Gene: Setdb1 (SET domain, bifurcated 1) Rattus norvegicus
Symbol: Setdb1
Name: SET domain, bifurcated 1
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); promoter-specific chromatin binding (ortholog); INVOLVED IN response to ethanol; response to vitamin; bone development (ortholog); PARTICIPATES IN homocysteine metabolic pathway; methionine cycle/metabolic pathway; Wnt signaling, non-canonical pathway; ASSOCIATED WITH Autistic Disorder (ortholog); glioma (ortholog); Huntington's Disease (ortholog); FOUND IN cytosol (ortholog); intracellular membrane-bounded organelle (ortholog); nuclear chromatin (ortholog); INTERACTS WITH bisphenol A; glyphosate; T-2 Toxin
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: histone-lysine N-methyltransferase SETDB1; LOC310668; LOC689883; similar to Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET)
Homo sapiens (human) : SETDB1 (SET domain bifurcated 1)  HGNC  Alliance
Mus musculus (house mouse) : Setdb1 (SET domain, bifurcated 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Setdb1 (SET domain bifurcated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SETDB1 (SET domain bifurcated 1)
Canis lupus familiaris (dog) : SETDB1 (SET domain bifurcated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Setdb1 (SET domain bifurcated 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02196,495,867 - 196,527,412 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02215,994,295 - 216,025,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,232,228 - 190,264,309 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12190,195,015 - 190,227,043 (-)NCBI
Celera2175,432,236 - 175,463,195 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Setdb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308370
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE