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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1620121 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of MAPRE1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1620121 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MAPRE1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | RGD:1620121 | 6480464 | Estradiol results in increased expression of MAPRE1 mRNA | CTD | PMID:14664709 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1620121 | 6480464 | Tetrachlorodibenzodioxin affects the expression of MAPRE1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1353139 | 6480464 | Tetrachlorodibenzodioxin affects the expression of MAPRE1 mRNA | CTD | PMID:22574217 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:19954255 | 2-hydroxypropanoic acid | increases expression | ISO | RGD:1353139 | 6480464 | Lactic Acid results in increased expression of MAPRE1 mRNA | CTD | PMID:30851411 | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of MAPRE1 mRNA | CTD | PMID:21061450 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:1620121 | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of MAPRE1 mRNA | CTD | PMID:18648102 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1620121 | 6480464 | Fenretinide results in increased expression of MAPRE1 mRNA | CTD | PMID:28973697 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:1620121 | 6480464 | Fenretinide results in decreased expression of MAPRE1 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of MAPRE1 mRNA | CTD | PMID:24780913 | aflatoxin B1 | increases expression | ISO | RGD:1353139 | 6480464 | Aflatoxin B1 results in increased expression of MAPRE1 mRNA | CTD | PMID:27153756 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of MAPRE1 mRNA | CTD | PMID:16483693 | aristolochic acid | decreases expression | ISO | RGD:1353139 | 6480464 | aristolochic acid I results in decreased expression of MAPRE1 mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | RGD:1620121 | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of MAPRE1 mRNA | CTD | PMID:23650126 | arsenous acid | increases expression | ISO | RGD:1353139 | 6480464 | Arsenic Trioxide results in increased expression of MAPRE1 mRNA | CTD | PMID:20458559 | benzatropine | decreases expression | ISO | RGD:1353139 | 6480464 | Benztropine results in decreased expression of MAPRE1 protein | CTD | PMID:34122009 | benzo[a]pyrene | decreases methylation | ISO | RGD:1353139 | 6480464 | Benzo(a)pyrene results in decreased methylation of MAPRE1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | RGD:1353139 | 6480464 | Benzo(a)pyrene results in increased expression of MAPRE1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | RGD:1353139 | 6480464 | Benzo(a)pyrene affects the methylation of MAPRE1 promoter | CTD | PMID:27901495 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MAPRE1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases methylation | ISO | RGD:1353139 | 6480464 | bisphenol A results in decreased methylation of MAPRE1 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | RGD:1620121 | 6480464 | bisphenol A results in decreased expression of MAPRE1 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MAPRE1 mRNA | CTD | PMID:30816183 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of MAPRE1 gene | CTD | PMID:28505145 | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of MAPRE1 mRNA | CTD | PMID:24136188 | cadmium atom | multiple interactions | ISO | RGD:1353139 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MAPRE1 protein | CTD | PMID:33040242 | cadmium dichloride | increases expression | ISO | RGD:1620121 | 6480464 | Cadmium Chloride results in increased expression of MAPRE1 mRNA | CTD | PMID:20883709 | cadmium dichloride | multiple interactions | ISO | RGD:1353139 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MAPRE1 protein | CTD | PMID:33040242 | carbon nanotube | affects expression | ISO | RGD:1620121 | 6480464 | Nanotubes, Carbon affects the expression of MAPRE1 mRNA | CTD | PMID:25554681 | carbon nanotube | increases expression | ISO | RGD:1620121 | 6480464 | Nanotubes, Carbon analog results in increased expression of MAPRE1 mRNA | CTD | PMID:25554681 | clofibric acid | affects expression | EXP | | 6480464 | Clofibric Acid affects the expression of MAPRE1 mRNA | CTD | PMID:17602206 | clozapine | decreases expression | ISO | RGD:1353139 | 6480464 | Clozapine results in decreased expression of MAPRE1 protein | CTD | PMID:34122009 | clozapine | multiple interactions | ISO | RGD:1353139 | 6480464 | [Cuprizone co-treated with Clozapine] results in decreased expression of MAPRE1 protein | CTD | PMID:34122009 | copper(II) sulfate | increases expression | ISO | RGD:1353139 | 6480464 | Copper Sulfate results in increased expression of MAPRE1 mRNA | CTD | PMID:19549813 | Cuprizon | multiple interactions | ISO | RGD:1353139 | 6480464 | [Cuprizone co-treated with Clozapine] results in decreased expression of MAPRE1 protein, [Cuprizone co-treated with Haloperidol] results in decreased expression of MAPRE1 protein | CTD | PMID:34122009 | diarsenic trioxide | increases expression | ISO | RGD:1353139 | 6480464 | Arsenic Trioxide results in increased expression of MAPRE1 mRNA | CTD | PMID:20458559 | diethylstilbestrol | increases expression | ISO | RGD:1620121 | 6480464 | Diethylstilbestrol results in increased expression of MAPRE1 mRNA | CTD | PMID:14664709 | doxorubicin | decreases expression | ISO | RGD:1353139 | 6480464 | Doxorubicin results in decreased expression of MAPRE1 mRNA | CTD | PMID:29803840 | ethanol | affects splicing | ISO | RGD:1620121 | 6480464 | Ethanol affects the splicing of MAPRE1 mRNA | CTD | PMID:30319688 | fenthion | increases expression | ISO | RGD:1620121 | 6480464 | Fenthion results in increased expression of MAPRE1 mRNA | CTD | PMID:34813904 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of MAPRE1 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:1620121 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MAPRE1 mRNA | CTD | PMID:22206623 | folic acid | decreases expression | ISO | RGD:1620121 | 6480464 | Folic Acid results in decreased expression of MAPRE1 mRNA | CTD | PMID:25629700 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of MAPRE1 mRNA | CTD | PMID:22061828 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of MAPRE1 mRNA | CTD | PMID:24136188 | haloperidol | multiple interactions | ISO | RGD:1353139 | 6480464 | [Cuprizone co-treated with Haloperidol] results in decreased expression of MAPRE1 protein | CTD | PMID:34122009 | ivermectin | decreases expression | ISO | RGD:1353139 | 6480464 | Ivermectin results in decreased expression of MAPRE1 protein | CTD | PMID:32959892 | mitomycin C | increases expression | ISO | RGD:1353139 | 6480464 | Mitomycin results in increased expression of MAPRE1 mRNA | CTD | PMID:12760830 | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of MAPRE1 gene | CTD | PMID:33148267 | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of MAPRE1 mRNA | CTD | PMID:19638242 | nickel atom | increases expression | ISO | RGD:1353139 | 6480464 | Nickel results in increased expression of MAPRE1 mRNA | CTD | PMID:24768652, PMID:25583101 | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of MAPRE1 mRNA | CTD | PMID:22546817 | Nivalenol | increases expression | ISO | RGD:1620121 | 6480464 | nivalenol results in increased expression of MAPRE1 mRNA | CTD | PMID:35016910 | ochratoxin A | decreases expression | ISO | RGD:1353139 | 6480464 | ochratoxin A results in decreased expression of MAPRE1 mRNA | CTD | PMID:19287073, PMID:29098329 | ochratoxin A | decreases acetylation | ISO | RGD:1353139 | 6480464 | ochratoxin A results in decreased acetylation of MAPRE1 promoter | CTD | PMID:29098329 | ochratoxin A | multiple interactions | ISO | RGD:1353139 | 6480464 | [ochratoxin A results in decreased acetylation of MAPRE1 promoter] which results in decreased expression of MAPRE1 mRNA | CTD | PMID:29098329 | paclitaxel | multiple interactions | ISO | RGD:1353139 | 6480464 | olesoxime inhibits the reaction [Paclitaxel results in decreased localization of MAPRE1 protein] | CTD | PMID:20417191 | paclitaxel | decreases localization | ISO | RGD:1353139 | 6480464 | Paclitaxel results in decreased localization of MAPRE1 protein | CTD | PMID:20417191 | paracetamol | affects expression | ISO | RGD:1620121 | 6480464 | Acetaminophen affects the expression of MAPRE1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | RGD:1353139 | 6480464 | Acetaminophen results in increased expression of MAPRE1 mRNA | CTD | PMID:21420995 | pentachlorophenol | increases expression | ISO | RGD:1620121 | 6480464 | Pentachlorophenol results in increased expression of MAPRE1 mRNA | CTD | PMID:23892564 | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of MAPRE1 gene | CTD | PMID:33148267 | phenobarbital | affects expression | ISO | RGD:1353139 | 6480464 | Phenobarbital affects the expression of MAPRE1 mRNA | CTD | PMID:19159669 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of MAPRE1 mRNA | CTD | PMID:19162173 | poly(I:C) | multiple interactions | EXP | | 6480464 | [Poly I-C co-treated with HU 211] results in decreased expression of MAPRE1 mRNA | CTD | PMID:26923065 | rac-lactic acid | increases expression | ISO | RGD:1353139 | 6480464 | Lactic Acid results in increased expression of MAPRE1 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | RGD:1353139 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of MAPRE1 mRNA | CTD | PMID:23557933 | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of MAPRE1 mRNA | CTD | PMID:22431001 | sodium arsenate | increases expression | ISO | RGD:1620121 | 6480464 | sodium arsenate results in increased expression of MAPRE1 mRNA | CTD | PMID:21795629, PMID:30953684 | sodium arsenate | decreases expression | ISO | RGD:1620121 | 6480464 | sodium arsenate results in decreased expression of MAPRE1 mRNA | CTD | PMID:21795629 | sodium arsenite | increases expression | ISO | RGD:1353139 | 6480464 | sodium arsenite results in increased expression of MAPRE1 mRNA | CTD | PMID:12760830 | sodium arsenite | increases expression | ISO | RGD:1620121 | 6480464 | sodium arsenite results in increased expression of MAPRE1 mRNA | CTD | PMID:20883709 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of MAPRE1 mRNA | CTD | PMID:25993096 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of MAPRE1 mRNA | CTD | PMID:19281266 | tetrachloromethane | multiple interactions | EXP | | 6480464 | [Olive Oil analog co-treated with Carbon Tetrachloride] affects the expression of MAPRE1 protein | CTD | PMID:25303780 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of MAPRE1 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of MAPRE1 mRNA | CTD | PMID:23411599, PMID:34492290 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of MAPRE1 mRNA | CTD | PMID:33387578 | valproic acid | decreases expression | ISO | RGD:1620121 | 6480464 | Valproic Acid results in decreased expression of MAPRE1 mRNA | CTD | PMID:21427059 | valproic acid | affects expression | ISO | RGD:1353139 | 6480464 | Valproic Acid affects the expression of MAPRE1 mRNA | CTD | PMID:25979313 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of MAPRE1 mRNA | CTD | PMID:19015723 | vincristine | decreases localization | ISO | RGD:1353139 | 6480464 | Vincristine results in decreased localization of MAPRE1 protein | CTD | PMID:20417191 | vincristine | multiple interactions | ISO | RGD:1353139 | 6480464 | olesoxime inhibits the reaction [Vincristine results in decreased localization of MAPRE1 protein] | CTD | PMID:20417191 | zinc atom | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of MAPRE1 mRNA | CTD | PMID:19111725 | zinc(0) | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of MAPRE1 mRNA | CTD | PMID:19111725 | |