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Gene: Zfp422 (zinc finger protein 422) Rattus norvegicus

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Symbol:

Zfp422

Name:

zinc finger protein 422

RGD ID:

620229

Description:

Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human ZNF22 (zinc finger protein 22); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Kox15; Krox-25; krueppel-type zinc finger protein Krox-25; LOC360389; MGC105332; zinc finger protein 22; zinc finger protein 22 (KOX 15); zinc finger protein Krox-25; Znf22

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNF22 (zinc finger protein 22)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Zfp422 (zinc finger protein 422)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znf22 (zinc finger protein 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNF22 (zinc finger protein 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNF22 (zinc finger protein 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Znf22 (zinc finger protein 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNF22 (zinc finger protein 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNF22 (zinc finger protein 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znf22 (zinc finger protein 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Znf22 (zinc finger protein 22)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZNF671 (zinc finger protein 671)	HGNC	Panther
Alliance orthologs ³
Homo sapiens (human):	ZNF22 (zinc finger protein 22)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ZNF22 (zinc finger protein 22)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zfp422 (zinc finger protein 422)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zfp422 (zinc finger protein 422)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	151,558,254 - 151,565,730 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	151,556,738 - 151,566,152 (-)	Ensembl				GRCr8
mRatBN7.2	4	149,885,805 - 149,893,287 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	149,885,600 - 149,893,257 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	156,127,719 - 156,131,903 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	151,911,761 - 151,915,945 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	150,534,653 - 150,538,837 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	148,757,362 - 148,761,594 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	148,757,363 - 148,761,547 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	214,696,097 - 214,703,529 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	152,975,181 - 152,979,366 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	138,761,375 - 138,765,560 (-)	NCBI		Celera
RGSC_v3.1	4	153,220,022 - 153,222,083 (-)	NCBI
Cytogenetic Map	4	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,6-dinitrotoluene (EXP)

2-butoxyethanol (ISO)

2-methylcholine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

azoxystrobin (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

butan-1-ol (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chlorpyrifos (EXP)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dextran sulfate (ISO)

Dibutyl phosphate (ISO)

dimethyl sulfoxide (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

Evodiamine (ISO)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

glyphosate (EXP)

gold atom (ISO)

gold(0) (ISO)

imidacloprid (EXP)

indometacin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (EXP)

methimazole (EXP)

methyl methanesulfonate (ISO)

mifepristone (ISO)

nickel sulfate (ISO)

nitric oxide (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

resveratrol (ISO)

S-butyl-DL-homocysteine (S,R)-sulfoximine (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

T-2 toxin (ISO)

thiabendazole (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

odontogenesis (NAS)

regulation of DNA-templated transcription (NAS)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleoplasm (IEA,ISO)

nucleus (IDA,IEA)

Molecular Function

DNA binding (IEA,ISO,ISS)

DNA-binding transcription factor activity (IBA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Molecular cloning, chromosomal mapping, and characteristic expression in tooth organ of rat and mouse Krox-25.	Lee SK, etal., Genomics 2004 Feb;83(2):243-53.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Information Derived from GenBank Report	RGD, Sept. 2003
9.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:12952191	PMID:15489334

Genomics

Comparative Map Data

Zfp422
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	151,558,254 - 151,565,730 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	151,556,738 - 151,566,152 (-)	Ensembl				GRCr8
mRatBN7.2	4	149,885,805 - 149,893,287 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	149,885,600 - 149,893,257 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	156,127,719 - 156,131,903 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	151,911,761 - 151,915,945 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	150,534,653 - 150,538,837 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	148,757,362 - 148,761,594 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	148,757,363 - 148,761,547 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	4	214,696,097 - 214,703,529 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	152,975,181 - 152,979,366 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	138,761,375 - 138,765,560 (-)	NCBI		Celera
RGSC_v3.1	4	153,220,022 - 153,222,083 (-)	NCBI
Cytogenetic Map	4	q42	NCBI

ZNF22
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	45,000,923 - 45,005,326 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	45,000,293 - 45,005,329 (+)	Ensembl			hg38	GRCh38
GRCh37	10	45,496,371 - 45,500,774 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	44,815,928 - 44,820,780 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	44,815,927 - 44,820,779	NCBI
Celera	10	41,499,447 - 41,503,956 (+)	NCBI		Celera
Cytogenetic Map	10	q11.21	NCBI
HuRef	10	42,021,639 - 42,026,148 (+)	NCBI		HuRef
CHM1_1	10	45,535,250 - 45,539,759 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	45,881,879 - 45,886,287 (+)	NCBI		T2T-CHM13v2.0

Zfp422
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	116,600,977 - 116,605,960 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	116,600,977 - 116,605,960 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	116,624,016 - 116,628,999 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	116,624,016 - 116,628,999 (-)	Ensembl			mm10	GRCm38
MGSCv37	6	116,574,034 - 116,578,995 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	116,589,635 - 116,594,596 (-)	NCBI		MGSCv36	mm8
Celera	6	118,464,009 - 118,468,970 (-)	NCBI		Celera
Cytogenetic Map	6	E3	NCBI
cM Map	6	53.83	NCBI

Znf22
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955546	2,308,714 - 2,313,334 (+)	NCBI	ChiLan1.0	ChiLan1.0

ZNF22
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	57,732,409 - 57,740,037 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	57,740,749 - 57,745,366 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	41,995,117 - 41,999,954 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	45,174,724 - 45,179,566 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	45,177,605 - 45,178,279 (+)	Ensembl			panPan2	panpan1.1

ZNF22
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	2,442,533 - 2,446,900 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	2,443,817 - 2,444,494 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	2,677,916 - 2,682,377 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	2,621,396 - 2,625,769 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	2,616,873 - 2,625,770 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	2,419,957 - 2,424,336 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	2,457,201 - 2,461,679 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	2,588,391 - 2,592,850 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Znf22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	82,015,950 - 82,020,323 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936617	4,763,617 - 4,767,974 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936617	4,763,374 - 4,768,035 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF22
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	91,085,561 - 91,094,406 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	91,092,440 - 91,096,888 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	99,555,640 - 99,560,085 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNF22
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	40,625,251 - 40,630,492 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	40,628,570 - 40,629,244 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666056	45,773,918 - 45,779,096 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znf22
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624966	3,088 - 18,549 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Znf22
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	29,978,037 - 29,982,200 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Zfp422
49 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	185
Count of miRNA genes:	130
Interacting mature miRNAs:	160
Transcripts:	ENSRNOT00000018050
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	146370897	184426481	Rat
2302049	Pia32	Pristane induced arthritis QTL 32	5.1	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)	4	107346299	152346299	Rat
724558	Plsm2	Polydactyly-luxate syndrome (PLS) morphotypes QTL 2		0.0003	hindlimb integrity trait (VT:0010563)	hind foot phalanges count (CMO:0001949)	4	134095016	179095016	Rat
1582237	Kidm34	Kidney mass QTL 34	4	0.0001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	4	149763204	169799698	Rat
61446	Coreg2	Compensatory renal growth QTL 2	3.5		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	4	150095743	159267220	Rat
1300116	Hrtrt5	Heart rate QTL 5	3.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	117737142	152833657	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	146370897	184426481	Rat
1358364	Sradr4	Stress Responsive Adrenal Weight QTL 4	4.92		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	131384565	176384565	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
6478763	Anxrr46	Anxiety related response QTL 46		0.07428	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	112427331	157427331	Rat
6478760	Anxrr45	Anxiety related response QTL 45		0.06717	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	112427331	157427331	Rat
61451	Ciaa4	CIA Autoantibody QTL 4	3.1		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	4	123870974	168870974	Rat
1331802	Srn5	Serum renin concentration QTL 5	3.045		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	4	117559384	162559384	Rat
1331738	Bp209	Blood pressure QTL 209	2.979		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	140059299	181024663	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
1298524	Oia8	Oil induced arthritis QTL 8			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
7207480	Bss105	Bone structure and strength QTL 105	8.1		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	4	111383604	156383604	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	94638356	168870820	Rat
737821	Hcar9	Hepatocarcinoma resistance QTL 9	3.7		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	106848959	168870974	Rat
731165	Uae21	Urinary albumin excretion QTL 21	2.4	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	108206096	153206096	Rat
7411558	Bw133	Body weight QTL 133	13.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	127263297	172263297	Rat
6478778	Anxrr51	Anxiety related response QTL 51		0.25384	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	126334185	171334185	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	147299608	184426481	Rat
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
631511	Pia7	Pristane induced arthritis QTL 7	4.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	123870974	168870974	Rat
1549832	Bss3	Bone structure and strength QTL 3	11		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	4	111383604	156383604	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	82944895	154403548	Rat
634347	Hcar8	Hepatocarcinoma resistance QTL 8	5.8		liver integrity trait (VT:0010547)	liver tumorous lesion area to total liver area ratio (CMO:0001075)	4	124700988	169700988	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	100752691	179366077	Rat
1581566	Eae21	Experimental allergic encephalomyelitis QTL 21	6.2		body mass (VT:0001259)	maximum body weight loss to initial body weight ratio (CMO:0001400)	4	137447185	182447185	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	45429709	157555683	Rat
1578674	Bmd12	Bone mineral density QTL 12	3.8		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	4	137430611	182430611	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	86709649	168870974	Rat
61422	Cia13	Collagen induced arthritis QTL 13	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	134199006	168870974	Rat
634342	Cia24	Collagen induced arthritis QTL 24	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	148121375	176967367	Rat
737978	Pia23	Pristane induced arthritis QTL 23	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	123870974	168870974	Rat
61362	Oia2	Oil induced arthritis QTL 2		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	65495851	159259805	Rat
12798519	Anxrr54	Anxiety related response QTL 54	2.54	0.05	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	116184844	161184844	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
12798525	Anxrr57	Anxiety related response QTL 57	3.21	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	148834094	168870974	Rat

Markers in Region

RH136766

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	149,886,151 - 149,886,255 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	148,757,708 - 148,757,811	NCBI	Rnor6.0
Rnor_5.0	4	214,696,443 - 214,696,546	UniSTS	Rnor5.0
RGSC_v3.4	4	152,975,527 - 152,975,630	UniSTS	RGSC3.4
Celera	4	138,761,721 - 138,761,824	UniSTS
RH 3.4 Map	4	950.6	UniSTS
RH 3.4 Map	4	967.3	UniSTS
Cytogenetic Map	4	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237187	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006237190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039107733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF281635	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY724498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC090354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018050 ⟹ ENSRNOP00000018050

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	151,556,738 - 151,566,152 (-)	Ensembl
mRatBN7.2 Ensembl	4	149,885,806 - 149,893,257 (-)	Ensembl
Rnor_6.0 Ensembl	4	148,757,363 - 148,761,547 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097804 ⟹ ENSRNOP00000076367

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	151,556,738 - 151,566,152 (-)	Ensembl
mRatBN7.2 Ensembl	4	149,885,600 - 149,890,233 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105818 ⟹ ENSRNOP00000085999

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	149,885,806 - 149,889,421 (-)	Ensembl

RefSeq Acc Id:

NM_001012745 ⟹ NP_001012763

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	151,558,254 - 151,562,439 (-)	NCBI
mRatBN7.2	4	149,885,806 - 149,889,994 (-)	NCBI
Rnor_6.0	4	148,757,362 - 148,761,547 (-)	NCBI
Rnor_5.0	4	214,696,097 - 214,703,529 (-)	NCBI
RGSC_v3.4	4	152,975,181 - 152,979,366 (-)	RGD
Celera	4	138,761,375 - 138,765,560 (-)	RGD

Sequence:

show sequence

CTTGGCCTTGCGGTCCGTGGGTCTGCCTTCTGAGTGGTAAGCGAGGAATACAAAAGGACCGCCT
AAAGAAGCCGCAGGACTCGGTGGGCTGGGCTGGGGACCATAGAGGGTCTCTCCGCCTCTTCCTA
GAGCGGCCCGCAGCTCCGCTAGGAGCTCGCACTTCCGGCGGGCGAGGCGGGAGGCGAGCACCGT
GGCGGCCTGCACGAAAATTCTGAGTTGCGTTACTCTAGGATATGAGACCTTAGTTCAGAAGTTC
AGAAGACAGTACAATCTCTTGTCAGTACATTTGGCTGCTCACCATGAGGTTAGGAAAGCCTAAG
GGGGGTATTTCTCGAAGTGCAAGCCAAGGAAAAACCTATGAGAGCAAGCGCAAGACAGCCCGCC
AGCGACAGAAATGGGGGGTGGCCATTCGCTTCGACTCAGGGTTAAGTAGACGGAGAAGAAACGT
GGATGAGAAGCCTTACAAATGTACTAAATGTTCTAAGAGTTTCAGTCAGAGCTCCACTCTTTTT
CAGCACAAGAAGATCCACACTGGGAAGAAATCCCATAAATGTGCCGATTGTGGGAAAAGTTTCT
TTCAGAGTTCTAACCTCATTCAGCATCGGCGGATCCACACGGGGGAAAAGCCCTATAAGTGCGA
CGAGTGTGGAGAGAGATTTAAACAGAGCTCCAACCTTATCCAGCACCAGAGGATTCACACCGGG
GAGAAGCCCTATTGCTGCGATGAGTGTGGCCGGTGCTTTAGCCAGAGTTCCCACCTCATTCAGC
ACCAGAGAACCCACACCGGAGAAAAGCCCTACCAGTGCGAGGAGTGTGACAAGTGCTTCAGCCA
GAGCTCCCACCTGAGGCAGCACATGAAGGTGCACAAAGAAAAGAAGTCACATAAAAGGGGTAAA
AATGCCAGGGCGAAAACTCACCCGGTGTCCTGGAAACGTGGTAAAGGAAGGAAGGCAGTGGCTG
GGCTCCGCCAGGTAAAGGGAGCCGCTTCGGGCCTTTTCAAAAAGAAGAAGTGAATCTCGTAGCG
GTGAAAGCCTCTCCCAAGAGGGAGGACACTTTACAGTAGATAGAGCACTTAGATACTGGTCCTC
CCTAGCATGGAGATGTCAGGAGTTTCATGACAATGGGCTGAAACTCTGAGTCTAGCCATCCTCA
TTTCCTTTCAGAATAAATAAGTAAATTTATGTGACATGGAGCAGAAAACTGAAAAAAAAGTTTG
GTAAGAATTTAACATCCTTGGCCTCAGTTGAAATTTCTTCCCTACGTTTTGATAAAAAGCGTCA
TGTTTTCATGATTCACTGGTGTGCCAATGATTACTCTTGGTTTTAGGAATTTCTGTATACAAAA
TCATTAAAGAGAAGGAATGAGTTTTCAAGTTCTAGGACCGACTATATTTTTAATGTTTTGTAGT
TTTTTTTAACCATTAGTATCAGCATTGATTCAGTATTTGACATAATAAAATGCATTCAAGTTCA
TAGATTTTTGTATTTTTTATTAGCGTATATTGTATGAAGTAATGAGTTCGTTTTCTTTAATGTG
TACGATGTATCTGTATGATGTGCTTTGATTATATCCATTGCTCTTACCCTCACCTCCACCTCCT
GGTTCTCTTCTTCCTCCCAGAGAGTTCCCTTCCCACTTGAATTGTTGACCCTGGATTCTGTGAA
TGACAGAAATTGTCTTTGGTTATTTTTCCACATCTGCTTTACTGTGTTTACTGTAATGTTCTCC
AGTTCTATCCATTTTTCGCCAAACAACAGGATTTTGGCTTCTTTTTTTTTTTTTTTTAACTAAT
AAGTTTGTCATAGTGTCTGATGCTTTAATGAAGGGGTGAAAAGGTCTCCATGTGGCTTTTCTTT
TGTTTGTTTTTTGTTTACCATATTCTTAGAGATTTCAAAGAATCCAAAGTGAGAAACTGCAGAC
CTCCTCCTAAGACCATTACTTGCGATGCTGATGCCCTGCCTCTTGCTTTCTTGAAATGGGAATG
GTTTATGTTGAATCATGCCAGTGGCCTCTTGGCGTTCCTTTGTTCTCTTGCAAACAGGGCCTGC
ATGAATAAACTATGTTACCAAGAAAGCCTGACTTACTTCTGGCTAAAGAACTACAGTGTCATAG
ACTGAGCTTTGACTGCCGCTGACTGAGACAGATGTGTGTCTACAAGTTCCTGGAGCCCTGTTAG
AACTTAACTGTTCTTTACTTTTTAGCAGTTGTTTAAGAAGACTAGCGGACATCCTTTTTCGAAT
GCTAAGCCTGAGTTCCTAGTTAACCCTTAGTTCAAGTTTTTGTTTATTGAATGCTAATGTTTTC
TGATTTTTATAATCTCACTTCTTCCTGTATTAATGACAATTATCCTCAAAATAAAGATTGAGAT
ATTTTTGCGTAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006237187 ⟹ XP_006237249

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	151,558,254 - 151,562,204 (-)	NCBI
mRatBN7.2	4	149,885,805 - 149,889,833 (-)	NCBI
Rnor_6.0	4	148,757,362 - 148,761,482 (-)	NCBI
Rnor_5.0	4	214,696,097 - 214,703,529 (-)	NCBI

Sequence:

show sequence

AAGAAGCCGCAGGACTCGGTGGGCTGGGCTGGGGACCATAGAGGGTCTCTCCGCCTCTTCCTAG
AGCGGCCCGCAGCTCCGCTAGGAGCTCGCACTTCCGGCGGGCGAGGCGGGAGGCGAGCACCGTG
GCGGCCTGCACGGTGAGTGCGCCAGGCCTGCGGGTCGGCCTGGACCGGTGTGGGGTCGGGCTGC
GGCGCTTCACGGAGCCGGGCGGGCGGCCTCGGCCTGGGGTCAGTCTCGGCCTGAGCGCCTCGGC
TCGCTGCGGAGAAAGACTCCATTGTACGACTGCGTAGGCTGCACCGGGCCATTAAAATTCTGAG
TTGCGTTACTCTAGGATATGAGACCTTAGTTCAGAAGTTCAGAAGACAGTACAATCTCTTGTCA
GTACATTTGGCTGCTCACCATGAGGTTAGGAAAGCCTAAGGGGGGTATTTCTCGAAGTGCAAGC
CAAGGAAAAACCTATGAGAGCAAGCGCAAGACAGCCCGCCAGCGACAGAAATGGGGGGTGGCCA
TTCGCTTCGACTCAGGGTTAAGTAGACGGAGAAGAAACGTGGATGAGAAGCCTTACAAATGTAC
TAAATGTTCTAAGAGTTTCAGTCAGAGCTCCACTCTTTTTCAGCACAAGAAGATCCACACTGGG
AAGAAATCCCATAAATGTGCCGATTGTGGGAAAAGTTTCTTTCAGAGTTCTAACCTCATTCAGC
ATCGGCGGATCCACACGGGGGAAAAGCCCTATAAGTGCGACGAGTGTGGAGAGAGATTTAAACA
GAGCTCCAACCTTATCCAGCACCAGAGGATTCACACCGGGGAGAAGCCCTATTGCTGCGATGAG
TGTGGCCGGTGCTTTAGCCAGAGTTCCCACCTCATTCAGCACCAGAGAACCCACACCGGAGAAA
AGCCCTACCAGTGCGAGGAGTGTGACAAGTGCTTCAGCCAGAGCTCCCACCTGAGGCAGCACAT
GAAGGTGCACAAAGAAAAGAAGTCACATAAAAGGGGTAAAAATGCCAGGGCGAAAACTCACCCG
GTGTCCTGGAAACGTGGTAAAGGAAGGAAGGCAGTGGCTGGGCTCCGCCAGGTAAAGGGAGCCG
CTTCGGGCCTTTTCAAAAAGAAGAAGTGAATCTCGTAGCGGTGAAAGCCTCTCCCAAGAGGGAG
GACACTTTACAGTAGATAGAGCACTTAGATACTGGTCCTCCCTAGCATGGAGATGTCAGGAGTT
TCATGACAATGGGCTGAAACTCTGAGTCTAGCCATCCTCATTTCCTTTCAGAATAAATAAGTAA
ATTTATGTGACATGGAGCAGAAAACTGAAAAAAAAGTTTGGTAAGAATTTAACATCCTTGGCCT
CAGTTGAAATTTCTTCCCTACGTTTTGATAAAAAGCGTCATGTTTTCATGATTCACTGGTGTGC
CAATGATTACTCTTGGTTTTAGGAATTTCTGTATACAAAATCATTAAAGAGAAGGAATGAGTTT
TCAAGTTCTAGGACCGACTATATTTTTAATGTTTTGTAGTTTTTTTTAACCATTAGTATCAGCA
TTGATTCAGTATTTGACATAATAAAATGCATTCAAGTTCATAGATTTTTGTATTTTTTATTAGC
GTATATTGTATGAAGTAATGAGTTCGTTTTCTTTAATGTGTACGATGTATCTGTATGATGTGCT
TTGATTATATCCATTGCTCTTACCCTCACCTCCACCTCCTGGTTCTCTTCTTCCTCCCAGAGAG
TTCCCTTCCCACTTGAATTGTTGACCCTGGATTCTGTGAATGACAGAAATTGTCTTTGGTTATT
TTTCCACATCTGCTTTACTGTGTTTACTGTAATGTTCTCCAGTTCTATCCATTTTTCGCCAAAC
AACAGGATTTTGGCTTCTTTTTTTTTTTTTTTTAACTAATAAGTTTGTCATAGTGTCTGATGCT
TTAATGAAGGGGTGAAAAGGTCTCCATGTGGCTTTTCTTTTGTTTGTTTTTTGTTTACCATATT
CTTAGAGATTTCAAAGAATCCAAAGTGAGAAACTGCAGACCTCCTCCTAAGACCATTACTTGCG
ATGCTGATGCCCTGCCTCTTGCTTTCTTGAAATGGGAATGGTTTATGTTGAATCATGCCAGTGG
CCTCTTGGCGTTCCTTTGTTCTCTTGCAAACAGGGCCTGCATGAATAAACTATGTTACCAAGAA
AGCCTGACTTACTTCTGGCTAAAGAACTACAGTGTCATAGACTGAGCTTTGACTGCCGCTGACT
GAGACAGATGTGTGTCTACAAGTTCCTGGAGCCCTGTTAGAACTTAACTGTTCTTTACTTTTTA
GCAGTTGTTTAAGAAGACTAGCGGACATCCTTTTTCGAATGCTAAGCCTGAGTTCCTAGTTAAC
CCTTAGTTCAAGTTTTTGTTTATTGAATGCTAATGTTTTCTGATTTTTATAATCTCACTTCTTC
CTGTATTAATGACAATTATCCTCAAAATAAAGATTGAGATATTTTTGCGTA

hide sequence

RefSeq Acc Id:

XM_006237189 ⟹ XP_006237251

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	151,558,254 - 151,562,466 (-)	NCBI
mRatBN7.2	4	149,885,805 - 149,889,978 (-)	NCBI
Rnor_6.0	4	148,757,362 - 148,761,594 (-)	NCBI
Rnor_5.0	4	214,696,097 - 214,703,529 (-)	NCBI

Sequence:

show sequence

AAGGCCAATTTCTGTGTAGCTCGACCGGAATAGAAAGAGAGCGGGTACTTGGCCTTGCGGTCCG
TGGGTCTGCCTTCTGAGTGAAAATTCTGAGTTGCGTTACTCTAGGATATGAGACCTTAGTTCAG
AAGTTCAGAAGACAGTACAATCTCTTGTCAGTACATTTGGCTGCTCACCATGAGGTTAGGAAAG
CCTAAGGGGGGTATTTCTCGAAGTGCAAGCCAAGGAAAAACCTATGAGAGCAAGCGCAAGACAG
CCCGCCAGCGACAGAAATGGGGGGTGGCCATTCGCTTCGACTCAGGGTTAAGTAGACGGAGAAG
AAACGTGGATGAGAAGCCTTACAAATGTACTAAATGTTCTAAGAGTTTCAGTCAGAGCTCCACT
CTTTTTCAGCACAAGAAGATCCACACTGGGAAGAAATCCCATAAATGTGCCGATTGTGGGAAAA
GTTTCTTTCAGAGTTCTAACCTCATTCAGCATCGGCGGATCCACACGGGGGAAAAGCCCTATAA
GTGCGACGAGTGTGGAGAGAGATTTAAACAGAGCTCCAACCTTATCCAGCACCAGAGGATTCAC
ACCGGGGAGAAGCCCTATTGCTGCGATGAGTGTGGCCGGTGCTTTAGCCAGAGTTCCCACCTCA
TTCAGCACCAGAGAACCCACACCGGAGAAAAGCCCTACCAGTGCGAGGAGTGTGACAAGTGCTT
CAGCCAGAGCTCCCACCTGAGGCAGCACATGAAGGTGCACAAAGAAAAGAAGTCACATAAAAGG
GGTAAAAATGCCAGGGCGAAAACTCACCCGGTGTCCTGGAAACGTGGTAAAGGAAGGAAGGCAG
TGGCTGGGCTCCGCCAGGTAAAGGGAGCCGCTTCGGGCCTTTTCAAAAAGAAGAAGTGAATCTC
GTAGCGGTGAAAGCCTCTCCCAAGAGGGAGGACACTTTACAGTAGATAGAGCACTTAGATACTG
GTCCTCCCTAGCATGGAGATGTCAGGAGTTTCATGACAATGGGCTGAAACTCTGAGTCTAGCCA
TCCTCATTTCCTTTCAGAATAAATAAGTAAATTTATGTGACATGGAGCAGAAAACTGAAAAAAA
AGTTTGGTAAGAATTTAACATCCTTGGCCTCAGTTGAAATTTCTTCCCTACGTTTTGATAAAAA
GCGTCATGTTTTCATGATTCACTGGTGTGCCAATGATTACTCTTGGTTTTAGGAATTTCTGTAT
ACAAAATCATTAAAGAGAAGGAATGAGTTTTCAAGTTCTAGGACCGACTATATTTTTAATGTTT
TGTAGTTTTTTTTAACCATTAGTATCAGCATTGATTCAGTATTTGACATAATAAAATGCATTCA
AGTTCATAGATTTTTGTATTTTTTATTAGCGTATATTGTATGAAGTAATGAGTTCGTTTTCTTT
AATGTGTACGATGTATCTGTATGATGTGCTTTGATTATATCCATTGCTCTTACCCTCACCTCCA
CCTCCTGGTTCTCTTCTTCCTCCCAGAGAGTTCCCTTCCCACTTGAATTGTTGACCCTGGATTC
TGTGAATGACAGAAATTGTCTTTGGTTATTTTTCCACATCTGCTTTACTGTGTTTACTGTAATG
TTCTCCAGTTCTATCCATTTTTCGCCAAACAACAGGATTTTGGCTTCTTTTTTTTTTTTTTTTA
ACTAATAAGTTTGTCATAGTGTCTGATGCTTTAATGAAGGGGTGAAAAGGTCTCCATGTGGCTT
TTCTTTTGTTTGTTTTTTGTTTACCATATTCTTAGAGATTTCAAAGAATCCAAAGTGAGAAACT
GCAGACCTCCTCCTAAGACCATTACTTGCGATGCTGATGCCCTGCCTCTTGCTTTCTTGAAATG
GGAATGGTTTATGTTGAATCATGCCAGTGGCCTCTTGGCGTTCCTTTGTTCTCTTGCAAACAGG
GCCTGCATGAATAAACTATGTTACCAAGAAAGCCTGACTTACTTCTGGCTAAAGAACTACAGTG
TCATAGACTGAGCTTTGACTGCCGCTGACTGAGACAGATGTGTGTCTACAAGTTCCTGGAGCCC
TGTTAGAACTTAACTGTTCTTTACTTTTTAGCAGTTGTTTAAGAAGACTAGCGGACATCCTTTT
TCGAATGCTAAGCCTGAGTTCCTAGTTAACCCTTAGTTCAAGTTTTTGTTTATTGAATGCTAAT
GTTTTCTGATTTTTATAATCTCACTTCTTCCTGTATTAATGACAATTATCCTCAAAATAAAGAT
TGAGATATTTTTGCGTA

hide sequence

RefSeq Acc Id:

XM_006237190 ⟹ XP_006237252

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	151,558,254 - 151,562,158 (-)	NCBI
mRatBN7.2	4	149,885,805 - 149,889,782 (-)	NCBI
Rnor_6.0	4	148,757,362 - 148,761,191 (-)	NCBI
Rnor_5.0	4	214,696,097 - 214,703,529 (-)	NCBI

Sequence:

show sequence

AGGCTGCACCGGGCCATTGTGAGCGACTTGGAGGGAGCCGGGGAGGCTTTGTTGCTCTGAAAAT
TCTGAGTTGCGTTACTCTAGGATATGAGACCTTAGTTCAGAAGTTCAGAAGACAGTACAATCTC
TTGTCAGTACATTTGGCTGCTCACCATGAGGTTAGGAAAGCCTAAGGGGGGTATTTCTCGAAGT
GCAAGCCAAGGAAAAACCTATGAGAGCAAGCGCAAGACAGCCCGCCAGCGACAGAAATGGGGGG
TGGCCATTCGCTTCGACTCAGGGTTAAGTAGACGGAGAAGAAACGTGGATGAGAAGCCTTACAA
ATGTACTAAATGTTCTAAGAGTTTCAGTCAGAGCTCCACTCTTTTTCAGCACAAGAAGATCCAC
ACTGGGAAGAAATCCCATAAATGTGCCGATTGTGGGAAAAGTTTCTTTCAGAGTTCTAACCTCA
TTCAGCATCGGCGGATCCACACGGGGGAAAAGCCCTATAAGTGCGACGAGTGTGGAGAGAGATT
TAAACAGAGCTCCAACCTTATCCAGCACCAGAGGATTCACACCGGGGAGAAGCCCTATTGCTGC
GATGAGTGTGGCCGGTGCTTTAGCCAGAGTTCCCACCTCATTCAGCACCAGAGAACCCACACCG
GAGAAAAGCCCTACCAGTGCGAGGAGTGTGACAAGTGCTTCAGCCAGAGCTCCCACCTGAGGCA
GCACATGAAGGTGCACAAAGAAAAGAAGTCACATAAAAGGGGTAAAAATGCCAGGGCGAAAACT
CACCCGGTGTCCTGGAAACGTGGTAAAGGAAGGAAGGCAGTGGCTGGGCTCCGCCAGGTAAAGG
GAGCCGCTTCGGGCCTTTTCAAAAAGAAGAAGTGAATCTCGTAGCGGTGAAAGCCTCTCCCAAG
AGGGAGGACACTTTACAGTAGATAGAGCACTTAGATACTGGTCCTCCCTAGCATGGAGATGTCA
GGAGTTTCATGACAATGGGCTGAAACTCTGAGTCTAGCCATCCTCATTTCCTTTCAGAATAAAT
AAGTAAATTTATGTGACATGGAGCAGAAAACTGAAAAAAAAGTTTGGTAAGAATTTAACATCCT
TGGCCTCAGTTGAAATTTCTTCCCTACGTTTTGATAAAAAGCGTCATGTTTTCATGATTCACTG
GTGTGCCAATGATTACTCTTGGTTTTAGGAATTTCTGTATACAAAATCATTAAAGAGAAGGAAT
GAGTTTTCAAGTTCTAGGACCGACTATATTTTTAATGTTTTGTAGTTTTTTTTAACCATTAGTA
TCAGCATTGATTCAGTATTTGACATAATAAAATGCATTCAAGTTCATAGATTTTTGTATTTTTT
ATTAGCGTATATTGTATGAAGTAATGAGTTCGTTTTCTTTAATGTGTACGATGTATCTGTATGA
TGTGCTTTGATTATATCCATTGCTCTTACCCTCACCTCCACCTCCTGGTTCTCTTCTTCCTCCC
AGAGAGTTCCCTTCCCACTTGAATTGTTGACCCTGGATTCTGTGAATGACAGAAATTGTCTTTG
GTTATTTTTCCACATCTGCTTTACTGTGTTTACTGTAATGTTCTCCAGTTCTATCCATTTTTCG
CCAAACAACAGGATTTTGGCTTCTTTTTTTTTTTTTTTTAACTAATAAGTTTGTCATAGTGTCT
GATGCTTTAATGAAGGGGTGAAAAGGTCTCCATGTGGCTTTTCTTTTGTTTGTTTTTTGTTTAC
CATATTCTTAGAGATTTCAAAGAATCCAAAGTGAGAAACTGCAGACCTCCTCCTAAGACCATTA
CTTGCGATGCTGATGCCCTGCCTCTTGCTTTCTTGAAATGGGAATGGTTTATGTTGAATCATGC
CAGTGGCCTCTTGGCGTTCCTTTGTTCTCTTGCAAACAGGGCCTGCATGAATAAACTATGTTAC
CAAGAAAGCCTGACTTACTTCTGGCTAAAGAACTACAGTGTCATAGACTGAGCTTTGACTGCCG
CTGACTGAGACAGATGTGTGTCTACAAGTTCCTGGAGCCCTGTTAGAACTTAACTGTTCTTTAC
TTTTTAGCAGTTGTTTAAGAAGACTAGCGGACATCCTTTTTCGAATGCTAAGCCTGAGTTCCTA
GTTAACCCTTAGTTCAAGTTTTTGTTTATTGAATGCTAATGTTTTCTGATTTTTATAATCTCAC
TTCTTCCTGTATTAATGACAATTATCCTCAAAATAAAGATTGAGATATTTTTGCGTA

hide sequence

RefSeq Acc Id:

XM_039107733 ⟹ XP_038963661

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	151,558,254 - 151,565,730 (-)	NCBI
mRatBN7.2	4	149,885,805 - 149,893,287 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012763	(Get FASTA)	NCBI Sequence Viewer
	XP_006237249	(Get FASTA)	NCBI Sequence Viewer
	XP_006237251	(Get FASTA)	NCBI Sequence Viewer
	XP_006237252	(Get FASTA)	NCBI Sequence Viewer
	XP_038963661	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAG12467	(Get FASTA)	NCBI Sequence Viewer
	AAH90354	(Get FASTA)	NCBI Sequence Viewer
	EDM02114	(Get FASTA)	NCBI Sequence Viewer
	EDM02115	(Get FASTA)	NCBI Sequence Viewer
	EDM02116	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000018050
	ENSRNOP00000018050.4
	ENSRNOP00000076367
	ENSRNOP00000076367.1
	ENSRNOP00000085999.1
GenBank Protein	Q9ERU2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001012763 ⟸ NM_001012745

- UniProtKB:

Q9ERU2 (UniProtKB/Swiss-Prot), Q5EAN1 (UniProtKB/Swiss-Prot), A6IL24 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRLGKPKGGISRSASQGKTYESKRKTARQRQKWGVAIRFDSGLSRRRRNVDEKPYKCTKCSKSF
SQSSTLFQHKKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGERFKQSSNLIQ
HQRIHTGEKPYCCDECGRCFSQSSHLIQHQRTHTGEKPYQCEECDKCFSQSSHLRQHMKVHKEK
KSHKRGKNARAKTHPVSWKRGKGRKAVAGLRQVKGAASGLFKKKK

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RefSeq Acc Id:	XP_006237251 ⟸ XM_006237189
- Peptide Label:	isoform X1
- UniProtKB:	Q9ERU2 (UniProtKB/Swiss-Prot), Q5EAN1 (UniProtKB/Swiss-Prot), A6IL24 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRLGKPKGGISRSASQGKTYESKRKTARQRQKWGVAIRFDSGLSRRRRNVDEKPYKCTKCSKSF SQSSTLFQHKKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGERFKQSSNLIQ HQRIHTGEKPYCCDECGRCFSQSSHLIQHQRTHTGEKPYQCEECDKCFSQSSHLRQHMKVHKEK KSHKRGKNARAKTHPVSWKRGKGRKAVAGLRQVKGAASGLFKKKK hide sequence

RefSeq Acc Id:	XP_006237249 ⟸ XM_006237187
- Peptide Label:	isoform X1
- UniProtKB:	Q9ERU2 (UniProtKB/Swiss-Prot), Q5EAN1 (UniProtKB/Swiss-Prot), A6IL24 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRLGKPKGGISRSASQGKTYESKRKTARQRQKWGVAIRFDSGLSRRRRNVDEKPYKCTKCSKSF SQSSTLFQHKKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGERFKQSSNLIQ HQRIHTGEKPYCCDECGRCFSQSSHLIQHQRTHTGEKPYQCEECDKCFSQSSHLRQHMKVHKEK KSHKRGKNARAKTHPVSWKRGKGRKAVAGLRQVKGAASGLFKKKK hide sequence

RefSeq Acc Id:	XP_006237252 ⟸ XM_006237190
- Peptide Label:	isoform X1
- UniProtKB:	Q9ERU2 (UniProtKB/Swiss-Prot), Q5EAN1 (UniProtKB/Swiss-Prot), A6IL24 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRLGKPKGGISRSASQGKTYESKRKTARQRQKWGVAIRFDSGLSRRRRNVDEKPYKCTKCSKSF SQSSTLFQHKKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGERFKQSSNLIQ HQRIHTGEKPYCCDECGRCFSQSSHLIQHQRTHTGEKPYQCEECDKCFSQSSHLRQHMKVHKEK KSHKRGKNARAKTHPVSWKRGKGRKAVAGLRQVKGAASGLFKKKK hide sequence

Ensembl Acc Id:

ENSRNOP00000018050 ⟸ ENSRNOT00000018050

RefSeq Acc Id:	XP_038963661 ⟸ XM_039107733
- Peptide Label:	isoform X1
- UniProtKB:	Q9ERU2 (UniProtKB/Swiss-Prot), Q5EAN1 (UniProtKB/Swiss-Prot), A6IL24 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000085999 ⟸ ENSRNOT00000105818

Ensembl Acc Id:

ENSRNOP00000076367 ⟸ ENSRNOT00000097804

Protein Domains

C2H2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9ERU2-F1-model_v2	AlphaFold	Q9ERU2	1-237	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693336

Promoter ID:

EPDNEW_R3860

Type:

multiple initiation site

Name:

Zfp422_1

Description:

zinc finger protein 422

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	148,761,391 - 148,761,451	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620229	AgrOrtholog
BioCyc Gene	G2FUF-43281	BioCyc
Ensembl Genes	ENSRNOG00000013379	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000018050	ENTREZGENE
	ENSRNOT00000018050.5	UniProtKB/Swiss-Prot
	ENSRNOT00000097804	ENTREZGENE
	ENSRNOT00000097804.1	UniProtKB/Swiss-Prot
	ENSRNOT00000105818.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Classic Zinc Finger	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7319307	IMAGE-MGC_LOAD
InterPro	Znf_C2H2/integrase_DNA-bd	UniProtKB/Swiss-Prot
	Znf_C2H2_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:360389	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105332	IMAGE-MGC_LOAD
NCBI Gene	Zfp422	ENTREZGENE
PANTHER	ZINC FINGER AND SCAN DOMAIN-CONTAINING	UniProtKB/Swiss-Prot
	ZINC FINGER PROTEIN 22	UniProtKB/Swiss-Prot
Pfam	zf-C2H2	UniProtKB/Swiss-Prot
PhenoGen	Zfp422	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000013379	RatGTEx
SMART	ZnF_C2H2	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF57667	UniProtKB/Swiss-Prot
UniProt	A6IL24	ENTREZGENE, UniProtKB/TrEMBL
	Q5EAN1	ENTREZGENE
	Q9ERU2	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q5EAN1	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2007-09-18	Zfp422	zinc finger protein 422	Zfp422_predicted	zinc finger protein 422 (predicted)	Data merged from RGD:1308545	737654	APPROVED
2005-07-08	Zfp422	zinc finger protein 422	Znf22	zinc finger protein 22 (KOX 15)	Symbol and Name updated	1299863	APPROVED
2005-01-12	Zfp422_predicted	zinc finger protein 422 (predicted)			Symbol and Name status set to approved	70820	APPROVED
2002-08-07	Znf22	zinc finger protein 22 (KOX 15)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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