reductase |
decreases expression affects expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of GSR mRNA T-2 Toxin affects the expression of GSR mRNA T-2 Toxin affects the expression of and affects the activity of GSR protein |
CTD |
PMID:19526462 PMID:23929680 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Gss |
glutathione synthetase |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of GSS protein T-2 Toxin results in increased expression of GSS mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 3:144,047,849...144,078,197
|
|
G |
Gsto2 |
glutathione S-transferase omega 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of GSTO2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:246,731,314...246,757,592
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of GSTP1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:210,767,237...210,770,242
|
|
G |
Gstt2 |
glutathione S-transferase theta 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of GSTT2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr20:12,819,053...12,822,724
|
|
G |
H1f10 |
H1.10 linker histone |
increases expression |
EXP |
T-2 Toxin results in increased expression of H1F10 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:121,997,834...121,998,897
|
|
G |
H2ax |
H2A.X variant histone |
multiple interactions increases activity |
ISO |
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of H2AX protein] |
CTD |
PMID:20150440 |
|
NCBI chr 8:53,568,718...53,570,072
|
|
G |
H6pd |
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of H6PD mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 5:160,434,499...160,470,203
|
|
G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of HAPLN1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:20,631,640...20,696,388
|
|
G |
Has2 |
hyaluronan synthase 2 |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of HAS2 mRNA T-2 Toxin results in increased expression of HAS2 mRNA |
CTD |
PMID:18196609 PMID:31863870 |
|
NCBI chr 7:90,002,929...90,028,933
|
|
G |
Hbs1l |
HBS1-like translational GTPase |
increases expression |
ISO |
T-2 Toxin results in increased expression of HBS1L mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:16,092,529...16,170,082
|
|
G |
Hbz |
hemoglobin subunit zeta |
increases expression |
ISO |
T-2 Toxin results in increased expression of HBZ mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:15,848,279...15,849,757
|
|
G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
increases expression |
EXP |
T-2 Toxin results in increased expression of HCK mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:162,031,833...162,074,933
|
|
G |
Helq |
helicase, POLQ-like |
increases expression |
EXP |
T-2 Toxin results in increased expression of HELQ mRNA |
CTD |
PMID:26141394 |
|
NCBI chr14:8,818,582...8,862,926
|
|
G |
Hexim2 |
HEXIM P-TEFb complex subunit 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of HEXIM2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:88,077,870...88,084,776
|
|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression |
ISO |
T-2 Toxin results in increased expression of HIF1A protein |
CTD |
PMID:36115646 |
|
NCBI chr 6:98,357,788...98,405,068
|
|
G |
Hipk3 |
homeodomain interacting protein kinase 3 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of HIPK3 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:111,251,863...111,322,815
|
|
G |
Hist1h2bd |
histone cluster 1 H2B family member D |
increases expression |
ISO |
T-2 Toxin results in increased expression of H2BC5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr17:47,488,627...47,489,008
|
|
G |
Hmga1 |
high mobility group AT-hook 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of HMGA1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr20:5,611,088...5,618,755
|
|
G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of HMGCR mRNA |
CTD |
PMID:22982764 PMID:34581912 |
|
NCBI chr 2:29,732,163...29,754,276
|
|
G |
Hmox1 |
heme oxygenase 1 |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of HMOX1 mRNA; T-2 Toxin results in decreased expression of HMOX1 protein T-2 Toxin results in increased expression of HMOX1 mRNA |
CTD |
PMID:20854872 PMID:29432840 PMID:33508416 |
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPA2B1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 4:81,867,354...81,875,886
|
|
G |
Hnrnpa3 |
heterogeneous nuclear ribonucleoprotein A3 |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPA3 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:60,578,574...60,588,755
|
|
G |
Hnrnpab |
heterogeneous nuclear ribonucleoprotein A/B |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPAB protein |
CTD |
PMID:26141394 |
|
NCBI chr10:36,358,004...36,363,898
|
|
G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPH1 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:34,692,868...34,702,849
|
|
G |
Hnrnpk |
heterogeneous nuclear ribonucleoprotein K |
affects expression |
EXP |
T-2 Toxin affects the expression of HNRNPK protein |
CTD |
PMID:26141394 |
|
NCBI chr17:6,269,302...6,280,429
|
|
G |
Hp |
haptoglobin |
increases expression |
EXP |
T-2 Toxin results in increased expression of HP mRNA |
CTD |
PMID:26141394 |
|
NCBI chr19:54,449,151...54,453,701
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSP90AA1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 6:135,523,604...135,529,687
|
|
G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
affects expression decreases expression |
EXP |
T-2 Toxin affects the expression of HSP90AB1 protein T-2 Toxin results in decreased expression of HSP90AB1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 9:22,930,249...22,935,929
|
|
G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSP90B1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:22,997,962...23,012,293
|
|
G |
Hspa4 |
heat shock protein family A (Hsp70) member 4 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSPA4 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:37,908,866...37,951,994
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions affects expression increases expression |
ISO EXP |
salubrinal inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein]; T-2 Toxin results in increased degradation of and results in decreased expression of HSPA5 protein T-2 Toxin affects the expression of HSPA5 protein Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein] T-2 Toxin results in increased expression of HSPA5 mRNA; T-2 Toxin results in increased expression of HSPA5 protein |
CTD |
PMID:19336499 PMID:26141394 PMID:29454614 PMID:31170431 PMID:34673134 |
|
NCBI chr 3:38,453,016...38,457,475
|
|
G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSPA8 protein |
CTD |
PMID:26141394 |
|
NCBI chr 8:50,080,514...50,084,376
|
|
G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSPA9 protein |
CTD |
PMID:26141394 |
|
NCBI chr18:26,536,131...26,554,294
|
|
G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions increases expression |
ISO |
T-2 Toxin results in increased expression of and results in decreased phosphorylation of HSPB1 protein T-2 Toxin results in increased expression of HSPB1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:26,430,640...26,432,301
|
|
G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of HSPD1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 9:64,073,610...64,084,332
|
|
G |
Htra4 |
HtrA serine peptidase 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of HTRA4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr16:67,001,605...67,015,074
|
|
G |
Hus1 |
HUS1 checkpoint clamp component |
increases expression |
EXP |
T-2 Toxin results in increased expression of HUS1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr14:83,688,702...83,703,466
|
|
G |
Hyi |
hydroxypyruvate isomerase |
increases expression |
ISO |
T-2 Toxin results in increased expression of HYI mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:137,179,975...137,182,654
|
|
G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of ID2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 6:47,469,162...47,470,995
|
|
G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
decreases expression |
EXP ISO |
T-2 Toxin results in decreased expression of IDH1 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 9:66,534,146...66,563,703
|
|
G |
Idh3a |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
affects expression |
EXP |
T-2 Toxin affects the expression of IDH3A protein |
CTD |
PMID:26141394 |
|
NCBI chr 8:63,867,882...63,887,223
|
|
G |
Idh3b |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
increases expression |
ISO |
T-2 Toxin results in increased expression of IDH3B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:117,481,845...117,486,909
|
|
G |
Ier3 |
immediate early response 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IER3 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:2,933,173...2,934,377
|
|
G |
Ifitm10 |
interferon induced transmembrane protein 10 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of IFITM10 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:197,507,501...197,524,180
|
|
G |
Ifng |
interferon gamma |
increases expression |
ISO |
T-2 Toxin results in increased expression of IFNG protein |
CTD |
PMID:36115646 |
|
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IFRD1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:62,996,560...63,044,996
|
|
G |
Igf2bp2 |
insulin-like growth factor 2 mRNA binding protein 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IGF2BP2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr11:92,378,908...92,478,893
|
|
G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of IGFBP4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:84,491,471...84,503,487
|
|
G |
Igfbpl1 |
insulin-like growth factor binding protein-like 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IGFBPL1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 5:60,076,428...60,091,833
|
|
G |
Igflr1 |
IGF-like family receptor 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IGFLR1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:85,818,428...85,821,032
|
|
G |
Ikzf3 |
IKAROS family zinc finger 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IKZF3 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:83,460,564...83,553,591
|
|
G |
Il10 |
interleukin 10 |
affects expression decreases expression |
ISO |
T-2 Toxin affects the expression of IL10 mRNA T-2 Toxin results in decreased expression of IL10 mRNA; T-2 Toxin results in decreased expression of IL10 protein |
CTD |
PMID:22960706 PMID:31170431 |
|
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il11 |
interleukin 11 |
increases expression multiple interactions decreases methylation |
EXP |
T-2 Toxin results in increased expression of IL11 mRNA; T-2 Toxin results in increased expression of IL11 protein Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of IL11 promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL11 mRNA] |
CTD |
PMID:29079362 PMID:31279042 |
|
NCBI chr 1:69,069,829...69,076,129
|
|
G |
Il1a |
interleukin 1 alpha |
increases expression decreases methylation |
ISO EXP |
T-2 Toxin results in increased expression of IL1A mRNA T-2 Toxin results in decreased methylation of IL1A promoter |
CTD |
PMID:21112371 PMID:31279042 PMID:36775139 |
|
NCBI chr 3:136,979,804...136,990,236
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; SB 203580 inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; Selenium promotes the reaction [T-2 Toxin results in increased expression of IL1B protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein] T-2 Toxin results in increased expression of IL1B mRNA; T-2 Toxin results in increased expression of IL1B protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA] |
CTD |
PMID:18196609 PMID:21112371 PMID:21453744 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 PMID:31279042 PMID:32240701 PMID:36775139 More...
|
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il2 |
interleukin 2 |
affects secretion increases expression |
ISO |
T-2 Toxin affects the secretion of IL2 protein T-2 Toxin results in increased expression of IL2 mRNA |
CTD |
PMID:8560498 |
|
NCBI chr 2:121,932,968...121,937,672
|
|
G |
Il20rb |
interleukin 20 receptor subunit beta |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of IL20RB mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:100,979,085...101,010,829
|
|
G |
Il22 |
interleukin 22 |
increases expression |
EXP |
T-2 Toxin results in increased expression of IL22 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:53,801,206...53,805,673
|
|
G |
Il4 |
interleukin 4 |
affects secretion decreases expression |
ISO |
T-2 Toxin affects the secretion of IL4 protein T-2 Toxin results in decreased expression of IL4 mRNA |
CTD |
PMID:8560498 PMID:22960706 |
|
NCBI chr10:38,272,003...38,277,549
|
|
G |
Il5 |
interleukin 5 |
affects secretion |
ISO |
T-2 Toxin affects the secretion of IL5 protein |
CTD |
PMID:8560498 |
|
NCBI chr10:38,375,132...38,378,003
|
|
G |
Il6 |
interleukin 6 |
multiple interactions increases expression affects expression decreases methylation |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA] T-2 Toxin results in increased expression of IL6 mRNA; T-2 Toxin results in increased expression of IL6 protein AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 protein] T-2 Toxin affects the expression of IL6 mRNA T-2 Toxin results in decreased methylation of IL6 promoter |
CTD |
PMID:21112371 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 PMID:31279042 PMID:32240701 PMID:36775139 More...
|
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Imp4 |
IMP U3 small nucleolar ribonucleoprotein 4 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IMP4 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 9:36,654,127...36,659,265
|
|
G |
Insig1 |
insulin induced gene 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of INSIG1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:8,049,339...8,057,812
|
|
G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IRAK1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr X:156,919,927...156,929,825
|
|
G |
Irak2 |
interleukin-1 receptor-associated kinase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of IRAK2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:148,341,704...148,398,211
|
|
G |
Islr |
immunoglobulin superfamily containing leucine-rich repeat |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ISLR mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:67,467,013...67,469,989
|
|
G |
Itga10 |
integrin subunit alpha 10 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGA10 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:184,182,869...184,202,172
|
|
G |
Itga11 |
integrin subunit alpha 11 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGA11 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:63,145,998...63,254,714
|
|
G |
Itgam |
integrin subunit alpha M |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of ITGAM protein Minocycline inhibits the reaction [T-2 Toxin results in increased expression of ITGAM protein] |
CTD |
PMID:36775139 |
|
NCBI chr 1:192,089,496...192,139,947
|
|
G |
Itgb1 |
integrin subunit beta 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGB1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr19:73,602,277...73,650,271
|
|
G |
Itgb5 |
integrin subunit beta 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGB5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr11:66,828,428...66,944,231
|
|
G |
Itgbl1 |
integrin subunit beta like 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of ITGBL1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr15:100,780,184...101,041,734
|
|
G |
Jag1 |
jagged canonical Notch ligand 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of JAG1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:124,406,783...124,442,220
|
|
G |
Jag2 |
jagged canonical Notch ligand 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of JAG2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 6:131,983,059...132,005,665
|
|
G |
Jak1 |
Janus kinase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of JAK1 mRNA |
CTD |
PMID:22454431 |
|
NCBI chr 5:120,895,606...121,004,207
|
|
G |
Jak2 |
Janus kinase 2 |
multiple interactions increases expression decreases expression |
ISO |
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA] T-2 Toxin results in decreased expression of JAK2 mRNA |
CTD |
PMID:22454431 PMID:34581912 |
|
NCBI chr 1:236,408,905...236,468,769
|
|
G |
Jam3 |
junctional adhesion molecule 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of JAM3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:25,508,461...25,569,306
|
|
G |
Jdp2 |
Jun dimerization protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of JDP2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 6:110,988,927...111,033,392
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP ISO |
T-2 Toxin results in increased expression of JUN mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Kcnc3 |
potassium voltage-gated channel subfamily C member 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of KCNC3 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:95,080,960...95,095,165
|
|
G |
Kcnma1 |
potassium calcium-activated channel subfamily M alpha 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of KCNMA1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr15:302,480...1,007,675
|
|
G |
Kdelr2 |
KDEL endoplasmic reticulum protein retention receptor 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KDELR2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr12:11,138,820...11,157,117
|
|
G |
Kdelr3 |
KDEL endoplasmic reticulum protein retention receptor 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KDELR3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:112,959,632...112,969,858
|
|
G |
Kdm4d |
lysine demethylase 4D |
increases expression |
ISO |
T-2 Toxin results in increased expression of KDM4D mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:11,279,756...11,304,920
|
|
G |
Keap1 |
Kelch-like ECH-associated protein 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KEAP1 mRNA; T-2 Toxin results in decreased expression of KEAP1 protein |
CTD |
PMID:35842139 |
|
NCBI chr 8:19,768,375...19,777,862
|
|
G |
Kiaa0232 |
KIAA0232 homolog |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KIAA0232 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr14:74,094,421...74,159,316
|
|
G |
Kif16b |
kinesin family member 16B |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of KIF16B mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:129,974,692...130,254,194
|
|
G |
Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression |
ISO |
T-2 Toxin results in increased expression of KIT mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:32,901,615...32,978,895
|
|
G |
Kitlg |
KIT ligand |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of KITLG mRNA; T-2 Toxin results in decreased expression of KITLG protein |
CTD |
PMID:26314264 |
|
NCBI chr 7:36,782,621...36,863,796
|
|
G |
Klf6 |
KLF transcription factor 6 |
increases expression |
ISO |
T-2 Toxin results in increased expression of KLF6 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr17:69,449,483...69,458,478
|
|
G |
Krt1 |
keratin 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of KRT1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:132,976,618...132,981,844
|
|
G |
Krt8 |
keratin 8 |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of KRT8 protein T-2 Toxin results in increased expression of KRT8 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 7:135,002,886...135,010,339
|
|
G |
Lama5 |
laminin subunit alpha 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of LAMA5 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:167,270,296...167,318,370
|
|
G |
Lars1 |
leucyl-tRNA synthetase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of LARS1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr18:34,452,567...34,507,030
|
|
G |
Lbh |
LBH regulator of WNT signaling pathway |
increases expression |
ISO |
T-2 Toxin results in increased expression of LBH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 6:28,321,040...28,344,855
|
|
G |
Lcp2 |
lymphocyte cytosolic protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of LCP2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:19,146,846...19,193,750
|
|
G |
Ldha |
lactate dehydrogenase A |
increases expression |
ISO |
T-2 Toxin results in increased expression of LDHA protein |
CTD |
PMID:36115646 |
|
NCBI chr 1:97,371,823...97,381,247
|
|
G |
Lgals1 |
galectin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of LGALS1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:112,365,695...112,368,801
|
|
G |
Lgr5 |
leucine rich repeat containing G protein coupled receptor 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of LGR5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:52,973,151...53,107,964
|
|
G |
Lhb |
luteinizing hormone subunit beta |
decreases expression increases secretion |
EXP |
T-2 Toxin results in decreased expression of LHB protein T-2 Toxin results in increased secretion of LHB protein |
CTD |
PMID:26569305 PMID:26847343 |
|
NCBI chr 1:105,037,457...105,038,446
|
|
G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
multiple interactions |
ISO |
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA] |
CTD |
PMID:30951242 |
|
NCBI chr 6:5,661,871...5,728,109
|
|
G |
Lin28a |
lin-28 homolog A |
increases expression |
ISO |
T-2 Toxin results in increased expression of LIN28A mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 5:146,227,119...146,244,122
|
|
G |
LOC100909998 |
zinc finger protein 2-like |
increases expression |
ISO |
T-2 Toxin results in increased expression of ZNF2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:114,793,783...114,818,395
|
|
G |
Lrpap1 |
LDL receptor related protein associated protein 1 |
affects expression decreases expression |
EXP ISO |
T-2 Toxin affects the expression of LRPAP1 protein T-2 Toxin results in decreased expression of LRPAP1 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
|
NCBI chr14:75,651,371...75,663,380
|
|
G |
Ltbp2 |
latent transforming growth factor beta binding protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of LTBP2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 6:110,161,029...110,261,586
|
|
G |
Lyz2 |
lysozyme 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of LYZ mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 7:52,906,810...52,912,154
|
|
G |
Macf1 |
microtubule-actin crosslinking factor 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MACF1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 5:140,908,829...141,234,127
|
|
G |
Map1b |
microtubule-associated protein 1B |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MAP1B mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:32,551,423...32,644,471
|
|
G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression multiple interactions affects expression |
EXP ISO |
T-2 Toxin results in increased expression of MAP1LC3B mRNA T-2 Toxin results in increased expression of and results in increased cleavage of MAP1LC3B protein T-2 Toxin affects the expression of MAP1LC3B protein 3-methyladenine affects the reaction [T-2 Toxin affects the expression of MAP1LC3B protein] |
CTD |
PMID:29413859 PMID:36402210 |
|
NCBI chr19:66,571,631...66,582,270
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation |
ISO |
T-2 Toxin results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:36775139 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
T-2 Toxin results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:36775139 |
|
NCBI chr16:8,645,171...8,728,225
|
|
G |
Mapk8ip1 |
mitogen-activated protein kinase 8 interacting protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MAPK8IP1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:98,810,540...98,829,302
|
|
G |
Mars2 |
methionyl-tRNA synthetase 2, mitochondrial |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of MARS2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 9:64,214,935...64,228,408
|
|
G |
Mat2a |
methionine adenosyltransferase 2A |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MAT2A mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:106,048,043...106,053,612
|
|
G |
Mbtps1 |
membrane-bound transcription factor peptidase, site 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MBTPS1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr19:47,561,598...47,612,769
|
|
G |
Mcf2l |
MCF.2 cell line derived transforming sequence-like |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of MCF2L mRNA |
CTD |
PMID:26141394 |
|
NCBI chr16:76,507,133...76,652,893
|
|
G |
Mcm7 |
minichromosome maintenance complex component 7 |
affects expression |
EXP |
T-2 Toxin affects the expression of MCM7 protein |
CTD |
PMID:26141394 |
|
NCBI chr12:22,155,921...22,163,320
|
|
G |
Mdh1 |
malate dehydrogenase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of MDH1 protein |
CTD |
PMID:26141394 |
|
NCBI chr14:95,630,625...95,645,920
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
increases expression |
EXP ISO |
T-2 Toxin results in increased expression of MDM2 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
|
NCBI chr 7:55,176,558...55,201,757
|
|
G |
Megf6 |
multiple EGF-like-domains 6 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MEGF6 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:170,020,699...170,121,557
|
|
G |
Meltf |
melanotransferrin |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MELTF mRNA |
CTD |
PMID:31863870 |
|
NCBI chr11:68,884,446...68,906,300
|
|
G |
Mesd |
mesoderm development LRP chaperone |
affects expression |
EXP |
T-2 Toxin affects the expression of MESD protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:137,866,707...137,879,999
|
|
G |
Metrnl |
meteorin-like, glial cell differentiation regulator |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of METRNL mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:106,963,880...106,977,875
|
|
G |
Mettl9 |
methyltransferase 9, His-X-His N1(pi)-histidine |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of METTL9 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:175,575,805...175,623,065
|
|
G |
Mfge8 |
milk fat globule EGF and factor V/VIII domain containing |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MFGE8 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:142,474,027...142,489,431
|
|
G |
Mfn1 |
mitofusin 1 |
multiple interactions |
EXP |
PINK1 promotes the reaction [T-2 Toxin results in increased expression of MFN1 mRNA] |
CTD |
PMID:36863559 |
|
NCBI chr 2:115,313,380...115,359,651
|
|
G |
Mir155 |
microRNA 155 |
multiple interactions increases expression |
ISO |
MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA] T-2 Toxin results in increased expression of MIR155 mRNA |
CTD |
PMID:32240701 |
|
NCBI chr11:37,261,114...37,261,178
|
|
G |
Mknk2 |
MAPK interacting serine/threonine kinase 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MKNK2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:9,690,385...9,701,527
|
|
G |
Mmd |
monocyte to macrophage differentiation-associated |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of MMD mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:75,570,366...75,598,610
|
|
G |
Mmp1 |
matrix metallopeptidase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MMP1 protein |
CTD |
PMID:21144892 |
|
NCBI chr 8:12,943,453...12,963,966
|
|
G |
Mmp12 |
matrix metallopeptidase 12 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MMP12 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr 8:4,581,785...4,591,687
|
|
G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions increases expression |
ISO EXP |
4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein] T-2 Toxin results in increased expression of MMP13 mRNA; T-2 Toxin results in increased expression of MMP13 protein [salubrinal co-treated with T-2 Toxin] results in increased expression of MMP13 mRNA; salubrinal inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein] |
CTD |
PMID:21144892 PMID:22800716 PMID:34673134 PMID:35213812 |
|
NCBI chr 8:4,497,960...4,508,239
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
increases activity decreases expression |
ISO |
T-2 Toxin results in increased activity of MMP2 protein T-2 Toxin results in decreased expression of MMP2 mRNA |
CTD |
PMID:21112371 PMID:22960706 |
|
NCBI chr19:30,327,643...30,355,856
|
|
G |
Mmp3 |
matrix metallopeptidase 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MMP3 mRNA |
CTD |
PMID:22800716 |
|
NCBI chr 8:12,925,267...12,938,828
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
affects expression increases activity multiple interactions increases expression |
ISO EXP |
T-2 Toxin affects the expression of MMP9 mRNA T-2 Toxin results in increased activity of MMP9 protein T-2 Toxin results in increased expression of and results in increased activity of MMP9 protein T-2 Toxin results in increased expression of MMP9 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA] |
CTD |
PMID:21112371 PMID:22800716 PMID:22960706 PMID:29079362 |
|
NCBI chr 3:174,103,474...174,111,434
|
|
G |
Mpdu1 |
mannose-P-dolichol utilization defect 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MPDU1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:54,374,719...54,380,301
|
|
G |
Mphosph9 |
M-phase phosphoprotein 9 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MPHOSPH9 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:32,275,449...32,346,097
|
|
G |
Mpo |
myeloperoxidase |
increases activity |
ISO |
T-2 Toxin results in increased activity of MPO protein |
CTD |
PMID:22960706 |
|
NCBI chr10:73,092,124...73,102,057
|
|
G |
Mpst |
mercaptopyruvate sulfurtransferase |
affects expression |
EXP |
T-2 Toxin affects the expression of MPST protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:111,836,079...111,843,651
|
|
G |
Mrap2 |
melanocortin 2 receptor accessory protein 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MRAP2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:96,968,239...97,024,581
|
|
G |
Mre11 |
MRE11 homolog, double strand break repair nuclease |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MRE11A mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:19,900,211...19,961,906
|
|
G |
Mrpl58 |
mitochondrial ribosomal protein L58 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MRPL58 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:100,646,374...100,652,871
|
|
G |
Mrps18c |
mitochondrial ribosomal protein S18C |
increases expression |
ISO |
T-2 Toxin results in increased expression of MRPS18C mRNA |
CTD |
PMID:31863870 |
|
NCBI chr14:9,116,688...9,122,943
|
|
G |
Mrps22 |
mitochondrial ribosomal protein S22 |
increases expression |
ISO |
T-2 Toxin results in increased expression of MRPS22 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:99,184,110...99,197,278
|
|
G |
Ms4a3 |
membrane spanning 4-domains A3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MS4A3 mRNA; T-2 Toxin results in decreased expression of MS4A3 protein |
CTD |
PMID:34581912 |
|
NCBI chr 1:208,462,300...208,480,129
|
|
G |
Msmo1 |
methylsterol monooxygenase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MSMO1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr16:24,980,680...24,997,927
|
|
G |
Mt-atp6 |
mitochondrially encoded ATP synthase membrane subunit 6 |
affects expression |
EXP |
T-2 Toxin affects the expression of ATP6 mRNA |
CTD |
PMID:29870751 |
|
|
|
G |
Mt-atp8 |
mitochondrially encoded ATP synthase membrane subunit 8 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ATP8 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961 NCBI chr MT:7,758...7,961
|
|
G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
increases expression |
EXP |
T-2 Toxin results in increased expression of COX1 mRNA |
CTD |
PMID:29870751 |
|
|
|
G |
Mt-co2 |
mitochondrially encoded cytochrome c oxidase II |
increases expression |
EXP |
T-2 Toxin results in increased expression of COX2 mRNA |
CTD |
PMID:29870751 |
|
|
|
G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
increases expression |
EXP |
T-2 Toxin results in increased expression of COX3 mRNA |
CTD |
PMID:29870751 |
|
|
|
G |
Mt-cyb |
mitochondrially encoded cytochrome b |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of CYTB mRNA |
CTD |
PMID:29870751 |
|
NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278 NCBI chr MT:14,136...15,278
|
|
G |
Mt-nd3 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ND3 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798 NCBI chr MT:9,451...9,798
|
|
G |
Mt-nd5 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ND5 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565 NCBI chr MT:11,736...13,565
|
|
G |
Mt-nd6 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 |
increases expression |
EXP |
T-2 Toxin results in increased expression of ND6 mRNA |
CTD |
PMID:29870751 |
|
|
|
G |
Mthfd2 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
decreases expression |
EXP ISO |
T-2 Toxin results in decreased expression of MTHFD2 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
|
NCBI chr 4:115,811,135...115,822,663
|
|
G |
Mtor |
mechanistic target of rapamycin kinase |
affects expression |
EXP |
T-2 Toxin affects the expression of MTOR protein |
CTD |
PMID:29413859 |
|
NCBI chr 5:164,167,985...164,277,438
|
|
G |
Mtpn |
myotrophin |
affects expression |
EXP |
T-2 Toxin affects the expression of MTPN protein |
CTD |
PMID:26141394 |
|
NCBI chr 4:64,159,273...64,186,686
|
|
G |
Muc2 |
mucin 2, oligomeric mucus/gel-forming |
multiple interactions decreases expression |
ISO |
ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein] |
CTD |
PMID:31170431 |
|
NCBI chr 1:206,225,775...206,261,280
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of MYC mRNA |
CTD |
PMID:35289972 |
|
NCBI chr 7:95,483,105...95,488,031
|
|
G |
Nanos1 |
nanos C2HC-type zinc finger 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NANOS1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:259,897,663...259,901,561
|
|
G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of NARS1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr18:57,989,308...58,005,584
|
|
G |
Ndufa1 |
NADH:ubiquinone oxidoreductase subunit A1 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA1] |
CTD |
PMID:36863559 |
|
NCBI chr X:121,289,904...121,293,555
|
|
G |
Ndufa12 |
NADH:ubiquinone oxidoreductase subunit A12 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA12] |
CTD |
PMID:36863559 |
|
NCBI chr 7:28,771,330...28,798,316
|
|
G |
Ndufa4 |
Ndufa4, mitochondrial complex associated |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA4] |
CTD |
PMID:36863559 |
|
NCBI chr 4:40,968,391...40,975,559
|
|
G |
Ndufa9 |
NADH:ubiquinone oxidoreductase subunit A9 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFA9] |
CTD |
PMID:36863559 |
|
NCBI chr 4:161,345,398...161,374,188
|
|
G |
Ndufaf1 |
NADH:ubiquinone oxidoreductase complex assembly factor 1 |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of NDUFAF1 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF1 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF1] |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr 3:106,639,025...106,650,549
|
|
G |
Ndufaf2 |
NADH:ubiquinone oxidoreductase complex assembly factor 2 |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of NDUFAF2 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2] |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr 2:39,535,680...39,647,378
|
|
G |
Ndufaf3 |
NADH:ubiquinone oxidoreductase complex assembly factor 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFAF3 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 8:109,261,362...109,263,194
|
|
G |
Ndufaf4 |
NADH:ubiquinone oxidoreductase complex assembly factor 4 |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of NDUFAF4 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF4 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF4] |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr 5:38,605,169...38,610,341
|
|
G |
Ndufb2 |
NADH:ubiquinone oxidoreductase subunit B2 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB2] |
CTD |
PMID:36863559 |
|
NCBI chr 4:69,334,307...69,341,394
|
|
G |
Ndufb3 |
NADH:ubiquinone oxidoreductase subunit B3 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB3] |
CTD |
PMID:36863559 |
|
NCBI chr 9:60,129,240...60,139,452
|
|
G |
Ndufb4 |
NADH:ubiquinone oxidoreductase subunit B4 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB4] |
CTD |
PMID:36863559 |
|
NCBI chr11:76,569,178...76,575,879
|
|
G |
Ndufb5 |
NADH:ubiquinone oxidoreductase subunit B5 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB5] |
CTD |
PMID:36863559 |
|
NCBI chr 2:115,519,248...115,533,589
|
|
G |
Ndufb7 |
NADH:ubiquinone oxidoreductase subunit B7 |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NDUFB7] |
CTD |
PMID:36863559 |
|
NCBI chr19:24,568,241...24,572,579
|
|
G |
Ndufs1 |
NADH:ubiquinone oxidoreductase core subunit S1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFS1 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 9:64,546,430...64,579,751
|
|
G |
Ndufs3 |
NADH:ubiquinone oxidoreductase core subunit S3 |
affects expression increases expression multiple interactions |
EXP |
T-2 Toxin affects the expression of NDUFS3 protein T-2 Toxin results in increased expression of NDUFS3 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS3 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS3] |
CTD |
PMID:26141394 PMID:29870751 PMID:36863559 |
|
NCBI chr 3:76,876,646...76,883,824
|
|
G |
Ndufs4 |
NADH:ubiquinone oxidoreductase subunit S4 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFS4 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 2:47,684,420...47,794,914
|
|
G |
Ndufs5 |
NADH:ubiquinone oxidoreductase subunit S5 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of NDUFS5 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 5:141,258,828...141,264,552
|
|
G |
Ndufs6 |
NADH:ubiquinone oxidoreductase subunit S6 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFS6 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:31,797,400...31,805,965
|
|
G |
Ndufs7 |
NADH:ubiquinone oxidoreductase core subunit S7 |
increases expression multiple interactions |
EXP |
T-2 Toxin results in increased expression of NDUFS7 mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFS7 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFS7] |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr 7:9,452,556...9,460,135
|
|
G |
Ndufs8 |
NADH:ubiquinone oxidoreductase core subunit S8 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFS8 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:201,140,585...201,144,573
|
|
G |
Ndufv1 |
NADH:ubiquinone oxidoreductase core subunit V1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFV1 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:201,300,365...201,305,461
|
|
G |
Ndufv2 |
NADH:ubiquinone oxidoreductase core subunit V2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFV2 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 9:113,137,305...113,157,571
|
|
G |
Ndufv3 |
NADH:ubiquinone oxidoreductase subunit V3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NDUFV3 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr20:9,613,786...9,622,941
|
|
G |
Nefh |
neurofilament heavy chain |
increases expression |
ISO |
T-2 Toxin results in increased expression of NEFH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:84,044,428...84,054,413
|
|
G |
Nelfe |
negative elongation factor complex member E |
increases expression |
ISO |
T-2 Toxin results in increased expression of NELFE mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:3,976,512...3,982,389
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
decreases expression increases expression multiple interactions |
ISO EXP |
T-2 Toxin results in decreased expression of NFE2L2 mRNA; T-2 Toxin results in decreased expression of NFE2L2 protein T-2 Toxin results in increased expression of NFE2L2 protein N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein] T-2 Toxin results in increased expression of NFE2L2 mRNA; T-2 Toxin results in increased expression of NFE2L2 protein NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM protein] |
CTD |
PMID:20854872 PMID:29432840 PMID:29870751 PMID:33508416 PMID:35842139 |
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions increases phosphorylation |
ISO |
BAY 11-7085 inhibits the reaction [T-2 Toxin results in decreased expression of and results in increased degradation of NFKBIA protein]; T-2 Toxin results in increased degradation of and results in decreased expression of NFKBIA protein T-2 Toxin results in increased phosphorylation of NFKBIA protein |
CTD |
PMID:22800716 PMID:36775139 |
|
NCBI chr 6:78,593,844...78,597,307
|
|
G |
Nfkbil1 |
NFKB inhibitor like 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NFKBIL1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr20:3,589,974...3,608,348
|
|
G |
Nfrkb |
nuclear factor related to kappa B binding protein |
increases expression |
EXP |
T-2 Toxin results in increased expression of NFRKB mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:38,089,574...38,121,506
|
|
G |
Nhej1 |
nonhomologous end-joining factor 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NHEJ1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 9:76,526,322...76,622,488
|
|
G |
Niban1 |
niban apoptosis regulator 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NIBAN1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr13:63,674,240...63,827,748
|
|
G |
Nme2 |
NME/NM23 nucleoside diphosphate kinase 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of NME2 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:79,394,999...79,400,418
|
|
G |
Nol9 |
nucleolar protein 9 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOL9 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:167,829,249...167,849,364
|
|
G |
Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOLC1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:244,921,275...244,932,089
|
|
G |
Nop14 |
NOP14 nucleolar protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOP14 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:76,081,313...76,102,454
|
|
G |
Nop2 |
NOP2 nucleolar protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOP2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 4:157,932,731...157,944,462
|
|
G |
Nos2 |
nitric oxide synthase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NOS2 mRNA |
CTD |
PMID:21112371 PMID:22960706 PMID:36775139 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
Nos3 |
nitric oxide synthase 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NOS3 mRNA |
CTD |
PMID:22960706 |
|
NCBI chr 4:11,686,088...11,706,604
|
|
G |
Notch1 |
notch receptor 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NOTCH1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:29,676,040...29,721,613
|
|
G |
Npm1 |
nucleophosmin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of NPM1 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:17,741,512...17,751,626
|
|
G |
Nptxr |
neuronal pentraxin receptor |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of NPTXR mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:111,336,660...111,354,737
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
decreases expression increases expression |
ISO EXP |
T-2 Toxin results in decreased expression of NQO1 mRNA T-2 Toxin results in increased expression of NQO1 mRNA |
CTD |
PMID:20854872 PMID:26141394 PMID:33508416 |
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nqo2 |
N-ribosyldihydronicotinamide:quinone dehydrogenase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NQO2 protein |
CTD |
PMID:34581912 |
|
NCBI chr17:30,909,482...30,938,725
|
|
G |
Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NR0B1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr X:50,756,886...50,761,014
|
|
G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NR4A1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:132,368,399...132,389,300
|
|
G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NR5A1 mRNA |
CTD |
PMID:22982764 |
|
NCBI chr 3:22,464,786...22,486,328
|
|
G |
Nrf1 |
nuclear respiratory factor 1 |
decreases expression multiple interactions affects expression |
ISO EXP |
T-2 Toxin results in decreased expression of NRF1 protein 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of NRF1 protein] T-2 Toxin affects the expression of NRF1 mRNA NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of NRF1 protein]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter] T-2 Toxin results in decreased expression of NRF1 mRNA; T-2 Toxin results in decreased expression of NRF1 protein |
CTD |
PMID:27363784 PMID:29870751 PMID:31470059 PMID:35842139 |
|
NCBI chr 4:58,664,932...58,772,328
|
|
G |
Nrip3 |
nuclear receptor interacting protein 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of NRIP3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:173,224,532...173,249,829
|
|
G |
Nsfl1c |
NSFL1 cofactor |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to NSFL1C] |
CTD |
PMID:36863559 |
|
NCBI chr 3:160,438,708...160,463,261
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NTRK2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr17:5,560,558...5,875,899
|
|
G |
Nucb1 |
nucleobindin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of NUCB1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:105,104,793...105,135,730
|
|
G |
Nucb2 |
nucleobindin 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NUCB2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:170,750,830...170,787,356
|
|
G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of NUF2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:84,226,448...84,290,957
|
|
G |
Nup43 |
nucleoporin 43 |
increases expression |
EXP |
T-2 Toxin results in increased expression of NUP43 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:2,144,427...2,157,887
|
|
G |
Oat |
ornithine aminotransferase |
affects expression |
EXP |
T-2 Toxin affects the expression of OAT protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:196,777,973...196,797,754
|
|
G |
Ocln |
occludin |
multiple interactions decreases expression |
ISO |
illite inhibits the reaction [T-2 Toxin results in decreased expression of OCLN mRNA] T-2 Toxin results in decreased expression of OCLN mRNA; T-2 Toxin results in decreased expression of OCLN protein |
CTD |
PMID:27153755 PMID:31170431 |
|
NCBI chr 2:33,391,303...33,442,207
|
|
G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
EXP |
PINK1 promotes the reaction [T-2 Toxin results in increased expression of OPA1 mRNA] |
CTD |
PMID:36863559 |
|
NCBI chr11:84,612,943...84,690,025
|
|
G |
Ostm1 |
osteoclastogenesis associated transmembrane protein 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of OSTM1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr20:46,071,657...46,187,049
|
|
G |
P4hb |
prolyl 4-hydroxylase subunit beta |
affects expression |
EXP |
T-2 Toxin affects the expression of P4HB protein |
CTD |
PMID:26141394 |
|
NCBI chr10:105,836,972...105,848,583
|
|
G |
Pa2g4 |
proliferation-associated 2G4 |
affects expression |
EXP |
T-2 Toxin affects the expression of PA2G4 protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:1,569,326...1,576,794
|
|
G |
Pafah1b2 |
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PAFAH1B2 protein |
CTD |
PMID:34581912 |
|
NCBI chr 8:46,260,069...46,312,073
|
|
G |
Parg |
poly (ADP-ribose) glycohydrolase |
multiple interactions |
EXP |
T-2 Toxin promotes the reaction [GABPA protein binds to PARG] |
CTD |
PMID:36863559 |
|
NCBI chr16:7,436,429...7,544,276
|
|
G |
Park7 |
Parkinsonism associated deglycase |
affects expression |
EXP |
T-2 Toxin affects the expression of PARK7 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:166,636,551...166,659,825
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PARP1 mRNA; T-2 Toxin results in increased expression of PARP1 protein |
CTD |
PMID:28697680 PMID:29432840 |
|
NCBI chr13:94,839,484...94,871,295
|
|
G |
Pax6 |
paired box 6 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PAX6 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 3:92,128,772...92,157,022
|
|
G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PCK2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr15:32,997,853...33,006,691
|
|
G |
Pcna |
proliferating cell nuclear antigen |
affects expression |
EXP |
T-2 Toxin affects the expression of PCNA protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:139,951,948...139,955,820
|
|
G |
Pcsk5 |
proprotein convertase subtilisin/kexin type 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PCSK5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:214,837,847...215,267,626
|
|
G |
Pcyox1l |
prenylcysteine oxidase 1 like |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PCYOX1L mRNA |
CTD |
PMID:31863870 |
|
NCBI chr18:55,150,637...55,161,334
|
|
G |
Pdcd10 |
programmed cell death 10 |
affects expression |
EXP |
T-2 Toxin affects the expression of PDCD10 protein |
CTD |
PMID:26141394 |
|
NCBI chr 2:160,303,465...160,346,086
|
|
G |
Pdcd4 |
programmed cell death 4 |
increases expression decreases expression |
EXP ISO |
T-2 Toxin results in increased expression of PDCD4 mRNA T-2 Toxin results in decreased expression of PDCD4 mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 1:252,921,342...252,944,278
|
|
G |
Pdcd7 |
programmed cell death 7 |
increases expression |
EXP |
T-2 Toxin results in increased expression of PDCD7 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:65,862,606...65,877,333
|
|
G |
Pde10a |
phosphodiesterase 10A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PDE10A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:51,765,743...52,218,086
|
|
G |
Pde4b |
phosphodiesterase 4B |
increases expression |
ISO |
T-2 Toxin results in increased expression of PDE4B mRNA |
CTD |
PMID:36775139 |
|
NCBI chr 5:122,028,956...122,598,267
|
|
G |
Pdgfa |
platelet derived growth factor subunit A |
increases expression |
ISO |
T-2 Toxin results in increased expression of PDGFA mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:15,645,549...15,667,056
|
|
G |
Pdgfrl |
platelet-derived growth factor receptor-like |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PDGFRL mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:51,347,929...51,407,850
|
|
G |
Pdhb |
pyruvate dehydrogenase E1 subunit beta |
affects expression |
EXP |
T-2 Toxin affects the expression of PDHB protein |
CTD |
PMID:26141394 |
|
NCBI chr15:19,182,789...19,188,731
|
|
G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
affects expression |
EXP |
T-2 Toxin affects the expression of PDIA3 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:128,841,781...128,865,733
|
|
G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PDIA4 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:78,134,144...78,153,191
|
|
G |
Pdlim1 |
PDZ and LIM domain 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PDLIM1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:239,042,372...239,091,074
|
|
G |
Pdrg1 |
p53 and DNA damage regulated 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of PDRG1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:141,477,561...141,483,730
|
|
G |
Pea15 |
proliferation and apoptosis adaptor protein 15 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PEA15 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:87,190,189...87,199,811
|
|
G |
Pes1 |
pescadillo ribosomal biogenesis factor 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PES1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:78,850,754...78,867,134
|
|
G |
Pex5 |
peroxisomal biogenesis factor 5 |
multiple interactions increases expression |
EXP |
GABPA promotes the reaction [T-2 Toxin results in increased expression of PEX5 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to PEX5] |
CTD |
PMID:36863559 |
|
NCBI chr 4:157,270,671...157,296,432
|
|
G |
Pfn1 |
profilin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of PFN1 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:55,863,882...55,866,587
|
|
G |
Pgam1 |
phosphoglycerate mutase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of PGAM1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:250,673,152...250,680,762
|
|
G |
Pgk1 |
phosphoglycerate kinase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of PGK1 protein |
CTD |
PMID:26141394 |
|
NCBI chr X:75,336,988...75,352,962
|
|
G |
Pgls |
6-phosphogluconolactonase |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of PGLS protein T-2 Toxin results in increased expression of PGLS protein |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr16:18,300,317...18,305,803
|
|
G |
Pgr |
progesterone receptor |
multiple interactions |
ISO |
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA] |
CTD |
PMID:30951242 |
|
NCBI chr 8:14,354,398...14,413,271
|
|
G |
Phb1 |
prohibitin 1 |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of PHB1 protein T-2 Toxin results in increased expression of PHB1 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
|
NCBI chr10:81,102,043...81,114,815
|
|
G |
Phgdh |
phosphoglycerate dehydrogenase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PHGDH mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:185,906,962...185,936,054
|
|
G |
Phlda1 |
pleckstrin homology-like domain, family A, member 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PHLDA1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 7:48,853,690...48,855,894
|
|
G |
Pik3cb |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PIK3CB mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:108,474,017...108,579,140
|
|
G |
Pik3r2 |
phosphoinositide-3-kinase regulatory subunit 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PIK3R2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr16:18,699,389...18,708,045
|
|
G |
Pik3r3 |
phosphoinositide-3-kinase regulatory subunit 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PIK3R3 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 5:134,936,790...135,009,303
|
|
G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions increases expression |
EXP |
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of PINK1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of DNM1L mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of FIS1 mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of MFN1 mRNA]; PINK1 promotes the reaction [T-2 Toxin results in increased expression of OPA1 mRNA] T-2 Toxin results in increased expression of PINK1 mRNA; T-2 Toxin results in increased expression of PINK1 protein |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr 5:155,813,838...155,825,950
|
|
G |
Pkib |
cAMP-dependent protein kinase inhibitor beta |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PKIB mRNA |
CTD |
PMID:26141394 |
|
NCBI chr20:36,965,172...37,062,190
|
|
G |
Pkig |
cAMP-dependent protein kinase inhibitor gamma |
affects expression |
EXP |
T-2 Toxin affects the expression of PKIG protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:172,749,871...172,817,514
|
|
G |
Pkm |
pyruvate kinase M1/2 |
affects expression |
EXP |
T-2 Toxin affects the expression of PKM protein |
CTD |
PMID:26141394 |
|
NCBI chr 8:68,949,731...68,975,394
|
|
G |
Plekha1 |
pleckstrin homology domain containing A1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PLEKHA1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:185,427,982...185,479,157
|
|
G |
Plxna4 |
plexin A4 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PLXNA4 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:60,720,246...61,162,206
|
|
G |
Polr2e |
RNA polymerase II, I and III subunit E |
increases expression |
ISO |
T-2 Toxin results in increased expression of POLR2E mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 7:9,666,695...9,670,638
|
|
G |
Polr3c |
RNA polymerase III subunit C |
increases expression |
ISO |
T-2 Toxin results in increased expression of POLR3C mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 2:184,246,201...184,262,150
|
|
G |
Pop4 |
POP4 homolog, ribonuclease P/MRP subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of POP4 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:90,960,026...90,968,360
|
|
G |
Pou1f1 |
POU class 1 homeobox 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of POU1F1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr11:3,316,818...3,334,804
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression |
EXP |
T-2 Toxin results in increased expression of PPARG mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:150,095,743...150,221,104
|
|
G |
Ppargc1a |
PPARG coactivator 1 alpha |
decreases expression multiple interactions increases expression |
ISO EXP |
T-2 Toxin results in decreased expression of PPARGC1A protein 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein] T-2 Toxin results in increased expression of PPARGC1A mRNA T-2 Toxin results in decreased expression of PPARGC1A mRNA; T-2 Toxin results in decreased expression of PPARGC1A protein NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein] |
CTD |
PMID:27363784 PMID:29870751 PMID:35842139 |
|
NCBI chr14:63,073,505...63,729,215
|
|
G |
Ppargc1b |
PPARG coactivator 1 beta |
increases expression |
EXP |
T-2 Toxin results in increased expression of PPARGC1B mRNA |
CTD |
PMID:29870751 |
|
NCBI chr18:54,758,891...54,861,103
|
|
G |
Ppcs |
phosphopantothenoylcysteine synthetase |
increases expression |
ISO |
T-2 Toxin results in increased expression of PPCS mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 5:133,023,077...133,026,899
|
|
G |
Ppia |
peptidylprolyl isomerase A |
affects expression |
EXP |
T-2 Toxin affects the expression of PPIA protein |
CTD |
PMID:26141394 |
|
NCBI chr14:81,279,292...81,282,960
|
|
G |
Ppp1r10 |
protein phosphatase 1, regulatory subunit 10 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PPP1R10 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:2,827,802...2,842,418
|
|
G |
Ppp3cb |
protein phosphatase 3 catalytic subunit beta |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PPP3CB mRNA |
CTD |
PMID:34581912 |
|
NCBI chr15:3,809,182...3,854,204
|
|
G |
Pprc1 |
PPARG related coactivator 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of PPRC1 mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:244,901,985...244,918,587
|
|
G |
Prcp |
prolylcarboxypeptidase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PRCP mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:146,931,487...146,983,891
|
|
G |
Prdx3 |
peroxiredoxin 3 |
affects expression decreases expression |
EXP ISO |
T-2 Toxin affects the expression of PRDX3 protein T-2 Toxin results in decreased expression of PRDX3 mRNA; T-2 Toxin results in decreased expression of PRDX3 protein |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 1:260,001,642...260,014,064
|
|
G |
Prdx4 |
peroxiredoxin 4 |
affects expression |
EXP |
T-2 Toxin affects the expression of PRDX4 protein |
CTD |
PMID:26141394 |
|
NCBI chr X:43,876,374...43,893,815
|
|
G |
Prelp |
proline and arginine rich end leucine rich repeat protein |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PRELP mRNA |
CTD |
PMID:31863870 |
|
NCBI chr13:45,368,407...45,391,480
|
|
G |
Prickle2 |
prickle planar cell polarity protein 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PRICKLE2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:124,869,655...125,214,862
|
|
G |
Prkcb |
protein kinase C, beta |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PRKCB mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:186,263,397...186,594,743
|
|
G |
Prkcz |
protein kinase C, zeta |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of PRKCZ mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 5:171,101,774...171,212,694
|
|
G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
increases expression |
EXP |
T-2 Toxin results in increased expression of PRKN mRNA; T-2 Toxin results in increased expression of PRKN protein |
CTD |
PMID:29870751 |
|
NCBI chr 1:51,236,410...52,430,242
|
|
G |
Prmt5 |
protein arginine methyltransferase 5 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PRMT5 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr15:31,938,927...31,948,318
|
|
G |
Prpf6 |
pre-mRNA processing factor 6 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PRPF6 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:189,084,465...189,148,705
|
|
G |
Psat1 |
phosphoserine aminotransferase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PSAT1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr 1:222,623,553...222,646,187
|
|
G |
Psma4 |
proteasome 20S subunit alpha 4 |
affects expression |
EXP |
T-2 Toxin affects the expression of PSMA4 protein |
CTD |
PMID:26141394 |
|
NCBI chr 8:64,236,520...64,243,980
|
|
G |
Psma6 |
proteasome 20S subunit alpha 6 |
affects expression |
EXP |
T-2 Toxin affects the expression of PSMA6 protein |
CTD |
PMID:26141394 |
|
NCBI chr 6:78,500,676...78,531,693
|
|
G |
Psmb3 |
proteasome 20S subunit beta 3 |
affects expression |
EXP |
T-2 Toxin affects the expression of PSMB3 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:83,193,787...83,200,883
|
|
G |
Psmb7 |
proteasome 20S subunit beta 7 |
affects expression |
EXP |
T-2 Toxin affects the expression of PSMB7 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:42,767,500...42,827,470
|
|
G |
Psmc2 |
proteasome 26S subunit, ATPase 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PSMC2 mRNA; T-2 Toxin results in increased expression of PSMC2 protein |
CTD |
PMID:34581912 |
|
NCBI chr 4:14,148,080...14,162,390
|
|
G |
Psmd9 |
proteasome 26S subunit, non-ATPase 9 |
increases expression |
EXP |
T-2 Toxin results in increased expression of PSMD9 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr12:33,337,182...33,357,468
|
|
G |
Psme3 |
proteasome activator subunit 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of PSME3 protein |
CTD |
PMID:34581912 |
|
NCBI chr10:86,757,933...86,765,719
|
|
G |
Ptgis |
prostaglandin I2 synthase |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PTGIS mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:155,928,564...155,964,228
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of PTGS2 mRNA; T-2 Toxin results in increased expression of PTGS2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; Minocycline inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [T-2 Toxin results in increased expression of PTGS2 mRNA] |
CTD |
PMID:36115646 PMID:36775139 |
|
NCBI chr13:64,714,063...64,722,320
|
|
G |
Ptprc |
protein tyrosine phosphatase, receptor type, C |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of PTPRC mRNA |
CTD |
PMID:34581912 |
|
NCBI chr13:52,147,717...52,259,810
|
|
G |
Ptprf |
protein tyrosine phosphatase, receptor type, F |
increases expression |
ISO |
T-2 Toxin results in increased expression of PTPRF mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 5:131,741,959...131,824,000
|
|
G |
Pxn |
paxillin |
increases expression |
ISO |
T-2 Toxin results in increased expression of PXN mRNA |
CTD |
PMID:34581912 |
|
NCBI chr12:41,060,791...41,107,952
|
|
G |
Pyy |
peptide YY |
increases expression |
ISO |
T-2 Toxin results in increased expression of PYY protein alternative form |
CTD |
PMID:29689362 |
|
NCBI chr10:87,061,155...87,062,278
|
|
G |
Qsox1 |
quiescin sulfhydryl oxidase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of QSOX1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:67,949,780...67,987,434
|
|
G |
Qsox2 |
quiescin sulfhydryl oxidase 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of QSOX2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:29,433,091...29,462,739
|
|
G |
Rab20 |
RAB20, member RAS oncogene family |
increases expression |
ISO |
T-2 Toxin results in increased expression of RAB20 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:84,721,427...84,745,610
|
|
G |
Rab25 |
RAB25, member RAS oncogene family |
increases expression |
EXP |
T-2 Toxin results in increased expression of RAB25 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:174,000,323...174,006,422
|
|
G |
Rab27a |
RAB27A, member RAS oncogene family |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RAB27A mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:82,663,373...82,717,267
|
|
G |
Ramp1 |
receptor activity modifying protein 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of RAMP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 9:99,213,031...99,263,696
|
|
G |
Ranbp1 |
RAN binding protein 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of RANBP1 protein |
CTD |
PMID:26141394 |
|
NCBI chr11:96,246,912...96,255,145
|
|
G |
Rasal3 |
RAS protein activator like 3 |
increases expression |
EXP |
T-2 Toxin results in increased expression of RASAL3 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:11,396,554...11,411,347
|
|
G |
Rasd1 |
ras related dexamethasone induced 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RASD1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:45,265,975...45,275,279
|
|
G |
Rassf1 |
Ras association domain family member 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of RASSF1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:117,103,665...117,114,805
|
|
G |
Rassf4 |
Ras association domain family member 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RASSF4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:151,569,984...151,605,203
|
|
G |
Rb1 |
RB transcriptional corepressor 1 |
decreases phosphorylation decreases expression |
EXP |
T-2 Toxin results in decreased phosphorylation of RB1 protein T-2 Toxin results in decreased expression of RB1 mRNA |
CTD |
PMID:29567467 |
|
NCBI chr15:54,780,858...54,911,989
|
|
G |
Rbks |
ribokinase |
increases expression |
EXP |
T-2 Toxin results in increased expression of RBKS mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:30,467,724...30,544,284
|
|
G |
Rbpms2 |
RNA binding protein, mRNA processing factor 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of RBPMS2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:66,153,169...66,184,278
|
|
G |
Rcn1 |
reticulocalbin 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of RCN1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:91,841,052...91,855,295
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions affects localization increases expression |
EXP ISO |
T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter] T-2 Toxin affects the localization of RELA protein modified form T-2 Toxin results in increased expression of RELA mRNA |
CTD |
PMID:29079362 PMID:34581912 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Relb |
RELB proto-oncogene, NF-kB subunit |
increases expression |
ISO |
T-2 Toxin results in increased expression of RELB mRNA |
CTD |
PMID:36775139 |
|
NCBI chr 1:88,385,717...88,413,380
|
|
G |
Reln |
reelin |
increases expression |
ISO |
T-2 Toxin results in increased expression of RELN mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 4:12,736,177...13,162,956
|
|
G |
Rgs12 |
regulator of G-protein signaling 12 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RGS12 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr14:75,715,925...75,824,012
|
|
G |
Rgs2 |
regulator of G-protein signaling 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of RGS2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:58,350,063...58,352,666
|
|
G |
Rgs4 |
regulator of G-protein signaling 4 |
increases expression |
EXP |
T-2 Toxin results in increased expression of RGS4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr13:81,936,775...81,943,103
|
|
G |
Rheb |
Ras homolog, mTORC1 binding |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of RHEB mRNA; T-2 Toxin results in increased expression of RHEB protein MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA] |
CTD |
PMID:32240701 |
|
NCBI chr 4:11,012,173...11,053,860
|
|
G |
Rhob |
ras homolog family member B |
increases expression |
ISO |
T-2 Toxin results in increased expression of RHOB mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 6:31,363,752...31,365,926
|
|
G |
Rhoh |
ras homolog family member H |
increases expression |
EXP |
T-2 Toxin results in increased expression of RHOH mRNA |
CTD |
PMID:26141394 |
|
NCBI chr14:42,694,860...42,725,690
|
|
G |
Rlig1 |
RNA 5'-phosphate and 3'-OH ligase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RLIG1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:37,284,545...37,295,858
|
|
G |
Rp9 |
RP9, pre-mRNA splicing factor |
increases expression |
ISO |
T-2 Toxin results in increased expression of RP9 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:20,955,447...21,005,225
|
|
G |
Rpap1 |
RNA polymerase II associated protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RPAP1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:106,746,642...106,768,182
|
|
G |
Rpia |
ribose 5-phosphate isomerase A |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of RPIA mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 4:102,723,712...102,749,374
|
|
G |
Rplp2 |
ribosomal protein lateral stalk subunit P2 |
affects expression |
EXP |
T-2 Toxin affects the expression of RPLP2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:205,975,598...205,978,192
|
|
G |
Rpn2 |
ribophorin II |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of RPN2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 3:145,941,787...145,989,271
|
|
G |
Rpp21 |
ribonuclease P/MRP subunit p21 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RPP21 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr20:1,986,225...2,025,308
|
|
G |
Rpp25 |
ribonuclease P and MRP subunit p25 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RPP25 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:57,907,352...57,908,732
|
|
G |
Rpp40 |
ribonuclease P/MRP subunit p40 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RPP40 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr17:28,947,752...28,956,788
|
|
G |
Rps21-ps1 |
ribosomal protein S21, pseudogene 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of RPS21 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:153,387,133...153,387,476
|
|
G |
Rps6ka5 |
ribosomal protein S6 kinase A5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of RPS6KA5 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 6:125,558,434...125,736,576
|
|
G |
Rpsa |
ribosomal protein SA |
affects expression |
EXP |
T-2 Toxin affects the expression of RPSA protein |
CTD |
PMID:26141394 |
|
NCBI chr 8:128,728,761...128,732,736
|
|
G |
Runx2 |
RUNX family transcription factor 2 |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of RUNX2 mRNA; T-2 Toxin results in decreased expression of RUNX2 protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of RUNX2 protein] |
CTD |
PMID:35289972 PMID:36402210 |
|
NCBI chr 9:23,661,278...23,990,248
|
|
G |
Ruvbl1 |
RuvB-like AAA ATPase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of RUVBL1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr 4:122,489,754...122,524,666
|
|
G |
Ruvbl2 |
RuvB-like AAA ATPase 2 |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of RUVBL2 protein T-2 Toxin results in increased expression of RUVBL2 mRNA |
CTD |
PMID:26141394 PMID:31863870 |
|
NCBI chr 1:105,038,487...105,051,851
|
|
G |
Safb |
scaffold attachment factor B |
increases expression |
EXP |
T-2 Toxin results in increased expression of SAFB mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 9:1,417,449...1,438,408
|
|
G |
Sap30bp |
SAP30 binding protein |
increases expression |
ISO |
T-2 Toxin results in increased expression of SAP30BP mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:101,165,777...101,198,503
|
|
G |
Scpep1 |
serine carboxypeptidase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SCPEP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr10:74,200,491...74,230,107
|
|
G |
Sdha |
succinate dehydrogenase complex flavoprotein subunit A |
increases expression |
EXP |
T-2 Toxin results in increased expression of SDHA mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 1:28,935,965...28,960,936
|
|
G |
Sdhb |
succinate dehydrogenase complex iron sulfur subunit B |
increases expression |
EXP |
T-2 Toxin results in increased expression of SDHB mRNA |
CTD |
PMID:29870751 |
|
NCBI chr 5:158,547,775...158,568,589
|
|
G |
Selenos |
selenoprotein S |
increases expression |
ISO |
T-2 Toxin results in increased expression of SELS mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:119,659,779...119,669,546
|
|
G |
Sema3f |
semaphorin 3F |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SEMA3F mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:117,236,269...117,265,206
|
|
G |
Serpina3n |
serpin family A member 3N |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SERPINA3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 6:123,323,623...123,331,181
|
|
G |
Serpinb9 |
serpin family B member 9 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SERPINB9 protein |
CTD |
PMID:34581912 |
|
NCBI chr17:31,420,118...31,443,237
|
|
G |
Serpine2 |
serpin family E member 2 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SERPINE2 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 9:81,124,746...81,188,866
|
|
G |
Set |
Set nuclear proto-oncogene |
affects expression |
EXP |
T-2 Toxin affects the expression of SET protein |
CTD |
PMID:26141394 |
|
NCBI chr 3:33,732,319...33,743,433
|
|
G |
Setdb1 |
SET domain bifurcated histone lysine methyltransferase 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of SETDB1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:182,898,738...182,930,283
|
|
G |
Sf3b2 |
splicing factor 3b, subunit 2 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SF3B2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:202,570,423...202,590,774
|
|
G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SGK1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 1:24,799,391...24,916,886
|
|
G |
Sgms1 |
sphingomyelin synthase 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SGMS1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:239,409,991...239,681,195
|
|
G |
Sh3gl1 |
SH3 domain containing GRB2 like 1, endophilin A2 |
affects expression |
EXP |
T-2 Toxin affects the expression of SH3GL1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 9:842,285...869,753
|
|
G |
Skp1 |
S-phase kinase-associated protein 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of SKP1 protein |
CTD |
PMID:26141394 |
|
NCBI chr10:36,898,670...36,917,828
|
|
G |
Slc17a5 |
solute carrier family 17 member 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC17A5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:79,394,416...79,429,387
|
|
G |
Slc17a6 |
solute carrier family 17 member 6 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC17A6 mRNA |
CTD |
PMID:26314264 |
|
NCBI chr 1:101,212,489...101,252,543
|
|
G |
Slc1a5 |
solute carrier family 1 member 5 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC1A5 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:77,456,849...77,470,952
|
|
G |
Slc27a5 |
solute carrier family 27 member 5 |
increases expression |
EXP |
T-2 Toxin results in increased expression of SLC27A5 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:82,688,742...82,699,335
|
|
G |
Slc29a4 |
solute carrier family 29 member 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SLC29A4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr12:11,853,540...11,884,660
|
|
G |
Slc35g1 |
solute carrier family 35, member G1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC35G1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:236,163,593...236,172,115
|
|
G |
Slc37a3 |
solute carrier family 37, member 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC37A3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 4:68,109,314...68,153,590
|
|
G |
Slc38a1 |
solute carrier family 38, member 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC38A1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:129,612,414...129,681,727
|
|
G |
Slc7a2 |
solute carrier family 7 member 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SLC7A2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:51,417,478...51,470,784
|
|
G |
Slit1 |
slit guidance ligand 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SLIT1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:240,409,559...240,558,127
|
|
G |
Smarca1 |
SNF2 related chromatin remodeling ATPase 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SMARCA1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr X:131,858,148...131,944,639
|
|
G |
Smoc1 |
SPARC related modular calcium binding 1 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SMOC1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 6:100,701,330...100,897,441
|
|
G |
Sms |
spermine synthase |
increases expression |
ISO |
T-2 Toxin results in increased expression of SMS mRNA |
CTD |
PMID:31863870 |
|
NCBI chr X:37,516,949...37,572,657
|
|
G |
Snrpf |
small nuclear ribonucleoprotein polypeptide F |
affects expression |
EXP |
T-2 Toxin affects the expression of SNRPF protein |
CTD |
PMID:26141394 |
|
NCBI chr 7:28,130,427...28,137,129
|
|
G |
Snu13 |
small nuclear ribonucleoprotein 13 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SNU13 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 7:115,445,415...115,451,008
|
|
G |
Socs1 |
suppressor of cytokine signaling 1 |
increases expression multiple interactions |
ISO |
T-2 Toxin results in increased expression of SOCS1 mRNA MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA] |
CTD |
PMID:32240701 |
|
NCBI chr10:5,389,574...5,391,265
|
|
G |
Sod1 |
superoxide dismutase 1 |
increases expression affects expression decreases activity decreases expression |
ISO EXP |
T-2 Toxin results in increased expression of SOD1 mRNA T-2 Toxin affects the expression of SOD1 protein T-2 Toxin results in decreased activity of SOD1 protein T-2 Toxin results in decreased expression of SOD1 mRNA |
CTD |
PMID:26138683 PMID:26141394 PMID:27842451 PMID:33508416 |
|
NCBI chr11:42,942,742...42,948,399
|
|
G |
Sod2 |
superoxide dismutase 2 |
decreases expression increases expression |
EXP ISO |
T-2 Toxin results in decreased expression of SOD2 mRNA T-2 Toxin results in increased expression of SOD2 mRNA |
CTD |
PMID:26141394 PMID:29870751 PMID:30091165 |
|
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Sp1 |
Sp1 transcription factor |
multiple interactions |
ISO |
T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter] |
CTD |
PMID:31470059 |
|
NCBI chr 7:135,419,864...135,450,513
|
|
G |
Sp7 |
Sp7 transcription factor |
decreases expression multiple interactions |
ISO |
T-2 Toxin results in decreased expression of SP7 protein 3-methyladenine promotes the reaction [T-2 Toxin results in decreased expression of SP7 protein] |
CTD |
PMID:35289972 PMID:36402210 |
|
NCBI chr 7:135,363,193...135,373,376
|
|
G |
Spc25 |
SPC25 component of NDC80 kinetochore complex |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SPC25 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:53,930,013...53,988,940
|
|
G |
Spcs3 |
signal peptidase complex subunit 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SPCS3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr16:37,305,358...37,310,792
|
|
G |
Sphk1 |
sphingosine kinase 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SPHK1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:102,257,413...102,263,086
|
|
G |
Spi1 |
Spi-1 proto-oncogene |
increases expression |
ISO |
T-2 Toxin results in increased expression of SPI1 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:77,059,744...77,093,730
|
|
G |
Sqstm1 |
sequestosome 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SQSTM1 mRNA T-2 Toxin results in increased expression of SQSTM1 protein |
CTD |
PMID:34581912 PMID:35289972 |
|
NCBI chr10:35,026,598...35,037,750
|
|
G |
Srfbp1 |
serum response factor binding protein 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of SRFBP1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr18:45,920,389...45,945,385
|
|
G |
Ssr3 |
signal sequence receptor subunit 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of SSR3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:149,605,005...149,625,069
|
|
G |
Sstr1 |
somatostatin receptor 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SSTR1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 6:75,832,292...75,836,806
|
|
G |
Star |
steroidogenic acute regulatory protein |
decreases expression multiple interactions |
EXP ISO |
T-2 Toxin results in decreased expression of STAR mRNA; T-2 Toxin results in decreased expression of STAR protein [T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA] |
CTD |
PMID:25542145 PMID:25962641 PMID:30951242 |
|
NCBI chr16:72,969,824...72,974,447
|
|
G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions increases expression increases phosphorylation decreases expression |
ISO EXP |
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein] T-2 Toxin results in decreased expression of STAT1 mRNA |
CTD |
PMID:22454431 PMID:26141394 |
|
NCBI chr 9:56,911,522...56,951,926
|
|
G |
Stat2 |
signal transducer and activator of transcription 2 |
increases expression decreases expression |
ISO EXP |
T-2 Toxin results in increased expression of STAT2 mRNA T-2 Toxin results in decreased expression of STAT2 mRNA |
CTD |
PMID:22454431 PMID:26141394 |
|
NCBI chr 7:702,565...718,349
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases phosphorylation increases expression decreases expression |
ISO EXP |
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein] T-2 Toxin results in decreased expression of STAT3 mRNA |
CTD |
PMID:22454431 PMID:26141394 |
|
NCBI chr10:86,311,528...86,363,513
|
|
G |
Stat5b |
signal transducer and activator of transcription 5B |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of STAT5B mRNA |
CTD |
PMID:34581912 |
|
NCBI chr10:85,704,841...85,775,856
|
|
G |
Stk4 |
serine/threonine kinase 4 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of STK4 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 3:173,165,238...173,247,135
|
|
G |
Stoml2 |
stomatin like 2 |
affects expression |
EXP |
T-2 Toxin affects the expression of STOML2 protein |
CTD |
PMID:26141394 |
|
NCBI chr 5:57,256,227...57,259,824
|
|
G |
Sucnr1 |
succinate receptor 1 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SUCNR1 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:144,219,066...144,230,568
|
|
G |
Suox |
sulfite oxidase |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SUOX mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 7:1,687,666...1,691,759
|
|
G |
Sybu |
syntabulin |
increases expression decreases expression |
EXP ISO |
T-2 Toxin results in increased expression of SYBU mRNA T-2 Toxin results in decreased expression of SYBU mRNA |
CTD |
PMID:26141394 PMID:31863870 |
|
NCBI chr 7:75,847,000...75,948,919
|
|
G |
Syt11 |
synaptotagmin 11 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SYT11 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:176,503,845...176,530,354
|
|
G |
Syt17 |
synaptotagmin 17 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of SYT17 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 1:172,695,275...172,761,906
|
|
G |
Tac1 |
tachykinin, precursor 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of TAC1 protein |
CTD |
PMID:30336258 |
|
NCBI chr 4:36,645,344...36,653,548
|
|
G |
Taldo1 |
transaldolase 1 |
affects expression |
EXP |
T-2 Toxin affects the expression of TALDO1 protein |
CTD |
PMID:26141394 |
|
NCBI chr 1:205,923,196...205,933,526
|
|
G |
Tatdn1 |
TatD DNase domain containing 1 |
increases expression |
ISO |
T-2 Toxin results in increased expression of TATDN1 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:90,449,979...90,481,000
|
|
G |
Tbxa2r |
thromboxane A2 receptor |
increases expression decreases expression |
EXP ISO |
T-2 Toxin results in increased expression of TBXA2R mRNA T-2 Toxin results in decreased expression of TBXA2R mRNA |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 7:9,034,077...9,041,489
|
|
G |
Tcp1 |
t-complex 1 |
affects expression increases expression |
EXP ISO |
T-2 Toxin affects the expression of TCP1 protein T-2 Toxin results in increased expression of TCP1 protein |
CTD |
PMID:26141394 PMID:34581912 |
|
NCBI chr 1:50,376,848...50,384,527
|
|
G |
Terc |
telomerase RNA component |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of TERC mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 2:112,815,654...112,816,041
|
|
G |
Tf |
transferrin |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of TF mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 8:103,789,780...103,816,487
|
|
G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions decreases expression increases expression |
ISO EXP |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of TFAM protein] T-2 Toxin results in increased expression of TFAM mRNA NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [T-2 Toxin results in decreased expression of TFAM protein] T-2 Toxin results in decreased expression of TFAM mRNA; T-2 Toxin results in decreased expression of TFAM protein GABPA promotes the reaction [T-2 Toxin results in increased expression of TFAM mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFAM] |
CTD |
PMID:27363784 PMID:29870751 PMID:35842139 PMID:36863559 |
|
NCBI chr20:17,356,243...17,368,293
|
|
G |
Tfb1m |
transcription factor B1, mitochondrial |
affects expression multiple interactions increases expression |
EXP |
T-2 Toxin affects the expression of TFB1M mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB1M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB1M] |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr 1:44,115,240...44,161,737
|
|
G |
Tfb2m |
transcription factor B2, mitochondrial |
affects expression multiple interactions increases expression |
EXP |
T-2 Toxin affects the expression of TFB2M mRNA GABPA promotes the reaction [T-2 Toxin results in increased expression of TFB2M mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to TFB2M] |
CTD |
PMID:29870751 PMID:36863559 |
|
NCBI chr13:91,278,889...91,296,709
|
|
G |
Tfe3 |
transcription factor binding to IGHM enhancer 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of TFE3 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr X:14,729,547...14,742,830
|
|
G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
increases expression |
EXP |
T-2 Toxin results in increased expression of TGFBR1 protein |
CTD |
PMID:35213812 |
|
NCBI chr 5:66,449,348...66,506,371
|
|
G |
Tgfbr2 |
transforming growth factor, beta receptor 2 |
increases expression |
EXP |
T-2 Toxin results in increased expression of TGFBR2 protein |
CTD |
PMID:35213812 |
|
NCBI chr 8:124,672,677...124,761,741
|
|
G |
Tgfbr3 |
transforming growth factor beta receptor 3 |
increases expression |
ISO |
T-2 Toxin results in increased expression of TGFBR3 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr14:2,634,294...2,810,269
|
|
G |
Tgm2 |
transglutaminase 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of TGM2 mRNA |
CTD |
PMID:34581912 |
|
NCBI chr 3:167,192,612...167,221,845
|
|
G |
Thbs1 |
thrombospondin 1 |
decreases expression increases expression |
ISO |
T-2 Toxin results in decreased expression of THBS1 mRNA T-2 Toxin results in increased expression of THBS1 mRNA |
CTD |
PMID:31863870 PMID:34581912 |
|
NCBI chr 3:125,510,250...125,525,402
|
|
G |
Thbs2 |
thrombospondin 2 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of THBS2 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:64,343,523...64,372,918
|
|
G |
Thbs3 |
thrombospondin 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of THBS3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:176,919,549...176,931,357
|
|
G |
Thrb |
thyroid hormone receptor beta |
multiple interactions |
ISO |
T-2 Toxin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] |
CTD |
PMID:31077750 |
|
NCBI chr15:10,115,954...10,465,231
|
|
G |
Timm50 |
translocase of inner mitochondrial membrane 50 |
increases expression |
ISO |
T-2 Toxin results in increased expression of TIMM50 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 1:92,702,437...92,710,311
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
decreases expression multiple interactions affects expression |
ISO |
T-2 Toxin results in decreased expression of TIMP1 protein Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein] T-2 Toxin affects the expression of TIMP1 mRNA |
CTD |
PMID:21112371 PMID:21144892 |
|
NCBI chr X:3,766,509...3,772,578
|
|
G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
decreases expression multiple interactions affects expression |
ISO |
T-2 Toxin results in decreased expression of TIMP2 protein Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP2 protein] T-2 Toxin affects the expression of TIMP2 mRNA |
CTD |
PMID:21112371 PMID:21144892 |
|
NCBI chr10:104,041,604...104,089,214
|
|
G |
Timp3 |
TIMP metallopeptidase inhibitor 3 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of TIMP3 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 7:19,408,539...19,459,558
|
|
G |
Tkt |
transketolase |
affects expression |
EXP |
T-2 Toxin affects the expression of TKT protein |
CTD |
PMID:26141394 |
|
NCBI chr16:5,723,764...5,748,702
|
|
G |
Tmem102 |
transmembrane protein 102 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of TMEM102 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr10:54,523,901...54,525,997
|
|
G |
Tmem123 |
transmembrane protein 123 |
decreases expression |
EXP |
T-2 Toxin results in decreased expression of TMEM123 mRNA |
CTD |
PMID:26141394 |
|
NCBI chr 8:4,922,077...4,952,228
|
|
G |
Tmem167a |
transmembrane protein 167A |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of TMEM167A mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 2:21,197,799...21,216,746
|
|
G |
Tmem25 |
transmembrane protein 25 |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of TMEM25 mRNA |
CTD |
PMID:31863870 |
|
NCBI chr 8:54,003,907...54,009,469
|
|
G |
Tmem50b |
transmembrane protein 50B |
decreases expression |
ISO |
T-2 Toxin results in decreased expression of TMEM50B mRNA |
CTD |
PMID:31863870 |
|
NCBI chr11:30,804,835...30,837,675
|
|
G< |