Gene: Prickle2 (prickle planar cell polarity protein 2) Rattus norvegicus
Symbol: Prickle2
Name: prickle planar cell polarity protein 2
Description: ENCODES a protein that exhibits zinc ion binding (inferred); INVOLVED IN blastocyst formation (ortholog); establishment of cell polarity (ortholog); establishment or maintenance of epithelial cell apical/basal polarity (ortholog); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; Wnt signaling pathway; ASSOCIATED WITH benign epilepsy with centrotemporal spikes (ortholog); liver benign neoplasm (ortholog); pre-malignant neoplasm (ortholog); FOUND IN apicolateral plasma membrane (ortholog); cytoplasm (ortholog); lateral plasma membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; all-trans-retinoic acid
Type: protein-coding
Also known as: LOC312563; prickle homolog 2; prickle homolog 2 (Drosophila); prickle-like 2; prickle-like 2 (Drosophila) ; prickle-like protein 2
Homo sapiens (human) : PRICKLE2 (prickle planar cell polarity protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Prickle2 (prickle planar cell polarity protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prickle2 (prickle planar cell polarity protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRICKLE2 (prickle planar cell polarity protein 2)
Canis lupus familiaris (dog) : PRICKLE2 (prickle planar cell polarity protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prickle2 (prickle planar cell polarity protein 2)
Sus scrofa (pig) : PRICKLE2 (prickle planar cell polarity protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04124,238,167 - 124,584,176 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04188,680,318 - 189,025,114 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,571,461 - 126,920,730 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14126,820,833 - 126,938,959 (-)NCBI
Celera4113,786,958 - 114,131,482 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Prickle2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306723
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE