Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Bcl10 (BCL10, immune signaling adaptor) Rattus norvegicus
Analyze
Symbol: Bcl10
Name: BCL10, immune signaling adaptor
Description: Predicted to contribute to kinase activator activity. Involved in positive regulation of apoptotic process and protein heterooligomerization. Localizes to the cytosol and protein-containing complex. Human ortholog(s) of this gene implicated in MALT lymphoma; malignant mesothelioma; non-Hodgkin lymphoma; and primary immunodeficiency disease. Orthologous to human BCL10 (BCL10 immune signaling adaptor); PARTICIPATES IN nuclear factor kappa B signaling pathway; B cell receptor signaling pathway; T cell receptor signaling pathway; INTERACTS WITH (+)-pilocarpine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10; B-cell lymphoma/leukemia 10; bcl-10; R-RCD1; RCD
Orthologs:
Homo sapiens (human) : BCL10 (BCL10 immune signaling adaptor)  HGNC  Alliance
Mus musculus (house mouse) : Bcl10 (B cell leukemia/lymphoma 10)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bcl10 (BCL10 immune signaling adaptor)
Pan paniscus (bonobo/pygmy chimpanzee) : BCL10 (BCL10 immune signaling adaptor)
Canis lupus familiaris (dog) : BCL10 (BCL10 immune signaling adaptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcl10 (BCL10 immune signaling adaptor)
Sus scrofa (pig) : BCL10 (BCL10 immune signaling adaptor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02251,805,392 - 251,814,957 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02270,330,540 - 270,340,105 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42244,116,880 - 244,126,393 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12244,103,619 - 244,113,130 (+)NCBI
Celera2226,822,923 - 226,832,565 (+)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Bcl10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620544
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.