Aprt (adenine phosphoribosyl transferase) - Rat Genome Database

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Gene: Aprt (adenine phosphoribosyl transferase) Rattus norvegicus
Analyze
Symbol: Aprt
Name: adenine phosphoribosyl transferase
RGD ID: 1307758
Description: Enables AMP binding activity. Involved in cellular response to insulin stimulus and lactation. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in adenine phosphoribosyltransferase deficiency. Orthologous to human APRT (adenine phosphoribosyltransferase); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adenine phosphoribosyltransferase; LOC292072
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,534,737 - 67,537,027 (-)NCBIGRCr8
mRatBN7.21950,626,201 - 50,628,491 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,626,202 - 50,628,431 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,421,206 - 57,423,174 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,101,358 - 58,103,326 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,319,830 - 60,321,798 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,387,288 - 55,389,256 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,387,288 - 55,389,256 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,095,804 - 66,097,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,854,657 - 52,856,625 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11952,859,538 - 52,861,506 (-)NCBI
Celera1949,865,842 - 49,867,810 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
dibenzofurans  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
doxorubicin  (EXP,ISO)
epoxiconazole  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
inulin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP,ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nimesulide  (EXP)
ozone  (ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
PhIP  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
trimellitic anhydride  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zearalenone  (ISO)
zidovudine  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)

Molecular Function
adenine binding  (IBA,IEA,ISO)
adenine phosphoribosyltransferase activity  (IBA,IEA,ISO,ISS)
AMP binding  (IBA,IDA,IEA,ISO)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Enzymes of the pathway of purine synthesis in the rat mammary gland. Changes in the lactation cycle and the effects of diabetes. Beardsley S, etal., Biochem J. 1988 Mar 1;250(2):395-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Purification of adenine phosphoribosyltransferase by affinity chromatography. Hershey HV and Taylor MW, Prep Biochem. 1978;8(6):453-62.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Enzymic capacities of purine de Novo and salvage pathways for nucleotide synthesis in normal and neoplastic tissues. Natsumeda Y, etal., Cancer Res. 1984 Jun;44(6):2475-9.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. Identification of two novel mutations in adenine phosphoribosyltransferase gene in patients with 2,8-dihydroxyadenine urolithiasis. Taniguchi A, etal., Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1141-5.
15. Increased de novo purine synthesis by insulin through selective enzyme induction in primary cultured rat hepatocytes. Tsuchiya M, etal., Am J Physiol. 1990 May;258(5 Pt 1):C841-8.
Additional References at PubMed
PMID:198184   PMID:1235912   PMID:6307822   PMID:7323947   PMID:7444718   PMID:8112572   PMID:8485579   PMID:8643571   PMID:8864750   PMID:8894695   PMID:9218001   PMID:15196008  
PMID:19056867   PMID:20458337   PMID:23376485   PMID:23533145   PMID:24625528  


Genomics

Comparative Map Data
Aprt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,534,737 - 67,537,027 (-)NCBIGRCr8
mRatBN7.21950,626,201 - 50,628,491 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,626,202 - 50,628,431 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,421,206 - 57,423,174 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,101,358 - 58,103,326 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,319,830 - 60,321,798 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,387,288 - 55,389,256 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,387,288 - 55,389,256 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,095,804 - 66,097,772 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41952,854,657 - 52,856,625 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11952,859,538 - 52,861,506 (-)NCBI
Celera1949,865,842 - 49,867,810 (-)NCBICelera
Cytogenetic Map19q12NCBI
APRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,809,339 - 88,811,928 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1688,809,339 - 88,811,937 (-)EnsemblGRCh38hg38GRCh38
GRCh371688,875,747 - 88,878,336 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,403,378 - 87,405,843 (-)NCBINCBI36Build 36hg18NCBI36
Build 341687,403,379 - 87,405,879NCBI
Celera1673,944,514 - 73,946,979 (-)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,573,103 - 74,575,568 (-)NCBIHuRef
CHM1_11690,287,144 - 90,289,609 (-)NCBICHM1_1
T2T-CHM13v2.01694,879,859 - 94,882,448 (-)NCBIT2T-CHM13v2.0
Aprt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,301,376 - 123,303,646 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,301,374 - 123,303,648 (-)EnsemblGRCm39 Ensembl
GRCm388122,574,637 - 122,576,907 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,574,635 - 122,576,909 (-)EnsemblGRCm38mm10GRCm38
MGSCv378125,098,537 - 125,100,807 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368125,460,727 - 125,462,950 (-)NCBIMGSCv36mm8
Celera8126,804,235 - 126,806,505 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.91NCBI
Aprt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,687,938 - 2,690,906 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,687,938 - 2,690,906 (-)NCBIChiLan1.0ChiLan1.0
APRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,582,498 - 98,585,192 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,494,670 - 104,497,177 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,522,628 - 69,525,138 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,179,020 - 89,181,505 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,179,020 - 89,181,504 (-)Ensemblpanpan1.1panPan2
APRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,563,154 - 64,565,537 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,563,192 - 64,565,445 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,574,619 - 64,577,004 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,783,377 - 64,785,760 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,783,416 - 64,785,668 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,809,556 - 64,811,939 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,641,062 - 64,643,445 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0565,047,101 - 65,049,491 (+)NCBIUU_Cfam_GSD_1.0
Aprt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934925,160,104 - 25,162,762 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641913,475 - 918,748 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936641913,674 - 916,312 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6890,831 - 893,276 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16890,272 - 893,278 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.261,090,009 - 1,092,413 (-)NCBISscrofa10.2Sscrofa10.2susScr3
APRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,196,858 - 74,199,789 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,194,013 - 74,199,891 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660471,479,268 - 1,482,118 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aprt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746805,758 - 807,963 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746805,742 - 807,963 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aprt
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:42
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000064180
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194997648153225766Rat

Markers in Region
Aprt  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21950,626,747 - 50,627,000 (+)MAPPERmRatBN7.2
Rnor_6.01955,387,600 - 55,387,852NCBIRnor6.0
Rnor_5.01966,096,116 - 66,096,368UniSTSRnor5.0
RGSC_v3.41952,854,969 - 52,855,221UniSTSRGSC3.4
Celera1949,866,154 - 49,866,406UniSTS
Cytogenetic Map19q12UniSTS
RH127914  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21950,626,447 - 50,626,763 (+)MAPPERmRatBN7.2
Rnor_6.01955,387,300 - 55,387,615NCBIRnor6.0
Rnor_5.01966,095,816 - 66,096,131UniSTSRnor5.0
RGSC_v3.41952,854,669 - 52,854,984UniSTSRGSC3.4
Celera1949,865,854 - 49,866,169UniSTS
RH 3.4 Map19699.71UniSTS
Cytogenetic Map19q12UniSTS
RH94458  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21950,626,416 - 50,626,575 (+)MAPPERmRatBN7.2
Rnor_6.01955,387,269 - 55,387,427NCBIRnor6.0
Rnor_5.01966,095,785 - 66,095,943UniSTSRnor5.0
RGSC_v3.41952,854,638 - 52,854,796UniSTSRGSC3.4
Celera1949,865,823 - 49,865,981UniSTS
Cytogenetic Map19q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 40 11 8
Low 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000064180   ⟹   ENSRNOP00000061449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1950,626,202 - 50,628,431 (-)Ensembl
Rnor_6.0 Ensembl1955,387,288 - 55,389,256 (-)Ensembl
RefSeq Acc Id: NM_001013061   ⟹   NP_001013079
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81967,534,737 - 67,537,027 (-)NCBI
mRatBN7.21950,626,201 - 50,628,491 (-)NCBI
Rnor_6.01955,387,288 - 55,389,256 (-)NCBI
Rnor_5.01966,095,804 - 66,097,772 (-)NCBI
RGSC_v3.41952,854,657 - 52,856,625 (-)RGD
Celera1949,865,842 - 49,867,810 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001013079 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40757 (Get FASTA)   NCBI Sequence Viewer  
  EDL92756 (Get FASTA)   NCBI Sequence Viewer  
  EDL92757 (Get FASTA)   NCBI Sequence Viewer  
  EDL92758 (Get FASTA)   NCBI Sequence Viewer  
  EDL92759 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000061449
  ENSRNOP00000061449.2
GenBank Protein P36972 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001013079   ⟸   NM_001013061
- UniProtKB: P36972 (UniProtKB/Swiss-Prot),   A0A8L2QU71 (UniProtKB/TrEMBL),   A6IZS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000061449   ⟸   ENSRNOT00000064180
Protein Domains
Phosphoribosyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P36972-F1-model_v2 AlphaFold P36972 1-180 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701212
Promoter ID:EPDNEW_R11735
Type:initiation region
Name:Aprt_1
Description:adenine phosphoribosyl transferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01955,389,287 - 55,389,347EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307758 AgrOrtholog
BioCyc Gene G2FUF-5381 BioCyc
BioCyc Pathway P121-PWY [adenine and adenosine salvage I] BioCyc
BioCyc Pathway Image P121-PWY BioCyc
Ensembl Genes ENSRNOG00000014405 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064180 ENTREZGENE
  ENSRNOT00000064180.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.2020 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ade_phspho_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRibTrfase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRTase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:292072 UniProtKB/Swiss-Prot
NCBI Gene 292072 ENTREZGENE
PANTHER ADENINE PHOSPHORIBOSYLTRANSFERASE UniProtKB/Swiss-Prot
  ADENINE PHOSPHORIBOSYLTRANSFERASE UniProtKB/Swiss-Prot
  ADENINE PHOSPHORIBOSYLTRANSFERASE UniProtKB/TrEMBL
  ADENINE PHOSPHORIBOSYLTRANSFERASE UniProtKB/TrEMBL
Pfam Pribosyltran UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aprt PhenoGen
PROSITE PUR_PYR_PR_TRANSFER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014405 RatGTEx
Superfamily-SCOP SSF53271 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2QU71 ENTREZGENE, UniProtKB/TrEMBL
  A6IZS8 ENTREZGENE, UniProtKB/TrEMBL
  APT_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Aprt  adenine phosphoribosyl transferase   Aprt_predicted  adenine phosphoribosyl transferase (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Aprt_predicted  adenine phosphoribosyl transferase (predicted)      Symbol and Name status set to approved 70820 APPROVED