Gene: Lta (lymphotoxin alpha) Rattus norvegicus
Analyze
Symbol:
Lta
Name:
lymphotoxin alpha
Description:
Predicted to have cytokine activity and tumor necrosis factor receptor binding activity. Involved in several processes, including negative regulation of fibroblast proliferation; positive regulation of glial cell proliferation; and response to lipopolysaccharide. Localizes to the extracellular space. Biomarker of cystitis. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); glucose metabolism disease (multiple); leishmaniasis (multiple); and lung disease (multiple). Orthologous to human LTA (lymphotoxin alpha); PARTICIPATES IN interleukin-4 signaling pathway; cytokine mediated signaling pathway; type 1 diabetes mellitus pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
LT-alpha; lymphotoxin A; Lymphotoxin alpha (formerly tumor necrosis factor beta); Lymphotoxin alpha (formerly tumor necrosis factor, beta); lymphotoxin alpha (TNF superfamily, member 1); lymphotoxin-alpha; TNF-beta; Tnfb; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
LTA (lymphotoxin alpha) HGNC
Ensembl, HomoloGene, Inparanoid, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Lta (lymphotoxin A) HGNC
Treefam, OrthoMCL, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Lta (lymphotoxin alpha) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
LTA (lymphotoxin alpha) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
LTA (lymphotoxin alpha) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Lta (lymphotoxin alpha) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
LTA (lymphotoxin alpha) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Lta (lymphotoxin A)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
LTA (lymphotoxin alpha)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
tnfb (tumor necrosis factor b (TNF superfamily, member 2))
Alliance
DIOPT (Ensembl Compara, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
tnfa (tumor necrosis factor a (TNF superfamily, member 2))
Alliance
DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 20 4,851,889 - 4,854,677 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_5.0 20 6,932,260 - 6,935,077 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 20 3,657,842 - 3,659,848 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 20 3,658,068 - 3,660,075 (+) NCBI Celera 20 4,404,630 - 4,406,751 (-) NCBI Celera Cytogenetic Map 20 p12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
RGD Manual Annotations
adult respiratory distress syndrome ISO RGD:1345394 4143247 DNA:polymorhpism:blood: RGD allergic hypersensitivity disease ISO RGD:1345394 8548785 DNA:polymorphism, haplotype RGD allergic hypersensitivity disease ISO RGD:1345394 8548802 associated with Nasal Polyps RGD arteriosclerosis ISO RGD:733657 1581936 RGD asthma susceptibility ISO RGD:1345394 4143373 DNA:polymorphisms:promoter RGD asthma ISO RGD:1345394 4143371 DNA:polymorphism:intron RGD asthma susceptibility ISO RGD:1345394 4143370 DNA:polymorphism:intron RGD asthma no_association ISO RGD:1345394 4143254 DNA:polymorphism:intron RGD breast cancer susceptibility ISO RGD:1345394 8548791 DNA:SNP:intron RGD breast cancer susceptibility ISO RGD:1345394 8548786 DNA:polymorphism, haplotype: :252A>G (human) RGD Cachexia susceptibility ISO RGD:1345394 8548798 associated with Breast Neoplasms, DNA:polymorphism:intron:252G>A (human) RGD carotid artery disease ISO RGD:1345394 1581937 associated with Diabetes Mellitus, Non-Insulin-Dependent, DNA:polymorphism: :252A>G (human) RGD cerebral infarction ISO RGD:1345394 1580416 RGD cerebral malaria ISO RGD:733657 10449455 RGD chorioamnionitis severity ISO RGD:1345394 12904055 associated with Premature Birth, DNA:SNP:promoter:250G>A (human) RGD contact dermatitis ISO RGD:733657 8548819 RGD coronary artery disease ISO RGD:1345394 1580414 RGD cutaneous leishmaniasis no_association ISO RGD:1345394 8548800 DNA:SNP:intron:252A>G (human) RGD cystic fibrosis severity ISO RGD:1345394 6767553 DNA:polymorphism, haplotype: :252A>G (human) RGD cystitis IEP 6907118 mRNA:increased expression:urinary bladder RGD dermatitis herpetiformis ISO RGD:1345394 8548777 DNA:polymorphism RGD Diabetic Nephropathies ISO RGD:1345394 2313255 DNA:polymorphism RGD diabetic retinopathy no_association ISO RGD:1345394 8548772 associated with Diabetes Mellitus, Type 2, DNA:polymorphism:intron, exon:252A>G, 804C>A (human) RGD diabetic retinopathy susceptibility ISO RGD:1345394 8548797 associated with Diabetes Mellitus, Type 2, DNA:polymorphism: RGD endometrial cancer susceptibility ISO RGD:1345394 2313259 DNA:polymorphism: :252A>G, 804C>A (human) RGD Erythema Nodosum ISO RGD:1345394 8548773 associated with Sarcoidosis, DNA:polymorphism:intron RGD Experimental Autoimmune Encephalomyelitis IEP 1625038 mRNA:increased expression:spinal cord RGD Experimental Autoimmune Encephalomyelitis IEP 4143220 mRNA:increased expression:brain RGD Graves' disease ISO RGD:1345394 8548778 DNA:polymorphism RGD Graves' disease no_association ISO RGD:1345394 8548790 DNA:polymorphism RGD Herpes Simplex Encephalitis ISO RGD:733657 8548806 RGD hyperinsulinism ISO RGD:1345394 1625034 associated with Coronary Arteriosclerosis RGD hypertension no_association ISO RGD:1345394 1580415 RGD Hypertriglyceridemia susceptibility ISO RGD:1345394 1625036 associated with Diabetes Mellitus, Non-Insulin-Dependent RGD Hypertriglyceridemia no_association ISO RGD:1345394 1625035 DNA:polymorphism RGD Insulin Resistance no_association ISO RGD:1345394 1625035 DNA:polymorphism RGD lung non-small cell carcinoma ISO RGD:1345394 4143264 protein:increased expression:lung RGD malignant glioma treatment ISO RGD:1345394 1625042 RGD melanoma disease_progression ISO RGD:1345394 8548801 RGD mucocutaneous leishmaniasis ISO RGD:1345394 8548799 DNA:polymorphism:intron RGD myocardial infarction severity ISO RGD:1345394 8548841 DNA:SNP:exon:804C>A (p.T26N) (human) RGD myocardial infarction no_association ISO RGD:1345394 1581940 RGD myocardial infarction ISO RGD:1345394 1580417 RGD proliferative vitreoretinopathy ISO RGD:1345394 8548782 DNA:SNP, haplotype:CDS:rs2229094 (human) RGD psoriasis susceptibility ISO RGD:1345394 8548775 DNA:SNP:intron:IVS1 (human) RGD psoriatic arthritis treatment ISO RGD:1345394 8548821 RGD pulmonary sarcoidosis susceptibility ISO RGD:1345394 4143248 DNA:SNP:intron: RGD pulmonary tuberculosis susceptibility ISO RGD:1345394 4143234 DNA:polymorphism:intron:252G>A (human) RGD pustulosis of palm and sole ISO RGD:1345394 8548804 DNA:SNP:intron:IVS1 (human) RGD sinusitis susceptibility ISO RGD:1345394 4143260 DNA:polymorphism: : RGD Sjogren's syndrome ISO RGD:733657 8548776 RGD Sjogren's syndrome no_association ISO RGD:1345394 8548787 DNA:SNPs: :multiple (human) RGD Sjogren's syndrome susceptibility ISO RGD:1345394 8548787 DNA:SNP, haplotype:intron: (rs909253) (human) RGD Sjogren's syndrome ISO RGD:1345394 8548776 protein:increased expression:saliva, serum RGD Sudden Hearing Loss ISO RGD:1345394 8548795 DNA:polymorphism:intron:252A>G (human) RGD systemic scleroderma susceptibility ISO RGD:1345394 8548796 DNA:SNP:intron:252A>G (human) RGD Transplant Rejection treatment IMP 8548836 RGD Transplant Rejection IEP 8548835 RGD trichinosis ISO RGD:733657 8548805 RGD type 1 diabetes mellitus treatment ISO RGD:1345394 8548842 RGD type 1 diabetes mellitus susceptibility ISO RGD:1345394 2313253 DNA:SNP (human) RGD type 1 diabetes mellitus ISO RGD:1345394 2313263 RGD type 1 diabetes mellitus onset ISO RGD:1345394 2313264 protein:decreased expression:mononuclear cell RGD type 1 diabetes mellitus ISO RGD:1345394 2313262 DNA:polymorphism: :252A>G (human) RGD type 1 diabetes mellitus susceptibility ISO RGD:1345394 2313257 DNA:polymorphism: :249A>G (human) RGD type 2 diabetes mellitus onset ISO RGD:1345394 1625033 DNA:polymorphism: :p.T60N (human) RGD type 2 diabetes mellitus no_association ISO RGD:1345394 2313261 DNA:polymorphism: :p.T60N (human) RGD visceral leishmaniasis severity ISO RGD:1345394 8548784 DNA:polymorphisms RGD visceral leishmaniasis ISO RGD:733657 8548789 RGD
Imported Annotations - ClinVar
leprosy ISO RGD:1345394 8554872 ClinVar Annotator: match by synonym: Leprosy, early-onset, susceptibility to ClinVar PMID:15052269 , PMID:17353895 myocardial infarction ISO RGD:1345394 8554872 ClinVar Annotator: match by null ClinVar PMID:12426569 , PMID:15266304 myocardial infarction ISO RGD:1345394 8554872 ClinVar Annotator: match by null ClinVar PMID:12426569 more ... psoriatic arthritis ISO RGD:1345394 8554872 ClinVar Annotator: match by OMIM:607507 ClinVar PMID:12426569 more ...
Imported Annotations - CTD
coronary artery disease ISO RGD:1345394 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:15266304 hepatic encephalopathy ISO RGD:1345394 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:9696492 leprosy ISO RGD:1345394 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:17353895 malignant mesothelioma ISO RGD:1345394 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25162674 myocardial infarction ISO RGD:1345394 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12426569 , PMID:15129282 psoriatic arthritis ISO RGD:1345394 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12746914 Sepsis ISO RGD:1345394 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:22977509 Imported Annotations - OMIM
leprosy susceptibility ISO RGD:1345394 7240710 OMIM myocardial infarction susceptibility ISO RGD:1345394 7240710 OMIM psoriatic arthritis susceptibility ISO RGD:1345394 7240710 OMIM
(-)-demecolcine increases expression ISO RGD:1345394 6480464 Demecolcine results in increased expression of LTA mRNA CTD PMID:23649840 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression EXP 6480464 o, p'-DDT results in increased expression of LTA mRNA CTD PMID:22937105 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression EXP 6480464 o, p'-DDT analog results in decreased expression of LTA mRNA CTD PMID:22937105 1-nitropyrene decreases expression ISO RGD:1345394 6480464 1-nitropyrene results in decreased expression of LTA mRNA CTD PMID:19428942 17beta-estradiol increases expression ISO RGD:1345394 6480464 Estradiol results in increased expression of LTA mRNA CTD PMID:23373633 2,2',4,4',5,5'-hexachlorobiphenyl affects expression ISO RGD:1345394 6480464 2 more ... CTD PMID:20638727 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:733657 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:733657 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:733657 6480464 Tetrachlorodibenzodioxin results in increased expression of LTA mRNA CTD PMID:12167310 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of LTA mRNA CTD PMID:19520675 2,6-dichloroindophenol multiple interactions ISO RGD:1345394 6480464 [2, 6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of LTA mRNA CTD PMID:21034357 3-chloropropane-1,2-diol increases expression ISO RGD:1345394 6480464 alpha-Chlorohydrin results in increased expression of LTA mRNA CTD PMID:28070108 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine multiple interactions ISO RGD:733657 6480464 4-methyl-N1-(3-phenylpropyl)benzene-1, 2-diamine inhibits the reaction [Cisplatin results in increased expression of LTA mRNA] CTD PMID:26546572 acetylsalicylic acid affects response to substance ISO RGD:1345394 6480464 LTA gene SNP affects the susceptibility to Aspirin CTD PMID:16931544 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of LTA mRNA CTD PMID:16483693 amphibole asbestos increases expression ISO RGD:1345394 6480464 Asbestos, Amphibole results in increased expression of LTA protein CTD PMID:20855422 arsane multiple interactions ISO RGD:1345394 6480464 [Arsenic co-treated with Fluorides] results in decreased expression of LTA mRNA CTD PMID:19962721 arsane decreases expression ISO RGD:1345394 6480464 Arsenic results in decreased expression of LTA mRNA CTD PMID:19962721 arsenic atom multiple interactions ISO RGD:1345394 6480464 [Arsenic co-treated with Fluorides] results in decreased expression of LTA mRNA CTD PMID:19962721 arsenic atom decreases expression ISO RGD:1345394 6480464 Arsenic results in decreased expression of LTA mRNA CTD PMID:19962721 arsenic(3+) decreases expression ISO RGD:1345394 6480464 Arsenic results in decreased expression of LTA mRNA CTD PMID:19962721 arsenic(3+) multiple interactions ISO RGD:1345394 6480464 [Arsenic co-treated with Fluorides] results in decreased expression of LTA mRNA CTD PMID:19962721 asbestos increases expression ISO RGD:1345394 6480464 Asbestos results in increased expression of LTA mRNA CTD PMID:22398240 asperentin increases expression ISO RGD:733657 6480464 cladosporin results in increased expression of LTA mRNA CTD PMID:19818335 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of LTA mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:733657 6480464 [NR1H4 gene mutant form affects the susceptibility to bisphenol A] which results in decreased expression of LTA mRNA CTD PMID:30245210 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of LTA promoter CTD PMID:22457795 cisplatin multiple interactions ISO RGD:733657 6480464 4-methyl-N1-(3-phenylpropyl)benzene-1, 2-diamine inhibits the reaction [Cisplatin results in increased expression of LTA mRNA] CTD PMID:26546572 cisplatin decreases expression ISO RGD:1345394 6480464 Cisplatin results in decreased expression of LTA mRNA CTD PMID:27392435 cisplatin multiple interactions ISO RGD:1345394 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of LTA mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:733657 6480464 Cisplatin results in increased expression of LTA mRNA CTD PMID:26546572 cobalt atom multiple interactions EXP 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of LTA mRNA CTD PMID:22198552 cobalt dichloride multiple interactions ISO RGD:1345394 6480464 [Chromium Alloys co-treated with cobaltous chloride] results in increased expression of LTA mRNA CTD PMID:25281833 cobalt(2+) multiple interactions EXP 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of LTA mRNA CTD PMID:22198552 curcumin decreases expression ISO RGD:1345394 6480464 Curcumin results in decreased expression of LTA mRNA CTD PMID:16101141 curcumin multiple interactions ISO RGD:1345394 6480464 [arsenic trioxide co-treated with Curcumin] results in increased expression of LTA protein CTD PMID:27430728 curcumin increases expression ISO RGD:1345394 6480464 Curcumin results in increased expression of LTA mRNA CTD PMID:17198877 cyclosporin A multiple interactions ISO RGD:1345394 6480464 Cyclosporine inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of LTA protein] CTD PMID:1371491 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of LTA mRNA CTD PMID:25596134 deoxynivalenol increases expression ISO RGD:733657 6480464 deoxynivalenol results in increased expression of LTA mRNA CTD PMID:22968694 dextran sulfate increases expression ISO RGD:733657 6480464 Dextran Sulfate results in increased expression of LTA mRNA CTD PMID:20079348 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of LTA mRNA CTD PMID:18035473 furosemide affects expression EXP 6480464 Furosemide affects the expression of LTA mRNA CTD PMID:17497460 gemcitabine increases expression ISO RGD:1345394 6480464 gemcitabine results in increased expression of LTA protein CTD PMID:20531411 ibuprofen affects response to substance ISO RGD:1345394 6480464 LTA gene SNP affects the susceptibility to Ibuprofen CTD PMID:16931544 indometacin multiple interactions ISO RGD:1345394 6480464 Indomethacin inhibits the reaction [LTA protein results in increased expression of BIRC3 protein] more ... CTD PMID:17873517 iron atom multiple interactions EXP 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of LTA mRNA CTD PMID:22198552 iron(0) multiple interactions EXP 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of LTA mRNA CTD PMID:22198552 iron(2+) sulfate (anhydrous) increases expression ISO RGD:1345394 6480464 ferrous sulfate results in increased expression of LTA mRNA CTD PMID:21540303 iron(2+) sulfate (anhydrous) decreases expression ISO RGD:1345394 6480464 ferrous sulfate results in decreased expression of LTA mRNA CTD PMID:19428942 lead nitrate multiple interactions ISO RGD:733657 6480464 lead nitrate affects the reaction [LTA affects the expression of MT1 mRNA], lead nitrate affects the reaction [LTA affects the expression of MT2 mRNA] CTD PMID:11891201 lipopolysaccharide multiple interactions ISO RGD:1345394 6480464 [Acetaminophen co-treated with Lipopolysaccharides] affects the expression of LTA mRNA, [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of LTA mRNA CTD PMID:22777745 , PMID:31059760 lipopolysaccharide increases expression ISO RGD:1345394 6480464 Lipopolysaccharides results in increased expression of LTA mRNA CTD PMID:31059760 lipopolysaccharide increases expression ISO RGD:733657 6480464 Lipopolysaccharides results in increased expression of LTA mRNA, Lipopolysaccharides results in increased expression of LTA protein CTD PMID:12057914 more ... lipopolysaccharide multiple interactions ISO RGD:733657 6480464 3, 4-dihydroxybenzohydroxamic acid affects the reaction [Lipopolysaccharides results in increased expression of LTA mRNA] CTD PMID:25843059 mycophenolic acid increases expression ISO RGD:733657 6480464 Mycophenolic Acid results in increased expression of LTA mRNA CTD PMID:19818335 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:1345394 6480464 N more ... CTD PMID:12888634 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:733657 6480464 Ethylnitrosourea results in increased mutagenesis of LTA gene CTD PMID:18384745 nickel atom multiple interactions EXP 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of LTA mRNA, [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of LTA mRNA CTD PMID:22198552 ozone multiple interactions ISO RGD:733657 6480464 [[LTA gene mutant form co-treated with TNF gene mutant form co-treated with LTB gene mutant form] co-treated with Ozone] results in decreased expression of H2-EB1 mRNA more ... CTD PMID:20032013 ozone increases expression ISO RGD:733657 6480464 Ozone results in increased expression of LTA mRNA CTD PMID:20032013 ozone decreases response to substance ISO RGD:733657 6480464 LTA gene mutant form results in decreased susceptibility to Ozone CTD PMID:20032013 paracetamol increases expression ISO RGD:733657 6480464 Acetaminophen results in increased expression of LTA mRNA CTD PMID:12540782 paracetamol multiple interactions ISO RGD:1345394 6480464 [Acetaminophen co-treated with Lipopolysaccharides] affects the expression of LTA mRNA CTD PMID:31059760 paracetamol affects expression ISO RGD:1345394 6480464 Acetaminophen affects the expression of LTA mRNA CTD PMID:31059760 paracetamol multiple interactions ISO RGD:733657 6480464 O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1, 2-diolate inhibits the reaction [Acetaminophen results in increased expression of LTA mRNA] CTD PMID:12540782 paracetamol affects response to substance ISO RGD:1345394 6480464 LTA polymorphism affects the susceptibility to Acetaminophen CTD PMID:9696492 paraquat decreases expression ISO RGD:1345394 6480464 Paraquat results in decreased expression of LTA mRNA CTD PMID:18836921 potassium dichromate increases expression ISO RGD:1345394 6480464 Potassium Dichromate results in increased expression of LTA mRNA CTD PMID:18332044 progesterone increases expression ISO RGD:733657 6480464 Progesterone results in increased expression of LTA mRNA CTD PMID:21549006 resveratrol decreases expression ISO RGD:1345394 6480464 resveratrol results in decreased expression of LTA mRNA CTD PMID:23224687 rifaximin multiple interactions ISO RGD:1345394 6480464 [NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of LTA mRNA CTD PMID:22790967 silicon dioxide decreases expression ISO RGD:1345394 6480464 Silicon Dioxide results in decreased expression of LTA mRNA CTD PMID:19428942 sodium arsenite increases expression ISO RGD:1345394 6480464 sodium arsenite results in increased expression of LTA mRNA CTD PMID:21281968 sterigmatocystin increases expression ISO RGD:733657 6480464 Sterigmatocystin results in increased expression of LTA mRNA CTD PMID:19818335 tacrolimus hydrate multiple interactions ISO RGD:1345394 6480464 Tacrolimus inhibits the reaction [enterotoxin A, Staphylococcal results in increased expression of LTA protein] CTD PMID:1371491 toluene 2,4-diisocyanate multiple interactions ISO RGD:733657 6480464 TNF protein affects the reaction [Toluene 2, 4-Diisocyanate results in increased expression of LTA mRNA] CTD PMID:12356572 toluene 2,4-diisocyanate increases expression ISO RGD:733657 6480464 Toluene 2, 4-Diisocyanate results in increased expression of LTA mRNA CTD PMID:12356572 trichloroethene decreases expression ISO RGD:733657 6480464 Trichloroethylene results in decreased expression of LTA mRNA CTD PMID:22407948 troglitazone decreases expression ISO RGD:733657 6480464 troglitazone results in decreased expression of LTA mRNA CTD PMID:17569031 troglitazone increases expression ISO RGD:1345394 6480464 troglitazone results in increased expression of LTA mRNA CTD PMID:19631733 tungsten multiple interactions EXP 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of LTA mRNA, [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of LTA mRNA CTD PMID:22198552 tungsten(4+) multiple interactions EXP 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of LTA mRNA, [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of LTA mRNA CTD PMID:22198552 usnic acid multiple interactions ISO RGD:1345394 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of LTA mRNA CTD PMID:22777745 vincristine increases expression ISO RGD:1345394 6480464 Vincristine results in increased expression of LTA mRNA CTD PMID:23649840 zinc dichloride decreases expression ISO RGD:1345394 6480464 zinc chloride results in decreased expression of LTA mRNA CTD PMID:19428942 zinc dichloride increases expression ISO RGD:1345394 6480464 zinc chloride results in increased expression of LTA mRNA CTD PMID:21540303 zinc pyrithione increases expression ISO RGD:1345394 6480464 pyrithione zinc results in increased expression of LTA mRNA CTD PMID:21424779
Gene-Chemical Interaction Annotations
