Symbol:
Golga4
Name:
golgin A4
Description:
Predicted to have GTPase binding activity. Predicted to be involved in Golgi to plasma membrane protein transport and positive regulation of axon extension. Predicted to localize to the Golgi apparatus and nucleoplasm. Orthologous to human GOLGA4 (golgin A4); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; cisplatin.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
golgi autoantigen, golgin subfamily a, 4; Golgin subfamily A member 4; LOC501069; similar to golgi autoantigen golgin subtype a4; tGolgin-1
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
GOLGA4 (golgin A4) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Golga4 (golgi autoantigen, golgin subfamily a, 4) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Golga4 (golgin A4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
GOLGA4 (golgin A4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
GOLGA4 (golgin A4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Golga4 (golgin A4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
GOLGA4 (golgin A4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
GOLGA4 (golgin A4)
Alliance
DIOPT (Ensembl Compara, HGNC, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER)
Mus musculus (house mouse):
Golga4 (golgi autoantigen, golgin subfamily a, 4)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER)
Danio rerio (zebrafish):
golga4 (golgin A4)
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER)
Drosophila melanogaster (fruit fly):
Golgin245
Alliance
DIOPT (Ensembl Compara, InParanoid, OrthoFinder, OrthoInspector, PANTHER)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 8 127,171,221 - 127,248,938 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 127,171,537 - 127,248,538 (+) Ensembl Rnor_5.0 8 126,393,530 - 126,471,244 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 8 123,404,540 - 123,504,104 (+) NCBI RGSC3.4 rn4 RGSC3.4 Celera 8 117,393,586 - 117,470,254 (+) NCBI Celera Cytogenetic Map 8 q32 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
(S)-nicotine multiple interactions ISO RGD:1352947 6480464 alpha-cobratoxin inhibits the reaction [Nicotine results in increased expression of GOLGA4 mRNA], Tubocurarine inhibits the reaction [Nicotine results in increased expression of GOLGA4 mRNA] CTD PMID:16949557 (S)-nicotine increases expression ISO RGD:1352947 6480464 Nicotine results in increased expression of GOLGA4 mRNA CTD PMID:16949557 1-nitropyrene increases expression ISO RGD:1352947 6480464 1-nitropyrene results in increased expression of GOLGA4 mRNA CTD PMID:19041380 17alpha-ethynylestradiol multiple interactions ISO RGD:1557150 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GOLGA4 mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of GOLGA4 mRNA CTD PMID:29097150 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:1352947 6480464 Dihydrotestosterone results in increased expression of GOLGA4 mRNA CTD PMID:29581250 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1557150 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GOLGA4 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1557150 6480464 Tetrachlorodibenzodioxin affects the expression of GOLGA4 mRNA CTD PMID:21570461 4,4'-diaminodiphenylmethane increases expression ISO RGD:1557150 6480464 4, 4'-diaminodiphenylmethane results in increased expression of GOLGA4 mRNA CTD PMID:18648102 aflatoxin B1 increases expression ISO RGD:1557150 6480464 Aflatoxin B1 results in increased expression of GOLGA4 mRNA CTD PMID:19770486 aflatoxin M1 decreases expression ISO RGD:1352947 6480464 Aflatoxin M1 results in decreased expression of GOLGA4 mRNA CTD PMID:30928695 arsane decreases expression ISO RGD:1352947 6480464 Arsenic results in decreased expression of GOLGA4 mRNA CTD PMID:16835338 arsane affects methylation ISO RGD:1352947 6480464 Arsenic affects the methylation of GOLGA4 gene CTD PMID:25304211 arsane decreases expression ISO RGD:1557150 6480464 Arsenic results in decreased expression of GOLGA4 mRNA CTD PMID:19654921 arsenic atom decreases expression ISO RGD:1352947 6480464 Arsenic results in decreased expression of GOLGA4 mRNA CTD PMID:16835338 arsenic atom affects methylation ISO RGD:1352947 6480464 Arsenic affects the methylation of GOLGA4 gene CTD PMID:25304211 arsenic atom decreases expression ISO RGD:1557150 6480464 Arsenic results in decreased expression of GOLGA4 mRNA CTD PMID:19654921 benzo[a]pyrene increases expression ISO RGD:1557150 6480464 Benzo(a)pyrene results in increased expression of GOLGA4 mRNA CTD PMID:22228805 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1352947 6480464 7 more ... CTD PMID:19150397 , PMID:26238291 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GOLGA4 mRNA CTD PMID:25181051 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GOLGA4 gene CTD PMID:28505145 cadmium dichloride decreases expression ISO RGD:1557150 6480464 Cadmium Chloride results in decreased expression of GOLGA4 mRNA CTD PMID:24982889 carbon nanotube decreases expression ISO RGD:1557150 6480464 Nanotubes, Carbon analog results in decreased expression of GOLGA4 mRNA, Nanotubes, Carbon results in decreased expression of GOLGA4 mRNA CTD PMID:25554681 carmustine increases expression ISO RGD:1352947 6480464 Carmustine results in increased expression of GOLGA4 mRNA CTD PMID:15980968 chromium(6+) affects expression ISO RGD:1557150 6480464 chromium hexavalent ion affects the expression of GOLGA4 mRNA CTD PMID:28472532 cisplatin decreases phosphorylation ISO RGD:1557150 6480464 Cisplatin results in decreased phosphorylation of GOLGA4 protein CTD PMID:22006019 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of GOLGA4 mRNA CTD PMID:22023808 clorgyline increases expression ISO RGD:1352947 6480464 Clorgyline results in increased expression of GOLGA4 mRNA CTD PMID:19691856 copper(II) sulfate decreases expression ISO RGD:1352947 6480464 Copper Sulfate results in decreased expression of GOLGA4 mRNA CTD PMID:19549813 cyclosporin A increases expression ISO RGD:1352947 6480464 Cyclosporine results in increased expression of GOLGA4 mRNA CTD PMID:20106945 , PMID:25562108 dorsomorphin multiple interactions ISO RGD:1352947 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GOLGA4 mRNA CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1557150 6480464 Doxorubicin results in decreased expression of GOLGA4 mRNA CTD PMID:19277126 formaldehyde increases expression ISO RGD:1352947 6480464 Formaldehyde results in increased expression of GOLGA4 mRNA CTD PMID:23649840 hexadecanoic acid decreases phosphorylation ISO RGD:1352947 6480464 Palmitic Acid results in decreased phosphorylation of GOLGA4 protein CTD PMID:28073184 hydrogen peroxide decreases expression ISO RGD:1352947 6480464 Hydrogen Peroxide results in decreased expression of GOLGA4 mRNA CTD PMID:18951874 lead(0) affects splicing ISO RGD:1352947 6480464 Lead affects the splicing of GOLGA4 mRNA CTD PMID:28903495 lead(2+) affects splicing ISO RGD:1352947 6480464 Lead affects the splicing of GOLGA4 mRNA CTD PMID:28903495 linsidomine increases oxidation EXP 6480464 linsidomine results in increased oxidation of GOLGA4 protein CTD PMID:28086193 Mecamylamine increases expression ISO RGD:1352947 6480464 Mecamylamine results in increased expression of GOLGA4 mRNA CTD PMID:16949557 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of GOLGA4 mRNA CTD PMID:30467583 methyl methanesulfonate increases expression ISO RGD:1352947 6480464 Methyl Methanesulfonate results in increased expression of GOLGA4 mRNA CTD PMID:23649840 methylmercury chloride decreases expression ISO RGD:1352947 6480464 methylmercuric chloride results in decreased expression of GOLGA4 mRNA CTD PMID:28001369 nicotine multiple interactions ISO RGD:1352947 6480464 alpha-cobratoxin inhibits the reaction [Nicotine results in increased expression of GOLGA4 mRNA], Tubocurarine inhibits the reaction [Nicotine results in increased expression of GOLGA4 mRNA] CTD PMID:16949557 nicotine increases expression ISO RGD:1352947 6480464 Nicotine results in increased expression of GOLGA4 mRNA CTD PMID:16949557 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of GOLGA4 mRNA CTD PMID:25729387 paracetamol affects expression ISO RGD:1557150 6480464 Acetaminophen affects the expression of GOLGA4 mRNA CTD PMID:17562736 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1352947 6480464 perfluorooctane sulfonic acid results in decreased expression of GOLGA4 mRNA CTD PMID:27153767 phenobarbital decreases expression ISO RGD:1557150 6480464 Phenobarbital results in decreased expression of GOLGA4 mRNA CTD PMID:23091169 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of GOLGA4 mRNA CTD PMID:15215175 rotenone increases expression EXP 6480464 Rotenone results in increased expression of GOLGA4 mRNA CTD PMID:19013527 SB 431542 multiple interactions ISO RGD:1352947 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GOLGA4 mRNA CTD PMID:27188386 sodium arsenate increases expression ISO RGD:1557150 6480464 sodium arsenate results in increased expression of GOLGA4 mRNA CTD PMID:21795629 sodium arsenite affects methylation ISO RGD:1352947 6480464 sodium arsenite affects the methylation of GOLGA4 gene CTD PMID:28589171 succimer multiple interactions ISO RGD:1557150 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of GOLGA4 mRNA CTD PMID:21641980 testosterone enanthate affects expression ISO RGD:1352947 6480464 testosterone enanthate affects the expression of GOLGA4 mRNA CTD PMID:17440010 titanium dioxide increases expression ISO RGD:1557150 6480464 titanium dioxide results in increased expression of GOLGA4 mRNA CTD PMID:23131501 toluene increases expression ISO RGD:1352947 6480464 Toluene results in increased expression of GOLGA4 mRNA CTD PMID:28245982 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of GOLGA4 mRNA CTD PMID:25729387 trichostatin A increases expression ISO RGD:1352947 6480464 trichostatin A results in increased expression of GOLGA4 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:1352947 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GOLGA4 mRNA CTD PMID:27188386 troglitazone decreases expression ISO RGD:1557150 6480464 troglitazone results in decreased expression of GOLGA4 mRNA CTD PMID:28973697 trovafloxacin multiple interactions ISO RGD:1557150 6480464 [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of GOLGA4 mRNA CTD PMID:18930950 tubocurarine decreases expression ISO RGD:1352947 6480464 Tubocurarine results in decreased expression of GOLGA4 mRNA CTD PMID:16949557 tubocurarine multiple interactions ISO RGD:1352947 6480464 Tubocurarine inhibits the reaction [Nicotine results in increased expression of GOLGA4 mRNA] CTD PMID:16949557 tunicamycin increases expression ISO RGD:1352947 6480464 Tunicamycin results in increased expression of GOLGA4 mRNA CTD PMID:22378314 
Gene-Chemical Interaction Annotations
