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Gene: Hdgf (heparin binding growth factor) Rattus norvegicus
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Symbol: Hdgf
Name: heparin binding growth factor
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and protein localization to nucleus. Localizes to the nucleus. Orthologous to several human genes including HDGF (heparin binding growth factor); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hepatoma-derived growth factor
Orthologs:
Homo sapiens (human) : HDGF (heparin binding growth factor)  HGNC  Alliance
Mus musculus (house mouse) : Hdgf (heparin binding growth factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdgf (heparin binding growth factor)
Pan paniscus (bonobo/pygmy chimpanzee) : HDGF (heparin binding growth factor)
Canis lupus familiaris (dog) : HDGF (heparin binding growth factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdgf (heparin binding growth factor)
Sus scrofa (pig) : HDGF (heparin binding growth factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02187,274,898 - 187,284,670 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02206,679,009 - 206,687,542 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42179,981,346 - 179,991,892 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12179,931,451 - 179,941,998 (+)NCBI
Celera2167,319,679 - 167,328,614 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hdgf
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70961
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.