Mapre1 (microtubule-associated protein, RP/EB family, member 1) - Rat Genome Database

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Gene: Mapre1 (microtubule-associated protein, RP/EB family, member 1) Rattus norvegicus
Analyze
Symbol: Mapre1
Name: microtubule-associated protein, RP/EB family, member 1
RGD ID: 621781
Description: Enables microtubule plus-end binding activity. Predicted to be involved in several processes, including microtubule cytoskeleton organization; protein localization to microtubule; and regulation of microtubule polymerization. Predicted to act upstream of or within non-motile cilium assembly; positive regulation of microtubule plus-end binding activity; and protein localization to centrosome. Predicted to be located in several cellular components, including cell projection membrane; focal adhesion; and microtubule cytoskeleton. Predicted to be active in microtubule cytoskeleton. Predicted to colocalize with spindle. Orthologous to human MAPRE1 (microtubule associated protein RP/EB family member 1); PARTICIPATES IN N-cadherin signaling pathway; INTERACTS WITH 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2-methoxyethanol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: adenomatosis polyposis coli binding protein Eb1; APC-binding protein EB1; Eb1; end-binding protein 1; microtubule-associated protein RP/EB family member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23142,218,846 - 142,246,990 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3142,212,955 - 142,246,983 (+)Ensembl
Rnor_6.03149,221,346 - 149,249,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3149,221,377 - 149,249,273 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03155,599,578 - 155,627,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43144,120,532 - 144,148,856 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13144,030,965 - 144,040,482 (+)NCBI
Celera3140,960,310 - 140,988,053 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation. Adams LD, etal., Arterioscler Thromb Vasc Biol 1999 Nov;19(11):2600-8.
2. Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts. Akhmanova A, etal., Cell 2001 Mar 23;104(6):923-35.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. EB 1 immunofluorescence reveals an increase in growing astral microtubule length and number during anaphase in NRK-52E cells. Morrison EE and Askham JM, Eur J Cell Biol 2001 Dec;80(12):749-53.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10773885   PMID:11943150   PMID:12477932   PMID:15489334   PMID:15631994   PMID:16148041   PMID:16247022   PMID:16525027   PMID:16621792   PMID:17600711   PMID:18854161   PMID:19632184  
PMID:21399614   PMID:21551097   PMID:21820309   PMID:22681889   PMID:22898821   PMID:23509069   PMID:23904609   PMID:24706950   PMID:25416956   PMID:25456071   PMID:25468996   PMID:25490267  
PMID:26242911   PMID:26323690   PMID:27107012   PMID:29162697   PMID:31515488   PMID:31909540  


Genomics

Comparative Map Data
Mapre1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23142,218,846 - 142,246,990 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3142,212,955 - 142,246,983 (+)Ensembl
Rnor_6.03149,221,346 - 149,249,469 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3149,221,377 - 149,249,273 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03155,599,578 - 155,627,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43144,120,532 - 144,148,856 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13144,030,965 - 144,040,482 (+)NCBI
Celera3140,960,310 - 140,988,053 (+)NCBICelera
Cytogenetic Map3q41NCBI
MAPRE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382032,819,777 - 32,850,405 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2032,819,954 - 32,850,405 (+)EnsemblGRCh38hg38GRCh38
GRCh372031,407,760 - 31,438,211 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362030,871,435 - 30,901,867 (+)NCBINCBI36hg18NCBI36
Build 342030,871,434 - 30,901,865NCBI
Celera2028,161,619 - 28,192,142 (+)NCBI
Cytogenetic Map20q11.21NCBI
HuRef2028,194,932 - 28,225,450 (+)NCBIHuRef
CHM1_12031,311,126 - 31,341,645 (+)NCBICHM1_1
T2T-CHM13v2.02034,546,632 - 34,577,086 (+)NCBI
Mapre1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392153,583,131 - 153,615,237 (+)NCBIGRCm39mm39
GRCm39 Ensembl2153,583,194 - 153,615,230 (+)Ensembl
GRCm382153,741,287 - 153,773,317 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2153,741,274 - 153,773,310 (+)EnsemblGRCm38mm10GRCm38
MGSCv372153,567,023 - 153,599,053 (+)NCBIGRCm37mm9NCBIm37
MGSCv362153,432,817 - 153,459,666 (+)NCBImm8
Celera2159,584,963 - 159,618,551 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map275.95NCBI
Mapre1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542228,346,495 - 28,358,513 (-)NCBIChiLan1.0ChiLan1.0
MAPRE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12030,222,155 - 30,252,440 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2030,222,155 - 30,252,440 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02029,103,963 - 29,134,439 (+)NCBIMhudiblu_PPA_v0panPan3
MAPRE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12422,130,125 - 22,163,913 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2422,130,125 - 22,238,109 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2421,776,007 - 21,809,774 (+)NCBI
ROS_Cfam_1.02422,817,207 - 22,851,001 (+)NCBI
ROS_Cfam_1.0 Ensembl2422,817,183 - 22,850,998 (+)Ensembl
UMICH_Zoey_3.12422,093,309 - 22,125,926 (+)NCBI
UNSW_CanFamBas_1.02422,201,769 - 22,235,563 (+)NCBI
UU_Cfam_GSD_1.02422,632,807 - 22,666,569 (+)NCBI
Mapre1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640171,153,341 - 171,176,673 (+)NCBI
SpeTri2.0NW_00493648519,577,859 - 19,608,036 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPRE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1736,387,062 - 36,426,417 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11736,390,698 - 36,426,435 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21741,327,542 - 41,359,142 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAPRE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1237,191,848 - 37,225,454 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl237,205,654 - 37,223,784 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605089,679,921 - 89,713,248 (-)NCBIVero_WHO_p1.0
Mapre1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248426,416,877 - 6,444,043 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Mapre1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2841,242,476 - 41,243,345 (+)MAPPERmRatBN7.2
Rnor_6.0845,050,043 - 45,050,911NCBIRnor6.0
Rnor_5.0843,536,857 - 43,537,725UniSTSRnor5.0
RGSC_v3.43144,147,572 - 144,147,719UniSTSRGSC3.4
Celera840,841,755 - 40,842,623UniSTS
Cytogenetic Map8q22UniSTS
Cytogenetic Map3q41UniSTS
RH128960  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23142,245,527 - 142,245,723 (+)MAPPERmRatBN7.2
Rnor_6.03149,248,007 - 149,248,202NCBIRnor6.0
Rnor_5.03155,626,225 - 155,626,420UniSTSRnor5.0
RGSC_v3.43144,147,571 - 144,147,766UniSTSRGSC3.4
Celera3140,986,768 - 140,986,963UniSTS
Cytogenetic Map3q41UniSTS
Mapre1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23142,245,528 - 142,245,676 (+)MAPPERmRatBN7.2
Rnor_6.03149,248,008 - 149,248,155NCBIRnor6.0
Rnor_5.03155,626,226 - 155,626,373UniSTSRnor5.0
RGSC_v3.43144,147,572 - 144,147,719UniSTSRGSC3.4
Celera3140,986,769 - 140,986,916UniSTS
Cytogenetic Map3q41UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1581546Pur13Proteinuria QTL 132.930.0335total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3140069424146976080Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:222
Count of miRNA genes:129
Interacting mature miRNAs:184
Transcripts:ENSRNOT00000016220
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000016220   ⟹   ENSRNOP00000016220
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3142,218,901 - 142,246,983 (+)Ensembl
Rnor_6.0 Ensembl3149,221,377 - 149,249,273 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087752   ⟹   ENSRNOP00000068567
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3142,218,863 - 142,244,362 (+)Ensembl
Rnor_6.0 Ensembl3149,221,409 - 149,237,224 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110766   ⟹   ENSRNOP00000096433
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3142,212,955 - 142,246,983 (+)Ensembl
RefSeq Acc Id: NM_138509   ⟹   NP_612518
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23142,218,889 - 142,246,813 (+)NCBI
Rnor_6.03149,221,377 - 149,249,292 (+)NCBI
Rnor_5.03155,599,578 - 155,627,687 (+)NCBI
RGSC_v3.43144,120,532 - 144,148,856 (+)RGD
Celera3140,960,310 - 140,988,053 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235294   ⟹   XP_006235356
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23142,219,069 - 142,246,990 (+)NCBI
Rnor_6.03149,221,614 - 149,249,469 (+)NCBI
Rnor_5.03155,599,578 - 155,627,687 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235295   ⟹   XP_006235357
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23142,218,846 - 142,246,990 (+)NCBI
Rnor_6.03149,221,346 - 149,249,469 (+)NCBI
Rnor_5.03155,599,578 - 155,627,687 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104099   ⟹   XP_038960027
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23142,219,169 - 142,246,990 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_612518   ⟸   NM_138509
- UniProtKB: Q66HR2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006235357   ⟸   XM_006235295
- Peptide Label: isoform X1
- UniProtKB: Q66HR2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006235356   ⟸   XM_006235294
- Peptide Label: isoform X1
- UniProtKB: Q66HR2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016220   ⟸   ENSRNOT00000016220
RefSeq Acc Id: ENSRNOP00000068567   ⟸   ENSRNOT00000087752
RefSeq Acc Id: XP_038960027   ⟸   XM_039104099
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000096433   ⟸   ENSRNOT00000110766
Protein Domains
Calponin-homology (CH)   EB1 C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66HR2-F1-model_v2 AlphaFold Q66HR2 1-268 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692564
Promoter ID:EPDNEW_R3089
Type:initiation region
Name:Mapre1_1
Description:microtubule-associated protein, RP/EB family, member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03149,221,404 - 149,221,464EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
3 149226294 149226295 A G snv BN/SsN (MCW), WN/N (MCW)
3 149226346 149226347 G C snv WN/N (MCW), F344/NRrrc (MCW), M520/N (MCW), MR/N (MCW), WKY/N (MCW), BN/SsN (MCW), ACI/N (MCW), Buf/N (MCW)


Assembly: RGSC_v3.4
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
3 144125360 144125361 A G snv BN/SsN (KNAW), SS/JrHsdMcwi (MCW), WN/N (KNAW)
3 144125412 144125413 G C snv BN/SsN (KNAW), BN/NHsdMcwi (KNAW), BUF/N (KNAW), F344/NRrrc (KNAW), LE/Stm (KNAW), M520/N (KNAW), MR/N (KNAW), WKY/N (KNAW), WN/N (KNAW), ACI/N (KNAW), SHRSP/Gcrc (MDC), FHL/EurMcwi (MCW), SS/JrHsdMcwi (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621781 AgrOrtholog
BioCyc Gene G2FUF-47208 BioCyc
Ensembl Genes ENSRNOG00000011798 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000016220 ENTREZGENE
  ENSRNOP00000068567 ENTREZGENE
  ENSRNOP00000068567.2 UniProtKB/TrEMBL
  ENSRNOP00000096433 ENTREZGENE
  ENSRNOP00000096433.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016220 ENTREZGENE
  ENSRNOT00000087752 ENTREZGENE
  ENSRNOT00000087752.2 UniProtKB/TrEMBL
  ENSRNOT00000110766 ENTREZGENE
  ENSRNOT00000110766.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192469 IMAGE-MGC_LOAD
InterPro CH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EB1_C UniProtKB/Swiss-Prot
  EB1_C_sf UniProtKB/Swiss-Prot
  EB1_Meta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAPRE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:114764 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93188 IMAGE-MGC_LOAD
NCBI Gene 114764 ENTREZGENE
PANTHER PTHR10623 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10623:SF20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EB1 UniProtKB/Swiss-Prot
  PF00307 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mapre1 PhenoGen
PROSITE EB1_C UniProtKB/Swiss-Prot
  PS50021 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF140612 UniProtKB/Swiss-Prot
  SSF47576 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JT48_RAT UniProtKB/TrEMBL
  A0A8I6GM28_RAT UniProtKB/TrEMBL
  MARE1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Mapre1  microtubule-associated protein, RP/EB family, member 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Mapre1  microtubule-associated protein, RP/EB family, member 1      Symbol and Name status set to provisional 70820 PROVISIONAL