Utp14a (UTP14A small subunit processome component) - Rat Genome Database

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Gene: Utp14a (UTP14A small subunit processome component) Rattus norvegicus
Analyze
Symbol: Utp14a
Name: UTP14A small subunit processome component
RGD ID: 1359313
Description: Predicted to be involved in rRNA processing. Predicted to be located in cytosol. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human UTP14A (UTP14A small subunit processome component) and UTP14C (UTP14C small subunit processome component); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC317579; similar to KIAA0266 gene product; U3 small nucleolar RNA-associated protein 14 homolog A; UTP14, U3 small nucleolar ribonucleoprotein, homolog A; UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast); UTP14A small subunit (SSU) processome component
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X132,317,163 - 132,342,524 (+)NCBIGRCr8
mRatBN7.2X127,439,282 - 127,464,634 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX127,439,268 - 127,464,633 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX129,565,072 - 129,590,258 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X133,135,896 - 133,161,183 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X130,662,229 - 130,687,417 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X135,092,123 - 135,117,409 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX135,092,040 - 135,117,455 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X135,163,467 - 135,189,080 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X134,625,490 - 134,653,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X134,718,635 - 134,726,873 (+)NCBI
CeleraX126,389,666 - 126,414,950 (+)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Utp14a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X132,317,163 - 132,342,524 (+)NCBIGRCr8
mRatBN7.2X127,439,282 - 127,464,634 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX127,439,268 - 127,464,633 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX129,565,072 - 129,590,258 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X133,135,896 - 133,161,183 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X130,662,229 - 130,687,417 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X135,092,123 - 135,117,409 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX135,092,040 - 135,117,455 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X135,163,467 - 135,189,080 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X134,625,490 - 134,653,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X134,718,635 - 134,726,873 (+)NCBI
CeleraX126,389,666 - 126,414,950 (+)NCBICelera
Cytogenetic MapXq36NCBI
UTP14A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X129,906,164 - 129,929,752 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX129,906,121 - 129,929,761 (+)EnsemblGRCh38hg38GRCh38
GRCh37X129,040,140 - 129,063,728 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X128,867,840 - 128,891,409 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X128,765,693 - 128,789,262NCBI
CeleraX129,426,601 - 129,450,242 (+)NCBICelera
Cytogenetic MapXq26.1NCBI
HuRefX118,440,548 - 118,464,036 (+)NCBIHuRef
CHM1_1X128,951,416 - 128,975,066 (+)NCBICHM1_1
T2T-CHM13v2.0X128,224,954 - 128,248,543 (+)NCBIT2T-CHM13v2.0
Utp14a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X47,345,811 - 47,371,326 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX47,345,739 - 47,371,330 (+)EnsemblGRCm39 Ensembl
GRCm38X48,256,934 - 48,282,450 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX48,256,862 - 48,282,453 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X45,610,111 - 45,635,626 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X44,501,561 - 44,527,076 (+)NCBIMGSCv36mm8
CeleraX35,759,229 - 35,784,130 (+)NCBICelera
Cytogenetic MapXA4NCBI
cM MapX25.59NCBI
Utp14a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554735,100,924 - 5,125,107 (-)NCBIChiLan1.0ChiLan1.0
UTP14A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X129,325,592 - 129,350,370 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X129,328,589 - 129,353,985 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X119,032,503 - 119,056,780 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X129,330,213 - 129,353,407 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX129,330,213 - 129,353,407 (+)Ensemblpanpan1.1panPan2
UTP14A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X101,099,187 - 101,117,388 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX87,273,172 - 87,291,449 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X102,950,950 - 102,969,225 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X100,369,031 - 100,387,309 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X102,215,205 - 102,233,479 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X101,993,136 - 102,011,413 (+)NCBIUU_Cfam_GSD_1.0
Utp14a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X99,319,782 - 99,340,893 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364791,646,600 - 1,667,677 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UTP14A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X106,479,028 - 106,500,389 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X122,248,012 - 122,269,352 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UTP14A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X105,168,193 - 105,192,226 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX105,168,278 - 105,192,082 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606542,586,513 - 42,611,052 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Utp14a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247979,142,925 - 9,167,141 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Utp14a
68 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:37
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000048022
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat

Markers in Region
DXRat118  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X127,438,586 - 127,438,793 (+)MAPPERmRatBN7.2
Rnor_6.0X135,091,363 - 135,091,569NCBIRnor6.0
Rnor_5.0X135,162,707 - 135,162,913UniSTSRnor5.0
RGSC_v3.4X134,624,729 - 134,624,936RGDRGSC3.4
RGSC_v3.4X134,624,730 - 134,624,936UniSTSRGSC3.4
RGSC_v3.1X134,698,162 - 134,698,369RGD
CeleraX126,388,906 - 126,389,112UniSTS
FHH x ACI MapX39.06RGD
FHH x ACI MapX39.06UniSTS
Cytogenetic MapXq35UniSTS
RH131042  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X127,464,353 - 127,464,556 (+)MAPPERmRatBN7.2
Rnor_6.0X135,117,129 - 135,117,331NCBIRnor6.0
Rnor_5.0X135,188,800 - 135,189,002UniSTSRnor5.0
RGSC_v3.4X134,653,161 - 134,653,363UniSTSRGSC3.4
CeleraX126,414,670 - 126,414,872UniSTS
RH 3.4 MapX925.0UniSTS
Cytogenetic MapXq35UniSTS
RH133988  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X127,439,770 - 127,439,987 (+)MAPPERmRatBN7.2
Rnor_6.0X135,092,547 - 135,092,763NCBIRnor6.0
Rnor_5.0X135,163,891 - 135,164,107UniSTSRnor5.0
RGSC_v3.4X134,625,914 - 134,626,130UniSTSRGSC3.4
CeleraX126,390,090 - 126,390,306UniSTS
RH 3.4 MapX923.6UniSTS
Cytogenetic MapXq35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000048022   ⟹   ENSRNOP00000051553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX127,439,268 - 127,464,633 (+)Ensembl
Rnor_6.0 EnsemblX135,092,040 - 135,117,455 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096225   ⟹   ENSRNOP00000088620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX127,439,339 - 127,464,632 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106554   ⟹   ENSRNOP00000076502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX127,440,038 - 127,464,633 (+)Ensembl
RefSeq Acc Id: NM_001014113   ⟹   NP_001014135
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X132,317,240 - 132,342,524 (+)NCBI
mRatBN7.2X127,439,347 - 127,464,634 (+)NCBI
Rnor_6.0X135,092,123 - 135,117,409 (+)NCBI
Rnor_5.0X135,163,467 - 135,189,080 (+)NCBI
RGSC_v3.4X134,625,490 - 134,653,441 (+)RGD
CeleraX126,389,666 - 126,414,950 (+)RGD
Sequence:
RefSeq Acc Id: XM_039099849   ⟹   XP_038955777
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X132,333,505 - 132,342,524 (+)NCBI
mRatBN7.2X127,455,597 - 127,464,609 (+)NCBI
RefSeq Acc Id: XM_039099850   ⟹   XP_038955778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X132,317,163 - 132,338,683 (+)NCBI
mRatBN7.2X127,439,282 - 127,460,846 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001014135 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955777 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955778 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88326 (Get FASTA)   NCBI Sequence Viewer  
  AAH99799 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000051553.5
  ENSRNOP00000076502.1
  ENSRNOP00000088620.1
RefSeq Acc Id: NP_001014135   ⟸   NM_001014113
- UniProtKB: Q499R2 (UniProtKB/TrEMBL),   A0A8I5ZJ69 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000051553   ⟸   ENSRNOT00000048022
RefSeq Acc Id: XP_038955778   ⟸   XM_039099850
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038955777   ⟸   XM_039099849
- Peptide Label: isoform X2
- UniProtKB: A6JMP9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088620   ⟸   ENSRNOT00000096225
Ensembl Acc Id: ENSRNOP00000076502   ⟸   ENSRNOT00000106554

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZY2-F1-model_v2 AlphaFold D3ZZY2 1-803 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702011
Promoter ID:EPDNEW_R12535
Type:initiation region
Name:Utp14a_1
Description:UTP14A small subunit processome component
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X135,092,112 - 135,092,172EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359313 AgrOrtholog
BioCyc Gene G2FUF-1135 BioCyc
Ensembl Genes ENSRNOG00000005012 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048022.6 UniProtKB/TrEMBL
  ENSRNOT00000096225.1 UniProtKB/TrEMBL
  ENSRNOT00000106554.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7365084 IMAGE-MGC_LOAD
  IMAGE:7936638 IMAGE-MGC_LOAD
InterPro SSU_processome_Utp14 UniProtKB/TrEMBL
KEGG Report rno:317579 UniProtKB/TrEMBL
MGC_CLONE MGC:109573 IMAGE-MGC_LOAD
  MGC:124850 IMAGE-MGC_LOAD
NCBI Gene 317579 ENTREZGENE
PANTHER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A UniProtKB/TrEMBL
  Utp14 UniProtKB/TrEMBL
Pfam Utp14 UniProtKB/TrEMBL
PhenoGen Utp14a PhenoGen
RatGTEx ENSRNOG00000005012 RatGTEx
UniProt A0A8I5ZJ69 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AJ81_RAT UniProtKB/TrEMBL
  A6JMP9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZY2_RAT UniProtKB/TrEMBL
  Q499R2 ENTREZGENE, UniProtKB/TrEMBL
  Q5M811_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Utp14a  UTP14A small subunit processome component  Utp14a  UTP14A small subunit (SSU) processome component  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-10-28 Utp14a  UTP14A small subunit (SSU) processome component  Utp14a  UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Utp14a  UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)  LOC317579  similar to KIAA0266 gene product  Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC317579  similar to KIAA0266 gene product      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference