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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:HT-2 toxin
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Accession:CHEBI:138861 term browser browse the term
Definition:A trichothecene mycotoxin that is T-2 toxin in which the acetyloxy group at position 4S has been hydrolysed to the corresponding hydroxy group. It is the major metabolite of T-2 toxin.
Synonyms:exact_synonym: 15-(acetyloxy)-3alpha,4beta-dihydroxy-12,13-epoxytrichothec-9-en-8alpha-yl 3-methylbutanoate
 related_synonym: Formula=C22H32O8;   HT-2;   InChI=1S/C22H32O8/c1-11(2)6-16(24)29-14-8-21(9-27-13(4)23)15(7-12(14)3)30-19-17(25)18(26)20(21,5)22(19)10-28-22/h7,11,14-15,17-19,25-26H,6,8-10H2,1-5H3/t14-,15+,17+,18+,19+,20+,21+,22-/m0/s1;   InChIKey=PNKLMTPXERFKEN-MLXHEQMXSA-N;   SMILES=[H][C@@]12O[C@]3([H])C=C(C)[C@H](C[C@]3(COC(C)=O)[C@@](C)([C@H](O)[C@H]1O)[C@]21CO1)OC(=O)CC(C)C;   mycotoxin HT-2
 xref: CAS:26934-87-2;   KEGG:C19952;   KNApSAcK:C00012651
 xref_mesh: MESH:C012351
 xref: MetaCyc:CPD-18504;   PMID:11352533;   PMID:27929394;   PMID:28093223;   PMID:28425967;   PMID:28780481;   PMID:28937260;   PMID:29710820;   PMID:29909314;   PMID:30831213;   PMID:30870695;   PMID:30903560;   PMID:31072003;   PMID:31232057;   PMID:31409003;   PMID:31731600;   PMID:32062580;   PMID:32217092;   PMID:32275576;   PMID:32298583;   PMID:32466723;   PMID:32604961;   PMID:32871192;   PMID:32910237;   PMID:32990831;   PMID:6696412



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HT-2 toxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO HT-2 toxin results in increased activity of CASP3 protein CTD PMID:19428930 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO HT-2 toxin results in decreased expression of CYP11A mRNA CTD PMID:22982764 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression ISO HT-2 toxin results in decreased expression of CYP17A1 mRNA CTD PMID:22982764 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO HT-2 toxin results in decreased expression of CYP19A1 mRNA CTD PMID:22982764 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO HT-2 toxin results in increased expression of CYP1A1 mRNA CTD PMID:22982764 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO HT-2 toxin results in increased expression of EPHX1 mRNA CTD PMID:22982764 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Gip gastric inhibitory polypeptide multiple interactions ISO HT-2 toxin results in increased expression of and results in increased secretion of GIP protein CTD PMID:28666375 NCBI chr10:80,968,410...80,976,506
Ensembl chr10:80,968,352...80,976,503
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO HT-2 toxin results in decreased expression of HMGCR mRNA CTD PMID:22982764 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 increases expression ISO HT-2 toxin results in increased expression of HSD17B1 mRNA CTD PMID:22982764 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
JBrowse link
T-2 toxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions
decreases expression
ISO Selenium inhibits the reaction [T-2 Toxin results in decreased expression of A2M mRNA]; Selenium promotes the reaction [T-2 Toxin results in decreased expression of A2M protein]
T-2 Toxin results in decreased expression of A2M mRNA; T-2 Toxin results in decreased expression of A2M protein
CTD PMID:21144892 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Aars1 alanyl-tRNA synthetase 1 decreases expression EXP T-2 Toxin results in decreased expression of AARS mRNA CTD PMID:26141394 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression EXP T-2 Toxin results in decreased expression of ABCB1A mRNA CTD PMID:26141394 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abraxas2 abraxas 2, BRISC complex subunit increases expression ISO T-2 Toxin results in increased expression of ABRAXAS2 mRNA CTD PMID:31863870 NCBI chr 1:187,647,078...187,672,660
Ensembl chr 1:187,647,067...187,672,655
JBrowse link
G Acan aggrecan decreases expression ISO T-2 Toxin results in decreased expression of ACAN mRNA; T-2 Toxin results in decreased expression of ACAN protein CTD PMID:16624732 PMID:18196609 PMID:22800716 PMID:31863870 NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 affects expression EXP T-2 Toxin affects the expression of ACAT2 protein CTD PMID:26141394 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acly ATP citrate lyase decreases expression EXP T-2 Toxin results in decreased expression of ACLY mRNA CTD PMID:26141394 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Aco2 aconitase 2 affects expression EXP T-2 Toxin affects the expression of ACO2 protein CTD PMID:26141394 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Actb actin, beta affects expression EXP T-2 Toxin affects the expression of ACTB protein CTD PMID:26141394 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 increases expression ISO T-2 Toxin results in increased expression of ADAMTS4 mRNA CTD PMID:22800716 NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 increases expression ISO T-2 Toxin results in increased expression of ADAMTS5 mRNA CTD PMID:18196609 PMID:22800716 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
JBrowse link
G Adprh ADP-ribosylarginine hydrolase affects expression EXP T-2 Toxin affects the expression of ADPRH protein CTD PMID:26141394 NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931
JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO T-2 Toxin results in decreased expression of AHR protein CTD PMID:31470059 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ak2 adenylate kinase 2 increases expression ISO T-2 Toxin results in increased expression of AK2 mRNA CTD PMID:31863870 NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632
JBrowse link
G Akirin2 akirin 2 increases expression EXP T-2 Toxin results in increased expression of AKIRIN2 mRNA CTD PMID:26141394 NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568
JBrowse link
G Akna AT-hook transcription factor decreases expression
affects localization
multiple interactions
EXP T-2 Toxin results in decreased expression of AKNA mRNA
T-2 Toxin affects the localization of AKNA protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA]; T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter]; T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter]
CTD PMID:26141394 PMID:29079362 NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP T-2 Toxin results in decreased expression of AKT1 mRNA CTD PMID:26141394 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt1s1 AKT1 substrate 1 increases expression EXP T-2 Toxin results in increased expression of AKT1S1 mRNA CTD PMID:26141394 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression
increases expression
EXP T-2 Toxin affects the expression of ALDH1A1 protein
T-2 Toxin results in increased expression of ALDH1A1 mRNA
CTD PMID:26141394 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression EXP T-2 Toxin results in decreased expression of ALDOC mRNA CTD PMID:26141394 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Angptl7 angiopoietin like 7 decreases expression ISO T-2 Toxin results in decreased expression of ANGPTL7 mRNA CTD PMID:31863870 NCBI chr 5:158,932,094...158,937,597
Ensembl chr 5:158,932,794...158,937,324
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B affects expression EXP T-2 Toxin affects the expression of ANP32B protein CTD PMID:26141394 NCBI chr 5:60,743,077...60,765,726
Ensembl chr 5:60,743,443...60,765,717
JBrowse link
G Anxa5 annexin A5 affects expression EXP T-2 Toxin affects the expression of ANXA5 protein CTD PMID:26141394 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apoe apolipoprotein E increases expression EXP T-2 Toxin results in increased expression of APOE mRNA CTD PMID:26141394 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G App amyloid beta precursor protein decreases expression EXP T-2 Toxin results in decreased expression of APP mRNA CTD PMID:26141394 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aprt adenine phosphoribosyl transferase affects expression EXP T-2 Toxin affects the expression of APRT protein CTD PMID:26141394 NCBI chr19:50,626,436...50,628,404
Ensembl chr19:50,626,202...50,628,431
JBrowse link
G Areg amphiregulin multiple interactions ISO T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA] CTD PMID:30951242 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression EXP T-2 Toxin results in decreased expression of ARHGAP18 mRNA CTD PMID:26141394 NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256
JBrowse link
G Arl5c ADP-ribosylation factor like GTPase 5C increases expression EXP T-2 Toxin results in increased expression of ARL5C mRNA CTD PMID:26141394 NCBI chr10:82,985,213...82,993,425
Ensembl chr10:82,985,216...82,992,002
JBrowse link
G Arsa arylsulfatase A decreases expression EXP T-2 Toxin results in decreased expression of ARSA mRNA CTD PMID:26141394 NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783
JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 decreases expression ISO T-2 Toxin results in decreased expression of ASAP3 mRNA CTD PMID:31863870 NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073
JBrowse link
G Asb14 ankyrin repeat and SOCS box-containing 14 increases expression EXP T-2 Toxin results in increased expression of ASB14 mRNA CTD PMID:26141394 NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135
JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 increases expression EXP T-2 Toxin results in increased expression of ASB5 mRNA CTD PMID:26141394 NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109
JBrowse link
G Asb6 ankyrin repeat and SOCS box-containing 6 increases expression EXP T-2 Toxin results in increased expression of ASB6 mRNA CTD PMID:26141394 NCBI chr 3:14,110,628...14,115,276
Ensembl chr 3:14,110,628...14,115,242
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO T-2 Toxin results in decreased expression of ASNS mRNA CTD PMID:31863870 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression ISO T-2 Toxin results in decreased expression of ASS1 mRNA CTD PMID:31863870 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atg12 autophagy related 12 increases expression ISO T-2 Toxin results in increased expression of ATG12 protein CTD PMID:26138683 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg14 autophagy related 14 increases expression ISO T-2 Toxin results in increased expression of ATG14 mRNA CTD PMID:26138683 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
JBrowse link
G Atg3 autophagy related 3 increases expression
multiple interactions
EXP
ISO
T-2 Toxin results in increased expression of ATG3 protein
T-2 Toxin results in increased expression of ATG3 mRNA; T-2 Toxin results in increased expression of ATG3 protein
ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein]
CTD PMID:29870751 PMID:32240701 NCBI chr11:55,624,928...55,653,212
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Atg5 autophagy related 5 affects expression EXP T-2 Toxin affects the expression of ATG5 protein CTD PMID:29413859 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atm ATM serine/threonine kinase increases phosphorylation ISO T-2 Toxin results in increased phosphorylation of ATM protein CTD PMID:20150440 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp11a ATPase phospholipid transporting 11A decreases expression EXP T-2 Toxin results in decreased expression of ATP11A mRNA CTD PMID:26141394 NCBI chr16:76,657,752...76,767,640
Ensembl chr16:76,657,752...76,767,640
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP T-2 Toxin results in decreased expression of ATP1A1 mRNA CTD PMID:26141394 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha affects expression EXP T-2 Toxin affects the expression of ATP5F1A protein CTD PMID:26141394 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta affects expression EXP T-2 Toxin affects the expression of ATP5F1B protein CTD PMID:26141394 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d affects expression EXP T-2 Toxin affects the expression of ATP5H protein CTD PMID:26141394 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP T-2 Toxin affects the expression of ATP6V1A protein CTD PMID:26141394 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 affects expression EXP T-2 Toxin affects the expression of ATP6V1B2 protein CTD PMID:26141394 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745
JBrowse link
G Atp8b2 ATPase phospholipid transporting 8B2 decreases expression ISO T-2 Toxin results in decreased expression of ATP8B2 mRNA CTD PMID:31863870 NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:175,378,517...175,401,883
JBrowse link
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor increases expression ISO T-2 Toxin results in increased expression of AUP1 mRNA CTD PMID:31863870 NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346
JBrowse link
G B2m beta-2 microglobulin increases expression ISO T-2 Toxin results in increased expression of B2M protein CTD PMID:33508416 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bag5 BAG cochaperone 5 increases expression EXP T-2 Toxin results in increased expression of BAG5 mRNA CTD PMID:26141394 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
affects expression
increases expression
multiple interactions
ISO
EXP
T-2 Toxin affects the localization of BAX protein
T-2 Toxin affects the expression of BAX protein
T-2 Toxin results in increased expression of BAX mRNA; T-2 Toxin results in increased expression of BAX protein
Selenium inhibits the reaction [T-2 Toxin results in increased expression of BAX mRNA]
CTD PMID:16307838 PMID:19524637 PMID:19541794 PMID:21296132 PMID:26138683 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression EXP T-2 Toxin results in increased expression of BBC3 mRNA CTD PMID:26141394 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein increases expression ISO T-2 Toxin results in increased expression of BCCIP mRNA CTD PMID:31863870 NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:188,512,367...188,524,958
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
EXP
ISO
T-2 Toxin results in increased expression of BCL2 mRNA; T-2 Toxin results in increased expression of BCL2 protein
T-2 Toxin results in decreased expression of BCL2 mRNA; T-2 Toxin results in decreased expression of BCL2 protein
CTD PMID:19524637 PMID:21296132 PMID:29870751 PMID:33508416 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
affects expression
ISO
EXP
T-2 Toxin results in decreased expression of BCL2L1 mRNA; T-2 Toxin results in decreased expression of BCL2L1 protein
T-2 Toxin affects the expression of BCL2L1 protein
CTD PMID:29413859 PMID:29432840 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
EXP T-2 Toxin results in increased expression of BECN1 mRNA
3-methyladenine inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Selenium deficiency inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Sirolimus promotes the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]
CTD PMID:30629952 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO T-2 Toxin results in decreased expression of BID protein CTD PMID:29432840 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP T-2 Toxin results in increased expression of BNIP3L mRNA CTD PMID:29870751 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 affects expression EXP T-2 Toxin affects the expression of BPNT1 protein CTD PMID:26141394 NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503
JBrowse link
G Bud23 BUD23, rRNA methyltransferase and ribosome maturation factor increases expression ISO T-2 Toxin results in increased expression of BUD23 mRNA CTD PMID:31863870 NCBI chr12:21,629,551...21,640,758
Ensembl chr12:21,629,536...21,640,751
JBrowse link
G Calm1 calmodulin 1 affects expression EXP T-2 Toxin affects the expression of CALM1 protein CTD PMID:26141394 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Capns1 calpain, small subunit 1 affects expression EXP T-2 Toxin affects the expression of CAPNS1 protein CTD PMID:26141394 NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795
JBrowse link
G Cars cysteinyl-tRNA synthetase decreases expression EXP T-2 Toxin results in decreased expression of CARS mRNA CTD PMID:26141394 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941
JBrowse link
G Casp3 caspase 3 multiple interactions
affects expression
increases activity
increases expression
EXP
ISO
3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; Selenium deficiency promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; Sirolimus inhibits the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP3 protein
T-2 Toxin affects the expression of CASP3 protein
Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein]; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein]
T-2 Toxin results in increased expression of CASP3 mRNA; T-2 Toxin results in increased expression of CASP3 protein; T-2 Toxin results in increased expression of CASP3 protein modified form
CTD PMID:19428930 PMID:19524637 PMID:19541794 PMID:21295106 PMID:21296132 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity ISO T-2 Toxin results in increased activity of CASP7 protein CTD PMID:19524637 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions
increases activity
EXP
ISO
T-2 Toxin results in increased expression of CASP8 mRNA
Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein]
CTD PMID:26141394 PMID:29432840 PMID:29567467 PMID:29870751 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
increases expression
ISO
EXP
T-2 Toxin results in increased activity of CASP9 protein
Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; brusatol promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein]; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein]
T-2 Toxin results in increased expression of CASP9 mRNA
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; T-2 Toxin results in increased cleavage of and results in increased activity of CASP9 protein
CTD PMID:19524637 PMID:21296132 PMID:29432840 PMID:29567467 PMID:33508416 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases activity
increases expression
decreases activity
multiple interactions
decreases expression
ISO
EXP
T-2 Toxin results in increased activity of CAT protein
T-2 Toxin results in increased expression of CAT mRNA
T-2 Toxin results in decreased activity of CAT protein
T-2 Toxin affects the expression of and affects the activity of CAT protein
T-2 Toxin results in decreased expression of CAT mRNA
CTD PMID:19526462 PMID:21112371 PMID:23929680 PMID:29432840 PMID:29870751 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression EXP T-2 Toxin affects the expression of CBR1 protein CTD PMID:26141394 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Ccdc137 coiled-coil domain containing 137 increases expression ISO T-2 Toxin results in increased expression of CCDC137 mRNA CTD PMID:31863870 NCBI chr10:105,730,776...105,737,158
Ensembl chr10:105,730,739...105,737,158
JBrowse link
G Ccdc34 coiled-coil domain containing 34 increases expression ISO T-2 Toxin results in increased expression of CCDC34 mRNA CTD PMID:31863870 NCBI chr 3:96,552,992...96,588,303
Ensembl chr 3:96,552,992...96,588,146
JBrowse link
G Ccn3 cellular communication network factor 3 decreases expression ISO T-2 Toxin results in decreased expression of CCN3 mRNA CTD PMID:31863870 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Ccnb1ip1 cyclin B1 interacting protein 1 increases expression EXP T-2 Toxin results in increased expression of CCNB1IP1 mRNA CTD PMID:26141394 NCBI chr15:24,014,905...24,031,357
Ensembl chr15:24,014,908...24,028,475
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO
EXP
T-2 Toxin results in decreased expression of CCND1 mRNA
T-2 Toxin results in decreased expression of CCND1 mRNA; T-2 Toxin results in decreased expression of CCND1 protein
CTD PMID:22454431 PMID:29567467 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cd24 CD24 molecule decreases expression ISO T-2 Toxin results in decreased expression of CD24 mRNA CTD PMID:31863870 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions
decreases expression
ISO Selenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein]
T-2 Toxin results in decreased expression of CD44 mRNA; T-2 Toxin results in decreased expression of CD44 protein
CTD PMID:18196609 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) decreases expression ISO T-2 Toxin results in decreased expression of CD55 mRNA CTD PMID:31863870 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cdca5 cell division cycle associated 5 increases expression EXP T-2 Toxin results in increased expression of CDCA5 mRNA CTD PMID:26141394 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Cdca7 cell division cycle associated 7 increases expression EXP T-2 Toxin results in increased expression of CDCA7 mRNA CTD PMID:26141394 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
JBrowse link
G Cdca8 cell division cycle associated 8 increases expression EXP T-2 Toxin results in increased expression of CDCA8 mRNA CTD PMID:26141394 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression EXP T-2 Toxin results in decreased expression of CDK4 mRNA; T-2 Toxin results in decreased expression of CDK4 protein CTD PMID:29567467 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 increases expression EXP T-2 Toxin results in increased expression of CDK5RAP1 mRNA CTD PMID:26141394 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO
EXP
T-2 Toxin results in increased expression of CDKN1A mRNA
T-2 Toxin results in increased expression of CDKN1A mRNA; T-2 Toxin results in increased expression of CDKN1A protein
CTD PMID:22454431 PMID:29567467 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression EXP T-2 Toxin results in increased expression of CDKN2A mRNA; T-2 Toxin results in increased expression of CDKN2A protein CTD PMID:29567467 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO T-2 Toxin results in increased expression of CDKN3 mRNA CTD PMID:31863870 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cfl1 cofilin 1 affects expression EXP T-2 Toxin affects the expression of CFL1 protein CTD PMID:26141394 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions ISO [T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA
T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]
CTD PMID:25962641 PMID:30951242 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 increases expression EXP T-2 Toxin results in increased expression of CGRRF1 mRNA CTD PMID:26141394 NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases activity
ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of CHEK2 protein] CTD PMID:20150440 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chpf chondroitin polymerizing factor decreases expression ISO T-2 Toxin results in decreased expression of CHPF mRNA CTD PMID:31863870 NCBI chr 9:76,963,178...76,967,878
Ensembl chr 9:76,963,184...76,967,878
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit decreases expression ISO T-2 Toxin results in decreased expression of CHRNA4 mRNA CTD PMID:26314264 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression ISO T-2 Toxin results in decreased expression of CHRNB2 mRNA CTD PMID:26314264 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Ckb creatine kinase B affects expression EXP T-2 Toxin affects the expression of CKB protein CTD PMID:26141394 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression EXP T-2 Toxin results in decreased expression of CKMT2 mRNA CTD PMID:26141394 NCBI chr 2:23,079,920...23,110,518
Ensembl chr 2:23,079,918...23,110,430
JBrowse link
G Cldn3 claudin 3 multiple interactions
decreases expression
ISO illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN3 mRNA] CTD PMID:27153755 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Cldn4 claudin 4 multiple interactions
decreases expression
ISO illite inhibits the reaction [T-2 Toxin results in decreased expression of CLDN4 mRNA] CTD PMID:27153755 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Clic1 chloride intracellular channel 1 affects expression EXP T-2 Toxin affects the expression of CLIC1 protein CTD PMID:26141394 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Clu clusterin decreases expression ISO T-2 Toxin results in decreased expression of CLU mRNA CTD PMID:31863870 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnpy2 canopy FGF signaling regulator 2 affects expression EXP T-2 Toxin affects the expression of CNPY2 protein CTD PMID:26141394 NCBI chr 7:748,877...754,352
Ensembl chr 7:749,008...755,519
JBrowse link
G Cntf ciliary neurotrophic factor increases expression EXP T-2 Toxin results in increased expression of CNTF mRNA CTD PMID:26141394 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
JBrowse link
G Col10a1 collagen type X alpha 1 chain decreases expression ISO T-2 Toxin results in decreased expression of COL10A1 mRNA CTD PMID:22800716 NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
JBrowse link
G Col11a1 collagen type XI alpha 1 chain decreases expression ISO T-2 Toxin results in decreased expression of COL11A1 mRNA CTD PMID:31863870 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases expression ISO T-2 Toxin results in decreased expression of COL15A1 mRNA CTD PMID:31863870 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO T-2 Toxin results in decreased expression of COL1A1 mRNA CTD PMID:22800716 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO T-2 Toxin results in decreased expression of COL2A1 mRNA CTD PMID:22800716 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Col9a1 collagen type IX alpha 1 chain decreases expression ISO T-2 Toxin results in decreased expression of COL9A1 mRNA CTD PMID:22800716 NCBI chr 9:26,585,034...26,668,222
Ensembl chr 9:26,585,034...26,668,213
JBrowse link
G Cope COPI coat complex subunit epsilon affects expression EXP T-2 Toxin affects the expression of COPE protein CTD PMID:26141394 NCBI chr16:19,114,871...19,125,527
Ensembl chr16:19,114,871...19,128,907
JBrowse link
G Copz1 COPI coat complex subunit zeta 1 increases expression ISO T-2 Toxin results in increased expression of COPZ1 mRNA CTD PMID:31863870 NCBI chr 7:134,409,523...134,435,661
Ensembl chr 7:134,409,799...134,435,662
JBrowse link
G Coq5 coenzyme Q5, methyltransferase increases expression ISO T-2 Toxin results in increased expression of COQ5 mRNA CTD PMID:31863870 NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848
JBrowse link
G Coro1c coronin 1C increases expression ISO T-2 Toxin results in increased expression of CORO1C mRNA CTD PMID:31863870 NCBI chr12:42,712,960...42,785,179
Ensembl chr12:42,712,991...42,785,179
JBrowse link
G Coro2b coronin 2B decreases expression ISO T-2 Toxin results in decreased expression of CORO2B mRNA CTD PMID:31863870 NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302
JBrowse link
G Cox19 cytochrome c oxidase assembly factor COX19 increases expression ISO T-2 Toxin results in increased expression of COX19 mRNA CTD PMID:31863870 NCBI chr12:15,303,535...15,313,014
Ensembl chr12:15,303,551...15,313,014
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions
decreases expression
ISO 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of COX4I1 protein] CTD PMID:27363784 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C affects expression EXP T-2 Toxin affects the expression of COX6C protein CTD PMID:26141394 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
JBrowse link
G Cox6c-ps1 cytochrome c oxidase subunit VIc, pseudogene decreases expression EXP T-2 Toxin results in decreased expression of COX6C-PS1 mRNA CTD PMID:26141394 NCBI chr19:52,192,612...52,193,470
Ensembl chr19:52,192,612...52,193,470
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects localization
multiple interactions
EXP T-2 Toxin affects the localization of CREB1 protein modified form
T-2 Toxin promotes the reaction [CREB1 protein binds to AKNA promoter]
CTD PMID:29079362 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 decreases expression EXP T-2 Toxin results in decreased expression of CREB3L1 mRNA CTD PMID:26141394 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
JBrowse link
G Creb5 cAMP responsive element binding protein 5 increases expression ISO T-2 Toxin results in increased expression of CREB5 mRNA CTD PMID:31863870 NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325
JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP T-2 Toxin results in decreased expression of CREM mRNA CTD PMID:26141394 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 decreases expression EXP T-2 Toxin results in decreased expression of CRTC3 mRNA CTD PMID:26141394 NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500
JBrowse link
G Csf1 colony stimulating factor 1 increases expression EXP T-2 Toxin results in increased expression of CSF1 mRNA CTD PMID:26141394 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Cst3 cystatin C increases expression ISO T-2 Toxin results in increased expression of CST3 protein CTD PMID:33508416 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Ctrb1 chymotrypsinogen B1 affects expression EXP T-2 Toxin affects the expression of CTRB1 protein CTD PMID:26141394 NCBI chr19:39,652,931...39,657,666
Ensembl chr19:39,652,933...39,657,688
JBrowse link
G Ctsa cathepsin A decreases expression ISO T-2 Toxin results in decreased expression of CTSA mRNA CTD PMID:31863870 NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
JBrowse link
G Cwc27 CWC27 spliceosome associated cyclophilin increases expression ISO T-2 Toxin results in increased expression of CWC27 mRNA CTD PMID:31863870 NCBI chr 2:35,764,674...35,975,908
Ensembl chr 2:35,764,686...35,975,872
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 decreases expression EXP T-2 Toxin results in decreased expression of CYB5R1 mRNA CTD PMID:26141394 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458
JBrowse link
G Cyc1 cytochrome c-1 increases expression EXP T-2 Toxin results in increased expression of CYC1 mRNA CTD PMID:29870751 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO T-2 Toxin affects the localization of CYCS protein CTD PMID:19541794 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 decreases expression EXP T-2 Toxin results in decreased expression of CYFIP1 mRNA CTD PMID:26141394 NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO
EXP
[T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP11A1 protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of CYP11A1 mRNA
T-2 Toxin results in decreased expression of CYP11A1 mRNA
CTD PMID:25962641 PMID:26141394 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO [T-2 Toxin co-treated with CGA protein] results in decreased activity of CYP17A1 protein CTD PMID:25962641 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO T-2 Toxin results in decreased expression of CYP19A1 mRNA
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]
CTD PMID:22982764 PMID:30951242 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Dactinomycin inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; Resveratrol inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter]; T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter]
T-2 Toxin results in increased expression of CYP1A1 mRNA; T-2 Toxin results in increased expression of CYP1A1 protein
CTD PMID:21453744 PMID:22982764 PMID:31470059 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cytl1 cytokine like 1 decreases expression ISO T-2 Toxin results in decreased expression of CYTL1 mRNA CTD PMID:31863870 NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886
JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) decreases expression EXP T-2 Toxin results in decreased expression of DARS2 mRNA CTD PMID:26141394 NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934
JBrowse link
G Dcps decapping enzyme, scavenger increases expression ISO T-2 Toxin results in increased expression of DCPS mRNA CTD PMID:31863870 NCBI chr 8:33,468,669...33,524,407 JBrowse link
G Dcx doublecortin increases expression ISO T-2 Toxin results in increased expression of DCX mRNA CTD PMID:26314264 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase increases expression ISO T-2 Toxin results in increased expression of DCXR mRNA CTD PMID:31863870 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO T-2 Toxin results in increased expression of DDB2 mRNA CTD PMID:31863870 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
EXP T-2 Toxin results in increased expression of DDIT3 mRNA; T-2 Toxin results in increased expression of DDIT3 protein
Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of DDIT3 protein]
CTD PMID:26141394 PMID:29454614 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx52 DExD-box helicase 52 increases expression ISO T-2 Toxin results in increased expression of DDX52 mRNA CTD PMID:31863870 NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO T-2 Toxin results in decreased expression of DHCR24 mRNA CTD PMID:31863870 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 decreases expression ISO T-2 Toxin results in decreased expression of DNAJC10 mRNA CTD PMID:31863870 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 affects expression EXP T-2 Toxin affects the expression of DNAJC4 protein CTD PMID:26141394 NCBI chr 1:204,178,189...204,182,412
Ensembl chr 1:204,178,191...204,182,387
JBrowse link
G Dnase1l1 deoxyribonuclease 1-like 1 decreases expression ISO T-2 Toxin results in decreased expression of DNASE1L1 mRNA CTD PMID:31863870 NCBI chr  X:152,056,942...152,065,518
Ensembl chr  X:152,056,942...152,065,518
JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal decreases expression ISO T-2 Toxin results in decreased expression of DNASE2 mRNA CTD PMID:31863870 NCBI chr19:23,244,661...23,247,329
Ensembl chr19:23,244,664...23,247,376
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression EXP T-2 Toxin results in increased expression of DNMT1 mRNA; T-2 Toxin results in increased expression of DNMT1 protein CTD PMID:31279042 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha increases expression EXP T-2 Toxin results in increased expression of DNMT3A mRNA; T-2 Toxin results in increased expression of DNMT3A protein CTD PMID:31279042 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dok3 docking protein 3 increases expression EXP T-2 Toxin results in increased expression of DOK3 mRNA CTD PMID:26141394 NCBI chr17:9,109,633...9,115,188
Ensembl chr17:9,109,597...9,115,188
JBrowse link
G Dph1 diphthamide biosynthesis 1 increases expression EXP T-2 Toxin results in increased expression of DPH1 mRNA CTD PMID:26141394 NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850
JBrowse link
G Dpy19l1 dpy-19 like C-mannosyltransferase 1 decreases expression ISO T-2 Toxin results in decreased expression of DPY19L1 mRNA CTD PMID:31863870 NCBI chr 8:22,933,163...23,021,461
Ensembl chr 8:22,933,163...23,021,751
JBrowse link
G Dstn destrin, actin depolymerizing factor affects expression EXP T-2 Toxin affects the expression of DSTN protein CTD PMID:26141394 NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP T-2 Toxin results in decreased expression of DUSP1 mRNA CTD PMID:26141394 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Ecm2 extracellular matrix protein 2 decreases expression ISO T-2 Toxin results in decreased expression of ECM2 mRNA CTD PMID:31863870 NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516
JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta affects expression EXP T-2 Toxin affects the expression of EEF1D protein CTD PMID:26141394 NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP T-2 Toxin affects the expression of EEF1G protein CTD PMID:26141394 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 affects expression EXP T-2 Toxin affects the expression of EEF2 protein CTD PMID:26141394 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Efhd1 EF-hand domain family, member D1 decreases expression ISO T-2 Toxin results in decreased expression of EFHD1 mRNA CTD PMID:31863870 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 increases expression EXP T-2 Toxin results in increased expression of EIF2AK2 mRNA CTD PMID:26141394 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 decreases expression ISO T-2 Toxin results in decreased expression of EIF2AK3 mRNA CTD PMID:31863870 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
EXP T-2 Toxin results in increased phosphorylation of EIF2S1 protein
Selenomethionine inhibits the reaction [T-2 Toxin results in increased phosphorylation of EIF2S1 protein]
CTD PMID:29454614 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif3d eukaryotic translation initiation factor 3, subunit D increases expression EXP T-2 Toxin results in increased expression of EIF3D mRNA CTD PMID:26141394 NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206
JBrowse link
G Eif3g eukaryotic translation initiation factor 3, subunit G increases expression EXP T-2 Toxin results in increased expression of EIF3G mRNA CTD PMID:26141394 NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808
JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I affects expression EXP T-2 Toxin affects the expression of EIF3I protein CTD PMID:26141394 NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
JBrowse link
G Eif3j eukaryotic translation initiation factor 3, subunit J increases expression EXP T-2 Toxin results in increased expression of EIF3J mRNA CTD PMID:26141394 NCBI chr 3:108,985,103...109,007,341
Ensembl chr 3:108,985,118...109,007,953
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 increases expression EXP T-2 Toxin results in increased expression of EIF4A2 mRNA CTD PMID:26141394 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A affects expression EXP T-2 Toxin affects the expression of EIF5A protein CTD PMID:26141394 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 affects expression EXP T-2 Toxin affects the expression of EIF6 protein CTD PMID:26141394 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401
JBrowse link
G Eloc elongin C affects expression EXP T-2 Toxin affects the expression of ELOC protein CTD PMID:26141394 NCBI chr 5:2,661,527...2,677,893
Ensembl chr 5:2,661,724...2,677,890
JBrowse link
G Eno1 enolase 1 affects expression EXP T-2 Toxin affects the expression of ENO1 protein CTD PMID:26141394 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Eomes eomesodermin increases expression ISO T-2 Toxin results in increased expression of EOMES mRNA CTD PMID:26314264 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions
increases expression
ISO BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 mRNA]; BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 protein]
T-2 Toxin results in increased expression of EPAS1 mRNA; T-2 Toxin results in increased expression of EPAS1 protein
CTD PMID:22800716 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epyc epiphycan decreases expression ISO T-2 Toxin results in decreased expression of EPYC mRNA CTD PMID:31863870 NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135
JBrowse link
G Ereg epiregulin multiple interactions ISO T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA] CTD PMID:30951242 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Ergic2 ERGIC and golgi 2 decreases expression EXP T-2 Toxin results in decreased expression of ERGIC2 mRNA CTD PMID:26141394 NCBI chr 4:181,092,025...181,123,060
Ensembl chr 4:181,090,808...181,123,060
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 decreases expression EXP T-2 Toxin results in decreased expression of ERMP1 mRNA CTD PMID:26141394 NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions
ISO T-2 Toxin results in increased expression of ERN1 protein
ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein]
CTD PMID:31170431 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 decreases expression
multiple interactions
ISO T-2 Toxin results in decreased expression of ERN2 protein
ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of ERN2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein]
CTD PMID:31170431 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha decreases expression EXP T-2 Toxin results in decreased expression of ERO1A mRNA CTD PMID:26141394 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP T-2 Toxin affects the expression of ERP29 protein CTD PMID:26141394 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Esrra estrogen related receptor, alpha affects expression EXP T-2 Toxin affects the expression of ESRRA mRNA CTD PMID:29870751 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Ezr ezrin affects expression EXP T-2 Toxin affects the expression of EZR protein CTD PMID:26141394 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fam102a family with sequence similarity 102, member A decreases expression ISO T-2 Toxin results in decreased expression of FAM102A mRNA CTD PMID:31863870 NCBI chr 3:15,823,147...15,854,651
Ensembl chr 3:15,823,144...15,854,643
JBrowse link
G Fam162a family with sequence similarity 162, member A increases expression ISO T-2 Toxin results in increased expression of FAM162A mRNA CTD PMID:31863870 NCBI chr11:64,680,937...64,711,239
Ensembl chr11:64,680,323...64,711,239
JBrowse link
G Fam216a family with sequence similarity 216, member A increases expression ISO T-2 Toxin results in increased expression of FAM216A mRNA CTD PMID:31863870 NCBI chr12:34,198,526...34,207,673
Ensembl chr12:34,198,526...34,207,665
JBrowse link
G Fanci FA complementation group I increases expression EXP T-2 Toxin results in increased expression of FANCI mRNA CTD PMID:26141394 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
JBrowse link
G Fbxo2 F-box protein 2 affects expression EXP T-2 Toxin affects the expression of FBXO2 protein CTD PMID:26141394 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355
JBrowse link
G Fbxo22 F-box protein 22 increases expression ISO T-2 Toxin results in increased expression of FBXO22 mRNA CTD PMID:31863870 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148
JBrowse link
G Fbxw4 F-box and WD repeat domain containing 4 increases expression EXP T-2 Toxin results in increased expression of FBXW4 mRNA CTD PMID:26141394 NCBI chr 1:244,426,892...244,514,188
Ensembl chr 1:244,426,896...244,514,163
JBrowse link
G Fcgr2b Fc gamma receptor IIb increases expression EXP T-2 Toxin results in increased expression of FCGR2B mRNA CTD PMID:26141394 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fgf4 fibroblast growth factor 4 decreases expression EXP T-2 Toxin results in decreased expression of FGF4 mRNA CTD PMID:26141394 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 affects expression EXP T-2 Toxin affects the expression of FKBP4 protein CTD PMID:26141394 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833
JBrowse link
G Fmod fibromodulin decreases expression ISO T-2 Toxin results in decreased expression of FMOD mRNA CTD PMID:31863870 NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133
JBrowse link
G Fscn1 fascin actin-bundling protein 1 affects expression EXP T-2 Toxin affects the expression of FSCN1 protein CTD PMID:26141394 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
multiple interactions
EXP
ISO
T-2 Toxin results in decreased expression of FSHB protein
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of AREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of EREG mRNA]; T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Estradiol]; T-2 Toxin inhibits the reaction [FSHB protein results in increased secretion of Progesterone]
CTD PMID:26569305 PMID:30951242 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fubp1 far upstream element binding protein 1 affects expression EXP T-2 Toxin affects the expression of FUBP1 protein CTD PMID:26141394 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Fuca1 alpha-L-fucosidase 1 decreases expression ISO T-2 Toxin results in decreased expression of FUCA1 mRNA CTD PMID:31863870 NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase affects expression
decreases expression
EXP T-2 Toxin affects the expression of G6PD protein
T-2 Toxin results in decreased expression of G6PD mRNA
CTD PMID:26141394 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 increases expression EXP T-2 Toxin results in increased expression of GABBR1 mRNA CTD PMID:26141394 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha increases expression EXP T-2 Toxin results in increased expression of GABPA mRNA CTD PMID:29870751 NCBI chr11:23,888,586...23,917,612
Ensembl chr11:23,888,815...23,917,605
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP T-2 Toxin results in increased expression of GADD45G mRNA CTD PMID:26141394 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gadd45gip1 GADD45G interacting protein 1 increases expression ISO T-2 Toxin results in increased expression of GADD45GIP1 mRNA CTD PMID:31863870 NCBI chr19:23,320,662...23,323,211
Ensembl chr19:23,320,159...23,323,236
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression ISO T-2 Toxin results in increased expression of GAL mRNA CTD PMID:31863870 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 decreases expression ISO T-2 Toxin results in decreased expression of GALNT1 mRNA CTD PMID:31863870 NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression
decreases expression
EXP T-2 Toxin affects the expression of GAPDH protein
T-2 Toxin results in decreased expression of GAPDH mRNA
CTD PMID:26141394 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gas6 growth arrest specific 6 decreases expression ISO T-2 Toxin results in decreased expression of GAS6 mRNA CTD PMID:31863870 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gask1b golgi associated kinase 1B increases expression ISO T-2 Toxin results in increased expression of GASK1B mRNA CTD PMID:31863870 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
JBrowse link
G Gatb glutamyl-tRNA amidotransferase subunit B increases expression ISO T-2 Toxin results in increased expression of GATB mRNA CTD PMID:31863870 NCBI chr 2:170,930,536...171,017,062
Ensembl chr 2:170,930,542...171,016,695
JBrowse link
G Gatm glycine amidinotransferase decreases expression EXP T-2 Toxin results in decreased expression of GATM mRNA CTD PMID:26141394 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression
increases expression
ISO T-2 Toxin results in decreased expression of GCLC mRNA
T-2 Toxin results in increased expression of GCLC mRNA
CTD PMID:20854872 PMID:33508416 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression
increases expression
ISO T-2 Toxin results in decreased expression of GCLM mRNA
T-2 Toxin results in increased expression of GCLM mRNA
CTD PMID:20854872 PMID:33508416 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf5 growth differentiation factor 5 increases expression ISO T-2 Toxin results in increased expression of GDF5 mRNA CTD PMID:31863870 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 decreases expression ISO T-2 Toxin results in decreased expression of GDPD5 mRNA CTD PMID:31863870 NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 decreases expression ISO T-2 Toxin results in decreased expression of GFPT1 mRNA CTD PMID:31863870 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
JBrowse link
G Gh1 growth hormone 1 multiple interactions
decreases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; AKNA protein affects the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; farnesylthiosalicylic acid inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA]; T-2 Toxin results in decreased expression of and results in decreased secretion of GH1 protein CTD PMID:26141394 PMID:29079362 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression EXP T-2 Toxin results in decreased expression of GHITM mRNA CTD PMID:26141394 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
JBrowse link
G Ghrh growth hormone releasing hormone increases expression EXP T-2 Toxin results in increased expression of GHRH mRNA CTD PMID:26141394 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889
JBrowse link
G Gip gastric inhibitory polypeptide multiple interactions
increases expression
ISO T-2 Toxin results in increased expression of and results in increased secretion of GIP protein
T-2 Toxin results in increased expression of GIP protein
CTD PMID:28666375 PMID:29689362 NCBI chr10:80,968,410...80,976,506
Ensembl chr10:80,968,352...80,976,503
JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression ISO T-2 Toxin results in decreased expression of GLMP mRNA CTD PMID:31863870 NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases expression EXP T-2 Toxin results in decreased expression of GNRH1 mRNA CTD PMID:26569305 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Gpatch4 G patch domain containing 4 increases expression ISO T-2 Toxin results in increased expression of GPATCH4 mRNA CTD PMID:31863870 NCBI chr 2:173,499,700...173,520,346
Ensembl chr 2:173,509,897...173,518,684
JBrowse link
G Gpc4 glypican 4 decreases expression ISO T-2 Toxin results in decreased expression of GPC4 mRNA CTD PMID:31863870 NCBI chr  X:131,644,711...131,755,349
Ensembl chr  X:131,644,704...131,755,284
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity ISO T-2 Toxin results in increased activity of GPT protein CTD PMID:23929680 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
decreases expression
EXP
ISO
T-2 Toxin results in increased expression of GPX1 mRNA
T-2 Toxin results in decreased expression of GPX1 mRNA
CTD PMID:26141394 PMID:29870751 PMID:30091165 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression EXP T-2 Toxin results in decreased expression of GPX2 mRNA CTD PMID:26141394 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Grb10 growth factor receptor bound protein 10 increases expression EXP T-2 Toxin results in increased expression of GRB10 mRNA CTD PMID:26141394 NCBI chr14:86,495,054...86,602,815
Ensembl chr14:86,495,054...86,602,806
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression ISO T-2 Toxin results in decreased expression of GRIA2 mRNA CTD PMID:26314264 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A increases expression ISO T-2 Toxin results in increased expression of GRIN2A mRNA CTD PMID:26314264 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grm4 glutamate metabotropic receptor 4 decreases expression EXP T-2 Toxin results in decreased expression of GRM4 mRNA CTD PMID:26141394 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Grn granulin precursor decreases expression ISO T-2 Toxin results in decreased expression of GRN mRNA CTD PMID:31863870 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsdma gasdermin A decreases expression EXP T-2 Toxin results in decreased expression of GSDMA mRNA CTD PMID:26141394 NCBI chr10:83,614,336...83,639,543
Ensembl chr10:83,627,051...83,639,543
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression EXP T-2 Toxin results in decreased expression of GSK3B mRNA CTD PMID:26141394 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
multiple interactions
affects expression
ISO T-2 Toxin results in decreased expression of GSR mRNA
T-2 Toxin affects the expression of and affects the activity of GSR protein
T-2 Toxin affects the expression of GSR mRNA
CTD PMID:19526462 PMID:23929680 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase affects expression EXP T-2 Toxin affects the expression of GSS protein CTD PMID:26141394 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsto2 glutathione S-transferase omega 2 increases expression EXP T-2 Toxin results in increased expression of GSTO2 mRNA CTD PMID:26141394 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects expression EXP T-2 Toxin affects the expression of GSTP1 protein CTD PMID:26141394 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 increases expression EXP T-2 Toxin results in increased expression of GSTT2 mRNA CTD PMID:26141394 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
JBrowse link
G H1f10 H1.10 linker histone increases expression EXP T-2 Toxin results in increased expression of H1F10 mRNA CTD PMID:26141394 NCBI chr 4:120,440,515...120,444,705
Ensembl chr 4:120,440,870...120,441,448
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases activity
ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of H2AX protein] CTD PMID:20150440 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) decreases expression EXP T-2 Toxin results in decreased expression of H6PD mRNA CTD PMID:26141394 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 decreases expression ISO T-2 Toxin results in decreased expression of HAPLN1 mRNA CTD PMID:31863870 NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
JBrowse link
G Has2 hyaluronan synthase 2 decreases expression
increases expression
ISO T-2 Toxin results in decreased expression of HAS2 mRNA
T-2 Toxin results in increased expression of HAS2 mRNA
CTD PMID:18196609 PMID:31863870 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
JBrowse link
G Hbs1l HBS1-like translational GTPase increases expression ISO T-2 Toxin results in increased expression of HBS1L mRNA CTD PMID:31863870 NCBI chr 1:16,092,529...16,170,082
Ensembl chr 1:16,092,547...16,170,074
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase increases expression EXP T-2 Toxin results in increased expression of HCK mRNA CTD PMID:26141394 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Helq helicase, POLQ-like increases expression EXP T-2 Toxin results in increased expression of HELQ mRNA CTD PMID:26141394 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960
JBrowse link
G Hexim2 HEXIM P-TEFb complex subunit 2 increases expression EXP T-2 Toxin results in increased expression of HEXIM2 mRNA CTD PMID:26141394 NCBI chr10:88,077,870...88,084,776
Ensembl chr10:88,079,014...88,084,775
JBrowse link
G Hipk3 homeodomain interacting protein kinase 3 decreases expression EXP T-2 Toxin results in decreased expression of HIPK3 mRNA CTD PMID:26141394 NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO T-2 Toxin results in increased expression of H2BC5 mRNA CTD PMID:31863870 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO T-2 Toxin results in increased expression of HMGA1 mRNA CTD PMID:31863870 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO T-2 Toxin results in decreased expression of HMGCR mRNA CTD PMID:22982764 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
increases expression
ISO T-2 Toxin results in decreased expression of HMOX1 mRNA; T-2 Toxin results in decreased expression of HMOX1 protein
T-2 Toxin results in increased expression of HMOX1 mRNA
CTD PMID:20854872 PMID:29432840 PMID:33508416 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 affects expression EXP T-2 Toxin affects the expression of HNRNPA2B1 protein CTD PMID:26141394 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 affects expression EXP T-2 Toxin affects the expression of HNRNPA3 protein CTD PMID:26141394 NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B affects expression EXP T-2 Toxin affects the expression of HNRNPAB protein CTD PMID:26141394 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 affects expression EXP T-2 Toxin affects the expression of HNRNPH1 protein CTD PMID:26141394 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K affects expression EXP T-2 Toxin affects the expression of HNRNPK protein CTD PMID:26141394 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
JBrowse link
G Hp haptoglobin increases expression EXP T-2 Toxin results in increased expression of HP mRNA CTD PMID:26141394 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 affects expression EXP T-2 Toxin affects the expression of HSP90AA1 protein CTD PMID:26141394 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects expression
decreases expression
EXP T-2 Toxin affects the expression of HSP90AB1 protein
T-2 Toxin results in decreased expression of HSP90AB1 mRNA
CTD PMID:26141394 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 affects expression EXP T-2 Toxin affects the expression of HSP90B1 protein CTD PMID:26141394 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 affects expression EXP T-2 Toxin affects the expression of HSPA4 protein CTD PMID:26141394 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
affects expression
ISO
EXP
T-2 Toxin results in increased degradation of and results in decreased expression of HSPA5 protein
T-2 Toxin results in increased expression of HSPA5 protein
T-2 Toxin results in increased expression of HSPA5 mRNA; T-2 Toxin results in increased expression of HSPA5 protein
Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 mRNA]; Selenomethionine inhibits the reaction [T-2 Toxin results in increased expression of HSPA5 protein]
T-2 Toxin affects the expression of HSPA5 protein
CTD PMID:19336499 PMID:26141394 PMID:29454614 PMID:31170431 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects expression EXP T-2 Toxin affects the expression of HSPA8 protein CTD PMID:26141394 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects expression EXP T-2 Toxin affects the expression of HSPA9 protein CTD PMID:26141394 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression EXP T-2 Toxin affects the expression of HSPD1 protein CTD PMID:26141394 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htra4 HtrA serine peptidase 4 decreases expression EXP T-2 Toxin results in decreased expression of HTRA4 mRNA CTD PMID:26141394 NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074
JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression EXP T-2 Toxin results in increased expression of HUS1 mRNA CTD PMID:26141394 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Hyi hydroxypyruvate isomerase increases expression ISO T-2 Toxin results in increased expression of HYI mRNA CTD PMID:31863870 NCBI chr 5:131,894,575...131,897,709
Ensembl chr 5:131,894,598...131,897,251
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 decreases expression EXP T-2 Toxin results in decreased expression of IDH1 mRNA CTD PMID:26141394 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha affects expression EXP T-2 Toxin affects the expression of IDH3A protein CTD PMID:26141394 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Idh3b isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta increases expression ISO T-2 Toxin results in increased expression of IDH3B mRNA CTD PMID:31863870 NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
JBrowse link
G Ifitm10 interferon induced transmembrane protein 10 decreases expression ISO T-2 Toxin results in decreased expression of IFITM10 mRNA CTD PMID:31863870 NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:197,507,503...197,525,151
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression EXP T-2 Toxin results in increased expression of IFRD1 mRNA CTD PMID:26141394 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 increases expression EXP T-2 Toxin results in increased expression of IGF2BP2 mRNA CTD PMID:26141394 NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression EXP T-2 Toxin results in decreased expression of IGFBP4 mRNA CTD PMID:26141394 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Igfbpl1 insulin-like growth factor binding protein-like 1 increases expression EXP T-2 Toxin results in increased expression of IGFBPL1 mRNA CTD PMID:26141394 NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833
JBrowse link
G Igflr1 IGF-like family receptor 1 increases expression EXP T-2 Toxin results in increased expression of IGFLR1 mRNA CTD PMID:26141394 NCBI chr 1:85,818,428...85,821,032
Ensembl chr 1:85,816,326...85,821,030
JBrowse link
G Il10 interleukin 10 affects expression
decreases expression
ISO T-2 Toxin affects the expression of IL10 mRNA
T-2 Toxin results in decreased expression of IL10 mRNA; T-2 Toxin results in decreased expression of IL10 protein
CTD PMID:22960706 PMID:31170431 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il11 interleukin 11 increases expression
decreases methylation
multiple interactions
EXP T-2 Toxin results in increased expression of IL11 mRNA; T-2 Toxin results in increased expression of IL11 protein
T-2 Toxin results in decreased methylation of IL11 promoter
Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of IL11 promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL11 mRNA]
CTD PMID:29079362 PMID:31279042 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
JBrowse link
G Il1a interleukin 1 alpha increases expression
decreases methylation
ISO
EXP
T-2 Toxin results in increased expression of IL1A mRNA
T-2 Toxin results in decreased methylation of IL1A promoter
CTD PMID:21112371 PMID:31279042 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; SB 203580 inhibits the reaction [T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]]; Selenium promotes the reaction [T-2 Toxin results in increased expression of IL1B protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CXCL8 protein]; T-2 Toxin promotes the reaction [IL1B protein results in increased expression of CYP1A1 mRNA]; T-2 Toxin promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]
T-2 Toxin results in increased expression of IL1B mRNA; T-2 Toxin results in increased expression of IL1B protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]
CTD PMID:18196609 PMID:21112371 PMID:21453744 PMID:22454431 PMID:22960706 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 affects secretion
increases expression
ISO T-2 Toxin affects the secretion of IL2 protein
T-2 Toxin results in increased expression of IL2 mRNA
CTD PMID:8560498 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il22 interleukin 22 increases expression EXP T-2 Toxin results in increased expression of IL22 mRNA CTD PMID:26141394 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186
JBrowse link
G Il4 interleukin 4 affects secretion
decreases expression
ISO T-2 Toxin affects the secretion of IL4 protein
T-2 Toxin results in decreased expression of IL4 mRNA
CTD PMID:8560498 PMID:22960706 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 affects secretion ISO T-2 Toxin affects the secretion of IL5 protein CTD PMID:8560498 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases methylation
affects expression
increases expression
ISO
EXP
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; ATG3 protein inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]
T-2 Toxin results in decreased methylation of IL6 promoter
T-2 Toxin affects the expression of IL6 mRNA
T-2 Toxin results in increased expression of IL6 mRNA; T-2 Toxin results in increased expression of IL6 protein
AKNA protein affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of IL6 protein]
CTD PMID:21112371 PMID:22454431 PMID:22960706 PMID:29079362 PMID:31170431 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Islr immunoglobulin superfamily containing leucine-rich repeat decreases expression ISO T-2 Toxin results in decreased expression of ISLR mRNA CTD PMID:31863870 NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130
JBrowse link
G Itga10 integrin subunit alpha 10 decreases expression ISO T-2 Toxin results in decreased expression of ITGA10 mRNA CTD PMID:31863870 NCBI chr 2:184,182,869...184,202,172
Ensembl chr 2:184,182,869...184,202,172
JBrowse link
G Itga11 integrin subunit alpha 11 decreases expression ISO T-2 Toxin results in decreased expression of ITGA11 mRNA CTD PMID:31863870 NCBI chr 8:63,145,950...63,254,717
Ensembl chr 8:63,146,001...63,254,407
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO T-2 Toxin results in decreased expression of ITGB5 mRNA CTD PMID:31863870 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itgbl1 integrin subunit beta like 1 decreases expression ISO T-2 Toxin results in decreased expression of ITGBL1 mRNA CTD PMID:31863870 NCBI chr15:100,780,184...101,041,734
Ensembl chr15:100,780,184...101,041,733
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO T-2 Toxin results in increased expression of JAK1 mRNA CTD PMID:22454431 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jak2 Janus kinase 2 multiple interactions
increases expression
ISO alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA] CTD PMID:22454431 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jam3 junctional adhesion molecule 3 decreases expression ISO T-2 Toxin results in decreased expression of JAM3 mRNA CTD PMID:31863870 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355
JBrowse link
G Jdp2 Jun dimerization protein 2 decreases expression ISO T-2 Toxin results in decreased expression of JDP2 mRNA CTD PMID:31863870 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP T-2 Toxin results in increased expression of JUN mRNA CTD PMID:26141394 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 increases expression ISO T-2 Toxin results in increased expression of KCNMA1 mRNA CTD PMID:31863870 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 decreases expression ISO T-2 Toxin results in decreased expression of KDELR2 mRNA CTD PMID:31863870 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 decreases expression ISO T-2 Toxin results in decreased expression of KDELR3 mRNA CTD PMID:31863870 NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600
JBrowse link
G Kif16b kinesin family member 16B decreases expression EXP T-2 Toxin results in decreased expression of KIF16B mRNA CTD PMID:26141394 NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019
JBrowse link
G Kitlg KIT ligand decreases expression ISO T-2 Toxin results in decreased expression of KITLG mRNA; T-2 Toxin results in decreased expression of KITLG protein CTD PMID:26314264 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Krt1 keratin 1 decreases expression EXP T-2 Toxin results in decreased expression of KRT1 mRNA CTD PMID:26141394 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Krt8 keratin 8 affects expression EXP T-2 Toxin affects the expression of KRT8 protein CTD PMID:26141394 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lama5 laminin subunit alpha 5 increases expression EXP T-2 Toxin results in increased expression of LAMA5 mRNA CTD PMID:26141394 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451
JBrowse link
G Lars1 leucyl-tRNA synthetase 1 decreases expression EXP T-2 Toxin results in decreased expression of LARS mRNA CTD PMID:26141394 NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
JBrowse link
G Lgals1 galectin 1 affects expression EXP T-2 Toxin affects the expression of LGALS1 protein CTD PMID:26141394 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 decreases expression ISO T-2 Toxin results in decreased expression of LGR5 mRNA CTD PMID:31863870 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression EXP T-2 Toxin results in decreased expression of LHB protein CTD PMID:26569305 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO 1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of LHCGR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA] CTD PMID:30951242 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G LOC680039 hypothetical protein LOC680039 decreases expression ISO T-2 Toxin results in decreased expression of KIAA0232 mRNA CTD PMID:31863870 NCBI chr14:74,094,421...74,159,316
Ensembl chr14:74,094,488...74,159,326
JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 affects expression
decreases expression
EXP
ISO
T-2 Toxin affects the expression of LRPAP1 protein
T-2 Toxin results in decreased expression of LRPAP1 mRNA
CTD PMID:26141394 PMID:31863870 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 decreases expression ISO T-2 Toxin results in decreased expression of LTBP2 mRNA CTD PMID:31863870 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
EXP T-2 Toxin results in increased expression of MAP1LC3B mRNA
T-2 Toxin results in increased expression of and results in increased cleavage of MAP1LC3B protein
CTD PMID:29413859 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mars2 methionyl-tRNA synthetase 2, mitochondrial decreases expression EXP T-2 Toxin results in decreased expression of MARS2 mRNA CTD PMID:26141394 NCBI chr 9:56,720,408...56,729,991
Ensembl chr 9:56,720,983...56,723,820
JBrowse link
G Mbtps1 membrane-bound transcription factor peptidase, site 1 decreases expression ISO T-2 Toxin results in decreased expression of MBTPS1 mRNA CTD PMID:31863870 NCBI chr19:47,561,598...47,612,769
Ensembl chr19:47,561,598...47,612,791
JBrowse link
G Mcf2l MCF.2 cell line derived transforming sequence-like decreases expression EXP T-2 Toxin results in decreased expression of MCF2L mRNA CTD PMID:26141394 NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 affects expression EXP T-2 Toxin affects the expression of MCM7 protein CTD PMID:26141394 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Mdh1 malate dehydrogenase 1 affects expression EXP T-2 Toxin affects the expression of MDH1 protein CTD PMID:26141394 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP
ISO
T-2 Toxin results in increased expression of MDM2 mRNA CTD PMID:26141394 PMID:31863870 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Megf6 multiple EGF-like-domains 6 decreases expression ISO T-2 Toxin results in decreased expression of MEGF6 mRNA CTD PMID:31863870 NCBI chr 5:164,738,272...164,839,142
Ensembl chr 5:164,738,352...164,839,139
JBrowse link
G Meltf melanotransferrin decreases expression ISO T-2 Toxin results in decreased expression of MELTF mRNA CTD PMID:31863870 NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300
JBrowse link
G Mesd mesoderm development LRP chaperone affects expression EXP T-2 Toxin affects the expression of MESD protein CTD PMID:26141394 NCBI chr 1:137,866,707...137,879,999
Ensembl chr 1:137,874,242...137,879,999
JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator decreases expression ISO T-2 Toxin results in decreased expression of METRNL mRNA CTD PMID:31863870 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
JBrowse link
G Mettl9 methyltransferase like 9 decreases expression ISO T-2 Toxin results in decreased expression of METTL9 mRNA CTD PMID:31863870 NCBI chr 1:175,575,805...175,623,065
Ensembl chr 1:175,577,890...175,623,061
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing decreases expression ISO T-2 Toxin results in decreased expression of MFGE8 mRNA CTD PMID:31863870 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
JBrowse link
G Mir155 microRNA 155 multiple interactions
increases expression
ISO MIR155 mRNA affects the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of ATG3 protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]
T-2 Toxin results in increased expression of MIR155 mRNA
CTD PMID:32240701 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 decreases expression ISO T-2 Toxin results in decreased expression of MKNK2 mRNA CTD PMID:31863870 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mmd monocyte to macrophage differentiation-associated decreases expression EXP T-2 Toxin results in decreased expression of MMD mRNA CTD PMID:26141394 NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO T-2 Toxin results in increased expression of MMP1 protein CTD PMID:21144892 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO T-2 Toxin results in increased expression of MMP12 mRNA CTD PMID:22800716 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
increases expression
ISO Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein]
T-2 Toxin results in increased expression of MMP13 mRNA; T-2 Toxin results in increased expression of MMP13 protein
CTD PMID:21144892 PMID:22800716 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp2 matrix metallopeptidase 2 increases activity
decreases expression
ISO T-2 Toxin results in increased activity of MMP2 protein
T-2 Toxin results in decreased expression of MMP2 mRNA
CTD PMID:21112371 PMID:22960706 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO T-2 Toxin results in increased expression of MMP3 mRNA CTD PMID:22800716 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects expression
increases expression
multiple interactions
increases activity
ISO
EXP
T-2 Toxin affects the expression of MMP9 mRNA
T-2 Toxin results in increased expression of MMP9 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]; SB 203580 inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA]
T-2 Toxin results in increased expression of and results in increased activity of MMP9 protein
T-2 Toxin results in increased activity of MMP9 protein
CTD PMID:21112371 PMID:22800716 PMID:22960706 PMID:29079362 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpdu1 mannose-P-dolichol utilization defect 1 increases expression ISO T-2 Toxin results in increased expression of MPDU1 mRNA CTD PMID:31863870 NCBI chr10:54,374,719...54,380,301
Ensembl chr10:54,374,725...54,380,447
JBrowse link
G Mpo myeloperoxidase increases activity ISO T-2 Toxin results in increased activity of MPO protein CTD PMID:22960706 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mpst mercaptopyruvate sulfurtransferase affects expression EXP T-2 Toxin affects the expression of MPST protein CTD PMID:26141394 NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141
JBrowse link
G Mrap2 melanocortin 2 receptor accessory protein 2 decreases expression ISO T-2 Toxin results in decreased expression of MRAP2 mRNA CTD PMID:31863870 NCBI chr 8:88,088,293...88,144,636
Ensembl chr 8:88,088,272...88,143,886
JBrowse link
G Mrpl58 mitochondrial ribosomal protein L58 increases expression ISO T-2 Toxin results in increased expression of MRPL58 mRNA CTD PMID:31863870 NCBI chr10:100,646,374...100,652,871
Ensembl chr10:100,646,216...100,652,871
JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C increases expression ISO T-2 Toxin results in increased expression of MRPS18C mRNA CTD PMID:31863870 NCBI chr14:8,812,301...8,818,538
Ensembl chr14:8,791,330...8,818,516
JBrowse link
G Mrps22 mitochondrial ribosomal protein S22 increases expression ISO T-2 Toxin results in increased expression of MRPS22 mRNA CTD PMID:31863870 NCBI chr 8:99,184,110...99,197,278
Ensembl chr 8:99,184,109...99,197,291
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 affects expression EXP T-2 Toxin affects the expression of ATP6 mRNA CTD PMID:29870751 NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 increases expression EXP T-2 Toxin results in increased expression of ATP8 mRNA CTD PMID:29870751 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression EXP T-2 Toxin results in increased expression of COX1 mRNA CTD PMID:29870751 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II increases expression EXP T-2 Toxin results in increased expression of COX2 mRNA CTD PMID:29870751 NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III increases expression EXP T-2 Toxin results in increased expression of COX3 mRNA CTD PMID:29870751 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression EXP T-2 Toxin results in decreased expression of CYTB mRNA CTD PMID:29870751 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 increases expression EXP T-2 Toxin results in increased expression of ND3 mRNA CTD PMID:29870751 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 increases expression EXP T-2 Toxin results in increased expression of ND5 mRNA CTD PMID:29870751 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 increases expression EXP T-2 Toxin results in increased expression of ND6 mRNA CTD PMID:29870751 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression EXP
ISO
T-2 Toxin results in decreased expression of MTHFD2 mRNA CTD PMID:26141394 PMID:31863870 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mtor mechanistic target of rapamycin kinase affects expression EXP T-2 Toxin affects the expression of MTOR protein CTD PMID:29413859 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mtpn myotrophin affects expression EXP T-2 Toxin affects the expression of MTPN protein CTD PMID:26141394 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions
decreases expression
ISO ERN1 protein promotes the reaction [T-2 Toxin results in decreased expression of MUC2 protein]; ERN2 protein inhibits the reaction [T-2 Toxin results in decreased expression of MUC2 protein] CTD PMID:31170431 NCBI chr 1:196,796,257...196,831,740 JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 decreases expression ISO T-2 Toxin results in decreased expression of NANOS1 mRNA CTD PMID:31863870 NCBI chr 1:259,897,659...259,901,501
Ensembl chr 1:259,897,939...259,898,730
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression EXP T-2 Toxin results in decreased expression of NARS1 mRNA CTD PMID:26141394 NCBI chr18:57,989,308...58,005,639
Ensembl chr18:57,989,308...58,005,622
JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 increases expression EXP T-2 Toxin results in increased expression of NDUFAF1 mRNA CTD PMID:29870751 NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212
JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 increases expression EXP T-2 Toxin results in increased expression of NDUFAF2 mRNA CTD PMID:29870751 NCBI chr 2:39,535,680...39,647,378
Ensembl chr 2:39,535,689...39,647,316
JBrowse link
G Ndufaf3 NADH:ubiquinone oxidoreductase complex assembly factor 3 increases expression EXP T-2 Toxin results in increased expression of NDUFAF3 mRNA CTD PMID:29870751 NCBI chr 8:109,261,362...109,263,194
Ensembl chr 8:109,261,363...109,263,194
JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 increases expression EXP T-2 Toxin results in increased expression of NDUFAF4 mRNA CTD PMID:29870751 NCBI chr 5:38,605,169...38,610,341
Ensembl chr 5:38,605,153...38,610,336
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 increases expression EXP T-2 Toxin results in increased expression of NDUFS1 mRNA CTD PMID:29870751 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 affects expression
increases expression
EXP T-2 Toxin affects the expression of NDUFS3 protein
T-2 Toxin results in increased expression of NDUFS3 mRNA
CTD PMID:26141394 PMID:29870751 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 increases expression EXP T-2 Toxin results in increased expression of NDUFS4 mRNA CTD PMID:29870751 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 decreases expression EXP T-2 Toxin results in decreased expression of NDUFS5 mRNA CTD PMID:29870751 NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 increases expression EXP T-2 Toxin results in increased expression of NDUFS6 mRNA CTD PMID:29870751 NCBI chr 2:27,201,713...27,202,126
Ensembl chr 2:27,201,713...27,202,258
JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 increases expression EXP T-2 Toxin results in increased expression of NDUFS7 mRNA CTD PMID:29870751 NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 increases expression EXP T-2 Toxin results in increased expression of NDUFS8 mRNA CTD PMID:29870751 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 increases expression EXP T-2 Toxin results in increased expression of NDUFV1 mRNA CTD PMID:29870751 NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 increases expression EXP T-2 Toxin results in increased expression of NDUFV2 mRNA CTD PMID:29870751 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression EXP T-2 Toxin results in increased expression of NDUFV3 mRNA CTD PMID:29870751 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression
increases expression
multiple interactions
ISO
EXP
T-2 Toxin results in decreased expression of NFE2L2 mRNA; T-2 Toxin results in decreased expression of NFE2L2 protein
T-2 Toxin results in increased expression of NFE2L2 mRNA; T-2 Toxin results in increased expression of NFE2L2 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein]
CTD PMID:20854872 PMID:29432840 PMID:29870751 PMID:33508416 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO BAY 11-7085 inhibits the reaction [T-2 Toxin results in decreased expression of and results in increased degradation of NFKBIA protein]; T-2 Toxin results in increased degradation of and results in decreased expression of NFKBIA protein CTD PMID:22800716 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbil1 NFKB inhibitor like 1 increases expression EXP T-2 Toxin results in increased expression of NFKBIL1 mRNA CTD PMID:26141394 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616
JBrowse link
G Nfrkb nuclear factor related to kappa B binding protein increases expression EXP T-2 Toxin results in increased expression of NFRKB mRNA CTD PMID:26141394 NCBI chr 8:29,831,802...29,863,360
Ensembl chr 8:29,831,812...29,863,359
JBrowse link
G Niban1 niban apoptosis regulator 1 decreases expression ISO T-2 Toxin results in decreased expression of NIBAN1 mRNA CTD PMID:31863870 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP T-2 Toxin affects the expression of NME2 protein CTD PMID:26141394 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nol9 nucleolar protein 9 increases expression ISO T-2 Toxin results in increased expression of NOL9 mRNA CTD PMID:31863870 NCBI chr 5:162,546,522...162,566,625
Ensembl chr 5:162,546,541...162,566,191
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO T-2 Toxin results in increased expression of NOS2 mRNA CTD PMID:21112371 PMID:22960706 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 decreases expression ISO T-2 Toxin results in decreased expression of NOS3 mRNA CTD PMID:22960706 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Notch1 notch receptor 1 increases expression EXP T-2 Toxin results in increased expression of NOTCH1 mRNA CTD PMID:26141394 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Npm1 nucleophosmin 1 affects expression EXP T-2 Toxin affects the expression of NPM1 protein CTD PMID:26141394 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nptxr neuronal pentraxin receptor decreases expression EXP T-2 Toxin results in decreased expression of NPTXR mRNA CTD PMID:26141394 NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
increases expression
ISO
EXP
T-2 Toxin results in decreased expression of NQO1 mRNA
T-2 Toxin results in increased expression of NQO1 mRNA
CTD PMID:20854872 PMID:26141394 PMID:33508416 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression ISO T-2 Toxin results in decreased expression of NR0B1 mRNA CTD PMID:22982764 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO T-2 Toxin results in decreased expression of NR4A1 mRNA CTD PMID:31863870 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression ISO T-2 Toxin results in decreased expression of NR5A1 mRNA CTD PMID:22982764 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
JBrowse link
G Nrf1 nuclear respiratory factor 1 decreases expression
multiple interactions
affects expression
ISO
EXP
T-2 Toxin results in decreased expression of NRF1 protein
T-2 Toxin promotes the reaction [NRF1 protein binds to CYP1A1 promoter]
T-2 Toxin affects the expression of NRF1 mRNA
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of NRF1 protein]
CTD PMID:27363784 PMID:29870751 PMID:31470059 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Nrip3 nuclear receptor interacting protein 3 increases expression ISO T-2 Toxin results in increased expression of NRIP3 mRNA CTD PMID:31863870 NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 decreases expression ISO T-2 Toxin results in decreased expression of NTRK2 mRNA CTD PMID:31863870 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Nucb1 nucleobindin 1 affects expression EXP T-2 Toxin affects the expression of NUCB1 protein CTD PMID:26141394 NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220
JBrowse link
G Nucb2 nucleobindin 2 decreases expression ISO T-2 Toxin results in decreased expression of NUCB2 mRNA CTD PMID:31863870 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
JBrowse link
G Nup43 nucleoporin 43 increases expression EXP T-2 Toxin results in increased expression of NUP43 mRNA CTD PMID:26141394 NCBI chr 1:2,144,427...2,157,887
Ensembl chr 1:2,148,043...2,158,186
JBrowse link
G Oat ornithine aminotransferase affects expression EXP T-2 Toxin affects the expression of OAT protein CTD PMID:26141394 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Ocln occludin multiple interactions
decreases expression
ISO illite inhibits the reaction [T-2 Toxin results in decreased expression of OCLN mRNA]
T-2 Toxin results in decreased expression of OCLN mRNA; T-2 Toxin results in decreased expression of OCLN protein
CTD PMID:27153755 PMID:31170431 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 decreases expression ISO T-2 Toxin results in decreased expression of OSTM1 mRNA CTD PMID:31863870 NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta affects expression EXP T-2 Toxin affects the expression of P4HB protein CTD PMID:26141394 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pa2g4 proliferation-associated 2G4 affects expression EXP T-2 Toxin affects the expression of PA2G4 protein CTD PMID:26141394 NCBI chr 7:984,795...992,264
Ensembl chr 7:983,971...992,331
JBrowse link
G Park7 Parkinsonism associated deglycase affects expression EXP T-2 Toxin affects the expression of PARK7 protein CTD PMID:26141394 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO T-2 Toxin results in increased expression of PARP1 protein CTD PMID:29432840 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax6 paired box 6 increases expression ISO T-2 Toxin results in increased expression of PAX6 mRNA CTD PMID:26314264 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression ISO T-2 Toxin results in decreased expression of PCK2 mRNA CTD PMID:31863870 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pcna proliferating cell nuclear antigen affects expression EXP T-2 Toxin affects the expression of PCNA protein CTD PMID:26141394 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 decreases expression ISO T-2 Toxin results in decreased expression of PCSK5 mRNA CTD PMID:31863870 NCBI chr 1:214,837,847...215,267,626
Ensembl chr 1:214,837,927...215,267,600
JBrowse link
G Pcyox1l prenylcysteine oxidase 1 like decreases expression ISO T-2 Toxin results in decreased expression of PCYOX1L mRNA CTD PMID:31863870 NCBI chr18:55,150,637...55,161,334
Ensembl chr18:55,150,650...55,161,327
JBrowse link
G Pdcd10 programmed cell death 10 affects expression EXP T-2 Toxin affects the expression of PDCD10 protein CTD PMID:26141394 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018
JBrowse link
G Pdcd4 programmed cell death 4 increases expression EXP T-2 Toxin results in increased expression of PDCD4 mRNA CTD PMID:26141394 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Pdcd7 programmed cell death 7 increases expression EXP T-2 Toxin results in increased expression of PDCD7 mRNA CTD PMID:26141394 NCBI chr 8:65,862,604...65,877,333
Ensembl chr 8:65,862,387...65,877,333
JBrowse link
G Pde10a phosphodiesterase 10A decreases expression EXP T-2 Toxin results in decreased expression of PDE10A mRNA CTD PMID:26141394 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563
JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like decreases expression ISO T-2 Toxin results in decreased expression of PDGFRL mRNA CTD PMID:31863870 NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta affects expression EXP T-2 Toxin affects the expression of PDHB protein CTD PMID:26141394 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP T-2 Toxin affects the expression of PDIA3 protein CTD PMID:26141394 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO T-2 Toxin results in decreased expression of PDIA4 mRNA CTD PMID:31863870 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP T-2 Toxin results in decreased expression of PDLIM1 mRNA CTD PMID:26141394 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 increases expression EXP T-2 Toxin results in increased expression of PDRG1 mRNA CTD PMID:26141394 NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858
Ensembl chr 3:141,476,501...141,483,858
JBrowse link
G Pfn1 profilin 1 affects expression EXP T-2 Toxin affects the expression of PFN1 protein CTD PMID:26141394 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression EXP T-2 Toxin affects the expression of PGAM1 protein CTD PMID:26141394 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgk1 phosphoglycerate kinase 1 affects expression EXP T-2 Toxin affects the expression of PGK1 protein CTD PMID:26141394 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pgls 6-phosphogluconolactonase affects expression EXP T-2 Toxin affects the expression of PGLS protein CTD PMID:26141394 NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,300,317...18,305,803
JBrowse link
G Pgr progesterone receptor multiple interactions ISO T-2 Toxin inhibits the reaction [[CGA protein co-treated with FSHB protein] results in increased expression of PGR mRNA] CTD PMID:30951242 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phb1 prohibitin 1 affects expression
increases expression
EXP
ISO
T-2 Toxin affects the expression of PHB protein
T-2 Toxin results in increased expression of PHB mRNA
CTD PMID:26141394 PMID:31863870 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 decreases expression EXP T-2 Toxin results in decreased expression of PIK3R2 mRNA CTD PMID:26141394 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions
increases expression
EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of PINK1 protein]; NFE2L2 protein affects the reaction [T-2 Toxin results in increased expression of PINK1 protein]
T-2 Toxin results in increased expression of PINK1 mRNA; T-2 Toxin results in increased expression of PINK1 protein
CTD PMID:29870751 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression EXP T-2 Toxin results in decreased expression of PKIB mRNA CTD PMID:26141394 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
JBrowse link
G Pkig cAMP-dependent protein kinase inhibitor gamma affects expression EXP T-2 Toxin affects the expression of PKIG protein CTD PMID:26141394 NCBI chr 3:152,330,486...152,398,085
Ensembl chr 3:152,366,041...152,398,082
JBrowse link
G Pkm pyruvate kinase M1/2 affects expression EXP T-2 Toxin affects the expression of PKM protein CTD PMID:26141394 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Plxna4 plexin A4 decreases expression ISO T-2 Toxin results in decreased expression of PLXNA4 mRNA CTD PMID:31863870 NCBI chr 4:60,720,246...61,162,206
Ensembl chr 4:60,720,255...61,162,206
JBrowse link
G Pou1f1 POU class 1 homeobox 1 increases expression EXP T-2 Toxin results in increased expression of POU1F1 mRNA CTD PMID:26141394 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP T-2 Toxin results in increased expression of PPARG mRNA CTD PMID:26141394 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression
increases expression
multiple interactions
ISO
EXP
T-2 Toxin results in decreased expression of PPARGC1A protein
T-2 Toxin results in increased expression of PPARGC1A mRNA
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of PPARGC1A protein]
CTD PMID:27363784 PMID:29870751 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases expression EXP T-2 Toxin results in increased expression of PPARGC1B mRNA CTD PMID:29870751 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase increases expression ISO T-2 Toxin results in increased expression of PPCS mRNA CTD PMID:31863870 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
JBrowse link
G Ppia peptidylprolyl isomerase A affects expression EXP T-2 Toxin affects the expression of PPIA protein CTD PMID:26141394 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Pprc1 PPARG related coactivator 1 increases expression EXP T-2 Toxin results in increased expression of PPRC1 mRNA CTD PMID:29870751 NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587
JBrowse link
G Prcp prolylcarboxypeptidase decreases expression ISO T-2 Toxin results in decreased expression of PRCP mRNA CTD PMID:31863870 NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530
JBrowse link
G Prdx3 peroxiredoxin 3 affects expression EXP T-2 Toxin affects the expression of PRDX3 protein CTD PMID:26141394 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Prdx4 peroxiredoxin 4 affects expression EXP T-2 Toxin affects the expression of PRDX4 protein CTD PMID:26141394 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066
JBrowse link
G Prelp proline and arginine rich end leucine rich repeat protein decreases expression ISO T-2 Toxin results in decreased expression of PRELP mRNA CTD PMID:31863870 NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270
JBrowse link
G Prickle2 prickle planar cell polarity protein 2 increases expression ISO T-2 Toxin results in increased expression of PRICKLE2 mRNA CTD PMID:31863870 NCBI chr 4:124,869,552...125,214,862
Ensembl chr 4:124,869,552...125,214,824
JBrowse link
G Prkcb protein kinase C, beta decreases expression EXP T-2 Toxin results in decreased expression of PRKCB mRNA CTD PMID:26141394 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcz protein kinase C, zeta decreases expression EXP T-2 Toxin results in decreased expression of PRKCZ mRNA CTD PMID:26141394 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase increases expression EXP T-2 Toxin results in increased expression of PRKN mRNA; T-2 Toxin results in increased expression of PRKN protein CTD PMID:29870751 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO T-2 Toxin results in decreased expression of PSAT1 mRNA CTD PMID:31863870 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psma4 proteasome 20S subunit alpha 4 affects expression EXP T-2 Toxin affects the expression of PSMA4 protein CTD PMID:26141394 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 affects expression EXP T-2 Toxin affects the expression of PSMA6 protein CTD PMID:26141394 NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 affects expression EXP T-2 Toxin affects the expression of PSMB3 protein CTD PMID:26141394 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
JBrowse link
G Psmb7 proteasome 20S subunit beta 7 affects expression EXP T-2 Toxin affects the expression of PSMB7 protein CTD PMID:26141394 NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937
JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 increases expression EXP T-2 Toxin results in increased expression of PSMD9 mRNA CTD PMID:26141394 NCBI chr12:33,337,182...33,357,468 JBrowse link
G Ptgis prostaglandin I2 synthase decreases expression ISO T-2 Toxin results in decreased expression of PTGIS mRNA CTD PMID:31863870 NCBI chr 3:155,928,564...155,964,228 JBrowse link
G Pyy peptide YY increases expression ISO T-2 Toxin results in increased expression of PYY protein alternative form CTD PMID:29689362 NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
JBrowse link
G Qsox1 quiescin sulfhydryl oxidase 1 decreases expression EXP T-2 Toxin results in decreased expression of QSOX1 mRNA CTD PMID:26141394 NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459
JBrowse link
G Qsox2 quiescin sulfhydryl oxidase 2 decreases expression EXP T-2 Toxin results in decreased expression of QSOX2 mRNA CTD PMID:26141394 NCBI chr 3:9,034,994...9,064,649
Ensembl chr 3:9,034,994...9,064,664
JBrowse link
G Rab20 RAB20, member RAS oncogene family increases expression ISO T-2 Toxin results in increased expression of RAB20 mRNA CTD PMID:31863870 NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529
JBrowse link
G Rab25 RAB25, member RAS oncogene family increases expression EXP T-2 Toxin results in increased expression of RAB25 mRNA CTD PMID:26141394 NCBI chr 2:174,000,323...174,006,422
Ensembl chr 2:174,000,323...174,006,422
JBrowse link
G Rab27a RAB27A, member RAS oncogene family decreases expression EXP T-2 Toxin results in decreased expression of RAB27A mRNA CTD PMID:26141394 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Ramp1 receptor activity modifying protein 1 decreases expression ISO T-2 Toxin results in decreased expression of RAMP1 mRNA CTD PMID:31863870 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
JBrowse link
G Ranbp1 RAN binding protein 1 affects expression EXP T-2 Toxin affects the expression of RANBP1 protein CTD PMID:26141394 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
JBrowse link
G Rasal3 RAS protein activator like 3 increases expression EXP T-2 Toxin results in increased expression of RASAL3 mRNA CTD PMID:26141394 NCBI chr 7:11,396,090...11,411,349
Ensembl chr 7:11,396,090...11,411,465
JBrowse link
G Rasd1 ras related dexamethasone induced 1 decreases expression EXP T-2 Toxin results in decreased expression of RASD1 mRNA CTD PMID:26141394 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Rassf1 Ras association domain family member 1 increases expression EXP T-2 Toxin results in increased expression of RASSF1 mRNA CTD PMID:26141394 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164
JBrowse link
G Rassf4 Ras association domain family member 4 decreases expression EXP T-2 Toxin results in decreased expression of RASSF4 mRNA CTD PMID:26141394 NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation
decreases expression
EXP T-2 Toxin results in decreased phosphorylation of RB1 protein
T-2 Toxin results in decreased expression of RB1 mRNA
CTD PMID:29567467 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbks ribokinase increases expression EXP T-2 Toxin results in increased expression of RBKS mRNA CTD PMID:26141394 NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290
JBrowse link
G Rbpms2 RNA binding protein, mRNA processing factor 2 decreases expression ISO T-2 Toxin results in decreased expression of RBPMS2 mRNA CTD PMID:31863870 NCBI chr 8:66,153,169...66,184,278
Ensembl chr 8:66,153,593...66,184,268
JBrowse link
G Rcn1 reticulocalbin 1 affects expression EXP T-2 Toxin affects the expression of RCN1 protein CTD PMID:26141394 NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
EXP T-2 Toxin promotes the reaction [RELA protein binds to AKNA promoter]
T-2 Toxin affects the localization of RELA protein modified form
CTD PMID:29079362 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Reln reelin increases expression ISO T-2 Toxin results in increased expression of RELN mRNA CTD PMID:26314264 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G RGD1307947 similar to RIKEN cDNA C430008C19 increases expression ISO T-2 Toxin results in increased expression of C12ORF29 mRNA CTD PMID:31863870 NCBI chr 7:35,396,876...35,408,633
Ensembl chr 7:35,397,995...35,409,600
JBrowse link
G RGD1564308 similar to LOC495042 protein increases expression ISO T-2 Toxin results in increased expression of C4ORF47 mRNA CTD PMID:31863870 NCBI chr16:46,291,075...46,315,616
Ensembl chr16:46,291,311...46,315,625
JBrowse link
G Rgs12 regulator of G-protein signaling 12 decreases expression EXP T-2 Toxin results in decreased expression of RGS12 mRNA CTD PMID:26141394 NCBI chr14:75,715,925...75,824,012
Ensembl chr14:75,715,934...75,794,596
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP T-2 Toxin results in increased expression of RGS2 mRNA CTD PMID:26141394 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression EXP T-2 Toxin results in increased expression of RGS4 mRNA CTD PMID:26141394 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rheb Ras homolog, mTORC1 binding increases expression
multiple interactions
ISO T-2 Toxin results in increased expression of RHEB mRNA; T-2 Toxin results in increased expression of RHEB protein
MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB mRNA]; MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of RHEB protein]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of IL6 mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]
CTD PMID:32240701 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
JBrowse link
G Rhoh ras homolog family member H increases expression EXP T-2 Toxin results in increased expression of RHOH mRNA CTD PMID:26141394 NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369
JBrowse link
G Rpia ribose 5-phosphate isomerase A decreases expression EXP T-2 Toxin results in decreased expression of RPIA mRNA CTD PMID:26141394 NCBI chr 4:102,723,712...102,749,374
Ensembl chr 4:102,723,712...102,749,355
JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 affects expression EXP T-2 Toxin affects the expression of RPLP2 protein CTD PMID:26141394 NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645
JBrowse link
G Rpn2 ribophorin II decreases expression ISO T-2 Toxin results in decreased expression of RPN2 mRNA CTD PMID:31863870 NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
JBrowse link
G Rps21-ps1 ribosomal protein S21, pseudogene 1 affects expression EXP T-2 Toxin affects the expression of RPS21 protein CTD PMID:26141394 NCBI chr 5:153,387,133...153,387,476 JBrowse link
G Rpsa ribosomal protein SA affects expression EXP T-2 Toxin affects the expression of RPSA protein CTD PMID:26141394 NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 increases expression ISO T-2 Toxin results in increased expression of RUVBL1 mRNA CTD PMID:31863870 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 affects expression
increases expression
EXP
ISO
T-2 Toxin affects the expression of RUVBL2 protein
T-2 Toxin results in increased expression of RUVBL2 mRNA
CTD PMID:26141394 PMID:31863870 NCBI chr 1:95,902,014...95,915,364
Ensembl chr 1:95,901,701...95,915,342
JBrowse link
G Safb scaffold attachment factor B increases expression EXP T-2 Toxin results in increased expression of SAFB mRNA CTD PMID:26141394 NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644
JBrowse link
G Scpep1 serine carboxypeptidase 1 decreases expression ISO T-2 Toxin results in decreased expression of SCPEP1 mRNA CTD PMID:31863870 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A increases expression EXP T-2 Toxin results in increased expression of SDHA mRNA CTD PMID:29870751 NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B increases expression EXP T-2 Toxin results in increased expression of SDHB mRNA CTD PMID:29870751 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
JBrowse link
G Sema3f semaphorin 3F decreases expression EXP T-2 Toxin results in decreased expression of SEMA3F mRNA CTD PMID:26141394 NCBI chr 8:108,357,629...108,387,083
Ensembl chr 8:108,357,629...108,387,083
JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N decreases expression ISO T-2 Toxin results in decreased expression of SERPINA3 mRNA CTD PMID:31863870 NCBI chr 6:123,323,632...123,331,166 JBrowse link
G Serpine2 serpin family E member 2 decreases expression EXP T-2 Toxin results in decreased expression of SERPINE2 mRNA CTD PMID:26141394 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Set SET nuclear proto-oncogene affects expression EXP T-2 Toxin affects the expression of SET protein CTD PMID:26141394 NCBI chr19:53,561,262...53,562,780
Ensembl chr19:53,561,190...53,563,819
JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 increases expression EXP T-2 Toxin results in increased expression of SETDB1 mRNA CTD PMID:26141394 NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506
JBrowse link
G Sgms1 sphingomyelin synthase 1 decreases expression EXP T-2 Toxin results in decreased expression of SGMS1 mRNA CTD PMID:26141394 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603
JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 affects expression EXP T-2 Toxin affects the expression of SH3GL1 protein CTD PMID:26141394 NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
JBrowse link
G Skp1 S-phase kinase-associated protein 1 affects expression EXP T-2 Toxin affects the expression of SKP1 protein CTD PMID:26141394 NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388
JBrowse link
G Slc17a5 solute carrier family 17 member 5 decreases expression ISO T-2 Toxin results in decreased expression of SLC17A5 mRNA CTD PMID:31863870 NCBI chr 8:79,394,416...79,429,387 JBrowse link
G Slc17a6 solute carrier family 17 member 6 decreases expression ISO T-2 Toxin results in decreased expression of SLC17A6 mRNA CTD PMID:26314264 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO T-2 Toxin results in decreased expression of SLC1A5 mRNA CTD PMID:31863870 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952
JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression EXP T-2 Toxin results in increased expression of SLC27A5 mRNA CTD PMID:26141394 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
JBrowse link
G Slc29a4 solute carrier family 29 member 4 decreases expression EXP T-2 Toxin results in decreased expression of SLC29A4 mRNA CTD PMID:26141394 NCBI chr12:11,853,540...11,884,660
Ensembl chr12:11,853,540...11,874,834
JBrowse link
G Slc35g1 solute carrier family 35, member G1 decreases expression ISO T-2 Toxin results in decreased expression of SLC35G1 mRNA CTD PMID:31863870 NCBI chr 1:236,163,665...236,170,099
Ensembl chr 1:236,163,175...236,170,262
JBrowse link
G Slc37a3 solute carrier family 37, member 3 decreases expression ISO T-2 Toxin results in decreased expression of SLC37A3 mRNA CTD PMID:31863870 NCBI chr 4:68,109,314...68,153,590
Ensembl chr 4:68,081,939...68,153,568
JBrowse link
G Slc38a1 solute carrier family 38, member 1 decreases expression ISO T-2 Toxin results in decreased expression of SLC38A1 mRNA CTD PMID:31863870 NCBI chr 7:127,733,230...127,802,541
Ensembl chr 7:127,738,226...127,802,218
JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression ISO T-2 Toxin results in decreased expression of SLC7A2 mRNA CTD PMID:31863870 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784
JBrowse link
G Slit1 slit guidance ligand 1 decreases expression EXP T-2 Toxin results in decreased expression of SLIT1 mRNA CTD PMID:26141394 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
JBrowse link
G Smoc1 SPARC related modular calcium binding 1 decreases expression ISO T-2 Toxin results in decreased expression of SMOC1 mRNA CTD PMID:31863870 NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699
JBrowse link
G Sms spermine synthase increases expression ISO T-2 Toxin results in increased expression of SMS mRNA CTD PMID:31863870 NCBI chr  X:37,516,949...37,572,657
Ensembl chr  X:37,516,931...37,570,822
JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F affects expression EXP T-2 Toxin affects the expression of SNRPF protein CTD PMID:26141394 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression
multiple interactions
ISO T-2 Toxin results in increased expression of SOCS1 mRNA
MIR155 mRNA inhibits the reaction [T-2 Toxin results in increased expression of SOCS1 mRNA]
CTD PMID:32240701 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
affects expression
ISO
EXP
T-2 Toxin results in increased expression of SOD1 mRNA
T-2 Toxin affects the expression of SOD1 protein
CTD PMID:26138683 PMID:26141394 PMID:33508416 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
increases expression
EXP
ISO
T-2 Toxin results in decreased expression of SOD2 mRNA
T-2 Toxin results in increased expression of SOD2 mRNA
CTD PMID:26141394 PMID:29870751 PMID:30091165 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO T-2 Toxin promotes the reaction [SP1 protein binds to CYP1A1 promoter] CTD PMID:31470059 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Spata5 spermatogenesis associated 5 increases expression EXP T-2 Toxin results in increased expression of SPATA5 mRNA CTD PMID:26141394 NCBI chr 2:120,306,412...120,497,707
Ensembl chr 2:120,306,412...120,497,705
JBrowse link
G Spcs3 signal peptidase complex subunit 3 decreases expression ISO T-2 Toxin results in decreased expression of SPCS3 mRNA CTD PMID:31863870 NCBI chr16:37,305,358...37,310,792
Ensembl chr16:37,305,305...37,331,746
JBrowse link
G Srfbp1 serum response factor binding protein 1 increases expression ISO T-2 Toxin results in increased expression of SRFBP1 mRNA CTD PMID:31863870 NCBI chr18:45,920,389...45,945,385
Ensembl chr18:45,920,446...45,942,515
JBrowse link
G Ssr3 signal sequence receptor subunit 3 decreases expression ISO T-2 Toxin results in decreased expression of SSR3 mRNA CTD PMID:31863870 NCBI chr 2:149,605,005...149,625,069
Ensembl chr 2:149,605,005...149,625,132
JBrowse link
G Sstr1 somatostatin receptor 1 decreases expression EXP T-2 Toxin results in decreased expression of SSTR1 mRNA CTD PMID:26141394 NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions
EXP
ISO
T-2 Toxin results in decreased expression of STAR mRNA; T-2 Toxin results in decreased expression of STAR protein
1-Methyl-3-isobutylxanthine inhibits the reaction [T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]]; T-2 Toxin inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA]; T-2 Toxin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA]
[T-2 Toxin co-treated with CGA protein] results in decreased activity of STAR protein; [T-2 Toxin co-treated with CGA protein] results in decreased expression of STAR mRNA
CTD PMID:25542145 PMID:25962641 PMID:30951242 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions
decreases expression
increases phosphorylation
increases expression
ISO
EXP
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein]
T-2 Toxin results in decreased expression of STAT1 mRNA
CTD PMID:22454431 PMID:26141394 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat2 signal transducer and activator of transcription 2 increases expression
decreases expression
ISO
EXP
T-2 Toxin results in increased expression of STAT2 mRNA
T-2 Toxin results in decreased expression of STAT2 mRNA
CTD PMID:22454431 PMID:26141394 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases expression
increases expression
increases phosphorylation
ISO
EXP
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]
T-2 Toxin results in decreased expression of STAT3 mRNA
CTD PMID:22454431 PMID:26141394 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stk4 serine/threonine kinase 4 decreases expression EXP T-2 Toxin results in decreased expression of STK4 mRNA CTD PMID:26141394 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link
G Stoml2 stomatin like 2 affects expression EXP T-2 Toxin affects the expression of STOML2 protein CTD PMID:26141394 NCBI chr 5:57,256,227...57,259,824
Ensembl chr 5:57,256,220...57,259,920
JBrowse link
G Sucnr1 succinate receptor 1 decreases expression EXP T-2 Toxin results in decreased expression of SUCNR1 mRNA CTD PMID:26141394 NCBI chr 2:144,219,066...144,230,568
Ensembl chr 2:144,219,122...144,230,034
JBrowse link
G Suox sulfite oxidase decreases expression EXP T-2 Toxin results in decreased expression of SUOX mRNA CTD PMID:26141394 NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
JBrowse link
G Sybu syntabulin increases expression
decreases expression
EXP
ISO
T-2 Toxin results in increased expression of SYBU mRNA
T-2 Toxin results in decreased expression of SYBU mRNA
CTD PMID:26141394 PMID:31863870 NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828
JBrowse link
G Syt11 synaptotagmin 11 decreases expression EXP T-2 Toxin results in decreased expression of SYT11 mRNA CTD PMID:26141394 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964
JBrowse link
G Syt17 synaptotagmin 17 decreases expression EXP T-2 Toxin results in decreased expression of SYT17 mRNA CTD PMID:26141394 NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960
JBrowse link
G Tac1 tachykinin, precursor 1 increases expression ISO T-2 Toxin results in increased expression of TAC1 protein CTD PMID:30336258 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Taldo1 transaldolase 1 affects expression EXP T-2 Toxin affects the expression of TALDO1 protein CTD PMID:26141394 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
JBrowse link
G Tatdn1 TatD DNase domain containing 1 increases expression ISO T-2 Toxin results in increased expression of TATDN1 mRNA CTD PMID:31863870 NCBI chr 7:90,451,025...90,481,000
Ensembl chr 7:90,441,079...90,481,133
JBrowse link
G Tbxa2r thromboxane A2 receptor increases expression EXP T-2 Toxin results in increased expression of TBXA2R mRNA CTD PMID:26141394 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
JBrowse link
G Tcp1 t-complex 1 affects expression EXP T-2 Toxin affects the expression of TCP1 protein CTD PMID:26141394 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Terc telomerase RNA component decreases expression EXP T-2 Toxin results in decreased expression of TERC mRNA CTD PMID:26141394 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions
increases expression
decreases expression
ISO
EXP
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [T-2 Toxin results in decreased expression of TFAM protein]
T-2 Toxin results in increased expression of TFAM mRNA
CTD PMID:27363784 PMID:29870751 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
JBrowse link
G Tfb1m transcription factor B1, mitochondrial affects expression EXP T-2 Toxin affects the expression of TFB1M mRNA CTD PMID:29870751 NCBI chr 1:44,115,240...44,161,737
Ensembl chr 1:44,119,166...44,161,709
JBrowse link
G Tfb2m transcription factor B2, mitochondrial affects expression EXP T-2 Toxin affects the expression of TFB2M mRNA CTD PMID:29870751 NCBI chr13:91,278,889...91,296,709
Ensembl chr13:91,278,898...91,296,657
JBrowse link
G Thbs1 thrombospondin 1 decreases expression ISO T-2 Toxin results in decreased expression of THBS1 mRNA CTD PMID:31863870 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thbs2 thrombospondin 2 decreases expression ISO T-2 Toxin results in decreased expression of THBS2 mRNA CTD PMID:31863870 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
JBrowse link
G Thbs3 thrombospondin 3 decreases expression ISO T-2 Toxin results in decreased expression of THBS3 mRNA CTD PMID:31863870 NCBI chr 2:174,621,788...174,633,594
Ensembl chr 2:174,621,812...174,633,594
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO T-2 Toxin inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] CTD PMID:31077750 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Timm50 translocase of inner mitochondrial membrane 50 increases expression ISO T-2 Toxin results in increased expression of TIMM50 mRNA CTD PMID:31863870 NCBI chr 1:83,574,872...83,582,769
Ensembl chr 1:83,556,757...83,582,793
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression
affects expression
multiple interactions
ISO T-2 Toxin results in decreased expression of TIMP1 protein
T-2 Toxin affects the expression of TIMP1 mRNA
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein]
CTD PMID:21112371 PMID:21144892 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases expression
affects expression
multiple interactions
ISO T-2 Toxin results in decreased expression of TIMP2 protein
T-2 Toxin affects the expression of TIMP2 mRNA
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP2 protein]
CTD PMID:21112371 PMID:21144892 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression ISO T-2 Toxin results in decreased expression of TIMP3 mRNA CTD PMID:31863870 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tkt transketolase affects expression EXP T-2 Toxin affects the expression of TKT protein CTD PMID:26141394 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tmem102 transmembrane protein 102 decreases expression EXP T-2 Toxin results in decreased expression of TMEM102 mRNA CTD PMID:26141394 NCBI chr10:54,523,901...54,525,999
Ensembl chr10:54,523,585...54,525,990
JBrowse link
G Tmem123 transmembrane protein 123 decreases expression EXP T-2 Toxin results in decreased expression of TMEM123 mRNA CTD PMID:26141394 NCBI chr 8:4,922,098...4,952,228
Ensembl chr 8:4,922,098...4,952,224
JBrowse link
G Tmem167a transmembrane protein 167A decreases expression ISO T-2 Toxin results in decreased expression of TMEM167A mRNA CTD PMID:31863870 NCBI chr 2:21,197,728...21,216,746
Ensembl chr 2:21,197,786...21,212,099
JBrowse link
G Tmem25 transmembrane protein 25 decreases expression ISO T-2 Toxin results in decreased expression of TMEM25 mRNA CTD PMID:31863870 NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:45,107,121...45,116,389
JBrowse link
G Tmem50b transmembrane protein 50B decreases expression ISO T-2 Toxin results in decreased expression of TMEM50B mRNA CTD PMID:31863870 NCBI chr11:30,804,835...30,837,675
Ensembl chr11:30,804,837...30,837,661
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases methylation
increases expression
ISO
EXP
Selenium promotes the reaction [T-2 Toxin results in increased expression of TNF protein]
T-2 Toxin results in decreased methylation of TNF promoter
Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of TNF promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]
T-2 Toxin results in increased expression of TNF mRNA; T-2 Toxin results in increased expression of TNF protein
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]; ATG3 protein affects the reaction [T-2 Toxin results in increased expression of TNF mRNA]; MIR155 mRNA promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]; RHEB protein promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA]
CTD PMID:18196609 PMID:21112371 PMID:22454431 PMID:22960706 PMID:29079362 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression EXP T-2 Toxin results in increased expression of TNFRSF12A mRNA CTD PMID:26141394 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tomm34 translocase of outer mitochondrial membrane 34 increases expression ISO T-2 Toxin results in increased expression of TOMM34 mRNA CTD PMID:31863870 NCBI chr 3:152,729,345...152,746,295
Ensembl chr 3:152,729,349...152,746,373
JBrowse link
G Tp53 tumor protein p53 increases expression EXP
ISO
T-2 Toxin results in increased expression of TP53 mRNA; T-2 Toxin results in increased expression of TP53 protein
T-2 Toxin results in increased expression of TRP53 mRNA; T-2 Toxin results in increased expression of TRP53 protein
CTD PMID:19524637 PMID:21296132 PMID:29432840 PMID:29567467 PMID:29870751 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpi1 triosephosphate isomerase 1 affects expression EXP T-2 Toxin affects the expression of TPI1 protein CTD PMID:26141394 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tpp1 tripeptidyl peptidase 1 decreases expression ISO T-2 Toxin results in decreased expression of TPP1 mRNA CTD PMID:31863870 NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129
JBrowse link
G Traf2 Tnf receptor-associated factor 2 increases expression EXP T-2 Toxin results in increased expression of TRAF2 mRNA CTD PMID:26141394 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Trap1 TNF receptor-associated protein 1 affects expression EXP T-2 Toxin affects the expression of TRAP1 protein CTD PMID:26141394 NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO T-2 Toxin results in decreased expression of TRIB3 mRNA CTD PMID:31863870 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Tspan8 tetraspanin 8 decreases expression ISO T-2 Toxin results in decreased expression of TSPAN8 mRNA CTD PMID:31863870 NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356
JBrowse link
G Ttr transthyretin multiple interactions ISO T-2 Toxin inhibits the reaction [Thyroxine binds to TTR protein] CTD PMID:31077750 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Tuba1c tubulin, alpha 1C affects expression EXP T-2 Toxin affects the expression of TUBA1C protein CTD PMID:26141394 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tubb5 tubulin, beta 5 class I affects expression EXP T-2 Toxin affects the expression of TUBB protein CTD PMID:26141394 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Tufm Tu translation elongation factor, mitochondrial affects expression EXP T-2 Toxin affects the expression of TUFM protein CTD PMID:26141394 NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression EXP T-2 Toxin affects the expression of UBE2N protein CTD PMID:26141394 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 affects expression EXP T-2 Toxin affects the expression of UCHL1 protein CTD PMID:26141394 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Ucp1 uncoupling protein 1 increases expression EXP T-2 Toxin results in increased expression of UCP1 mRNA CTD PMID:29870751 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852
JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP T-2 Toxin results in increased expression of UCP2 mRNA CTD PMID:29870751 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP T-2 Toxin results in increased expression of UCP3 mRNA CTD PMID:29870751 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Upf3a UPF3A, regulator of nonsense mediated mRNA decay increases expression EXP T-2 Toxin results in increased expression of UPF3A mRNA CTD PMID:26141394 NCBI chr16:75,757,442...75,768,478
Ensembl chr16:75,757,441...75,769,345
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 increases expression EXP T-2 Toxin results in increased expression of UQCRFS1 mRNA CTD PMID:29870751 NCBI chr17:33,977,908...33,982,478
Ensembl chr17:33,977,921...33,982,479
JBrowse link
G Vdac1 voltage-dependent anion channel 1 affects expression EXP T-2 Toxin affects the expression of VDAC1 protein CTD PMID:26141394 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 increases expression ISO T-2 Toxin results in increased expression of VEPH1 mRNA CTD PMID:31863870 NCBI chr 2:150,291,379...150,537,491
Ensembl chr 2:150,296,573...150,537,266
JBrowse link
G Vti1a vesicle transport through interaction with t-SNAREs 1A increases expression EXP T-2 Toxin results in increased expression of VTI1A mRNA CTD PMID:26141394 NCBI chr 1:254,356,343...254,661,854
Ensembl chr 1:254,356,429...254,661,852
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 decreases expression ISO T-2 Toxin results in decreased expression of WARS1 mRNA CTD PMID:31863870 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Wdr54 WD repeat domain 54 increases expression ISO T-2 Toxin results in increased expression of WDR54 mRNA CTD PMID:31863870 NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:115,654,968...115,661,562
JBrowse link
G Wdr74 WD repeat domain 74 increases expression ISO T-2 Toxin results in increased expression of WDR74 mRNA CTD PMID:31863870 NCBI chr 1:205,631,769...205,636,563
Ensembl chr 1:205,631,824...205,636,563
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 decreases expression ISO T-2 Toxin results in decreased expression of WIPI1 mRNA CTD PMID:31863870 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
JBrowse link
G Xbp1 X-box binding protein 1 increases expression
decreases expression
ISO T-2 Toxin results in increased expression of XBP1 protein alternative form
T-2 Toxin results in decreased expression of XBP1 mRNA
CTD PMID:31170431 PMID:31863870 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta affects expression EXP T-2 Toxin affects the expression of YWHAB protein CTD PMID:26141394 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon affects expression EXP T-2 Toxin affects the expression of YWHAE protein CTD PMID:26141394 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma affects expression EXP T-2 Toxin affects the expression of YWHAG protein CTD PMID:26141394 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta affects expression EXP T-2 Toxin affects the expression of YWHAQ protein CTD PMID:26141394 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
JBrowse link
G Zbtb21 zinc finger and BTB domain containing 21 increases expression ISO T-2 Toxin results in increased expression of ZBTB21 mRNA CTD PMID:31863870 NCBI chr11:37,311,860...37,327,040
Ensembl chr11:37,312,378...37,326,996
JBrowse link
G Zc3h8 zinc finger CCCH type containing 8 increases expression ISO T-2 Toxin results in increased expression of ZC3H8 mRNA CTD PMID:31863870 NCBI chr 3:116,176,779...116,193,752
Ensembl chr 3:116,176,798...116,193,787
JBrowse link
G Zfp422 zinc finger protein 422 increases expression ISO T-2 Toxin results in increased expression of ZNF22 mRNA CTD PMID:31863870 NCBI chr 4:149,885,805...149,893,287
Ensembl chr 4:149,885,600...149,893,257
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          apoptosis inducer 13312
            HT-2 toxin 588
              T-2 toxin 586
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        monocarboxylic acid 17622
                                          acetic acid 10862
                                            acetate ester 3879
                                              HT-2 toxin 588
                                                T-2 toxin 586
paths to the root