Predicted to enable cytokine activity. Involved in defense response to virus. Predicted to be located in extracellular space. Biomarker of osteoarthritis. Orthologous to human IFNA13 (interferon alpha 13); PARTICIPATES IN autoimmune thyroiditis pathway; autophagy pathway; cytokine mediated signaling pathway; INTERACTS WITH 2-acetamidofluorene; acrylamide; ammonium chloride.
IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA] more ...
IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of FLT1 protein], IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of RGS5 mRNA]
[Dacarbazine co-treated with IFNA1 protein] results in increased expression of CD38 protein, Dacarbazine promotes the reaction [IFNA1 protein results in increased expression of CD38 protein]
IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA] more ...
ruxolitinib inhibits the reaction [IFNA1 protein affects the localization of and results in increased phosphorylation of STAT1 protein], ruxolitinib inhibits the reaction [IFNA1 protein affects the localization of and results in increased phosphorylation of STAT2 protein]
ursodoxicoltaurine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 mRNA], ursodoxicoltaurine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 protein]
[Carbon Tetrachloride co-treated with Tamoxifen] affects the expression of IFNA1 mRNA, IFNA1 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]
tofacitinib inhibits the reaction [IFNA1 protein affects the localization of and results in increased phosphorylation of STAT1 protein], tofacitinib inhibits the reaction [IFNA1 protein affects the localization of and results in increased phosphorylation of STAT2 protein]
Effects of long-term postoperative interferon-alpha therapy on intrahepatic recurrence after resection of hepatitis C virus-related hepatocellular carcinoma. A randomized, controlled trial.
Downregulation of long noncoding RNA LOC101928134 inhibits the synovial hyperplasia and cartilage destruction of osteoarthritis rats through the activation of the Janus kinase/signal transducers and activators of transcription signaling pathway by upregulating IFNA1.