Gene: Mbtps1 (membrane-bound transcription factor peptidase, site 1) Rattus norvegicus
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Symbol: Mbtps1
Name: membrane-bound transcription factor peptidase, site 1
Description: ENCODES a protein that exhibits serine-type endopeptidase activity; endopeptidase activity (ortholog); INVOLVED IN lipid metabolic process (ortholog); lysosome organization (ortholog); protein import into nucleus (ortholog); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Craniofacial Abnormalities (ortholog); hepatocellular carcinoma (ortholog); Prostatic Neoplasms (ortholog); FOUND IN Golgi apparatus; Golgi stack (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; dibutyl phthalate
AGR Description: Exhibits serine-type endopeptidase activity; predicted to be involved in several processes, including lipid metabolic process, lysosome organization, and protein import into nucleus; localizes to the Golgi apparatus; orthologous to human MBTPS1 (membrane bound transcription factor peptidase, site 1).
Merged Description: Exhibits serine-type endopeptidase activity; predicted to be involved in several processes, including lipid metabolic process, lysosome organization, and protein import into nucleus; localizes to the Golgi apparatus; orthologous to human MBTPS1 (membrane bound transcription factor peptidase, site 1); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH ammonium chloride; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endopeptidase S1P; membrane-bound transcription factor protease, site 1; membrane-bound transcription factor site-1 protease; S1p; S1P endopeptidase; site-1 protease; Ski-1; subtilisin/kexin isozyme 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01952,146,507 - 52,206,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01962,894,989 - 62,954,792 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41949,751,424 - 49,802,700 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11949,756,304 - 49,807,581 (-)NCBI
Celera1946,820,963 - 46,871,847 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mbtps1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70935
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.