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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jund
Name: JunD proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Jundaffects activityISOJund (Mus musculus)6480464CTDdeoxynivalenol affects the activity of JUND proteinPMID:10662601
Jundaffects localizationISOJund (Mus musculus)6480464CTDdeoxynivalenol affects the localization of JUND proteinPMID:12604842
Jundincreases activityISOJund (Mus musculus)6480464CTDdeoxynivalenol results in increased activity of JUND proteinPMID:15772366
Jundincreases expressionISOJUND (Homo sapiens)6480464CTDdeoxynivalenol results in increased expression of JUND mRNA; deoxynivalenol results in increased expression of JUND proteinPMID:22846391 PMID:33309878 PMID:33890134
Jundmultiple interactionsISOJUND (Homo sapiens)6480464CTD[Cadmium Chloride co-treated with deoxynivalenol] results in increased expression of JUND mRNAPMID:33309878
Jundmultiple interactionsISOJund (Mus musculus)6480464CTD4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [deoxynivalenol results in increased activity of JUND protein]PMID:15772366
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