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Gene: Hspa1l (heat shock protein family A (Hsp70) member 1 like) Rattus norvegicus
Symbol: Hspa1l
Name: heat shock protein family A (Hsp70) member 1 like
Description: Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Predicted to be involved in several processes, including binding activity of sperm to zona pellucida; chaperone cofactor-dependent protein refolding; and protein refolding. Localizes to mitochondrial matrix. Predicted to colocalize with COP9 signalosome. Human ortholog(s) of this gene implicated in Kawasaki disease; major depressive disorder; schizophrenia; systemic lupus erythematosus; and uveitis. Orthologous to human HSPA1L (heat shock protein family A (Hsp70) member 1 like); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-schisandrin B; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1L; heat shock 70 kDa protein 3; heat shock 70kD protein 1-like; heat shock 70kD protein 1-like (mapped); heat shock protein 1-like; heat shock protein 70; Heat shock protein 70-1l; Hsp70-3; HSP70.3; Hspa1l_mapped; MGC112562; MGC114222
Homo sapiens (human) : HSPA1L (heat shock protein family A (Hsp70) member 1 like)  HGNC  Alliance
Mus musculus (house mouse) : Hspa1l (heat shock protein 1-like)  MGI  Alliance
Canis lupus familiaris (dog) : LOC474850 (heat shock 70 kDa protein 1-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspa1l (heat shock protein family A (Hsp70) member 1 like)
Sus scrofa (pig) : HSPA1L (heat shock protein family A (Hsp70) member 1 like)
Chlorocebus sabaeus (African green monkey) : HSPA1L (heat shock protein family A (Hsp70) member 1 like)
Heterocephalus glaber (naked mole-rat) : Hspa1l (heat shock protein family A (Hsp70) member 1 like)
more info ...
Is Marker For: Strains:   SHR-Hspa1em1Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0204,879,998 - 4,965,191 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,959,294 - 4,964,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,032,557 - 7,038,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera204,171,282 - 4,177,670 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Hspa1l
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1595925
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.