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Gene: Slit1 (slit guidance ligand 1) Rattus norvegicus
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Symbol: Slit1
Name: slit guidance ligand 1
Description: Exhibits heparan sulfate proteoglycan binding activity. Involved in brain development; negative regulation of axon extension involved in axon guidance; and spinal cord development. Localizes to the extracellular space. Orthologous to human SLIT1 (slit guidance ligand 1); INTERACTS WITH 17alpha-ethynylestradiol; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MEGF4; multiple EGF-like domains protein 4; multiple epidermal growth factor-like domains 4; multiple epidermal growth factor-like domains protein 4; slit (Drosophila) homolog 1; slit homolog 1 (Drosophila); slit homolog 1 protein; slit-1
Orthologs:
Homo sapiens (human) : SLIT1 (slit guidance ligand 1)  HGNC  Alliance
Mus musculus (house mouse) : Slit1 (slit guidance ligand 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slit1 (slit guidance ligand 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLIT1 (slit guidance ligand 1)
Canis lupus familiaris (dog) : SLIT1 (slit guidance ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slit1 (slit guidance ligand 1)
Sus scrofa (pig) : SLIT1 (slit guidance ligand 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01260,843,481 - 260,992,366 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1260,843,483 - 260,992,366 (-)Ensembl
Rnor_5.01268,298,678 - 268,445,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41246,813,909 - 246,964,408 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11246,928,385 - 247,078,883 (-)NCBI
Celera1236,249,200 - 236,395,640 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slit1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69307
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.