Pi4kb (phosphatidylinositol 4-kinase beta) - Rat Genome Database

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Gene: Pi4kb (phosphatidylinositol 4-kinase beta) Rattus norvegicus
Analyze
Symbol: Pi4kb
Name: phosphatidylinositol 4-kinase beta
RGD ID: 621214
Description: Enables 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and phosphatidylinositol-mediated signaling. Predicted to act upstream of or within lysosome organization. Located in cytosol and plasma membrane. Orthologous to human PI4KB (phosphatidylinositol 4-kinase beta); PARTICIPATES IN inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: catalytic phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, catalytic, beta; phosphatidylinositol 4-kinase, catalytic, beta polypeptide; PI4K-beta; PI4Kbeta; Pik4cb; ptdIns 4-kinase beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22182,540,377 - 182,572,684 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2182,540,567 - 182,588,488 (+)Ensembl
Rnor_6.02196,139,724 - 196,172,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,139,755 - 196,171,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,634,003 - 215,666,743 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,874,613 - 189,906,640 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12189,834,020 - 189,866,048 (+)NCBI
Celera2175,082,416 - 175,114,456 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:14607934   PMID:14607979   PMID:16638749   PMID:17088255   PMID:18474610   PMID:23572552   PMID:23899475   PMID:27009356  


Genomics

Comparative Map Data
Pi4kb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22182,540,377 - 182,572,684 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2182,540,567 - 182,588,488 (+)Ensembl
Rnor_6.02196,139,724 - 196,172,055 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2196,139,755 - 196,171,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02215,634,003 - 215,666,743 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42189,874,613 - 189,906,640 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12189,834,020 - 189,866,048 (+)NCBI
Celera2175,082,416 - 175,114,456 (+)NCBICelera
Cytogenetic Map2q34NCBI
PI4KB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381151,291,797 - 151,327,715 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1151,291,797 - 151,327,715 (-)EnsemblGRCh38hg38GRCh38
GRCh371151,264,273 - 151,300,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,531,037 - 149,565,348 (-)NCBINCBI36hg18NCBI36
Build 341148,077,485 - 148,111,797NCBI
Celera1124,379,704 - 124,414,015 (-)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1122,642,216 - 122,678,133 (-)NCBIHuRef
CHM1_11152,660,019 - 152,695,935 (-)NCBICHM1_1
Pi4kb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39394,882,042 - 94,914,248 (+)NCBIGRCm39mm39
GRCm39 Ensembl394,882,042 - 94,914,154 (+)Ensembl
GRCm38394,974,731 - 95,006,937 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl394,974,731 - 95,006,843 (+)EnsemblGRCm38mm10GRCm38
MGSCv37394,778,653 - 94,810,765 (+)NCBIGRCm37mm9NCBIm37
MGSCv36395,060,140 - 95,091,993 (+)NCBImm8
Celera396,405,996 - 96,438,094 (+)NCBICelera
Cytogenetic Map3F2.1NCBI
Pi4kb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955588648,180 - 679,374 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955588648,180 - 679,374 (-)NCBIChiLan1.0ChiLan1.0
PI4KB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11130,300,844 - 130,336,320 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1130,300,844 - 130,336,311 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01126,653,794 - 126,689,690 (-)NCBIMhudiblu_PPA_v0panPan3
PI4KB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11760,359,545 - 60,386,093 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1760,360,236 - 60,384,778 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,803,028 - 59,830,272 (-)NCBI
ROS_Cfam_1.01761,375,750 - 61,403,019 (-)NCBI
ROS_Cfam_1.0 Ensembl1761,375,754 - 61,402,452 (-)Ensembl
UMICH_Zoey_3.11760,203,634 - 60,230,882 (-)NCBI
UNSW_CanFamBas_1.01760,289,810 - 60,317,042 (-)NCBI
UU_Cfam_GSD_1.01761,018,193 - 61,044,694 (-)NCBI
Pi4kb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505822,465,447 - 22,493,491 (-)NCBI
SpeTri2.0NW_0049365801,495,833 - 1,523,307 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PI4KB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl497,918,245 - 97,949,924 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1497,918,234 - 97,949,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24107,119,069 - 107,150,710 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PI4KB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12012,358,758 - 12,395,372 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2012,358,762 - 12,394,661 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603811,933,446 - 11,970,304 (+)NCBIVero_WHO_p1.0
Pi4kb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477218,533,603 - 18,564,160 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH128413  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,572,291 - 182,572,511 (+)MAPPERmRatBN7.2
Rnor_6.02196,171,665 - 196,171,884NCBIRnor6.0
Rnor_5.02215,666,351 - 215,666,570UniSTSRnor5.0
RGSC_v3.42189,906,523 - 189,906,742UniSTSRGSC3.4
Celera2175,114,339 - 175,114,558UniSTS
RH 3.4 Map21212.8UniSTS
Cytogenetic Map2q34UniSTS
RH142980  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,569,398 - 182,569,609 (+)MAPPERmRatBN7.2
Rnor_6.02196,168,772 - 196,168,982NCBIRnor6.0
Rnor_5.02215,663,458 - 215,663,668UniSTSRnor5.0
RGSC_v3.42189,903,630 - 189,903,840UniSTSRGSC3.4
Celera2175,111,446 - 175,111,656UniSTS
RH 3.4 Map21196.1UniSTS
Cytogenetic Map2q34UniSTS
RH144445  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,540,402 - 182,540,529 (+)MAPPERmRatBN7.2
Rnor_6.02196,139,781 - 196,139,907NCBIRnor6.0
Rnor_5.02215,634,467 - 215,634,593UniSTSRnor5.0
RGSC_v3.42189,874,639 - 189,874,765UniSTSRGSC3.4
Celera2175,082,442 - 175,082,568UniSTS
RH 3.4 Map21199.1UniSTS
Cytogenetic Map2q34UniSTS
MARC_27466-27467:1034353260:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,561,171 - 182,562,034 (+)MAPPERmRatBN7.2
Rnor_6.02196,160,545 - 196,161,407NCBIRnor6.0
Rnor_5.02215,655,231 - 215,656,093UniSTSRnor5.0
RGSC_v3.42189,895,403 - 189,896,265UniSTSRGSC3.4
Celera2175,103,220 - 175,104,082UniSTS
Cytogenetic Map2q34UniSTS
D3Umi7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,549,029 - 182,549,846 (+)MAPPERmRatBN7.2
Rnor_6.02196,148,406 - 196,149,222NCBIRnor6.0
Rnor_5.02215,643,092 - 215,643,908UniSTSRnor5.0
RGSC_v3.42189,883,264 - 189,884,080UniSTSRGSC3.4
Celera2175,091,071 - 175,091,887UniSTS
Cytogenetic Map2q34UniSTS
REN33561  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,571,864 - 182,572,134 (+)MAPPERmRatBN7.2
Rnor_6.02196,171,238 - 196,171,507NCBIRnor6.0
Rnor_5.02215,665,924 - 215,666,193UniSTSRnor5.0
RGSC_v3.42189,906,096 - 189,906,365UniSTSRGSC3.4
Celera2175,113,912 - 175,114,181UniSTS
Cytogenetic Map2q34UniSTS
REN33651  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22182,549,344 - 182,549,598 (+)MAPPERmRatBN7.2
Rnor_6.02196,148,721 - 196,148,974NCBIRnor6.0
Rnor_5.02215,643,407 - 215,643,660UniSTSRnor5.0
RGSC_v3.42189,883,579 - 189,883,832UniSTSRGSC3.4
Celera2175,091,386 - 175,091,639UniSTS
Cytogenetic Map2q34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168354880185122374Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921184114403Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:39
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000040501
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_591217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC130969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY724527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D84667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000040501   ⟹   ENSRNOP00000039342
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2182,548,848 - 182,588,488 (+)Ensembl
Rnor_6.0 Ensembl2196,139,755 - 196,171,713 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080966   ⟹   ENSRNOP00000070653
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2182,540,567 - 182,572,680 (+)Ensembl
Rnor_6.0 Ensembl2196,145,384 - 196,171,573 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103639   ⟹   ENSRNOP00000082231
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2182,540,572 - 182,588,488 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112486   ⟹   ENSRNOP00000095998
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2182,544,007 - 182,588,488 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112810   ⟹   ENSRNOP00000093461
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2182,540,572 - 182,588,488 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118319   ⟹   ENSRNOP00000089657
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2182,540,572 - 182,572,680 (+)Ensembl
RefSeq Acc Id: NM_031083   ⟹   NP_112345
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,377 - 182,572,409 (+)NCBI
Rnor_6.02196,139,755 - 196,171,782 (+)NCBI
Rnor_5.02215,634,003 - 215,666,743 (+)NCBI
RGSC_v3.42189,874,613 - 189,906,640 (+)RGD
Celera2175,082,416 - 175,114,456 (+)RGD
Sequence:
RefSeq Acc Id: XM_008761333   ⟹   XP_008759555
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,576 - 182,572,684 (+)NCBI
Rnor_6.02196,139,724 - 196,172,055 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008761336   ⟹   XP_008759558
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,575 - 182,572,684 (+)NCBI
Rnor_6.02196,139,724 - 196,172,055 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103230   ⟹   XP_038959158
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,576 - 182,572,684 (+)NCBI
RefSeq Acc Id: XM_039103231   ⟹   XP_038959159
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,576 - 182,572,684 (+)NCBI
RefSeq Acc Id: XM_039103232   ⟹   XP_038959160
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,576 - 182,572,684 (+)NCBI
RefSeq Acc Id: XM_039103233   ⟹   XP_038959161
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,576 - 182,572,684 (+)NCBI
RefSeq Acc Id: XM_039103234   ⟹   XP_038959162
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,575 - 182,572,684 (+)NCBI
RefSeq Acc Id: XM_039103235   ⟹   XP_038959163
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22182,540,576 - 182,572,684 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_112345   ⟸   NM_031083
- UniProtKB: O08561 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008759555   ⟸   XM_008761333
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JYH1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759558   ⟸   XM_008761336
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: ENSRNOP00000070653   ⟸   ENSRNOT00000080966
RefSeq Acc Id: ENSRNOP00000039342   ⟸   ENSRNOT00000040501
RefSeq Acc Id: XP_038959162   ⟸   XM_039103234
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038959159   ⟸   XM_039103231
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038959160   ⟸   XM_039103232
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959158   ⟸   XM_039103230
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038959161   ⟸   XM_039103233
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038959163   ⟸   XM_039103235
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000095998   ⟸   ENSRNOT00000112486
RefSeq Acc Id: ENSRNOP00000093461   ⟸   ENSRNOT00000112810
RefSeq Acc Id: ENSRNOP00000089657   ⟸   ENSRNOT00000118319
RefSeq Acc Id: ENSRNOP00000082231   ⟸   ENSRNOT00000103639
Protein Domains
PI3K/PI4K   PI3K/PI4K catalytic   PIK helical

Protein Structures
Name Modeller Protein Id AA Range Protein Structure Video
AF-O08561-F1-model_v2 AlphaFold O08561 1-816 view protein structure  

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691534
Promoter ID:EPDNEW_R2059
Type:initiation region
Name:Pi4kb_1
Description:phosphatidylinositol 4-kinase beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2060  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02196,139,717 - 196,139,777EPDNEW
RGD ID:13691535
Promoter ID:EPDNEW_R2060
Type:initiation region
Name:Pi4kb_2
Description:phosphatidylinositol 4-kinase beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2059  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02196,139,963 - 196,140,023EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621214 AgrOrtholog
BioCyc Gene G2FUF-52130 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6352 [3-phosphoinositide biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000021024 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000039342 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000070653 UniProtKB/TrEMBL
  ENSRNOP00000082231 ENTREZGENE
  ENSRNOP00000089657 ENTREZGENE
  ENSRNOP00000093461 ENTREZGENE
  ENSRNOP00000095998 ENTREZGENE
Ensembl Transcript ENSRNOT00000040501 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000080966 UniProtKB/TrEMBL
  ENSRNOT00000103639 ENTREZGENE
  ENSRNOT00000112486 ENTREZGENE
  ENSRNOT00000112810 ENTREZGENE
  ENSRNOT00000118319 ENTREZGENE
Gene3D-CATH 1.10.1070.11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3K_accessory_dom UniProtKB/TrEMBL
  PI_Kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PInositide-3_kin_accessory_dom UniProtKB/Swiss-Prot
KEGG Report rno:81747 UniProtKB/Swiss-Prot
NCBI Gene 81747 ENTREZGENE
PANTHER PI_Kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PI3_PI4_kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pi4kb PhenoGen
PROSITE PI3_4_KINASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIK_HELICAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PI3Kc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JYH1 ENTREZGENE, UniProtKB/TrEMBL
  O08561 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Pi4kb  phosphatidylinositol 4-kinase beta  Pi4kb  phosphatidylinositol 4-kinase, catalytic, beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Pi4kb  phosphatidylinositol 4-kinase, catalytic, beta  Pi4kb  phosphatidylinositol 4-kinase, catalytic, beta polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-19 Pi4kb  phosphatidylinositol 4-kinase, catalytic, beta polypeptide  Pik4cb  phosphatidylinositol 4-kinase, catalytic, beta polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Pik4cb  phosphatidylinositol 4-kinase, catalytic, beta polypeptide    phosphatidylinositol 4-kinase  Name updated 1299863 APPROVED
2002-08-07 Pik4cb  phosphatidylinositol 4-kinase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization dispersed in the cytoplasm 633727
gene_expression expressed ubiquitously; present throughout the grey matter of the brain; enriched in fetal brain 633727
gene_protein 816 amino acids; 91.6 kDa 633727