Ankrd37 (ankyrin repeat domain 37)

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Gene: Ankrd37 (ankyrin repeat domain 37) Rattus norvegicus

Analyze

Symbol:

Ankrd37

Name:

ankyrin repeat domain 37

RGD ID:

1565715

Description:

Predicted to be located in cytosol; mitochondrion; and nucleus. Predicted to be active in cytoplasm. Orthologous to human ANKRD37 (ankyrin repeat domain 37); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amphetamine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ankyrin repeat domain-containing protein 37; LOC361149; RGD1565715; similar to low density lipoprotein receptor-related protein binding protein

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANKRD37 (ankyrin repeat domain 37)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ankrd37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ankrd37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANKRD37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANKRD37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ankrd37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANKRD37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANKRD37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ankrd37 (ankyrin repeat domain 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ANKRD37 (ankyrin repeat domain 37)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ankrd37 (ankyrin repeat domain 37)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ankrd37 (ankyrin repeat domain 37)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	46,269,025 - 46,271,971 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	46,268,443 - 46,271,963 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	51,670,260 - 51,673,301 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	16	55,039,437 - 55,042,473 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	16	50,309,635 - 50,312,676 (+)	NCBI	Rnor_WKY
Rnor_6.0	16	49,463,016 - 49,465,905 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	49,462,889 - 49,465,888 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	49,189,582 - 49,192,471 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	49,549,527 - 49,552,416 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	44,267,470 - 44,270,359 (+)	NCBI		Celera
Cytogenetic Map	16	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Cerebral Visual Impairment and Intellectual Disability (ISO)

dilated cardiomyopathy (ISO)

genetic disease (ISO)

Herpes Simplex Encephalitis 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,10-phenanthroline (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-diaminotoluene (ISO)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

caffeine (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

clothianidin (ISO)

cobalt dichloride (EXP,ISO)

cobalt(2+) sulfate (ISO)

copper atom (ISO)

copper(0) (ISO)

coumarin 460 (ISO)

crotonaldehyde (ISO)

curcumin (ISO)

cyclosporin A (ISO)

deoxynivalenol (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

diphenylcyclopropenone (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethyl methanesulfonate (ISO)

fluoranthene (ISO)

formaldehyde (ISO)

indole-3-methanol (EXP)

indometacin (ISO)

iron atom (EXP,ISO)

iron(0) (EXP,ISO)

leflunomide (ISO)

lipopolysaccharide (ISO)

menadione (ISO)

methoxyacetic acid (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (EXP,ISO)

mithramycin (EXP)

Monobutylphthalate (EXP)

N-methyl-4-phenylpyridinium (EXP)

nickel dichloride (EXP,ISO)

nitrofen (EXP)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

quercetin (ISO)

quinolin-8-ol (ISO)

rac-lactic acid (ISO)

resorcinol (ISO)

rotenone (EXP,ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sotorasib (ISO)

succimer (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

thalidomide (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

trametinib (ISO)

tributylstannane (EXP)

triptonide (ISO)

troglitazone (ISO)

valproic acid (EXP,ISO)

vincristine (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc dichloride (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (IBA,ISO)

cytosol (ISO)

male germ cell nucleus (ISO)

mitochondrion (ISO)

nucleoplasm (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:21723927

Genomics

Comparative Map Data

Ankrd37
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	16	46,269,025 - 46,271,971 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	46,268,443 - 46,271,963 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	51,670,260 - 51,673,301 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	16	55,039,437 - 55,042,473 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	16	50,309,635 - 50,312,676 (+)	NCBI	Rnor_WKY
Rnor_6.0	16	49,463,016 - 49,465,905 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	49,462,889 - 49,465,888 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	49,189,582 - 49,192,471 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	49,549,527 - 49,552,416 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	44,267,470 - 44,270,359 (+)	NCBI		Celera
Cytogenetic Map	16	q11	NCBI

ANKRD37
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	185,396,841 - 185,400,723 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	4	185,396,021 - 185,400,628 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	186,317,995 - 186,321,395 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	186,554,834 - 186,558,384 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	4	183,644,030 - 183,647,577 (+)	NCBI		Celera
Cytogenetic Map	4	q35.1	NCBI
HuRef	4	182,071,296 - 182,074,843 (+)	NCBI		HuRef
CHM1_1	4	186,294,269 - 186,297,819 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	188,740,172 - 188,743,573 (+)	NCBI		T2T-CHM13v2.0

Ankrd37
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	46,449,945 - 46,453,272 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	46,449,939 - 46,458,744 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	45,996,908 - 46,000,414 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	45,996,902 - 46,005,707 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	47,082,262 - 47,085,204 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	47,495,725 - 47,498,667 (-)	NCBI		MGSCv36	mm8
Celera	8	48,679,833 - 48,682,775 (-)	NCBI		Celera
Cytogenetic Map	8	B1.1	NCBI

Ankrd37
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	23,655,716 - 23,658,009 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	23,655,501 - 23,658,069 (-)	NCBI	ChiLan1.0	ChiLan1.0

ANKRD37
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	4	189,776,194 - 189,779,945 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	189,776,184 - 189,780,053 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	4	177,559,012 - 177,563,343 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ANKRD37
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	45,230,095 - 45,233,411 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	45,230,096 - 45,233,418 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	45,717,733 - 45,721,065 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	47,446,145 - 47,449,515 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	16	45,413,967 - 45,417,336 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	46,026,797 - 46,030,138 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	46,158,191 - 46,161,564 (-)	NCBI		UU_Cfam_GSD_1.0

Ankrd37
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	34,161,993 - 34,164,625 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936554	3,944,205 - 3,948,450 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936554	3,945,343 - 3,948,155 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANKRD37
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	46,445,881 - 46,450,097 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	46,445,789 - 46,450,046 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	53,346,602 - 53,349,746 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANKRD37
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	131,348,511 - 131,352,071 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	131,347,975 - 131,353,985 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	111,608,196 - 111,613,847 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ankrd37
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624769	16,251,596 - 16,253,467 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624769	16,251,387 - 16,254,298 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ankrd37
21 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	196
Count of miRNA genes:	160
Interacting mature miRNAs:	167
Transcripts:	ENSRNOT00000039909
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	832236	59492508	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	832236	59492508	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	832236	59492508	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	832236	59492508	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4227609	46975965	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	4227609	48972724	Rat
61338	Bp23	Blood pressure QTL 23	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4227609	49227609	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4227609	60252231	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	19004435	75226532	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	21735975	66735975	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	24325513	69325513	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	25152793	70152793	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	31951520	60148445	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	35288870	80288870	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	37752156	82752156	Rat
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	37752156	82752156	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	42396345	84729064	Rat
631833	Sach2	Saccharin preference QTL 2	4	0.01	consumption behavior trait (VT:0002069)	calculated saccharin drink intake rate (CMO:0001613)	16	43024842	50166018	Rat

Markers in Region

RH131258

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	46,271,118 - 46,271,784 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	49,465,061 - 49,465,726	NCBI	Rnor6.0
Rnor_5.0	16	49,191,627 - 49,192,292	UniSTS	Rnor5.0
RGSC_v3.4	16	49,551,572 - 49,552,237	UniSTS	RGSC3.4
Celera	16	44,269,515 - 44,270,180	UniSTS
Cytogenetic Map	16	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium										12	5
Low	3	43	57	41	19	41	8	11	74	23	36	11	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005494641	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC130162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000282	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000039909 ⟹ ENSRNOP00000049105

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	46,268,443 - 46,271,963 (+)	Ensembl
Rnor_6.0 Ensembl	16	49,462,889 - 49,465,888 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000120066 ⟹ ENSRNOP00000088167

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	46,269,074 - 46,271,577 (+)	Ensembl

RefSeq Acc Id:

NM_001108400 ⟹ NP_001101870

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	16	46,269,074 - 46,271,963 (+)	NCBI
Rnor_6.0	16	49,463,016 - 49,465,905 (+)	NCBI
Rnor_5.0	16	49,189,582 - 49,192,471 (+)	NCBI
RGSC_v3.4	16	49,549,527 - 49,552,416 (+)	RGD
Celera	16	44,267,470 - 44,270,359 (+)	RGD

Sequence:

show sequence

GCACTCTTACCGACCGGTTTCGCCTCGCTGAACTCCCGGAGACACTTGTCATCTGCTTTAGGGG
GCGATGCTGTTGCTTAGCTGCAACTTGGAGGAGGATGGCCTTAAGAATTTGCTGGAGACAGGAG
CATCAGTCAACGCACCCCCGGATCCTCAAGAGCAGTCGCCTGTTCACCTAGCTGCAGGTGGCGG
CCTTGCTTGCTTTCTTCTCTGGCAGCTGCAAACCGGTGCTGACCTCAACCAACAGGATGTGTTG
GGAGAAACTCCACTCCACAAGGCAGCCAAAGTTGGAAGCCTAGAGTGCCTTAGCCTCCTGGTGG
CCAGTGATGTCCGGATTGACTTATGTAATAAAAATGGGCAAACAGCTGAAGATCTTGCTTGGTC
ATGTGGCTTTCCAGAATGTGCCAGGTTTCTAACAATGATTAAATGTACGCAGACAGCAAAATCC
TCACGTGAGCACCCTGAGGGTGACCCCTATGCTCCTGTGCTGAGACAGAAGCGGAGTTTCAGAA
CTATGGAGAGCAGAGTGTTGAAGAGAAAGTGTTGATGATGTCTTGTTGGGCAAGAGGAGAGAAG
AGGCTTGAAGACGGGCTTCACTTCAGACAGATCTATAAGCCATTGCTTTGGCTTAACACATGGC
TACACTCCTGAGGAGGAAAGCTTTCTTCCAAGTGAAGAGAAATTCATTCATGCATGTGTTTACA
TGACTAGTATTTTGGATGTACATGTTTTGTTATTTAACTTATTAAAAGAATATTCAAGCAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039094639 ⟹ XP_038950567

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	16	46,269,025 - 46,271,203 (+)	NCBI

RefSeq Acc Id:

XR_005494641

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	16	46,269,025 - 46,271,971 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101870	(Get FASTA)	NCBI Sequence Viewer
	XP_038950567	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66884	(Get FASTA)	NCBI Sequence Viewer
	EDL78869	(Get FASTA)	NCBI Sequence Viewer
	EDL78870	(Get FASTA)	NCBI Sequence Viewer
	EDL78871	(Get FASTA)	NCBI Sequence Viewer
	EDL78872	(Get FASTA)	NCBI Sequence Viewer
	EDL78873	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001101870 ⟸ NM_001108400
- UniProtKB:	B2RYS4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLLSCNLEEDGLKNLLETGASVNAPPDPQEQSPVHLAAGGGLACFLLWQLQTGADLNQQDVLG ETPLHKAAKVGSLECLSLLVASDVRIDLCNKNGQTAEDLAWSCGFPECARFLTMIKCTQTAKSS REHPEGDPYAPVLRQKRSFRTMESRVLKRKC hide sequence

RefSeq Acc Id:

ENSRNOP00000049105 ⟸ ENSRNOT00000039909

RefSeq Acc Id:	XP_038950567 ⟸ XM_039094639
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000088167 ⟸ ENSRNOT00000120066

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2RYS4-F1-model_v2	AlphaFold	B2RYS4	1-159	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700103

Promoter ID:

EPDNEW_R10626

Type:

single initiation site

Name:

Ankrd37_1

Description:

ankyrin repeat domain 37

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	49,463,014 - 49,463,074	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565715	AgrOrtholog
BioCyc Gene	G2FUF-11332	BioCyc
Ensembl Genes	ENSRNOG00000031335	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000049105.4	UniProtKB/TrEMBL
	ENSRNOP00000088167	ENTREZGENE
	ENSRNOP00000088167.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000039909.5	UniProtKB/TrEMBL
	ENSRNOT00000120066	ENTREZGENE
	ENSRNOT00000120066.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.20	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:6887335	IMAGE-MGC_LOAD
InterPro	Ankyrin_rpt	UniProtKB/TrEMBL
	Ankyrin_rpt-contain_sf	UniProtKB/TrEMBL
KEGG Report	rno:361149	UniProtKB/TrEMBL
MGC_CLONE	MGC:188821	IMAGE-MGC_LOAD
NCBI Gene	361149	ENTREZGENE
PANTHER	ANK_REP_REGION DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 37	UniProtKB/TrEMBL
Pfam	Ank_2	UniProtKB/TrEMBL
PhenoGen	Ankrd37	PhenoGen
PROSITE	ANK_REP_REGION	UniProtKB/TrEMBL
	ANK_REPEAT	UniProtKB/TrEMBL
SMART	ANK	UniProtKB/TrEMBL
Superfamily-SCOP	ANK	UniProtKB/TrEMBL
UniProt	A0A8I6A8T4_RAT	UniProtKB/TrEMBL
	B2RYS4	ENTREZGENE, UniProtKB/TrEMBL
	F7EMG3_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Ankrd37	ankyrin repeat domain 37	RGD1565715_predicted	similar to low density lipoprotein receptor-related protein binding protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1565715_predicted	similar to low density lipoprotein receptor-related protein binding protein (predicted)	LOC361149	similar to low density lipoprotein receptor-related protein binding protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC361149	similar to low density lipoprotein receptor-related protein binding protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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