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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306723
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prickle2
Name: prickle planar cell polarity protein 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prickle2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PRICKLE2 mRNAPMID:25181051
Prickle2increases expressionEXP 6480464CTDbisphenol A results in increased expression of PRICKLE2 mRNAPMID:30816183
Prickle2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of PRICKLE2 genePMID:28505145
Prickle2increases expressionISOPRICKLE2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of PRICKLE2 mRNAPMID:29275510
Prickle2multiple interactionsISOPRICKLE2 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PRICKLE2 mRNAPMID:28628672
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