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Gene: Hspa1l (heat shock protein family A (Hsp70) member 1 like) Rattus norvegicus
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Symbol: Hspa1l
Name: heat shock protein family A (Hsp70) member 1 like
Description: Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Predicted to be involved in several processes, including binding activity of sperm to zona pellucida; chaperone cofactor-dependent protein refolding; and protein refolding. Localizes to mitochondrial matrix. Predicted to colocalize with COP9 signalosome. Human ortholog(s) of this gene implicated in Kawasaki disease; major depressive disorder; schizophrenia; systemic lupus erythematosus; and uveitis. Orthologous to human HSPA1L (heat shock protein family A (Hsp70) member 1 like); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-schisandrin B; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1L; heat shock 70 kDa protein 3; heat shock 70kD protein 1-like; heat shock 70kD protein 1-like (mapped); heat shock protein 1-like; heat shock protein 70; Heat shock protein 70-1l; Hsp70-3; HSP70.3; Hspa1l_mapped; MGC112562; MGC114222
Orthologs:
Homo sapiens (human) : HSPA1L (heat shock protein family A (Hsp70) member 1 like)  HGNC  Alliance
Mus musculus (house mouse) : Hspa1l (heat shock protein 1-like)  MGI  Alliance
Canis lupus familiaris (dog) : LOC474850 (heat shock 70 kDa protein 1-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspa1l (heat shock protein family A (Hsp70) member 1 like)
Sus scrofa (pig) : HSPA1L (heat shock protein family A (Hsp70) member 1 like)
Chlorocebus sabaeus (African green monkey) : HSPA1L (heat shock protein family A (Hsp70) member 1 like)
Heterocephalus glaber (naked mole-rat) : Hspa1l (heat shock protein family A (Hsp70) member 1 like)
more info ...
Is Marker For: Strains:   SHR-Hspa1em1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0204,879,998 - 4,965,191 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,959,294 - 4,964,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,032,557 - 7,038,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera204,171,282 - 4,177,670 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Hspa1l
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1595925
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.