Hspa1l (heat shock protein family A (Hsp70) member 1 like) - Rat Genome Database

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Gene: Hspa1l (heat shock protein family A (Hsp70) member 1 like) Rattus norvegicus
Symbol: Hspa1l
Name: heat shock protein family A (Hsp70) member 1 like
RGD ID: 1595925
Description: Predicted to enable several functions, including ATP hydrolysis activity; ubiquitin protein ligase binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding; positive regulation of protein targeting to mitochondrion; and protein refolding. Predicted to act upstream of or within binding activity of sperm to zona pellucida. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in Kawasaki disease; major depressive disorder; schizophrenia; systemic lupus erythematosus; and uveitis. Orthologous to human HSPA1L (heat shock protein family A (Hsp70) member 1 like); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1L; heat shock 70 kDa protein 3; heat shock 70kD protein 1-like; heat shock 70kD protein 1-like (mapped); heat shock protein 1-like; heat shock protein 70; Heat shock protein 70-1l; Hsp70-3; HSP70.3; Hspa1l_mapped; MGC112562; MGC114222
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: Strains:   SHR-Hspa1em1Mcwi  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2203,848,843 - 3,855,571 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,848,843 - 3,855,571 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,548,331 - 4,555,029 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0203,910,388 - 3,917,087 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0204,448,330 - 4,454,924 (-)NCBIRnor_WKY
Rnor_6.0204,879,998 - 4,965,191 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,959,294 - 4,964,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,032,557 - 7,038,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera204,171,282 - 4,177,670 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
amphibole asbestos  (ISO)
antirheumatic drug  (ISO)
apigenin  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
Aurin  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bromoacetate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
CGP 52608  (ISO)
choline  (EXP)
clofibrate  (ISO)
cobalt atom  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
crocin-1  (EXP)
crotonaldehyde  (ISO)
D-penicillamine  (ISO)
decabromodiphenyl ether  (EXP)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (EXP)
ferric ammonium citrate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
gemcitabine  (ISO)
gentamycin  (EXP)
hemin  (ISO)
indometacin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoprenaline  (EXP,ISO)
ivermectin  (ISO)
L-methionine  (EXP)
L-serine  (ISO)
Licochalcone B  (ISO)
linalool  (EXP)
lithium atom  (EXP)
lithium hydride  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
monocrotaline  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nitroprusside  (ISO)
omeprazole  (EXP)
organoselenium compound  (ISO)
oxidopamine  (EXP)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
phenytoin  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
quercitrin  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
styrene  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
teriflunomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thimerosal  (ISO)
thiostrepton  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc pyrithione  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component


References - curated
# Reference Title Reference Citation
1. Heat shock protein 70 gene polymorphisms in sudden sensorineural hearing loss. Chien CY, etal., Audiol Neurootol. 2012;17(6):381-5. doi: 10.1159/000341815. Epub 2012 Aug 22.
2. Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus. Furnrohr BG, etal., Ann Rheum Dis. 2010 Nov;69(11):1983-9. Epub 2010 May 24.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia. Kim JJ, etal., Eur Arch Psychiatry Clin Neurosci. 2008 Jun;258(4):239-44.
5. HLA class III genes involvement in Kawasaki disease: a case-control study in Caucasian population. Maggioli E, etal., Int J Immunogenet. 2014 Feb;41(1):44-53. doi: 10.1111/iji.12077. Epub 2013 Jul 22.
6. Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Martin AM, etal., Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4180-5. Epub 2004 Mar 15.
7. Heat-shock protein-70 genes and response to antidepressants in major depression. Pae CU, etal., Prog Neuropsychopharmacol Biol Psychiatry. 2007 Jun 30;31(5):1006-11. Epub 2007 Feb 27.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. Rardin MJ, etal., J Biol Chem. 2008 May 30;283(22):15440-50. doi: 10.1074/jbc.M709547200. Epub 2008 Apr 2.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. Association between heat shock protein 70/Hom genetic polymorphisms and uveitis in patients with sarcoidosis. Spagnolo P, etal., Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3019-25.
15. MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Wiley SE, etal., Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5318-23. Epub 2007 Mar 21.
16. Association of hsp70 polymorphisms with risk of noise-induced hearing loss in Chinese automobile workers. Yang M, etal., Cell Stress Chaperones. 2006 Autumn;11(3):233-9.
Additional References at PubMed
PMID:7927536   PMID:12477932   PMID:15060004   PMID:15489334   PMID:17182002   PMID:18850735   PMID:21231916   PMID:21880732   PMID:22516433   PMID:24270810   PMID:26316108   PMID:28259758  
PMID:29476059   PMID:31904090  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2203,848,843 - 3,855,571 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,848,843 - 3,855,571 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,548,331 - 4,555,029 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0203,910,388 - 3,917,087 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0204,448,330 - 4,454,924 (-)NCBIRnor_WKY
Rnor_6.0204,879,998 - 4,965,191 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,959,294 - 4,964,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,032,557 - 7,038,454 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera204,171,282 - 4,177,670 (+)NCBICelera
Cytogenetic Map20p12NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38631,809,619 - 31,815,283 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl631,809,619 - 31,815,283 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,777,396 - 31,783,060 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,885,375 - 31,890,814 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,885,374 - 31,890,786NCBI
Celera633,375,646 - 33,381,084 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,563,804 - 31,569,242 (-)NCBIHuRef
CHM1_1631,779,530 - 31,784,969 (-)NCBICHM1_1
T2T-CHM13v2.0631,662,676 - 31,668,340 (-)NCBIT2T-CHM13v2.0
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391735,191,679 - 35,198,204 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,191,679 - 35,198,261 (+)EnsemblGRCm39 Ensembl
GRCm381734,972,703 - 34,979,228 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,972,703 - 34,979,285 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,109,648 - 35,116,173 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,580,788 - 34,587,281 (+)NCBIMGSCv36mm8
Celera1738,068,927 - 38,075,454 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.51NCBI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan1642,248,104 - 42,260,544 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,470,745 - 31,483,615 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,357,626 - 32,370,055 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,358,054 - 32,359,979 (-)Ensemblpanpan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1121,281,164 - 1,285,010 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,281,472 - 1,285,440 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,416,835 - 1,420,649 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,424,019 - 1,427,833 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,423,961 - 1,428,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,283,032 - 1,286,847 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,350,176 - 1,353,991 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,414,602 - 1,418,416 (-)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440494635,816,113 - 35,825,083 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,736,243 - 1,745,231 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049367271,735,880 - 1,745,231 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl723,909,960 - 23,914,629 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,909,960 - 23,938,678 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.11740,206,365 - 40,211,996 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,209,754 - 40,211,676 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,724,065 - 31,729,529 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_00462475424,416,738 - 24,424,613 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,403,438 - 24,423,477 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Hspa1l
71 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:190
Count of miRNA genes:150
Interacting mature miRNAs:160
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
737973Pia21Pristane induced arthritis QTL 214.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2036216564606812Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat

Markers in Region
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map20p12UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,871,310 - 3,871,800 (-)MAPPERmRatBN7.2
mRatBN7.2203,856,718 - 3,857,207 (-)MAPPERmRatBN7.2
Rnor_6.0204,878,745 - 4,879,233NCBIRnor6.0
Rnor_6.0202,700,781 - 2,701,269NCBIRnor6.0
Rnor_5.0204,803,650 - 4,804,138UniSTSRnor5.0
Rnor_5.0206,959,145 - 6,959,633UniSTSRnor5.0
RGSC_v3.4203,956,153 - 3,956,641UniSTSRGSC3.4
Celera204,155,481 - 4,155,969UniSTS
Celera204,169,646 - 4,170,134UniSTS
Cytogenetic Map20p12UniSTS

Related Rat Strains
The following Strains have been annotated to Hspa1l


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 1
Medium 1 6
Low 35 6 8 10 15 4 10 10 8
Below cutoff 3 8 28 18 17 18 59 30 24 1


Reference Sequences
RefSeq Acc Id: ENSRNOT00000074223   ⟹   ENSRNOP00000063974
RefSeq Status:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,848,843 - 3,855,571 (-)Ensembl
Rnor_6.0 Ensembl204,959,294 - 4,964,963 (+)Ensembl
RefSeq Acc Id: NM_212546   ⟹   NP_997711
RefSeq Status: VALIDATED
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,848,843 - 3,855,571 (-)NCBI
Rnor_6.0204,959,294 - 4,965,191 (+)NCBI
Rnor_5.0207,032,557 - 7,038,454 (+)NCBI
Celera204,171,282 - 4,177,670 (+)RGD
Protein Sequences
Protein RefSeqs NP_997711 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI08295 (Get FASTA)   NCBI Sequence Viewer  
  AAI08298 (Get FASTA)   NCBI Sequence Viewer  
  CAE83979 (Get FASTA)   NCBI Sequence Viewer  
  EDL83474 (Get FASTA)   NCBI Sequence Viewer  
  P55063 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_997711   ⟸   NM_212546
- UniProtKB: Q6MG67 (UniProtKB/Swiss-Prot),   P55063 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063974   ⟸   ENSRNOT00000074223

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P55063-F1-model_v2 AlphaFold P55063 1-641 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701377
Promoter ID:EPDNEW_R11901
Type:multiple initiation site
Description:heat shock protein family A member 1 like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Rat AssemblyChrPosition (strand)Source
Rnor_6.0204,959,295 - 4,959,355EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595925 AgrOrtholog
BioCyc Gene G2FUF-4622 BioCyc
Ensembl Genes ENSRNOG00000047966 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000063974 ENTREZGENE
  ENSRNOP00000063974.1 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074223 ENTREZGENE
  ENSRNOT00000074223.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1270.10 UniProtKB/Swiss-Prot UniProtKB/Swiss-Prot
  3.30.420.40 UniProtKB/Swiss-Prot
InterPro ATPase_NBD UniProtKB/Swiss-Prot
  Heat_shock_70_CS UniProtKB/Swiss-Prot
  HSP70_C_sf UniProtKB/Swiss-Prot
  HSP70_peptide-bd_sf UniProtKB/Swiss-Prot
  Hsp_70_fam UniProtKB/Swiss-Prot
KEGG Report rno:24963 UniProtKB/Swiss-Prot
  PTHR19375 UniProtKB/Swiss-Prot
Pfam HSP70 UniProtKB/Swiss-Prot
PhenoGen Hspa1l PhenoGen
PROSITE HSP70_1 UniProtKB/Swiss-Prot
  HSP70_2 UniProtKB/Swiss-Prot
  HSP70_3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF100920 UniProtKB/Swiss-Prot
  SSF100934 UniProtKB/Swiss-Prot
  SSF53067 UniProtKB/Swiss-Prot
UniProt HS71L_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q32P36 UniProtKB/Swiss-Prot
  Q6MG67 UniProtKB/Swiss-Prot

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-25 Hspa1l  heat shock protein family A (Hsp70) member 1 like  Hspa1l  heat shock protein 1-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Hspa1l  heat shock protein 1-like  Hspa1l  heat shock 70kD protein 1-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   heat shock 70kD protein 1-like  Hspa1l  heat shock 70kD protein 1-like (mapped)  Name updated 737654 APPROVED
2007-04-11 Hspa1l  heat shock 70kD protein 1-like (mapped)  Hspa1l_mapped  heat shock 70kD protein 1-like (mapped)  Data Merged 737654 APPROVED
2006-11-20 Hspa1l  heat shock 70kD protein 1-like (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Hspa1l_mapped  heat shock 70kD protein 1-like (mapped)      Symbol and Name updated 1556543 APPROVED
2002-11-06 Hspa1l  heat shock 70kD protein 1-like    Heat shock protein 70-1l  Name updated 625702 APPROVED
2002-06-10 Hspa1l  Heat shock protein 70-1l      Symbol and Name status set to approved 70586 APPROVED