Gene: Man1b1 (mannosidase, alpha, class 1B, member 1) Rattus norvegicus
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Symbol: Man1b1
Name: mannosidase, alpha, class 1B, member 1
Description: ENCODES a protein that exhibits mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (ortholog); INVOLVED IN endoplasmic reticulum mannose trimming (ortholog); mannose trimming involved in glycoprotein ERAD pathway (ortholog); protein alpha-1,2-demannosylation (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Mental Retardation, Autosomal Recessive 15 (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum quality control compartment (ortholog); membrane (ortholog); INTERACTS WITH bisphenol A; C60 fullerene; glafenine
AGR Description: Predicted to have mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; predicted to be involved in N-glycan processing, mannose trimming involved in glycoprotein ERAD pathway, and trimming of terminal mannose on B branch; predicted to localize to the endoplasmic reticulum quality control compartment and membrane; orthologous to human MAN1B1 (mannosidase alpha class 1B member 1).
Merged Description: Predicted to have mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; predicted to be involved in N-glycan processing, mannose trimming involved in glycoprotein ERAD pathway, and trimming of terminal mannose on B branch; predicted to localize to the endoplasmic reticulum quality control compartment and membrane; orthologous to human MAN1B1 (mannosidase alpha class 1B member 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH bisphenol A; C60 fullerene; glafenine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; ER alpha-1,2-mannosidase; ER mannosidase 1; ERMan1; LOC499751; mannosidase alpha class 1B member 1; RGD1563595; similar to Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (ER alpha-1,2-mannosidase); similar to Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific processing alpha-mannosidase) (UNQ747/PRO1477)
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.032,547,259 - 2,569,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.032,528,747 - 2,550,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,493,476 - 3,514,884 (+)NCBIRGSC3.4rn4RGSC3.4
Celera32,970,480 - 2,991,187 (+)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
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RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Man1b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563595
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.