GAN (gigaxonin) - Rat Genome Database

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Advanced Search (OLGA)
Gene: GAN (gigaxonin) Pan paniscus
Analyze
Symbol: GAN
Name: gigaxonin
RGD ID: 11970428
Description: INVOLVED IN cytoskeleton organization (inferred); protein ubiquitination (inferred); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); developmental and epileptic encephalopathy 1 (ortholog); familial cold autoinflammatory syndrome 3 (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21891,056,924 - 91,140,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11696,976,406 - 97,060,039 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01661,919,004 - 61,994,811 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11681,347,221 - 81,410,363 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1681,347,215 - 81,410,363 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
GAN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21891,056,924 - 91,140,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11696,976,406 - 97,060,039 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01661,919,004 - 61,994,811 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11681,347,221 - 81,410,363 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1681,347,215 - 81,410,363 (+)Ensemblpanpan1.1panPan2
GAN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381681,314,962 - 81,390,809 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1681,314,944 - 81,390,884 (+)EnsemblGRCh38hg38GRCh38
GRCh371681,348,567 - 81,424,414 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361679,906,076 - 79,971,441 (+)NCBINCBI36Build 36hg18NCBI36
Build 341679,906,075 - 79,971,441NCBI
Celera1665,645,867 - 65,711,100 (+)NCBICelera
Cytogenetic Map16q23.2NCBI
HuRef1667,103,386 - 67,168,596 (+)NCBIHuRef
CHM1_11682,759,876 - 82,825,083 (+)NCBICHM1_1
T2T-CHM13v2.01687,375,728 - 87,451,557 (+)NCBIT2T-CHM13v2.0
Gan
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398117,884,720 - 117,932,573 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8117,884,874 - 117,942,736 (+)EnsemblGRCm39 Ensembl
GRCm388117,157,981 - 117,205,834 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8117,158,135 - 117,215,997 (+)EnsemblGRCm38mm10GRCm38
MGSCv378119,682,035 - 119,729,086 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368120,044,112 - 120,091,163 (+)NCBIMGSCv36mm8
Celera8121,377,818 - 121,424,875 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map863.71NCBI
Gan
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81962,116,600 - 62,173,879 (+)NCBIGRCr8
mRatBN7.21945,207,783 - 45,265,066 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1945,207,184 - 45,254,107 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1952,017,893 - 52,064,198 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01952,670,909 - 52,717,223 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01954,915,137 - 54,961,451 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01949,692,790 - 49,746,178 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1949,695,579 - 49,741,965 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01960,480,642 - 60,533,157 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41947,263,532 - 47,310,683 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11947,268,492 - 47,315,557 (+)NCBI
Celera1944,479,857 - 44,526,017 (+)NCBICelera
Cytogenetic Map19q12NCBI
Gan
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555224,035,672 - 4,090,630 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555224,035,672 - 4,096,845 (+)NCBIChiLan1.0ChiLan1.0
GAN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1570,518,667 - 70,579,398 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl570,530,396 - 70,579,567 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha570,488,907 - 70,528,607 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0570,823,382 - 70,884,349 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl570,827,374 - 70,884,517 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1570,766,100 - 70,826,821 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0570,601,294 - 70,662,010 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0571,079,113 - 71,139,854 (-)NCBIUU_Cfam_GSD_1.0
Gan
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934930,609,452 - 30,661,047 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647528,945,908 - 28,967,653 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647528,913,132 - 28,979,656 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GAN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl66,933,503 - 6,989,653 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.166,921,446 - 6,989,670 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.267,466,847 - 7,524,943 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GAN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1566,754,752 - 66,820,933 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl566,754,893 - 66,816,761 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660479,017,449 - 9,081,670 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gan
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247466,081,033 - 6,126,858 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247466,070,680 - 6,126,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000057614   ⟹   ENSPPAP00000034730
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1681,347,215 - 81,407,794 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057621   ⟹   ENSPPAP00000034737
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1681,347,221 - 81,410,363 (+)Ensembl
RefSeq Acc Id: XM_003820889   ⟹   XP_003820937
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21891,056,924 - 91,140,629 (+)NCBI
NHGRI_mPanPan11696,976,406 - 97,060,039 (+)NCBI
Mhudiblu_PPA_v01661,919,004 - 61,994,811 (+)NCBI
PanPan1.11681,347,221 - 81,410,363 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034940792   ⟹   XP_034796683
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21891,066,661 - 91,140,629 (+)NCBI
NHGRI_mPanPan11696,986,134 - 97,060,039 (+)NCBI
Mhudiblu_PPA_v01661,920,724 - 61,988,233 (+)NCBI
RefSeq Acc Id: XR_008621540
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21891,056,924 - 91,140,629 (+)NCBI
NHGRI_mPanPan11696,976,406 - 97,060,039 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003820937 (Get FASTA)   NCBI Sequence Viewer  
  XP_034796683 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034730.1
  ENSPPAP00000034737.1
RefSeq Acc Id: XP_003820937   ⟸   XM_003820889
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C1S2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034796683   ⟸   XM_034940792
- Peptide Label: isoform X2
Ensembl Acc Id: ENSPPAP00000034730   ⟸   ENSPPAT00000057614
Ensembl Acc Id: ENSPPAP00000034737   ⟸   ENSPPAT00000057621
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040205 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057614.1 UniProtKB/TrEMBL
  ENSPPAT00000057621.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  KLHL16 UniProtKB/TrEMBL
  KLHL16_BTB_POZ UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
KEGG Report pps:100987235 UniProtKB/TrEMBL
NCBI Gene GAN ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/TrEMBL
  PTHR24412:SF232 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A2R9BYJ1_PANPA UniProtKB/TrEMBL
  A0A2R9C1S2 ENTREZGENE, UniProtKB/TrEMBL