Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Chemical and Drug Induced Liver Injury | | ISO | ABI1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25231249 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Chemical and Drug Induced Liver Injury | | ISO | ABI1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25231249 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation. | Ito H, etal., Mol Psychiatry. 2010 Oct;15(10):976-86. doi: 10.1038/mp.2010.69. Epub 2010 Jun 8. |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
5. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
6. | Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation. | Proepper C, etal., EMBO J. 2007 Mar 7;26(5):1397-409. Epub 2007 Feb 15. |
7. | Heterogeneous nuclear ribonucleoprotein k interacts with Abi-1 at postsynaptic sites and modulates dendritic spine morphology. | Proepper C, etal., PLoS One. 2011;6(11):e27045. doi: 10.1371/journal.pone.0027045. Epub 2011 Nov 15. |
8. | GOA pipeline | RGD automated data pipeline |
9. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
10. | Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton. | Ziemnicka-Kotula D, etal., J Biol Chem 1998 May 29;273(22):13681-92. |
PMID:10995551 | PMID:11516653 | PMID:12477932 | PMID:12672821 | PMID:15755804 | PMID:16831833 | PMID:17101133 | PMID:17664349 | PMID:18560548 | PMID:19056867 | PMID:19200726 | PMID:19798448 |
PMID:21107423 | PMID:21464958 | PMID:21795692 | PMID:25297099 | PMID:25468996 | PMID:30053369 |
Abi1 (Rattus norvegicus - Norway rat) |
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ABI1 (Homo sapiens - human) |
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Abi1 (Mus musculus - house mouse) |
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Abi1 (Chinchilla lanigera - long-tailed chinchilla) |
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ABI1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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ABI1 (Canis lupus familiaris - dog) |
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Abi1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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ABI1 (Sus scrofa - pig) |
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ABI1 (Chlorocebus sabaeus - green monkey) |
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Abi1 (Heterocephalus glaber - naked mole-rat) |
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Variants in Abi1
116 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
D17Rat51 |
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RH127345 |
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RH137994 |
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AI009242 |
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AU049482 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 42 | 57 | 41 | 19 | 41 | 8 | 9 | 74 | 35 | 38 | 11 | 8 |
Low | 1 | 2 | 3 | ||||||||||
Below cutoff |
RefSeq Transcripts | NM_024397 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006254353 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006254354 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006254355 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006254356 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006254357 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006254358 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006254359 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006254360 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039096101 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039096103 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AF176784 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC129092 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CB725283 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH474100 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000017 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000057572 ⟹ ENSRNOP00000054381 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000091023 ⟹ ENSRNOP00000071079 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000093928 ⟹ ENSRNOP00000081022 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000103736 ⟹ ENSRNOP00000085236 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000108948 ⟹ ENSRNOP00000093871 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_024397 ⟹ NP_077373 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254353 ⟹ XP_006254415 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254354 ⟹ XP_006254416 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254355 ⟹ XP_006254417 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254356 ⟹ XP_006254418 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254357 ⟹ XP_006254419 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254358 ⟹ XP_006254420 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254359 ⟹ XP_006254421 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006254360 ⟹ XP_006254422 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039096101 ⟹ XP_038952029 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039096103 ⟹ XP_038952031 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Protein RefSeqs | NP_077373 | (Get FASTA) | NCBI Sequence Viewer |
XP_006254415 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006254416 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006254417 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006254418 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006254419 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006254420 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006254421 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006254422 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038952029 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038952031 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAD55263 | (Get FASTA) | NCBI Sequence Viewer |
AAI29093 | (Get FASTA) | NCBI Sequence Viewer | |
EDL83933 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000054381 | ||
ENSRNOP00000054381.4 | |||
ENSRNOP00000071079 | |||
ENSRNOP00000071079.2 | |||
ENSRNOP00000081022 | |||
ENSRNOP00000081022.1 | |||
ENSRNOP00000085236.1 | |||
ENSRNOP00000093871 | |||
ENSRNOP00000093871.1 | |||
GenBank Protein | Q9QZM5 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_077373 ⟸ NM_024397 |
- UniProtKB: | A2VD09 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006254422 ⟸ XM_006254360 |
- Peptide Label: | isoform X5 |
- Sequence: |
RefSeq Acc Id: | XP_006254418 ⟸ XM_006254356 |
- Peptide Label: | isoform X4 |
- Sequence: |
RefSeq Acc Id: | XP_006254415 ⟸ XM_006254353 |
- Peptide Label: | isoform X1 |
- Sequence: |
RefSeq Acc Id: | XP_006254420 ⟸ XM_006254358 |
- Peptide Label: | isoform X9 |
- UniProtKB: | A0A8I5ZQS1 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006254416 ⟸ XM_006254354 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q9QZM5 (UniProtKB/Swiss-Prot), A6KRZ5 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006254417 ⟸ XM_006254355 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A8L2UQ93 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006254419 ⟸ XM_006254357 |
- Peptide Label: | isoform X7 |
- Sequence: |
RefSeq Acc Id: | XP_006254421 ⟸ XM_006254359 |
- Peptide Label: | isoform X10 |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000054381 ⟸ ENSRNOT00000057572 |
RefSeq Acc Id: | ENSRNOP00000071079 ⟸ ENSRNOT00000091023 |
RefSeq Acc Id: | XP_038952029 ⟸ XM_039096101 |
- Peptide Label: | isoform X6 |
- UniProtKB: | A0A8I6AGM2 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038952031 ⟸ XM_039096103 |
- Peptide Label: | isoform X8 |
RefSeq Acc Id: | ENSRNOP00000081022 ⟸ ENSRNOT00000093928 |
RefSeq Acc Id: | ENSRNOP00000093871 ⟸ ENSRNOT00000108948 |
RefSeq Acc Id: | ENSRNOP00000085236 ⟸ ENSRNOT00000103736 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9QZM5-F1-model_v2 | AlphaFold | Q9QZM5 | 1-476 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13700617 | ||||||||
Promoter ID: | EPDNEW_R11140 | ||||||||
Type: | initiation region | ||||||||
Name: | Abi1_1 | ||||||||
Description: | abl-interactor 1 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:621008 | AgrOrtholog |
BioCyc Gene | G2FUF-8481 | BioCyc |
Ensembl Genes | ENSRNOG00000031325 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000057572 | ENTREZGENE |
ENSRNOT00000057572.5 | UniProtKB/TrEMBL | |
ENSRNOT00000091023.2 | UniProtKB/TrEMBL | |
ENSRNOT00000093928.1 | UniProtKB/TrEMBL | |
ENSRNOT00000103736.1 | UniProtKB/TrEMBL | |
ENSRNOT00000108948.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 6.10.140.1620 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SH3 Domains | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7192971 | IMAGE-MGC_LOAD |
InterPro | ABI | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Abi1_SH3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Abl-interactor_HHR_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SH3-like_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SH3_domain | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
T_SNARE_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:79249 | UniProtKB/TrEMBL |
MGC_CLONE | MGC:156634 | IMAGE-MGC_LOAD |
NCBI Gene | 79249 | ENTREZGENE |
PANTHER | PTHR10460 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR10460:SF2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Abi_HHR | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SH3_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Abi1 | PhenoGen |
PRINTS | P67PHOX | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SH3DOMAIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROSITE | SH3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
T_SNARE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000031325 | RatGTEx |
SMART | SH3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF50044 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A8I5ZQS1 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6A0X0_RAT | UniProtKB/TrEMBL | |
A0A8I6AGM2 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8L2UQ93 | ENTREZGENE, UniProtKB/TrEMBL | |
A2VD09 | ENTREZGENE, UniProtKB/TrEMBL | |
A6KRZ5 | ENTREZGENE, UniProtKB/TrEMBL | |
ABI1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2005-01-20 | Abi1 | abl-interactor 1 | eps8 binding protein (e3B1), alternatively spliced | Name updated | 1299863 | APPROVED | |
2002-08-07 | Abi1 | eps8 binding protein (e3B1), alternatively spliced | Symbol and Name status set to provisional | 70820 | PROVISIONAL |