 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations |
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
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Gene Annotator (Functional Annotation) |
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Variant Visualizer (Genomic Variants) |
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Gene Annotator (Annotation Comparison) |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway AnnotationsReferences - curated| 1. | Adams LD, etal., Arterioscler Thromb Vasc Biol 1999 Nov;19(11):2600-8. |
| 2. | Akhmanova A, etal., Cell 2001 Mar 23;104(6):923-35. |
| 3. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 4. | Morrison EE and Askham JM, Eur J Cell Biol 2001 Dec;80(12):749-53. |
| 5. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 6. | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 7. | RGD automated data pipeline |
| 8. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 9. | RGD automated import pipeline for gene-chemical interactions |
References - uncurated| PubMed | 10773885 11943150 12477932 15489334 15631994 16148041 16247022 16525027 16621792 18854161 19632184 21399614 21551097 21820309 22681889 22898821 23509069 23904609 24706950 25416956 25456071 25468996 25490267 26242911 26323690 27107012 29162697 31515488 |
Genomics
Comparative Map Data| Mapre1 (Rattus norvegicus - Norway rat) |
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| MAPRE1 (Homo sapiens - human) |
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| Mapre1 (Mus musculus - house mouse) |
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| Mapre1 (Chinchilla lanigera - long-tailed chinchilla) |
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| MAPRE1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| MAPRE1 (Canis lupus familiaris - dog) |
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| Mapre1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| MAPRE1 (Sus scrofa - pig) |
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| MAPRE1 (Chlorocebus sabaeus - African green monkey) |
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| Mapre1 (Heterocephalus glaber - naked mole-rat) |
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Position Markers| Mapre1 |
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| RH128960 |
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| Mapre1 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
| Low | |||||||||||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_138509 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006235294 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006235295 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07054351 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07054352 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01025935 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01025936 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AH005596 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC081726 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474050 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ220232 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ226262 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ230783 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ231004 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ233697 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000016220 ⟹ ENSRNOP00000016220 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000087752 ⟹ ENSRNOP00000068567 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_138509 ⟹ NP_612518 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
GTCCGACGGTTTGAACGAGACGAAGACAGAACCGGAGCCGGGCGCGCGGACTGCGGACGCGGGThide sequence |
| RefSeq Acc Id: | XM_006235294 ⟹ XP_006235356 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
GGGGGCGGAGCGTGGGCCGGAAGTGGGGGCTGCCTAGTGGTGACCGGCGAAATCTTGGCTTTGChide sequence |
| RefSeq Acc Id: | XM_006235295 ⟹ XP_006235357 | ||||||||||||
| RefSeq Status: | |||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Sequence: |
CGTGTGAGGTCATCGCGCGCGGGCGGGCGGGGTCCGACGGTTTGAACGAGACGAAGACAGAACChide sequence |
Protein Sequences| Protein RefSeqs | NP_612518 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006235356 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006235357 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAB81885 | (Get FASTA) | NCBI Sequence Viewer |
| AAH81726 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL85990 | (Get FASTA) | NCBI Sequence Viewer | |
| Q66HR2 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_612518 ⟸ NM_138509 |
| - UniProtKB: | Q66HR2 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQhide sequence |
| RefSeq Acc Id: | XP_006235357 ⟸ XM_006235295 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HR2 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQhide sequence |
| RefSeq Acc Id: | XP_006235356 ⟸ XM_006235294 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HR2 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MAVNVYSTSVTSDNLSRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQhide sequence |
| RefSeq Acc Id: | ENSRNOP00000016220 ⟸ ENSRNOT00000016220 |
| RefSeq Acc Id: | ENSRNOP00000068567 ⟸ ENSRNOT00000087752 |
Protein Domains
Calponin-homology (CH) EB1 C-terminal
TranscriptomePromoters| RGD ID: | 13692564 | ||||||||
| Promoter ID: | EPDNEW_R3089 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Mapre1_1 | ||||||||
| Description: | microtubule-associated protein, RP/EB family, member 1 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: Rnor_6.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 3 | 149226294 | 149226295 | A | G | snv | BN/SsN (MCW), WN/N (MCW) |
| 3 | 149226346 | 149226347 | G | C | snv | WKY/N (MCW), MR/N (MCW), ACI/N (MCW), Buf/N (MCW), WN/N (MCW), F344/NRrrc (MCW), M520/N (MCW), BN/SsN (MCW) |
Assembly: RGSC_v3.4
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 3 | 144125360 | 144125361 | A | G | snv | SS/JrHsdMcwi (MCW), BN/SsN (KNAW), WN/N (KNAW) |
| 3 | 144125412 | 144125413 | G | C | snv | BN/SsN (KNAW), WN/N (KNAW), BUF/N (KNAW), M520/N (KNAW), SS/JrHsdMcwi (MCW), LE/Stm (KNAW), BN/NHsdMcwi (KNAW), ACI/N (KNAW), MR/N (KNAW), FHL/EurMcwi (MCW), F344/NRrrc (KNAW), WKY/N (KNAW), SHRSP/Gcrc (MDC) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:621781 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000011798 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000016220 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOP00000068567 | UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000016220 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOT00000087752 | UniProtKB/TrEMBL | |
| Gene3D-CATH | 1.10.418.10 | UniProtKB/Swiss-Prot |
| 1.20.5.1160 | UniProtKB/Swiss-Prot | |
| IMAGE_CLONE | IMAGE:7192469 | IMAGE-MGC_LOAD |
| InterPro | CH-domain | UniProtKB/Swiss-Prot |
| CH_dom_sf | UniProtKB/Swiss-Prot | |
| EB1_C | UniProtKB/Swiss-Prot | |
| EB1_C_sf | UniProtKB/Swiss-Prot | |
| EB1_Meta | UniProtKB/Swiss-Prot | |
| IF_rod_dom_coil1B | UniProtKB/Swiss-Prot | |
| MAPRE | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:114764 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:93188 | IMAGE-MGC_LOAD |
| NCBI Gene | 114764 | ENTREZGENE |
| PANTHER | PTHR10623 | UniProtKB/Swiss-Prot |
| PTHR10623:SF20 | UniProtKB/Swiss-Prot | |
| Pfam | EB1 | UniProtKB/Swiss-Prot |
| PF00307 | UniProtKB/Swiss-Prot | |
| PhenoGen | Mapre1 | PhenoGen |
| PROSITE | EB1_C | UniProtKB/Swiss-Prot |
| PS50021 | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF140612 | UniProtKB/Swiss-Prot |
| SSF47576 | UniProtKB/Swiss-Prot | |
| UniGene | Rn.7652 | ENTREZGENE |
| UniProt | A0A0G2JT48_RAT | UniProtKB/TrEMBL |
| MARE1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2005-01-20 | Mapre1 | microtubule-associated protein, RP/EB family, member 1 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
| 2002-08-07 | Mapre1 | microtubule-associated protein, RP/EB family, member 1 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Mapre1 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 621781 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-03-04 |
| Status: | ACTIVE |
