Prickle2 (prickle planar cell polarity protein 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Prickle2 (prickle planar cell polarity protein 2) Rattus norvegicus
Analyze
Symbol: Prickle2
Name: prickle planar cell polarity protein 2
RGD ID: 1306723
Description: Predicted to enable zinc ion binding activity. Predicted to be involved in embryonic brain development and response to electrical stimulus. Predicted to act upstream of or within several processes, including establishment or maintenance of epithelial cell apical/basal polarity; neuron projection development; and trophectodermal cell fate commitment. Predicted to be located in several cellular components, including apicolateral plasma membrane; lateral plasma membrane; and nucleus. Orthologous to human PRICKLE2 (prickle planar cell polarity protein 2); PARTICIPATES IN Wnt signaling, the planar cell polarity pathway; Wnt signaling pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC312563; prickle homolog 2; prickle homolog 2 (Drosophila); prickle-like 2; prickle-like 2 (Drosophila) ; prickle-like protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24124,869,655 - 125,214,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4124,869,552 - 125,214,824 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4130,337,414 - 130,682,587 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04126,111,840 - 126,457,005 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04124,736,392 - 125,081,567 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04124,238,167 - 124,584,176 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4124,238,167 - 124,338,176 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04188,680,318 - 189,025,114 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,571,461 - 126,920,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14126,820,833 - 126,938,959 (-)NCBI
Celera4113,786,958 - 114,131,482 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
crotonaldehyde  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dimethylselenide  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gentamycin  (EXP)
hydroxyl  (ISO)
indometacin  (ISO)
isoflurane  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
trovafloxacin  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Planar cell polarity signaling in vertebrates. Jones C and Chen P, Bioessays. 2007 Feb;29(2):120-32.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17376975   PMID:19788910   PMID:22333836   PMID:26257100  


Genomics

Comparative Map Data
Prickle2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24124,869,655 - 125,214,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4124,869,552 - 125,214,824 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4130,337,414 - 130,682,587 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04126,111,840 - 126,457,005 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04124,736,392 - 125,081,567 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04124,238,167 - 124,584,176 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4124,238,167 - 124,338,176 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04188,680,318 - 189,025,114 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,571,461 - 126,920,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14126,820,833 - 126,938,959 (-)NCBI
Celera4113,786,958 - 114,131,482 (-)NCBICelera
Cytogenetic Map4q34NCBI
PRICKLE2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38364,092,236 - 64,268,173 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl364,092,236 - 64,445,476 (-)EnsemblGRCh38hg38GRCh38
GRCh37364,077,912 - 64,253,849 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36364,054,587 - 64,186,171 (-)NCBINCBI36Build 36hg18NCBI36
Build 34364,054,590 - 64,186,171NCBI
Celera364,096,295 - 64,227,889 (-)NCBICelera
Cytogenetic Map3p14.1NCBI
HuRef364,176,650 - 64,308,225 (-)NCBIHuRef
CHM1_1364,030,867 - 64,162,475 (-)NCBICHM1_1
T2T-CHM13v2.0364,135,847 - 64,311,751 (-)NCBIT2T-CHM13v2.0
Prickle2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39692,347,876 - 92,683,233 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl692,347,889 - 92,683,136 (-)EnsemblGRCm39 Ensembl
GRCm38692,370,891 - 92,706,334 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl692,370,908 - 92,706,155 (-)EnsemblGRCm38mm10GRCm38
MGSCv37692,320,886 - 92,656,178 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36692,341,450 - 92,671,688 (-)NCBIMGSCv36mm8
Celera694,262,178 - 94,597,798 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map641.05NCBI
Prickle2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555171,501,706 - 1,802,169 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555171,501,322 - 1,806,996 (+)NCBIChiLan1.0ChiLan1.0
PRICKLE2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1364,018,177 - 64,372,142 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0363,995,566 - 64,347,679 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1365,374,853 - 65,723,643 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl365,377,760 - 65,723,662 (-)Ensemblpanpan1.1panPan2
PRICKLE2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12026,810,167 - 27,131,864 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2026,809,958 - 27,220,057 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2026,734,821 - 27,056,251 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02026,851,053 - 27,167,684 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2026,850,761 - 27,339,903 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12026,544,737 - 26,865,949 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02026,896,407 - 27,215,887 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02026,956,497 - 27,278,807 (+)NCBIUU_Cfam_GSD_1.0
Prickle2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118163,613,553 - 163,945,169 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366372,003,209 - 2,333,278 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366372,225,400 - 2,299,307 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRICKLE2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1345,620,368 - 45,968,152 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11345,620,372 - 45,968,295 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21350,094,626 - 50,263,960 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRICKLE2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12225,128,160 - 25,481,385 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2225,133,352 - 25,303,131 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041141,333,892 - 141,686,115 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prickle2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248881,537,138 - 1,821,215 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248881,537,080 - 1,825,955 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prickle2
1611 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:643
Count of miRNA genes:290
Interacting mature miRNAs:401
Transcripts:ENSRNOT00000016628
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482798864152731274Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)484728680129854654Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)485253748148090731Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)485253748150276390Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)486730991131730991Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)487327165132327165Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)487327165132327165Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)490850165135850165Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)495174120140174120Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4103194656148194656Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105789505150789505Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106649412151649412Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4106805662151805662Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4116179486151161268Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4119463257147278687Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4120260281147278687Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4120926564148090731Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat

Markers in Region
D4Rat185  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,064,558 - 125,064,778 (+)MAPPERmRatBN7.2
Rnor_6.04124,432,940 - 124,433,159NCBIRnor6.0
Rnor_5.04188,830,973 - 188,831,192UniSTSRnor5.0
RGSC_v3.44126,768,193 - 126,768,412UniSTSRGSC3.4
RGSC_v3.14127,013,034 - 127,013,253RGD
Celera4113,981,892 - 113,982,111UniSTS
SHRSP x BN Map455.5UniSTS
SHRSP x BN Map455.5RGD
Cytogenetic Map4q34UniSTS
D4Rat186  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,121,436 - 125,121,651 (+)MAPPERmRatBN7.2
Rnor_6.04124,489,995 - 124,490,209NCBIRnor6.0
Rnor_5.04188,773,923 - 188,774,137UniSTSRnor5.0
RGSC_v3.44126,825,674 - 126,826,089RGDRGSC3.4
RGSC_v3.44126,825,771 - 126,825,985UniSTSRGSC3.4
RGSC_v3.14127,070,612 - 127,070,826RGD
Celera4114,038,761 - 114,038,975UniSTS
RH 3.4 Map4736.63RGD
RH 3.4 Map4736.63UniSTS
RH 2.0 Map4803.5RGD
SHRSP x BN Map455.49RGD
Cytogenetic Map4q34UniSTS
D4Uia9  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24124,915,758 - 124,915,928 (+)MAPPERmRatBN7.2
Rnor_6.04124,284,598 - 124,284,767NCBIRnor6.0
Rnor_5.04188,979,365 - 188,979,534UniSTSRnor5.0
RGSC_v3.44126,619,585 - 126,619,759RGDRGSC3.4
RGSC_v3.44126,619,586 - 126,619,759UniSTSRGSC3.4
RGSC_v3.14126,864,426 - 126,864,600RGD
Celera4113,833,403 - 113,833,572UniSTS
Cytogenetic Map4q34UniSTS
RH143962  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24125,021,317 - 125,021,431 (+)MAPPERmRatBN7.2
Rnor_6.04124,390,308 - 124,390,421NCBIRnor6.0
Rnor_5.04188,873,711 - 188,873,824UniSTSRnor5.0
RGSC_v3.44126,725,142 - 126,725,255UniSTSRGSC3.4
Celera4113,938,615 - 113,938,728UniSTS
RH 3.4 Map4736.83UniSTS
Cytogenetic Map4q34UniSTS
RH141294  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24124,869,754 - 124,869,936 (+)MAPPERmRatBN7.2
Rnor_6.04124,238,370 - 124,238,551NCBIRnor6.0
Rnor_5.04189,024,730 - 189,024,911UniSTSRnor5.0
RGSC_v3.44126,571,664 - 126,571,845UniSTSRGSC3.4
Celera4113,787,161 - 113,787,342UniSTS
Cytogenetic Map4q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 56 20 27 11
Low 3 43 57 41 19 41 8 10 18 15 12 8
Below cutoff 1 2

Sequence


RefSeq Acc Id: ENSRNOT00000016628   ⟹   ENSRNOP00000016628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4124,869,552 - 125,214,824 (-)Ensembl
Rnor_6.0 Ensembl4124,238,167 - 124,338,176 (-)Ensembl
RefSeq Acc Id: NM_001107876   ⟹   NP_001101346
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24124,869,659 - 125,214,824 (-)NCBI
Rnor_6.04124,238,167 - 124,584,045 (-)NCBI
Rnor_5.04188,680,318 - 189,025,114 (+)NCBI
RGSC_v3.44126,571,461 - 126,920,730 (-)RGD
Celera4113,786,958 - 114,131,482 (-)RGD
Sequence:
RefSeq Acc Id: NM_001415880   ⟹   NP_001402809
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24124,869,659 - 125,044,427 (-)NCBI
RefSeq Acc Id: NM_001415881   ⟹   NP_001402810
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24124,869,659 - 124,990,294 (-)NCBI
RefSeq Acc Id: XM_039107620   ⟹   XP_038963548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24124,869,655 - 125,214,860 (-)NCBI
RefSeq Acc Id: XM_039107621   ⟹   XP_038963549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24124,869,655 - 125,214,859 (-)NCBI
RefSeq Acc Id: XM_039107624   ⟹   XP_038963552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24124,894,975 - 125,214,862 (-)NCBI
RefSeq Acc Id: NP_001101346   ⟸   NM_001107876
- UniProtKB: A6IBC5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016628   ⟸   ENSRNOT00000016628
RefSeq Acc Id: XP_038963548   ⟸   XM_039107620
- Peptide Label: isoform X1
- UniProtKB: F1M0J7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963549   ⟸   XM_039107621
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038963552   ⟸   XM_039107624
- Peptide Label: isoform X4
RefSeq Acc Id: NP_001402809   ⟸   NM_001415880
- UniProtKB: A6IBC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402810   ⟸   NM_001415881
- UniProtKB: A6IBC5 (UniProtKB/TrEMBL)
Protein Domains
LIM zinc-binding   PET

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M0J7-F1-model_v2 AlphaFold F1M0J7 1-847 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306723 AgrOrtholog
BioCyc Gene G2FUF-43692 BioCyc
Ensembl Genes ENSRNOG00000012364 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016628 ENTREZGENE
  ENSRNOT00000016628.7 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro LIM1_prickle UniProtKB/TrEMBL
  LIM2_prickle UniProtKB/TrEMBL
  LIM3_prickle UniProtKB/TrEMBL
  PET_domain UniProtKB/TrEMBL
  PET_prickle UniProtKB/TrEMBL
  Pk/Esn/Tes UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
KEGG Report rno:312563 UniProtKB/TrEMBL
NCBI Gene 312563 ENTREZGENE
PANTHER LIM DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PRICKLE-LIKE PROTEIN 2 UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
  PET UniProtKB/TrEMBL
PhenoGen Prickle2 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
  PET UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012364 RatGTEx
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A6IBC5 ENTREZGENE, UniProtKB/TrEMBL
  F1M0J7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-21 Prickle2  prickle planar cell polarity protein 2  Prickle2  prickle homolog 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-30 Prickle2  prickle homolog 2  Prickle2  prickle homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Prickle2  prickle homolog 2 (Drosophila)  Prickle2  prickle-like 2 (Drosophila)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Prickle2  prickle-like 2 (Drosophila)   Prickle2_predicted  prickle-like 2 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Prickle2_predicted  prickle-like 2 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED