Wdr5 (WD repeat domain 5) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Wdr5 (WD repeat domain 5) Rattus norvegicus
Analyze
Symbol: Wdr5
Name: WD repeat domain 5
RGD ID: 1305159
Description: Predicted to enable methylated histone binding activity. Predicted to contribute to histone H3K4 methyltransferase activity. Involved in neuron projection development. Located in nucleus. Orthologous to human WDR5 (WD repeat domain 5); PARTICIPATES IN histone modification pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100912075; LOC108348033; LOC362093; MGC114572; WD repeat-containing protein 5; WD repeat-containing protein 5-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2310,836,964 - 10,856,682 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl310,837,025 - 10,856,671 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx313,905,180 - 13,924,115 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0322,490,606 - 22,509,541 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0320,745,229 - 20,764,191 (+)NCBIRnor_WKY
Rnor_6.036,061,892 - 6,080,724 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl36,061,940 - 6,080,680 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0311,422,748 - 11,441,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.436,432,879 - 6,451,846 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.136,432,099 - 6,450,947 (+)NCBI
Celera35,632,259 - 5,651,225 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. Brown SA, etal., Science. 2005 Apr 29;308(5722):693-6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. X-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expression. Nakagawa T and Xiong Y, Mol Cell. 2011 Aug 5;43(3):381-91. doi: 10.1016/j.molcel.2011.05.033.
5. Readout of epigenetic modifications. Patel DJ and Wang Z, Annu Rev Biochem. 2013;82:81-118. doi: 10.1146/annurev-biochem-072711-165700.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Shilatifard A Annu Rev Biochem. 2012;81:65-95. doi: 10.1146/annurev-biochem-051710-134100.
8. ATAC-king the complexity of SAGA during evolution. Spedale G, etal., Genes Dev. 2012 Mar 15;26(6):527-41. doi: 10.1101/gad.184705.111.
9. The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles. Topalidou I, etal., PLoS Genet. 2016 May 18;12(5):e1006074. doi: 10.1371/journal.pgen.1006074. eCollection 2016 May.
Additional References at PubMed
PMID:11551928   PMID:12477932   PMID:15489334   PMID:15960975   PMID:16600877   PMID:17355966   PMID:17500065   PMID:17998332   PMID:18838386   PMID:18838538   PMID:18840606   PMID:19103755  
PMID:19556245   PMID:20018852   PMID:20508642   PMID:22514746   PMID:24051374   PMID:26324722  


Genomics

Comparative Map Data
Wdr5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2310,836,964 - 10,856,682 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl310,837,025 - 10,856,671 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx313,905,180 - 13,924,115 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0322,490,606 - 22,509,541 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0320,745,229 - 20,764,191 (+)NCBIRnor_WKY
Rnor_6.036,061,892 - 6,080,724 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl36,061,940 - 6,080,680 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0311,422,748 - 11,441,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.436,432,879 - 6,451,846 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.136,432,099 - 6,450,947 (+)NCBI
Celera35,632,259 - 5,651,225 (+)NCBICelera
Cytogenetic Map3p12NCBI
WDR5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389134,135,199 - 134,159,968 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl9134,135,365 - 134,159,968 (+)EnsemblGRCh38hg38GRCh38
GRCh379137,000,321 - 137,025,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369135,991,031 - 136,014,915 (+)NCBINCBI36Build 36hg18NCBI36
Build 349134,034,467 - 134,053,330NCBI
Celera9107,546,368 - 107,570,384 (+)NCBICelera
Cytogenetic Map9q34.2NCBI
HuRef9106,494,213 - 106,518,092 (+)NCBIHuRef
CHM1_19137,147,954 - 137,171,840 (+)NCBICHM1_1
T2T-CHM13v2.09146,348,934 - 146,373,713 (+)NCBIT2T-CHM13v2.0
Wdr5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39227,405,159 - 27,426,547 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl227,405,169 - 27,426,547 (+)EnsemblGRCm39 Ensembl
GRCm38227,515,147 - 27,536,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl227,515,157 - 27,536,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv37227,370,667 - 27,392,055 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36227,337,223 - 27,358,544 (+)NCBIMGSCv36mm8
Celera227,217,888 - 27,239,293 (+)NCBICelera
Cytogenetic Map2A3NCBI
Wdr5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555133,198,980 - 3,216,468 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555133,198,655 - 3,213,754 (+)NCBIChiLan1.0ChiLan1.0
WDR5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19133,848,185 - 133,872,889 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9133,848,185 - 133,872,889 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v09105,241,415 - 105,265,925 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
WDR5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1950,352,600 - 50,371,224 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl950,352,472 - 50,371,236 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha949,631,684 - 49,651,782 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0951,225,059 - 51,245,284 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl951,225,396 - 51,245,435 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1949,985,941 - 50,006,039 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0950,328,703 - 50,348,976 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0950,406,626 - 50,426,733 (+)NCBIUU_Cfam_GSD_1.0
Wdr5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947200,415,266 - 200,430,169 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366692,943,656 - 2,958,409 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366692,943,759 - 2,959,788 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1273,560,283 - 273,578,063 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11273,560,274 - 273,577,827 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21307,533,235 - 307,550,804 (+)NCBISscrofa10.2Sscrofa10.2susScr3
WDR5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1123,982,998 - 4,007,605 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl123,983,013 - 4,007,119 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660581,089,087 - 1,113,046 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247602,274,813 - 2,292,379 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247602,275,660 - 2,291,796 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wdr5
25 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:207
Count of miRNA genes:142
Interacting mature miRNAs:171
Transcripts:ENSRNOT00000011556
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat

Markers in Region
RH141408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2310,856,268 - 10,856,455 (+)MAPPERmRatBN7.2
Rnor_6.036,080,311 - 6,080,497NCBIRnor6.0
Rnor_5.0311,441,161 - 11,441,347UniSTSRnor5.0
RGSC_v3.436,451,451 - 6,451,637UniSTSRGSC3.4
Celera35,650,830 - 5,651,016UniSTS
RH 3.4 Map310.7UniSTS
Cytogenetic Map3p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 41 26 19 26 1 1 73 30 41 11 1
Low 11 16 15 15 7 10 1 5 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000011556   ⟹   ENSRNOP00000011556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl310,837,025 - 10,856,671 (+)Ensembl
Rnor_6.0 Ensembl36,061,940 - 6,080,680 (+)Ensembl
RefSeq Acc Id: NM_001039034   ⟹   NP_001034123
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2310,837,696 - 10,856,664 (+)NCBI
Rnor_6.036,062,593 - 6,080,706 (+)NCBI
Rnor_5.0311,422,748 - 11,441,574 (+)NCBI
RGSC_v3.436,432,879 - 6,451,846 (+)RGD
Celera35,632,259 - 5,651,225 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233831   ⟹   XP_006233893
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2310,836,964 - 10,856,682 (+)NCBI
Rnor_6.036,061,892 - 6,080,724 (+)NCBI
Rnor_5.0311,422,748 - 11,441,574 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001034123 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233893 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00157 (Get FASTA)   NCBI Sequence Viewer  
  EDL93432 (Get FASTA)   NCBI Sequence Viewer  
  Q498M4 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001034123   ⟸   NM_001039034
- UniProtKB: Q498M4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006233893   ⟸   XM_006233831
- Peptide Label: isoform X1
- UniProtKB: Q498M4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011556   ⟸   ENSRNOT00000011556

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q498M4-F1-model_v2 AlphaFold Q498M4 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691929
Promoter ID:EPDNEW_R2452
Type:initiation region
Name:Wdr5_1
Description:WD repeat domain 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.036,061,938 - 6,061,998EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305159 AgrOrtholog
BioCyc Gene G2FUF-50294 BioCyc
Ensembl Genes ENSRNOG00000008212 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000011556 ENTREZGENE
  ENSRNOP00000011556.4 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011556 ENTREZGENE
  ENSRNOT00000011556.6 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7462311 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362093 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114572 IMAGE-MGC_LOAD
NCBI Gene 362093 ENTREZGENE
Pfam WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Wdr5 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2Q668_RAT UniProtKB/TrEMBL
  Q498M4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Wdr5  WD repeat domain 5  LOC108348033  WD repeat-containing protein 5-like  Data Merged 737654 PROVISIONAL
2016-08-02 LOC108348033  WD repeat-containing protein 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2015-07-29 Wdr5  WD repeat domain 5  LOC100912075  WD repeat-containing protein 5-like  Data Merged 737654 PROVISIONAL
2012-07-05 LOC100912075  WD repeat-containing protein 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Wdr5  WD repeat domain 5  Wdr5_predicted  WD repeat domain 5 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Wdr5_predicted  WD repeat domain 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED