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Gene: HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0) Homo sapiens

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Symbol:

HNRNPA0

Name:

heterogeneous nuclear ribonucleoprotein A0

RGD ID:

1318867

HGNC Page

HGNC:5030

Description:

Enables mRNA 3'-UTR AU-rich region binding activity and protein kinase binding activity. Predicted to be involved in 3'-UTR-mediated mRNA stabilization; inflammatory response; and response to lipopolysaccharide. Located in nucleoplasm. Biomarker of gastric adenocarcinoma.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

hnRNA binding protein; hnRNP A0; HNRPA0

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	137,745,651 - 137,754,363 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	137,745,651 - 137,754,363 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	137,081,340 - 137,090,052 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	137,114,972 - 137,117,938 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	137,114,973 - 137,117,938	NCBI
Celera	5	133,208,508 - 133,211,474 (-)	NCBI		Celera
Cytogenetic Map	5	q31.2	NCBI
HuRef	5	132,277,733 - 132,280,699 (-)	NCBI		HuRef
CHM1_1	5	136,519,671 - 136,522,637 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	138,271,491 - 138,280,204 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant intellectual developmental disorder 31 (IAGP)

familial adenomatous polyposis 1 (IAGP)

gastric adenocarcinoma (IEP)

Hereditary Neoplastic Syndromes (IAGP)

Neurodevelopmental Disorders (IAGP)

STING-associated vasculopathy with onset in infancy (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,6-dimethoxyphenol (EXP)

2-hydroxypropanoic acid (EXP)

3',5'-cyclic UMP (EXP)

3,3',5,5'-tetrabromobisphenol A (EXP)

3-chloropropane-1,2-diol (ISO)

aflatoxin B1 (EXP)

antirheumatic drug (EXP)

atrazine (EXP)

benzo[a]pyrene (EXP,ISO)

benzo[a]pyrene diol epoxide I (EXP)

bis(2-chloroethyl) sulfide (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (ISO)

bisphenol AF (EXP)

Bisphenol B (EXP)

cadmium atom (EXP)

cadmium dichloride (EXP)

calyculin a (ISO)

carbon nanotube (ISO)

chloropicrin (EXP)

chromium(6+) (EXP)

copper(II) chloride (EXP)

cyclosporin A (EXP)

dextran sulfate (ISO)

dibutyl phthalate (ISO)

diethylstilbestrol (EXP)

doxorubicin (EXP)

enzyme inhibitor (EXP)

folic acid (ISO)

FR900359 (EXP)

hydrogen peroxide (EXP)

ivermectin (EXP)

lead diacetate (EXP)

lead(0) (EXP)

leflunomide (EXP)

methapyrilene (ISO)

methylparaben (EXP)

nitrates (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (EXP)

propylparaben (EXP)

quercetin (EXP)

rac-lactic acid (EXP)

SB 431542 (EXP)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (EXP)

sodium chloride (EXP)

sunitinib (EXP)

tetracaine (EXP,ISO)

tetrachloromethane (ISO)

thimerosal (EXP)

thiram (EXP)

titanium dioxide (ISO)

triphenyl phosphate (EXP)

troglitazone (ISO)

tunicamycin (EXP)

valproic acid (EXP)

vorinostat (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

3'-UTR-mediated mRNA stabilization (IBA,IEA,ISS,TAS)

inflammatory response (IEA,ISS)

mRNA processing (TAS)

response to lipopolysaccharide (IEA,ISS)

Cellular Component

nucleoplasm (IDA)

nucleus (IBA,IEA,TAS)

ribonucleoprotein complex (IEA)

synapse (IEA,ISO)

Molecular Function

mRNA 3'-UTR AU-rich region binding (IDA,IEA)

mRNA binding (IBA)

protein binding (IPI)

protein kinase binding (IPI)

RNA binding (HDA,IEA,TAS)

Molecular Pathway Annotations Click to see Annotation Detail View

spliceosome pathway (TAS)

References

References - curated

#	Reference Title	Reference Citation
1.	Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.	Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
2.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Identification of recurrence-related genes by integrating microRNA and gene expression profiling of gastric cancer.	Yan Z, etal., Int J Oncol. 2012 Dec;41(6):2166-74. doi: 10.3892/ijo.2012.1637. Epub 2012 Sep 24.

Additional References at PubMed

PMID:1602151	PMID:7585247	PMID:8012384	PMID:8325628	PMID:8889548	PMID:8889549	PMID:11161817	PMID:12226669	PMID:12456657	PMID:12477932	PMID:12565831	PMID:15489334
PMID:15592455	PMID:15635413	PMID:15782174	PMID:16169070	PMID:16196087	PMID:17215244	PMID:17314511	PMID:17620599	PMID:17643375	PMID:18029348	PMID:18457437	PMID:18816836
PMID:19165527	PMID:19322201	PMID:19738201	PMID:20020773	PMID:20360068	PMID:20467437	PMID:20932473	PMID:21081503	PMID:21145461	PMID:21182205	PMID:21873635	PMID:21900206
PMID:22199357	PMID:22365833	PMID:22412018	PMID:22623428	PMID:22658674	PMID:22681889	PMID:22863883	PMID:22939629	PMID:23125841	PMID:23151878	PMID:23184937	PMID:23277564
PMID:23402259	PMID:24332808	PMID:24457600	PMID:24532040	PMID:24711643	PMID:25324306	PMID:25437307	PMID:25515538	PMID:25798074	PMID:25852190	PMID:25900982	PMID:25921289
PMID:26167880	PMID:26318153	PMID:26496610	PMID:26514267	PMID:26549023	PMID:26602816	PMID:26641092	PMID:26760575	PMID:26831064	PMID:26979993	PMID:27025967	PMID:27248496
PMID:27576135	PMID:27609421	PMID:27684187	PMID:27976729	PMID:28225217	PMID:28302793	PMID:28431233	PMID:28515276	PMID:28973437	PMID:28977666	PMID:28978906	PMID:29053956
PMID:29117863	PMID:29229926	PMID:29298432	PMID:29467282	PMID:29478914	PMID:29511296	PMID:29653964	PMID:29777862	PMID:29802200	PMID:29845934	PMID:29884807	PMID:29991511
PMID:30021884	PMID:30097533	PMID:30196744	PMID:30209976	PMID:30349055	PMID:30415952	PMID:30425250	PMID:30463901	PMID:30532072	PMID:30804502	PMID:30833792	PMID:30884312
PMID:30940648	PMID:30948266	PMID:31048545	PMID:31059266	PMID:31091453	PMID:31180492	PMID:31239290	PMID:31353912	PMID:31586073	PMID:31796584	PMID:31980649	PMID:32041737
PMID:32129710	PMID:32176739	PMID:32457219	PMID:32521226	PMID:32529326	PMID:32665550	PMID:32694731	PMID:32780723	PMID:32786267	PMID:32807901	PMID:33022573	PMID:33239621
PMID:33306668	PMID:33545068	PMID:33567341	PMID:33658012	PMID:33729478	PMID:33766124	PMID:33957083	PMID:34079125	PMID:34091597	PMID:34133714	PMID:34189442	PMID:34244482
PMID:34316702	PMID:34349018	PMID:34551306	PMID:34578187	PMID:34650049	PMID:34709727	PMID:34732716	PMID:34767673	PMID:34821009	PMID:35013218	PMID:35031058	PMID:35182466
PMID:35198878	PMID:35235311	PMID:35256949	PMID:35271311	PMID:35546148	PMID:35563538	PMID:35575683	PMID:35676659	PMID:35785414	PMID:35831314	PMID:35850772	PMID:35944360
PMID:35987950	PMID:36057605	PMID:36114006	PMID:36180527	PMID:36199071	PMID:36215168	PMID:36217030	PMID:36373674	PMID:36424410	PMID:36490346	PMID:36526897	PMID:36574265
PMID:36634849	PMID:36779763	PMID:37039823	PMID:37151849	PMID:37223481	PMID:37314180	PMID:37314216	PMID:37317656	PMID:37448957	PMID:37616343	PMID:37640791	PMID:37794589
PMID:37827155	PMID:38113892	PMID:38172120	PMID:38334954	PMID:38697112	PMID:38803224	PMID:38865811	PMID:38899932	PMID:39506849

Genomics

Comparative Map Data

HNRNPA0
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	137,745,651 - 137,754,363 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	137,745,651 - 137,754,363 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	137,081,340 - 137,090,052 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	137,114,972 - 137,117,938 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	137,114,973 - 137,117,938	NCBI
Celera	5	133,208,508 - 133,211,474 (-)	NCBI		Celera
Cytogenetic Map	5	q31.2	NCBI
HuRef	5	132,277,733 - 132,280,699 (-)	NCBI		HuRef
CHM1_1	5	136,519,671 - 136,522,637 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	138,271,491 - 138,280,204 (-)	NCBI		T2T-CHM13v2.0

Hnrnpa0
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	58,273,693 - 58,276,370 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	58,273,693 - 58,276,370 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	58,125,879 - 58,128,556 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	58,125,879 - 58,128,556 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	58,227,240 - 58,229,917 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	58,135,497 - 58,138,179 (-)	NCBI		MGSCv36	mm8
Celera	13	59,188,312 - 59,191,005 (-)	NCBI		Celera
Cytogenetic Map	13	B1	NCBI
cM Map	13	30.95	NCBI

Hnrnpa0
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	6,513,129 - 6,515,786 (+)	NCBI		GRCr8
mRatBN7.2	17	6,507,728 - 6,510,385 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	6,507,275 - 6,509,375 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	6,531,408 - 6,534,065 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	8,062,954 - 8,065,610 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	6,527,780 - 6,530,437 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	6,909,166 - 6,912,145 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	6,909,728 - 6,910,630 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	9,112,278 - 9,114,786 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	12,452,030 - 12,452,914 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.4	17	12,447,411 - 12,452,914 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	6,617,417 - 6,619,591 (+)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

Hnrnpa0
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955408	32,718,736 - 32,719,409 (-)	NCBI	ChiLan1.0	ChiLan1.0

HNRNPA0
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	133,033,434 - 133,039,146 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	131,172,992 - 131,178,704 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	133,132,030 - 133,140,771 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	139,275,249 - 139,278,250 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	139,277,004 - 139,277,939 (-)	Ensembl	panpan1.1		panPan2

HNRNPA0
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	25,464,601 - 25,467,460 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	25,466,185 - 25,467,117 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	24,221,624 - 24,224,449 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	26,307,823 - 26,310,665 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	11	25,015,201 - 25,018,057 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	24,839,048 - 24,841,888 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	25,501,674 - 25,504,531 (-)	NCBI		UU_Cfam_GSD_1.0

Hnrnpa0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	125,687,294 - 125,690,045 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936597	4,712,201 - 4,714,949 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HNRNPA0
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	139,779,867 - 139,783,159 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	139,779,865 - 139,783,016 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	145,501,462 - 145,504,543 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HNRNPA0
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	40,433,429 - 40,436,188 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	40,435,002 - 40,435,913 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	37,455,662 - 37,458,472 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hnrnpa0
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	9,266,607 - 9,267,527 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	9,265,784 - 9,271,559 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in HNRNPA0
11 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 5q23.3-33.2(chr5:130860928-155321811)x3	copy number gain	See cases [RCV000051193]	Chr5:130860928..155321811 [GRCh38] Chr5:130196621..154701371 [GRCh37] Chr5:130224520..154681564 [NCBI36] Chr5:5q23.3-33.2	pathogenic
GRCh38/hg38 5q31.1-31.2(chr5:133401565-138437038)x1	copy number loss	See cases [RCV000052114]	Chr5:133401565..138437038 [GRCh38] Chr5:132737257..137772727 [GRCh37] Chr5:132765156..137800626 [NCBI36] Chr5:5q31.1-31.2	pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1	copy number loss	See cases [RCV000053524]	Chr5:106619588..156124387 [GRCh38] Chr5:105955289..155551397 [GRCh37] Chr5:105983188..155483975 [NCBI36] Chr5:5q21.3-33.2	pathogenic
GRCh38/hg38 5q31.1-31.3(chr5:135297294-140106003)x3	copy number gain	See cases [RCV000133750]	Chr5:135297294..140106003 [GRCh38] Chr5:134632984..139485588 [GRCh37] Chr5:134660883..139465772 [NCBI36] Chr5:5q31.1-31.3	pathogenic
GRCh38/hg38 5q23.3-33.2(chr5:129847794-153353546)x3	copy number gain	See cases [RCV000138808]	Chr5:129847794..153353546 [GRCh38] Chr5:129183487..152733106 [GRCh37] Chr5:129211386..152713299 [NCBI36] Chr5:5q23.3-33.2	pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3	copy number gain	not provided [RCV000487658]	Chr5:94844077..178830410 [GRCh37] Chr5:5q15-35.3	likely benign
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910)x3	copy number gain	See cases [RCV000449349]	Chr5:130125085..157574910 [GRCh37] Chr5:5q23.3-33.3	pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)	copy number gain	See cases [RCV000510723]	Chr5:113577..180719789 [GRCh37] Chr5:5p15.33-q35.3	pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3	copy number gain	See cases [RCV000448245]	Chr5:106716357..180687338 [GRCh37] Chr5:5q21.3-35.3	pathogenic
GRCh37/hg19 5q31.2(chr5:136667092-137380603)x3	copy number gain	See cases [RCV000447839]	Chr5:136667092..137380603 [GRCh37] Chr5:5q31.2	uncertain significance
NC_000005.9:g.(?_86400000)_(154000000_?)del	deletion	Familial adenomatous polyposis 1 [RCV004561496]\|Hereditary cancer-predisposing syndrome [RCV000554476]	Chr5:86400000..154000000 [GRCh37] Chr5:5q14.3-33.2	pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1	copy number loss	See cases [RCV000511978]	Chr5:17628741..176575720 [GRCh37] Chr5:5p15.1-q35.2	pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3	copy number gain	See cases [RCV000512039]	Chr5:113577..180719789 [GRCh37] Chr5:5p15.33-q35.3	pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3	copy number gain	not provided [RCV000744323]	Chr5:25328..180693344 [GRCh37] Chr5:5p15.33-q35.3	pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3	copy number gain	not provided [RCV000744317]	Chr5:13648..180905029 [GRCh37] Chr5:5p15.33-q35.3	pathogenic
Single allele	deletion	Neurodevelopmental disorder [RCV000787436]	Chr5:14685137..149511942 [GRCh37] Chr5:5p15.2-q32	uncertain significance
NM_006805.4(HNRNPA0):c.516A>G (p.Lys172=)	single nucleotide variant	not provided [RCV000880786]	Chr5:137753551 [GRCh38] Chr5:137089240 [GRCh37] Chr5:5q31.2	benign
NC_000005.9:g.(?_136633338)_(140998481_?)dup	duplication	PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome [RCV001339088]	Chr5:136633338..140998481 [GRCh37] Chr5:5q31.2-31.3	uncertain significance
GRCh37/hg19 5q31.2(chr5:136409875-137739167)	copy number loss	Microcephaly [RCV001352638]	Chr5:136409875..137739167 [GRCh37] Chr5:5q31.2	pathogenic
GRCh37/hg19 5q31.1-31.2(chr5:132031902-137623639)	copy number loss	not specified [RCV002053530]	Chr5:132031902..137623639 [GRCh37] Chr5:5q31.1-31.2	pathogenic
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910)	copy number gain	not specified [RCV002053526]	Chr5:130125085..157574910 [GRCh37] Chr5:5q23.3-33.3	pathogenic
NC_000005.9:g.(?_136957787)_(140078137_?)dup	duplication	PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome [RCV003116437]	Chr5:136957787..140078137 [GRCh37] Chr5:5q31.2-31.3	uncertain significance
NC_000005.9:g.(?_136957787)_(138861289_?)del	deletion	STING-associated vasculopathy with onset in infancy [RCV003113978]	Chr5:136957787..138861289 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.650A>T (p.Tyr217Phe)	single nucleotide variant	not specified [RCV004311043]	Chr5:137753417 [GRCh38] Chr5:137089106 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.580G>T (p.Gly194Cys)	single nucleotide variant	not specified [RCV004204941]	Chr5:137753487 [GRCh38] Chr5:137089176 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.656G>A (p.Ser219Asn)	single nucleotide variant	not specified [RCV004104547]	Chr5:137753411 [GRCh38] Chr5:137089100 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.607G>A (p.Gly203Ser)	single nucleotide variant	not specified [RCV004079748]	Chr5:137753460 [GRCh38] Chr5:137089149 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.382G>C (p.Glu128Gln)	single nucleotide variant	not specified [RCV004215502]	Chr5:137753685 [GRCh38] Chr5:137089374 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.659A>T (p.Tyr220Phe)	single nucleotide variant	not specified [RCV004184781]	Chr5:137753408 [GRCh38] Chr5:137089097 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.349C>T (p.His117Tyr)	single nucleotide variant	not specified [RCV004318848]	Chr5:137753718 [GRCh38] Chr5:137089407 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.613G>T (p.Asp205Tyr)	single nucleotide variant	not specified [RCV004265183]	Chr5:137753454 [GRCh38] Chr5:137089143 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.895G>A (p.Gly299Ser)	single nucleotide variant	not specified [RCV004632908]	Chr5:137753172 [GRCh38] Chr5:137088861 [GRCh37] Chr5:5q31.2	uncertain significance
NM_006805.4(HNRNPA0):c.904G>A (p.Gly302Ser)	single nucleotide variant	not specified [RCV004632909]	Chr5:137753163 [GRCh38] Chr5:137088852 [GRCh37] Chr5:5q31.2	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	574
Count of miRNA genes:	450
Interacting mature miRNAs:	485
Transcripts:	ENST00000314940
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCh38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597192076	GWAS1288150_H	educational attainment QTL GWAS1288150 (human)		3e-13	educational attainment		5	137749544	137749545	Human
1357314	AASTH54_H	Allergic/atopic asthma related QTL 54 (human)	3.56	0.0003	Reversible airflow obstruction	total serum IgE	5	135892246	150155845	Human

Markers in Region

RH12646

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	137,087,101 - 137,087,243	UniSTS	GRCh37
Build 36	5	137,115,000 - 137,115,142	RGD	NCBI36
Celera	5	133,208,536 - 133,208,678	RGD
Cytogenetic Map	5	q31	UniSTS
HuRef	5	132,277,761 - 132,277,903	UniSTS
GeneMap99-GB4 RH Map	5	520.62	UniSTS

RH70163

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	137,089,263 - 137,089,394	UniSTS	GRCh37
Build 36	5	137,117,162 - 137,117,293	RGD	NCBI36
Celera	5	133,210,698 - 133,210,829	RGD
Cytogenetic Map	5	q31	UniSTS
HuRef	5	132,279,923 - 132,280,054	UniSTS
GeneMap99-GB4 RH Map	5	520.52	UniSTS

RH79130

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	137,088,407 - 137,088,533	UniSTS	GRCh37
Build 36	5	137,116,306 - 137,116,432	RGD	NCBI36
Celera	5	133,209,842 - 133,209,968	RGD
Cytogenetic Map	5	q31	UniSTS
HuRef	5	132,279,067 - 132,279,193	UniSTS
GeneMap99-GB4 RH Map	5	520.39	UniSTS

D5F121S1

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	137,088,897 - 137,089,147	UniSTS	GRCh37
Build 36	5	137,116,796 - 137,117,046	RGD	NCBI36
Celera	5	133,210,332 - 133,210,582	RGD
Cytogenetic Map	5	q31	UniSTS
HuRef	5	132,279,557 - 132,279,807	UniSTS

G20772

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	137,087,356 - 137,087,479	UniSTS	GRCh37
Build 36	5	137,115,255 - 137,115,378	RGD	NCBI36
Celera	5	133,208,791 - 133,208,914	RGD
Cytogenetic Map	5	q31	UniSTS
HuRef	5	132,278,016 - 132,278,139	UniSTS

A006F37

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	137,087,356 - 137,087,479	UniSTS	GRCh37
Build 36	5	137,115,255 - 137,115,378	RGD	NCBI36
Celera	5	133,208,791 - 133,208,914	RGD
Cytogenetic Map	5	q31	UniSTS
HuRef	5	132,278,016 - 132,278,139	UniSTS
GeneMap99-GB4 RH Map	5	520.62	UniSTS

HNRPA0_2045

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	5	137,088,216 - 137,089,104	UniSTS	GRCh37
Build 36	5	137,116,115 - 137,117,003	RGD	NCBI36
Celera	5	133,209,651 - 133,210,539	RGD
HuRef	5	132,278,876 - 132,279,764	UniSTS

AA858784

Human Assembly	Chr	Position (strand)	Source	JBrowse
HuRef	5	132,279,098 - 132,279,242	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1204	2439	2788	2253	4974	1726	2351	6	624	1951	465	2270	7306	6472	53	3734	1	852	1744	1617	175	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_006805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA081021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AA442538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC106791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK311328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC001008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC007271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC009284	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC011972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC012490	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC012980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC018800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC018949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC019271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC028976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC030249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF445078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BM968394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR456986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB887001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC944410	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KT584573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L10372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U23803	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Z61116	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000314940 ⟹ ENSP00000316042

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	5	137,745,651 - 137,754,363 (-)	Ensembl

Ensembl Acc Id:

ENST00000705031 ⟹ ENSP00000516066

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	5	137,745,651 - 137,754,363 (-)	Ensembl

RefSeq Acc Id:

NM_006805 ⟹ NP_006796

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	5	137,745,651 - 137,754,363 (-)	NCBI
GRCh37	5	137,087,073 - 137,090,039 (-)	RGD
Build 36	5	137,114,972 - 137,117,938 (-)	NCBI Archive
Celera	5	133,208,508 - 133,211,474 (-)	RGD
HuRef	5	132,277,733 - 132,280,699 (-)	ENTREZGENE
CHM1_1	5	136,519,671 - 136,522,637 (-)	NCBI
T2T-CHM13v2.0	5	138,271,491 - 138,280,204 (-)	NCBI

Sequence:

show sequence

CTCTTTGTGTGGTGCCCAGATAGGGGAGCGGAGGTGGCGGCGGCGGCGGTAGCGGTGGCCTTGG
TTGTCTTCCAGTCTCCTCGGCTCGCCCTTTAGCCGGCACCGCTCCCCTTCCCTCCCCCTTCCTC
TCTTCCTTCCTTCCCTCCCCTTCCCTTTTTCCCTTCCCCGTCGGTGAGCGGCGGGGGTGGCTCC
AGCAACGGCTGGGCCCAAGCTGTGTAGAGGCCTTAACCAACGATAACGGCGGCGACGGCGAAAC
CTCGGAGCTCGCAGGGCGGGGGCAAGGCCCGGGCCTTGGAGATGGAGAATTCTCAGTTGTGTAA
GCTGTTCATCGGCGGCCTCAATGTGCAGACGAGTGAGTCGGGCCTGCGCGGCCACTTTGAGGCC
TTTGGGACTCTGACGGACTGCGTGGTGGTGGTGAATCCCCAGACCAAGCGCTCCCGTTGCTTTG
GCTTCGTGACCTACTCCAATGTGGAGGAGGCGGACGCCGCCATGGCCGCCTCGCCCCATGCCGT
GGACGGCAACACTGTGGAGCTGAAGCGGGCGGTGTCCCGGGAGGATTCGGCGCGGCCCGGTGCC
CACGCCAAGGTTAAGAAGCTCTTTGTCGGAGGCCTTAAAGGAGACGTGGCTGAGGGCGACCTGA
TCGAGCACTTCTCGCAGTTTGGCACCGTGGAAAAGGCCGAGATTATTGCCGACAAGCAGTCCGG
CAAGAAGCGTGGATTCGGCTTCGTGTATTTCCAGAATCACGACGCGGCAGACAAGGCCGCGGTG
GTCAAGTTCCATCCGATTCAGGGCCATCGCGTGGAGGTGAAGAAAGCAGTCCCCAAGGAGGATA
TCTACTCCGGTGGGGGTGGAGGCGGCTCCCGATCCTCCCGGGGCGGCCGAGGCGGCCGGGGGCG
CGGCGGTGGTCGAGACCAGAACGGCCTTTCCAAGGGCGGCGGCGGCGGTTACAACAGCTACGGT
GGTTACGGCGGCGGCGGAGGCGGCGGCTACAATGCCTACGGAGGCGGCGGCGGCGGTTCGTCCT
ACGGTGGGAGCGACTACGGTAACGGCTTCGGCGGCTTCGGCAGCTACAGCCAGCATCAGTCCTC
CTATGGGCCCATGAAGAGCGGCGGCGGCGGCGGCGGTGGAGGCAGTAGCTGGGGCGGTCGCAGT
AATAGTGGACCTTACAGAGGCGGCTATGGCGGTGGGGGTGGCTATGGAGGCAGCTCCTTCTAAA
AGAAAATTTAAAATGCCTGGGAGTGGCTATAGGGGTAGCTCTTTCCAACAGCCCAAGTGGGGTC
AACTCCTAAGCCCCACCCCCTCACACACACCGCCTTCCCTGTTTTGCCCTTGGGGGAGCCACTT
CTAAGGCTGCTTACCCTTGGGGGTGTTCCTCTATTTGCCTGCCACCTCTCTTGTCTCTCCCTCT
GAAGATGGACTCGGCCCCACATACACATTTTTGTGTTACAGTCATTGATGGACTCTATTTTTTT
ATTATTACTTGGACCTTGGTCGTTTTTATACTAGCAAAATGTCTTGTTTTAATTTGTGTTTTTT
GGGGGGAGGGAGGGAGTGAACTTGCTGATTCTGTAGCAAAACCTGGGTGGGGGTTGGGGTGGGG
GGTAGTTTACTTTGTTGTAAGGACTTGATAACCTGGCTACAGCGTTTTCTATGAAATCTACTTG
GATCCCATGCCTGAAATTTGGAAGCATATGTACAAAAATCATTTTTACGTTTTATTTTTAATAA
ATCATTGTGTTTGACCGTACATGTCTAACATTTTTTTTCTAGGATCCATTCCGTACCGTTTTTT
AAGGGATATTTGTTTAAGACTTTACGTGTTAATTCTTTATTCTTGATGTGTACTTAGAGAAACT
TAAGAGGTCCTGTGGTTTTTTTCCCCTCTCCTGTTGCCCTGCTAGTTGCGTGTTGAATTATATC
CCTTACAGGCAAAACTTTTGAAGTGGTGGATGTGGCTTTTTAAACTCTTAAGTTTCTGTGCATC
CATCTCTTGTACTAAGCGAATTGTTTATCATCTTGACATGGTTGGTCATTTCTATGACAATTTA
CTTCAAACTGTGTACTGTGTAGTTCTATATAGTTTGTGTTAAGCATGTCATTCATATAAACTGT
TTAAAATTTTTCAGATGGCCTAGTTTCATCCCTCTTACTGGTTTGTCTGTAATGAATGGTTAAA
AATAAGGGTTATATTTTACCCTCAAATGCGTTTTTGTACTTTCAGAGCAGGTTTAAACGTTTTT
TTTTTTTTTTTCCTATATCCGAACTGTTGGCCTCATGGAAATCCCTTTCCCGATCTTTGTAGCA
CCATCTACTGGCAGAATGGCAGAGTAGCTGCGAAACAATTTGTTTAAAAACTTGCTTAAGACAA
TTGCATCAGATTTGGAAGTTTTGCCATCAAAATTCTTTGCAGAATTGGAAGTTAACACATTTGC
TTGTAACTGAGATGGGCTTCACAGGAATGTAGTTGCCAGTTCATATCACAATAGCCCTTTCTAT
ATGAGGTTTGAAAATGTAAACTGCTATGCATAGCTTGGGCAATAGCCCTAAATTGCTATGACAA
CTAATGAACCAGCTACGTATACTGGTATTTTAGGTGCAAGTTGTAAAGCAAAATATCTGTGTAT
TCTGCTTGGTTAACAAATGTATATTTGTAGCCCTTTCCTGCAATAGCATTCAAGTTGTTGTTTA
TAAGAGAAGAACAAAAGTGATAATAGGTGAAAATTGCCTTTCTGGATAGAAATAGAGAATAGCA
ACGTTTATGGATATCACAAATAAAGAATTCAATTCTTTACATGATTGAGTGAGAGTATGTATAA
CCTGGTGGGTGGGTTCAGAGTACCTTTTAATCTAGTATGCTTAACTTGATGTTAATATTTAACT
TAAATATTTGACTTACATGTTGACGTTGAAGGCTCAAAGCTATACTAAGAAGCTTTCTGAAAGA
TTGGGCTTTAAAATAAAATAATATTTTAATATTGAACCATTTTTTAACTTCTTGTCACTGTTCA
ATTCCTAAGGTCTAGTTCTTGCCAGTTTTTTTTTTTTTTTTCCTGATTGGCAGGGCTTTTAAAG
AAGTAAGAAGAAAGGTTAAGATTATTAGGCTAGGTTATAGCTGCTCAGTAGTCATTTTGACAAA
GGGTAGCGGATGGTTGGTACAAATAGTGTTATATCCTCTATGACAAACGGGGTGGATGTTTTTA
CACATTGAGGTAATACATAGTCAAATCCTTTGCTCTCAAATAGTTGTACACTTTCCATACATTT
CTGTCTTATTTTTTAATTCTAGTGATACACAAATTACATGTGGGCTACTTCATTTGGTAATTTG
GTCCAGCTTTTTGGTGGCTGTAGAGTGGCCTCTAGGATACAGAAAATGATTCTCTGAAATTTTT
CGTTGTAATTGTTAAATACTACTCTGCTTGACTTACTCAGTTTTGGTGGGAAGATCTGGGTCAA
TTGGAATAGTACACCTTTCTCAGGGTTTTCAGTTTAATAAGGTTGTCATATTATTCCCAACATG
GGAATATAGTGGCTTCTAAAGTTTGCAAATGAATTATGTAAAAGGATTTTCTGTGTATTAGGAA
GGCAACCTGTTCTGTTCATGGTATATTAACACTTCATTGTCATGTGTCTACCCTTAAAATTGCT
ATTTGTAGTGAAGAAAAAAGCATAGTGGTATTTAGTCACTTCTGGGTTCCTCTTGTCAGTTTAT
ATGCAAACATTTTGGCATGTGGGACTTGGGGAGGAGGGACAATTGGTTGTATGTTTTGACCACT
TCCACCTATGAAAATTATCTGAACATTATTCAGATTTAAGAGTTCATGGGAGCAGGTGGTACAG
AACCTAGTGTTGAATATAATTTTTGTGCCATGCTTGAATGTATTTTGACGGATTAGCAAAATAA
AAGTGAACCTCCTATTTTTCATCTTAATGTGAAGATCTTTGGCATTTACATTCTTTTAAAAGTA
TAAATTCAGTAGTCATTAGTTGAAAGTGGTTTGAAAGGCTGTTAGAGATGATACAGGTTGAGTA
TTCCTTATCTGAAATTCTTGGGCCCAGAAGTGTTTTGAGTTTTAGATTTTTTTCAATTTTTGAA
TATTTCCATTATGTTTACCAGCTGAGCAGCTCTCATACAAAAATGTAAAATCCAAACTGCTTCA
ATGAGCATTTCCTTTGAATGTCATGTCTGCACTCAAAAAATTTCGGATTTTGGAGCATTTTAGA
TTTTTTGATTGGAATATCTGTAGTGTTTTTCAGGTCATTTAAAAAGCTCTCATTGGTACTGATT
TACTGTATCCAAAAAAAAGCCTGCAAGTGGTTAAGGTTCACAGTGATAACTATCAAATCAGAAT
GACTATACTGATTGTACCCATTCATCCATTTTTAACTTAGTGATTTGGAACGTTTCATATTCAA
ATCTAATTTTCATAATTTTTAAGTAAACCTAAAAGATTGAGGATACTTGAGAAATTTGCATTTA
TGATTTCCTTCAAAACCAGAAGTGATGGTATCAGTTATTGGATTTGTAAACTTAGTTTACCTTT
TAAGTGTGCTTAAGTTTTGAGAGTTTGCATTTTAGGTTAAATTTTGTCTGCCCGCGTCTGCTGA
TTGCAGATAGGCATTTGGATGTTGGATTTGGAGCAGAACTGCATCTAGACTACACGGATTTTAC
CCAAAAAGACAGCACTTGCACTTAGGCTAAGTGTCTTTCTCCATCGTAACCAATTTATTGAATC
ACTTTAAGAGTGATCATTGGGGAAATTTTCCTCCTCAGCCTTATTTTGGCCTTTTGAAACAGCA
ACAAAGACTGCCTAGTCAAATAACTCCTTAGCTGTCCTGCTTTTGAGTGAACTTCATATTTGCC
TTGAATGAGAATTTAAATGTTACAAGGTAAAACATTTATTATAAAAAGATATTTGAAAGCTGCT
ATTTAAAAAGGAATTCCAAAGTAGGAAGACTAGAAGGGCAATTCTCTATTTTCCACCTATTTTT
TTTACTTTGATTTGAAGCCAGATGATTTGAACCTTCAGAGAGGGAAAGGATTCAGGAAGACACC
TTTGGTAGTTATTCTTAACTGTTTCCTTCTCTATTCAGGCAGGCTTTCTTTGTCTCTTTAATTC
TTTTACCACTTTGTATGGTTTACTTAAAAAATCTATCTGAAATAGCTATCATTTCCTGCTATAA
AGTTCTCAAGTGTAAACTTTTGCCATTTAAACAGTGTGCTTATTTCCCAGTGTTTACCGTCAAT
TTCATTGGGTGTTAGGCACCTTTGTGTAAGACAGTTCTATAATGTGGAGGTACACAGCAGTGAG
ACAAACATGGTTGCTGTCTTCATATACCTTGCGTTCTGGTTGGAATTCAATTTATTTTGAAATG
GGAATTCAATTTATTTTGAGATGATGCATCTTTTCCTTTACAGCATTGTGTCACAATCTCATAT
TGTTCACACCATCAAAATTGGAGTTAGCTCCATTGTCATTGAATGTACATTCTCTGATGAAAAT
TAAGACTCTTTTCTCCTTAATTGATTACTTTTTAGAAATCAAAGGTGTATTTTGTCTTTGATGC
TTACGTTGCAAATGTAATTTGCTTCATAGTGGGTATCTGATTTAATATTTCATAGCCCTTAAGG
ACGTAAATTTGGGCATCCAATAGACCAAATTCTGTTCCTGACACAGTCACTTTCTAGCACTGCG
ACCTTGGACAAACTGGCCCGAGCCTCACTTGCCTTATTTGTAAAAAAATAGGCTATGGTAATAC
CTGCTACATAGGATTGTTGGGCAGATTCAGTGAAAGAATGCATATAAAGAAGGGCTTACTGTAG
TCTCTGGTACACAGTAATTTTACTATATGGCCCCTAATGAAGAGGTGGGACAGACTAGCAAAAG
GCATACTTTTATATCTTAGTACCCGAGATATGCATGGTCTTTAGGCTTTGCTCTTTACTTGCTG
GGTGAGCTTCCATGTGGTAGTTCTCTAAATCACTGCTGCTTCAACTCTAGTAGGAGAGAGATGA
ATTCTGCTAGCCATCTGTAATGTTTTAAGTATTTGTTAATATTAGGAAGGTATAAATAATGTGA
GTGTTGAGGAGAGGTGACTTCAGGTAGGAAGAAGGATCAAGAGAGGCATTGTGGAGCATATAAC
ATTTAACCTTAAAAGATAGGTCTTATAGAGAAGGTGGGAGGAGAAAGAGGGCATTTTAGGTGGA
GGACAGATAGGCAGAAACATGGAGCGTATTTGGAGAAGTATGCATATTGGATGCCAAACACTAG
GTACATTTACAAATGTTCTCATTGCATCATTCAGTAACCTTCACAGATAAGGTTGCTAAATCTC
ATGCCAGAAAAGTAACTCCCAAGGACCCCCAGCTGGTGACATGGTAGAACTGAGAGTTGAATCC
AAGTTTGACCAATTCTAGTTGTTTCGCTCCTTCTACTAAGCTTCATTGACTTCCAGCTAACAAA
TGTCTAATTTGTACTAAGATAAAAGAGAGTTGTGAGAAATAAATTGAGAAAATGAAGTTGGAAC
CAGGTTACTGAGGTCTTTGAGTAGTAGGCTAAGGAGTTTGGACTTAGGGTAGGCAGTAAAAGTC
ATTAAAGGTTTTTGAGCAACAATAATGGTAGTGAAACTAATTCACAAAGATTAGTCCAGTAGCA
CTGAGTAACATAAATGGCAGTGGGGGATGTTTCAAAGTGGCAAGTTTGCTAAGACAACTGATGT
TAACCAGGTAAGAGAATGAGAGCATGAACAAAGAGCAATGGAAATAGACTGACAAAGAAGTTGA
GGTAAGTTGTGAAAGCATAATTGACAAATATTTGGATATATGAAGAATGAGGAAGAGAGAGTAG
ATTAATCAAAATTACTGTGTGAGAGGATGGTGATGCCACTGGTAATAGGAAGAGAAGATTTAGA
GGGAAGATTTGGACATAGTTGAAGATGCTGGTAGCACATTGAAGCATTGTGTCTTGCGCATATA
GCTTTACAAAATGGCCATTGTGCTGGATATTCTTTTTGCCCTTCCTGATCTATTTTCCATCTTT
ATCTCTCTTGTTCTGTGTTCCTGGGAGGCTGACAAATAAAGAACTGCATACTCTCTTTTCTGGC
TTTATTCATGGTGGGTTTGGACAGTGATAGAAAAGTGAGGCTGAAATATTTGCTCCTTCTCTTT
CTCATATACTTAGCAAGAGATTGTGAGTGGCCACAGCTCTGCTCCAGTGGCCCTCTTATAGCTC
TAGGTCTTTTCTGGCTTCTCGTAACTGTCTCCTATTGCTAGATTCTCTAGTCCCAAGAAGGTTC
AAACCTTGTTGATTTGCCTTAACTGTGCCCATACCCTTGTAAATAGTTCCTTTTATTAAAACTC
TTCAATAACTGAATATACTGTGGTCATCTCTTCAGTGAAATTAAAAAAAAAAACTTCTTTCACA
TTTTCTTATGACTTGATCTTCCCACACCACCAAACGTGAAGATCTAGCTATTTGCACTAGGTTA
CTATCCCTAAATTCAGTGCCTCCCTGTTTCTTAGTATGTCAAGTTAAAATTTGTTACTCTTCTG
CTGGGTGATTGTGCTGGAAATACAGAAGAAAAAGACAAAAATCCCTGCCCTCAAAGAGCTTATA
TTTTACTGGGGAGAGACAGGCAATAAGACATAATCAATTATATGGTATGTTAGAAGATGAGAAG
TATAGAAAAAATTAGGGTGAGGAATGGCGATTGTTGCAAGGGATGTTTGTGAGGATAGCATACT
TTAAAATAGGTGGTATGGGTAGGTCTCTCAGAAAGTGACATTTGAGCAAAGACTTGAAGGAAAT
GTGGGAGTGAGCAATATAGGTATGGGAAGAGCATTCTAGGTAGAGGATTAGGAAGAGCAAAAGC
CCTGAAGCAGGACTGTGTCTGGCCTCTGAAGAAATGCAAATTGTTCAGGGTTGTTGGACCTGAA
GGAAGAGGAGGAAAGGAATAATGAGGCCAGAGGGGCCAGATCATGTAGGGATTTGTAGGTTGTT
GTAAGGATTTTGGTTTTCACTAAATGAATGGTGAACCATTTCAGTTTTGAGCAGAGGAGTTCCA
TGATCTGATTTGAATTTTAAAAGATGTGTTTCCCAAAATTCCTATTCCTTTCATACAGCTGCTT
TCAATGAAGGTTTATAAGGAAAGCAATCAGAACTACTTGGATAAGGTATAAGTGATCCACAATC
TTTTCAACTCTACCATAGGTATCTACATATATATGTTGAGAGATGCTGCTTTTTGGCCAAAATG
AATCTTGAATTGGGGGTGTGCAGAAAAAGTTATATCTGGCCTGAGGCTGGTATCTTTTAGAGTG
GCCTACTTGCATGGTTGGCCCTTATCTGAACACGTGGATTTAGGGGTATTCTCACTGTTCACTA
ATAAAGGTGGTTCACTGTACCTAGACTGTTCAAACAAGATGATTTATGCTAAACACCTGCTTTC
CTTCTGGGAGTATGGAATTTTGGTACATGCCAGGTAAAGGATGTCTATATGACCAAACTCCCAA
TGAAAACCTTGCATACTGAGTCCCTAGGCAGAAACATCCCTCGTATAAAAATGTGCTCTGTGTG
AATCTTCATGGGAGGGAGAGATCCTAAAGAAGCCTGCACATGGATTCCTCCAGATTCTGCTTAT
GTCTTTTTCCTGTATGATCCAACTGTGTACACTTACTGTGTCACTGTAATAAACTTTAGCCATG
AGTACGATA

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Protein Sequences


Protein RefSeqs	NP_006796	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA65094	(Get FASTA)	NCBI Sequence Viewer
	AAH01008	(Get FASTA)	NCBI Sequence Viewer
	AAH07271	(Get FASTA)	NCBI Sequence Viewer
	AAH09284	(Get FASTA)	NCBI Sequence Viewer
	AAH11972	(Get FASTA)	NCBI Sequence Viewer
	AAH12980	(Get FASTA)	NCBI Sequence Viewer
	AAH18949	(Get FASTA)	NCBI Sequence Viewer
	AAH19271	(Get FASTA)	NCBI Sequence Viewer
	AAH28976	(Get FASTA)	NCBI Sequence Viewer
	AAH30249	(Get FASTA)	NCBI Sequence Viewer
	CAG33267	(Get FASTA)	NCBI Sequence Viewer
	CBF67657	(Get FASTA)	NCBI Sequence Viewer
	CBU92531	(Get FASTA)	NCBI Sequence Viewer
	EAW62182	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000316042
	ENSP00000316042.4
GenBank Protein	Q13151	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_006796 ⟸ NM_006805

- UniProtKB:

Q13151 (UniProtKB/Swiss-Prot), Q6IB18 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAA
MAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAE
IIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSR
GGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFG
SYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGGSSF

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Ensembl Acc Id:

ENSP00000316042 ⟸ ENST00000314940

Ensembl Acc Id:

ENSP00000516066 ⟸ ENST00000705031

Protein Domains

RRM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q13151-F1-model_v2	AlphaFold	Q13151	1-305	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:5030	AgrOrtholog
COSMIC	HNRNPA0	COSMIC
Ensembl Genes	ENSG00000177733	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000314940	ENTREZGENE
	ENST00000314940.7	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.70.330	UniProtKB/Swiss-Prot
GTEx	ENSG00000177733	GTEx
HGNC ID	HGNC:5030	ENTREZGENE
Human Proteome Map	HNRNPA0	Human Proteome Map
InterPro	hnRNPA0_RRM1	UniProtKB/Swiss-Prot
	Nucleotide-bd_a/b_plait_sf	UniProtKB/Swiss-Prot
	RBD_domain_sf	UniProtKB/Swiss-Prot
	RRM_dom	UniProtKB/Swiss-Prot
KEGG Report	hsa:10949	UniProtKB/Swiss-Prot
NCBI Gene	10949	ENTREZGENE
OMIM	609409	OMIM
PANTHER	HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0,-LIKE	UniProtKB/Swiss-Prot
	HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN	UniProtKB/Swiss-Prot
Pfam	RRM_1	UniProtKB/Swiss-Prot
PharmGKB	PA162391106	PharmGKB
PROSITE	RRM	UniProtKB/Swiss-Prot
SMART	RRM	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54928	UniProtKB/Swiss-Prot
UniProt	Q13151	ENTREZGENE
	Q6IB18	ENTREZGENE
	ROA0_HUMAN	UniProtKB/Swiss-Prot
UniProt Secondary	Q6IB18	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

RGD Manual Annotations