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Gene: Nelfe (negative elongation factor complex member E) Rattus norvegicus
Symbol: Nelfe
Name: negative elongation factor complex member E
Description: Exhibits chromatin binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of macromolecule metabolic process. Localizes to the nucleus. Orthologous to human NELFE (negative elongation factor complex member E); PARTICIPATES IN RNA polymerase II transcription elongation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: negative elongation factor E; Rd; RD RNA-binding protein; Rdbp
Homo sapiens (human) : NELFE (negative elongation factor complex member E)  HGNC  Alliance
Mus musculus (house mouse) : Nelfe (negative elongation factor complex member E, Rdbp)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nelfe (negative elongation factor complex member E)
Pan paniscus (bonobo/pygmy chimpanzee) : NELFE (negative elongation factor complex member E)
Canis lupus familiaris (dog) : NELFE (negative elongation factor complex member E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nelfe (negative elongation factor complex member E)
Sus scrofa (pig) : NELFE (negative elongation factor complex member E)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0204,530,328 - 4,536,085 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,530,342 - 4,536,209 (+)Ensembl
Rnor_5.0206,610,127 - 6,615,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,077,925 - 4,081,561 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,078,021 - 4,081,787 (-)NCBI
Celera204,048,306 - 4,054,061 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nelfe
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303325
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.