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Gene: Man1b1 (mannosidase, alpha, class 1B, member 1) Rattus norvegicus
Symbol: Man1b1
Name: mannosidase, alpha, class 1B, member 1
Description: Predicted to have mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing; mannose trimming involved in glycoprotein ERAD pathway; and trimming of terminal mannose on B branch. Predicted to localize to endoplasmic reticulum quality control compartment and membrane. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human MAN1B1 (mannosidase alpha class 1B member 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH bisphenol A; C60 fullerene; glafenine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; ER alpha-1,2-mannosidase; ER mannosidase 1; ERMan1; LOC499751; mannosidase alpha class 1B member 1; RGD1563595; similar to Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (ER alpha-1,2-mannosidase); similar to Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific processing alpha-mannosidase) (UNQ747/PRO1477)
Homo sapiens (human) : MAN1B1 (mannosidase alpha class 1B member 1)  HGNC  Alliance
Mus musculus (house mouse) : Man1b1 (mannosidase, alpha, class 1B, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Man1b1 (mannosidase alpha class 1B member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MAN1B1 (mannosidase alpha class 1B member 1)
Canis lupus familiaris (dog) : LOC480667 (endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Man1b1 (mannosidase alpha class 1B member 1)
Sus scrofa (pig) : LOC110258087 (endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase-like)
Chlorocebus sabaeus (African green monkey) : MAN1B1 (mannosidase alpha class 1B member 1)
Heterocephalus glaber (naked mole-rat) : Man1b1 (mannosidase alpha class 1B member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.032,547,259 - 2,569,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,547,986 - 2,569,049 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.032,528,747 - 2,550,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,493,476 - 3,514,884 (+)NCBIRGSC3.4rn4RGSC3.4
Celera32,970,480 - 2,991,187 (+)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Man1b1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563595
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.