![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Itgbl1 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Itgbl1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ITGBL1 mRNA | CTD | PMID:36331819 | Itgbl1 | Rat | 1,2-dichloroethane | decreases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of ITGBL1 mRNA | CTD | PMID:28960355 | Itgbl1 | Rat | 17beta-estradiol | multiple interactions | ISO | ITGBL1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of ITGBL1 mRNA more ... | CTD | PMID:17404688 more ... | Itgbl1 | Rat | 17beta-estradiol | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ITGBL1 mRNA | CTD | PMID:21795739 | Itgbl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ITGBL1 mRNA | CTD | PMID:34747641 | Itgbl1 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Itgbl1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:38648751 | Itgbl1 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of ITGBL1 mRNA | CTD | PMID:28522335 | Itgbl1 | Rat | 3-methylcholanthrene | increases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | Methylcholanthrene results in increased expression of ITGBL1 mRNA | CTD | PMID:20713471 | Itgbl1 | Rat | aflatoxin B1 | decreases methylation | ISO | ITGBL1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ITGBL1 exon more ... | CTD | PMID:27153756 and PMID:30157460 | Itgbl1 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of ITGBL1 mRNA | CTD | PMID:25378103 | Itgbl1 | Rat | Aflatoxin B2 alpha | increases methylation | ISO | ITGBL1 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of ITGBL1 intron | CTD | PMID:30157460 | Itgbl1 | Rat | arsenous acid | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of ITGBL1 mRNA | CTD | PMID:26705709 | Itgbl1 | Rat | benzo[a]pyrene | decreases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ITGBL1 mRNA | CTD | PMID:20713471 | Itgbl1 | Rat | benzo[a]pyrene | affects methylation | ISO | ITGBL1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ITGBL1 intron | CTD | PMID:30157460 | Itgbl1 | Rat | benzo[a]pyrene | increases methylation | ISO | ITGBL1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ITGBL1 exon and Benzo(a)pyrene results in increased methylation of ITGBL1 promoter | CTD | PMID:27901495 | Itgbl1 | Rat | benzo[a]pyrene | increases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ITGBL1 mRNA | CTD | PMID:22228805 | Itgbl1 | Rat | bisphenol A | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ITGBL1 mRNA | CTD | PMID:25047013 | Itgbl1 | Rat | bisphenol A | affects methylation | ISO | ITGBL1 (Homo sapiens) | 6480464 | bisphenol A affects the methylation of ITGBL1 gene | CTD | PMID:31601247 | Itgbl1 | Rat | bisphenol A | multiple interactions | ISO | ITGBL1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ITGBL1 gene | CTD | PMID:31601247 | Itgbl1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ITGBL1 mRNA | CTD | PMID:33296240 and PMID:36779543 | Itgbl1 | Rat | bisphenol A | increases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ITGBL1 mRNA | CTD | PMID:30951980 | Itgbl1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ITGBL1 mRNA | CTD | PMID:25181051 more ... | Itgbl1 | Rat | bisphenol F | increases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of ITGBL1 mRNA | CTD | PMID:30951980 | Itgbl1 | Rat | bisphenol F | decreases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of ITGBL1 mRNA | CTD | PMID:36706583 | Itgbl1 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of ITGBL1 mRNA | CTD | PMID:33453195 | Itgbl1 | Rat | cadmium dichloride | increases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of ITGBL1 mRNA | CTD | PMID:38382870 | Itgbl1 | Rat | calcitriol | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of ITGBL1 mRNA | CTD | PMID:26485663 | Itgbl1 | Rat | carbon nanotube | affects expression | ISO | Itgbl1 (Mus musculus) | 6480464 | Nanotubes and Carbon analog affects the expression of ITGBL1 mRNA | CTD | PMID:25554681 | Itgbl1 | Rat | choline | multiple interactions | ISO | Itgbl1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ITGBL1 mRNA | CTD | PMID:20938992 | Itgbl1 | Rat | copper atom | multiple interactions | ISO | ITGBL1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of ITGBL1 mRNA | CTD | PMID:20971185 | Itgbl1 | Rat | copper(0) | multiple interactions | ISO | ITGBL1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of ITGBL1 mRNA | CTD | PMID:20971185 | Itgbl1 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of ITGBL1 mRNA | CTD | PMID:26577399 | Itgbl1 | Rat | deoxynivalenol | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | deoxynivalenol results in decreased expression of ITGBL1 mRNA | CTD | PMID:31863870 | Itgbl1 | Rat | dexamethasone | increases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | Dexamethasone results in increased expression of ITGBL1 mRNA | CTD | PMID:22733784 | Itgbl1 | Rat | diarsenic trioxide | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of ITGBL1 mRNA | CTD | PMID:26705709 | Itgbl1 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of ITGBL1 mRNA | CTD | PMID:33729688 | Itgbl1 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of ITGBL1 mRNA | CTD | PMID:25152437 | Itgbl1 | Rat | doxorubicin | decreases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of ITGBL1 mRNA | CTD | PMID:28608983 | Itgbl1 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of ITGBL1 mRNA | CTD | PMID:29391264 | Itgbl1 | Rat | folic acid | multiple interactions | ISO | Itgbl1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ITGBL1 mRNA | CTD | PMID:20938992 | Itgbl1 | Rat | folic acid | increases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Folic Acid results in increased expression of ITGBL1 mRNA | CTD | PMID:21867686 | Itgbl1 | Rat | fulvestrant | multiple interactions | ISO | ITGBL1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ITGBL1 gene | CTD | PMID:31601247 | Itgbl1 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of ITGBL1 mRNA | CTD | PMID:27387713 | Itgbl1 | Rat | genistein | increases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | Genistein results in increased expression of ITGBL1 mRNA | CTD | PMID:32186404 | Itgbl1 | Rat | ibuprofen | affects expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Ibuprofen affects the expression of ITGBL1 mRNA | CTD | PMID:17070997 | Itgbl1 | Rat | inulin | multiple interactions | ISO | Itgbl1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ITGBL1 mRNA | CTD | PMID:36331819 | Itgbl1 | Rat | isoprenaline | increases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of ITGBL1 mRNA | CTD | PMID:20003209 | Itgbl1 | Rat | L-methionine | multiple interactions | ISO | Itgbl1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ITGBL1 mRNA | CTD | PMID:20938992 | Itgbl1 | Rat | lead diacetate | decreases expression | EXP | | 6480464 | lead acetate results in decreased expression of ITGBL1 mRNA | CTD | PMID:11578147 | Itgbl1 | Rat | methotrexate | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Methotrexate results in decreased expression of ITGBL1 mRNA | CTD | PMID:24657277 | Itgbl1 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ITGBL1 gene | CTD | PMID:35440735 | Itgbl1 | Rat | mifepristone | decreases expression | EXP | | 6480464 | Mifepristone results in decreased expression of ITGBL1 mRNA | CTD | PMID:25972201 | Itgbl1 | Rat | nickel atom | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of ITGBL1 mRNA | CTD | PMID:24768652 and PMID:25583101 | Itgbl1 | Rat | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ITGBL1 mRNA | CTD | PMID:37871705 | Itgbl1 | Rat | PD 0325901 | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | mirdametinib results in decreased expression of ITGBL1 mRNA | CTD | PMID:25119042 | Itgbl1 | Rat | PD 0325901 | multiple interactions | ISO | ITGBL1 (Homo sapiens) | 6480464 | [(+)-JQ1 compound co-treated with mirdametinib] results in decreased expression of ITGBL1 mRNA | CTD | PMID:25119042 | Itgbl1 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of ITGBL1 mRNA | CTD | PMID:37995155 | Itgbl1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Itgbl1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ITGBL1 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ITGBL1 mRNA | CTD | PMID:36331819 | Itgbl1 | Rat | perfluorooctanoic acid | decreases expression | ISO | Itgbl1 (Mus musculus) | 6480464 | perfluorooctanoic acid results in decreased expression of ITGBL1 mRNA | CTD | PMID:31904477 | Itgbl1 | Rat | potassium chromate | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of ITGBL1 mRNA | CTD | PMID:22714537 | Itgbl1 | Rat | progesterone | multiple interactions | ISO | ITGBL1 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of ITGBL1 mRNA more ... | CTD | PMID:17404688 more ... | Itgbl1 | Rat | progesterone | increases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Progesterone results in increased expression of ITGBL1 mRNA | CTD | PMID:17404688 | Itgbl1 | Rat | propanal | increases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of ITGBL1 mRNA | CTD | PMID:26079696 | Itgbl1 | Rat | resveratrol | multiple interactions | ISO | ITGBL1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of ITGBL1 mRNA | CTD | PMID:23557933 | Itgbl1 | Rat | rifampicin | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Rifampin results in decreased expression of ITGBL1 mRNA | CTD | PMID:24552687 | Itgbl1 | Rat | rofecoxib | affects expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | rofecoxib affects the expression of ITGBL1 mRNA | CTD | PMID:17070997 | Itgbl1 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of ITGBL1 mRNA | CTD | PMID:28374803 | Itgbl1 | Rat | silicon dioxide | increases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of ITGBL1 mRNA | CTD | PMID:25895662 | Itgbl1 | Rat | simvastatin | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | Simvastatin results in decreased expression of ITGBL1 mRNA | CTD | PMID:17428261 | Itgbl1 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ITGBL1 mRNA | CTD | PMID:19281266 | Itgbl1 | Rat | T-2 toxin | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | T-2 Toxin results in decreased expression of ITGBL1 mRNA | CTD | PMID:31863870 | Itgbl1 | Rat | triadimefon | decreases expression | ISO | ITGBL1 (Homo sapiens) | 6480464 | triadimefon results in decreased expression of ITGBL1 mRNA | CTD | PMID:26705709 | Itgbl1 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of ITGBL1 mRNA | CTD | PMID:33387578 | Itgbl1 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of ITGBL1 mRNA | CTD | PMID:23034163 | |