GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Prickle2 | decreases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of PRICKLE2 mRNA | PMID:21839799 | Prickle2 | affects methylation | ISO | PRICKLE2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of PRICKLE2 5' UTR; Benzo(a)pyrene affects the methylation of PRICKLE2 exon; Benzo(a)pyrene affects the methylation of PRICKLE2 promoter | PMID:27901495 | Prickle2 | decreases methylation | ISO | Prickle2 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of PRICKLE2 intron | PMID:27901495 | Prickle2 | increases methylation | ISO | PRICKLE2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased methylation of PRICKLE2 3' UTR | PMID:27901495 | Prickle2 | increases mutagenesis | ISO | PRICKLE2 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased mutagenesis of PRICKLE2 gene | PMID:25435355 | |
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