Mt-co1 (mitochondrially encoded cytochrome c oxidase I) - Rat Genome Database

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Gene: Mt-co1 (mitochondrially encoded cytochrome c oxidase I) Rattus norvegicus
Analyze
Symbol: Mt-co1
Name: mitochondrially encoded cytochrome c oxidase I
RGD ID: 621871
Description: Predicted to enable heme binding activity and metal ion binding activity. Predicted to contribute to cytochrome-c oxidase activity. Involved in several processes, including aging; response to copper ion; and response to electrical stimulus. Located in mitochondrion. Used to study hepatocellular carcinoma. Biomarker of Parkinsonism. Orthologous to human MT-CO1 (mitochondrially encoded cytochrome c oxidase I); PARTICIPATES IN electron transport chain pathway; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Co1; COI; Cox1; cytochrome c oxidase 1 mitochondrial; cytochrome c oxidase I, mitochondrial; cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase 1; Mt-coi; mt_Co1
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2MT5,323 - 6,867 (+)NCBImRatBN7.2
mRatBN7.2 EnsemblMT5,323 - 6,867 (+)Ensembl
Rnor_6.0MT5,323 - 6,867 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblMT5,323 - 6,867 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0MT5,323 - 6,867 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4MT5,323 - 6,867 (+)NCBIRGSC3.4rn4RGSC3.4
Cytogenetic MapMT NCBI


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(R)-carnitine  (ISO)
(S)-nicotine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid  (ISO)
7,12-dimethyltetraphene  (EXP)
acetylsalicylic acid  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
Aflatoxin G1  (ISO)
Aflatoxin G2  (ISO)
aldehydo-D-glucose  (EXP)
Allylamine  (EXP)
alpha-D-galactose  (EXP)
alpha-hexachlorocyclohexane  (EXP)
aminoguanidine  (EXP)
aristolochic acid  (ISO)
atorvastatin calcium  (EXP)
atrazine  (EXP,ISO)
beauvericin  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (EXP)
carbon nanotube  (ISO)
chalcones  (ISO)
chloramphenicol  (ISO)
chlorogenic acid  (ISO)
clofibrate  (EXP)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP)
D-glucose  (EXP)
dehydroepiandrosterone  (EXP)
desferrioxamine B  (ISO)
dexamethasone  (EXP)
dioxygen  (EXP,ISO)
disodium selenite  (EXP)
disulfiram  (EXP)
doxorubicin  (EXP,ISO)
enniatin  (ISO)
ethidium  (ISO)
folic acid  (ISO)
galactose  (EXP)
genistein  (EXP,ISO)
gentamycin  (EXP)
glucose  (EXP)
herbicide  (ISO)
hydrogen peroxide  (EXP)
hydroquinone  (ISO)
hydroxytyrosol  (EXP)
ivermectin  (ISO)
kojic acid  (ISO)
lamivudine  (ISO)
lead nitrate  (EXP)
lenvatinib  (EXP)
Licochalcone B  (ISO)
LY294002  (EXP)
malathion  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
N-acetyl-L-cysteine  (EXP)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
nicotinamide  (ISO)
nicotine  (EXP)
nitric oxide  (EXP)
O-acetyl-L-carnitine  (EXP)
ochratoxin A  (ISO)
Osajin  (ISO)
perfluorooctanoic acid  (EXP)
PhIP  (EXP)
picloram  (ISO)
pirinixic acid  (EXP)
Pomiferin  (ISO)
puerarin  (EXP,ISO)
pyrroloquinoline quinone  (ISO)
pyruvic acid  (EXP)
quercetin  (EXP)
resveratrol  (ISO)
Rosavin  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP)
sodium hydrogensulfite  (EXP)
sulforaphane  (ISO)
sulfur dioxide  (EXP)
sunitinib  (ISO)
T-2 toxin  (EXP)
tetraphene  (ISO)
thapsigargin  (ISO)
tofacitinib  (ISO)
trichlopyr  (ISO)
trilobatin  (EXP)
tunicamycin  (ISO)
uridine  (ISO)
valproic acid  (EXP,ISO)
zalcitabine  (ISO)
zearalenone  (ISO)
zidovudine  (EXP,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12506326   PMID:17429720   PMID:18198996   PMID:18456673   PMID:19087623   PMID:24058566   PMID:25107896   PMID:26316108   PMID:35326380  


Genomics

Comparative Map Data
Mt-co1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2MT5,323 - 6,867 (+)NCBImRatBN7.2
mRatBN7.2 EnsemblMT5,323 - 6,867 (+)Ensembl
Rnor_6.0MT5,323 - 6,867 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblMT5,323 - 6,867 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0MT5,323 - 6,867 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4MT5,323 - 6,867 (+)NCBIRGSC3.4rn4RGSC3.4
Cytogenetic MapMT NCBI
MT-CO1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38MT5,904 - 7,445 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblMT5,904 - 7,445 (+)EnsemblGRCh38hg38GRCh38
GRCh37MT5,904 - 7,445 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36MT5,905 - 7,446 (+)NCBINCBI36hg18NCBI36
mt-Co1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39MT5,328 - 6,872 (+)NCBIGRCm39mm39
GRCm39 EnsemblMT5,328 - 6,872 (+)Ensembl
GRCm38MT5,328 - 6,872 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblMT5,328 - 6,872 (+)EnsemblGRCm38mm10GRCm38
MGSCv37MT5,328 - 6,872 (+)NCBIGRCm37mm9NCBIm37
MT-CO1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1MT5,349 - 6,893 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblMT5,349 - 6,893 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaMT5,349 - 6,893 (+)NCBI
MT-CO1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblMT6,511 - 8,055 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1MT6,511 - 8,055 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2MT6,511 - 8,055 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:9
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000050156
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 3 43 57 41 19 41 8 11 74 35 41 11 8
Medium
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000050156   ⟹   ENSRNOP00000039048
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblMT5,323 - 6,867 (+)Ensembl
Rnor_6.0 EnsemblMT5,323 - 6,867 (+)Ensembl
Reference Sequences
RefSeq Acc Id: ENSRNOP00000039048   ⟸   ENSRNOT00000050156
Protein Domains
COX1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P05503-F1-model_v2 AlphaFold P05503 1-514 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621871 AgrOrtholog
BioCyc Gene G2FUF-22 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
Ensembl Genes ENSRNOG00000034234 Ensembl, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000039048 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000050156 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.210.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyt_c_oxase-like_su1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_c_oxase-like_su1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_C_Oxase_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_c_Oxase_su1_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_c_oxase_su1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:26195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 26195 ENTREZGENE
PANTHER PTHR10422 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam COX1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mt-co1 PhenoGen
PRINTS CYCOXIDASEI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE COX1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COX1_CUB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81442 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt COX1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q8HIC9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-04 Mt-co1  mitochondrially encoded cytochrome c oxidase I  Mt-co1  mitochondrially encoded cytochrome c oxidase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-12-02 Mt-co1  mitochondrially encoded cytochrome c oxidase 1  Mt-co1  mitochondrially encoded cytochrome c oxidase I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-09-05 Mt-co1  mitochondrially encoded cytochrome c oxidase I  Mt-coi  mitochondrially encoded cytochrome c oxidase I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-02-27 Mt-coi  mitochondrially encoded cytochrome c oxidase I  Mt-co1  mitochondrially encoded cytochrome c oxidase I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Mt-co1  mitochondrially encoded cytochrome c oxidase I  mt-Co1  cytochrome c oxidase I, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 Krt1-9  cytochrome c oxidase I, mitochondrial  mt-Co1  cytochrome c oxidase subunit 1  Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-08-07 mt-Co1  cytochrome c oxidase subunit 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein one of the three mitochondrial coded subunits, among the 13 subunits of each COX monomer 724423