Gsto2 (glutathione S-transferase omega 2)

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Gene: Gsto2 (glutathione S-transferase omega 2) Rattus norvegicus

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Symbol:

Gsto2

Name:

glutathione S-transferase omega 2

RGD ID:

1310764

Description:

Predicted to enable glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; and identical protein binding activity. Predicted to be involved in several processes, including L-ascorbic acid metabolic process; cellular response to arsenic-containing substance; and glutathione metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Orthologous to human GSTO2 (glutathione S-transferase omega 2); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; glutathione synthase deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; atrazine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

glutathione S-transferase omega 2-2; glutathione S-transferase omega-2; glutathione-dependent dehydroascorbate reductase; GSTO 2-2; GSTO-2; LOC103690044; LOC309465; MMA(V) reductase; monomethylarsonic acid reductase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GSTO2 (glutathione S-transferase omega 2)	RGD	RGD
Mus musculus (house mouse):	Gsto2 (glutathione S-transferase omega 2)	RGD	RGD
Pan paniscus (bonobo/pygmy chimpanzee):	GSTO2 (glutathione S-transferase omega 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GSTO2 (glutathione S-transferase omega 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gsto2 (glutathione S-transferase omega 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GSTO2 (glutathione S-transferase omega 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GSTO2 (glutathione S-transferase omega 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GSTO2 (glutathione S-transferase omega 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gsto2 (glutathione S-transferase omega 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gsto2 (glutathione S-transferase omega 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C02D5.4	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	GstO2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	GstO3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gst-44	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gsto-1	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gsto-2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	GstO1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	se	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gsto1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gsto2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	LOC100498493	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	256,673,376 - 256,695,154 (+)	NCBI		GRCr8
mRatBN7.2	1	246,731,314 - 246,757,592 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	246,732,089 - 246,753,866 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	254,859,384 - 254,881,207 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	261,552,355 - 261,574,175 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	254,202,420 - 254,224,048 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	267,617,517 - 267,640,455 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	267,607,416 - 267,640,455 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	1	271,229,036 - 271,243,517 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	275,050,163 - 275,072,303 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	1	278,656,945 - 278,671,426 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	253,239,392 - 253,275,110 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	253,504,135 - 253,539,851 (+)	NCBI
Celera	1	242,496,974 - 242,517,641 (+)	NCBI		Celera
Cytogenetic Map	1	q54	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

asthma (ISO)

desmoplastic/nodular medulloblastoma (ISO)

Parkinson's disease (ISO)

urinary bladder cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4-nitrophenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP)

amiodarone (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

carbamazepine (ISO)

carbon nanotube (ISO)

chlorpyrifos (EXP)

cisplatin (ISO)

copper(II) sulfate (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

diazinon (EXP)

Dibutyl phosphate (ISO)

dieldrin (EXP)

dimethylarsinic acid (ISO)

endosulfan (EXP)

entinostat (ISO)

flutriafol (ISO)

gentamycin (EXP)

indole-3-methanol (EXP)

ketamine (EXP)

microcystin (EXP)

N-acetyl-L-cysteine (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

naphthalene (ISO)

nickel atom (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

propanal (ISO)

quercetin (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

sodium fluoride (ISO)

Soman (EXP)

T-2 toxin (EXP)

tamoxifen (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene 2,4-diisocyanate (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular oxidant detoxification (IEA)

cellular response to arsenic-containing substance (IEA,ISO,ISS)

glutathione metabolic process (IBA,IEA)

L-ascorbic acid metabolic process (IBA,IEA,ISO,ISS)

xenobiotic metabolic process (IEA,ISO,ISS)

Cellular Component

cytoplasm (IBA,IEA)

Molecular Function

glutathione dehydrogenase (ascorbate) activity (IBA,IEA,ISO,ISS)

glutathione transferase activity (IBA,IEA)

identical protein binding (IEA,ISO)

methylarsonate reductase activity (IEA)

oxidoreductase activity (ISO,ISS)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

glutathione conjugation pathway (ISO)

glutathione metabolic pathway (IEA,ISO)

glutathione synthase deficiency pathway (ISO)

glutathionuria disease pathway (ISO)

phase I biotransformation pathway via cytochrome P450 (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.	Li YJ, etal., Hum Mol Genet 2003 Dec 15;12(24):3259-67. Epub 2003 Oct 21.
3.	Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease.	Ozturk A, etal., Neurobiol Aging. 2005 Aug-Sep;26(8):1161-5. Epub 2004 Dec 18.
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
6.	GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients.	Polimanti R, etal., Clin Exp Pharmacol Physiol. 2010 Aug;37(8):870-2. Epub 2010 Mar 30.
7.	GOA pipeline	RGD automated data pipeline
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Glutathione S-transferase: genetics and role in toxicology.	Strange RC, etal., Toxicol Lett 2000 Mar 15;112-113:357-63.
10.	Glutathione S-transferase mu, omega, pi, and theta class variants and smoking in Parkinson's disease.	Wahner AD, etal., Neurosci Lett. 2007 Feb 21;413(3):274-8. Epub 2006 Dec 27.

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:15970797	PMID:19056867	PMID:25416956

Genomics

Comparative Map Data

Gsto2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	256,673,376 - 256,695,154 (+)	NCBI		GRCr8
mRatBN7.2	1	246,731,314 - 246,757,592 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	246,732,089 - 246,753,866 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	254,859,384 - 254,881,207 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	261,552,355 - 261,574,175 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	254,202,420 - 254,224,048 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	267,617,517 - 267,640,455 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	267,607,416 - 267,640,455 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	1	271,229,036 - 271,243,517 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	275,050,163 - 275,072,303 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Rnor_5.0	1	278,656,945 - 278,671,426 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	253,239,392 - 253,275,110 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	253,504,135 - 253,539,851 (+)	NCBI
Celera	1	242,496,974 - 242,517,641 (+)	NCBI		Celera
Cytogenetic Map	1	q54	NCBI

GSTO2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	104,269,184 - 104,304,950 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	104,268,873 - 104,304,950 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	106,028,942 - 106,064,708 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	106,018,621 - 106,049,166 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	10	99,769,465 - 99,799,992 (+)	NCBI		Celera
Cytogenetic Map	10	q25.1	NCBI
HuRef	10	99,660,411 - 99,690,935 (+)	NCBI		HuRef
CHM1_1	10	106,312,517 - 106,343,025 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	105,157,320 - 105,193,113 (+)	NCBI		T2T-CHM13v2.0

Gsto2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	47,853,879 - 47,874,747 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	47,853,973 - 47,874,763 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	47,865,438 - 47,886,308 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	47,865,534 - 47,886,324 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	47,940,284 - 47,960,795 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	47,919,114 - 47,939,616 (+)	NCBI		MGSCv36	mm8
Celera	19	48,626,289 - 48,646,818 (+)	NCBI		Celera
Cytogenetic Map	19	D1	NCBI
cM Map	19	40.41	NCBI

GSTO2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	116,153,709 - 116,185,499 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	116,159,053 - 116,190,832 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	100,868,109 - 100,901,013 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	104,326,174 - 104,357,604 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	104,326,175 - 104,357,604 (+)	Ensembl	panpan1.1		panPan2

GSTO2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	16,580,250 - 16,604,977 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	16,586,777 - 16,604,976 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	16,752,960 - 16,777,367 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	17,058,781 - 17,083,140 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	17,064,468 - 17,083,139 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	16,606,330 - 16,630,694 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	16,635,026 - 16,659,336 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	16,773,733 - 16,798,027 (+)	NCBI		UU_Cfam_GSD_1.0

Gsto2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	30,304,171 - 30,322,114 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936600	1,907,517 - 1,925,235 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936600	1,907,396 - 1,925,256 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GSTO2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	115,217,879 - 115,251,435 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	115,218,179 - 115,242,377 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	125,187,089 - 125,209,743 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GSTO2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	97,319,695 - 97,348,406 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	97,325,215 - 97,349,422 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	58,438,455 - 58,468,894 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Gsto2
244 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	181
Count of miRNA genes:	110
Interacting mature miRNAs:	113
Transcripts:	ENSRNOT00000017186
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	199050459	259647894	Rat
1549910	Bw54	Body weight QTL 54		0.05	body mass (VT:0001259)	body weight (CMO:0000012)	1	214647894	259647894	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	214647894	259647894	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	222363780	260522016	Rat
631690	Scl5	Serum cholesterol level QTL 5	2.1		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	236125214	260522016	Rat
1357399	Bw45	Body weight QTL 45	3.05		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	1	206329708	251329708	Rat
1357404	Bw42	Body weight QTL 42	4.49	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	206329708	251329708	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
10053715	Scort24	Serum corticosterone level QTL 24	2.13	0.0088	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	221414816	260522016	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	216255568	260522016	Rat
1600392	Bw123	Body weight QTL 123		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	223201027	260522016	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	195804352	257091168	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
631837	Niddm35	Non-insulin dependent diabetes mellitus QTL 35		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	238699859	259647894	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
631836	Stl31	Serum triglyceride level QTL 31	4.64	5e-06	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	237147813	260522016	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	206081677	251081677	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
10059587	Bw173	Body weight QTL 173	3.23	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	1	202069611	247069611	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	228581588	259647894	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	224054293	260122809	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	225126575	260522016	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
7387289	Uae45	Urinary albumin excretion QTL 45	2.86	0.0021	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	223262787	260522016	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	224054293	260122809	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	221264111	259647894	Rat
1598839	Rf56	Renal function QTL 56			renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	245907761	257976495	Rat
1581544	Rf52	Renal function QTL 52		0.05	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	232156370	259647894	Rat
724538	Kidm1	Kidney mass QTL 1	3.2		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	213707201	252085212	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
631536	Lnnr2	Liver neoplastic nodule remodeling QTL 2	2.9	0.0005	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	1	233948574	260522016	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	224569538	260122809	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	216255568	260522016	Rat
734768	Niddm59	Non-insulin dependent diabetes mellitus QTL 59			body mass (VT:0001259)	body weight (CMO:0000012)	1	213843987	258843987	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
631669	Iddm9	Insulin dependent diabetes mellitus QTL 9	2.8	0.039	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	233190394	258625266	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	218748008	257976495	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	218753816	256448513	Rat
1358890	Bp259	Blood pressure QTL 259	3.06		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	210702053	260522016	Rat

Markers in Region

BF387299

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	246,753,680 - 246,753,860 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	271,243,329 - 271,243,508	NCBI	Rnor6.0
Rnor_6.0	1	267,640,267 - 267,640,446	NCBI	Rnor6.0
Rnor_5.0	1	278,671,238 - 278,671,417	UniSTS	Rnor5.0
Rnor_5.0	1	275,072,115 - 275,072,294	UniSTS	Rnor5.0
RGSC_v3.4	1	253,274,922 - 253,275,101	UniSTS	RGSC3.4
Celera	1	242,517,453 - 242,517,632	UniSTS
RH 3.4 Map	1	1623.8	UniSTS
Cytogenetic Map	1	q54	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
15	11	55	139	119	114	71	31	71	12	261	121	107	46	79	43

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001419742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC099075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ179406	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017186 ⟹ ENSRNOP00000017186

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	246,732,089 - 246,753,866 (+)	Ensembl
Rnor_6.0 Ensembl	1	267,618,248 - 267,640,455 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000064023 ⟹ ENSRNOP00000060669

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	246,732,089 - 246,753,866 (+)	Ensembl
Rnor_6.0 Ensembl	1	271,229,036 - 271,243,517 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076251 ⟹ ENSRNOP00000068075

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	267,618,565 - 267,627,827 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076751

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	267,618,581 - 267,638,938 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000087894 ⟹ ENSRNOP00000068891

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	267,607,416 - 267,640,402 (+)	Ensembl

RefSeq Acc Id:

NM_001012071 ⟹ NP_001012071

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,673,376 - 256,695,154 (+)	NCBI
mRatBN7.2	1	246,732,089 - 246,753,869 (+)	NCBI
Rnor_6.0	1	267,618,248 - 267,640,455 (+)	NCBI
Rnor_5.0	1	278,656,945 - 278,671,426 (+)	NCBI
RGSC_v3.4	1	253,239,392 - 253,275,110 (+)	RGD
Celera	1	242,496,974 - 242,517,641 (+)	RGD

Sequence:

show sequence

ACCGCCGGCCGCTGGGCGGGCCCTGGCGGTTCCTCGCGGATTTCCAGTAGGATGTGAGACCAGC
GGCTGAGAGGAACGGCCTGCTACCGACTTCCTCTTGCGGTAGCCCTAGATTTCCGGCCTGACTC
TCGTTTCTCTAGCTAGCTGCTGTAACGCGGTCGCCTATTGGTTCGTTCTTCCAAATGCGCCAGG
TATTGGCTGGAGCTCAGGACTCGGCGGCCAATTGCGGGTTTTGCCGTCGAGCCTGTCCATCTGT
CAGAGTTAGTTCCAGGGAAGTTAGCAGTTGCTGATCAGACCTGCATCCTCCACAGTGCAAAGTG
AGAAGCTCCTCCTTCAGCACCGCAAGGCAAGAACCCATCAACACCAGAGTGCTGTCAACCGTCG
AGAAATTGAGTTTGGATCTGGAGGGAGCTCAGCTGTGCCTGGAGCCAGCAGCAGCAGAGGTCCA
CAAGGCAGTGACTGTGAGCTTCCGGGCACTGCGTAGACACCTGGACATTGATGTCTGGGGATTT
GACAAGATGCTTGGGGAAAGGAAGCTGTCCCCCAGGGCCGGTCCCTGAGGGTGTGATCCGAATC
TACAGCATGAGGTTCTGCCCCTACTCGCACAGGACACGCCTGGTCCTCAAGGCCAAAAGCATCA
GGCATGAAATCATCAACATTAACCTGAAAAACAAGCCTGATTGGTACTATACAAAACACCCTTT
TGGCCAGGTTCCTGTCCTGGAGAACAGCCAATGTCAGCTGATCTATGAATCCGTCATTGCGTGT
GAGTACCTGGATGACGTCTTCCCAGGAAGGAAGCTGTTTCCATACGACCCATATGAACGAGCTC
GCCAGAAGATGTTATTGGAGCTATTCTGTAAGGTCCCACAGTTAAGCAAGGAATGTCTGGTAGC
GCTGAGATGTGGGAGAGACTGTACGGATCTGAAGGTTGCCCTGCGTCAGGAGTTGTGCAATCTG
GAAGAGATTCTTGAATATCAGAACACTACCTTCTTCGGTGGAGACTCTATATCCATGATTGATT
ACCTCGTCTGGCCCTGGTTTGAGCGACTGGATGTATATGGACTGGCTGACTGTGTGAATCACAC
CCCAATGCTGCGGCTCTGGATATCCTCCATGAAGCAGGACCCCGCAGTGTGCGCTCTGCACATT
GATAAGAACATTTTCCTGGGCTTCTTGAATCTCTATTTCCAAAACAACCCTTGTGCCTTTGATT
TTGGGCTGTGTGGCCCAATCGTACGGTAATCCAGTCATTGCCCAGGATTCTCCTCATATCTGAT
TCTGCATCACGGGTCATCTTGGAGTCAGTGTATTTGTTTTTTTGTTTTTTTTTTGCTTTTTTGT
TTTTTTGAGGTCCCTAATAAACATGGACGTGTAAAATATAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAA

hide sequence

RefSeq Acc Id:

NM_001419742 ⟹ NP_001406671

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,673,648 - 256,695,154 (+)	NCBI
mRatBN7.2	1	246,732,361 - 246,753,869 (+)	NCBI

RefSeq Acc Id:

XM_006231590 ⟹ XP_006231652

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,673,613 - 256,695,154 (+)	NCBI
mRatBN7.2	1	246,732,325 - 246,757,592 (+)	NCBI
Rnor_6.0	1	267,618,484 - 267,640,455 (+)	NCBI
Rnor_5.0	1	275,050,163 - 275,072,303 (+)	NCBI

Sequence:

show sequence

CCGTGCGAGAAGGGGCGGGCCCGCCTTCGCGTCGGCAGCCCGGCGACCCGACTCCGGCTTGGAG
CCGTAGCCGCCTGAAGGTTGCTCGGGGATGCCTTTTCTGCCACCGCCACTGGGTGGTTCGGTCT
CACTCGCGCTGTATCGGAAGGGAAGAGGATTTTGAGGGCTCGGTCACTGTGTTCCTTGTTTCAG
TTTTGCCGTCGAGCCTGTCCATCTGTCAGAGTTAGTTCCAGGGAAGTTAGCAGTTGCTGATCAG
ACCTGCATCCTCCACAGTGCAAAGTGAGAAGCTCCTCCTTCAGCACCGCAAGGCAAGAACCCAT
CAACACCAGAGTGCTGTCAACCGTCGAGAAATTGAGTTTGGATCTGGAGGGAGCTCAGCTGTGC
CTGGAGCCAGCAGCAGCAGAGGTCCACAAGGCAGTGACTGTGAGCTTCCGGGCACTGCGTAGAC
ACCTGGACATTGATGTCTGGGGATTTGACAAGATGCTTGGGGAAAGGAAGCTGTCCCCCAGGGC
CGGTCCCTGAGGGTGTGATCCGAATCTACAGCATGAGGTTCTGCCCCTACTCGCACAGGACACG
CCTGGTCCTCAAGGCCAAAAGCATCAGGCATGAAATCATCAACATTAACCTGAAAAACAAGCCT
GATTGGTACTATACAAAACACCCTTTTGGCCAGGTTCCTGTCCTGGAGAACAGCCAATGTCAGC
TGATCTATGAATCCGTCATTGCGTGTGAGTACCTGGATGACGTCTTCCCAGGAAGGAAGCTGTT
TCCATACGACCCATATGAACGAGCTCGCCAGAAGATGTTATTGGAGCTATTCTGTAAGGTCCCA
CAGTTAAGCAAGGAATGTCTGGTAGCGCTGAGATGTGGGAGAGACTGTACGGATCTGAAGGTTG
CCCTGCGTCAGGAGTTGTGCAATCTGGAAGAGATTCTTGAATATCAGAACACTACCTTCTTCGG
TGGAGACTCTATATCCATGATTGATTACCTCGTCTGGCCCTGGTTTGAGCGACTGGATGTATAT
GGACTGGCTGACTGTGTGAATCACACCCCAATGCTGCGGCTCTGGATATCCTCCATGAAGCAGG
ACCCCGCAGTGTGCGCTCTGCACATTGATAAGAACATTTTCCTGGGCTTCTTGAATCTCTATTT
CCAAAACAACCCTTGTGCCTTTGATTTTGGGCTGTGTGGCCCAATCGTACGGTAATCCAGTCAT
TGCCCAGGATTCTCCTCATATCTGATTCTGCATCACGGGTCATCTTGGAGTCAGTGTATTTGTT
TTTTTGTTTTTTTTTTGCTTTTTTGTTTTTTTGAGGTCCCTAATAAACATGGACGTGTAAAATA
TA

hide sequence

RefSeq Acc Id:

XM_006231592 ⟹ XP_006231654

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	256,673,427 - 256,695,154 (+)	NCBI
mRatBN7.2	1	246,731,314 - 246,757,592 (+)	NCBI
Rnor_6.0	1	267,617,517 - 267,640,455 (+)	NCBI
Rnor_5.0	1	275,050,163 - 275,072,303 (+)	NCBI

Sequence:

show sequence

CCCAAAGCCATCACCTCTGGTTTGATCCAGACTTCTAATCTAGATTTGGATTTCAAGAATGTCA
ATTTCAGATGTTCATGGGTAGAAGGGCATTAAAGATCTCCTGGAGCGGTGATACTGGCAGAGGC
CATGGGTGATGGGAACCGAATCACCCCCTGGAAGAGCAGCAAACACTTAACCGCCAAAAGATCT
CACTAGCCCCTACTTAAAATAGCCCTTTCAATCCTTCCTTCCAAATTCCGTATAAGACAGATAT
AGAGGTGTGTCATATGCAATACCACAAGATCACACCAGCCAGTTCAGTATATAAGACGGAGTGG
GTGAAATCTCTATTGGGAAAGGTTAATCGTAATACTTTTATCACTTCCACAAGAGAAGGTACTC
GGGGAGCACCTTCCCATCCTCCGGGTGATGCGGCTGGTCAAGAGCTTAAGTGAGGCCCCTAAGA
TATTGGCAGGAAGGTCTGGAAAACATACCCCGGAGGACACTGCCCTTAGCAACGGCACCCACCG
ACCGGCAGGTTTTCTGTACTTGTTTTCTGGTTTGCCTGCGAAAATCACGGGGTGATTCGTTCAG
GGCGCATAACAATCAGGCAAAGCTCAGAGCTGCATTTAGGGTTTCGCCTCCTCACAGTGCTGTG
GGGCCGCTGCACCCTGGGGAGCCAGGGATTGGCTGACTTCACAAACGGGACAACCAGCGTCCCG
CTCCGAGCGAAGCCGTCTGTGCGGCCGACCGCCGGCCGCTGGGCGGGCCCTGGCGGTTCCTCGC
GGATTTCCAGTAGGATGTGAGACCAGCGGCTGAGAGGAACGGCCTGCTACCGACTTCCTCTTGC
GGTAGCCCTAGATTTCCGGCCTGACTCTCGTTTCTCTAGCTAGCTGCTGTAACGCGGTCGCCTA
TTGGTTCGTTCTTCCAAATGCGCCAGTTTTGCCGTCGAGCCTGTCCATCTGTCAGAGTTAGTTC
CAGGGAAGTTAGCAGTTGCTGATCAGACCTGCATCCTCCACAGTGCAAAGTGAGAAGCTCCTCC
TTCAGCACCGCAAGGCAAGAACCCATCAACACCAGAGTGCTGTCAACCGTCGAGAAATTGAGTT
TGGATCTGGAGGGAGCTCAGCTGTGCCTGGAGCCAGCAGCAGCAGAGGTCCACAAGGCAGTGAC
TGTGAGCTTCCGGGCACTGCGTAGACACCTGGACATTGATGTCTGGGGATTTGACAAGATGCTT
GGGGAAAGGAAGCTGTCCCCCAGGGCCGGTCCCTGAGGGTGTGATCCGAATCTACAGCATGAGG
TTCTGCCCCTACTCGCACAGGACACGCCTGGTCCTCAAGGCCAAAAGCATCAGGCATGAAATCA
TCAACATTAACCTGAAAAACAAGCCTGATTGGTACTATACAAAACACCCTTTTGGCCAGGTTCC
TGTCCTGGAGAACAGCCAATGTCAGCTGATCTATGAATCCGTCATTGCGTGTGAGTACCTGGAT
GACGTCTTCCCAGGAAGGAAGCTGTTTCCATACGACCCATATGAACGAGCTCGCCAGAAGATGT
TATTGGAGCTATTCTGTAAGGTCCCACAGTTAAGCAAGGAATGTCTGGTAGCGCTGAGATGTGG
GAGAGACTGTACGGATCTGAAGGTTGCCCTGCGTCAGGAGTTGTGCAATCTGGAAGAGATTCTT
GAATATCAGAACACTACCTTCTTCGGTGGAGACTCTATATCCATGATTGATTACCTCGTCTGGC
CCTGGTTTGAGCGACTGGATGTATATGGACTGGCTGACTGTGTGAATCACACCCCAATGCTGCG
GCTCTGGATATCCTCCATGAAGCAGGACCCCGCAGTGTGCGCTCTGCACATTGATAAGAACATT
TTCCTGGGCTTCTTGAATCTCTATTTCCAAAACAACCCTTGTGCCTTTGATTTTGGGCTGTGTG
GCCCAATCGTACGGTAATCCAGTCATTGCCCAGGATTCTCCTCATATCTGATTCTGCATCACGG
GTCATCTTGGAGTCAGTGTATTTGTTTTTTTGTTTTTTTTTTGCTTTTTTGTTTTTTTGAGGTC
CCTAATAAACATGGACGTGTAAAATATA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001012071	(Get FASTA)	NCBI Sequence Viewer
	NP_001406671	(Get FASTA)	NCBI Sequence Viewer
	XP_006231652	(Get FASTA)	NCBI Sequence Viewer
	XP_006231654	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79295	(Get FASTA)	NCBI Sequence Viewer
	ACI32123	(Get FASTA)	NCBI Sequence Viewer
	EDL94394	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017186.4
	ENSRNOP00000060669.3
	ENSRNOP00060027006
GenBank Protein	Q6AXV9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001012071 ⟸ NM_001012071

- UniProtKB:

Q6AXV9 (UniProtKB/Swiss-Prot), B6DYQ6 (UniProtKB/TrEMBL), A0A8L2Q9F9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSGDLTRCLGKGSCPPGPVPEGVIRIYSMRFCPYSHRTRLVLKAKSIRHEIININLKNKPDWYY
TKHPFGQVPVLENSQCQLIYESVIACEYLDDVFPGRKLFPYDPYERARQKMLLELFCKVPQLSK
ECLVALRCGRDCTDLKVALRQELCNLEEILEYQNTTFFGGDSISMIDYLVWPWFERLDVYGLAD
CVNHTPMLRLWISSMKQDPAVCALHIDKNIFLGFLNLYFQNNPCAFDFGLCGPIVR

hide sequence

RefSeq Acc Id:	XP_006231654 ⟸ XM_006231592
- Peptide Label:	isoform X1
- UniProtKB:	Q6AXV9 (UniProtKB/Swiss-Prot), B6DYQ6 (UniProtKB/TrEMBL), A0A8L2Q9F9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGDLTRCLGKGSCPPGPVPEGVIRIYSMRFCPYSHRTRLVLKAKSIRHEIININLKNKPDWYY TKHPFGQVPVLENSQCQLIYESVIACEYLDDVFPGRKLFPYDPYERARQKMLLELFCKVPQLSK ECLVALRCGRDCTDLKVALRQELCNLEEILEYQNTTFFGGDSISMIDYLVWPWFERLDVYGLAD CVNHTPMLRLWISSMKQDPAVCALHIDKNIFLGFLNLYFQNNPCAFDFGLCGPIVR hide sequence

RefSeq Acc Id:	XP_006231652 ⟸ XM_006231590
- Peptide Label:	isoform X1
- UniProtKB:	Q6AXV9 (UniProtKB/Swiss-Prot), B6DYQ6 (UniProtKB/TrEMBL), A0A8L2Q9F9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGDLTRCLGKGSCPPGPVPEGVIRIYSMRFCPYSHRTRLVLKAKSIRHEIININLKNKPDWYY TKHPFGQVPVLENSQCQLIYESVIACEYLDDVFPGRKLFPYDPYERARQKMLLELFCKVPQLSK ECLVALRCGRDCTDLKVALRQELCNLEEILEYQNTTFFGGDSISMIDYLVWPWFERLDVYGLAD CVNHTPMLRLWISSMKQDPAVCALHIDKNIFLGFLNLYFQNNPCAFDFGLCGPIVR hide sequence

Ensembl Acc Id:

ENSRNOP00000068891 ⟸ ENSRNOT00000087894

Ensembl Acc Id:

ENSRNOP00000017186 ⟸ ENSRNOT00000017186

Ensembl Acc Id:

ENSRNOP00000068075 ⟸ ENSRNOT00000076251

Ensembl Acc Id:

ENSRNOP00000060669 ⟸ ENSRNOT00000064023

RefSeq Acc Id:	NP_001406671 ⟸ NM_001419742
- UniProtKB:	Q6AXV9 (UniProtKB/Swiss-Prot), B6DYQ6 (UniProtKB/TrEMBL)

Protein Domains

GST C-terminal GST N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AXV9-F1-model_v2	AlphaFold	Q6AXV9	1-248	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690983

Promoter ID:

EPDNEW_R1507

Type:

initiation region

Name:

Gsto2_1

Description:

glutathione S-transferase omega 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	267,618,506 - 267,618,566	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310764	AgrOrtholog
BioCyc Gene	G2FUF-55462	BioCyc
Ensembl Genes	ENSRNOG00000012801	Ensembl
	ENSRNOG00000049964	Ensembl
	ENSRNOG00000069697	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00060019077	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000017186.7	UniProtKB/TrEMBL
	ENSRNOT00000064023.4	UniProtKB/TrEMBL
	ENSRNOT00060033012	UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.1050.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutaredoxin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7134485	IMAGE-MGC_LOAD
InterPro	Glutathione-S-Trfase_C-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutathione-S-Trfase_C_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutathione_S-Trfase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutathione_S-Trfase_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_omega	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_Omega/HSP26	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:309465	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:94431	IMAGE-MGC_LOAD
NCBI Gene	309465	ENTREZGENE
PANTHER	GLUTATHIONE S-TRANSFERASE OMEGA-2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR43968	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	GST_C_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_N_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gsto2	PhenoGen
PRINTS	GSTRNSFRASEO	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	GST_CTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_NTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000012801	RatGTEx
	ENSRNOG00000049964	RatGTEx
	ENSRNOG00000069697	RatGTEx
	ENSRNOG00060019077	RatGTEx
Superfamily-SCOP	SSF47616	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF52833	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8L2Q9F9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QUB5_RAT	UniProtKB/TrEMBL
	B6DYQ6	ENTREZGENE, UniProtKB/TrEMBL
	GSTO2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Gsto2	glutathione S-transferase omega 2	LOC103690044	glutathione S-transferase omega-2	Data merged from RGD:9449876	737654	PROVISIONAL
2014-08-25	LOC103690044	glutathione S-transferase omega-2			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-12-06	Gsto2	glutathione S-transferase omega 2	Gsto2_predicted	glutathione S-transferase omega 2 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Gsto2_predicted	glutathione S-transferase omega 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)