Gene: Cacna1d (calcium voltage-gated channel subunit alpha1 D) Rattus norvegicus
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Symbol: Cacna1d
Name: calcium voltage-gated channel subunit alpha1 D
Description: ENCODES a protein that exhibits ankyrin binding; high voltage-gated calcium channel activity; PDZ domain binding; INVOLVED IN aging; calcium ion import; calcium ion transport; PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer's disease pathway; ASSOCIATED WITH Drug-Induced Dyskinesia; Memory Disorders; sciatic neuropathy; FOUND IN apical plasma membrane; cell surface; cytoplasm; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol
AGR Description: Exhibits PDZ domain binding activity, ankyrin binding activity, and high voltage-gated calcium channel activity; involved in several processes, including aging, calcium ion import, and positive regulation of transport; localizes to several cellular components, including the apical plasma membrane, cell surface, and neuron projection; biomarker of sciatic neuropathy; orthologous to human CACNA1D (calcium voltage-gated channel subunit alpha1 D).
Merged Description: Exhibits PDZ domain binding activity, ankyrin binding activity, and high voltage-gated calcium channel activity; involved in several processes, including aging, calcium ion import, and positive regulation of transport; localizes to several cellular components, including the apical plasma membrane, cell surface, and neuron projection; biomarker of sciatic neuropathy; orthologous to human CACNA1D (calcium voltage-gated channel subunit alpha1 D); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer's disease pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: brain class D; calcium channel alpha-1 subunit; calcium channel, L type, alpha-1 polypeptide, isoform 2; calcium channel, voltage-dependent, L type, alpha 1D subunit; CaV1.3alpha1; RBD; voltage-dependent calcium channel subunit alpha1D; voltage-dependent L-type calcium channel subunit alpha-1D; voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker; voltage-gated calcium channel subunit alpha Cav1.3
Orthologs:
Homo sapiens (human) : CACNA1D (calcium voltage-gated channel subunit alpha1 D)  HGNC  Alliance
Mus musculus (house mouse) : Cacna1d (calcium channel, voltage-dependent, L type, alpha 1D subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cacna1d (calcium voltage-gated channel subunit alpha1 D)
Pan paniscus (bonobo/pygmy chimpanzee) : CACNA1D (calcium voltage-gated channel subunit alpha1 D)
Canis lupus familiaris (dog) : CACNA1D (calcium voltage-gated channel subunit alpha1 D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cacna1d (calcium voltage-gated channel subunit alpha1 D)
Sus scrofa (pig) : CACNA1D (calcium voltage-gated channel subunit alpha1 D)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0166,110,294 - 6,405,022 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0166,044,524 - 6,339,170 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4165,383,259 - 5,703,361 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1165,383,256 - 5,703,359NCBI
Celera169,667,490 - 9,955,564 (+)NCBICelera
Cytogenetic Map16p16NCBI
RH 3.4 Map161.3RGD
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

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Strain Sequence Variants (Rnor 5.0)
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Nomenclature History
RGD Curation Notes
  
More on Cacna1d
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70973
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.