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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1560158
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ndufaf2
Name: NADH:ubiquinone oxidoreductase complex assembly factor 2
Acc ID: CHEBI:9381
Term: T-2 toxin
Definition: A trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals.
Chemical ID: MESH:D013605
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ndufaf2increases expressionEXP 6480464CTDT-2 Toxin results in increased expression of NDUFAF2 mRNAPMID:29870751 PMID:36863559
Ndufaf2multiple interactionsEXP 6480464CTDGABPA promotes the reaction [T-2 Toxin results in increased expression of NDUFAF2 mRNA]; T-2 Toxin promotes the reaction [GABPA protein binds to NDUFAF2]PMID:36863559
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