Gan (gigaxonin) - Rat Genome Database

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Gene: Gan (gigaxonin) Rattus norvegicus
Analyze
Symbol: Gan
Name: gigaxonin
RGD ID: 1307766
Description: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in giant axonal neuropathy 1. Orthologous to human GAN (gigaxonin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: giant axonal neuropathy; LOC307893
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81962,116,600 - 62,173,879 (+)NCBIGRCr8
mRatBN7.21945,207,783 - 45,265,066 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1945,207,184 - 45,254,107 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1952,017,893 - 52,064,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01952,670,909 - 52,717,223 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01954,915,137 - 54,961,451 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01949,692,790 - 49,746,178 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1949,695,579 - 49,741,965 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01960,480,642 - 60,533,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41947,263,532 - 47,310,683 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11947,268,492 - 47,315,557 (+)NCBI
Celera1944,479,857 - 44,526,017 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 10 of 10 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GanRatCharcot-Marie-Tooth disease  ISORGD:13171478554872ClinVar Annotator: match by term: Charcot-Marie-Tooth diseaseClinVarPMID:24627108|PMID:25025039|PMID:25741868|PMID:28492532
GanRatdevelopmental and epileptic encephalopathy 1  ISORGD:13171478554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy, 1ClinVarPMID:28492532|PMID:31780880
GanRatfamilial cold autoinflammatory syndrome 3  ISORGD:13171478554872ClinVar Annotator: match by term: Familial cold autoinflammatory syndrome 3ClinVarPMID:28492532
GanRatgenetic disease  ISORGD:13171478554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:11062483|PMID:12655563|PMID:12668605|PMID:14718689|PMID:16199547|PMID:17331252|PMID:17576681|PMID:17578852|PMID:20949505|PMID:23248352|PMID:23332420|PMID:23585478|PMID:23890932|PMID:24758703|PMID:25025039|PMID:25741868|PMID:28492532|PMID:32999401|PMID:34114613|PMID:37273706|PMID:37712079|PMID:9536098
GanRatGiant Axonal Neuropathy  ISORGD:13171478554872ClinVar Annotator: match by term: Giant axonal neuropathyClinVarPMID:14718689|PMID:16565160|PMID:17578852|PMID:25741868|PMID:28492532|PMID:34114613|PMID:37273706|PMID:37712079
GanRatgiant axonal neuropathy 1  ISORGD:13171478554872ClinVar Annotator: match by term: Giant axonal neuropathy 1ClinVarPMID:11053687|PMID:11062483|PMID:11971098|PMID:12655563|PMID:12668605|PMID:14718689|PMID:15897506|PMID:16199547|PMID:17331252|PMID:17576681|PMID:17578852|PMID:17587580|PMID:19231187|PMID:19295179|PMID:20949505|PMID:21356581|PMID:2153943|PMID:23248352|PMID:23316953|PMID:23332420|PMID:23585478|PMID:23890932|PMID:24464710|PMID:24627108|PMID:24758703|PMID:25025039|PMID:25040701|PMID:25326635|PMID:25741868|PMID:26392352|PMID:28492532|PMID:29876741|PMID:30246730|PMID:30373780|PMID:30532362|PMID:31655922|PMID:31771860|PMID:32158379|PMID:32999401|PMID:34114613|PMID:37273706|PMID:37673932|PMID:37712079|PMID:38703036|PMID:9536098
GanRatintellectual disability  ISORGD:13171478554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:30167849
GanRatMuscle Hypotonia  ISORGD:13171478554872ClinVar Annotator: match by term: HypotoniaClinVar 
GanRatneuropathy  ISORGD:13171478554872ClinVar Annotator: match by term: Peripheral neuropathyClinVarPMID:24758703|PMID:25741868|PMID:28492532
GanRatperipheral nervous system disease  ISORGD:13171478554872ClinVar Annotator: match by term: Peripheral neuropathyClinVarPMID:24758703|PMID:25741868|PMID:28492532
1 to 10 of 10 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GanRatGiant Axonal Neuropathy  ISORGD:131714711554173CTD Direct Evidence: marker/mechanismCTD 
GanRatperipheral nervous system disease  ISORGD:131714711554173CTD Direct Evidence: marker/mechanismCTDPMID:19398414
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GanRatgiant axonal neuropathy 1  ISSRGD:131714813592920OMIM:256850MouseDO 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GanRatgiant axonal neuropathy 1  ISORGD:13171477240710 OMIM 

1 to 20 of 54 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GanRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:13171486480464Tetrachlorodibenzodioxin affects the expression of GAN mRNACTDPMID:21570461
GanRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of GAN mRNACTDPMID:33387578
GanRat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of GAN mRNACTDPMID:22298810
GanRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:13171486480464Tetrachlorodibenzodioxin results in decreased expression of GAN mRNACTDPMID:21889950
GanRat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642,3,7,8-tetrachlorodibenzofuran results in decreased expression of GAN mRNACTDPMID:32109520
GanRat3,4-methylenedioxymethamphetamine decreases expressionISORGD:13171486480464N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of GAN mRNACTDPMID:20188158
GanRat4,4'-sulfonyldiphenol decreases expressionISORGD:13171486480464bisphenol S results in decreased expression of GAN mRNACTDPMID:39298647
GanRatacetamide decreases expressionEXP 6480464acetamide results in decreased expression of GAN mRNACTDPMID:31881176
GanRataflatoxin B1 increases expressionISORGD:13171486480464Aflatoxin B1 results in increased expression of GAN mRNACTDPMID:19770486
GanRataflatoxin B1 decreases expressionEXP 6480464Aflatoxin B1 results in decreased expression of GAN mRNACTDPMID:33354967
GanRataflatoxin B1 increases methylationISORGD:13171476480464Aflatoxin B1 results in increased methylation of GAN geneCTDPMID:27153756
GanRatarsenite(3-) multiple interactionsISORGD:13171476480464arsenite inhibits the reaction [G3BP1 protein binds to GAN mRNA]CTDPMID:32406909
GanRatBenoxacor decreases expressionISORGD:13171486480464benoxacor results in decreased expression of GAN mRNACTDPMID:34850242
GanRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of GAN mRNACTDPMID:25181051
GanRatbisphenol A decreases expressionISORGD:13171486480464bisphenol A results in decreased expression of GAN mRNACTDPMID:38074096
GanRatbisphenol A decreases methylationISORGD:13171486480464bisphenol A results in decreased methylation of GAN promoterCTDPMID:27312807
GanRatbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of GAN geneCTDPMID:28505145
GanRatbisphenol AF increases expressionEXP 6480464bisphenol AF results in increased expression of GAN mRNACTDPMID:27567155
GanRatbisphenol F increases expressionISORGD:13171486480464bisphenol F results in increased expression of GAN mRNACTDPMID:38685157
GanRatcarbon nanotube increases expressionISORGD:13171486480464Nanotubes, Carbon results in increased expression of GAN mRNACTDPMID:25620056

1 to 20 of 54 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GanRatcytoskeleton organization involved_inIEAInterPro:IPR0305791600115GO_REF:0000002InterProGO_REF:0000002
GanRatproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIBAFB:FBgn0037978|FB:FBgn0038475|FB:FBgn0040230|MGI:1919580|PANTHER:PTN001561260|UniProtKB:Q14145|UniProtKB:Q86V97|UniProtKB:Q8WVZ9|UniProtKB:Q9UH77|UniProtKB:Q9Y2M51600115GO_REF:0000033GO_CentralGO_REF:0000033
GanRatprotein ubiquitination involved_inISORGD:13171471624291 PMID:15983046RGDPMID:15983046

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GanRatCul3-RING ubiquitin ligase complex part_ofISORGD:13171471624291 PMID:15983046RGDPMID:15983046
GanRatCul3-RING ubiquitin ligase complex part_ofIBAFB:FBgn0037978|FB:FBgn0038475|FB:FBgn0040038|FB:FBgn0040230|MGI:1858732|MGI:1919580|MGI:1924363|PANTHER:PTN001561260|UniProtKB:O60662|UniProtKB:Q14145|UniProtKB:Q53G59|UniProtKB:Q6TFL4|UniProtKB:Q86V97|UniProtKB:Q8IXQ5|UniProtKB:Q8NFY9|UniProtKB:Q8WVZ9|UniProtKB:Q9H2C0|UniProtKB:Q9P2G9|UniProtKB:Q9UH77|UniProtKB:Q9UJP4|UniProtKB:Q9Y2M5|WB:WBGene000209521600115GO_REF:0000033GO_CentralGO_REF:0000033
GanRatcytoplasm located_inISORGD:13171471624291 PMID:19424503RGDPMID:19424503
GanRatcytoplasm is_active_inIBAMGI:1858732|MGI:1919580|MGI:1924363|MGI:2181067|MGI:2683854|MGI:3045316|PANTHER:PTN001561260|RGD:708444|UniProtKB:O60662|UniProtKB:Q13939|UniProtKB:Q14145|UniProtKB:Q53G59|UniProtKB:Q6TFL4|UniProtKB:Q86V97|UniProtKB:Q8IXQ5|UniProtKB:Q8IY47|UniProtKB:Q9H2C0|UniProtKB:Q9NR64|UniProtKB:Q9UH77|UniProtKB:Q9Y2M5|UniProtKB:Q9Y6Y01600115GO_REF:0000033GO_CentralGO_REF:0000033
GanRatcytoplasm located_inIEAARBA:ARBA000269711600115GO_REF:0000117UniProtGO_REF:0000117

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GanRatprotein binding enablesISORGD:13171471624291UniProtKB:O60260-5|UniProtKB:P22314|UniProtKB:P31947|UniProtKB:P40337-2|UniProtKB:P46821|UniProtKB:P62258|UniProtKB:Q5U300|UniProtKB:Q8IVD9|UniProtKB:Q99426 PMID:12147674, PMID:15778465, PMID:16227972, PMID:16303566, PMID:25036637, PMID:28514442, PMID:32814053, PMID:33961781, PMID:36931259RGDPMID:12147674|PMID:15778465|PMID:16227972|PMID:16303566|PMID:25036637|PMID:28514442|PMID:32814053|PMID:33961781|PMID:36931259
GanRatubiquitin-like ligase-substrate adaptor activity enablesIBAFB:FBgn0037978|FB:FBgn0038475|FB:FBgn0040230|PANTHER:PTN001561260|UniProtKB:O95198|UniProtKB:Q14145|UniProtKB:Q8IY47|UniProtKB:Q9UH771600115GO_REF:0000033GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:15983046   PMID:19424503  



Gan
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81962,116,600 - 62,173,879 (+)NCBIGRCr8
mRatBN7.21945,207,783 - 45,265,066 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1945,207,184 - 45,254,107 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1952,017,893 - 52,064,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01952,670,909 - 52,717,223 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01954,915,137 - 54,961,451 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01949,692,790 - 49,746,178 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1949,695,579 - 49,741,965 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01960,480,642 - 60,533,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41947,263,532 - 47,310,683 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11947,268,492 - 47,315,557 (+)NCBI
Celera1944,479,857 - 44,526,017 (+)NCBICelera
Cytogenetic Map19q12NCBI
GAN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381681,314,962 - 81,390,809 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1681,314,944 - 81,390,884 (+)EnsemblGRCh38hg38GRCh38
GRCh371681,348,567 - 81,424,414 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361679,906,076 - 79,971,441 (+)NCBINCBI36Build 36hg18NCBI36
Build 341679,906,075 - 79,971,441NCBI
Celera1665,645,867 - 65,711,100 (+)NCBICelera
Cytogenetic Map16q23.2NCBI
HuRef1667,103,386 - 67,168,596 (+)NCBIHuRef
CHM1_11682,759,876 - 82,825,083 (+)NCBICHM1_1
T2T-CHM13v2.01687,375,728 - 87,451,557 (+)NCBIT2T-CHM13v2.0
Gan
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398117,884,720 - 117,932,573 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8117,884,874 - 117,942,736 (+)EnsemblGRCm39 Ensembl
GRCm388117,157,981 - 117,205,834 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8117,158,135 - 117,215,997 (+)EnsemblGRCm38mm10GRCm38
MGSCv378119,682,035 - 119,729,086 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368120,044,112 - 120,091,163 (+)NCBIMGSCv36mm8
Celera8121,377,818 - 121,424,875 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map863.71NCBI
Gan
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555224,035,672 - 4,090,630 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555224,035,672 - 4,096,845 (+)NCBIChiLan1.0ChiLan1.0
GAN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21891,056,924 - 91,140,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11696,976,406 - 97,060,039 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01661,919,004 - 61,994,811 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11681,347,221 - 81,410,363 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1681,347,215 - 81,410,363 (+)Ensemblpanpan1.1panPan2
GAN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1570,518,667 - 70,579,398 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl570,530,396 - 70,579,567 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha570,488,907 - 70,528,607 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0570,823,382 - 70,884,349 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl570,827,374 - 70,884,517 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1570,766,100 - 70,826,821 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0570,601,294 - 70,662,010 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0571,079,113 - 71,139,854 (-)NCBIUU_Cfam_GSD_1.0
Gan
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934930,609,452 - 30,661,047 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647528,945,908 - 28,967,653 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647528,913,132 - 28,979,656 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl66,933,503 - 6,989,653 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.166,921,446 - 6,989,670 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.267,466,847 - 7,524,943 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GAN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1566,754,752 - 66,820,933 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl566,754,893 - 66,816,761 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660479,017,449 - 9,081,670 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gan
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247466,081,033 - 6,126,858 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247466,070,680 - 6,126,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gan
362 total Variants

Predicted Target Of
Summary Value
Count of predictions:501
Count of miRNA genes:261
Interacting mature miRNAs:332
Transcripts:ENSRNOT00000016963
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat

1 to 10 of 15 rows
AU047749  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21945,219,809 - 45,220,021 (+)MAPPERmRatBN7.2
Rnor_6.01949,707,511 - 49,707,722NCBIRnor6.0
Rnor_5.01960,494,570 - 60,494,781UniSTSRnor5.0
RGSC_v3.41947,275,479 - 47,275,690UniSTSRGSC3.4
Celera1944,491,791 - 44,492,002UniSTS
Cytogenetic Map19q12UniSTS
BQ193745  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21945,205,999 - 45,206,175 (+)MAPPERmRatBN7.2
Rnor_6.01949,693,715 - 49,693,890NCBIRnor6.0
Rnor_5.01960,480,774 - 60,480,949UniSTSRnor5.0
RGSC_v3.41947,261,668 - 47,261,843UniSTSRGSC3.4
Celera1944,477,993 - 44,478,168UniSTS
RH 3.4 Map19631.7UniSTS
Cytogenetic Map19q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000016963   ⟹   ENSRNOP00000016963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1945,207,184 - 45,254,107 (+)Ensembl
Rnor_6.0 Ensembl1949,695,579 - 49,741,965 (+)Ensembl
RefSeq Acc Id: NM_001414939   ⟹   NP_001401868
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81962,116,600 - 62,173,879 (+)NCBI
mRatBN7.21945,207,783 - 45,265,066 (+)NCBI
RefSeq Acc Id: XM_039097773   ⟹   XP_038953701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81962,147,610 - 62,173,879 (+)NCBI
mRatBN7.21945,238,804 - 45,258,831 (+)NCBI
RefSeq Acc Id: XM_039097774   ⟹   XP_038953702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81962,116,797 - 62,173,879 (+)NCBI
mRatBN7.21945,207,982 - 45,258,831 (+)NCBI
Protein RefSeqs NP_001401868 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953701 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953702 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL92649 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016963.6
  ENSRNOP00000112441
Ensembl Acc Id: ENSRNOP00000016963   ⟸   ENSRNOT00000016963
RefSeq Acc Id: XP_038953702   ⟸   XM_039097774
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953701   ⟸   XM_039097773
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001401868   ⟸   NM_001414939
- UniProtKB: A6IZH1 (UniProtKB/TrEMBL),   D3ZRI9 (UniProtKB/TrEMBL)
BTB

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZRI9-F1-model_v2 AlphaFold D3ZRI9 1-603 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701171
Promoter ID:EPDNEW_R11694
Type:single initiation site
Name:Gan_1
Description:gigaxonin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01949,695,498 - 49,695,558EPDNEW


1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-5554 BioCyc
Ensembl Genes ENSRNOG00000012671 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016963.6 UniProtKB/TrEMBL
  ENSRNOT00000172870 ENTREZGENE
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
  Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB/POZ-like UniProtKB/TrEMBL
  BTB/POZ_fold UniProtKB/TrEMBL
  Kelch-like_gigaxonin UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  KLHL16 UniProtKB/TrEMBL
  KLHL16_BTB_POZ UniProtKB/TrEMBL
NCBI Gene 307893 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/TrEMBL
  KELCH-LIKE PROTEIN 31 UniProtKB/TrEMBL
  LD33804P UniProtKB/TrEMBL
  PTHR24412:SF232 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PhenoGen Gan PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012671 RatGTEx
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP BTB/POZ_fold UniProtKB/TrEMBL
  SSF117281 UniProtKB/TrEMBL
UniProt A6IZH1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZRI9 ENTREZGENE, UniProtKB/TrEMBL
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Gan  gigaxonin  Gan  giant axonal neuropathy   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Gan  giant axonal neuropathy   Gan_predicted  giant axonal neuropathy (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Gan_predicted  giant axonal neuropathy (predicted)      Symbol and Name status set to approved 70820 APPROVED